MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus

Immunity

Volumn 24, Issue 1, 2006, Pages 79-91

  Miller, Lloyd S ^a   O'Connell, Ryan M ^a   Gutierrez, Miguel A ^a   Pietras, Eric M ^a   Shahangian, Arash ^a   Gross, Catherine E ^a   Thirumala, Ajaykumar ^b   Cheung, Ambrose L ^b   Cheng, Genhong ^a   Modlin, Robert L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1 RECEPTOR; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COUNT; BACTERIAL IMMUNITY; BIOLUMINESCENCE; BONE MARROW CELL; CELL TRANSPORT; CONTROLLED STUDY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKIN CELL; SKIN INFECTION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; WILD TYPE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BONE MARROW CELLS; CHEMOKINES; CYTOKINES; MICE; MICE, MUTANT STRAINS; MYELOID DIFFERENTIATION FACTOR 88; NEUTROPHIL INFILTRATION; RECEPTORS, INTERLEUKIN-1; SKIN; STAPHYLOCOCCAL SKIN INFECTIONS; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTOR 2;

EID: 30444459066     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2005.11.011     Document Type: Article

References (40)

1. O. Adachi, T. Kawai, K. Takeda, M. Matsumoto, H. Tsutsui, M. Sakagami, K. Nakanishi, and S. Akira Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function Immunity 9 1998 143 150
2. S. Akira, and K. Takeda Toll-like receptor signalling Nat. Rev. Immunol. 4 2004 499 511
3. H.D. Brightbill, D.H. Libraty, S.R. Krutzik, R.B. Yang, J.T. Belisle, J.R. Bleharski, M. Maitland, M.V. Norgard, S.E. Plevy, and S.T. Smale Host defense mechanisms triggered by microbial lipoproteins through Toll-like receptors Science 285 1999 732 736
4. C.A. Dinarello Biologic basis for interleukin-1 in disease Blood 87 1996 2095 2147
5. S. Doyle, S. Vaidya, R. O'Connell, H. Dadgostar, P. Dempsey, T. Wu, G. Rao, R. Sun, M. Haberland, R. Modlin, and G. Cheng IRF3 mediates a TLR3/TLR4-specific antiviral gene program Immunity 17 2002 251 263
6. S.E. Doyle, R. O'Connell, S.A. Vaidya, E.K. Chow, K. Yee, and G. Cheng Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4 J. Immunol. 170 2003 3565 3571
7. S.E. Doyle, R.M. O'Connell, G.A. Miranda, S.A. Vaidya, E.K. Chow, P.T. Liu, S. Suzuki, N. Suzuki, R.L. Modlin, and W.C. Yeh Toll-like receptors induce a phagocytic gene program through p38 J. Exp. Med. 199 2004 81 90
8. J. Fan, R.S. Frey, and A.B. Malik TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase J. Clin. Invest. 112 2003 1234 1243
9. K.A. Fitzgerald, and L.A. O'Neill The role of the interleukin-1/Toll-like receptor superfamily in inflammation and host defense Microbes Infect. 2 2000 933 943
10. K.P. Francis, D. Joh, C. Bellinger-Kawahara, M.J. Hawkinson, T.F. Purchio, and P.R. Contag Monitoring bioluminescent Staphylococcus aureus infections in living mice using a novel luxABCDE construct Infect. Immun. 68 2000 3594 3600
11. S.K. Fridkin, J.C. Hageman, M. Morrison, L.T. Sanza, K. Como-Sabetti, J.A. Jernigan, K. Harriman, L.H. Harrison, R. Lynfield, and M.M. Farley Methicillin-resistant Staphylococcus aureus disease in three communities N. Engl. J. Med. 352 2005 1436 1444
12. K. Hoebe, P. Georgel, S. Rutschmann, X. Du, S. Mudd, K. Crozat, S. Sovath, L. Shamel, T. Hartung, U. Zahringer, and B. Beutler CD36 is a sensor of diacylglycerides Nature 433 2005 523 527
13. T. Horng, G.M. Barton, R.A. Flavell, and R. Medzhitov The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors Nature 420 2002 329 333
14. M.J. Horsburgh, J.L. Aish, I.J. White, L. Shaw, J.K. Lithgow, and S.J. Foster sigmaB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4 J. Bacteriol. 184 2002 5457 5467
15. O.H. Hultgren, L. Svensson, and A. Tarkowski Critical role of signaling through IL-1 receptor for development of arthritis and sepsis during Staphylococcus aureus infection J. Immunol. 168 2002 5207 5212
16. S.B. Joseph, M.N. Bradley, A. Castrillo, K.W. Bruhn, P.A. Mak, L. Pei, J. Hogenesch, R.M. O'Connell, G. Cheng, and E. Saez LXR-dependent gene expression is important for macrophage survival and the innate immune response Cell 119 2004 299 309
17. T. Kawai, O. Adachi, T. Ogawa, K. Takeda, and S. Akira Unresponsiveness of MyD88-deficient mice to endotoxin Immunity 11 1999 115 122
18. T. Kielian, B. Barry, and W.F. Hickey CXC chemokine receptor-2 ligands are required for neutrophil-mediated host defense in experimental brain abscesses J. Immunol. 166 2001 4634 4643
19. T. Kielian, E.D. Bearden, A.C. Baldwin, and N. Esen IL-1 and TNF-alpha play a pivotal role in the host immune response in a mouse model of Staphylococcus aureus-induced experimental brain abscess J. Neuropathol. Exp. Neurol. 63 2004 381 396
20. S.R. Krutzik, M.T. Ochoa, P.A. Sieling, S. Uematsu, Y.W. Ng, A. Legaspi, P.T. Liu, S.T. Cole, P.J. Godowski, and Y. Maeda Activation and regulation of Toll-like receptors 2 and 1 in human leprosy Nat. Med. 9 2003 525 532
21. T.S. Kupper, and R.C. Fuhlbrigge Immune surveillance in the skin: mechanisms and clinical consequences Nat. Rev. Immunol. 4 2004 211 222
22. E.A. Kurt-Jones, L. Mandell, C. Whitney, A. Padgett, K. Gosselin, P.E. Newburger, and R.W. Finberg Role of Toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils Blood 100 2002 1860 1868
23. F.D. Lowy Staphylococcus aureus infections N. Engl. J. Med. 339 1998 520 532
24. R. Malaviya, T. Ikeda, E. Ross, and S.N. Abraham Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-alpha Nature 381 1996 77 80
25. M.U. Martin, and H. Wesche Summary and comparison of the signaling mechanisms of the Toll/Interleukin-1 receptor family Biochim. Biophys. Acta 1592 2002 265 280
26. D.C. Melles, R.F. Gorkink, H.A. Boelens, S.V. Snijders, J.K. Peeters, M.J. Moorhouse, P.J. van der Spek, W.B. van Leeuwen, G. Simons, H.A. Verbrugh, and A. van Belkum Natural population dynamics and expansion of pathogenic clones of Staphylococcus aureus J. Clin. Invest. 114 2004 1732 1740
27. L.S. Miller, O.E. Sorensen, P.T. Liu, H.R. Jalian, D. Eshtiaghpour, B.E. Behmanesh, W. Chung, T.D. Starner, J. Kim, and P.A. Sieling TGF-alpha regulates TLR expression and function on epidermal keratinocytes J. Immunol. 174 2005 6137 6143
28. L. Molne, M. Verdrengh, and A. Tarkowski Role of neutrophil leukocytes in cutaneous infection caused by Staphylococcus aureus Infect. Immun. 68 2000 6162 6167
29. J.E. Murphy, C. Robert, and T.S. Kupper Interleukin-1 and cutaneous inflammation: a crucial link between innate and acquired immunity J. Invest. Dermatol. 114 2000 602 608
30. R.P. Novick The Staphylococcus as a molecular genetic system R.P. Novick Molecular Biology of the Staphylococcus 1990 VCH Publishers New York 1 40
31. S.N. Qazi, E. Counil, J. Morrissey, C.E. Rees, A. Cockayne, K. Winzer, W.C. Chan, P. Williams, and P.J. Hill agr expression precedes escape of internalized Staphylococcus aureus from the host endosome Infect. Immun. 69 2001 7074 7082
32. S.J. Skerrett, H.D. Liggitt, A.M. Hajjar, and C.B. Wilson Cutting edge: myeloid differentiation factor 88 is essential for pulmonary host defense against Pseudomonas aeruginosa but not Staphylococcus aureus J. Immunol. 172 2004 3377 3381
33. M.B. Steen, F.L. Tuck, and R.S. Selvan Spontaneous activation of endothelial cells: a central role for endogenous IL-1alpha In Vitro Cell. Dev. Biol. Anim. 35 1999 327 332
34. O. Takeuchi, K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components Immunity 11 1999 443 451
35. O. Takeuchi, K. Hoshino, and S. Akira Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection J. Immunol. 165 2000 5392 5396
36. O. Takeuchi, T. Kawai, P.F. Muhlradt, M. Morr, J.D. Radolf, A. Zychlinsky, K. Takeda, and S. Akira Discrimination of bacterial lipoproteins by Toll-like receptor 6 Int. Immunol. 13 2001 933 940
37. O. Takeuchi, S. Sato, T. Horiuchi, K. Hoshino, K. Takeda, Z. Dong, R.L. Modlin, and S. Akira Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins J. Immunol. 169 2002 10 14
38. Y. Tsuda, H. Takahashi, M. Kobayashi, T. Hanafusa, D.N. Herndon, and F. Suzuki Three different neutrophil subsets exhibited in mice with different susceptibilities to infection by methicillin-resistant Staphylococcus aureus Immunity 21 2004 215 226
39. M. Verdrengh, J.A. Thomas, and O.H. Hultgren IL-1 receptor-associated kinase 1 mediates protection against Staphylococcus aureus infection Microbes Infect. 6 2004 1268 1272
40. Y. Zhang, B.F. Ramos, and B.A. Jakschik Neutrophil recruitment by tumor necrosis factor from mast cells in immune complex peritonitis Science 258 1992 1957 1959