HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response.

PLoS pathogens

Volumn 5, Issue 10, 2009, Pages

  Ward, Jeffrey ^a   Davis, Zachary ^a   DeHart, Jason ^a   Zimmerman, Erik ^a   Bosque, Alberto ^a   Brunetta, Enrico ^a   Mavilio, Domenico ^a   Planelles, Vicente ^a   Barker, Edward ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN, HUMAN; CELL CYCLE PROTEIN; CUL4A PROTEIN, HUMAN; CULLIN; KLRK1 PROTEIN, HUMAN; MEMBRANE PROTEIN; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; UBIQUITIN PROTEIN LIGASE; ULBP1 PROTEIN, HUMAN; ULBP2 PROTEIN, HUMAN; ULBP3 PROTEIN, HUMAN; VPR PROTEIN;

ARTICLE; BIOSYNTHESIS; CD4+ T LYMPHOCYTE; DNA DAMAGE; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; METABOLISM; NATURAL KILLER CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; VIROLOGY;

CD4-POSITIVE T-LYMPHOCYTES; CELL CYCLE PROTEINS; CULLIN PROTEINS; DNA DAMAGE; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION REGULATION, VIRAL; GENE PRODUCTS, VPR; HIV INFECTIONS; HIV-1; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KILLER CELLS, NATURAL; MEMBRANE PROTEINS; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELLS; UBIQUITIN-PROTEIN LIGASES;

EID: 73349122322     PISSN: None     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000613     Document Type: Article

References (0)