-
1
-
-
44649139364
-
HIV-1 accessory proteins-ensuring viral survival in a hostile environment
-
Malim MH, Emerman M: HIV-1 accessory proteins-ensuring viral survival in a hostile environment. Cell Host Microbe 2008, 3:388-398.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 388-398
-
-
Malim, M.H.1
Emerman, M.2
-
2
-
-
84890125460
-
HIV accessory proteins versus host restriction factors
-
Strebel K: HIV accessory proteins versus host restriction factors. Curr Opin Virol 2013, 3:692-699.
-
(2013)
Curr Opin Virol
, vol.3
, pp. 692-699
-
-
Strebel, K.1
-
3
-
-
77950646448
-
Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr?
-
Ayinde D, Maudet C, Transy C, Margottin-Goguet F: Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr? Retrovirology 2010, 7:35.
-
(2010)
Retrovirology
, vol.7
, pp. 35
-
-
Ayinde, D.1
Maudet, C.2
Transy, C.3
Margottin-Goguet, F.4
-
4
-
-
0028853961
-
Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity
-
He J, Choe S, Walker R, Di Marzio P, Morgan DO, Landau NR: Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity. J Virol 1995, 69:6705-6711.
-
(1995)
J Virol
, vol.69
, pp. 6705-6711
-
-
He, J.1
Choe, S.2
Walker, R.3
Marzio, P.4
Morgan, D.O.5
Landau, N.R.6
-
5
-
-
0029165291
-
The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2+M phase of the cell cycle
-
Jowett JB, Planelles V, Poon B, Shah NP, Chen ML, Chen IS: The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2+M phase of the cell cycle. J Virol 1995, 69:6304-6313.
-
(1995)
J Virol
, vol.69
, pp. 6304-6313
-
-
Jowett, J.B.1
Planelles, V.2
Poon, B.3
Shah, N.P.4
Chen, M.L.5
Chen, I.S.6
-
6
-
-
0029126614
-
Fate of the human immunodeficiency virus type 1 provirus in infected cells: a role for vpr
-
Planelles V, Bachelerie F, Jowett JB, Haislip A, Xie Y, Banooni P, Masuda T, Chen IS: Fate of the human immunodeficiency virus type 1 provirus in infected cells: a role for vpr. J Virol 1995, 69:5883-5889.
-
(1995)
J Virol
, vol.69
, pp. 5883-5889
-
-
Planelles, V.1
Bachelerie, F.2
Jowett, J.B.3
Haislip, A.4
Xie, Y.5
Banooni, P.6
Masuda, T.7
Chen, I.S.8
-
7
-
-
0028801303
-
Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B
-
Re F, Braaten D, Franke EK, Luban J: Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B. J Virol 1995, 69:6859-6864.
-
(1995)
J Virol
, vol.69
, pp. 6859-6864
-
-
Re, F.1
Braaten, D.2
Franke, E.K.3
Luban, J.4
-
8
-
-
0028813107
-
The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection
-
Rogel ME, Wu LI, Emerman M: The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection. J Virol 1995, 69:882-888.
-
(1995)
J Virol
, vol.69
, pp. 882-888
-
-
Rogel, M.E.1
Wu, L.I.2
Emerman, M.3
-
9
-
-
0028297360
-
Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: mutational analysis of a primary HIV-1 isolate
-
Balliet JW, Kolson DL, Eiger G, Kim FM, McGann KA, Srinivasan A, Collman R: Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: mutational analysis of a primary HIV-1 isolate. Virology 1994, 200:623-631.
-
(1994)
Virology
, vol.200
, pp. 623-631
-
-
Balliet, J.W.1
Kolson, D.L.2
Eiger, G.3
Kim, F.M.4
McGann, K.A.5
Srinivasan, A.6
Collman, R.7
-
10
-
-
0028842207
-
Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes
-
Connor RI, Chen BK, Choe S, Landau NR: Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology 1995, 206:935-944.
-
(1995)
Virology
, vol.206
, pp. 935-944
-
-
Connor, R.I.1
Chen, B.K.2
Choe, S.3
Landau, N.R.4
-
11
-
-
0035914839
-
HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells
-
Eckstein DA, Sherman MP, Penn ML, Chin PS, De Noronha CM, Greene WC, Goldsmith MA: HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells. J Exp Med 2001, 194:1407-1419.
-
(2001)
J Exp Med
, vol.194
, pp. 1407-1419
-
-
Eckstein, D.A.1
Sherman, M.P.2
Penn, M.L.3
Chin, P.S.4
Noronha, C.M.5
Greene, W.C.6
Goldsmith, M.A.7
-
12
-
-
38649100975
-
Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages
-
Jacquot G, Le Rouzic E, David A, Mazzolini J, Bouchet J, Bouaziz S, Niedergang F, Pancino G, Benichou S: Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages. Retrovirology 2007, 4:84.
-
(2007)
Retrovirology
, vol.4
, pp. 84
-
-
Jacquot, G.1
Rouzic, E.2
David, A.3
Mazzolini, J.4
Bouchet, J.5
Bouaziz, S.6
Niedergang, F.7
Pancino, G.8
Benichou, S.9
-
13
-
-
84892799863
-
Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing
-
Laguette N, Bregnard C, Hue P, Basbous J, Yatim A, Larroque M, Kirchhoff F, Constantinou A, Sobhian B, Benkirane M: Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing. Cell 2014, 156:134-145.
-
(2014)
Cell
, vol.156
, pp. 134-145
-
-
Laguette, N.1
Bregnard, C.2
Hue, P.3
Basbous, J.4
Yatim, A.5
Larroque, M.6
Kirchhoff, F.7
Constantinou, A.8
Sobhian, B.9
Benkirane, M.10
-
14
-
-
11444257728
-
The role of Vpr in HIV-1 pathogenesis
-
Andersen JL, Planelles V: The role of Vpr in HIV-1 pathogenesis. Curr HIV Res 2005, 3:43-51.
-
(2005)
Curr HIV Res
, vol.3
, pp. 43-51
-
-
Andersen, J.L.1
Planelles, V.2
-
15
-
-
29744464493
-
Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo
-
Lai M, Zimmerman ES, Planelles V, Chen J: Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo. J Virol 2005, 79:15443-15451.
-
(2005)
J Virol
, vol.79
, pp. 15443-15451
-
-
Lai, M.1
Zimmerman, E.S.2
Planelles, V.3
Chen, J.4
-
16
-
-
0037830710
-
Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R
-
Roshal M, Kim B, Zhu Y, Nghiem P, Planelles V: Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R. J Biol Chem 2003, 278:25879-25886.
-
(2003)
J Biol Chem
, vol.278
, pp. 25879-25886
-
-
Roshal, M.1
Kim, B.2
Zhu, Y.3
Nghiem, P.4
Planelles, V.5
-
17
-
-
73349122322
-
HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response
-
Ward J, Davis Z, DeHart J, Zimmerman E, Bosque A, Brunetta E, Mavilio D, Planelles V, Barker E: HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response. PLoS Pathog 2009, 5:e1000613.
-
(2009)
PLoS Pathog
, vol.5
-
-
Ward, J.1
Davis, Z.2
DeHart, J.3
Zimmerman, E.4
Bosque, A.5
Brunetta, E.6
Mavilio, D.7
Planelles, V.8
Barker, E.9
-
18
-
-
6344227897
-
Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation
-
Zimmerman ES, Chen J, Andersen JL, Ardon O, Dehart JL, Blackett J, Choudhary SK, Camerini D, Nghiem P, Planelles V: Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation. Mol Cell Biol 2004, 24:9286-9294.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9286-9294
-
-
Zimmerman, E.S.1
Chen, J.2
Andersen, J.L.3
Ardon, O.4
Dehart, J.L.5
Blackett, J.6
Choudhary, S.K.7
Camerini, D.8
Nghiem, P.9
Planelles, V.10
-
19
-
-
33750284306
-
Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo
-
Zimmerman ES, Sherman MP, Blackett JL, Neidleman JA, Kreis C, Mundt P, Williams SA, Warmerdam M, Kahn J, Hecht FM, Grant RM, de Noronha CM, Weyrich AS, Greene WC, Planelles V: Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. J Virol 2006, 80:10407-10418.
-
(2006)
J Virol
, vol.80
, pp. 10407-10418
-
-
Zimmerman, E.S.1
Sherman, M.P.2
Blackett, J.L.3
Neidleman, J.A.4
Kreis, C.5
Mundt, P.6
Williams, S.A.7
Warmerdam, M.8
Kahn, J.9
Hecht, F.M.10
Grant, R.M.11
Noronha, C.M.12
Weyrich, A.S.13
Greene, W.C.14
Planelles, V.15
-
20
-
-
84891301320
-
Causes and consequences of replication stress
-
Zeman MK, Cimprich KA: Causes and consequences of replication stress. Nat Cell Biol 2014, 16:2-9.
-
(2014)
Nat Cell Biol
, vol.16
, pp. 2-9
-
-
Zeman, M.K.1
Cimprich, K.A.2
-
21
-
-
17144398064
-
ATR and GADD45alpha mediate HIV-1 Vpr-induced apoptosis
-
Andersen JL, Zimmerman ES, DeHart JL, Murala S, Ardon O, Blackett J, Chen J, Planelles V: ATR and GADD45alpha mediate HIV-1 Vpr-induced apoptosis. Cell Death Differ 2005, 12:326-334.
-
(2005)
Cell Death Differ
, vol.12
, pp. 326-334
-
-
Andersen, J.L.1
Zimmerman, E.S.2
DeHart, J.L.3
Murala, S.4
Ardon, O.5
Blackett, J.6
Chen, J.7
Planelles, V.8
-
22
-
-
34547639932
-
HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase
-
Belzile JP, Duisit G, Rougeau N, Mercier J, Finzi A, Cohen EA: HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase. PLoS Pathog 2007, 3:e85.
-
(2007)
PLoS Pathog
, vol.3
-
-
Belzile, J.P.1
Duisit, G.2
Rougeau, N.3
Mercier, J.4
Finzi, A.5
Cohen, E.A.6
-
23
-
-
77954251074
-
Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R
-
Li G, Park HU, Liang D, Zhao RY: Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R. Retrovirology 2010, 7:59.
-
(2010)
Retrovirology
, vol.7
, pp. 59
-
-
Li, G.1
Park, H.U.2
Liang, D.3
Zhao, R.Y.4
-
24
-
-
34347376505
-
HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system
-
DeHart JL, Zimmerman ES, Ardon O, Monteiro-Filho CM, Arganaraz ER, Planelles V: HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system. Virol J 2007, 4:57.
-
(2007)
Virol J
, vol.4
, pp. 57
-
-
DeHart, J.L.1
Zimmerman, E.S.2
Ardon, O.3
Monteiro-Filho, C.M.4
Arganaraz, E.R.5
Planelles, V.6
-
25
-
-
34547395804
-
Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle
-
Hrecka K, Gierszewska M, Srivastava S, Kozaczkiewicz L, Swanson SK, Florens L, Washburn MP, Skowronski J: Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle. Proc Natl Acad Sci U S A 2007, 104:11778-11783.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 11778-11783
-
-
Hrecka, K.1
Gierszewska, M.2
Srivastava, S.3
Kozaczkiewicz, L.4
Swanson, S.K.5
Florens, L.6
Washburn, M.P.7
Skowronski, J.8
-
26
-
-
33846899500
-
HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase
-
Le Rouzic E, Belaidouni N, Estrabaud E, Morel M, Rain JC, Transy C, Margottin-Goguet F: HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase. Cell Cycle 2007, 6:182-188.
-
(2007)
Cell Cycle
, vol.6
, pp. 182-188
-
-
Rouzic, E.1
Belaidouni, N.2
Estrabaud, E.3
Morel, M.4
Rain, J.C.5
Transy, C.6
Margottin-Goguet, F.7
-
27
-
-
34247187942
-
HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1
-
Schrofelbauer B, Hakata Y, Landau NR: HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1. Proc Natl Acad Sci U S A 2007, 104:4130-4135.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 4130-4135
-
-
Schrofelbauer, B.1
Hakata, Y.2
Landau, N.R.3
-
28
-
-
34648833229
-
DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest
-
Tan L, Ehrlich E, Yu XF: DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest. J Virol 2007, 81:10822-10830.
-
(2007)
J Virol
, vol.81
, pp. 10822-10830
-
-
Tan, L.1
Ehrlich, E.2
Yu, X.F.3
-
29
-
-
34848911347
-
The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor
-
Wen X, Duus KM, Friedrich TD, de Noronha CM: The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor. J Biol Chem 2007, 282:27046-27057.
-
(2007)
J Biol Chem
, vol.282
, pp. 27046-27057
-
-
Wen, X.1
Duus, K.M.2
Friedrich, T.D.3
Noronha, C.M.4
-
30
-
-
0028318421
-
Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein
-
Zhao LJ, Mukherjee S, Narayan O: Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein. J Biol Chem 1994, 269:15577-15582.
-
(1994)
J Biol Chem
, vol.269
, pp. 15577-15582
-
-
Zhao, L.J.1
Mukherjee, S.2
Narayan, O.3
-
31
-
-
33749535905
-
Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery
-
Angers S, Li T, Yi X, MacCoss MJ, Moon RT, Zheng N: Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Nature 2006, 443:590-593.
-
(2006)
Nature
, vol.443
, pp. 590-593
-
-
Angers, S.1
Li, T.2
Yi, X.3
MacCoss, M.J.4
Moon, R.T.5
Zheng, N.6
-
32
-
-
33751112293
-
DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases
-
He YJ, McCall CM, Hu J, Zeng Y, Xiong Y: DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases. Genes Dev 2006, 20:2949-2954.
-
(2006)
Genes Dev
, vol.20
, pp. 2949-2954
-
-
He, Y.J.1
McCall, C.M.2
Hu, J.3
Zeng, Y.4
Xiong, Y.5
-
33
-
-
34248209547
-
Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy
-
Higa LA, Zhang H: Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy. Cell Div 2007, 2:5.
-
(2007)
Cell Div
, vol.2
, pp. 5
-
-
Higa, L.A.1
Zhang, H.2
-
34
-
-
33747873322
-
A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1
-
Jin J, Arias EE, Chen J, Harper JW, Walter JC: A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. Mol Cell 2006, 23:709-721.
-
(2006)
Mol Cell
, vol.23
, pp. 709-721
-
-
Jin, J.1
Arias, E.E.2
Chen, J.3
Harper, J.W.4
Walter, J.C.5
-
35
-
-
52049095759
-
Assembly with the Cul4A-DDB1DCAF1 ubiquitin ligase protects HIV-1 Vpr from proteasomal degradation
-
Le Rouzic E, Morel M, Ayinde D, Belaidouni N, Letienne J, Transy C, Margottin-Goguet F: Assembly with the Cul4A-DDB1DCAF1 ubiquitin ligase protects HIV-1 Vpr from proteasomal degradation. J Biol Chem 2008, 283:21686-21692.
-
(2008)
J Biol Chem
, vol.283
, pp. 21686-21692
-
-
Rouzic, E.1
Morel, M.2
Ayinde, D.3
Belaidouni, N.4
Letienne, J.5
Transy, C.6
Margottin-Goguet, F.7
-
36
-
-
79251611165
-
Mutations of the SLX4 gene in Fanconi anemia
-
Kim Y, Lach FP, Desetty R, Hanenberg H, Auerbach AD, Smogorzewska A: Mutations of the SLX4 gene in Fanconi anemia. Nat Genet 2011, 43:142-146.
-
(2011)
Nat Genet
, vol.43
, pp. 142-146
-
-
Kim, Y.1
Lach, F.P.2
Desetty, R.3
Hanenberg, H.4
Auerbach, A.D.5
Smogorzewska, A.6
-
37
-
-
79251632658
-
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype
-
Stoepker C, Hain K, Schuster B, Hilhorst-Hofstee Y, Rooimans MA, Steltenpool J, Oostra AB, Eirich K, Korthof ET, Nieuwint AW, Jaspers NG, Bettecken T, Joenje H, Schindler D, Rouse J, de Winter JP: SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet 2011, 43:138-141.
-
(2011)
Nat Genet
, vol.43
, pp. 138-141
-
-
Stoepker, C.1
Hain, K.2
Schuster, B.3
Hilhorst-Hofstee, Y.4
Rooimans, M.A.5
Steltenpool, J.6
Oostra, A.B.7
Eirich, K.8
Korthof, E.T.9
Nieuwint, A.W.10
Jaspers, N.G.11
Bettecken, T.12
Joenje, H.13
Schindler, D.14
Rouse, J.15
Winter, J.P.16
-
38
-
-
67649641641
-
Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair
-
Munoz IM, Hain K, Declais AC, Gardiner M, Toh GW, Sanchez-Pulido L, Heuckmann JM, Toth R, Macartney T, Eppink B, Kanaar R, Ponting CP, Lilley DM, Rouse J: Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair. Mol Cell 2009, 35:116-127.
-
(2009)
Mol Cell
, vol.35
, pp. 116-127
-
-
Munoz, I.M.1
Hain, K.2
Declais, A.C.3
Gardiner, M.4
Toh, G.W.5
Sanchez-Pulido, L.6
Heuckmann, J.M.7
Toth, R.8
Macartney, T.9
Eppink, B.10
Kanaar, R.11
Ponting, C.P.12
Lilley, D.M.13
Rouse, J.14
-
39
-
-
67649662604
-
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
-
Svendsen JM, Smogorzewska A, Sowa ME, O'Connell BC, Gygi SP, Elledge SJ, Harper JW: Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Cell 2009, 138:63-77.
-
(2009)
Cell
, vol.138
, pp. 63-77
-
-
Svendsen, J.M.1
Smogorzewska, A.2
Sowa, M.E.3
O'Connell, B.C.4
Gygi, S.P.5
Elledge, S.J.6
Harper, J.W.7
-
40
-
-
67649655402
-
Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases
-
Fekairi S, Scaglione S, Chahwan C, Taylor ER, Tissier A, Coulon S, Dong MQ, Ruse C, Yates JR 3rd, Russell P, Fuchs RP, McGowan CH, Gaillard PH: Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases. Cell 2009, 138:78-89.
-
(2009)
Cell
, vol.138
, pp. 78-89
-
-
Fekairi, S.1
Scaglione, S.2
Chahwan, C.3
Taylor, E.R.4
Tissier, A.5
Coulon, S.6
Dong, M.Q.7
Ruse, C.8
Yates, J.R.9
Russell, P.10
Fuchs, R.P.11
McGowan, C.H.12
Gaillard, P.H.13
-
41
-
-
84886241606
-
Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells
-
Wyatt HD, Sarbajna S, Matos J, West SC: Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells. Mol Cell 2013, 52:234-247.
-
(2013)
Mol Cell
, vol.52
, pp. 234-247
-
-
Wyatt, H.D.1
Sarbajna, S.2
Matos, J.3
West, S.C.4
-
42
-
-
84885855405
-
Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions
-
Garner E, Kim Y, Lach FP, Kottemann MC, Smogorzewska A: Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions. Cell Rep 2013, 5:207-215.
-
(2013)
Cell Rep
, vol.5
, pp. 207-215
-
-
Garner, E.1
Kim, Y.2
Lach, F.P.3
Kottemann, M.C.4
Smogorzewska, A.5
-
43
-
-
84886251421
-
Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases
-
Castor D, Nair N, Declais AC, Lachaud C, Toth R, Macartney TJ, Lilley DM, Arthur JS, Rouse J: Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases. Mol Cell 2013, 52:221-233.
-
(2013)
Mol Cell
, vol.52
, pp. 221-233
-
-
Castor, D.1
Nair, N.2
Declais, A.C.3
Lachaud, C.4
Toth, R.5
Macartney, T.J.6
Lilley, D.M.7
Arthur, J.S.8
Rouse, J.9
-
44
-
-
85027953032
-
Regulation of Mus81-Eme1 Holliday junction resolvase in response to DNA damage
-
Dehe PM, Coulon S, Scaglione S, Shanahan P, Takedachi A, Wohlschlegel JA, Yates JR 3rd, Llorente B, Russell P, Gaillard PH: Regulation of Mus81-Eme1 Holliday junction resolvase in response to DNA damage. Nat Struct Mol Biol 2013, 20:598-603.
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 598-603
-
-
Dehe, P.M.1
Coulon, S.2
Scaglione, S.3
Shanahan, P.4
Takedachi, A.5
Wohlschlegel, J.A.6
Yates, J.R.7
Llorente, B.8
Russell, P.9
Gaillard, P.H.10
-
45
-
-
84866912764
-
Cell cycle-dependent regulation of the nuclease activity of Mus81-Eme1/Mms4
-
Gallo-Fernandez M, Saugar I, Ortiz-Bazan MA, Vazquez MV, Tercero JA: Cell cycle-dependent regulation of the nuclease activity of Mus81-Eme1/Mms4. Nucleic Acids Res 2012, 40:8325-8335.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 8325-8335
-
-
Gallo-Fernandez, M.1
Saugar, I.2
Ortiz-Bazan, M.A.3
Vazquez, M.V.4
Tercero, J.A.5
-
46
-
-
80053544629
-
Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis
-
Matos J, Blanco MG, Maslen S, Skehel JM, West SC: Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis. Cell 2011, 147:158-172.
-
(2011)
Cell
, vol.147
, pp. 158-172
-
-
Matos, J.1
Blanco, M.G.2
Maslen, S.3
Skehel, J.M.4
West, S.C.5
-
47
-
-
84892432014
-
Cell-cycle kinases coordinate the resolution of recombination intermediates with chromosome segregation
-
Matos J, Blanco MG, West SC: Cell-cycle kinases coordinate the resolution of recombination intermediates with chromosome segregation. Cell Rep 2013, 4:76-86.
-
(2013)
Cell Rep
, vol.4
, pp. 76-86
-
-
Matos, J.1
Blanco, M.G.2
West, S.C.3
-
48
-
-
84885968281
-
Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage
-
Saugar I, Vazquez MV, Gallo-Fernandez M, Ortiz-Bazan MA, Segurado M, Calzada A, Tercero JA: Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage. Nucleic Acids Res 2013, 41:8943-8958.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 8943-8958
-
-
Saugar, I.1
Vazquez, M.V.2
Gallo-Fernandez, M.3
Ortiz-Bazan, M.A.4
Segurado, M.5
Calzada, A.6
Tercero, J.A.7
-
49
-
-
84924171368
-
G2/M cell cycle arrest correlates with primate lentiviral Vpr interaction with the SLX4 complex
-
Berger G, Lawrence M, Hue S, Neil SJ
-
(2014)
J Virol
-
-
-
50
-
-
84863670930
-
Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway
-
Kim H, D'Andrea AD: Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. Genes Dev 2012, 26:1393-1408.
-
(2012)
Genes Dev
, vol.26
, pp. 1393-1408
-
-
Kim, H.1
D'Andrea, A.D.2
-
51
-
-
31544471786
-
HIV-1 Vpr induces DNA double-strand breaks
-
Tachiwana H, Shimura M, Nakai-Murakami C, Tokunaga K, Takizawa Y, Sata T, Kurumizaka H, Ishizaka Y: HIV-1 Vpr induces DNA double-strand breaks. Cancer Res 2006, 66:627-631.
-
(2006)
Cancer Res
, vol.66
, pp. 627-631
-
-
Tachiwana, H.1
Shimura, M.2
Nakai-Murakami, C.3
Tokunaga, K.4
Takizawa, Y.5
Sata, T.6
Kurumizaka, H.7
Ishizaka, Y.8
-
52
-
-
35848930133
-
The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks
-
Hanada K, Budzowska M, Davies SL, van Drunen E, Onizawa H, Beverloo HB, Maas A, Essers J, Hickson ID, Kanaar R: The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks. Nat Struct Mol Biol 2007, 14:1096-1104.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 1096-1104
-
-
Hanada, K.1
Budzowska, M.2
Davies, S.L.3
Drunen, E.4
Onizawa, H.5
Beverloo, H.B.6
Maas, A.7
Essers, J.8
Hickson, I.D.9
Kanaar, R.10
-
53
-
-
59649123419
-
Modulation of dendritic cell function by persistent viruses
-
Liu B, Woltman AM, Janssen HL, Boonstra A: Modulation of dendritic cell function by persistent viruses. J Leukoc Biol 2009, 85:205-214.
-
(2009)
J Leukoc Biol
, vol.85
, pp. 205-214
-
-
Liu, B.1
Woltman, A.M.2
Janssen, H.L.3
Boonstra, A.4
-
54
-
-
70349748582
-
Human immunodeficiency virus type 1 mediates global disruption of innate antiviral signaling and immune defenses within infected cells
-
Doehle BP, Hladik F, McNevin JP, McElrath MJ, Gale M Jr: Human immunodeficiency virus type 1 mediates global disruption of innate antiviral signaling and immune defenses within infected cells. J Virol 2009, 83:10395-10405.
-
(2009)
J Virol
, vol.83
, pp. 10395-10405
-
-
Doehle, B.P.1
Hladik, F.2
McNevin, J.P.3
McElrath, M.J.4
Gale, M.5
-
55
-
-
40649114040
-
HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation
-
Okumura A, Alce T, Lubyova B, Ezelle H, Strebel K, Pitha PM: HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation. Virology 2008, 373:85-97.
-
(2008)
Virology
, vol.373
, pp. 85-97
-
-
Okumura, A.1
Alce, T.2
Lubyova, B.3
Ezelle, H.4
Strebel, K.5
Pitha, P.M.6
-
56
-
-
64749100822
-
HIV-1 mediated immune pathogenesis: spotlight on the role of viral protein R (Vpr)
-
Majumder B, Venkatachari NJ, Srinivasan A, Ayyavoo V: HIV-1 mediated immune pathogenesis: spotlight on the role of viral protein R (Vpr). Curr HIV Res 2009, 7:169-177.
-
(2009)
Curr HIV Res
, vol.7
, pp. 169-177
-
-
Majumder, B.1
Venkatachari, N.J.2
Srinivasan, A.3
Ayyavoo, V.4
-
57
-
-
84892843079
-
HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo
-
Sato K, Misawa N, Iwami S, Satou Y, Matsuoka M, Ishizaka Y, Ito M, Aihara K, An DS, Koyanagi Y: HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo. PLoS Pathog 2013, 9:e1003812.
-
(2013)
PLoS Pathog
, vol.9
-
-
Sato, K.1
Misawa, N.2
Iwami, S.3
Satou, Y.4
Matsuoka, M.5
Ishizaka, Y.6
Ito, M.7
Aihara, K.8
An, D.S.9
Koyanagi, Y.10
-
58
-
-
0035025888
-
A quantitative assay for HIV DNA integration in vivo
-
Butler SL, Hansen MS, Bushman FD: A quantitative assay for HIV DNA integration in vivo. Nat Med 2001, 7:631-634.
-
(2001)
Nat Med
, vol.7
, pp. 631-634
-
-
Butler, S.L.1
Hansen, M.S.2
Bushman, F.D.3
-
59
-
-
77958114725
-
The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1
-
Yan N, Regalado-Magdos AD, Stiggelbout B, Lee-Kirsch MA, Lieberman J: The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1. Nat Immunol 2010, 11:1005-1013.
-
(2010)
Nat Immunol
, vol.11
, pp. 1005-1013
-
-
Yan, N.1
Regalado-Magdos, A.D.2
Stiggelbout, B.3
Lee-Kirsch, M.A.4
Lieberman, J.5
-
60
-
-
84906919951
-
HIV-1 Vpr Induces Interferon-Stimulated Genes in Human Monocyte-Derived Macrophages
-
Zahoor MA, Xue G, Sato H, Murakami T, Takeshima SN, Aida Y: HIV-1 Vpr Induces Interferon-Stimulated Genes in Human Monocyte-Derived Macrophages. PLoS One 2014, 9:e106418.
-
(2014)
PLoS One
, vol.9
-
-
Zahoor, M.A.1
Xue, G.2
Sato, H.3
Murakami, T.4
Takeshima, S.N.5
Aida, Y.6
-
61
-
-
84857347109
-
The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx
-
Lim ES, Fregoso OI, McCoy CO, Matsen FA, Malik HS, Emerman M: The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx. Cell Host Microbe 2012, 11:194-204.
-
(2012)
Cell Host Microbe
, vol.11
, pp. 194-204
-
-
Lim, E.S.1
Fregoso, O.I.2
McCoy, C.O.3
Matsen, F.A.4
Malik, H.S.5
Emerman, M.6
-
62
-
-
79959858243
-
Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein
-
Hrecka K, Hao C, Gierszewska M, Swanson SK, Kesik-Brodacka M, Srivastava S, Florens L, Washburn MP, Skowronski J: Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein. Nature 2011, 474:658-661.
-
(2011)
Nature
, vol.474
, pp. 658-661
-
-
Hrecka, K.1
Hao, C.2
Gierszewska, M.3
Swanson, S.K.4
Kesik-Brodacka, M.5
Srivastava, S.6
Florens, L.7
Washburn, M.P.8
Skowronski, J.9
-
63
-
-
79959843617
-
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
-
Laguette N, Sobhian B, Casartelli N, Ringeard M, Chable-Bessia C, Segeral E, Yatim A, Emiliani S, Schwartz O, Benkirane M: SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx. Nature 2011, 474:654-657.
-
(2011)
Nature
, vol.474
, pp. 654-657
-
-
Laguette, N.1
Sobhian, B.2
Casartelli, N.3
Ringeard, M.4
Chable-Bessia, C.5
Segeral, E.6
Yatim, A.7
Emiliani, S.8
Schwartz, O.9
Benkirane, M.10
-
64
-
-
84897585594
-
SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage
-
Clifford R, Louis T, Robbe P, Ackroyd S, Burns A, Timbs AT, Wright Colopy G, Dreau H, Sigaux F, Judde JG, Rotger M, Telenti A, Lin YL, Pasero P, Maelfait J, Titsias M, Cohen DR, Henderson SJ, Ross MT, Bentley D, Hillmen P, Pettitt A, Rehwinkel J, Knight SJ, Taylor JC, Crow YJ, Benkirane M, Schuh A: SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage. Blood 2014, 123:1021-1031.
-
(2014)
Blood
, vol.123
, pp. 1021-1031
-
-
Clifford, R.1
Louis, T.2
Robbe, P.3
Ackroyd, S.4
Burns, A.5
Timbs, A.T.6
Wright Colopy, G.7
Dreau, H.8
Sigaux, F.9
Judde, J.G.10
Rotger, M.11
Telenti, A.12
Lin, Y.L.13
Pasero, P.14
Maelfait, J.15
Titsias, M.16
Cohen, D.R.17
Henderson, S.J.18
Ross, M.T.19
Bentley, D.20
Hillmen, P.21
Pettitt, A.22
Rehwinkel, J.23
Knight, S.J.24
Taylor, J.C.25
Crow, Y.J.26
Benkirane, M.27
Schuh, A.28
more..
-
65
-
-
67649861901
-
Mutations involved in Aicardi-Goutieres syndrome implicate SAMHD1 as regulator of the innate immune response
-
Rice GI, Bond J, Asipu A, Brunette RL, Manfield IW, Carr IM, Fuller JC, Jackson RM, Lamb T, Briggs TA, Ali M, Gornall H, Couthard LR, Aeby A, Attard-Montalto SP, Bertini E, Bodemer C, Brockmann K, Brueton LA, Corry PC, Desguerre I, Fazzi E, Cazorla AG, Gener B, Hamel BC, Heiberg A, Hunter M, van der Knaap MS, Kumar R, Lagae L, et al: Mutations involved in Aicardi-Goutieres syndrome implicate SAMHD1 as regulator of the innate immune response. Nat Genet 2009, 41:829-832.
-
(2009)
Nat Genet
, vol.41
, pp. 829-832
-
-
Rice, G.I.1
Bond, J.2
Asipu, A.3
Brunette, R.L.4
Manfield, I.W.5
Carr, I.M.6
Fuller, J.C.7
Jackson, R.M.8
Lamb, T.9
Briggs, T.A.10
Ali, M.11
Gornall, H.12
Couthard, L.R.13
Aeby, A.14
Attard-Montalto, S.P.15
Bertini, E.16
Bodemer, C.17
Brockmann, K.18
Brueton, L.A.19
Corry, P.C.20
Desguerre, I.21
Fazzi, E.22
Cazorla, A.G.23
Gener, B.24
Hamel, B.C.25
Heiberg, A.26
Hunter, M.27
Knaap, M.S.28
Kumar, R.29
Lagae, L.30
more..
-
66
-
-
84855272511
-
SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutieres syndrome are highly susceptible to HIV-1 infection
-
Berger A, Sommer AF, Zwarg J, Hamdorf M, Welzel K, Esly N, Panitz S, Reuter A, Ramos I, Jatiani A, Mulder LC, Fernandez-Sesma A, Rutsch F, Simon V, König R, Flory E: SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutieres syndrome are highly susceptible to HIV-1 infection. PLoS Pathog 2011, 7:e1002425.
-
(2011)
PLoS Pathog
, vol.7
-
-
Berger, A.1
Sommer, A.F.2
Zwarg, J.3
Hamdorf, M.4
Welzel, K.5
Esly, N.6
Panitz, S.7
Reuter, A.8
Ramos, I.9
Jatiani, A.10
Mulder, L.C.11
Fernandez-Sesma, A.12
Rutsch, F.13
Simon, V.14
König, R.15
Flory, E.16
-
67
-
-
77956497003
-
A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells
-
Manel N, Hogstad B, Wang Y, Levy DE, Unutmaz D, Littman DR: A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells. Nature 2010, 467:214-217.
-
(2010)
Nature
, vol.467
, pp. 214-217
-
-
Manel, N.1
Hogstad, B.2
Wang, Y.3
Levy, D.E.4
Unutmaz, D.5
Littman, D.R.6
-
68
-
-
79959353247
-
Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon
-
Pertel T, Reinhard C, Luban J: Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon. Retrovirology 2011, 8:49.
-
(2011)
Retrovirology
, vol.8
, pp. 49
-
-
Pertel, T.1
Reinhard, C.2
Luban, J.3
-
69
-
-
84874716238
-
SAMHD1 restricts HIV-1 cell-to-cell transmission and limits immune detection in monocyte-derived dendritic cells
-
Puigdomenech I, Casartelli N, Porrot F, Schwartz O: SAMHD1 restricts HIV-1 cell-to-cell transmission and limits immune detection in monocyte-derived dendritic cells. J Virol 2013, 87:2846-2856.
-
(2013)
J Virol
, vol.87
, pp. 2846-2856
-
-
Puigdomenech, I.1
Casartelli, N.2
Porrot, F.3
Schwartz, O.4
-
70
-
-
84882896267
-
Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses
-
Gao D, Wu J, Wu YT, Du F, Aroh C, Yan N, Sun L, Chen ZJ: Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses. Science 2013, 341:903-906.
-
(2013)
Science
, vol.341
, pp. 903-906
-
-
Gao, D.1
Wu, J.2
Wu, Y.T.3
Du, F.4
Aroh, C.5
Yan, N.6
Sun, L.7
Chen, Z.J.8
-
71
-
-
84869170593
-
SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells
-
Baldauf HM, Pan X, Erikson E, Schmidt S, Daddacha W, Burggraf M, Schenkova K, Ambiel I, Wabnitz G, Gramberg T, Panitz S, Flory E, Landau NR, Sertel S, Rutsch F, Lasitschka F, Kim B, König R, Fackler OT, Keppler OT: SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells. Nat Med 2012, 18:1682-1689.
-
(2012)
Nat Med
, vol.18
, pp. 1682-1689
-
-
Baldauf, H.M.1
Pan, X.2
Erikson, E.3
Schmidt, S.4
Daddacha, W.5
Burggraf, M.6
Schenkova, K.7
Ambiel, I.8
Wabnitz, G.9
Gramberg, T.10
Panitz, S.11
Flory, E.12
Landau, N.R.13
Sertel, S.14
Rutsch, F.15
Lasitschka, F.16
Kim, B.17
König, R.18
Fackler, O.T.19
Keppler, O.T.20
more..
-
72
-
-
84874959500
-
Nuclease Activity of the Human SAMHD1 Protein Implicated in the Aicardi-Goutieres Syndrome and HIV-1 Restriction
-
Beloglazova N, Flick R, Tchigvintsev A, Brown G, Popovic A, Nocek B, Yakunin AF: Nuclease Activity of the Human SAMHD1 Protein Implicated in the Aicardi-Goutieres Syndrome and HIV-1 Restriction. J Biol Chem 2013, 288:8101-8110.
-
(2013)
J Biol Chem
, vol.288
, pp. 8101-8110
-
-
Beloglazova, N.1
Flick, R.2
Tchigvintsev, A.3
Brown, G.4
Popovic, A.5
Nocek, B.6
Yakunin, A.F.7
-
73
-
-
84867672682
-
SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4+ T-cells
-
Descours B, Cribier A, Chable-Bessia C, Ayinde D, Rice G, Crow Y, Yatim A, Schwartz O, Laguette N, Benkirane M: SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4+ T-cells. Retrovirology 2012, 9:87.
-
(2012)
Retrovirology
, vol.9
, pp. 87
-
-
Descours, B.1
Cribier, A.2
Chable-Bessia, C.3
Ayinde, D.4
Rice, G.5
Crow, Y.6
Yatim, A.7
Schwartz, O.8
Laguette, N.9
Benkirane, M.10
-
74
-
-
83555164881
-
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
-
Goldstone DC, Ennis-Adeniran V, Hedden JJ, Groom HC, Rice GI, Christodoulou E, Walker PA, Kelly G, Haire LF, Yap MW, de Carvalho LP, Stoye JP, Crow YJ, Taylor IA, Webb M: HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase. Nature 2011, 480:379-382.
-
(2011)
Nature
, vol.480
, pp. 379-382
-
-
Goldstone, D.C.1
Ennis-Adeniran, V.2
Hedden, J.J.3
Groom, H.C.4
Rice, G.I.5
Christodoulou, E.6
Walker, P.A.7
Kelly, G.8
Haire, L.F.9
Yap, M.W.10
Carvalho, L.P.11
Stoye, J.P.12
Crow, Y.J.13
Taylor, I.A.14
Webb, M.15
-
75
-
-
84862777555
-
SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
-
Lahouassa H, Daddacha W, Hofmann H, Ayinde D, Logue EC, Dragin L, Bloch N, Maudet C, Bertrand M, Gramberg T, Pancino G, Priet S, Canard B, Laguette N, Benkirane M, Transy C, Landau NR, Kim B, Margottin-Goguet F: SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates. Nat Immunol 2012, 13:223-228.
-
(2012)
Nat Immunol
, vol.13
, pp. 223-228
-
-
Lahouassa, H.1
Daddacha, W.2
Hofmann, H.3
Ayinde, D.4
Logue, E.C.5
Dragin, L.6
Bloch, N.7
Maudet, C.8
Bertrand, M.9
Gramberg, T.10
Pancino, G.11
Priet, S.12
Canard, B.13
Laguette, N.14
Benkirane, M.15
Transy, C.16
Landau, N.R.17
Kim, B.18
Margottin-Goguet, F.19
-
76
-
-
83755162644
-
Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase
-
Powell RD, Holland PJ, Hollis T, Perrino FW: Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase. J Biol Chem 2011, 286:43596-43600.
-
(2011)
J Biol Chem
, vol.286
, pp. 43596-43600
-
-
Powell, R.D.1
Holland, P.J.2
Hollis, T.3
Perrino, F.W.4
-
77
-
-
84905732218
-
The ribonuclease activity of SAMHD1 is required for HIV-1 restriction
-
Ryoo J, Choi J, Oh C, Kim S, Seo M, Kim SY, Seo D, Kim J, White TE, Brandariz-Nunez A, Nuñez A, Diaz-Griffero F, Yun CH, Hollenbaugh JA, Kim B, Baek D, Ahn K: The ribonuclease activity of SAMHD1 is required for HIV-1 restriction. Nat Med 2014, 20:936-941.
-
(2014)
Nat Med
, vol.20
, pp. 936-941
-
-
Ryoo, J.1
Choi, J.2
Oh, C.3
Kim, S.4
Seo, M.5
Kim, S.Y.6
Seo, D.7
Kim, J.8
White, T.E.9
Brandariz-Nunez, A.10
Nuñez, A.11
Diaz-Griffero, F.12
Yun, C.H.13
Hollenbaugh, J.A.14
Kim, B.15
Baek, D.16
Ahn, K.17
-
78
-
-
84890215093
-
The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells
-
Lahaye X, Satoh T, Gentili M, Cerboni S, Conrad C, Hurbain I, El Marjou A, Lacabaratz C, Lelievre JD, Manel N: The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells. Immunity 2013, 39:1132-1142.
-
(2013)
Immunity
, vol.39
, pp. 1132-1142
-
-
Lahaye, X.1
Satoh, T.2
Gentili, M.3
Cerboni, S.4
Conrad, C.5
Hurbain, I.6
Marjou, A.7
Lacabaratz, C.8
Lelievre, J.D.9
Manel, N.10
-
79
-
-
84888054227
-
HIV-1 evades innate immune recognition through specific cofactor recruitment
-
Rasaiyaah J, Tan CP, Fletcher AJ, Price AJ, Blondeau C, Hilditch L, Jacques DA, Selwood DL, James LC, Noursadeghi M, Towers GJ: HIV-1 evades innate immune recognition through specific cofactor recruitment. Nature 2013, 503:402-405.
-
(2013)
Nature
, vol.503
, pp. 402-405
-
-
Rasaiyaah, J.1
Tan, C.P.2
Fletcher, A.J.3
Price, A.J.4
Blondeau, C.5
Hilditch, L.6
Jacques, D.A.7
Selwood, D.L.8
James, L.C.9
Noursadeghi, M.10
Towers, G.J.11
-
80
-
-
84899769393
-
The innate immune response to HIV-1: to sense or not to sense
-
Landau NR: The innate immune response to HIV-1: to sense or not to sense. DNA Cell Biol 2014, 33:271-274.
-
(2014)
DNA Cell Biol
, vol.33
, pp. 271-274
-
-
Landau, N.R.1
-
81
-
-
34248579519
-
Out of Africa: what can we learn from HIV-2 about protective immunity to HIV-1?
-
Rowland-Jones SL, Whittle HC: Out of Africa: what can we learn from HIV-2 about protective immunity to HIV-1? Nat Immunol 2007, 8:329-331.
-
(2007)
Nat Immunol
, vol.8
, pp. 329-331
-
-
Rowland-Jones, S.L.1
Whittle, H.C.2
-
82
-
-
84899682448
-
DNA damage repair machinery and HIV escape from innate immune sensing
-
Bregnard C, Benkirane M, Laguette N: DNA damage repair machinery and HIV escape from innate immune sensing. Front Microbiol 2014, 5:176.
-
(2014)
Front Microbiol
, vol.5
, pp. 176
-
-
Bregnard, C.1
Benkirane, M.2
Laguette, N.3
-
83
-
-
84884333427
-
Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing
-
Gehrke N, Mertens C, Zillinger T, Wenzel J, Bald T, Zahn S, Tuting T, Hartmann G, Barchet W: Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing. Immunity 2013, 39:482-495.
-
(2013)
Immunity
, vol.39
, pp. 482-495
-
-
Gehrke, N.1
Mertens, C.2
Zillinger, T.3
Wenzel, J.4
Bald, T.5
Zahn, S.6
Tuting, T.7
Hartmann, G.8
Barchet, W.9
-
84
-
-
0037032428
-
Cleavage of a DNA-RNA-DNA/DNA chimeric substrate containing a single ribonucleotide at the DNA-RNA junction with prokaryotic RNases HII
-
Haruki M, Tsunaka Y, Morikawa M, Kanaya S: Cleavage of a DNA-RNA-DNA/DNA chimeric substrate containing a single ribonucleotide at the DNA-RNA junction with prokaryotic RNases HII. FEBS Lett 2002, 531:204-208.
-
(2002)
FEBS Lett
, vol.531
, pp. 204-208
-
-
Haruki, M.1
Tsunaka, Y.2
Morikawa, M.3
Kanaya, S.4
-
85
-
-
36248988008
-
Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease
-
Yang YG, Lindahl T, Barnes DE: Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease. Cell 2007, 131:873-886.
-
(2007)
Cell
, vol.131
, pp. 873-886
-
-
Yang, Y.G.1
Lindahl, T.2
Barnes, D.E.3
-
86
-
-
33746581694
-
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus
-
Crow YJ, Hayward BE, Parmar R, Robins P, Leitch A, Ali M, Black DN, van Bokhoven H, Brunner HG, Hamel BC, Corry PC, Cowan FM, Frints SG, Klepper J, Livingston JH, Lynch SA, Massey RF, Meritet JF, Michaud JL, Ponsot G, Voit T, Lebon P, Bonthron DT, Jackson AP, Barnes DE, Lindahl T: Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus. Nat Genet 2006, 38:917-920.
-
(2006)
Nat Genet
, vol.38
, pp. 917-920
-
-
Crow, Y.J.1
Hayward, B.E.2
Parmar, R.3
Robins, P.4
Leitch, A.5
Ali, M.6
Black, D.N.7
Bokhoven, H.8
Brunner, H.G.9
Hamel, B.C.10
Corry, P.C.11
Cowan, F.M.12
Frints, S.G.13
Klepper, J.14
Livingston, J.H.15
Lynch, S.A.16
Massey, R.F.17
Meritet, J.F.18
Michaud, J.L.19
Ponsot, G.20
Voit, T.21
Lebon, P.22
Bonthron, D.T.23
Jackson, A.P.24
Barnes, D.E.25
Lindahl, T.26
more..
-
87
-
-
34147185679
-
Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome
-
Rice G, Newman WG, Dean J, Patrick T, Parmar R, Flintoff K, Robins P, Harvey S, Hollis T, O'Hara A, Herrick AL, Bowden AP, Perrino FW, Lindahl T, Barnes DE, Crow YJ: Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome. Am J Hum Genet 2007, 80:811-815.
-
(2007)
Am J Hum Genet
, vol.80
, pp. 811-815
-
-
Rice, G.1
Newman, W.G.2
Dean, J.3
Patrick, T.4
Parmar, R.5
Flintoff, K.6
Robins, P.7
Harvey, S.8
Hollis, T.9
O'Hara, A.10
Herrick, A.L.11
Bowden, A.P.12
Perrino, F.W.13
Lindahl, T.14
Barnes, D.E.15
Crow, Y.J.16
-
88
-
-
35349019691
-
Clinical and molecular phenotype of Aicardi-Goutieres syndrome
-
Rice G, Patrick T, Parmar R, Taylor CF, Aeby A, Aicardi J, Artuch R, Montalto SA, Bacino CA, Barroso B, Baxter P, Benko WS, Bergmann C, Bertini E, Biancheri R, Blair EM, Blau N, Bonthron DT, Briggs T, Brueton LA, Brunner HG, Burke CJ, Carr IM, Carvalho DR, Chandler KE, Christen HJ, Corry PC, Cowan FM, Cox H, D'Arrigo S, et al: Clinical and molecular phenotype of Aicardi-Goutieres syndrome. Am J Hum Genet 2007, 81:713-725.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 713-725
-
-
Rice, G.1
Patrick, T.2
Parmar, R.3
Taylor, C.F.4
Aeby, A.5
Aicardi, J.6
Artuch, R.7
Montalto, S.A.8
Bacino, C.A.9
Barroso, B.10
Baxter, P.11
Benko, W.S.12
Bergmann, C.13
Bertini, E.14
Biancheri, R.15
Blair, E.M.16
Blau, N.17
Bonthron, D.T.18
Briggs, T.19
Brueton, L.A.20
Brunner, H.G.21
Burke, C.J.22
Carr, I.M.23
Carvalho, D.R.24
Chandler, K.E.25
Christen, H.J.26
Corry, P.C.27
Cowan, F.M.28
Cox, H.29
D'Arrigo, S.30
more..
-
89
-
-
49549100511
-
Trex1 prevents cell-intrinsic initiation of autoimmunity
-
Stetson DB, Ko JS, Heidmann T, Medzhitov R: Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 2008, 134:587-598.
-
(2008)
Cell
, vol.134
, pp. 587-598
-
-
Stetson, D.B.1
Ko, J.S.2
Heidmann, T.3
Medzhitov, R.4
-
90
-
-
33645529880
-
Dual inhibitory effects of APOBEC family proteins on retrotransposition of mammalian endogenous retroviruses
-
Esnault C, Millet J, Schwartz O, Heidmann T: Dual inhibitory effects of APOBEC family proteins on retrotransposition of mammalian endogenous retroviruses. Nucleic Acids Res 2006, 34:1522-1531.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 1522-1531
-
-
Esnault, C.1
Millet, J.2
Schwartz, O.3
Heidmann, T.4
-
91
-
-
84884590112
-
Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutieres syndrome-related SAMHD1
-
Zhao K, Du J, Han X, Goodier JL, Li P, Zhou X, Wei W, Evans SL, Li L, Zhang W, Cheung LE, Wang G, Kazazian HH Jr, Yu XF: Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutieres syndrome-related SAMHD1. Cell Rep 2013, 4:1108-1115.
-
(2013)
Cell Rep
, vol.4
, pp. 1108-1115
-
-
Zhao, K.1
Du, J.2
Han, X.3
Goodier, J.L.4
Li, P.5
Zhou, X.6
Wei, W.7
Evans, S.L.8
Li, L.9
Zhang, W.10
Cheung, L.E.11
Wang, G.12
Kazazian, H.H.13
Yu, X.F.14
-
92
-
-
84899685774
-
Safeguard against DNA sensing: the role of TREX1 in HIV-1 infection and autoimmune diseases
-
Hasan M, Yan N: Safeguard against DNA sensing: the role of TREX1 in HIV-1 infection and autoimmune diseases. Front Microbiol 2014, 5:193.
-
(2014)
Front Microbiol
, vol.5
, pp. 193
-
-
Hasan, M.1
Yan, N.2
-
93
-
-
84861376081
-
Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection
-
Ambrose Z, Lee K, Ndjomou J, Xu H, Oztop I, Matous J, Takemura T, Unutmaz D, Engelman A, Hughes SH, KewalRamani VN: Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection. J Virol 2012, 86:4708-4714.
-
(2012)
J Virol
, vol.86
, pp. 4708-4714
-
-
Ambrose, Z.1
Lee, K.2
Ndjomou, J.3
Xu, H.4
Oztop, I.5
Matous, J.6
Takemura, T.7
Unutmaz, D.8
Engelman, A.9
Hughes, S.H.10
KewalRamani, V.N.11
-
94
-
-
0034855639
-
Human immunodeficiency virus type 1N-terminal capsid mutants that exhibit aberrant core morphology and are blocked in initiation of reverse transcription in infected cells
-
Tang S, Murakami T, Agresta BE, Campbell S, Freed EO, Levin JG: Human immunodeficiency virus type 1N-terminal capsid mutants that exhibit aberrant core morphology and are blocked in initiation of reverse transcription in infected cells. J Virol 2001, 75:9357-9366.
-
(2001)
J Virol
, vol.75
, pp. 9357-9366
-
-
Tang, S.1
Murakami, T.2
Agresta, B.E.3
Campbell, S.4
Freed, E.O.5
Levin, J.G.6
-
95
-
-
84871985539
-
Inhibition of reverse transcriptase activity increases stability of the HIV-1 core
-
Yang Y, Fricke T, Diaz-Griffero F: Inhibition of reverse transcriptase activity increases stability of the HIV-1 core. J Virol 2013, 87:683-687.
-
(2013)
J Virol
, vol.87
, pp. 683-687
-
-
Yang, Y.1
Fricke, T.2
Diaz-Griffero, F.3
-
96
-
-
84892946076
-
IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV
-
Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC: IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science 2014, 343:428-432.
-
(2014)
Science
, vol.343
, pp. 428-432
-
-
Monroe, K.M.1
Yang, Z.2
Johnson, J.R.3
Geng, X.4
Doitsh, G.5
Krogan, N.J.6
Greene, W.C.7
-
97
-
-
84888002403
-
IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication
-
Jakobsen MR, Bak RO, Andersen A, Berg RK, Jensen SB, Tengchuan J, Laustsen A, Hansen K, Ostergaard L, Fitzgerald KA, Xiao TS, Mikkelsen JG, Mogensen TH, Paludan SR: IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication. Proc Natl Acad Sci U S A 2013, 110:E4571-E4580.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. E4571-E4580
-
-
Jakobsen, M.R.1
Bak, R.O.2
Andersen, A.3
Berg, R.K.4
Jensen, S.B.5
Tengchuan, J.6
Laustsen, A.7
Hansen, K.8
Ostergaard, L.9
Fitzgerald, K.A.10
Xiao, T.S.11
Mikkelsen, J.G.12
Mogensen, T.H.13
Paludan, S.R.14
-
98
-
-
84866740475
-
Evolutionary conflicts between viruses and restriction factors shape immunity
-
Duggal NK, Emerman M: Evolutionary conflicts between viruses and restriction factors shape immunity. Nat Rev Immunol 2012, 12:687-695.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 687-695
-
-
Duggal, N.K.1
Emerman, M.2
-
99
-
-
84860534449
-
Differential effects of Vpr on single-cycle and spreading HIV-1 infections in CD4+ T-cells and dendritic cells
-
de Silva S, Planelles V, Wu L: Differential effects of Vpr on single-cycle and spreading HIV-1 infections in CD4+ T-cells and dendritic cells. PLoS One 2012, 7:e35385.
-
(2012)
PLoS One
, vol.7
-
-
Silva, S.1
Planelles, V.2
Wu, L.3
|