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Volumn 41, Issue 19, 2013, Pages 8943-8958

Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE; PROTEIN MMS4; PROTEIN MUS81; UNCLASSIFIED DRUG;

EID: 84885968281     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt645     Document Type: Article
Times cited : (29)

References (79)
  • 1
    • 41149094512 scopus 로고    scopus 로고
    • Regulation of DNA repair throughout the cell cycle
    • Branzei, D. and Foiani, M. (2008) Regulation of DNA repair throughout the cell cycle. Nat. Rev. Mol. Cell. Biol., 9, 297-308.
    • (2008) Nat. Rev. Mol. Cell. Biol. , vol.9 , pp. 297-308
    • Branzei, D.1    Foiani, M.2
  • 3
    • 70350103981 scopus 로고    scopus 로고
    • The S-phase checkpoint: Targeting the replication fork
    • Segurado, M. and Tercero, J.A. (2009) The S-phase checkpoint: targeting the replication fork. Biol. Cell, 101, 617-627.
    • (2009) Biol. Cell , vol.101 , pp. 617-627
    • Segurado, M.1    Tercero, J.A.2
  • 4
    • 68249102864 scopus 로고    scopus 로고
    • DNA replication as a target of the DNA damage checkpoint
    • Zegerman, P. and Diffley, J.F. (2009) DNA replication as a target of the DNA damage checkpoint. DNA Repair (Amst.), 8, 1077-1088.
    • (2009) DNA Repair (Amst.) , vol.8 , pp. 1077-1088
    • Zegerman, P.1    Diffley, J.F.2
  • 5
    • 39449096135 scopus 로고    scopus 로고
    • Genome instability: A mechanistic view of its causes and consequences
    • Aguilera, A. and Gómez-González, B. (2008) Genome instability: a mechanistic view of its causes and consequences. Nat. Rev. Genet., 9, 204-217.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 204-217
    • Aguilera, A.1    Gómez-González, B.2
  • 7
    • 32344447374 scopus 로고    scopus 로고
    • Structure-specific DNA nucleases: Structural basis for 3D-scissors
    • Nishino, T., Ishino, Y. and Morikawa, K. (2006) Structure-specific DNA nucleases: structural basis for 3D-scissors. Curr. Opin. Struct. Biol., 16, 60-67.
    • (2006) Curr. Opin. Struct. Biol. , vol.16 , pp. 60-67
    • Nishino, T.1    Ishino, Y.2    Morikawa, K.3
  • 8
    • 50649091874 scopus 로고    scopus 로고
    • Structural and functional relationships of the XPF/MUS81 family of proteins
    • Ciccia, A., McDonald, N. and West, S.C. (2008) Structural and functional relationships of the XPF/MUS81 family of proteins. Annu. Rev. Biochem., 77, 259-287.
    • (2008) Annu. Rev. Biochem. , vol.77 , pp. 259-287
    • Ciccia, A.1    McDonald, N.2    West, S.C.3
  • 9
    • 79955522790 scopus 로고    scopus 로고
    • Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes
    • Schwartz, E.K. and Heyer, W.D. (2011) Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes. Chromosoma, 120, 109-127.
    • (2011) Chromosoma , vol.120 , pp. 109-127
    • Schwartz, E.K.1    Heyer, W.D.2
  • 10
    • 67649636091 scopus 로고    scopus 로고
    • Control of genome stability by SLX protein complexes
    • Rouse, J. (2009) Control of genome stability by SLX protein complexes. Biochem. Soc. Trans., 37, 495-510.
    • (2009) Biochem. Soc. Trans. , vol.37 , pp. 495-510
    • Rouse, J.1
  • 11
    • 34249942213 scopus 로고    scopus 로고
    • Exploring the roles of Mus81- Eme1/Mms4 at perturbed replication forks
    • Osman, F. and Whitby, M.C. (2007) Exploring the roles of Mus81- Eme1/Mms4 at perturbed replication forks. DNA Repair (Amst.), 6, 1004-1017.
    • (2007) DNA Repair (Amst.) , vol.6 , pp. 1004-1017
    • Osman, F.1    Whitby, M.C.2
  • 12
    • 0031941079 scopus 로고    scopus 로고
    • Mms4, a putative transcriptional (co) activator, protects Saccharomyces cerevisiae cells from endogenous and environmental DNA damage
    • Xiao, W., Chow, B.L. and Milo, C.N. (1998) Mms4, a putative transcriptional (co) activator, protects Saccharomyces cerevisiae cells from endogenous and environmental DNA damage. Mol. Gen. Genet., 257, 614-623.
    • (1998) Mol. Gen. Genet. , vol.257 , pp. 614-623
    • Xiao, W.1    Chow, B.L.2    Milo, C.N.3
  • 14
    • 0033830809 scopus 로고    scopus 로고
    • MUS81 encodes a novel Helix-hairpin-Helix protein involved in the response to UV- and methylation-induced DNA damage in Saccharomyces cerevisiae
    • Interthal, H. and Heyer, H.D. (2000) MUS81 encodes a novel Helix-hairpin-Helix protein involved in the response to UV- and methylation-induced DNA damage in Saccharomyces cerevisiae. Mol. Gen. Genet., 263, 812-827.
    • (2000) Mol. Gen. Genet. , vol.263 , pp. 812-827
    • Interthal, H.1    Heyer, H.D.2
  • 15
    • 0037031837 scopus 로고    scopus 로고
    • Mus81- Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks
    • Doe, C.L., Ahn, J.S., Dixon, J. and Whitby, M.C. (2002) Mus81- Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks. J. Biol. Chem., 277, 32753-32759.
    • (2002) J. Biol. Chem. , vol.277 , pp. 32753-32759
    • Doe, C.L.1    Ahn, J.S.2    Dixon, J.3    Whitby, M.C.4
  • 16
    • 0037965787 scopus 로고    scopus 로고
    • The mechanism of Mus81-Mms4 cleavage site selection distinguishes it from the homologous endonuclease Rad1-Rad10
    • Bastin-Shanower, S.A., Fricke, W.M., Mullen, J.R. and Brill, S.J. (2003) The mechanism of Mus81-Mms4 cleavage site selection distinguishes it from the homologous endonuclease Rad1-Rad10. Mol. Cell. Biol., 23, 3487-3496.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 3487-3496
    • Bastin-Shanower, S.A.1    Fricke, W.M.2    Mullen, J.R.3    Brill, S.J.4
  • 17
    • 17444416489 scopus 로고    scopus 로고
    • Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress
    • Kai, M., Boddy, M.N., Russell, P. and Wang, T.S. (2005) Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress. Genes Dev., 19, 919-932.
    • (2005) Genes Dev. , vol.19 , pp. 919-932
    • Kai, M.1    Boddy, M.N.2    Russell, P.3    Wang, T.S.4
  • 20
    • 23844468833 scopus 로고    scopus 로고
    • Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis
    • Dendouga, N., Gao, H., Moechars, D., Janicot, M., Vialard, J. and McGowan, C.H. (2005) Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis. Mol. Cell. Biol., 25, 7569-7579.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 7569-7579
    • Dendouga, N.1    Gao, H.2    Moechars, D.3    Janicot, M.4    Vialard, J.5    McGowan, C.H.6
  • 21
    • 33750206776 scopus 로고    scopus 로고
    • The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks
    • Hanada, K., Budzowska, M., Modesti, M., Maas, A., Wyman, C., Essers, J. and Kanaar, R. (2006) The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks. EMBO J., 25, 4921-4932.
    • (2006) EMBO J. , vol.25 , pp. 4921-4932
    • Hanada, K.1    Budzowska, M.2    Modesti, M.3    Maas, A.4    Wyman, C.5    Essers, J.6    Kanaar, R.7
  • 22
    • 43249128930 scopus 로고    scopus 로고
    • Mus81 is essential for sister chromatid recombination at broken replication forks
    • Roseaulin, L., Yamada, Y., Tsutsui, Y., Russell, P., Iwasaki, H. and Arcangioli, B. (2008) Mus81 is essential for sister chromatid recombination at broken replication forks. EMBO J., 27, 1378-1387.
    • (2008) EMBO J. , vol.27 , pp. 1378-1387
    • Roseaulin, L.1    Yamada, Y.2    Tsutsui, Y.3    Russell, P.4    Iwasaki, H.5    Arcangioli, B.6
  • 23
    • 84861406975 scopus 로고    scopus 로고
    • Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange
    • Munoz-Galván, S., Tous, C., Blanco, M.G., Schwartz, E.K., Ehmsen, K.T., West, S.C., Heyer, W.D. and Aguilera, A. (2012) Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange. Mol. Cell. Biol., 32, 1592-1603.
    • (2012) Mol. Cell. Biol. , vol.32 , pp. 1592-1603
    • Munoz-Galván, S.1    Tous, C.2    Blanco, M.G.3    Schwartz, E.K.4    Ehmsen, K.T.5    West, S.C.6    Heyer, W.D.7    Aguilera, A.8
  • 25
    • 0035148955 scopus 로고    scopus 로고
    • Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae
    • Mullen, J.R., Kaliraman, V., Ibrahim, S.S. and Brill, S.J. (2001) Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae. Genetics, 157, 103-118.
    • (2001) Genetics , vol.157 , pp. 103-118
    • Mullen, J.R.1    Kaliraman, V.2    Ibrahim, S.S.3    Brill, S.J.4
  • 26
    • 0037168658 scopus 로고    scopus 로고
    • Alternate pathways involving Sgs1/Top3, Mus81/Mms4, and Srs2 prevent formation of toxic recombination intermediates from singlestranded gaps created by DNA replication
    • Fabre, F., Chan, A., Heyer, W.D. and Gangloff, S. (2002) Alternate pathways involving Sgs1/Top3, Mus81/Mms4, and Srs2 prevent formation of toxic recombination intermediates from singlestranded gaps created by DNA replication. Proc. Natl Acad. Sci. USA, 99, 16887-16892.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 16887-16892
    • Fabre, F.1    Chan, A.2    Heyer, W.D.3    Gangloff, S.4
  • 27
    • 33750025126 scopus 로고    scopus 로고
    • The role of AtMUS81 in DNA repair and its genetic interaction with the helicase AtRECQ4A
    • Hartung, F., Suer, S., Bergmann, T. and Puchta, H. (2006) The role of AtMUS81 in DNA repair and its genetic interaction with the helicase AtRECQ4A. Nucleic Acids Res., 34, 4438-4448.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 4438-4448
    • Hartung, F.1    Suer, S.2    Bergmann, T.3    Puchta, H.4
  • 28
    • 34548441649 scopus 로고    scopus 로고
    • Synthetic lethality of Drosophila in the absence of the MUS81 endonuclease and the DmBlm helicase is associated with elevated apoptosis
    • Trowbridge, K., McKim, K., Brill, S.J. and Sekelsky, J. (2007) Synthetic lethality of Drosophila in the absence of the MUS81 endonuclease and the DmBlm helicase is associated with elevated apoptosis. Genetics, 176, 1993-2001.
    • (2007) Genetics , vol.176 , pp. 1993-2001
    • Trowbridge, K.1    McKim, K.2    Brill, S.J.3    Sekelsky, J.4
  • 29
    • 77949653925 scopus 로고    scopus 로고
    • Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. Cerevisiae
    • Blanco, M.G., Matos, J., Rass, U., Ip, S.C. and West, S.C. (2010) Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae. DNA Repair (Amst.), 9, 394-402.
    • (2010) DNA Repair (Amst.) , vol.9 , pp. 394-402
    • Blanco, M.G.1    Matos, J.2    Rass, U.3    Ip, S.C.4    West, S.C.5
  • 30
    • 78650242581 scopus 로고    scopus 로고
    • Mus81 and Yen1 promote reciprocal exchange during mitotic recombination to maintain genome integrity in budding yeast
    • Ho, C.K., Mazon, G., Lam, A.F. and Symington, L.S. (2010) Mus81 and Yen1 promote reciprocal exchange during mitotic recombination to maintain genome integrity in budding yeast. Mol. Cell, 40, 988-1000.
    • (2010) Mol. Cell , vol.40 , pp. 988-1000
    • Ho, C.K.1    Mazon, G.2    Lam, A.F.3    Symington, L.S.4
  • 31
    • 77951246052 scopus 로고    scopus 로고
    • Overlapping roles for Yen1 and Mus81 in cellular Holliday junction processing
    • Tay, Y.D. and Wu, L. (2010) Overlapping roles for Yen1 and Mus81 in cellular Holliday junction processing. J. Biol. Chem., 285, 11427-11432.
    • (2010) J. Biol. Chem. , vol.285 , pp. 11427-11432
    • Tay, Y.D.1    Wu, L.2
  • 32
    • 80052426793 scopus 로고    scopus 로고
    • The role of Holliday junction resolvases in the repair of spontaneous and induced DNA damage
    • Agmon, N., Yovel, M., Harari, Y., Liefshitz, B. and Kupiec, M. (2011) The role of Holliday junction resolvases in the repair of spontaneous and induced DNA damage. Nucleic Acids Res., 39, 7009-7019.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 7009-7019
    • Agmon, N.1    Yovel, M.2    Harari, Y.3    Liefshitz, B.4    Kupiec, M.5
  • 35
    • 0043092025 scopus 로고    scopus 로고
    • Identification and characterization of the human Mus81-Eme1 endonuclease
    • Ciccia, A., Constantinou, A. and West, S.C. (2003) Identification and characterization of the human Mus81-Eme1 endonuclease. J. Biol. Chem., 278, 25172-25178.
    • (2003) J. Biol. Chem. , vol.278 , pp. 25172-25178
    • Ciccia, A.1    Constantinou, A.2    West, S.C.3
  • 36
    • 0037470059 scopus 로고    scopus 로고
    • Cleavage of model replication forks by fission yeast Mus81-Eme1 and budding yeast Mus81-Mms4
    • Whitby, M.C., Osman, F. and Dixon, J. (2003) Cleavage of model replication forks by fission yeast Mus81-Eme1 and budding yeast Mus81-Mms4. J. Biol. Chem., 278, 6928-6935.
    • (2003) J. Biol. Chem. , vol.278 , pp. 6928-6935
    • Whitby, M.C.1    Osman, F.2    Dixon, J.3
  • 37
    • 0141707817 scopus 로고    scopus 로고
    • Generating crossovers by resolution of nicked Holliday junctions: A role for Mus81-Eme1 in meiosis
    • Osman, F., Dixon, J., Doe, C.L. and Whitby, M.C. (2003) Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosis. Mol. Cell, 12, 761-774.
    • (2003) Mol. Cell , vol.12 , pp. 761-774
    • Osman, F.1    Dixon, J.2    Doe, C.L.3    Whitby, M.C.4
  • 38
    • 10044292849 scopus 로고    scopus 로고
    • Substrate specificity of the Saccharomyces cerevisiae Mus81-Mms4 endonuclease
    • Fricke, W.M., Bastin-Shanower, S.A. and Brill, S.J. (2005) Substrate specificity of the Saccharomyces cerevisiae Mus81-Mms4 endonuclease. DNA Repair (Amst.), 4, 243-251.
    • (2005) DNA Repair (Amst.) , vol.4 , pp. 243-251
    • Fricke, W.M.1    Bastin-Shanower, S.A.2    Brill, S.J.3
  • 39
    • 42449115326 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease
    • Ehmsen, K.T. and Heyer, W.D. (2008) Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease. Nucleic Acids Res., 36, 2182-2195.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 2182-2195
    • Ehmsen, K.T.1    Heyer, W.D.2
  • 40
    • 41649092091 scopus 로고    scopus 로고
    • Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures
    • Taylor, E.R. and McGowan, C.H. (2008) Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures. Proc. Natl Acad. Sci. USA, 105, 3757-3762.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 3757-3762
    • Taylor, E.R.1    McGowan, C.H.2
  • 41
    • 84864592240 scopus 로고    scopus 로고
    • Mus81-Mms4 functions as a single heterodimer to cleave nicked intermediates in recombinational DNA repair
    • Schwartz, E.K., Wright, W.D., Ehmsen, K.T., Evans, J.E., Stahlberg, H. and Heyer, W.D. (2012) Mus81-Mms4 functions as a single heterodimer to cleave nicked intermediates in recombinational DNA repair. Mol. Cell. Biol., 32, 3065-3080.
    • (2012) Mol. Cell. Biol. , vol.32 , pp. 3065-3080
    • Schwartz, E.K.1    Wright, W.D.2    Ehmsen, K.T.3    Evans, J.E.4    Stahlberg, H.5    Heyer, W.D.6
  • 42
    • 80053544629 scopus 로고    scopus 로고
    • Regulatory control of the resolution of DNA recombination intermediates during meiosis and Mitosis
    • Matos, J., Blanco, M.G., Maslen, S., Skehel, J.M. and West, S.C. (2011) Regulatory control of the resolution of DNA recombination intermediates during meiosis and Mitosis. Cell, 147, 158-172.
    • (2011) Cell , vol.147 , pp. 158-172
    • Matos, J.1    Blanco, M.G.2    Maslen, S.3    Skehel, J.M.4    West, S.C.5
  • 44
    • 84876407519 scopus 로고    scopus 로고
    • Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover
    • Szakal, B. and Branzei, D. (2013) Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover. EMBO J., 32, 1155-1167.
    • (2013) EMBO J. , vol.32 , pp. 1155-1167
    • Szakal, B.1    Branzei, D.2
  • 47
  • 48
    • 0031820288 scopus 로고    scopus 로고
    • Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
    • Longtine, M.S., McKenzie, A. III, Demarini, D.J., Shah, N.G., Wach, A., Brachat, A., Philippsen, P. and Pringle, J.R. (1998) Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast, 14, 953-961.
    • (1998) Yeast , vol.14 , pp. 953-961
    • Longtine, M.S.1    McKenzie III, A.2    Demarini, D.J.3    Shah, N.G.4    Wach, A.5    Brachat, A.6    Philippsen, P.7    Pringle, J.R.8
  • 49
    • 0033224310 scopus 로고    scopus 로고
    • G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus
    • Labib, K., Diffley, J.F.X. and Kearsey, S.E. (1999) G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus. Nat. Cell Biol., 1, 415-422.
    • (1999) Nat. Cell Biol. , vol.1 , pp. 415-422
    • Labib, K.1    Diffley, J.F.X.2    Kearsey, S.E.3
  • 50
    • 0028032104 scopus 로고
    • The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication
    • Foiani, M., Marini, F., Gamba, D., Lucchini, G. and Plevani, P. (1994) The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication. Mol. Cell. Biol., 14, 923-933.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 923-933
    • Foiani, M.1    Marini, F.2    Gamba, D.3    Lucchini, G.4    Plevani, P.5
  • 51
    • 0033570894 scopus 로고    scopus 로고
    • Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase
    • Pellicioli, A., Lucca, C., Liberi, G., Marini, F., Lopes, M., Plevani, P., Romano, A., Di Fiore, P.P. and Foiani, M. (1999) Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase. EMBO J., 18, 6561-6572.
    • (1999) EMBO J. , vol.18 , pp. 6561-6572
    • Pellicioli, A.1    Lucca, C.2    Liberi, G.3    Marini, F.4    Lopes, M.5    Plevani, P.6    Romano, A.7    Di Fiore, P.P.8    Foiani, M.9
  • 52
    • 0024285032 scopus 로고
    • Time of replication of yeast centromeres and telomeres
    • McCarroll, R.M. and Fangman, W.L. (1988) Time of replication of yeast centromeres and telomeres. Cell, 54, 505-513.
    • (1988) Cell , vol.54 , pp. 505-513
    • McCarroll, R.M.1    Fangman, W.L.2
  • 53
    • 68349151241 scopus 로고    scopus 로고
    • Density transfer as a method to analyze the progression of DNA replication forks
    • Tercero, J.A. (2009) Density transfer as a method to analyze the progression of DNA replication forks. Methods Mol. Biol., 521, 203-213.
    • (2009) Methods Mol. Biol. , vol.521 , pp. 203-213
    • Tercero, J.A.1
  • 54
    • 0035797444 scopus 로고    scopus 로고
    • Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint
    • Tercero, J.A. and Diffley, J.F. (2001) Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint. Nature, 412, 553-557.
    • (2001) Nature , vol.412 , pp. 553-557
    • Tercero, J.A.1    Diffley, J.F.2
  • 55
    • 0035312721 scopus 로고    scopus 로고
    • Monitoring S phase progression globally and locally using BrdU incorporation in TK(+) yeast strains
    • Lengronne, A., Pasero, P., Bensimon, A. and Schwob, E. (2001) Monitoring S phase progression globally and locally using BrdU incorporation in TK(+) yeast strains. Nucleic Acids Res., 29, 1433-1442.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 1433-1442
    • Lengronne, A.1    Pasero, P.2    Bensimon, A.3    Schwob, E.4
  • 56
    • 33745203040 scopus 로고    scopus 로고
    • Synthetic junctions as tools to identify and characterize Holliday junction resolvases
    • Rass, U. and West, S.C. (2006) Synthetic junctions as tools to identify and characterize Holliday junction resolvases. Methods Enzymol., 408, 485-501.
    • (2006) Methods Enzymol. , vol.408 , pp. 485-501
    • Rass, U.1    West, S.C.2
  • 57
    • 0029085781 scopus 로고
    • A checkpoint regulates the rate of progression through S phase in S. Cerevisiae in response to DNA damage
    • Paulovich, A.G. and Hartwell, L.H. (1995) A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell, 82, 841-847.
    • (1995) Cell , vol.82 , pp. 841-847
    • Paulovich, A.G.1    Hartwell, L.H.2
  • 58
    • 33344470620 scopus 로고    scopus 로고
    • Isolating apparently pure libraries of replication origins from complex genomes
    • Mesner, L.D., Crawford, E.L. and Hamlin, J.L. (2006) Isolating apparently pure libraries of replication origins from complex genomes. Mol. Cell, 21, 719-726.
    • (2006) Mol. Cell , vol.21 , pp. 719-726
    • Mesner, L.D.1    Crawford, E.L.2    Hamlin, J.L.3
  • 60
    • 0034595211 scopus 로고    scopus 로고
    • DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p
    • Tercero, J.A., Labib, K. and Diffley, J.F. (2000) DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p. EMBO J., 19, 2082-2093.
    • (2000) EMBO J. , vol.19 , pp. 2082-2093
    • Tercero, J.A.1    Labib, K.2    Diffley, J.F.3
  • 61
    • 52049108477 scopus 로고    scopus 로고
    • Multiple pathways cooperate to facilitate DNA replication fork progression through alkylated DNA
    • Vázquez, M.V., Rojas, V. and Tercero, J.A. (2008) Multiple pathways cooperate to facilitate DNA replication fork progression through alkylated DNA. DNA Repair (Amst.), 7, 1693-1704.
    • (2008) DNA Repair (Amst.) , vol.7 , pp. 1693-1704
    • Vázquez, M.V.1    Rojas, V.2    Tercero, J.A.3
  • 64
    • 0032497529 scopus 로고    scopus 로고
    • A Mec1- and Rad53- dependent checkpoint controls late-firing origins of DNA replication
    • Santocanale, C. and Diffley, J.F.X. (1998) A Mec1- and Rad53- dependent checkpoint controls late-firing origins of DNA replication. Nature, 395, 615-618.
    • (1998) Nature , vol.395 , pp. 615-618
    • Santocanale, C.1    Diffley, J.F.X.2
  • 65
    • 56749119855 scopus 로고    scopus 로고
    • Identification of Holliday junction resolvases from humans and yeast
    • Ip, S.C., Rass, U., Blanco, M.G., Flynn, H.R., Skehel, J.M. and West, S.C. (2008) Identification of Holliday junction resolvases from humans and yeast. Nature, 456, 357-361.
    • (2008) Nature , vol.456 , pp. 357-361
    • Ip, S.C.1    Rass, U.2    Blanco, M.G.3    Flynn, H.R.4    Skehel, J.M.5    West, S.C.6
  • 66
    • 79955456518 scopus 로고    scopus 로고
    • Pathways for Holliday junction processing during homologous recombination in Saccharomyces cerevisiae
    • Ashton, T.M., Mankouri, H.W., Heidenblut, A., McHugh, P.J. and Hickson, I.D. (2011) Pathways for Holliday junction processing during homologous recombination in Saccharomyces cerevisiae. Mol. Cell. Biol., 31, 1921-1933.
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 1921-1933
    • Ashton, T.M.1    Mankouri, H.W.2    Heidenblut, A.3    McHugh, P.J.4    Hickson, I.D.5
  • 68
    • 0035898405 scopus 로고    scopus 로고
    • Characterization of homologous recombination induced by replication inhibition in mammalian cells
    • Saintigny, Y., Delacote, F., Vares, G., Petitot, F., Lambert, S., Averbeck, D. and Lopez, B.S. (2001) Characterization of homologous recombination induced by replication inhibition in mammalian cells. EMBO J., 20, 3861-3870.
    • (2001) EMBO J. , vol.20 , pp. 3861-3870
    • Saintigny, Y.1    Delacote, F.2    Vares, G.3    Petitot, F.4    Lambert, S.5    Averbeck, D.6    Lopez, B.S.7
  • 69
    • 76849109722 scopus 로고    scopus 로고
    • Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair
    • Petermann, E., Orta, M.L., Issaeva, N., Schultz, N. and Helleday, T. (2010) Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair. Mol. Cell, 37, 492-502.
    • (2010) Mol. Cell , vol.37 , pp. 492-502
    • Petermann, E.1    Orta, M.L.2    Issaeva, N.3    Schultz, N.4    Helleday, T.5
  • 70
    • 39449123590 scopus 로고    scopus 로고
    • Cleavage of stalled forks by fission yeast Mus81/Eme1 in absence of DNA replication checkpoint
    • Froget, B., Blaisonneau, J., Lambert, S. and Baldacci, G. (2008) Cleavage of stalled forks by fission yeast Mus81/Eme1 in absence of DNA replication checkpoint. Mol. Biol. Cell., 19, 445-456.
    • (2008) Mol. Biol. Cell. , vol.19 , pp. 445-456
    • Froget, B.1    Blaisonneau, J.2    Lambert, S.3    Baldacci, G.4
  • 71
    • 55949108120 scopus 로고    scopus 로고
    • Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway
    • Franchitto, A., Pirzio, L.M., Prosperi, E., Sapora, O., Bignami, M. and Pichierri, P. (2008) Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway. J. Cell Biol., 183, 241-252.
    • (2008) J. Cell Biol. , vol.183 , pp. 241-252
    • Franchitto, A.1    Pirzio, L.M.2    Prosperi, E.3    Sapora, O.4    Bignami, M.5    Pichierri, P.6
  • 72
    • 37349039649 scopus 로고    scopus 로고
    • Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress
    • Shimura, T., Torres, M.J., Martin, M.M., Rao, V.A., Pommier, Y., Katsura, M., Miyagawa, K. and Aladjem, M.I. (2008) Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress. J. Mol. Biol., 375, 1152-1164.
    • (2008) J. Mol. Biol. , vol.375 , pp. 1152-1164
    • Shimura, T.1    Torres, M.J.2    Martin, M.M.3    Rao, V.A.4    Pommier, Y.5    Katsura, M.6    Miyagawa, K.7    Aladjem, M.I.8
  • 73
    • 22244474639 scopus 로고    scopus 로고
    • Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks
    • Lundin, C., North, M., Erixon, K., Walters, K., Jenssen, D., Goldman, A.S. and Helleday, T. (2005) Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks. Nucleic Acids Res., 33, 3799-3811.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 3799-3811
    • Lundin, C.1    North, M.2    Erixon, K.3    Walters, K.4    Jenssen, D.5    Goldman, A.S.6    Helleday, T.7
  • 74
    • 0022363977 scopus 로고
    • Methylation-induced blocks to in vitro DNA replication
    • Larson, K., Sahm, J., Shenkar, R. and Strauss, B. (1985) Methylation-induced blocks to in vitro DNA replication. Mutat. Res., 150, 77-84.
    • (1985) Mutat. Res. , vol.150 , pp. 77-84
    • Larson, K.1    Sahm, J.2    Shenkar, R.3    Strauss, B.4
  • 78
    • 84876333995 scopus 로고    scopus 로고
    • Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates
    • Neelsen, K.J., Zanini, I.M., Herrador, R. and Lopes, M. (2013) Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates. J. Cell Biol., 200, 699-708.
    • (2013) J. Cell Biol. , vol.200 , pp. 699-708
    • Neelsen, K.J.1    Zanini, I.M.2    Herrador, R.3    Lopes, M.4
  • 79
    • 84873412967 scopus 로고    scopus 로고
    • The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation
    • Murfuni, I., Nicolai, S., Baldari, S., Crescenzi, M., Bignami, M., Franchitto, A. and Pichierri, P. (2013) The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation. Oncogene, 32, 610-620.
    • (2013) Oncogene , vol.32 , pp. 610-620
    • Murfuni, I.1    Nicolai, S.2    Baldari, S.3    Crescenzi, M.4    Bignami, M.5    Franchitto, A.6    Pichierri, P.7


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