RNA species generated in vaccinia virus infected cells activate cell type-specific MDA5 or RIG-I dependent interferon gene transcription and PKR dependent apoptosis

Virology

Volumn 413, Issue 2, 2011, Pages 183-193

  Myskiw, Chad ^b   Arsenio, Janilyn ^b   Booy, Evan P ^b,c   Hammett, Craig ^a   Deschambault, Yvon ^a   Gibson, Spencer B ^b,c   Cao, Jingxin ^a,b  

^a PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

^c UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Apoptosis; DsRNA; Interferon; MDA5; PAMPs; PKR; Poxvirus; RIG I; Vaccinia virus

Indexed keywords

BETA INTERFERON; CYTOKINE; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5 PROTEIN; PROTEIN KINASE R; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BETA INTERFERON GENE; CELL SPECIFICITY; CELL STRAIN BHK; CONTROLLED STUDY; GENE; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; VACCINIA VIRUS; VIRUS CELL INTERACTION; VIRUS REPLICATION;

APOPTOSIS; CYTOKINES; DEAD-BOX RNA HELICASES; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; IMMUNITY, INNATE; INTERFERON-BETA; PROTEIN KINASES; RNA, VIRAL; VACCINIA VIRUS;

POXVIRIDAE; VACCINIA VIRUS;

EID: 79954631519     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2011.01.034     Document Type: Article

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