-
1
-
-
0035096330
-
Heterogeneity of multiple sclerosis pathogenesis: Implications for diagnosis and therapy
-
Lassmann, H., W. Bruck, and C. Lucchinetti. 2001. Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy. Trends Mol. Med. 7:115-121.
-
(2001)
Trends Mol. Med
, vol.7
, pp. 115-121
-
-
Lassmann, H.1
Bruck, W.2
Lucchinetti, C.3
-
2
-
-
16244412909
-
Multiple sclerosis: Trapped in deadly glue
-
Platten, M., and L. Steinman. 2005. Multiple sclerosis: trapped in deadly glue. Nat. Med. 11:252-253.
-
(2005)
Nat. Med
, vol.11
, pp. 252-253
-
-
Platten, M.1
Steinman, L.2
-
3
-
-
20044376483
-
Experimental autoimmune encephalomyelitis repressed by microglial paralysis
-
Heppner, F.L., M. Greter, D. Marino, J. Falsig, G. Raivich, N. Hovelmeyer, A. Waisman, T. Rulicke, M. Prinz, J. Priller, et al. 2005. Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nat. Med. 11:146-152.
-
(2005)
Nat. Med
, vol.11
, pp. 146-152
-
-
Heppner, F.L.1
Greter, M.2
Marino, D.3
Falsig, J.4
Raivich, G.5
Hovelmeyer, N.6
Waisman, A.7
Rulicke, T.8
Prinz, M.9
Priller, J.10
-
4
-
-
25444523444
-
Microglia and multiple sclerosis
-
Jack, C., F. Ruffini, A. Bar-Or, and J.P. Antel. 2005. Microglia and multiple sclerosis. J. Neurosci. Res. 81:363-373.
-
(2005)
J. Neurosci. Res
, vol.81
, pp. 363-373
-
-
Jack, C.1
Ruffini, F.2
Bar-Or, A.3
Antel, J.P.4
-
5
-
-
0344961161
-
Blood-brain barrier disruption in multiple sclerosis
-
Minagar, A., and J.S. Alexander. 2003. Blood-brain barrier disruption in multiple sclerosis. Mult. Scler. 9:540-549.
-
(2003)
Mult. Scler
, vol.9
, pp. 540-549
-
-
Minagar, A.1
Alexander, J.S.2
-
6
-
-
0024990661
-
Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis. Pathogenetic and clinical implications
-
Kermode, A.G., A.J. Thompson, P. Tofts, D.G. MacManus, B.E. Kendall, D.P. Kingsley, I.F. Moseley, P. Rudge, and W.I. McDonald. 1990. Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis. Pathogenetic and clinical implications. Brain. 113:1477-1489.
-
(1990)
Brain
, vol.113
, pp. 1477-1489
-
-
Kermode, A.G.1
Thompson, A.J.2
Tofts, P.3
MacManus, D.G.4
Kendall, B.E.5
Kingsley, D.P.6
Moseley, I.F.7
Rudge, P.8
McDonald, W.I.9
-
7
-
-
19744380563
-
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
-
Nimmerjahn, A., F. Kirchhoff, and F. Helmchen. 2005. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science. 308:1314-1318.
-
(2005)
Science
, vol.308
, pp. 1314-1318
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Helmchen, F.3
-
8
-
-
0029116712
-
Evidence of persistent blood-brain barrier abnormalities in chronic-progressive multiple sclerosis
-
Claudio, L., C.S. Raine, and C.F. Brosnan. 1995. Evidence of persistent blood-brain barrier abnormalities in chronic-progressive multiple sclerosis. Acta Neuropathol. (Berl.). 90:228-238.
-
(1995)
Acta Neuropathol. (Berl.)
, vol.90
, pp. 228-238
-
-
Claudio, L.1
Raine, C.S.2
Brosnan, C.F.3
-
9
-
-
0028089844
-
Blood-brain barrier abnormalities in longstanding multiple sclerosis lesions. An immunohistochemical study
-
Kwon, E.E., and J.W. Prineas. 1994. Blood-brain barrier abnormalities in longstanding multiple sclerosis lesions. An immunohistochemical study. J. Neuropathol. Exp. Neurol. 53:625-636.
-
(1994)
J. Neuropathol. Exp. Neurol
, vol.53
, pp. 625-636
-
-
Kwon, E.E.1
Prineas, J.W.2
-
10
-
-
0028330910
-
Immunohistochemical study of vascular injury in acute multiple sclerosis
-
Wakefield, A.J., L.J. More, J. Difford, and J.E. McLaughlin. 1994. Immunohistochemical study of vascular injury in acute multiple sclerosis. J. Clin. Pathol. 47:129-133.
-
(1994)
J. Clin. Pathol
, vol.47
, pp. 129-133
-
-
Wakefield, A.J.1
More, L.J.2
Difford, J.3
McLaughlin, J.E.4
-
11
-
-
1842367972
-
The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesion
-
Gay, F.W., T.J. Drye, G.W. Dick, and M.M. Esiri. 1997. The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesion. Brain. 120:1461-1483.
-
(1997)
Brain
, vol.120
, pp. 1461-1483
-
-
Gay, F.W.1
Drye, T.J.2
Dick, G.W.3
Esiri, M.M.4
-
12
-
-
0029918641
-
Molecular determinants of acute inflammatory responses to biomaterials
-
Tang, L., T.P. Ugarova, E.F. Plow, and J.W. Eaton. 1996. Molecular determinants of acute inflammatory responses to biomaterials. J. Clin. Invest. 97:1329-1334.
-
(1996)
J. Clin. Invest
, vol.97
, pp. 1329-1334
-
-
Tang, L.1
Ugarova, T.P.2
Plow, E.F.3
Eaton, J.W.4
-
13
-
-
0027318675
-
Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1-dependent pathway
-
Languino, L.R., J. Plescia, A. Duperray, A.A. Brian, E.F. Plow, J.E. Geltosky, and D.C. Altieri. 1993. Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1-dependent pathway. Cell. 73:1423-1434.
-
(1993)
Cell
, vol.73
, pp. 1423-1434
-
-
Languino, L.R.1
Plescia, J.2
Duperray, A.3
Brian, A.A.4
Plow, E.F.5
Geltosky, J.E.6
Altieri, D.C.7
-
14
-
-
1642333235
-
M protein, a classical bacterial virulence determinant, forms complexes with fibrinogen that induce vascular leakage
-
Herwald, H., H. Cramer, M. Morgelin, W. Russell, U. Sollenberg, A. Norrby-Teglund, H. Flodgaard, L. Lindbom, and L. Bjorck. 2004. M protein, a classical bacterial virulence determinant, forms complexes with fibrinogen that induce vascular leakage. Cell. 116:367-379.
-
(2004)
Cell
, vol.116
, pp. 367-379
-
-
Herwald, H.1
Cramer, H.2
Morgelin, M.3
Russell, W.4
Sollenberg, U.5
Norrby-Teglund, A.6
Flodgaard, H.7
Lindbom, L.8
Bjorck, L.9
-
15
-
-
85047691114
-
Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivo
-
Flick, M.J., X. Du, D.P. Witte, M. Jirouskova, D.A. Soloviev, S.J. Busuttil, E.F. Plow, and J.L. Degen. 2004. Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivo. J. Clin. Invest. 113:1596-1606.
-
(2004)
J. Clin. Invest
, vol.113
, pp. 1596-1606
-
-
Flick, M.J.1
Du, X.2
Witte, D.P.3
Jirouskova, M.4
Soloviev, D.A.5
Busuttil, S.J.6
Plow, E.F.7
Degen, J.L.8
-
16
-
-
3242690811
-
Fibrin mechanisms and functions in nervous system pathology
-
Adams, R.A., M. Passino, B.D. Sachs, T. Nuriel, and K. Akassoglou. 2004. Fibrin mechanisms and functions in nervous system pathology. Mol. Interv. 4:163-176.
-
(2004)
Mol. Interv
, vol.4
, pp. 163-176
-
-
Adams, R.A.1
Passino, M.2
Sachs, B.D.3
Nuriel, T.4
Akassoglou, K.5
-
17
-
-
10044271981
-
Fibrin(ogen)-alpha M beta 2 interactions regulate leukocyte function and innate immunity in vivo
-
Flick, M.J., X. Du, and J.L. Degen. 2004. Fibrin(ogen)-alpha M beta 2 interactions regulate leukocyte function and innate immunity in vivo. Exp. Biol. Med. (Maywood). 229:1105-1110.
-
(2004)
Exp. Biol. Med. (Maywood)
, vol.229
, pp. 1105-1110
-
-
Flick, M.J.1
Du, X.2
Degen, J.L.3
-
18
-
-
2342570412
-
Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis
-
Akassoglou, K., R.A. Adams, J. Bauer, V. Tseveleki, P. Mercado, H. Lassmann, L. Probert, and S. Strickland. 2004. Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis. Proc. Natl. Acad. Sci. USA. 101:6698-6703.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6698-6703
-
-
Akassoglou, K.1
Adams, R.A.2
Bauer, J.3
Tseveleki, V.4
Mercado, P.5
Lassmann, H.6
Probert, L.7
Strickland, S.8
-
19
-
-
0017106754
-
Experimental allergic encephalomyelitis: Role of fibrin deposition in immunopathogenesis of inflammation in rats
-
Paterson, P.Y. 1976. Experimental allergic encephalomyelitis: role of fibrin deposition in immunopathogenesis of inflammation in rats. Fed. Proc. 35:2428-2434.
-
(1976)
Fed. Proc
, vol.35
, pp. 2428-2434
-
-
Paterson, P.Y.1
-
20
-
-
0030999134
-
Platelet GPIIb/IIIa antagonists: The first anti-integrin receptor therapeutics
-
Coller, B.S. 1997. Platelet GPIIb/IIIa antagonists: the first anti-integrin receptor therapeutics. J. Clin. Invest. 99:1467-1471.
-
(1997)
J. Clin. Invest
, vol.99
, pp. 1467-1471
-
-
Coller, B.S.1
-
21
-
-
0141450468
-
Microglia and macrophage activation and the regulation of complement-receptor-3 (CR3/MAC-1)-mediated myelin phagocytosis in injury and disease
-
Rotshenker, S. 2003. Microglia and macrophage activation and the regulation of complement-receptor-3 (CR3/MAC-1)-mediated myelin phagocytosis in injury and disease. J. Mol. Neurosci. 21:65-72.
-
(2003)
J. Mol. Neurosci
, vol.21
, pp. 65-72
-
-
Rotshenker, S.1
-
22
-
-
0030297701
-
Macrophage phagocytosis of myelin in vitro determined by flow cytometry: Phagocytosis is mediated by CR3 and induces production of tumor necrosis factor-alpha and nitric oxide
-
van der Laan, L.J., S.R. Ruuls, K.S. Weber, I.J. Lodder, E.A. Dopp, and C.D. Dijkstra. 1996. Macrophage phagocytosis of myelin in vitro determined by flow cytometry: phagocytosis is mediated by CR3 and induces production of tumor necrosis factor-alpha and nitric oxide. J. Neuroimmunol. 70:145-152.
-
(1996)
J. Neuroimmunol
, vol.70
, pp. 145-152
-
-
van der Laan, L.J.1
Ruuls, S.R.2
Weber, K.S.3
Lodder, I.J.4
Dopp, E.A.5
Dijkstra, C.D.6
-
23
-
-
0034984592
-
Modulation (inhibition and augmentation) of complement receptor-3-mediated myelin phagocytosis
-
Reichert, F., U. Slobodov, C. Makranz, and S. Rotshenker. 2001. Modulation (inhibition and augmentation) of complement receptor-3-mediated myelin phagocytosis. Neurobiol. Dis. 8:504-512.
-
(2001)
Neurobiol. Dis
, vol.8
, pp. 504-512
-
-
Reichert, F.1
Slobodov, U.2
Makranz, C.3
Rotshenker, S.4
-
24
-
-
0024109978
-
Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen
-
Altieri, D.C., R. Bader, P.M. Mannucci, and T.S. Edgington. 1988. Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen. J. Cell Biol. 107:1893-1900.
-
(1988)
J. Cell Biol
, vol.107
, pp. 1893-1900
-
-
Altieri, D.C.1
Bader, R.2
Mannucci, P.M.3
Edgington, T.S.4
-
25
-
-
0037195265
-
Regulated unmasking of the cryptic binding site for integrin alpha M beta 2 in the gamma C-domain of fibrinogen
-
Lishko, V.K., B. Kudryk, V.P. Yakubenko, V.C. Yee, and T.P. Ugarova. 2002. Regulated unmasking of the cryptic binding site for integrin alpha M beta 2 in the gamma C-domain of fibrinogen. Biochemistry. 41:12942-12951.
-
(2002)
Biochemistry
, vol.41
, pp. 12942-12951
-
-
Lishko, V.K.1
Kudryk, B.2
Yakubenko, V.P.3
Yee, V.C.4
Ugarova, T.P.5
-
26
-
-
0346880066
-
Cytoskeletal remodeling in leukocyte function
-
Fenteany, G., and M. Glogauer. 2004. Cytoskeletal remodeling in leukocyte function. Curr. Opin. Hematol. 11:15-24.
-
(2004)
Curr. Opin. Hematol
, vol.11
, pp. 15-24
-
-
Fenteany, G.1
Glogauer, M.2
-
27
-
-
0036965646
-
Phagocytosis and the microtubule cytoskeleton
-
Harrison, R.E., and S. Grinstein. 2002. Phagocytosis and the microtubule cytoskeleton. Biochem. Cell Biol. 80:509-515.
-
(2002)
Biochem. Cell Biol
, vol.80
, pp. 509-515
-
-
Harrison, R.E.1
Grinstein, S.2
-
28
-
-
0034122721
-
CR3: A general purpose adhesion-recognition receptor essential for innate immunity
-
Ehlers, M.R.W. 2000. CR3: a general purpose adhesion-recognition receptor essential for innate immunity. Microbes Infect. 2:289-294.
-
(2000)
Microbes Infect
, vol.2
, pp. 289-294
-
-
Ehlers, M.R.W.1
-
29
-
-
0032575509
-
Identification of a novel recognition sequence for integrin alphaM beta2 within the gamma-chain of fibrinogen
-
Ugarova, T.P., D.A. Solovjov, L. Zhang, D.I. Loukinov, V.C. Yee, L.V. Medved, and E.F. Plow. 1998. Identification of a novel recognition sequence for integrin alphaM beta2 within the gamma-chain of fibrinogen. J. Biol. Chem. 273:22519-22527.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 22519-22527
-
-
Ugarova, T.P.1
Solovjov, D.A.2
Zhang, L.3
Loukinov, D.I.4
Yee, V.C.5
Medved, L.V.6
Plow, E.F.7
-
30
-
-
0037477629
-
Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway
-
Lehnardt, S., L. Massillon, P. Follett, F.E. Jensen, R. Ratan, P.A. Rosenberg, J.J. Volpe, and T. Vartanian. 2003. Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway. Proc. Natl. Acad. Sci. USA. 100:8514-8519.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8514-8519
-
-
Lehnardt, S.1
Massillon, L.2
Follett, P.3
Jensen, F.E.4
Ratan, R.5
Rosenberg, P.A.6
Volpe, J.J.7
Vartanian, T.8
-
31
-
-
0036548360
-
The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS
-
Lehnardt, S., C. Lachance, S. Patrizi, S. Lefebvre, P.L. Follett, F.E. Jensen, P.A. Rosenberg, J.J. Volpe, and T. Vartanian. 2002. The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS. J. Neurosci. 22:2478-2486.
-
(2002)
J. Neurosci
, vol.22
, pp. 2478-2486
-
-
Lehnardt, S.1
Lachance, C.2
Patrizi, S.3
Lefebvre, S.4
Follett, P.L.5
Jensen, F.E.6
Rosenberg, P.A.7
Volpe, J.J.8
Vartanian, T.9
-
32
-
-
0036532121
-
Roles of PI3Ks in leukocyte chemotaxis and phagocytosis
-
Stephens, L., C. Ellson, and P. Hawkins. 2002. Roles of PI3Ks in leukocyte chemotaxis and phagocytosis. Curr. Opin. Cell Biol. 14:203-213.
-
(2002)
Curr. Opin. Cell Biol
, vol.14
, pp. 203-213
-
-
Stephens, L.1
Ellson, C.2
Hawkins, P.3
-
33
-
-
0032573378
-
Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases
-
Caron, E., and A. Hall. 1998. Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. Science. 282:1717-1721.
-
(1998)
Science
, vol.282
, pp. 1717-1721
-
-
Caron, E.1
Hall, A.2
-
34
-
-
0018136199
-
The effects of ancrod, the coagulating enzyme from the venom of Malayan pit viper (A. rhodostoma) on prothrombin and fibrinogen metabolism and fibrinopeptide A release in man
-
Bell, W.R., S.S. Shapiro, J. Martinez, and H.L. Nossel. 1978. The effects of ancrod, the coagulating enzyme from the venom of Malayan pit viper (A. rhodostoma) on prothrombin and fibrinogen metabolism and fibrinopeptide A release in man. J. Lab. Clin. Med. 91:592-604.
-
(1978)
J. Lab. Clin. Med
, vol.91
, pp. 592-604
-
-
Bell, W.R.1
Shapiro, S.S.2
Martinez, J.3
Nossel, H.L.4
-
35
-
-
0037038402
-
The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease
-
Youssef, S., O. Stuve, J.C. Patarroyo, P.J. Ruiz, J.L. Radosevich, E.M. Hur, M. Bravo, D.J. Mitchell, R.A. Sobel, L. Steinman, and S.S. Zamvil. 2002. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature. 420:78-84.
-
(2002)
Nature
, vol.420
, pp. 78-84
-
-
Youssef, S.1
Stuve, O.2
Patarroyo, J.C.3
Ruiz, P.J.4
Radosevich, J.L.5
Hur, E.M.6
Bravo, M.7
Mitchell, D.J.8
Sobel, R.A.9
Steinman, L.10
Zamvil, S.S.11
-
36
-
-
0034964396
-
Recognition of fibrinogen by leukocyte integrins
-
Ugarova, T.P., and V.P. Yakubenko. 2001. Recognition of fibrinogen by leukocyte integrins. Ann. N. Y. Acad. Sci. 936:368-385.
-
(2001)
Ann. N. Y. Acad. Sci
, vol.936
, pp. 368-385
-
-
Ugarova, T.P.1
Yakubenko, V.P.2
-
37
-
-
0042573729
-
Sequence gamma 377-395(P2), but not gamma 190-202(P1), is the binding site for the alpha MI-domain of integrin alpha M beta 2 in the gamma C-domain of fibrinogen
-
Ugarova, T.P., V.K. Lishko, N.P. Podolnikova, N. Okumura, S.M. Merkulov, V.P. Yakubenko, V.C. Yee, S.T. Lord, and T.A. Haas. 2003. Sequence gamma 377-395(P2), but not gamma 190-202(P1), is the binding site for the alpha MI-domain of integrin alpha M beta 2 in the gamma C-domain of fibrinogen. Biochemistry. 42:9365-9373.
-
(2003)
Biochemistry
, vol.42
, pp. 9365-9373
-
-
Ugarova, T.P.1
Lishko, V.K.2
Podolnikova, N.P.3
Okumura, N.4
Merkulov, S.M.5
Yakubenko, V.P.6
Yee, V.C.7
Lord, S.T.8
Haas, T.A.9
-
38
-
-
2442528684
-
Intranasal administration of interferon beta bypasses the blood-brain barrier to target the central nervous system and cervical lymph nodes: A non-invasive treatment strategy for multiple sclerosis
-
Ross, T.M., P.M. Martinez, J.C. Renner, R.G. Thorne, L.R. Hanson, and W.H. Frey II. 2004. Intranasal administration of interferon beta bypasses the blood-brain barrier to target the central nervous system and cervical lymph nodes: a non-invasive treatment strategy for multiple sclerosis. J. Neuroimmunol. 151:66-77.
-
(2004)
J. Neuroimmunol
, vol.151
, pp. 66-77
-
-
Ross, T.M.1
Martinez, P.M.2
Renner, J.C.3
Thorne, R.G.4
Hanson, L.R.5
Frey II, W.H.6
-
39
-
-
0035851002
-
Nasal administration of cholera toxin (CT) suppresses clinical signs of experimental autoimmune encephalomyelitis (EAE)
-
Yura, M., I. Takahashi, S. Terawaki, T. Hiroi, M.N. Kweon, Y. Yuki, and H. Kiyono. 2001. Nasal administration of cholera toxin (CT) suppresses clinical signs of experimental autoimmune encephalomyelitis (EAE). Vaccine. 20:134-139.
-
(2001)
Vaccine
, vol.20
, pp. 134-139
-
-
Yura, M.1
Takahashi, I.2
Terawaki, S.3
Hiroi, T.4
Kweon, M.N.5
Yuki, Y.6
Kiyono, H.7
-
40
-
-
0032522119
-
Suppression of acute and protracted-relapsing experimental allergic encephalomyelitis by nasal administration of low-dose IL-10 in rats
-
Xiao, B.G., X.F. Bai, G.X. Zhang, and H. Link. 1998. Suppression of acute and protracted-relapsing experimental allergic encephalomyelitis by nasal administration of low-dose IL-10 in rats. J. Neuroimmunol. 84:230-237.
-
(1998)
J. Neuroimmunol
, vol.84
, pp. 230-237
-
-
Xiao, B.G.1
Bai, X.F.2
Zhang, G.X.3
Link, H.4
-
41
-
-
0033001779
-
Nasal administration of transforming growth factor-beta1 induces dendritic cells and inhibits protracted-relapsing experimental allergic encephalomyelitis
-
Ishikawa, M., Y. Jin, H. Guo, H. Link, and B.G. Xiao. 1999. Nasal administration of transforming growth factor-beta1 induces dendritic cells and inhibits protracted-relapsing experimental allergic encephalomyelitis. Mult. Scler. 5:184-191.
-
(1999)
Mult. Scler
, vol.5
, pp. 184-191
-
-
Ishikawa, M.1
Jin, Y.2
Guo, H.3
Link, H.4
Xiao, B.G.5
-
42
-
-
0030890185
-
Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis
-
Tran, E.H., H. Hardin-Pouzet, G. Verge, and T. Owens. 1997. Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis. J. Neuroimmunol. 74:121-129.
-
(1997)
J. Neuroimmunol
, vol.74
, pp. 121-129
-
-
Tran, E.H.1
Hardin-Pouzet, H.2
Verge, G.3
Owens, T.4
-
43
-
-
0019468319
-
The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis
-
Brosnan, C.F., M.B. Bornstein, and B.R. Bloom. 1981. The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis. J. Immunol. 126:614-620.
-
(1981)
J. Immunol
, vol.126
, pp. 614-620
-
-
Brosnan, C.F.1
Bornstein, M.B.2
Bloom, B.R.3
-
44
-
-
0019870106
-
Influence of calcium ion on the binding of fibrin amino terminal peptides to fibrinogen
-
Laudano, A.P., and R.F. Doolittle. 1981. Influence of calcium ion on the binding of fibrin amino terminal peptides to fibrinogen. Science. 212:457-459.
-
(1981)
Science
, vol.212
, pp. 457-459
-
-
Laudano, A.P.1
Doolittle, R.F.2
-
45
-
-
27744504478
-
Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis
-
Vos, C.M., J.J. Geurts, L. Montagne, E.S. van Haastert, L. Bo, P. van der Valk, F. Barkhof, and H.E. de Vries. 2005. Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis. Neurobiol. Dis. 20:953-960.
-
(2005)
Neurobiol. Dis
, vol.20
, pp. 953-960
-
-
Vos, C.M.1
Geurts, J.J.2
Montagne, L.3
van Haastert, E.S.4
Bo, L.5
van der Valk, P.6
Barkhof, F.7
de Vries, H.E.8
-
46
-
-
0036005958
-
Nervous system pathology: The fibrin perspective
-
Akassoglou, K., and S. Strickland. 2002. Nervous system pathology: the fibrin perspective. Biol. Chem. 383:37-45.
-
(2002)
Biol. Chem
, vol.383
, pp. 37-45
-
-
Akassoglou, K.1
Strickland, S.2
-
47
-
-
0345189366
-
Inflammatory blockade restores adult hippocampal neurogenesis
-
Monje, M.L., H. Toda, and T.D. Palmer. 2003. Inflammatory blockade restores adult hippocampal neurogenesis. Science. 302:1760-1765.
-
(2003)
Science
, vol.302
, pp. 1760-1765
-
-
Monje, M.L.1
Toda, H.2
Palmer, T.D.3
-
48
-
-
0033535952
-
Antibodies to CD44 and integrin alpha 4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment
-
Brocke, S., C. Piercy, L. Steinman, I.L. Weissman, and T. Veromaa. 1999. Antibodies to CD44 and integrin alpha 4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment. Proc. Natl. Acad. Sci. USA. 96:6896-6901.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6896-6901
-
-
Brocke, S.1
Piercy, C.2
Steinman, L.3
Weissman, I.L.4
Veromaa, T.5
-
49
-
-
33746903085
-
Targeting RGD recognizing integrins: Drug development, biomaterial research, tumor imaging and targeting
-
Meyer, A., J. Auernheimer, A. Modlinger, and H. Kessler. 2006. Targeting RGD recognizing integrins: drug development, biomaterial research, tumor imaging and targeting. Curr. Pharm. Des. 12:2723-2747.
-
(2006)
Curr. Pharm. Des
, vol.12
, pp. 2723-2747
-
-
Meyer, A.1
Auernheimer, J.2
Modlinger, A.3
Kessler, H.4
-
50
-
-
0029775681
-
RGD and other recognition sequences for integrins
-
Ruoslahti, E. 1996. RGD and other recognition sequences for integrins. Annu. Rev. Cell Dev. Biol. 12:697-715.
-
(1996)
Annu. Rev. Cell Dev. Biol
, vol.12
, pp. 697-715
-
-
Ruoslahti, E.1
-
51
-
-
0023637601
-
New perspectives in cell adhesion: RGD and integrins
-
Ruoslahti, E., and M.D. Pierschbacher. 1987. New perspectives in cell adhesion: RGD and integrins. Science. 238:491-497.
-
(1987)
Science
, vol.238
, pp. 491-497
-
-
Ruoslahti, E.1
Pierschbacher, M.D.2
-
52
-
-
0033152251
-
Inhibition of cell adhesion by antibodies to Arg-Gly-Asp (RGD) in normal immunoglobulin for therapeutic use (intravenous immunoglobulin, IVIg)
-
Vassilev, T.L., M.D. Kazatchkine, J.P. Van Huyen, M. Mekrache, E. Bonnin, J.C. Mani, C. Lecroubier, D. Korinth, D. Baruch, F. Schriever, and S.V. Kaveri. 1999. Inhibition of cell adhesion by antibodies to Arg-Gly-Asp (RGD) in normal immunoglobulin for therapeutic use (intravenous immunoglobulin, IVIg). Blood. 93:3624-3631.
-
(1999)
Blood
, vol.93
, pp. 3624-3631
-
-
Vassilev, T.L.1
Kazatchkine, M.D.2
Van Huyen, J.P.3
Mekrache, M.4
Bonnin, E.5
Mani, J.C.6
Lecroubier, C.7
Korinth, D.8
Baruch, D.9
Schriever, F.10
Kaveri, S.V.11
-
53
-
-
0030561019
-
Suppression of cell-transferred experimental autoimmune encephalomyelitis in defibrinated Lewis rats
-
Inoue, A., C.S. Koh, K. Shimada, N. Yanagisawa, and K. Yoshimura. 1996. Suppression of cell-transferred experimental autoimmune encephalomyelitis in defibrinated Lewis rats. J. Neuroimmunol. 71:131-137.
-
(1996)
J. Neuroimmunol
, vol.71
, pp. 131-137
-
-
Inoue, A.1
Koh, C.S.2
Shimada, K.3
Yanagisawa, N.4
Yoshimura, K.5
-
54
-
-
0036105484
-
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
-
Lock, C., G. Hermans, R. Pedotti, A. Brendolan, E. Schadt, H. Garren, A. Langer-Gould, S. Strober, B. Cannella, J. Allard, et al. 2002. Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat. Med. 8:500-508.
-
(2002)
Nat. Med
, vol.8
, pp. 500-508
-
-
Lock, C.1
Hermans, G.2
Pedotti, R.3
Brendolan, A.4
Schadt, E.5
Garren, H.6
Langer-Gould, A.7
Strober, S.8
Cannella, B.9
Allard, J.10
-
55
-
-
0026345883
-
Central nervous system endothelial cell-polymorphonuclear cell interactions during autoimmune demyelination
-
Cross, A.H., and C.S. Raine. 1991. Central nervous system endothelial cell-polymorphonuclear cell interactions during autoimmune demyelination. Am. J. Pathol. 139:1401-1409.
-
(1991)
Am. J. Pathol
, vol.139
, pp. 1401-1409
-
-
Cross, A.H.1
Raine, C.S.2
-
56
-
-
33750801864
-
A novel model of demyelinating encephalomyelitis induced by monocytes and dendritic cells
-
Furtado, G.C., B. Pina, F. Tacke, S. Gaupp, N. van Rooijen, T.M. Moran, G.J. Randolph, R.M. Ransohoff, S.W. Chensue, C.S. Raine, and S.A. Lira. 2006. A novel model of demyelinating encephalomyelitis induced by monocytes and dendritic cells. J. Immunol. 177:6871-6879.
-
(2006)
J. Immunol
, vol.177
, pp. 6871-6879
-
-
Furtado, G.C.1
Pina, B.2
Tacke, F.3
Gaupp, S.4
van Rooijen, N.5
Moran, T.M.6
Randolph, G.J.7
Ransohoff, R.M.8
Chensue, S.W.9
Raine, C.S.10
Lira, S.A.11
-
57
-
-
0026092949
-
CD11c/CD18 on neutrophils recognizes a domain at the N terminus of the A alpha chain of fibrinogen
-
Loike, J.D., B. Sodeik, L. Cao, S. Leucona, J.I. Weitz, P.A. Detmers, S.D. Wright, and S.C. Silverstein. 1991. CD11c/CD18 on neutrophils recognizes a domain at the N terminus of the A alpha chain of fibrinogen. Proc. Natl. Acad. Sci. USA. 88:1044-1048.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 1044-1048
-
-
Loike, J.D.1
Sodeik, B.2
Cao, L.3
Leucona, S.4
Weitz, J.I.5
Detmers, P.A.6
Wright, S.D.7
Silverstein, S.C.8
-
58
-
-
16244417773
-
Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
-
McMahon, E.J., S.L. Bailey, C.V. Castenada, H. Waldner, and S.D. Miller. 2005. Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis. Nat. Med. 11:335-339.
-
(2005)
Nat. Med
, vol.11
, pp. 335-339
-
-
McMahon, E.J.1
Bailey, S.L.2
Castenada, C.V.3
Waldner, H.4
Miller, S.D.5
-
59
-
-
16244380177
-
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
-
Greter, M., F.L. Heppner, M.P. Lemos, B.M. Odermatt, N. Goebels, T. Laufer, R.J. Noelle, and B. Becher. 2005. Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis. Nat. Med. 11:328-334.
-
(2005)
Nat. Med
, vol.11
, pp. 328-334
-
-
Greter, M.1
Heppner, F.L.2
Lemos, M.P.3
Odermatt, B.M.4
Goebels, N.5
Laufer, T.6
Noelle, R.J.7
Becher, B.8
-
60
-
-
33751554878
-
A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide
-
Zhou, H., B.M. Lapointe, S.R. Clark, L. Zbytnuik, and P. Kubes. 2006. A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide. J. Immunol. 177:8103-8110.
-
(2006)
J. Immunol
, vol.177
, pp. 8103-8110
-
-
Zhou, H.1
Lapointe, B.M.2
Clark, S.R.3
Zbytnuik, L.4
Kubes, P.5
-
61
-
-
0036847841
-
Microglia as liaisons between the immune and central nervous systems: Functional implications for multiple sclerosis
-
Carson, M.J. 2002. Microglia as liaisons between the immune and central nervous systems: functional implications for multiple sclerosis. Glia. 40:218-231.
-
(2002)
Glia
, vol.40
, pp. 218-231
-
-
Carson, M.J.1
-
62
-
-
0030056764
-
Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis
-
Lucchinetti, C.F., W. Bruck, M. Rodriguez, and H. Lassmann. 1996. Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis. Brain Pathol. 6:259-274.
-
(1996)
Brain Pathol
, vol.6
, pp. 259-274
-
-
Lucchinetti, C.F.1
Bruck, W.2
Rodriguez, M.3
Lassmann, H.4
-
63
-
-
33645807860
-
The macrophage in MS: Just a scavenger after all? Pathology and pathogenesis of the acute MS lesion
-
Barnett, M.H., A.P. Henderson, and J.W. Prineas. 2006. The macrophage in MS: just a scavenger after all? Pathology and pathogenesis of the acute MS lesion. Mult. Scler. 12:121-132.
-
(2006)
Mult. Scler
, vol.12
, pp. 121-132
-
-
Barnett, M.H.1
Henderson, A.P.2
Prineas, J.W.3
-
64
-
-
84882536251
-
Disease-modifying treatments in multiple sclerosis
-
G. Ebers, H. Lassmann, B. Matthews, H. Wekerle, and W.I. MacDonald, editors. Churchill Livingstone, Elsevier, Philadelphia
-
Noseworthy, J., D. Miller, and A. Compston. 2006. Disease-modifying treatments in multiple sclerosis. In McAlpine's Multiple Sclerosis. G. Ebers, H. Lassmann, B. Matthews, H. Wekerle, and W.I. MacDonald, editors. Churchill Livingstone, Elsevier, Philadelphia. 729-802.
-
(2006)
McAlpine's Multiple Sclerosis
, pp. 729-802
-
-
Noseworthy, J.1
Miller, D.2
Compston, A.3
-
65
-
-
0037075577
-
Fibrin inhibits peripheral nerve regeneration by arresting Schwann cell differentiation
-
Akassoglou, K., W.-M. Yu, P. Akpinar, and S. Strickland. 2002. Fibrin inhibits peripheral nerve regeneration by arresting Schwann cell differentiation. Neuron. 33:861-875.
-
(2002)
Neuron
, vol.33
, pp. 861-875
-
-
Akassoglou, K.1
Yu, W.-M.2
Akpinar, P.3
Strickland, S.4
-
66
-
-
3042701267
-
The neurite outgrowth inhibitor Nogo A is involved in autoimmune-mediated demyelination
-
Karnezis, T., W. Mandemakers, J.L. McQualter, B. Zheng, P.P. Ho, K.A. Jordan, B.M. Murray, B. Barres, M. Tessier-Lavigne, and C.C. Bernard. 2004. The neurite outgrowth inhibitor Nogo A is involved in autoimmune-mediated demyelination. Nat. Neurosci. 7:736-744.
-
(2004)
Nat. Neurosci
, vol.7
, pp. 736-744
-
-
Karnezis, T.1
Mandemakers, W.2
McQualter, J.L.3
Zheng, B.4
Ho, P.P.5
Jordan, K.A.6
Murray, B.M.7
Barres, B.8
Tessier-Lavigne, M.9
Bernard, C.C.10
-
67
-
-
0031659763
-
Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: Models for multiple sclerosis with primary oligodendrogliopathy
-
Akassoglou, K., J. Bauer, G. Kassiotis, M. Pasparakis, H. Lassmann, G. Kollias, and L. Probert. 1998. Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy. Am. J. Pathol. 153:801-813.
-
(1998)
Am. J. Pathol
, vol.153
, pp. 801-813
-
-
Akassoglou, K.1
Bauer, J.2
Kassiotis, G.3
Pasparakis, M.4
Lassmann, H.5
Kollias, G.6
Probert, L.7
-
68
-
-
1842687240
-
Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration
-
Akassoglou, K., B. Malester, J. Xu, L. Tessarollo, J. Rosenbluth, and M.V. Chao. 2004. Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration. Proc. Natl. Acad. Sci. USA. 101:5075-5080.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 5075-5080
-
-
Akassoglou, K.1
Malester, B.2
Xu, J.3
Tessarollo, L.4
Rosenbluth, J.5
Chao, M.V.6
-
69
-
-
0038334811
-
Cell type-specific roles for tissue plasminogen activator released by neurons or microglia after excitotoxic injury
-
Siao, C.J., S.R. Fernandez, and S.E. Tsirka. 2003. Cell type-specific roles for tissue plasminogen activator released by neurons or microglia after excitotoxic injury. J. Neurosci. 23:3234-3242.
-
(2003)
J. Neurosci
, vol.23
, pp. 3234-3242
-
-
Siao, C.J.1
Fernandez, S.R.2
Tsirka, S.E.3
-
70
-
-
5444236527
-
Rho-mediated cytoskeletal rearrangement in response to LPA is functionally antagonized by Rac1 and PIP2
-
Seasholtz, T.M., J. Radeff-Huang, S.A. Sagi, R. Matteo, J.M. Weems, A.S. Cohen, J.R. Feramisco, and J.H. Brown. 2004. Rho-mediated cytoskeletal rearrangement in response to LPA is functionally antagonized by Rac1 and PIP2. J. Neurochem. 91:501-512.
-
(2004)
J. Neurochem
, vol.91
, pp. 501-512
-
-
Seasholtz, T.M.1
Radeff-Huang, J.2
Sagi, S.A.3
Matteo, R.4
Weems, J.M.5
Cohen, A.S.6
Feramisco, J.R.7
Brown, J.H.8
|