Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7

Molecular and Cellular Biology

Volumn 20, Issue 17, 2000, Pages 6342-6353

  Lin, R ^a   Genin, P ^a   Mamane, Y ^a   Hiscott, J ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CHEMOKINE; CHIMERIC PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA; HYBRID PROTEIN; RANTES; REGULATOR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; DNA BINDING; EMBRYO; GENE ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; KIDNEY CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; REGULATOR GENE; TRANSACTIVATION;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CELL LINE; CREB-BINDING PROTEIN; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMANS; IMMUNOBLOTTING; INTERFERON REGULATORY FACTOR-3; INTERFERON REGULATORY FACTOR-7; INTERFERON-ALPHA; INTERFERON-BETA; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEAR PROTEINS; PLASMIDS; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, TERTIARY; RANTES; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 0033842515     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.17.6342-6353.2000     Document Type: Article

References (48)

1. Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes
2. Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes
3. Type I interferon gene expression: Differential expression of IFN-A genes induced by viruses and double-stranded RNA
4. Unique properties of a second human herpesvirus 8-encoded interferon regulatory factor (vIRF-2)
5. Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators
6. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
7. TAF(II)250 is a bipartite protein kinase that phosphorylates the basal transcription factor RAP74
8. Structure of IRF-1 with bound DNA reveals determinants of interferon regulation
9. Reversal of intrinsic DNA bends in the IFNβ gene enhancer by transcription factors and the architectural protein HMG I(Y)
10. Crystal structure of an IRF-DNA complex reveals novel recognition of and cooperative binding to a tandem repeat of core sequences
11. Induction of endogenous IFN-α and IFN-β genes by a regulatory transcription factor IRF-1
12. Evidence for a nuclear factor(s), IRF-1, mediating induction and silencing properties to human IFN-β gene regulatory elements
13. Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes
14. Absence of type I IFN system in EC cells: Transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated
15. Differential expression of human interferon genes
16. Molecular mechanisms of interferon beta gene induction
17. Triggering the interferon response: The role of IRF-3 transcription factor
18. STATs: Signal transducers and activators of transcription
19. Primary activation of interferon A and interferon B gene transcription by interferon regulatory factory-3
20. The mechanism of transcriptional synergy of an in vitro assembled interferon-β enhanceosome
21. Interferon induction of gene expression through the Jak-Stat pathway
22. Phosphorylation of IκBα in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability
23. Essential role of IRF-3 in direct activation of RANTES gene transcription
24. Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
25. Structural and functional analysis of interferon regulatory factor 3: Localization of the transactivation and autoinhibitory domains
26. Interferon regulatory factors: The next generation
27. Differential viral induction of distinct interferon-α genes by positive feedback through interferon regulatory factor-7
28. Recruitment of CBP/p300 by the IFNβ enhanceosome is required for synergistic activation of transcription
29. Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to the IFN-β gene regulatory elements
30. The TAF(II)250 subunit of TFIID has histone acetyltransferase activity
31. Interferon-independent and -induced regulation of Epstein-Barr virus EBNA-1 gene transcription in Burkitt lymphoma
32. Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-β promoter
33. Induction of interferon alpha gene expression
34. Human papilloma-virus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity
35. Human TAFII250 interacts with RAP74: Implications for RNA polymerase II initiation
36. Cloning and expression of human TAFII250: A TBP-associated factor implicated in cell cycle regulation
37. Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7
38. Regulation of type 1 interferon gene expression by interferon regulatory factor 3
39. Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
40. Chromatin structure and RNA polymerase II connection: Implications for transcription
41. Recognition DNA sequences of interferon regulatory factor 1 (IRF-1) and IRF-2, regulators of cell growth and the interferon system
42. Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome
43. TAFs mediate transcriptional activation and promoter selectivity
44. Interferons and other cytokines
45. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-β enhancer in vivo
46. Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1
47. Direct triggering of the type I interferon system by virus infection: Activation of a transcription factor complex containing IRF-3 and CBP/p300
48. IRF-7, a new interferon regulatory factor associated with Epstein-Barr virus latency