메뉴 건너뛰기




Volumn 183, Issue 1, 2009, Pages 687-695

Expression of IL-24, an activator of the JAK1/STAT3/SOCS3 cascade, is enhanced in inflammatory bowel disease

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; INTERLEUKIN 1BETA; INTERLEUKIN 24; JANUS KINASE 1; MUCIN 1; MUCIN 3; MUCIN 4; SALICYLIC ACID; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTION FACTOR AP 1; INTERLEUKIN DERIVATIVE; INTERLEUKIN-24; JAK1 PROTEIN, HUMAN; MUCIN; SOCS3 PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN; SUPPRESSOR OF CYTOKINE SIGNALING;

EID: 68949122797     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0804169     Document Type: Article
Times cited : (126)

References (65)
  • 1
    • 33847632044 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Past, present, and future
    • Sands, B. E. 2007. Inflammatory bowel disease: past, present, and future. J. Gastroenterol. 42: 16-25.
    • (2007) J. Gastroenterol. , vol.42 , pp. 16-25
    • Sands, B.E.1
  • 2
    • 40149092512 scopus 로고    scopus 로고
    • Inflammatory bowel disease, past, present and future: Lessons from animal models
    • Mizoguchi, A., and E. Mizoguchi. 2008. Inflammatory bowel disease, past, present and future: lessons from animal models. J. Gastroenterol. 43: 1-17.
    • (2008) J. Gastroenterol. , vol.43 , pp. 1-17
    • Mizoguchi, A.1    Mizoguchi, E.2
  • 3
    • 0029558740 scopus 로고
    • Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression
    • Jiang, H., J. J. Lin, Z. Z. Su, N. I. Goldstein, and P. B. Fisher. 1995. Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. Oncogene 11: 2477-2486.
    • (1995) Oncogene , vol.11 , pp. 2477-2486
    • Jiang, H.1    Lin, J.J.2    Su, Z.Z.3    Goldstein, N.I.4    Fisher, P.B.5
  • 4
    • 1642432084 scopus 로고    scopus 로고
    • The class II cytokine receptor (CRF2) family: Overview and patterns of receptor-ligand interactions
    • Langer, J. A., E. C. Cutrone, and S. Kotenko. 2004. The class II cytokine receptor (CRF2) family: overview and patterns of receptor-ligand interactions. Cytokine Growth Factor Rev. 15: 33-48.
    • (2004) Cytokine Growth Factor Rev. , vol.15 , pp. 33-48
    • Langer, J.A.1    Cutrone, E.C.2    Kotenko, S.3
  • 5
    • 0037097637 scopus 로고    scopus 로고
    • The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24
    • Caudell, E. G., J. B. Mumm, N. Poindexter, S. Ekmekcioglu, A. M. Mhashilkar, X. H. Yang, M. W. Retter, P. Hill, S. Chada, and E. A. Grimm. 2002. The protein product of the tumor suppressor gene, melanoma differentiation- associated gene 7, exhibits immunostimulatory activity and is designated IL-24. J. Immunol. 168: 6041-6046.
    • (2002) J. Immunol. , vol.168 , pp. 6041-6046
    • Caudell, E.G.1    Mumm, J.B.2    Poindexter, N.3    Ekmekcioglu, S.4    Mhashilkar, A.M.5    Yang, X.H.6    Retter, M.W.7    Hill, P.8    Chada, S.9    Grimm, E.A.10
  • 6
    • 0035950553 scopus 로고    scopus 로고
    • Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties
    • Huang, E. Y., M. T. Madireddi, R. V. Gopalkrishnan, M. Leszczyniecka, Z. Su, I. V. Lebedeva, D. Kang, H. Jiang, J. J. Lin, D. Alexandre, et al. 2001. Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties. Oncogene 20: 7051-7063.
    • (2001) Oncogene , vol.20 , pp. 7051-7063
    • Huang, E.Y.1    Madireddi, M.T.2    Gopalkrishnan, R.V.3    Leszczyniecka, M.4    Su, Z.5    Lebedeva, I.V.6    Kang, D.7    Jiang, H.8    Lin, J.J.9    Alexandre, D.10
  • 7
    • 0036510539 scopus 로고    scopus 로고
    • Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2
    • Wang, M., Z. Tan, R. Zhang, S. V. Kotenko, and P. Liang. 2002. Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. J. Biol. Chem. 277: 7341-7347.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7341-7347
    • Wang, M.1    Tan, Z.2    Zhang, R.3    Kotenko, S.V.4    Liang, P.5
  • 8
    • 13444269091 scopus 로고    scopus 로고
    • Interleukin-24 and its receptors
    • Wang, M., and P. Liang. 2005. Interleukin-24 and its receptors. Immunology 114: 166-170.
    • (2005) Immunology , vol.114 , pp. 166-170
    • Wang, M.1    Liang, P.2
  • 9
    • 0035478639 scopus 로고    scopus 로고
    • Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types
    • Dumoutier, L., C. Leemans, D. Lejeune, S. V. Kotenko, and J. C. Renauld. 2001. Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types. J. Immunol. 167: 3545-3549. (Pubitemid 32910793)
    • (2001) Journal of Immunology , vol.167 , Issue.7 , pp. 3545-3549
    • Dumoutier, L.1    Leemans, C.2    Lejeune, D.3    Kotenko, S.V.4    Renauld, J.-C.5
  • 10
    • 0036091086 scopus 로고    scopus 로고
    • Viral and cellular interleukin-10 (IL-10)-related cytokines: From structures to functions
    • Dumoutier, L., and J. C. Renauld. 2002. Viral and cellular interleukin-10 (IL-10)-related cytokines: from structures to functions. Eur. Cytokine Netw. 13: 5-15. (Pubitemid 34535567)
    • (2002) European Cytokine Network , vol.13 , Issue.1 , pp. 5-15
    • Dumoutier, L.1    Renauld, J.-C.2
  • 11
    • 2142653517 scopus 로고    scopus 로고
    • Expression patterns of IL-10 ligand and receptor gene families provide leads for biological characterization
    • Nagalakshmi, M. L., E. Murphy, T. McClanahan, and R. de Waal Malefyt. 2004. Expression patterns of IL-10 ligand and receptor gene families provide leads for biological characterization. Int. Immunopharmacol. 4: 577-592.
    • (2004) Int. Immunopharmacol. , vol.4 , pp. 577-592
    • Nagalakshmi, M.L.1    Murphy, E.2    McClanahan, T.3    De Waal Malefyt, R.4
  • 12
    • 33750628576 scopus 로고    scopus 로고
    • Interleukin (IL)-19, IL-20 and IL-24 are produced by and act on keratinocytes and are distinct from classical ILs
    • Kunz, S., K. Wolk, E. Witte, K. Witte, W. D. Doecke, H. D. Volk, W. Sterry, K. Asadullah, and R. Sabat. 2006. Interleukin (IL)-19, IL-20 and IL-24 are produced by and act on keratinocytes and are distinct from classical ILs. Exp. Dermatol. 15: 991-1004.
    • (2006) Exp. Dermatol. , vol.15 , pp. 991-1004
    • Kunz, S.1    Wolk, K.2    Witte, E.3    Witte, K.4    Doecke, W.D.5    Volk, H.D.6    Sterry, W.7    Asadullah, K.8    Sabat, R.9
  • 13
    • 0036604122 scopus 로고    scopus 로고
    • Cutting edge: Immune cells as sources and targets of the IL-10 family members?
    • Wolk, K., S. Kunz, K. Asadullah, and R. Sabat. 2002. Cutting edge: immune cells as sources and targets of the IL-10 family members? J. Immunol. 168: 5397-5402.
    • (2002) J. Immunol. , vol.168 , pp. 5397-5402
    • Wolk, K.1    Kunz, S.2    Asadullah, K.3    Sabat, R.4
  • 15
    • 57149138049 scopus 로고    scopus 로고
    • IL-24: A classic cytokine and/or a potential cure for cancer?
    • Kreis, S., D. Philippidou, C. Margue, and I. Behrmann. 2008. IL-24: a classic cytokine and/or a potential cure for cancer? J. Cell Mol. Med. 12: 2505-2510.
    • (2008) J. Cell Mol. Med. , vol.12 , pp. 2505-2510
    • Kreis, S.1    Philippidou, D.2    Margue, C.3    Behrmann, I.4
  • 19
    • 0344258425 scopus 로고    scopus 로고
    • Cutaneous rat wounds express c49a, a novel gene with homology to the human melanoma differentiation associated gene, mda-7
    • Soo, C., W. W. Shaw, E. Freymiller, M. T. Longaker, C. N. Bertolami, R. Chiu, A. Tieu, and K. Ting. 1999. Cutaneous rat wounds express c49a, a novel gene with homology to the human melanoma differentiation associated gene, mda-7. J. Cell Biochem. 74: 1-10.
    • (1999) J. Cell Biochem. , vol.74 , pp. 1-10
    • Soo, C.1    Shaw, W.W.2    Freymiller, E.3    Longaker, M.T.4    Bertolami, C.N.5    Chiu, R.6    Tieu, A.7    Ting, K.8
  • 20
    • 0024587677 scopus 로고
    • Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: A randomised trial
    • Rachmilewitz, D. 1989. Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial. Br. Med. J. 298: 82-86.
    • (1989) Br. Med. J. , vol.298 , pp. 82-86
    • Rachmilewitz, D.1
  • 21
    • 0018292707 scopus 로고
    • Rederived values of the eight coefficients of the Crohn's Disease Activity Index (CDAI)
    • Best, W. R., J. M. Becktel, and J. W. Singleton. 1979. Rederived values of the eight coefficients of the Crohn's Disease Activity Index (CDAI). Gastroenterology 77: 843-846.
    • (1979) Gastroenterology , vol.77 , pp. 843-846
    • Best, W.R.1    Becktel, J.M.2    Singleton, J.W.3
  • 23
    • 0031408125 scopus 로고    scopus 로고
    • Adult human colonic subepithelial myofibroblasts express extracellular matrix proteins and cyclooxygenase-1 and -2
    • Mahida, Y. R., J. Beltinger, S. Makh, M. Goke, T. Gray, D. K. Podolsky, and C. J. Hawkey. 1997. Adult human colonic subepithelial myofibroblasts express extracellular matrix proteins and cyclooxygenase-1 and -2. Am. J. Physiol. 273: G1341-G1348.
    • (1997) Am. J. Physiol. , vol.273
    • Mahida, Y.R.1    Beltinger, J.2    Makh, S.3    Goke, M.4    Gray, T.5    Podolsky, D.K.6    Hawkey, C.J.7
  • 24
    • 0036008967 scopus 로고    scopus 로고
    • Interleukin-1beta and tumor necrosis factor-α induce chemokine and matrix metalloproteinase gene expression in human colonic subepithelial myofibroblasts
    • Okuno, T., A. Andoh, S. Bamba, Y. Araki, Y. Fujiyama, M. Fujiyama, and T. Bamba. 2002. Interleukin-1beta and tumor necrosis factor-α induce chemokine and matrix metalloproteinase gene expression in human colonic subepithelial myofibroblasts. Scand. J. Gastroenterol. 37: 317-324.
    • (2002) Scand. J. Gastroenterol. , vol.37 , pp. 317-324
    • Okuno, T.1    Andoh, A.2    Bamba, S.3    Araki, Y.4    Fujiyama, Y.5    Fujiyama, M.6    Bamba, T.7
  • 25
    • 0022002954 scopus 로고
    • Enterocytic differentiation of a subpopulation of the human colon tumor cell line HT-29 selected for growth in sugar-free medium and its inhibition by glucose
    • Zweibaum, A., M. Pinto, G. Chevalier, E. Dussaulx, N. Triadou, B. Lacroix, K. Haffen, J. L. Brun, and M. Rousset. 1985. Enterocytic differentiation of a subpopulation of the human colon tumor cell line HT-29 selected for growth in sugar-free medium and its inhibition by glucose. J. Cell Physiol. 122: 21-29.
    • (1985) J. Cell Physiol. , vol.122 , pp. 21-29
    • Zweibaum, A.1    Pinto, M.2    Chevalier, G.3    Dussaulx, E.4    Triadou, N.5    Lacroix, B.6    Haffen, K.7    Brun, J.L.8    Rousset, M.9
  • 27
    • 0032508704 scopus 로고    scopus 로고
    • Differences in the migration capacity of primary human colon carcinoma cells (SW480) and their lymph node metastatic derivatives (SW620)
    • Kubens, B. S., and K. S. Zanker. 1998. Differences in the migration capacity of primary human colon carcinoma cells (SW480) and their lymph node metastatic derivatives (SW620). Cancer Lett. 131: 55-64.
    • (1998) Cancer Lett. , vol.131 , pp. 55-64
    • Kubens, B.S.1    Zanker, K.S.2
  • 29
    • 0034613201 scopus 로고    scopus 로고
    • Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R
    • Xie, M. H., S. Aggarwal, W. H. Ho, J. Foster, Z. Zhang, J. Stinson, W. I. Wood, A. D. Goddard, and A. L. Gurney. 2000. Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J. Biol. Chem. 275: 31335-31339.
    • (2000) J. Biol. Chem. , vol.275 , pp. 31335-31339
    • Xie, M.H.1    Aggarwal, S.2    Ho, W.H.3    Foster, J.4    Zhang, Z.5    Stinson, J.6    Wood, W.I.7    Goddard, A.D.8    Gurney, A.L.9
  • 31
    • 0024592945 scopus 로고
    • Molecular cloning of human intestinal mucin cDNAs. Sequence analysis and evidence for genetic polymorphism
    • Gum, J. R., J. C. Byrd, J. W. Hicks, N. W. Toribara, D. T. Lamport, and Y. S. Kim. 1989. Molecular cloning of human intestinal mucin cDNAs. Sequence analysis and evidence for genetic polymorphism. J. Biol. Chem. 264: 6480-6487.
    • (1989) J. Biol. Chem. , vol.264 , pp. 6480-6487
    • Gum, J.R.1    Byrd, J.C.2    Hicks, J.W.3    Toribara, N.W.4    Lamport, D.T.5    Kim, Y.S.6
  • 34
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11: 1475-1489.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 35
    • 0037080031 scopus 로고    scopus 로고
    • IL-6 secretion by human pancreatic periacinar myofibroblasts in response to inflammatory mediators
    • Shimada, M., A. Andoh, K. Hata, K. Tasaki, Y. Araki, Y. Fujiyama, and T. Bamba. 2002. IL-6 secretion by human pancreatic periacinar myofibroblasts in response to inflammatory mediators. J. Immunol. 168: 861-868.
    • (2002) J. Immunol. , vol.168 , pp. 861-868
    • Shimada, M.1    Andoh, A.2    Hata, K.3    Tasaki, K.4    Araki, Y.5    Fujiyama, Y.6    Bamba, T.7
  • 36
    • 0033842787 scopus 로고    scopus 로고
    • AP-1 and C/EBP transcription factors contribute to mda-7 gene promoter activity during human melanoma differentiation
    • Madireddi, M. T., P. Dent, and P. B. Fisher. 2000. AP-1 and C/EBP transcription factors contribute to mda-7 gene promoter activity during human melanoma differentiation. J. Cell Physiol. 185: 36-46.
    • (2000) J. Cell Physiol. , vol.185 , pp. 36-46
    • Madireddi, M.T.1    Dent, P.2    Fisher, P.B.3
  • 37
    • 0037103248 scopus 로고    scopus 로고
    • IL-17 selectively down-regulates TNF-α-induced RANTES gene expression in human colonic subepithelial myofibroblasts
    • Andoh, A., S. Fujino, S. Bamba, Y. Araki, T. Okuno, T. Bamba, and Y. Fujiyama. 2002. IL-17 selectively down-regulates TNF-α-induced RANTES gene expression in human colonic subepithelial myofibroblasts. J. Immunol. 169: 1683-1687.
    • (2002) J. Immunol. , vol.169 , pp. 1683-1687
    • Andoh, A.1    Fujino, S.2    Bamba, S.3    Araki, Y.4    Okuno, T.5    Bamba, T.6    Fujiyama, Y.7
  • 38
    • 0035663051 scopus 로고    scopus 로고
    • Dominant negative c-jun gene transfer inhibits vascular smooth muscle cell proliferation and neointimal hyperplasia in rats
    • Yasumoto, H., S. Kim, Y. Zhan, H. Miyazaki, M. Hoshiga, Y. Kaneda, R. Morishita, and H. Iwao. 2001. Dominant negative c-jun gene transfer inhibits vascular smooth muscle cell proliferation and neointimal hyperplasia in rats. Gene Ther. 8: 1682-1689.
    • (2001) Gene Ther. , vol.8 , pp. 1682-1689
    • Yasumoto, H.1    Kim, S.2    Zhan, Y.3    Miyazaki, H.4    Hoshiga, M.5    Kaneda, Y.6    Morishita, R.7    Iwao, H.8
  • 42
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi, D. R., A. Cuenda, P. Cohen, D. T. Dudley, and A. R. Saltiel. 1995. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270: 27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 44
    • 0028988138 scopus 로고
    • SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
    • Cuenda, A., J. Rouse, Y. N. Doza, R. Meier, P. Cohen, T. F. Gallagher, P. R. Young, and J. C. Lee. 1995. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett. 364: 229-233.
    • (1995) FEBS Lett. , vol.364 , pp. 229-233
    • Cuenda, A.1    Rouse, J.2    Doza, Y.N.3    Meier, R.4    Cohen, P.5    Gallagher, T.F.6    Young, P.R.7    Lee, J.C.8
  • 45
    • 0037192843 scopus 로고    scopus 로고
    • Identification of the critical features of a small peptide inhibitor of JNK activity
    • Barr, R. K., T. S. Kendrick, and M. A. Bogoyevitch. 2002. Identification of the critical features of a small peptide inhibitor of JNK activity. J. Biol. Chem. 277: 10987-10997.
    • (2002) J. Biol. Chem. , vol.277 , pp. 10987-10997
    • Barr, R.K.1    Kendrick, T.S.2    Bogoyevitch, M.A.3
  • 49
    • 0033568608 scopus 로고    scopus 로고
    • The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
    • Winzen, R., M. Kracht, B. Ritter, A. Wilhelm, C. Y. Chen, A. B. Shyu, M. Muller, M. Gaestel, K. Resch, and H. Holtmann. 1999. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO J. 18: 4969-4980.
    • (1999) EMBO J. , vol.18 , pp. 4969-4980
    • Winzen, R.1    Kracht, M.2    Ritter, B.3    Wilhelm, A.4    Chen, C.Y.5    Shyu, A.B.6    Muller, M.7    Gaestel, M.8    Resch, K.9    Holtmann, H.10
  • 50
    • 0032951716 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes
    • Dean, J. L., M. Brook, A. R. Clark, and J. Saklatvala. 1999. p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes. J. Biol. Chem. 274: 264-269.
    • (1999) J. Biol. Chem. , vol.274 , pp. 264-269
    • Dean, J.L.1    Brook, M.2    Clark, A.R.3    Saklatvala, J.4
  • 51
    • 33847351136 scopus 로고    scopus 로고
    • The JAK-STAT signaling pathway: Input and output integration
    • Murray, P. J. 2007. The JAK-STAT signaling pathway: input and output integration. J. Immunol. 178: 2623-2629.
    • (2007) J. Immunol. , vol.178 , pp. 2623-2629
    • Murray, P.J.1
  • 52
    • 0037452789 scopus 로고    scopus 로고
    • STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunity
    • Welte, T., S. S. Zhang, T. Wang, Z. Zhang, D. G. Hesslein, Z. Yin, A. Kano, Y. Iwamoto, E. Li, J. E. Craft, et al. 2003. STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc. Natl. Acad. Sci. USA 100: 1879-1884.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1879-1884
    • Welte, T.1    Zhang, S.S.2    Wang, T.3    Zhang, Z.4    Hesslein, D.G.5    Yin, Z.6    Kano, A.7    Iwamoto, Y.8    Li, E.9    Craft, J.E.10
  • 54
    • 58149232723 scopus 로고    scopus 로고
    • Role of STAT3 in inflammatory bowel disease
    • Sugimoto, K. 2008. Role of STAT3 in inflammatory bowel disease. World J. Gastroenterol. 14: 5110-5114.
    • (2008) World J. Gastroenterol. , vol.14 , pp. 5110-5114
    • Sugimoto, K.1
  • 56
    • 18344410191 scopus 로고    scopus 로고
    • Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo
    • Atreya, R., J. Mudter, S. Finotto, J. Mullberg, T. Jostock, S. Wirtz, M. Schutz, B. Bartsch, M. Holtmann, C. Becker, et al. 2000. Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in Crohn disease and experimental colitis in vivo. Nat. Med. 6: 583-588.
    • (2000) Nat. Med. , vol.6 , pp. 583-588
    • Atreya, R.1    Mudter, J.2    Finotto, S.3    Mullberg, J.4    Jostock, T.5    Wirtz, S.6    Schutz, M.7    Bartsch, B.8    Holtmann, M.9    Becker, C.10
  • 60
    • 34250378697 scopus 로고    scopus 로고
    • Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans
    • An, G., B. Wei, B. Xia, J. M. McDaniel, T. Ju, R. D. Cummings, J. Braun, and L. Xia. 2007. Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans. J. Exp. Med. 204: 1417-1429.
    • (2007) J. Exp. Med. , vol.204 , pp. 1417-1429
    • An, G.1    Wei, B.2    Xia, B.3    McDaniel, J.M.4    Ju, T.5    Cummings, R.D.6    Braun, J.7    Xia, L.8
  • 61
    • 33750734686 scopus 로고    scopus 로고
    • Cysteine-rich domains of muc3 intestinal mucin promote cell migration, inhibit apoptosis, and accelerate wound healing
    • Ho, S. B., L. A. Dvorak, R. E. Moor, A. C. Jacobson, M. R. Frey, J. Corredor, D. B. Polk, and L. L. Shekels. 2006. Cysteine-rich domains of muc3 intestinal mucin promote cell migration, inhibit apoptosis, and accelerate wound healing. Gastroenterology 131: 1501-1517.
    • (2006) Gastroenterology , vol.131 , pp. 1501-1517
    • Ho, S.B.1    Dvorak, L.A.2    Moor, R.E.3    Jacobson, A.C.4    Frey, M.R.5    Corredor, J.6    Polk, D.B.7    Shekels, L.L.8
  • 63
    • 17244381180 scopus 로고    scopus 로고
    • Expression of interleukin-22 in rheumatoid arthritis: Potential role as a proinflammatory cytokine
    • Ikeuchi, H., T. Kuroiwa, N. Hiramatsu, Y. Kaneko, K. Hiromura, K. Ueki, and Y. Nojima. 2005. Expression of interleukin-22 in rheumatoid arthritis: potential role as a proinflammatory cytokine. Arthritis Rheum. 52: 1037-1046.
    • (2005) Arthritis Rheum. , vol.52 , pp. 1037-1046
    • Ikeuchi, H.1    Kuroiwa, T.2    Hiramatsu, N.3    Kaneko, Y.4    Hiromura, K.5    Ueki, K.6    Nojima, Y.7
  • 64
    • 67650234634 scopus 로고    scopus 로고
    • IL-22: A two-headed cytokine in IBD?
    • Seiderer, J., and S. Brand. 2009. IL-22: a two-headed cytokine in IBD? Inflamm. Bowel Dis. 15: 473-474.
    • (2009) Inflamm. Bowel Dis. , vol.15 , pp. 473-474
    • Seiderer, J.1    Brand, S.2
  • 65
    • 54349120011 scopus 로고    scopus 로고
    • Ad-MDA-7; INGN 241: A review of preclinical and clinical experience
    • Eager, R., L. Harle, and J. Nemunaitis. 2008. Ad-MDA-7; INGN 241: a review of preclinical and clinical experience. Expert. Opin. Biol. Ther. 8: 1633-1643.
    • (2008) Expert. Opin. Biol. Ther. , vol.8 , pp. 1633-1643
    • Eager, R.1    Harle, L.2    Nemunaitis, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.