메뉴 건너뛰기




Volumn 20, Issue 21, 2006, Pages 2949-2954

DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases

Author keywords

CUL4; Cullin; DDB1; DWD; Ubiquitin; WD40

Indexed keywords

CELL PROTEIN; CULLIN; CULLIN 4; DNA BINDING PROTEIN; DNA BINDING PROTEIN 1; PROTEIN DWD; PROTEIN ROC1; PROTEIN WD40; REGULATOR PROTEIN; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

EID: 33751112293     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1483206     Document Type: Article
Times cited : (280)

References (36)
  • 1
    • 33749535905 scopus 로고    scopus 로고
    • Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery
    • Epub September 10, 2006; doi: 10.1038/nature05175
    • Angers, S., Li, T., Yi, X., MacCoss, M.J., Moon, R.T., and Zheng, N. 2006. Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Nature Epub September 10, 2006; doi: 10.1038/nature05175.
    • (2006) Nature
    • Angers, S.1    Li, T.2    Yi, X.3    MacCoss, M.J.4    Moon, R.T.5    Zheng, N.6
  • 4
    • 0023803543 scopus 로고
    • Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA
    • Chu, G. and Chang, E. 1988. Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA. Science 242: 564-567.
    • (1988) Science , vol.242 , pp. 564-567
    • Chu, G.1    Chang, E.2
  • 5
    • 0030695025 scopus 로고    scopus 로고
    • A complex of Cdc4p, Skp1p, and Cdc53p/Cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
    • Feldman, R.M.R., Correll, C.C., Kaplan, K.B., and Deshaies, R.J. 1997. A complex of Cdc4p, Skp1p, and Cdc53p/Cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell 91: 221-230.
    • (1997) Cell , vol.91 , pp. 221-230
    • Feldman, R.M.R.1    Correll, C.C.2    Kaplan, K.B.3    Deshaies, R.J.4
  • 6
    • 0242575197 scopus 로고    scopus 로고
    • Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases
    • Furukawa, M., He, Y.J., Borchers, C., and Xiong, Y. 2003. Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases. Nat. Cell Biol. 5: 1001-1007.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 1001-1007
    • Furukawa, M.1    He, Y.J.2    Borchers, C.3    Xiong, Y.4
  • 7
    • 0141750416 scopus 로고    scopus 로고
    • BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases
    • Geyer, R., Wee, S., Anderson, S., Yates, J., and Wolf, D.A. 2003. BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases. Mol. Cell 12: 783-790.
    • (2003) Mol. Cell , vol.12 , pp. 783-790
    • Geyer, R.1    Wee, S.2    Anderson, S.3    Yates, J.4    Wolf, D.A.5
  • 8
    • 8344251662 scopus 로고    scopus 로고
    • Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases
    • Goldenberg, S.J., Cascio, T.C., Shumway, S.D., Garbutt, K.C., Liu, J., Xiong, Y., and Zheng, N. 2004. Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases. Cell 119: 517-528.
    • (2004) Cell , vol.119 , pp. 517-528
    • Goldenberg, S.J.1    Cascio, T.C.2    Shumway, S.D.3    Garbutt, K.C.4    Liu, J.5    Xiong, Y.6    Zheng, N.7
  • 9
    • 0037509859 scopus 로고    scopus 로고
    • The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage
    • Groisman, R., Polanowska, J., Kuraoka, I., Sawada, J., Saijo, M., Drapkin, R., Kisselev, A.F., Tanaka, K., and Nakatani, Y. 2003. The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. Cell 113: 357-367.
    • (2003) Cell , vol.113 , pp. 357-367
    • Groisman, R.1    Polanowska, J.2    Kuraoka, I.3    Sawada, J.4    Saijo, M.5    Drapkin, R.6    Kisselev, A.F.7    Tanaka, K.8    Nakatani, Y.9
  • 11
    • 0030457014 scopus 로고    scopus 로고
    • Ubiquitin-dependent protein degradation
    • Hochstrasser, M. 1996. Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30: 405-439.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 405-439
    • Hochstrasser, M.1
  • 13
    • 5444274523 scopus 로고    scopus 로고
    • Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage
    • Hu, J., McCall, C.M., Ohta, T., and Xiong, Y. 2004. Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage. Nat. Cell Biol. 6: 1003-1009.
    • (2004) Nat. Cell Biol. , vol.6 , pp. 1003-1009
    • Hu, J.1    McCall, C.M.2    Ohta, T.3    Xiong, Y.4
  • 15
    • 0032535364 scopus 로고    scopus 로고
    • The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families
    • Kamura, T., Sato, S., Haque, D., Liu, L., Kaelin Jr., W.G., Conaway, R.C., and Conaway, J.W. 1998. The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families. Genes & Dev. 12: 3872-3881.
    • (1998) Genes & Dev. , vol.12 , pp. 3872-3881
    • Kamura, T.1    Sato, S.2    Haque, D.3    Liu, L.4    Kaelin Jr., W.G.5    Conaway, R.C.6    Conaway, J.W.7
  • 16
    • 33747873322 scopus 로고    scopus 로고
    • A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1
    • Jin, J., Arias, E.E., Chen, J., Harper, J.W., and Walter, J.C. 2006. A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. Mol. Cell 23: 709-721.
    • (2006) Mol. Cell , vol.23 , pp. 709-721
    • Jin, J.1    Arias, E.E.2    Chen, J.3    Harper, J.W.4    Walter, J.C.5
  • 18
    • 10644276385 scopus 로고    scopus 로고
    • VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases
    • Kamura, T., Maenaka, K., Kotoshiba, S., Matsumoto, M., Kohda, D., Conaway, R.C., Conaway, J.W., and Nakayama, K.I. 2004. VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases. Genes & Dev. 18: 3055-3065.
    • (2004) Genes & Dev. , vol.18 , pp. 3055-3065
    • Kamura, T.1    Maenaka, K.2    Kotoshiba, S.3    Matsumoto, M.4    Kohda, D.5    Conaway, R.C.6    Conaway, J.W.7    Nakayama, K.I.8
  • 20
    • 30344460705 scopus 로고    scopus 로고
    • Structure of DDB1 in complex with a paramyxovirus V protein: Viral hijack of a propeller cluster in ubiquitin ligase
    • Li, T., Chen, X., Garbutt, K.C., Zhou, P., and Zheng, N. 2006. Structure of DDB1 in complex with a paramyxovirus V protein: Viral hijack of a propeller cluster in ubiquitin ligase. Cell 124: 105-117.
    • (2006) Cell , vol.124 , pp. 105-117
    • Li, T.1    Chen, X.2    Garbutt, K.C.3    Zhou, P.4    Zheng, N.5
  • 21
    • 0036929129 scopus 로고    scopus 로고
    • NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases
    • Liu, J., Furukawa, M., Matsumoto, T., and Xiong, Y. 2002. NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases. Mol. Cell 10: 1511-1518.
    • (2002) Mol. Cell , vol.10 , pp. 1511-1518
    • Liu, J.1    Furukawa, M.2    Matsumoto, T.3    Xiong, Y.4
  • 22
    • 27844432597 scopus 로고    scopus 로고
    • Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase
    • Liu, C., Poitelea, M., Watson, A., Yoshida, S.H., Shimoda, C., Holmberg, C., Nielsen, O., and Carr, A.M. 2005. Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase. EMBO J. 24: 3940-3951.
    • (2005) EMBO J. , vol.24 , pp. 3940-3951
    • Liu, C.1    Poitelea, M.2    Watson, A.3    Yoshida, S.H.4    Shimoda, C.5    Holmberg, C.6    Nielsen, O.7    Carr, A.M.8
  • 23
    • 0031846022 scopus 로고    scopus 로고
    • Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A
    • Michel, J.J. and Xiong, Y. 1998. Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A. Cell Growth Differ. 9: 435-449.
    • (1998) Cell Growth Differ. , vol.9 , pp. 435-449
    • Michel, J.J.1    Xiong, Y.2
  • 24
    • 0034666340 scopus 로고    scopus 로고
    • PSI-BLAST searches using hidden markov models of structural repeats: Prediction of an unusual sliding DNA clamp and of -propellers in UV- damaged DNA-binding protein
    • Neuwald, A.F. and Poleksic, A. 2000. PSI-BLAST searches using hidden markov models of structural repeats: Prediction of an unusual sliding DNA clamp and of -propellers in UV- damaged DNA-binding protein. Nucleic Acids Res. 28: 3570-3580.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 3570-3580
    • Neuwald, A.F.1    Poleksic, A.2
  • 25
    • 0033120027 scopus 로고    scopus 로고
    • ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity
    • Ohta, T., Michel, J.J., Schottelius, A.J., and Xiong, Y. 1999. ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol. Cell 3: 535-541.
    • (1999) Mol. Cell , vol.3 , pp. 535-541
    • Ohta, T.1    Michel, J.J.2    Schottelius, A.J.3    Xiong, Y.4
  • 26
    • 11244351579 scopus 로고    scopus 로고
    • Function and regulation of cullin-RING ubiquitin ligases
    • Petroski, M.D. and Deshaies, R.J. 2005. Function and regulation of cullin-RING ubiquitin ligases. Nat. Rev. Mol. Cell Biol. 6: 9-20.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 9-20
    • Petroski, M.D.1    Deshaies, R.J.2
  • 28
    • 0038105065 scopus 로고    scopus 로고
    • True XP group E patients have a defective UV-damaged DNA binding protein complex and mutations in DDB2 which reveal the functional domains of its p48 product
    • Rapic-Otrin, V., Navazza, V., Nardo, T., Botta, E., McLenigan, M., Bisi, D.C., Levine, A.S., and Stefanini, M. 2003. True XP group E patients have a defective UV-damaged DNA binding protein complex and mutations in DDB2 which reveal the functional domains of its p48 product. Hum. Mol. Genet. 12: 1507-1522.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1507-1522
    • Rapic-Otrin, V.1    Navazza, V.2    Nardo, T.3    Botta, E.4    McLenigan, M.5    Bisi, D.C.6    Levine, A.S.7    Stefanini, M.8
  • 29
    • 0030662523 scopus 로고    scopus 로고
    • F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
    • Skowyra, D., Craig, K., Tyers, M., Elledge, S.J., and Harper, J.W. 1997. F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91: 209-219.
    • (1997) Cell , vol.91 , pp. 209-219
    • Skowyra, D.1    Craig, K.2    Tyers, M.3    Elledge, S.J.4    Harper, J.W.5
  • 30
    • 0030034646 scopus 로고    scopus 로고
    • Crystal structure of a G-protein βγ dimer at 2.1A resolution
    • Sondek, J., Bohm, A., Lambright, D.G., Hamm, H.E., and Sigler, P.B. 1996. Crystal structure of a G-protein βγ dimer at 2.1A resolution. Nature 379: 369-374.
    • (1996) Nature , vol.379 , pp. 369-374
    • Sondek, J.1    Bohm, A.2    Lambright, D.G.3    Hamm, H.E.4    Sigler, P.B.5
  • 31
    • 0033574737 scopus 로고    scopus 로고
    • Structure of the VHL-ElonginC-ElonginB complex: Implications for VHL tumor suppressor function
    • Stebbins, C.E., Kaelin Jr., W.G., and Pavletich, N.P. 1999. Structure of the VHL-ElonginC-ElonginB complex: Implications for VHL tumor suppressor function. Science 284: 455-461.
    • (1999) Science , vol.284 , pp. 455-461
    • Stebbins, C.E.1    Kaelin Jr., W.G.2    Pavletich, N.P.3
  • 33
    • 0141493447 scopus 로고    scopus 로고
    • BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3
    • Xu, L., Wei, Y., Reboul, J., Vaglio, P., Shin, T.H., Vidal, M., Elledge, S.J., and Harper, J.W. 2003. BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3. Nature 425: 316-321.
    • (2003) Nature , vol.425 , pp. 316-321
    • Xu, L.1    Wei, Y.2    Reboul, J.3    Vaglio, P.4    Shin, T.H.5    Vidal, M.6    Elledge, S.J.7    Harper, J.W.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.