-
1
-
-
4644340557
-
Divergent trophoblast responses to bacterial products mediated by TLRs
-
Abrahams, V.M., Bole-Aldo, P., Kim, Y.M., Straszewski-Chavez, S.L., Chaiworapongsa, T., Romero, R., and Mor, G. (2004) Divergent trophoblast responses to bacterial products mediated by TLRs. J Imunol 173: 4286-4296.
-
(2004)
J. Imunol.
, vol.173
, pp. 4286-4296
-
-
Abrahams, V.M.1
Bole-Aldo, P.2
Kim, Y.M.3
Straszewski-Chavez, S.L.4
Chaiworapongsa, T.5
Romero, R.6
Mor, G.7
-
2
-
-
3142724031
-
Toll-like receptor signaling
-
Akira, S., and Takeda, K. (2004) Toll-like receptor signaling. Nat Rev Immunol 4: 499-511.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
3
-
-
0033618630
-
Cell activation and apoptosis by bacterial lipoproteins through Toll-like receptor-2
-
Aliprantis, A.O., Yang, R.B., Mark, M.R., Suggett, S., Devaux, B., Radolf, J.D., et al. (1999) Cell activation and apoptosis by bacterial lipoproteins through Toll-like receptor-2. Science 285: 736-739.
-
(1999)
Science
, vol.285
, pp. 736-739
-
-
Aliprantis, A.O.1
Yang, R.B.2
Mark, M.R.3
Suggett, S.4
Devaux, B.5
Radolf, J.D.6
-
4
-
-
0034601057
-
The apoptotic signaling pathway activated by Toll-like receptor 2
-
Aliprantis, A.O., Yang, R.B., Weiss, D.S., Godowski, P., and Zychlinsky, A. (2000) The apoptotic signaling pathway activated by Toll-like receptor 2. EMBO J 19: 3325-3336.
-
(2000)
EMBO J.
, vol.19
, pp. 3325-3336
-
-
Aliprantis, A.O.1
Yang, R.B.2
Weiss, D.S.3
Godowski, P.4
Zychlinsky, A.5
-
5
-
-
0034758046
-
Toll-like receptor-2 transduces signals for NF-κB activation, apoptosis and reactive oxygen species production
-
Aliprantis, A.O., Weiss, D.S., and Zychlinsky, A. (2001) Toll-like receptor-2 transduces signals for NF-κB activation, apoptosis and reactive oxygen species production. J Endotoxin Res 7: 287-291.
-
(2001)
J. Endotoxin. Res.
, vol.7
, pp. 287-291
-
-
Aliprantis, A.O.1
Weiss, D.S.2
Zychlinsky, A.3
-
6
-
-
0034577944
-
Toll-like receptor 2-mediated NF-κB activation requires Rac1-dependent pathway
-
Arbibe, L., Mira, J.P., Teusch, N., Kline, L., Guha, M., Mackman, N., et al. (2000) Toll-like receptor 2-mediated NF-κB activation requires Rac1-dependent pathway. Nat Immunol 1: 533-540.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 533-540
-
-
Arbibe, L.1
Mira, J.P.2
Teusch, N.3
Kline, L.4
Guha, M.5
Mackman, N.6
-
7
-
-
0035475338
-
Tumor necrosis factor receptor-associated factors (TRAFs)
-
Bradley, J.R., and Pober, J.S. (2001) Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene 20: 6482-6491.
-
(2001)
Oncogene
, vol.20
, pp. 6482-6491
-
-
Bradley, J.R.1
Pober, J.S.2
-
8
-
-
0032698069
-
The p38 mitogen-activated protein kinase is required for NF-κB-dependent gene expression: The role of TATA-binding protein (TBP)
-
Carter, A.B., Knudtson, K.L., Monick, M.M., and Hunninghake, G.W. (1999) The p38 mitogen-activated protein kinase is required for NF-κB-dependent gene expression: the role of TATA-binding protein (TBP). J Biol Chem 274: 30858-30863.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30858-30863
-
-
Carter, A.B.1
Knudtson, K.L.2
Monick, M.M.3
Hunninghake, G.W.4
-
9
-
-
0032544309
-
Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adaptor protein Daxx
-
Chang, H.Y., Nishitoh, H., Yang, X., Ichijo, H., and Baltimore, D. (1998) Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adaptor protein Daxx. Science 281: 1860-1863.
-
(1998)
Science
, vol.281
, pp. 1860-1863
-
-
Chang, H.Y.1
Nishitoh, H.2
Yang, X.3
Ichijo, H.4
Baltimore, D.5
-
10
-
-
0034944380
-
Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism
-
Chen, J., Fujii, K., Zhang, L., Roberts, T., and Fu, H. (2001) Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism. Proc Nat Acad Sci USA 98: 7783-7788.
-
(2001)
Proc. Nat. Acad. Sci. USA
, vol.98
, pp. 7783-7788
-
-
Chen, J.1
Fujii, K.2
Zhang, L.3
Roberts, T.4
Fu, H.5
-
11
-
-
0038182579
-
The role of apoptosis signal-regulating kinase 1 in lymphotoxin-β receptor-mediated cell death
-
Chen, M.C., Hwang, M.J., Chou, Y.C., Chen, W.H., Cheng, G., Nakano, H., et al. (2003) The role of apoptosis signal-regulating kinase 1 in lymphotoxin-β receptor-mediated cell death. J Biol Chem 278: 16073-16081.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16073-16081
-
-
Chen, M.C.1
Hwang, M.J.2
Chou, Y.C.3
Chen, W.H.4
Cheng, G.5
Nakano, H.6
-
12
-
-
11144355624
-
Positive regulation of apoptosis signal-regulating kinase 1 by hD53L1
-
Cho, S., Ko, H.M., Kim, J.M., Lee, J.A., Park, J.E., Jang, M.S., et al. (2002) Positive regulation of apoptosis signal-regulating kinase 1 by hD53L1. J Biol Chem 279: 16050-16056.
-
(2002)
J. Biol. Chem.
, vol.279
, pp. 16050-16056
-
-
Cho, S.1
Ko, H.M.2
Kim, J.M.3
Lee, J.A.4
Park, J.E.5
Jang, M.S.6
-
13
-
-
0142027916
-
Identification of a novel antiapoptotic protein that antagonizes ASK1 and CAD activities
-
Cho, S.G., Kim, J.W., Lee, Y.H., Hwang, H.S., Kim, M.S., Ryoo, K., et al. (2003) Identification of a novel antiapoptotic protein that antagonizes ASK1 and CAD activities. J Cell Biol 163: 71-81.
-
(2003)
J. Cell Biol.
, vol.163
, pp. 71-81
-
-
Cho, S.G.1
Kim, J.W.2
Lee, Y.H.3
Hwang, H.S.4
Kim, M.S.5
Ryoo, K.6
-
14
-
-
0036221384
-
MAP kinase in the immune responses
-
Dong, C., Davis, R.J., and Flavell, R.A. (2002) MAP kinase in the immune responses. Annu Rev Immunol 20: 55-72.
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 55-72
-
-
Dong, C.1
Davis, R.J.2
Flavell, R.A.3
-
15
-
-
3042782560
-
Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034
-
Fujii, K., Goldman, E.H., Park, H.R., Zhang, L., Chen, J., and Fu, H. (2004) Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034. Oncogene 23: 5099-5104.
-
(2004)
Oncogene
, vol.23
, pp. 5099-5104
-
-
Fujii, K.1
Goldman, E.H.2
Park, H.R.3
Zhang, L.4
Chen, J.5
Fu, H.6
-
16
-
-
0141886177
-
Involvement of leucine residues at positions 107, 112, and 115 in a leucine-rich repeat motif of human Toll-like receptor 2 in the recognition of diacylated lipoproteins and lipopeptides and Staphylococcus aureus peptidoglycans
-
Fujita, M., Into, T., Yasuda, M., Okusawa, T., Hamahira, S., Kuroki, Y., et al. (2003) Involvement of leucine residues at positions 107, 112, and 115 in a leucine-rich repeat motif of human Toll-like receptor 2 in the recognition of diacylated lipoproteins and lipopeptides and Staphylococcus aureus peptidoglycans. J Immunol 171: 3675-3683.
-
(2003)
J. Immunol.
, vol.171
, pp. 3675-3683
-
-
Fujita, M.1
Into, T.2
Yasuda, M.3
Okusawa, T.4
Hamahira, S.5
Kuroki, Y.6
-
17
-
-
4344613405
-
TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not Toll/IL-1 receptor domain-containing adaptor-inducing IFN-β (TRIF)-dependent pathway in TLR signaling
-
Gohda, J., Matsumura, T., and Inoue, J. (2004) TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not Toll/IL-1 receptor domain-containing adaptor-inducing IFN-β (TRIF)-dependent pathway in TLR signaling. J Immunol 173: 2913-2917.
-
(2004)
J. Immunol.
, vol.173
, pp. 2913-2917
-
-
Gohda, J.1
Matsumura, T.2
Inoue, J.3
-
18
-
-
1642410790
-
Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation
-
Goldman, E.H., Chen, L., and Fu, H. (2004) Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation. J Biol Chem 279: 10442-10449.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 10442-10449
-
-
Goldman, E.H.1
Chen, L.2
Fu, H.3
-
19
-
-
0034714355
-
Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation
-
Hatai, T., Matsuzawa, A., Inoshita, S., Mochida, Y., Kuroda, T., Sakamaki, K., et al. (2000) Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation. J Biol Chem 275: 26576-26581.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26576-26581
-
-
Hatai, T.1
Matsuzawa, A.2
Inoshita, S.3
Mochida, Y.4
Kuroda, T.5
Sakamaki, K.6
-
20
-
-
0037153130
-
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
-
Horng, T., Barton, G.M., Flavell, R.A., and Medzhitov, R. (2002) The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 420: 329-333.
-
(2002)
Nature
, vol.420
, pp. 329-333
-
-
Horng, T.1
Barton, G.M.2
Flavell, R.A.3
Medzhitov, R.4
-
21
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
Ichijo, H., Nishida, E., Irie, K., ten Dijke, P., Saitoh, M., Moriguchi, T., et al. (1997) Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275: 90-94.
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
-
22
-
-
0036239693
-
Mycoplasmal lipoproteins induce caspases- and Toll-like receptor 2-mediated cell death in lymphocytes and monocytes
-
Into, T., Nodasaka, Y., Hasebe, A., Okuzawa, T., Nakamura, J., Ohata, N., and Shibata, K. (2002a) Mycoplasmal lipoproteins induce caspases- and Toll-like receptor 2-mediated cell death in lymphocytes and monocytes. Microbiol Immunol 46: 265-276.
-
(2002)
Microbiol. Immunol.
, vol.46
, pp. 265-276
-
-
Into, T.1
Nodasaka, Y.2
Hasebe, A.3
Okuzawa, T.4
Nakamura, J.5
Ohata, N.6
Shibata, K.7
-
23
-
-
0036081275
-
Synergic effects of mycoplasmal lipopeptides and extracellular ATP on activation of macrophages
-
Into, T., Fujita, M., Okusawa, T., Hasebe, A., Morita, M., and Shibata, K. (2002b) Synergic effects of mycoplasmal lipopeptides and extracellular ATP on activation of macrophages. Infect Immun 70: 3586-3591.
-
(2002)
Infect. Immun.
, vol.70
, pp. 3586-3591
-
-
Into, T.1
Fujita, M.2
Okusawa, T.3
Hasebe, A.4
Morita, M.5
Shibata, K.6
-
24
-
-
0036035454
-
Extracellular ATP regulates cell death of lymphocytes and monocytes induced by membrane-bound lipoproteins of Mycoplasma fermentans and Mycoplasma salivarium
-
Into, T., Okada, K., Inoue, N., Yasuda, M., and Shibata, K. (2002c) Extracellular ATP regulates cell death of lymphocytes and monocytes induced by membrane-bound lipoproteins of Mycoplasma fermentans and Mycoplasma salivarium. Microbiol Immunol 46: 667-675.
-
(2002)
Microbiol. Immunol.
, vol.46
, pp. 667-675
-
-
Into, T.1
Okada, K.2
Inoue, N.3
Yasuda, M.4
Shibata, K.5
-
25
-
-
1642513702
-
Stimulation of human Toll-like receptor (TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induce apoptotic cell death after NF-κB activation
-
Into, T., Kiura, K., Yasuda, M., Kataoka, H., Inoue, N., Hasesbe, A., et al. (2004) Stimulation of human Toll-like receptor (TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induce apoptotic cell death after NF-κB activation. Cell Microbiol 6: 187-199.
-
(2004)
Cell Microbiol.
, vol.6
, pp. 187-199
-
-
Into, T.1
Kiura, K.2
Yasuda, M.3
Kataoka, H.4
Inoue, N.5
Hasesbe, A.6
-
26
-
-
0033517989
-
Lipoproteins take their Toll on the host
-
Janeway, C.A. Jr and Medzhitov, R. (1999) Lipoproteins take their Toll on the host. Curr Biol 9: R879-R882.
-
(1999)
Curr. Biol.
, vol.9
-
-
Janeway Jr., C.A.1
Medzhitov, R.2
-
27
-
-
0037292275
-
Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members
-
Janssens, S., and Beyaert, R. (2003) Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members. Mol Cell 11: 293-302.
-
(2003)
Mol. Cell
, vol.11
, pp. 293-302
-
-
Janssens, S.1
Beyaert, R.2
-
28
-
-
0035133227
-
Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
-
Kim, A.H., Khursigara, G., Sun, X., Franke, T.F., and Chao, M.V. (2001) Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol Cell Biol 21: 893-901.
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 893-901
-
-
Kim, A.H.1
Khursigara, G.2
Sun, X.3
Franke, T.F.4
Chao, M.V.5
-
29
-
-
0036453356
-
TLR2: Cellular sensor for microbial and endogenous molecular patterns
-
Kirschning, C.J., and Schumann, R.R. (2002) TLR2: cellular sensor for microbial and endogenous molecular patterns. Curr Top Microbiol Immunol 270: 121-144.
-
(2002)
Curr. Top Microbiol. Immunol.
, vol.270
, pp. 121-144
-
-
Kirschning, C.J.1
Schumann, R.R.2
-
30
-
-
4444258208
-
Mal interacts with tumor necrosis factor-associated factor (TRAF) -6 to mediate NF-κB activation by Toll-like receptor (TLR) 2 and TLR4
-
Mansell, A., Brint, E., Gould, J.A., O'Neill, L.A., and Hertzog, P.J. (2004) Mal interacts with tumor necrosis factor-associated factor (TRAF) -6 to mediate NF-κB activation by Toll-like receptor (TLR) 2 and TLR4. J Biol Chem 279: 37227-37230.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 37227-37230
-
-
Mansell, A.1
Brint, E.2
Gould, J.A.3
O'Neill, L.A.4
Hertzog, P.J.5
-
31
-
-
0036260697
-
Cellular response to oxidative stress: Signaling for suicide and survival
-
Martindale, J.L., and Holbrook, N.J. (2002) Cellular response to oxidative stress: signaling for suicide and survival. J Cell Physiol 192: 1-15.
-
(2002)
J. Cell Physiol.
, vol.192
, pp. 1-15
-
-
Martindale, J.L.1
Holbrook, N.J.2
-
32
-
-
0037174938
-
Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade
-
Matsuura, H., Nishitoh, H., Takeda, K., Matsuzawa, A., Amagasa, T., Ito, M., et al. (2002) Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade. J Biol Chem 277: 40703-40709.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40703-40709
-
-
Matsuura, H.1
Nishitoh, H.2
Takeda, K.3
Matsuzawa, A.4
Amagasa, T.5
Ito, M.6
-
33
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov, R., Preston-Hurlburt, P., and Janeway, C.A. Jr (1997) A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388: 394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
34
-
-
0033580466
-
The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway
-
Ninomiya-tsuji, J., Kishimoto, K., Hiyama, A., Inoue, J., Cao, Z., and Matsumoto, K. (1999) The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 398: 252-256.
-
(1999)
Nature
, vol.398
, pp. 252-256
-
-
Ninomiya-Tsuji, J.1
Kishimoto, K.2
Hiyama, A.3
Inoue, J.4
Cao, Z.5
Matsumoto, K.6
-
35
-
-
0032158987
-
ASK1 is essential for JNK/SAPK activation by TRAF2
-
Nishitoh, H., Saitoh, M., Mochida, Y., Takeda, K., Nakano, H., Rothe, M., et al. (1998) ASK1 is essential for JNK/SAPK activation by TRAF2. Mol Cell 2: 389-395.
-
(1998)
Mol. Cell
, vol.2
, pp. 389-395
-
-
Nishitoh, H.1
Saitoh, M.2
Mochida, Y.3
Takeda, K.4
Nakano, H.5
Rothe, M.6
-
36
-
-
0037226672
-
Mal and MyD88: Adaptor proteins involved in signal transduction by Toll-like receptors
-
O'Neill, L.A., Dunne, A., Edjeback, M., Gray, P., Jefferies, C., and Wietek, C. (2003) Mal and MyD88: adaptor proteins involved in signal transduction by Toll-like receptors. J Endotoxin Res 9: 55-59.
-
(2003)
J. Endotoxin Res.
, vol.9
, pp. 55-59
-
-
O'Neill, L.A.1
Dunne, A.2
Edjeback, M.3
Gray, P.4
Jefferies, C.5
Wietek, C.6
-
37
-
-
0036840931
-
Heat shock protein Hsp72 is a negative regulator of apoptosis signal-regulating kinase 1
-
Park, H.S., Cho, S.G., Kim, C.K., Hwang, H.S., Noh, K.T., Kim, M.S., et al. (2002) Heat shock protein Hsp72 is a negative regulator of apoptosis signal-regulating kinase 1. Mol Cell Biol 22: 7721-7730.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 7721-7730
-
-
Park, H.S.1
Cho, S.G.2
Kim, C.K.3
Hwang, H.S.4
Noh, K.T.5
Kim, M.S.6
-
38
-
-
4644350365
-
Direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysccharide-induced production of reactive oxygen species and activation of NF-κB
-
Park, H.S., Jung, H.Y., Park, E.Y., Kim, J., Lee, W.J., and Bae, Y.S. (2004) Direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysccharide-induced production of reactive oxygen species and activation of NF-κB. J Immunol 173: 3589-3593.
-
(2004)
J. Immunol.
, vol.173
, pp. 3589-3593
-
-
Park, H.S.1
Jung, H.Y.2
Park, E.Y.3
Kim, J.4
Lee, W.J.5
Bae, Y.S.6
-
39
-
-
0031463551
-
Regulation of NF-κB activation by MAP kinase cascades
-
Schulze-Osthoff, K., Ferrari, D., Riehemann, K., and Wesselborg, S. (1997) Regulation of NF-κB activation by MAP kinase cascades. Immunobiology 198: 35-49.
-
(1997)
Immunobiology
, vol.198
, pp. 35-49
-
-
Schulze-Osthoff, K.1
Ferrari, D.2
Riehemann, K.3
Wesselborg, S.4
-
40
-
-
0034548225
-
The N-terminal lipopeptide of 44-kDa membrane-bound lipoprotein of Mycoplasma salivarium is responsible for the expression of intercellular adhesion molecule-1 on the cell surface of normal gingival fibroblasts
-
Shibata, K., Hasebe, A., Into, T., Yamada, M., and Watanabe, T. (2000) The N-terminal lipopeptide of 44-kDa membrane-bound lipoprotein of Mycoplasma salivarium is responsible for the expression of intercellular adhesion molecule-1 on the cell surface of normal gingival fibroblasts. J Immunol 165: 6538-6544.
-
(2000)
J. Immunol.
, vol.165
, pp. 6538-6544
-
-
Shibata, K.1
Hasebe, A.2
Into, T.3
Yamada, M.4
Watanabe, T.5
-
41
-
-
0035847051
-
A novel superoxide-producing NAD (P) H oxidase in kidney
-
Shiose, A., Kuroda, J., Tsuruya, K., Hirai, M., Hirakata, H., Naito, S., et al. (2001) A novel superoxide-producing NAD (P) H oxidase in kidney. J Biol Chem 276: 1417-1423.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 1417-1423
-
-
Shiose, A.1
Kuroda, J.2
Tsuruya, K.3
Hirai, M.4
Hirakata, H.5
Naito, S.6
-
42
-
-
0035902482
-
Activation of NF-κB by nontypeable Hemophilus influenzae is mediated by Toll-like receptor 2-TAK1-dependent NIK-IKKα /β-IκBα and MKK3/6-p38 MAP kinase signaling pathways in epithelial cells
-
Shuto, T., Xu, H., Wang, B., Han, J., Kai, H., Gu, X.X., et al. (2001) Activation of NF-κB by nontypeable Hemophilus influenzae is mediated by Toll-like receptor 2-TAK1-dependent NIK-IKKα/β-IκBα and MKK3/6-p38 MAP kinase signaling pathways in epithelial cells. Proc Nat Acad Sci USA 98: 8774-8779.
-
(2001)
Proc. Nat. Acad. Sci. USA
, vol.98
, pp. 8774-8779
-
-
Shuto, T.1
Xu, H.2
Wang, B.3
Han, J.4
Kai, H.5
Gu, X.X.6
-
43
-
-
2142652249
-
Phosphoinositide 3-kinaase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils
-
Strassheim, D., Asehnoune, K., Park, J.S., Kim, J.Y., He, Q., Richard, D., et al. (2004) Phosphoinositide 3-kinaase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils. J Immunol 172: 5727-5733.
-
(2004)
J. Immunol.
, vol.172
, pp. 5727-5733
-
-
Strassheim, D.1
Asehnoune, K.2
Park, J.S.3
Kim, J.Y.4
He, Q.5
Richard, D.6
-
44
-
-
0036775463
-
IRAK-4 as the central TIR signaling mediator in innate immunity
-
Suzuki, N., Suzuki, S., and Yeh, W.C. (2002) IRAK-4 as the central TIR signaling mediator in innate immunity. Trends Immunol 23: 503-506.
-
(2002)
Trends Immunol.
, vol.23
, pp. 503-506
-
-
Suzuki, N.1
Suzuki, S.2
Yeh, W.C.3
-
45
-
-
0033634977
-
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
-
Takaesu, G., Kishida, S., Hiyama, A., Yamaguchi, K., Shibuya, H., Irie, K., et al. (2000) TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Mol Cell 5: 649-658.
-
(2000)
Mol. Cell
, vol.5
, pp. 649-658
-
-
Takaesu, G.1
Kishida, S.2
Hiyama, A.3
Yamaguchi, K.4
Shibuya, H.5
Irie, K.6
-
46
-
-
0346063807
-
Roles of MAPKKK ASK1 in stress-induced cell death
-
Takeda, K., Matsuzawa, A., Nishitoh, H., and Ichijo, H. (2002) Roles of MAPKKK ASK1 in stress-induced cell death. Cell Struct Funct 28: 23-29.
-
(2002)
Cell Struct. Funct.
, vol.28
, pp. 23-29
-
-
Takeda, K.1
Matsuzawa, A.2
Nishitoh, H.3
Ichijo, H.4
-
47
-
-
0012929728
-
Toll-like receptors
-
Takeda, K., Kaisho, T., and Akira, T. (2003) Toll-like receptors. Annu Rev Immunol 21: 335-376.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 335-376
-
-
Takeda, K.1
Kaisho, T.2
Akira, T.3
-
48
-
-
0037400611
-
Molecular recognitions in the MAP kinase cascades
-
Tanoue, T., and Nishida, E. (2003) Molecular recognitions in the MAP kinase cascades. Cell Signal 15: 455-462.
-
(2003)
Cell Signal
, vol.15
, pp. 455-462
-
-
Tanoue, T.1
Nishida, E.2
-
49
-
-
2942741132
-
The low molecular weight GTPase RhoA and atypical proten kinase Cζ are required for TLR2-mediated gene transcription
-
Teusch, N., Lombardo, E., Eddleston, J., and Knaus, U.G. (2004) The low molecular weight GTPase RhoA and atypical proten kinase Cζ are required for TLR2-mediated gene transcription. J Immunol 173: 507-514.
-
(2004)
J. Immunol.
, vol.173
, pp. 507-514
-
-
Teusch, N.1
Lombardo, E.2
Eddleston, J.3
Knaus, U.G.4
-
50
-
-
0035065836
-
ASK1 is required for sustained activation of JNK/p38 MAP kinase and apoptosis
-
Tobiume, K., Matsuzawa, A., Takahashi, T., Nishitoh, H., Morita, K., Takeda, K., et al. (2001) ASK1 is required for sustained activation of JNK/p38 MAP kinase and apoptosis. EMBO Rep 2: 222-228.
-
(2001)
EMBO Rep.
, vol.2
, pp. 222-228
-
-
Tobiume, K.1
Matsuzawa, A.2
Takahashi, T.3
Nishitoh, H.4
Morita, K.5
Takeda, K.6
-
51
-
-
0142043984
-
Redox signaling and the MAP kinase pathways
-
Torres, M., and Forman, H.J. (2003) Redox signaling and the MAP kinase pathways. Biofactors 17: 287-296.
-
(2003)
Biofactors
, vol.17
, pp. 287-296
-
-
Torres, M.1
Forman, H.J.2
-
52
-
-
0036019932
-
Redox control of cell death
-
Ueda, S., Masutani, H., Nakamura, H., Tanaka, T., Ueno, M., and Yodoi, J. (2002) Redox control of cell death. Antioxid Redox Signal 4: 405-414.
-
(2002)
Antioxid. Redox. Signal
, vol.4
, pp. 405-414
-
-
Ueda, S.1
Masutani, H.2
Nakamura, H.3
Tanaka, T.4
Ueno, M.5
Yodoi, J.6
-
53
-
-
0032488837
-
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor
-
Vanden Berghe, W., Plaisance, S., Boone, E., Bosscher, K. Schmitz, M.L., Fiers, W., and Haegeman, G. (1998) p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor. J Biol Chem 273: 3285-3290.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3285-3290
-
-
Vanden Berghe, W.1
Plaisance, S.2
Boone, E.3
Bosscher, K.4
Schmitz, M.L.5
Fiers, W.6
Haegeman, G.7
-
54
-
-
0037153191
-
Essential roles for TIRAP in activation of the signaling cascade shared by TLR2 and TLR4
-
Yamamoto, M., Sato, S., Hemmmi, H., Sanjo, H., Uematsu, S., Kaisho, T., et al. (2002) Essential roles for TIRAP in activation of the signaling cascade shared by TLR2 and TLR4. Nature 420: 324-329.
-
(2002)
Nature
, vol.420
, pp. 324-329
-
-
Yamamoto, M.1
Sato, S.2
Hemmmi, H.3
Sanjo, H.4
Uematsu, S.5
Kaisho, T.6
-
55
-
-
0035736546
-
Redox regulation by the human thioredoxin system
-
Yodoi, J., Masutani, H., and Nakamura, H. (2001) Redox regulation by the human thioredoxin system. Biofactors 15: 107-111.
-
(2001)
Biofactors
, vol.15
, pp. 107-111
-
-
Yodoi, J.1
Masutani, H.2
Nakamura, H.3
-
56
-
-
0038342509
-
AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: Implication of AKT2 in chemoresistance
-
Yuan, Z.Q., Feldman, R.I., Sussman, G.E., Coppola, D., Nicosia, S.V., and Cheng, J.Q. (2003) AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. J Biol Chem 278: 23432-23440.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 23432-23440
-
-
Yuan, Z.Q.1
Feldman, R.I.2
Sussman, G.E.3
Coppola, D.4
Nicosia, S.V.5
Cheng, J.Q.6
-
57
-
-
0041743148
-
AIP1 mediates TNF-α-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3
-
Zhang, R., He, X., Liu, W., Lu, M., Hsieh, J.T., and Min, W. (2003) AIP1 mediates TNF-α-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3. J Clin Invest 111: 1933-1943.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1933-1943
-
-
Zhang, R.1
He, X.2
Liu, W.3
Lu, M.4
Hsieh, J.T.5
Min, W.6
-
58
-
-
1542377424
-
A Toll-like receptor that prevents infection by uropathogenic bacteria
-
Zhang, D., Zhang, G., Hayden, M.S., Greenblatt, M.B., Bussey, C., Flavell, R.A., and Ghosh, S. (2004a) A Toll-like receptor that prevents infection by uropathogenic bacteria. Science 303: 1522-1526.
-
(2004)
Science
, vol.303
, pp. 1522-1526
-
-
Zhang, D.1
Zhang, G.2
Hayden, M.S.3
Greenblatt, M.B.4
Bussey, C.5
Flavell, R.A.6
Ghosh, S.7
-
59
-
-
7244253045
-
AIP/DA2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation
-
Zhang, H., Zhang, R., Luo, Y., D'Alessio, A., Pober, J.S., and Min, W. (2004b) AIP/DA2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation. J Biol Chem 279: 44955-44965.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44955-44965
-
-
Zhang, H.1
Zhang, R.2
Luo, Y.3
D'Alessio, A.4
Pober, J.S.5
Min, W.6
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