-
1
-
-
33749535905
-
Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery
-
Epub September 10, 2006; doi: 10.1038/nature05175
-
Angers, S., Li, T., Yi, X., MacCoss, M.J., Moon, R.T., and Zheng, N. 2006. Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Nature Epub September 10, 2006; doi: 10.1038/nature05175.
-
(2006)
Nature
-
-
Angers, S.1
Li, T.2
Yi, X.3
MacCoss, M.J.4
Moon, R.T.5
Zheng, N.6
-
2
-
-
0042191755
-
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
-
Arai, T., Kasper, J.S., Skaar, J.R., Ali, S.H., Takahashi, C., and DeCaprio, J.A. 2003. Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis. Proc. Natl. Acad. Sci. 100: 9855-9860.
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 9855-9860
-
-
Arai, T.1
Kasper, J.S.2
Skaar, J.R.3
Ali, S.H.4
Takahashi, C.5
DeCaprio, J.A.6
-
3
-
-
0032529631
-
The human homologue for the Caenorhabditis elegans cul-4 gene is amplified and overexpressed in primary breast cancers
-
Chen, L.C., Manjeshwar, S., Lu, Y., Moore, D., Ljung, B.M., Kuo, W.L., Dairkee, S.H., Wernick, M., Collins, C., and Smith, H.S. 1998. The human homologue for the Caenorhabditis elegans cul-4 gene is amplified and overexpressed in primary breast cancers. Cancer Res. 58: 3677-3683.
-
(1998)
Cancer Res.
, vol.58
, pp. 3677-3683
-
-
Chen, L.C.1
Manjeshwar, S.2
Lu, Y.3
Moore, D.4
Ljung, B.M.5
Kuo, W.L.6
Dairkee, S.H.7
Wernick, M.8
Collins, C.9
Smith, H.S.10
-
4
-
-
0023803543
-
Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA
-
Chu, G. and Chang, E. 1988. Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA. Science 242: 564-567.
-
(1988)
Science
, vol.242
, pp. 564-567
-
-
Chu, G.1
Chang, E.2
-
5
-
-
0030695025
-
A complex of Cdc4p, Skp1p, and Cdc53p/Cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
-
Feldman, R.M.R., Correll, C.C., Kaplan, K.B., and Deshaies, R.J. 1997. A complex of Cdc4p, Skp1p, and Cdc53p/Cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell 91: 221-230.
-
(1997)
Cell
, vol.91
, pp. 221-230
-
-
Feldman, R.M.R.1
Correll, C.C.2
Kaplan, K.B.3
Deshaies, R.J.4
-
6
-
-
0242575197
-
Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases
-
Furukawa, M., He, Y.J., Borchers, C., and Xiong, Y. 2003. Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases. Nat. Cell Biol. 5: 1001-1007.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 1001-1007
-
-
Furukawa, M.1
He, Y.J.2
Borchers, C.3
Xiong, Y.4
-
7
-
-
0141750416
-
BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases
-
Geyer, R., Wee, S., Anderson, S., Yates, J., and Wolf, D.A. 2003. BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases. Mol. Cell 12: 783-790.
-
(2003)
Mol. Cell
, vol.12
, pp. 783-790
-
-
Geyer, R.1
Wee, S.2
Anderson, S.3
Yates, J.4
Wolf, D.A.5
-
8
-
-
8344251662
-
Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases
-
Goldenberg, S.J., Cascio, T.C., Shumway, S.D., Garbutt, K.C., Liu, J., Xiong, Y., and Zheng, N. 2004. Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases. Cell 119: 517-528.
-
(2004)
Cell
, vol.119
, pp. 517-528
-
-
Goldenberg, S.J.1
Cascio, T.C.2
Shumway, S.D.3
Garbutt, K.C.4
Liu, J.5
Xiong, Y.6
Zheng, N.7
-
9
-
-
0037509859
-
The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage
-
Groisman, R., Polanowska, J., Kuraoka, I., Sawada, J., Saijo, M., Drapkin, R., Kisselev, A.F., Tanaka, K., and Nakatani, Y. 2003. The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. Cell 113: 357-367.
-
(2003)
Cell
, vol.113
, pp. 357-367
-
-
Groisman, R.1
Polanowska, J.2
Kuraoka, I.3
Sawada, J.4
Saijo, M.5
Drapkin, R.6
Kisselev, A.F.7
Tanaka, K.8
Nakatani, Y.9
-
11
-
-
0030457014
-
Ubiquitin-dependent protein degradation
-
Hochstrasser, M. 1996. Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30: 405-439.
-
(1996)
Annu. Rev. Genet.
, vol.30
, pp. 405-439
-
-
Hochstrasser, M.1
-
12
-
-
17044378618
-
Ddb1 controls genome stability and meiosis in fission yeast
-
Holmberg, C., Fleck, O., Hansen, H.A., Liu, C., Slaaby, R., Carr, A.M., and Nielsen, O. 2005. Ddb1 controls genome stability and meiosis in fission yeast. Genes & Dev. 19: 853-862.
-
(2005)
Genes & Dev.
, vol.19
, pp. 853-862
-
-
Holmberg, C.1
Fleck, O.2
Hansen, H.A.3
Liu, C.4
Slaaby, R.5
Carr, A.M.6
Nielsen, O.7
-
13
-
-
5444274523
-
Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage
-
Hu, J., McCall, C.M., Ohta, T., and Xiong, Y. 2004. Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage. Nat. Cell Biol. 6: 1003-1009.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 1003-1009
-
-
Hu, J.1
McCall, C.M.2
Ohta, T.3
Xiong, Y.4
-
14
-
-
0034308251
-
The lore of the RINGs: Substrate recognition and catalysis by ubiquitin ligases
-
Jackson, P., Eldridge, A.G., Freed, E., Furstenthal, L., Hsu, J.Y., Kaiser, B.K., and Reimann, J.D.R. 2000. The lore of the RINGs: Substrate recognition and catalysis by ubiquitin ligases. Trends Cell Biol. 10: 429-439.
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 429-439
-
-
Jackson, P.1
Eldridge, A.G.2
Freed, E.3
Furstenthal, L.4
Hsu, J.Y.5
Kaiser, B.K.6
Reimann, J.D.R.7
-
15
-
-
0032535364
-
The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families
-
Kamura, T., Sato, S., Haque, D., Liu, L., Kaelin Jr., W.G., Conaway, R.C., and Conaway, J.W. 1998. The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families. Genes & Dev. 12: 3872-3881.
-
(1998)
Genes & Dev.
, vol.12
, pp. 3872-3881
-
-
Kamura, T.1
Sato, S.2
Haque, D.3
Liu, L.4
Kaelin Jr., W.G.5
Conaway, R.C.6
Conaway, J.W.7
-
16
-
-
33747873322
-
A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1
-
Jin, J., Arias, E.E., Chen, J., Harper, J.W., and Walter, J.C. 2006. A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. Mol. Cell 23: 709-721.
-
(2006)
Mol. Cell
, vol.23
, pp. 709-721
-
-
Jin, J.1
Arias, E.E.2
Chen, J.3
Harper, J.W.4
Walter, J.C.5
-
17
-
-
0035839577
-
Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase
-
Kamura, T., Burian, D., Yan, Q., Schmidt, S.L., Lane, W.S., Querido, E., Branton, P.E., Shilatifard, A., Conaway, R.C., and Conaway, J.W. 2001. Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase. J. Biol. Chem. 276: 29748-29753.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 29748-29753
-
-
Kamura, T.1
Burian, D.2
Yan, Q.3
Schmidt, S.L.4
Lane, W.S.5
Querido, E.6
Branton, P.E.7
Shilatifard, A.8
Conaway, R.C.9
Conaway, J.W.10
-
18
-
-
10644276385
-
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases
-
Kamura, T., Maenaka, K., Kotoshiba, S., Matsumoto, M., Kohda, D., Conaway, R.C., Conaway, J.W., and Nakayama, K.I. 2004. VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases. Genes & Dev. 18: 3055-3065.
-
(2004)
Genes & Dev.
, vol.18
, pp. 3055-3065
-
-
Kamura, T.1
Maenaka, K.2
Kotoshiba, S.3
Matsumoto, M.4
Kohda, D.5
Conaway, R.C.6
Conaway, J.W.7
Nakayama, K.I.8
-
19
-
-
0029807944
-
How proteolysis drives the cell cycle
-
King, R.W., Deshaies, R.J., Peters, J.-M., and Kirschner, M.W. 1996. How proteolysis drives the cell cycle. Science 274: 1652-1659.
-
(1996)
Science
, vol.274
, pp. 1652-1659
-
-
King, R.W.1
Deshaies, R.J.2
Peters, J.-M.3
Kirschner, M.W.4
-
20
-
-
30344460705
-
Structure of DDB1 in complex with a paramyxovirus V protein: Viral hijack of a propeller cluster in ubiquitin ligase
-
Li, T., Chen, X., Garbutt, K.C., Zhou, P., and Zheng, N. 2006. Structure of DDB1 in complex with a paramyxovirus V protein: Viral hijack of a propeller cluster in ubiquitin ligase. Cell 124: 105-117.
-
(2006)
Cell
, vol.124
, pp. 105-117
-
-
Li, T.1
Chen, X.2
Garbutt, K.C.3
Zhou, P.4
Zheng, N.5
-
21
-
-
0036929129
-
NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases
-
Liu, J., Furukawa, M., Matsumoto, T., and Xiong, Y. 2002. NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases. Mol. Cell 10: 1511-1518.
-
(2002)
Mol. Cell
, vol.10
, pp. 1511-1518
-
-
Liu, J.1
Furukawa, M.2
Matsumoto, T.3
Xiong, Y.4
-
22
-
-
27844432597
-
Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase
-
Liu, C., Poitelea, M., Watson, A., Yoshida, S.H., Shimoda, C., Holmberg, C., Nielsen, O., and Carr, A.M. 2005. Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase. EMBO J. 24: 3940-3951.
-
(2005)
EMBO J.
, vol.24
, pp. 3940-3951
-
-
Liu, C.1
Poitelea, M.2
Watson, A.3
Yoshida, S.H.4
Shimoda, C.5
Holmberg, C.6
Nielsen, O.7
Carr, A.M.8
-
23
-
-
0031846022
-
Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A
-
Michel, J.J. and Xiong, Y. 1998. Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A. Cell Growth Differ. 9: 435-449.
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 435-449
-
-
Michel, J.J.1
Xiong, Y.2
-
24
-
-
0034666340
-
PSI-BLAST searches using hidden markov models of structural repeats: Prediction of an unusual sliding DNA clamp and of -propellers in UV- damaged DNA-binding protein
-
Neuwald, A.F. and Poleksic, A. 2000. PSI-BLAST searches using hidden markov models of structural repeats: Prediction of an unusual sliding DNA clamp and of -propellers in UV- damaged DNA-binding protein. Nucleic Acids Res. 28: 3570-3580.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 3570-3580
-
-
Neuwald, A.F.1
Poleksic, A.2
-
25
-
-
0033120027
-
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity
-
Ohta, T., Michel, J.J., Schottelius, A.J., and Xiong, Y. 1999. ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol. Cell 3: 535-541.
-
(1999)
Mol. Cell
, vol.3
, pp. 535-541
-
-
Ohta, T.1
Michel, J.J.2
Schottelius, A.J.3
Xiong, Y.4
-
26
-
-
11244351579
-
Function and regulation of cullin-RING ubiquitin ligases
-
Petroski, M.D. and Deshaies, R.J. 2005. Function and regulation of cullin-RING ubiquitin ligases. Nat. Rev. Mol. Cell Biol. 6: 9-20.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 9-20
-
-
Petroski, M.D.1
Deshaies, R.J.2
-
27
-
-
0141493448
-
The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase
-
Pintard, L., Willis, J.H., Willems, A., Johnson, J.L., Srayko, M., Kurz, T., Glaser, S., Mains, P.E., Tyers, M., Bowerman, B., et al. 2003. The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase. Nature 425: 311-316.
-
(2003)
Nature
, vol.425
, pp. 311-316
-
-
Pintard, L.1
Willis, J.H.2
Willems, A.3
Johnson, J.L.4
Srayko, M.5
Kurz, T.6
Glaser, S.7
Mains, P.E.8
Tyers, M.9
Bowerman, B.10
-
28
-
-
0038105065
-
True XP group E patients have a defective UV-damaged DNA binding protein complex and mutations in DDB2 which reveal the functional domains of its p48 product
-
Rapic-Otrin, V., Navazza, V., Nardo, T., Botta, E., McLenigan, M., Bisi, D.C., Levine, A.S., and Stefanini, M. 2003. True XP group E patients have a defective UV-damaged DNA binding protein complex and mutations in DDB2 which reveal the functional domains of its p48 product. Hum. Mol. Genet. 12: 1507-1522.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 1507-1522
-
-
Rapic-Otrin, V.1
Navazza, V.2
Nardo, T.3
Botta, E.4
McLenigan, M.5
Bisi, D.C.6
Levine, A.S.7
Stefanini, M.8
-
29
-
-
0030662523
-
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
-
Skowyra, D., Craig, K., Tyers, M., Elledge, S.J., and Harper, J.W. 1997. F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91: 209-219.
-
(1997)
Cell
, vol.91
, pp. 209-219
-
-
Skowyra, D.1
Craig, K.2
Tyers, M.3
Elledge, S.J.4
Harper, J.W.5
-
30
-
-
0030034646
-
Crystal structure of a G-protein βγ dimer at 2.1A resolution
-
Sondek, J., Bohm, A., Lambright, D.G., Hamm, H.E., and Sigler, P.B. 1996. Crystal structure of a G-protein βγ dimer at 2.1A resolution. Nature 379: 369-374.
-
(1996)
Nature
, vol.379
, pp. 369-374
-
-
Sondek, J.1
Bohm, A.2
Lambright, D.G.3
Hamm, H.E.4
Sigler, P.B.5
-
31
-
-
0033574737
-
Structure of the VHL-ElonginC-ElonginB complex: Implications for VHL tumor suppressor function
-
Stebbins, C.E., Kaelin Jr., W.G., and Pavletich, N.P. 1999. Structure of the VHL-ElonginC-ElonginB complex: Implications for VHL tumor suppressor function. Science 284: 455-461.
-
(1999)
Science
, vol.284
, pp. 455-461
-
-
Stebbins, C.E.1
Kaelin Jr., W.G.2
Pavletich, N.P.3
-
32
-
-
1342275414
-
Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase
-
Wertz, I.E., O'Rourke, K.M., Zhang, Z., Dornan, D., Arnott, D., Deshaies, R.J., and Dixit, V.M. 2004. Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase. Science 303: 1371-1374.
-
(2004)
Science
, vol.303
, pp. 1371-1374
-
-
Wertz, I.E.1
O'Rourke, K.M.2
Zhang, Z.3
Dornan, D.4
Arnott, D.5
Deshaies, R.J.6
Dixit, V.M.7
-
33
-
-
0141493447
-
BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3
-
Xu, L., Wei, Y., Reboul, J., Vaglio, P., Shin, T.H., Vidal, M., Elledge, S.J., and Harper, J.W. 2003. BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3. Nature 425: 316-321.
-
(2003)
Nature
, vol.425
, pp. 316-321
-
-
Xu, L.1
Wei, Y.2
Reboul, J.3
Vaglio, P.4
Shin, T.H.5
Vidal, M.6
Elledge, S.J.7
Harper, J.W.8
-
34
-
-
13044263097
-
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation
-
Zhang, J.G., Farley, A., Nicholson, S.E., Willson, T.A., Zugaro, L.M., Simpson, R.J., Moritz, R.L., Cary, D., Richardson, R., Hausmann, G., et al. 1999. The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation. Proc. Natl. Acad. Sci. 96: 2071-2076.
-
(1999)
Proc. Natl. Acad. Sci.
, vol.96
, pp. 2071-2076
-
-
Zhang, J.G.1
Farley, A.2
Nicholson, S.E.3
Willson, T.A.4
Zugaro, L.M.5
Simpson, R.J.6
Moritz, R.L.7
Cary, D.8
Richardson, R.9
Hausmann, G.10
-
35
-
-
0036924046
-
CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex
-
Zheng, J., Yang, X., Harrell, J.M., Ryzhikov, S., Shim, E.H., Lykke-Andersen, K., Wei, N., Sun, H., Kobayashi, R., and Zhang, H. 2002. CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex. Mol. Cell 10: 1519-1526.
-
(2002)
Mol. Cell
, vol.10
, pp. 1519-1526
-
-
Zheng, J.1
Yang, X.2
Harrell, J.M.3
Ryzhikov, S.4
Shim, E.H.5
Lykke-Andersen, K.6
Wei, N.7
Sun, H.8
Kobayashi, R.9
Zhang, H.10
-
36
-
-
18344391432
-
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex
-
Zheng, N., Schulman, B.A., Song, L., Miller, J.J., Jeffrey, P.D., Wang, P., Chu, C., Koepp, D.M., Elledge, S.J., Pagano, M., et al. 2002. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature 416: 703-709.
-
(2002)
Nature
, vol.416
, pp. 703-709
-
-
Zheng, N.1
Schulman, B.A.2
Song, L.3
Miller, J.J.4
Jeffrey, P.D.5
Wang, P.6
Chu, C.7
Koepp, D.M.8
Elledge, S.J.9
Pagano, M.10
|