Transfected poly(I:C) activates different dsRNA receptors, leading to apoptosis or immunoadjuvant response in androgen-independent prostate cancer cells

Journal of Biological Chemistry

Volumn 290, Issue 9, 2015, Pages 5470-5483

  Palchetti, Sara ^a   Starace, Donatella ^a   De Cesaris, Paola ^b   Filippini, Antonio ^a   Ziparo, Elio ^a   Riccioli, Anna ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL DEATH; CELLS; CYTOLOGY; DISEASE CONTROL; DISEASES; DRUG PRODUCTS; LIPOSOMES; RADIOTHERAPY; UROLOGY;

ANDROGEN-DEPENDENT; CYTOSOLIC RECEPTORS; GENETIC INHIBITION; PRO-APOPTOTIC EFFECTS; PROSTATE CANCER CELLS; SIGNALING PATHWAYS; THERAPEUTIC TARGETS; TOLL-LIKE RECEPTOR 3;

CELL SIGNALING;

ANDROGEN; BETA INTERFERON; CYTOSOL RECEPTOR; DOUBLE STRANDED RNA; IMMUNOLOGICAL ADJUVANT; INTERFERON REGULATORY FACTOR 3; LIPOFECTAMINE; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN MDA5; PROTEIN TYROSINE KINASE; RETINOIC ACID INDUCIBLE PROTEIN I; STAT1 PROTEIN; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; DEAD BOX PROTEIN; IFIH1 PROTEIN, HUMAN; IRF3 PROTEIN, HUMAN; POLY I-C RECEPTOR; PROTEIN KINASE P60; REUL PROTEIN, HUMAN; TLR3 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ADVANCED CANCER; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DU145 CELL LINE; ENDOSOME; GENETIC TRANSFECTION; IMMUNE RESPONSE; LNCAP CELL LINE; NONHUMAN; PC3 CELL LINE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE CANCER CELL LINE; PROTEIN EXPRESSION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; UPREGULATION; CONFOCAL MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; METABOLISM; PATHOLOGY; PROSTATE TUMOR; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL LINE; WESTERN BLOTTING;

ADJUVANTS, IMMUNOLOGIC; ANDROGENS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; DEAD-BOX RNA HELICASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; MALE; MICROSCOPY, CONFOCAL; POLY I-C; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TOLL-LIKE RECEPTOR 3; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES;

EID: 84923922464     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.601625     Document Type: Article

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