Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities

Development

Volumn 131, Issue 8, 2004, Pages 1847-1857

  Bjarnegård, Mattias ^a   Enge, Maria ^a   Norlin, Jenny ^a   Gustafsdottir, Sigrun ^b   Fredriksson, Simon ^b   Abramsson, Alexandra ^a   Takemoto, Minoru ^a   Gustafsson, Erika ^c   Fässler, Reinhard ^d   Betsholtz, Christer ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c LUND UNIVERSITY   (Sweden)

^d MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

1oxP; Cre; Endothelium; Microaneurysm; PDGFB; Pericytes

Indexed keywords

CRE RECOMBINASE; PLATELET DERIVED GROWTH FACTOR B;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BLOOD VESSEL; BRAIN HEMORRHAGE; CELL LOSS; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC MICROANGIOPATHY; DISEASE MODEL; ENDOTHELIUM CELL; GENETIC ANALYSIS; GLOMERULONEPHRITIS; GLOMERULOPATHY; HEART DISEASE; KIDNEY DISEASE; KNOCKOUT MOUSE; LETHALITY; MOUSE; MOUSE MUTANT; NONHUMAN; NULL ALLELE; PATHOGENESIS; PATHOLOGY; PERICYTE; PLACENTA DISORDER; PRIORITY JOURNAL; SURVIVAL; VASCULAR DISEASE; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD VESSELS; BRAIN; ENDOTHELIUM; HEART DEFECTS, CONGENITAL; KIDNEY GLOMERULUS; MICE; MICE, KNOCKOUT; PERICYTES; PLACENTA; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-SIS; RECEPTOR, TIE-1;

ANIMALIA; GLOMERULUS; MAMMALIA;

EID: 2342431290     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01080     Document Type: Article

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