Effects of caspase-1 knockout on chronic neural recording quality and longevity: Insight into cellular and molecular mechanisms of the reactive tissue response

Biomaterials

Volumn 35, Issue 36, 2014, Pages 9620-9634

  Kozai, Takashi D Y ^a,b   Li, Xia ^a   Bodily, Lance M ^c   Caparosa, Ellen M ^c   Zenonos, Georgios A ^c   Carlisle, Diane L ^c   Friedlander, Robert M ^c   Cui, X Tracy ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b CENTER FOR THE NEURAL BASIS OF COGNITION   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Blood brain barrier; Foreign body response; Impedance; Mechanical tissue strain; Oligodendrocytes; Pericyte

Indexed keywords

CELL DEATH; ELECTRIC IMPEDANCE; ELECTROPHYSIOLOGY; ENZYME ACTIVITY; MICROELECTRODES; NEURODEGENERATIVE DISEASES; NEUROPHYSIOLOGY; PROBES; SIGNAL TO NOISE RATIO; TISSUE;

BLOOD-BRAIN BARRIER; CHRONIC NEURAL RECORDING; FOREIGN BODY RESPONSE; OLIGODENDROCYTES; PERICYTE; PROGRAMMED CELL DEATHS; REACTIVE TISSUE RESPONSE; SINGLE UNIT RECORDINGS;

MAMMALS;

INTERLEUKIN 1BETA CONVERTING ENZYME;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; ELECTROPHYSIOLOGY; GLIOSIS; IMPEDANCE; IMPLANTATION; INTRACELLULAR RECORDING; KNOCKOUT MOUSE; MALE; MICROELECTRODE; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; SCAR FORMATION; TISSUE REACTION; ADVERSE EFFECTS; ANIMAL; APOPTOSIS; BRAIN; C57BL MOUSE; CYTOLOGY; FOREIGN-BODY REACTION; GENETICS; METABOLISM; NEUROPROSTHESIS; PATHOLOGY;

MUS;

ANIMALS; APOPTOSIS; BRAIN; CASPASE 1; FOREIGN-BODY REACTION; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURAL PROSTHESES; NEURONS;

EID: 84922377069     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.08.006     Document Type: Article

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