Glycogen synthase kinase-3β stabilizes the interleukin (IL)-22 receptor from proteasomal degradation in murine lung epithelia

Journal of Biological Chemistry

Volumn 289, Issue 25, 2014, Pages 17610-17619

  Weathington, Nathaniel M ^a   Snavely, Courtney A ^a   Chen, Bill B ^a   Zhao, Jing ^a   Zhao, Yutong ^a   Mallampalli, Rama K ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELLS; CHEMICAL COMPOUNDS; CYTOLOGY; ENZYME ACTIVITY; PHOSPHORYLATION;

C-TERMINAL DOMAINS; CYTOSKELETAL PROTEINS; GLYCOGEN SYNTHASE KINASE; GLYCOGEN SYNTHASE KINASE-3; MOLECULAR REGULATION; PROTEASOMAL DEGRADATION; PROTEIN STABILITY; SITE DIRECTED MUTAGENESIS;

PROTEINS;

CORTACTIN; GLYCOGEN SYNTHASE KINASE 3BETA; INTERLEUKIN 22; INTERLEUKIN 22 RECEPTOR; LYSINE; PROTEASOME; PROTEIN VARIANT; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CARBOXY TERMINAL SEQUENCE; CELL SPREADING; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME INACTIVATION; ENZYME LOCALIZATION; EPITHELIUM CELL; INTRACELLULAR SIGNALING; LUNG ALVEOLUS EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; SITE DIRECTED MUTAGENESIS; UPREGULATION;

CYTOKINE; GLYCOGEN SYNTHASE KINASE 3 (GSK-3); INFLAMMATION; LUNG INJURY; PROTEIN DEGRADATION;

ANIMALS; CELL LINE; EPITHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; GLYCOGEN SYNTHASE KINASE 3; LUNG; MICE; MUTAGENESIS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STABILITY; PROTEOLYSIS; RECEPTORS, INTERLEUKIN; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; UBIQUITIN;

EID: 84903479494     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.551747     Document Type: Article

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