-
1
-
-
0035909372
-
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. 2001. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor Nature 413, 732-738.
-
(2001)
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
2
-
-
79959355521
-
Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation
-
Bhattacharyya S, Zhao Y, Kay TW, Muglia LJ. 2011. Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation. Proc. Natl. Acad. Sci. U. S. A. 108, 9554, 9559.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 9559
-
-
Bhattacharyya, S.1
Zhao, Y.2
Kay, T.W.3
Muglia, L.J.4
-
3
-
-
0031820158
-
Epidermal growth factor-induced growth inhibition requires Stat1 activation
-
Bromberg JF, Fan Z, Brown C, Mendelsohn J, Darnell JE, Jr. 1998. Epidermal growth factor-induced growth inhibition requires Stat1 activation. Cell Growth Differ. 9, 505-512.
-
(1998)
Cell Growth Differ
, vol.9
, pp. 505-512
-
-
Bromberg, J.F.1
Fan, Z.2
Brown, C.3
Mendelsohn, J.4
Darnell Jr., J.E.5
-
4
-
-
34948870976
-
G1P3, an IFN-induced survival factor, antagonizes TRAIL-induced apoptosis in human myeloma cells
-
Cheriyath V, et al. 2007. G1P3, an IFN-induced survival factor, antagonizes TRAIL-induced apoptosis in human myeloma cells. J. Clin. Investig. 117, 3107-3117.
-
(2007)
J. Clin. Investig.
, vol.117
, pp. 3107-3117
-
-
Cheriyath, V.1
-
5
-
-
38649089789
-
The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I
-
Cui S, et al. 2008. The C-terminal regulatory domain is the RNA 5=-triphosphate sensor of RIG-I. Mol. Cell 29:169-179.
-
(2008)
Mol. Cell 29
, vol.169
, pp. 179
-
-
Cui, S.1
-
6
-
-
0030840464
-
STATs and gene regulation
-
1630
-
Darnell JE, Jr. 1997. STATs and gene regulation. Science 277, 1630, 1635.
-
(1997)
Science
, vol.277
, pp. 1635
-
-
Darnell Jr., J.E.1
-
7
-
-
78851471443
-
The role of Syk/CARD9 coupled C-type lectins in antifungal immunity
-
276
-
Drummond RA, Saijo S, Iwakura Y, Brown GD. 2011. The role of Syk/CARD9 coupled C-type lectins in antifungal immunity. Eur. J. Immunol. 41, 276, 281.
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 281
-
-
Drummond, R.A.1
Saijo, S.2
Iwakura, Y.3
Brown, G.D.4
-
8
-
-
0037371835
-
Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency
-
388
-
Dupuis S, et al. 2003. Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency. Nat. Genet. 33, 388, 391.
-
(2003)
Nat. Genet.
, vol.33
, pp. 391
-
-
Dupuis, S.1
-
9
-
-
37849045856
-
Establishment and maintenance of the innate antiviral response to West Nile virus involves both RIG-I and MDA5 signaling through IPS-1
-
Fredericksen BL, Keller BC, Fornek J, Katze MG, Gale M, Jr. 2008. Establishment and maintenance of the innate antiviral response to West Nile virus involves both RIG-I and MDA5 signaling through IPS-1. J. Virol. 82, 609-616.
-
(2008)
J. Virol.
, vol.82
, pp. 609-616
-
-
Fredericksen, B.L.1
Keller, B.C.2
Fornek, J.3
Katze, M.G.4
Gale Jr., M.5
-
10
-
-
34347206680
-
The human 2'-5'oligoadenylate synthetase family, unique interferon-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation
-
Hovanessian AG, Justesen J. 2007. The human 2'-5'oligoadenylate synthetase family, unique interferon-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation. Biochimie 89, 779, 788.
-
(2007)
Biochimie 89
, vol.779
, pp. 788
-
-
Hovanessian, A.G.1
Justesen, J.2
-
11
-
-
20444500880
-
Involvement of retinoic acid-inducible gene-I in the IFN-γ/STAT1 signalling pathway in BEAS-2B cells
-
Imaizumi T, et al. 2005. Involvement of retinoic acid-inducible gene-I in the IFN-γ/STAT1 signalling pathway in BEAS-2B cells. Eur. Respir. J. 25, 1077-1083.
-
(2005)
Eur. Respir. J.
, vol.25
, pp. 1077-1083
-
-
Imaizumi, T.1
-
12
-
-
81155159161
-
Polyinosinic-polycytidylic acid induces the expression of interferon-stimulated gene 20 in mesangial cells
-
Imaizumi T, et al. 2011. Polyinosinic-polycytidylic acid induces the expression of interferon-stimulated gene 20 in mesangial cells. Nephron Exp. Nephrol. 119, e40-e48.
-
(2011)
Nephron Exp. Nephrol.
, vol.119
-
-
Imaizumi, T.1
-
13
-
-
0038624558
-
NODs, intracellular proteins involved in inflammation and apoptosis
-
Inohara N, Nunez G. 2003. NODs, intracellular proteins involved in inflammation and apoptosis. Nat. Rev. Immunol. 3, 371-382.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 371-382
-
-
Inohara, N.1
Nunez, G.2
-
14
-
-
79952133903
-
RA- inducible gene-I induction augments STAT1 activation to inhibit leukemia cell proliferation
-
Jiang LJ, et al. 2011. RA-inducible gene-I induction augments STAT1 activation to inhibit leukemia cell proliferation. Proc. Natl. Acad. Sci. U. S. A. 108, 1897-1902.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 1897-1902
-
-
Jiang, L.J.1
-
15
-
-
67650527130
-
The tyrosine kinase c-Src enhances RIG-I (retinoic acid-inducible gene I)-elicited antiviral signaling
-
Johnsen IB, Nguyen TT, Bergstroem B, Fitzgerald KA, Anthonsen MW. 2009. The tyrosine kinase c-Src enhances RIG-I (retinoic acid-inducible gene I)-elicited antiviral signaling. J. Biol. Chem. 284, 19122-19131.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 19122-19131
-
-
Johnsen, I.B.1
Nguyen, T.T.2
Bergstroem, B.3
Fitzgerald, K.A.4
Anthonsen, M.W.5
-
16
-
-
22544455673
-
Cell type-specific involvement of RIG-I in antiviral response
-
Kato H, et al. 2005. Cell type-specific involvement of RIG-I in antiviral response. Immunity 23, 19, 28.
-
(2005)
Immunity 23
, vol.19
, pp. 28
-
-
Kato, H.1
-
17
-
-
46949097299
-
Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5
-
Kato H, et al. 2008. Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5. J. Exp. Med. 205, 1601-1610.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1601-1610
-
-
Kato, H.1
-
18
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato H, et al. 2006. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441, 101-105.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
-
19
-
-
31344461659
-
Innate immune recognition of viral infection
-
Kawai T, Akira S. 2006. Innate immune recognition of viral infection. Nat. Immunol. 7, 131-137.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 131-137
-
-
Kawai, T.1
Akira, S.2
-
20
-
-
27144440523
-
IPS- 1, an adaptor triggering RIG-I-and Mda5-mediated type I interferon induction
-
Kawai T, et al. 2005. IPS-1, an adaptor triggering RIG-I-and Mda5-mediated type I interferon induction. Nat. Immunol. 6, 981-988.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 981-988
-
-
Kawai, T.1
-
21
-
-
0037243222
-
IFN- lambdas mediate antiviral protection through a distinct class II cytokine receptor complex
-
Kotenko SV, et al. 2003. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat. Immunol. 4, 69, 77.
-
(2003)
Nat. Immunol.
, vol.4
, Issue.69
, pp. 77
-
-
Kotenko, S.V.1
-
22
-
-
32644449048
-
Acetylation of Stat1 modulates NF-kappaB activity
-
Kramer OH, et al. 2006. Acetylation of Stat1 modulates NF-kappaB activity. Genes Dev. 20, 473-485.
-
(2006)
Genes Dev.
, vol.20
, pp. 473-485
-
-
Kramer, O.H.1
-
24
-
-
34548656855
-
Signaling pathways downstream of patternrecognition receptors and their cross talk
-
Lee MS, Min YJ. 2007. Signaling pathways downstream of patternrecognition receptors and their cross talk. Annu. Rev. Biochem. 76, 447-480.
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 447-480
-
-
Lee, M.S.1
Min, Y.J.2
-
25
-
-
79951671973
-
New developments in the induction and antiviral effectors of type I interferon
-
Liu SY, Sanchez DJ, Cheng G. 2011. New developments in the induction and antiviral effectors of type I interferon. Curr. Opin. Immunol. 23, 57-64.
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 57-64
-
-
Liu, S.Y.1
Sanchez, D.J.2
Cheng, G.3
-
26
-
-
1642494720
-
Reactive oxygen species mediate virus-induced STAT activation, role of tyrosine phosphatases
-
Liu T, et al. 2004. Reactive oxygen species mediate virus-induced STAT activation, role of tyrosine phosphatases. J. Biol. Chem. 279, 2461-2469.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 2461-2469
-
-
Liu, T.1
-
27
-
-
0028820423
-
Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster
-
Lutfalla G, et al. 1995. Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster. EMBO J. 14, 5100, 5108.
-
(1995)
EMBO J
, vol.14
, Issue.5100
, pp. 5108
-
-
Lutfalla, G.1
-
28
-
-
0034633822
-
Influenza A and Sendai viruses induce differential chemokine gene expression and transcription factor activation in human macrophages
-
Matikainen S, et al. 2000. Influenza A and Sendai viruses induce differential chemokine gene expression and transcription factor activation in human macrophages. Virology 276, 138, 147.
-
(2000)
Virology
, vol.276
, Issue.138
, pp. 147
-
-
Matikainen, S.1
-
29
-
-
33645214581
-
Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression
-
Matikainen S, et al. 2006. Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression. J. Virol. 80, 3515-3522.
-
(2006)
J. Virol.
, vol.80
, pp. 3515-3522
-
-
Matikainen, S.1
-
30
-
-
79952537280
-
Antiviral signaling through retinoic acid-inducible gene-I-like receptors
-
Matsumiya T, Imaizumi T, Yoshida H, Satoh K. 2011. Antiviral signaling through retinoic acid-inducible gene-I-like receptors. Arch. Immunol. Ther. Exp. 59, 41-48.
-
(2011)
Arch. Immunol. Ther. Exp.
, vol.59
, pp. 41-48
-
-
Matsumiya, T.1
Imaizumi, T.2
Yoshida, H.3
Satoh, K.4
-
31
-
-
64849100338
-
The levels of retinoic acid-inducible gene I are regulated by heat shock protein 90-alpha
-
Matsumiya T, et al. 2009. The levels of retinoic acid-inducible gene I are regulated by heat shock protein 90-alpha. J. Immunol. 182, 2717-2725.
-
(2009)
J. Immunol.
, vol.182
, pp. 2717-2725
-
-
Matsumiya, T.1
-
32
-
-
77952753340
-
Characterization of synergistic induction of CX3CL1/fractalkine by TNF-alpha and IFN-gamma in vascular endothelial cells, an essential role for TNF-alpha in post-transcriptional regulation of CX3CL1
-
Matsumiya T, et al. 2010. Characterization of synergistic induction of CX3CL1/fractalkine by TNF-alpha and IFN-gamma in vascular endothelial cells, an essential role for TNF-alpha in post-transcriptional regulation of CX3CL1. J. Immunol. 184, 4205-4214.
-
(2010)
J. Immunol.
, vol.184
, pp. 4205-4214
-
-
Matsumiya, T.1
-
33
-
-
78650048628
-
Function and regulation of retinoic acid-inducible gene-I
-
Matsumiya T, Stafforini DM. 2010. Function and regulation of retinoic acid-inducible gene-I. Crit. Rev. Immunol. 30, 489, 513.
-
(2010)
Crit. Rev. Immunol.
, vol.30
, Issue.489
, pp. 513
-
-
Matsumiya, T.1
Stafforini, D.M.2
-
34
-
-
64549119779
-
Differential regulation of the OASL and OAS1 genes in response to viral infections
-
Melchjorsen J, et al. 2009. Differential regulation of the OASL and OAS1 genes in response to viral infections. J. Interferon Cytokine Res. 29, 199-207.
-
(2009)
J. Interferon Cytokine Res.
, vol.29
, pp. 199-207
-
-
Melchjorsen, J.1
-
35
-
-
13344282731
-
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
-
Meraz MA, et al. 1996. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84, 431-442.
-
(1996)
Cell
, vol.84
, pp. 431-442
-
-
Meraz, M.A.1
-
36
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, et al. 2005. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437, 1167-1172.
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
-
37
-
-
0027722486
-
Mx proteins GTPases involved in the interferon-induced antiviral state
-
Pavlovic, J, Schroder A, Blank A, Pitossi F, Staeheli P. 1993. Mx proteins, GTPases involved in the interferon-induced antiviral state. Ciba Found. Symp. 176, 233-247.
-
(1993)
Ciba Found. Symp.
, vol.176
, pp. 233-247
-
-
Pavlovic, J.1
Schroder, A.2
Blank, A.3
Pitossi, F.4
Staeheli, P.5
-
38
-
-
3042647375
-
Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection
-
Perry AK, Chow EK, Goodnough JB, Yeh WC, Cheng G. 2004. Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection. J. Exp. Med. 199, 1651-1658.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1651-1658
-
-
Perry, A.K.1
Chow, E.K.2
Goodnough, J.B.3
Yeh, W.C.4
Cheng, G.5
-
39
-
-
0032526030
-
Biological properties of recombinant alphainterferons 40th anniversary of the discovery of interferons
-
Pfeffer LM, et al. 1998. Biological properties of recombinant alphainterferons, 40th anniversary of the discovery of interferons. Cancer Res. 58, 2489, 2499.
-
(1998)
Cancer Res.
, vol.58
, Issue.2489
, pp. 2499
-
-
Pfeffer, L.M.1
-
40
-
-
18844457095
-
Mechanisms of type-I-and type-II-interferonmediated signalling
-
Platanias LC. 2005. Mechanisms of type-I-and type-II-interferonmediated signalling. Nat. Rev. Immunol. 5, 375-386.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 375-386
-
-
Platanias, L.C.1
-
41
-
-
37349009752
-
Minimal role for STAT1 in interleukin-6 signaling and actions in the murine brain
-
Sanz E, Hofer MJ, Unzeta M, Campbell IL. 2008. Minimal role for STAT1 in interleukin-6 signaling and actions in the murine brain. Glia 56, 190, 199.
-
(2008)
Glia
, vol.56
, Issue.190
, pp. 199
-
-
Sanz, E.1
Hofer, M.J.2
Unzeta, M.3
Campbell, I.L.4
-
42
-
-
0029005645
-
Elevated cellular immune responses and interferongammarelease after long-term diethylcarbamazine treatment of patients with human lymphatic filariasis
-
Sartono E, et al. 1995. Elevated cellular immune responses and interferongammarelease after long-term diethylcarbamazine treatment of patients with human lymphatic filariasis. J. Infect. Dis. 171, 1683-1687.
-
(1995)
J. Infect. Dis.
, vol.171
, pp. 1683-1687
-
-
Sartono, E.1
-
43
-
-
0029069145
-
Transcriptional responses to polypeptide ligands, the JAK-STAT pathway
-
Schindler C, Darnell JE, Jr. 1995. Transcriptional responses to polypeptide ligands, the JAK-STAT pathway. Annu. Rev. Biochem. 64, 621-651.
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 621-651
-
-
Schindler, C.1
Darnell Jr., J.E.2
-
44
-
-
0027352378
-
Interferon-induced antiviral actions and their regulation
-
Sen GC, Ransohoff RM. 1993. Interferon-induced antiviral actions and their regulation. Adv. Virus Res. 42, 57-102.
-
(1993)
Adv. Virus Res.
, vol.42
, pp. 57-102
-
-
Sen, G.C.1
Ransohoff, R.M.2
-
45
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth RB, Sun L, Ea CK, Chen ZJ. 2005. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122, 669-682.
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
46
-
-
1042301419
-
STAT1-induced apoptosis is mediated by caspases 2 3 and 7
-
Sironi JJ, Ouchi T. 2004. STAT1-induced apoptosis is mediated by caspases 2, 3, and 7. J. Biol. Chem. 279, 4066-4074.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4066-4074
-
-
Sironi, J.J.1
Ouchi, T.2
-
47
-
-
0142059241
-
Mechanism of up-regulation of human Toll-like receptor 3 secondary to infection of measles virus-attenuated strains
-
Tanabe M, et al. 2003. Mechanism of up-regulation of human Toll-like receptor 3 secondary to infection of measles virus-attenuated strains. Biochem. Biophys. Res. Commun. 311, 39-48.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.311
, pp. 39-48
-
-
Tanabe, M.1
-
48
-
-
32044442304
-
Stat1 expression is not sufficient to regulate the interferon signaling pathway in cellular immortalization
-
Tang L, Roberts PC, Kraniak JM, Li Q, Tainsky MA. 2006. Stat1 expression is not sufficient to regulate the interferon signaling pathway in cellular immortalization. J. Interferon Cytokine Res. 26, 14, 26.
-
(2006)
J. Interferon Cytokine Res.
, vol.26
, Issue.14
, pp. 26
-
-
Tang, L.1
Roberts, P.C.2
Kraniak, J.M.3
Li, Q.4
Tainsky, M.A.5
-
49
-
-
77955657499
-
STAT1 activation regulates proliferation and differentiation of renal progenitors
-
Wang H, et al. 2010. STAT1 activation regulates proliferation and differentiation of renal progenitors. Cell Signal. 22, 1717-1726.
-
(2010)
Cell Signal
, vol.22
, pp. 1717-1726
-
-
Wang, H.1
-
50
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IFN-beta signaling
-
Xu LG, et al. 2005. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol. Cell 19, 727-740.
-
(2005)
Mol. Cell
, vol.19
, pp. 727-740
-
-
Xu, L.G.1
-
51
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama M, et al. 2004. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5, 730, 737.
-
(2004)
Nat. Immunol.
, vol.5
, Issue.730
, pp. 737
-
-
Yoneyama, M.1
|