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Volumn 1846, Issue 2, 2014, Pages 560-575

Mechanisms of intimate and long-distance cross-talk between glioma and myeloid cells: How to break a vicious cycle

Author keywords

Cross talk; Glioblastoma; Glioma associated macrophages and microglia; Immune response; Monocytes; Myeloid derived suppressor cells

Indexed keywords

ARGINASE 1; BEVACIZUMAB; CD163 ANTIGEN; CD200 ANTIGEN; CD68 ANTIGEN; COLONY STIMULATING FACTOR 1; DEXAMETHASONE; EPIDERMAL GROWTH FACTOR RECEPTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GROWTH DIFFERENTIATION FACTOR 15; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; SCATTER FACTOR; STAT1 PROTEIN; STAT3 PROTEIN; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR; VASCULOTROPIN;

EID: 84921918767     PISSN: 0304419X     EISSN: 18792561     Source Type: Journal    
DOI: 10.1016/j.bbcan.2014.10.003     Document Type: Review
Times cited : (43)

References (247)
  • 1
    • 0034612289 scopus 로고    scopus 로고
    • Glioblastoma multiforme: The terminator
    • Holland E.C. Glioblastoma multiforme: The terminator. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:6242-6244.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 6242-6244
    • Holland, E.C.1
  • 2
    • 14244265590 scopus 로고    scopus 로고
    • Epidemiology and etiology of gliomas
    • Ohgaki H., Kleihues P. Epidemiology and etiology of gliomas. Acta Neuropathol. (Berl.) 2005, 109:93-108. 10.1007/s00401-005-0991-y.
    • (2005) Acta Neuropathol. (Berl.) , vol.109 , pp. 93-108
    • Ohgaki, H.1    Kleihues, P.2
  • 3
    • 84863562673 scopus 로고    scopus 로고
    • Glioblastoma survival in the United States before and during the temozolomide era
    • Johnson D.R., O'Neill B.P. Glioblastoma survival in the United States before and during the temozolomide era. J. Neurooncol. 2012, 107:359-364. 10.1007/s11060-011-0749-4.
    • (2012) J. Neurooncol. , vol.107 , pp. 359-364
    • Johnson, D.R.1    O'Neill, B.P.2
  • 7
    • 41149117162 scopus 로고    scopus 로고
    • Immunotherapy of malignant brain tumors
    • Mitchell D.A., Fecci P.E., Sampson J.H. Immunotherapy of malignant brain tumors. Immunol. Rev. 2008, 222:70-100. 10.1111/j.1600-065X.2008.00603.x.
    • (2008) Immunol. Rev. , vol.222 , pp. 70-100
    • Mitchell, D.A.1    Fecci, P.E.2    Sampson, J.H.3
  • 8
    • 69949148057 scopus 로고    scopus 로고
    • Immunotherapy of diffuse gliomas: biological background, current status and future developments
    • Grauer O.M., Wesseling P., Adema G.J. Immunotherapy of diffuse gliomas: biological background, current status and future developments. Brain Pathol. 2009, 19:674-693. 10.1111/j.1750-3639.2009.00315.x.
    • (2009) Brain Pathol. , vol.19 , pp. 674-693
    • Grauer, O.M.1    Wesseling, P.2    Adema, G.J.3
  • 9
    • 81855175970 scopus 로고    scopus 로고
    • Immunotherapy for glioma: getting closer to the clinical arena?. [Miscellaneous Article]
    • (Dec. 2011)
    • Finocchiaro G., Pellegatta S. Immunotherapy for glioma: getting closer to the clinical arena?. [Miscellaneous Article]. Curr. Opin. Neurol. 2011, 24:641-647. (Dec. 2011). 10.1097/WCO.0b013e32834cbb17.
    • (2011) Curr. Opin. Neurol. , vol.24 , pp. 641-647
    • Finocchiaro, G.1    Pellegatta, S.2
  • 10
    • 0026521970 scopus 로고
    • Treatment of murine primary brain tumors with systemic interleukin-2 and tumor-infiltrating lymphocytes
    • Saris S.C., Spiess P., Lieberman D.M., Lin S., Walbridge S., Oldfield E.H. Treatment of murine primary brain tumors with systemic interleukin-2 and tumor-infiltrating lymphocytes. J. Neurosurg. 1992, 76:513-519. 10.3171/jns.1992.76.3.0513.
    • (1992) J. Neurosurg. , vol.76 , pp. 513-519
    • Saris, S.C.1    Spiess, P.2    Lieberman, D.M.3    Lin, S.4    Walbridge, S.5    Oldfield, E.H.6
  • 12
    • 0020507444 scopus 로고
    • Immunobiology of primary intracranial tumors. Part 7: Active immunization of patients with anaplastic human glioma cells: a pilot study
    • Mahaley M.S., Bigner D.D., Dudka L.F., Wilds P.R., Williams D.H., Bouldin T.W., et al. Immunobiology of primary intracranial tumors. Part 7: Active immunization of patients with anaplastic human glioma cells: a pilot study. J. Neurosurg. 1983, 59:201-207. 10.3171/jns.1983.59.2.0201.
    • (1983) J. Neurosurg. , vol.59 , pp. 201-207
    • Mahaley, M.S.1    Bigner, D.D.2    Dudka, L.F.3    Wilds, P.R.4    Williams, D.H.5    Bouldin, T.W.6
  • 13
    • 78651010946 scopus 로고
    • Immunity to homologous grafted skin. III. The fate of skin homographs transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye
    • Medawar P.B. Immunity to homologous grafted skin. III. The fate of skin homographs transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye. Br. J. Exp. Pathol. 1948, 29:58-69.
    • (1948) Br. J. Exp. Pathol. , vol.29 , pp. 58-69
    • Medawar, P.B.1
  • 16
    • 33845628839 scopus 로고    scopus 로고
    • What is immune privilege (not)?
    • Galea I., Bechmann I., Perry V.H. What is immune privilege (not)?. Trends Immunol. 2007, 28:12-18. 10.1016/j.it.2006.11.004.
    • (2007) Trends Immunol. , vol.28 , pp. 12-18
    • Galea, I.1    Bechmann, I.2    Perry, V.H.3
  • 17
    • 84862987260 scopus 로고    scopus 로고
    • Basic concepts in glioma immunology
    • Parney I.F. Basic concepts in glioma immunology. Adv. Exp. Med. Biol. 2012, 746:42-52. 10.1007/978-1-4614-3146-6_4.
    • (2012) Adv. Exp. Med. Biol. , vol.746 , pp. 42-52
    • Parney, I.F.1
  • 18
    • 84862994725 scopus 로고    scopus 로고
    • Mechanisms of immune evasion by gliomas
    • Springer, New York, R.Y. MD (Ed
    • Rolle C.E., Sengupta S., Lesniak M.S. Mechanisms of immune evasion by gliomas. Glioma 2012, 53-76. Springer, New York, (http://link.springer.com/chapter/10.1007/978-1-4614-3146-6_5). R.Y. MD (Ed.).
    • (2012) Glioma , pp. 53-76
    • Rolle, C.E.1    Sengupta, S.2    Lesniak, M.S.3
  • 19
    • 34547112565 scopus 로고    scopus 로고
    • WHO grade associated downregulation of MHC class I antigen-processing machinery components in human astrocytomas: does it reflect a potential immune escape mechanism?
    • Mehling M., Simon P., Mittelbronn M., Meyermann R., Ferrone S., Weller M., et al. WHO grade associated downregulation of MHC class I antigen-processing machinery components in human astrocytomas: does it reflect a potential immune escape mechanism?. Acta Neuropathol. (Berl.) 2007, 114:111-119. 10.1007/s00401-007-0231-8.
    • (2007) Acta Neuropathol. (Berl.) , vol.114 , pp. 111-119
    • Mehling, M.1    Simon, P.2    Mittelbronn, M.3    Meyermann, R.4    Ferrone, S.5    Weller, M.6
  • 20
    • 0025770177 scopus 로고
    • Characterization of the mononuclear cell infiltrate and HLA-Dr expression in 19 oligodendrogliomas
    • Rossi M.L., Esiri M.M., Jones N.R., Coakham H.B., Moss T.H., Cruz-Sanchez F.F., et al. Characterization of the mononuclear cell infiltrate and HLA-Dr expression in 19 oligodendrogliomas. Surg. Neurol. 1991, 36:119-125.
    • (1991) Surg. Neurol. , vol.36 , pp. 119-125
    • Rossi, M.L.1    Esiri, M.M.2    Jones, N.R.3    Coakham, H.B.4    Moss, T.H.5    Cruz-Sanchez, F.F.6
  • 22
    • 0036569659 scopus 로고    scopus 로고
    • A functional role of HLA-G expression in human gliomas: an alternative strategy of immune escape
    • Wiendl H., Mitsdoerffer M., Hofmeister V., Wischhusen J., Bornemann A., Meyermann R., et al. A functional role of HLA-G expression in human gliomas: an alternative strategy of immune escape. J. Immunol. 2002, 168:4772-4780.
    • (2002) J. Immunol. , vol.168 , pp. 4772-4780
    • Wiendl, H.1    Mitsdoerffer, M.2    Hofmeister, V.3    Wischhusen, J.4    Bornemann, A.5    Meyermann, R.6
  • 23
    • 0027154692 scopus 로고
    • Detection of active form of transforming growth factor-beta in cerebrospinal fluid of patients with glioma
    • Tada T., Yabu K., Kobayashi S. Detection of active form of transforming growth factor-beta in cerebrospinal fluid of patients with glioma. Jpn. J. Cancer Res. Gann 1993, 84:544-548.
    • (1993) Jpn. J. Cancer Res. Gann , vol.84 , pp. 544-548
    • Tada, T.1    Yabu, K.2    Kobayashi, S.3
  • 24
    • 0035360795 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human gliomas: prognostic significance and molecular correlations
    • Shono T., Tofilon P.J., Bruner J.M., Owolabi O., Lang F.F. Cyclooxygenase-2 expression in human gliomas: prognostic significance and molecular correlations. Cancer Res. 2001, 61:4375-4381.
    • (2001) Cancer Res. , vol.61 , pp. 4375-4381
    • Shono, T.1    Tofilon, P.J.2    Bruner, J.M.3    Owolabi, O.4    Lang, F.F.5
  • 25
    • 47949090079 scopus 로고    scopus 로고
    • The role of myeloid cells in the promotion of tumour angiogenesis
    • Murdoch C., Muthana M., Coffelt S.B., Lewis C.E. The role of myeloid cells in the promotion of tumour angiogenesis. Nat. Rev. Cancer 2008, 8:618-631. 10.1038/nrc2444.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 618-631
    • Murdoch, C.1    Muthana, M.2    Coffelt, S.B.3    Lewis, C.E.4
  • 26
    • 0030778631 scopus 로고    scopus 로고
    • Interleukin 10 is expressed in human gliomas in vivo and increases glioma cell proliferation and motility in vitro
    • Huettner C., Czub S., Kerkau S., Roggendorf W., Tonn J.C. Interleukin 10 is expressed in human gliomas in vivo and increases glioma cell proliferation and motility in vitro. Anticancer Res. 1997, 17:3217-3224.
    • (1997) Anticancer Res. , vol.17 , pp. 3217-3224
    • Huettner, C.1    Czub, S.2    Kerkau, S.3    Roggendorf, W.4    Tonn, J.C.5
  • 27
    • 84863049147 scopus 로고    scopus 로고
    • A dialog between glioma and microglia that promotes tumor invasiveness through the CCL2/CCR2/interleukin-6 axis
    • Zhang J., Sarkar S., Cua R., Zhou Y., Hader W., Yong V.W. A dialog between glioma and microglia that promotes tumor invasiveness through the CCL2/CCR2/interleukin-6 axis. Carcinogenesis 2012, 33:312-319. 10.1093/carcin/bgr289.
    • (2012) Carcinogenesis , vol.33 , pp. 312-319
    • Zhang, J.1    Sarkar, S.2    Cua, R.3    Zhou, Y.4    Hader, W.5    Yong, V.W.6
  • 28
    • 30144443269 scopus 로고    scopus 로고
    • Paradoxical roles of the immune system during cancer development
    • de Visser K.E., Eichten A., Coussens L.M. Paradoxical roles of the immune system during cancer development. Nat. Rev. Cancer 2006, 6:24-37. 10.1038/nrc1782.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 24-37
    • de Visser, K.E.1    Eichten, A.2    Coussens, L.M.3
  • 29
    • 34347267305 scopus 로고    scopus 로고
    • The 2007 Revised World Health Organization (WHO) Classification of Tumours of the Central Nervous System: newly codified entities
    • Fuller G.N., Scheithauer B.W. The 2007 Revised World Health Organization (WHO) Classification of Tumours of the Central Nervous System: newly codified entities. Brain Pathol. 2007, 17:304-307. 10.1111/j.1750-3639.2007.00084.x.
    • (2007) Brain Pathol. , vol.17 , pp. 304-307
    • Fuller, G.N.1    Scheithauer, B.W.2
  • 31
    • 14844330067 scopus 로고    scopus 로고
    • Years of life lost (YLL) from cancer is an important measure of population burden-and should be considered when allocating research funds
    • Burnet N.G., Jefferies S.J., Benson R.J., Hunt D.P., Treasure F.P. Years of life lost (YLL) from cancer is an important measure of population burden-and should be considered when allocating research funds. Br. J. Cancer 2005, 92:241-245. 10.1038/sj.bjc.6602321.
    • (2005) Br. J. Cancer , vol.92 , pp. 241-245
    • Burnet, N.G.1    Jefferies, S.J.2    Benson, R.J.3    Hunt, D.P.4    Treasure, F.P.5
  • 33
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 34
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674. 10.1016/j.cell.2011.02.013.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 35
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Verhaak R.G.W., Hoadley K.A., Purdom E., Wang V., Qi Y., Wilkerson M.D., et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010, 17:98-110. 10.1016/j.ccr.2009.12.020.
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.W.1    Hoadley, K.A.2    Purdom, E.3    Wang, V.4    Qi, Y.5    Wilkerson, M.D.6
  • 36
    • 73349142719 scopus 로고    scopus 로고
    • In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer
    • Pagès F., Kirilovsky A., Mlecnik B., Asslaber M., Tosolini M., Bindea G., et al. In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer. J. Clin. Oncol. 2009, 27:5944-5951. 10.1200/JCO.2008.19.6147.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 5944-5951
    • Pagès, F.1    Kirilovsky, A.2    Mlecnik, B.3    Asslaber, M.4    Tosolini, M.5    Bindea, G.6
  • 37
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • Galon J., Costes A., Sanchez-Cabo F., Kirilovsky A., Mlecnik B., Lagorce-Pagès C., et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006, 313:1960-1964. 10.1126/science.1129139.
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3    Kirilovsky, A.4    Mlecnik, B.5    Lagorce-Pagès, C.6
  • 38
    • 84855225492 scopus 로고    scopus 로고
    • The immune score as a new possible approach for the classification of cancer
    • Galon J., Pagès F., Marincola F.M., Thurin M., Trinchieri G., Fox B.A., et al. The immune score as a new possible approach for the classification of cancer. J. Transl. Med. 2012, 10:1. 10.1186/1479-5876-10-1.
    • (2012) J. Transl. Med. , vol.10 , pp. 1
    • Galon, J.1    Pagès, F.2    Marincola, F.M.3    Thurin, M.4    Trinchieri, G.5    Fox, B.A.6
  • 39
    • 84890280907 scopus 로고    scopus 로고
    • Towards the introduction of the "Immunoscore" in the classification of malignant tumours
    • Galon J., Mlecnik B., Bindea G., Angell H.K., Berger A., Lagorce C., et al. Towards the introduction of the "Immunoscore" in the classification of malignant tumours. J. Pathol. 2014, 232:199-209. 10.1002/path.4287.
    • (2014) J. Pathol. , vol.232 , pp. 199-209
    • Galon, J.1    Mlecnik, B.2    Bindea, G.3    Angell, H.K.4    Berger, A.5    Lagorce, C.6
  • 40
    • 84886774000 scopus 로고    scopus 로고
    • Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level
    • Kmiecik J., Poli A., Brons N.H.C., Waha A., Eide G.E., Enger P.Ø., et al. Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level. J. Neuroimmunol. 2013, 264:71-83. 10.1016/j.jneuroim.2013.08.013.
    • (2013) J. Neuroimmunol. , vol.264 , pp. 71-83
    • Kmiecik, J.1    Poli, A.2    Brons, N.H.C.3    Waha, A.4    Eide, G.E.5    Enger, P.Ø.6
  • 41
    • 0034093158 scopus 로고    scopus 로고
    • Flow cytometric characterization of tumor-associated macrophages in experimental gliomas
    • (discussion 961-962)
    • Badie B., Schartner J.M. Flow cytometric characterization of tumor-associated macrophages in experimental gliomas. Neurosurgery 2000, 46:957-961. (discussion 961-962).
    • (2000) Neurosurgery , vol.46 , pp. 957-961
    • Badie, B.1    Schartner, J.M.2
  • 42
    • 0029781336 scopus 로고    scopus 로고
    • Distribution and characterization of microglia/macrophages in human brain tumors
    • Roggendorf W., Strupp S., Paulus W. Distribution and characterization of microglia/macrophages in human brain tumors. Acta Neuropathol. (Berl.) 1996, 92:288-293.
    • (1996) Acta Neuropathol. (Berl.) , vol.92 , pp. 288-293
    • Roggendorf, W.1    Strupp, S.2    Paulus, W.3
  • 43
    • 84881151730 scopus 로고    scopus 로고
    • Glioma grade is associated with the accumulation and activity of cells bearing M2 monocyte markers
    • Prosniak M., Harshyne L.A., Andrews D.W., Kenyon L.C., Bedelbaeva K., Apanasovich T.V., et al. Glioma grade is associated with the accumulation and activity of cells bearing M2 monocyte markers. Clin. Cancer Res. 2013, 19:3776-3786. 10.1158/1078-0432.CCR-12-1940.
    • (2013) Clin. Cancer Res. , vol.19 , pp. 3776-3786
    • Prosniak, M.1    Harshyne, L.A.2    Andrews, D.W.3    Kenyon, L.C.4    Bedelbaeva, K.5    Apanasovich, T.V.6
  • 45
    • 34250796207 scopus 로고    scopus 로고
    • Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry
    • Ahmed Z., Shaw G., Sharma V.P., Yang C., McGowan E., Dickson D.W. Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry. J. Histochem. Cytochem. 2007, 55:687-700. 10.1369/jhc.6A7156.2007.
    • (2007) J. Histochem. Cytochem. , vol.55 , pp. 687-700
    • Ahmed, Z.1    Shaw, G.2    Sharma, V.P.3    Yang, C.4    McGowan, E.5    Dickson, D.W.6
  • 46
    • 17744388105 scopus 로고    scopus 로고
    • Down-regulation of the macrophage lineage through interaction with OX2 (CD200)
    • Hoek R.M., Ruuls S.R., Murphy C.A., Wright G.J., Goddard R., Zurawski S.M., et al. Down-regulation of the macrophage lineage through interaction with OX2 (CD200). Science 2000, 290:1768-1771.
    • (2000) Science , vol.290 , pp. 1768-1771
    • Hoek, R.M.1    Ruuls, S.R.2    Murphy, C.A.3    Wright, G.J.4    Goddard, R.5    Zurawski, S.M.6
  • 47
    • 84881504052 scopus 로고    scopus 로고
    • The controversial role of microglia in malignant gliomas
    • Wei J., Gabrusiewicz K., Heimberger A. The controversial role of microglia in malignant gliomas. Clin. Dev. Immunol. 2013, 2013. 10.1155/2013/285246.
    • (2013) Clin. Dev. Immunol. , vol.2013
    • Wei, J.1    Gabrusiewicz, K.2    Heimberger, A.3
  • 48
    • 0029002659 scopus 로고
    • Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared
    • Ford A.L., Goodsall A.L., Hickey W.F., Sedgwick J.D. Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared. J. Immunol. 1995, 154:4309-4321.
    • (1995) J. Immunol. , vol.154 , pp. 4309-4321
    • Ford, A.L.1    Goodsall, A.L.2    Hickey, W.F.3    Sedgwick, J.D.4
  • 49
    • 78149360132 scopus 로고    scopus 로고
    • Fate mapping analysis reveals that adult microglia derive from primitive macrophages
    • Ginhoux F., Greter M., Leboeuf M., Nandi S., See P., Gokhan S., et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 2010, 330:841-845. 10.1126/science.1194637.
    • (2010) Science , vol.330 , pp. 841-845
    • Ginhoux, F.1    Greter, M.2    Leboeuf, M.3    Nandi, S.4    See, P.5    Gokhan, S.6
  • 50
    • 84902537095 scopus 로고    scopus 로고
    • Phagocytosis of microglia in the central nervous system diseases
    • Fu R., Shen Q., Xu P., Luo J.J., Tang Y. Phagocytosis of microglia in the central nervous system diseases. Mol. Neurobiol. 2014, 49:1422-1434. 10.1007/s12035-013-8620-6.
    • (2014) Mol. Neurobiol. , vol.49 , pp. 1422-1434
    • Fu, R.1    Shen, Q.2    Xu, P.3    Luo, J.J.4    Tang, Y.5
  • 51
    • 77950858637 scopus 로고    scopus 로고
    • Microglia in neurodegenerative disease
    • Perry V.H., Nicoll J.A.R., Holmes C. Microglia in neurodegenerative disease. Nat. Rev. Neurol. 2010, 6:193-201. 10.1038/nrneurol.2010.17.
    • (2010) Nat. Rev. Neurol. , vol.6 , pp. 193-201
    • Perry, V.H.1    Nicoll, J.A.R.2    Holmes, C.3
  • 52
    • 4644232615 scopus 로고    scopus 로고
    • Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs
    • Olson J.K., Miller S.D. Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs. J. Immunol. 2004, 173:3916-3924.
    • (2004) J. Immunol. , vol.173 , pp. 3916-3924
    • Olson, J.K.1    Miller, S.D.2
  • 53
    • 33748532939 scopus 로고    scopus 로고
    • The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses
    • Hussain S.F., Yang D., Suki D., Aldape K., Grimm E., Heimberger A.B. The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses. Neuro-Oncology 2006, 8:261-279. 10.1215/15228517-2006-008.
    • (2006) Neuro-Oncology , vol.8 , pp. 261-279
    • Hussain, S.F.1    Yang, D.2    Suki, D.3    Aldape, K.4    Grimm, E.5    Heimberger, A.B.6
  • 54
    • 77954641353 scopus 로고    scopus 로고
    • Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties
    • Rodrigues J.C., Gonzalez G.C., Zhang L., Ibrahim G., Kelly J.J., Gustafson M.P., et al. Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties. Neuro-Oncology 2010, 12:351-365. 10.1093/neuonc/nop023.
    • (2010) Neuro-Oncology , vol.12 , pp. 351-365
    • Rodrigues, J.C.1    Gonzalez, G.C.2    Zhang, L.3    Ibrahim, G.4    Kelly, J.J.5    Gustafson, M.P.6
  • 55
    • 84868092714 scopus 로고    scopus 로고
    • Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells
    • Varvel N.H., Grathwohl S.A., Baumann F., Liebig C., Bosch A., Brawek B., et al. Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:18150-18155. 10.1073/pnas.1210150109.
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 18150-18155
    • Varvel, N.H.1    Grathwohl, S.A.2    Baumann, F.3    Liebig, C.4    Bosch, A.5    Brawek, B.6
  • 58
    • 79960003585 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma
    • Raychaudhuri B., Rayman P., Ireland J., Ko J., Rini B., Borden E.C., et al. Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma. Neuro-Oncology 2011, 13:591-599. 10.1093/neuonc/nor042.
    • (2011) Neuro-Oncology , vol.13 , pp. 591-599
    • Raychaudhuri, B.1    Rayman, P.2    Ireland, J.3    Ko, J.4    Rini, B.5    Borden, E.C.6
  • 59
    • 84866378995 scopus 로고    scopus 로고
    • The RCAS/TV - a model of murine glioma reproduces immunosuppression produced by myeloid-derived suppressor cells in humans with GBM
    • Raychaudhuri B., Vogelbaum M.A. The RCAS/TV - a model of murine glioma reproduces immunosuppression produced by myeloid-derived suppressor cells in humans with GBM. Neuro-Oncology 2011, 13:iii30-iii33. 10.1093/neuonc/nor150.
    • (2011) Neuro-Oncology , vol.13 , pp. 330-333
    • Raychaudhuri, B.1    Vogelbaum, M.A.2
  • 60
    • 65249138393 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: Linking inflammation and cancer
    • Ostrand-Rosenberg S., Sinha P. Myeloid-derived suppressor cells: Linking inflammation and cancer. J. Immunol. 2009, 182:4499-4506. 10.4049/jimmunol.0802740.
    • (2009) J. Immunol. , vol.182 , pp. 4499-4506
    • Ostrand-Rosenberg, S.1    Sinha, P.2
  • 62
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • Youn J.-I., Nagaraj S., Collazo M., Gabrilovich D.I. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J. Immunol. 2008, 181:5791-5802.
    • (2008) J. Immunol. , vol.181 , pp. 5791-5802
    • Youn, J.-I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 63
    • 34247871227 scopus 로고    scopus 로고
    • Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion
    • Dietlin T.A., Hofman F.M., Lund B.T., Gilmore W., Stohlman S.A., van der Veen R.C. Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion. J. Leukoc. Biol. 2007, 81:1205-1212. 10.1189/jlb.1006640.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 1205-1212
    • Dietlin, T.A.1    Hofman, F.M.2    Lund, B.T.3    Gilmore, W.4    Stohlman, S.A.5    van der Veen, R.C.6
  • 64
    • 84870892487 scopus 로고    scopus 로고
    • CD11b+Ly6C++Ly6G- cells show distinct function in mice with chronic inflammation or tumor burden
    • Källberg E., Stenström M., Liberg D., Ivars F., Leanderson T. CD11b+Ly6C++Ly6G- cells show distinct function in mice with chronic inflammation or tumor burden. BMC Immunol. 2012, 13:69. 10.1186/1471-2172-13-69.
    • (2012) BMC Immunol. , vol.13 , pp. 69
    • Källberg, E.1    Stenström, M.2    Liberg, D.3    Ivars, F.4    Leanderson, T.5
  • 65
    • 84867909619 scopus 로고    scopus 로고
    • Mouse CD11b+Gr-1+ myeloid cells can promote Th17 cell differentiation and experimental autoimmune encephalomyelitis
    • Yi H., Guo C., Yu X., Zuo D., Wang X.-Y. Mouse CD11b+Gr-1+ myeloid cells can promote Th17 cell differentiation and experimental autoimmune encephalomyelitis. J. Immunol. 2012, 189:4295-4304. 10.4049/jimmunol.1200086.
    • (2012) J. Immunol. , vol.189 , pp. 4295-4304
    • Yi, H.1    Guo, C.2    Yu, X.3    Zuo, D.4    Wang, X.-Y.5
  • 66
    • 78649586268 scopus 로고    scopus 로고
    • The biology of myeloid-derived suppressor cells: The blessing and the curse of morphological and functional heterogeneity
    • Youn J.-I., Gabrilovich D.I. The biology of myeloid-derived suppressor cells: The blessing and the curse of morphological and functional heterogeneity. Eur. J. Immunol. 2010, 40:2969-2975. 10.1002/eji.201040895.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 2969-2975
    • Youn, J.-I.1    Gabrilovich, D.I.2
  • 68
    • 84886943326 scopus 로고    scopus 로고
    • Remote control of macrophage production by cancer
    • Cortez-Retamozo V., Engblom C., Pittet M.J. Remote control of macrophage production by cancer. Oncoimmunology 2013, 2:e24183. 10.4161/onci.24183.
    • (2013) Oncoimmunology , vol.2 , pp. e24183
    • Cortez-Retamozo, V.1    Engblom, C.2    Pittet, M.J.3
  • 69
    • 84891441830 scopus 로고    scopus 로고
    • Microglia and macrophages in malignant gliomas: Recent discoveries and implications for promising therapies
    • Carvalho da Fonseca A.C., Badie B. Microglia and macrophages in malignant gliomas: Recent discoveries and implications for promising therapies. Clin. Dev. Immunol. 2013, 2013. 10.1155/2013/264124.
    • (2013) Clin. Dev. Immunol. , vol.2013
    • Carvalho da Fonseca, A.C.1    Badie, B.2
  • 70
    • 0041835842 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 increases microglial infiltration and aggressiveness of gliomas
    • Platten M., Kretz A., Naumann U., Aulwurm S., Egashira K., Isenmann S., et al. Monocyte chemoattractant protein-1 increases microglial infiltration and aggressiveness of gliomas. Ann. Neurol. 2003, 54:388-392. 10.1002/ana.10679.
    • (2003) Ann. Neurol. , vol.54 , pp. 388-392
    • Platten, M.1    Kretz, A.2    Naumann, U.3    Aulwurm, S.4    Egashira, K.5    Isenmann, S.6
  • 71
    • 0030951515 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 expression and macrophage infiltration in gliomas
    • Leung S.Y., Wong M.P., Chung L.P., Chan A.S., Yuen S.T. Monocyte chemoattractant protein-1 expression and macrophage infiltration in gliomas. Acta Neuropathol. (Berl.) 1997, 93:518-527.
    • (1997) Acta Neuropathol. (Berl.) , vol.93 , pp. 518-527
    • Leung, S.Y.1    Wong, M.P.2    Chung, L.P.3    Chan, A.S.4    Yuen, S.T.5
  • 73
    • 0032931667 scopus 로고    scopus 로고
    • In vitro modulation of microglia motility by glioma cells is mediated by hepatocyte growth factor/scatter factor
    • (discussion 1082-1083)
    • Badie B., Schartner J., Klaver J., Vorpahl J. In vitro modulation of microglia motility by glioma cells is mediated by hepatocyte growth factor/scatter factor. Neurosurgery 1999, 44:1077-1082. (discussion 1082-1083).
    • (1999) Neurosurgery , vol.44 , pp. 1077-1082
    • Badie, B.1    Schartner, J.2    Klaver, J.3    Vorpahl, J.4
  • 74
    • 84855251694 scopus 로고    scopus 로고
    • Tumor-secreted SDF-1 promotes glioma invasiveness and TAM tropism toward hypoxia in a murine astrocytoma model
    • Wang S.-C., Hong J.-H., Hsueh C., Chiang C.-S. Tumor-secreted SDF-1 promotes glioma invasiveness and TAM tropism toward hypoxia in a murine astrocytoma model. Lab. Invest. 2012, 92:151-162. 10.1038/labinvest.2011.128.
    • (2012) Lab. Invest. , vol.92 , pp. 151-162
    • Wang, S.-C.1    Hong, J.-H.2    Hsueh, C.3    Chiang, C.-S.4
  • 75
    • 84887481716 scopus 로고    scopus 로고
    • CSF-1R inhibition alters macrophage polarization and blocks glioma progression
    • Pyonteck S.M., Akkari L., Schuhmacher A.J., Bowman R.L., Sevenich L., Quail D.F., et al. CSF-1R inhibition alters macrophage polarization and blocks glioma progression. Nat. Med. 2013, 19:1264-1272. 10.1038/nm.3337.
    • (2013) Nat. Med. , vol.19 , pp. 1264-1272
    • Pyonteck, S.M.1    Akkari, L.2    Schuhmacher, A.J.3    Bowman, R.L.4    Sevenich, L.5    Quail, D.F.6
  • 76
    • 18144406858 scopus 로고    scopus 로고
    • Tumor necrosis factor reduces brain tumor growth by enhancing macrophage recruitment and microcyst formation
    • Villeneuve J., Tremblay P., Vallières L. Tumor necrosis factor reduces brain tumor growth by enhancing macrophage recruitment and microcyst formation. Cancer Res. 2005, 65:3928-3936. 10.1158/0008-5472.CAN-04-3612.
    • (2005) Cancer Res. , vol.65 , pp. 3928-3936
    • Villeneuve, J.1    Tremblay, P.2    Vallières, L.3
  • 77
    • 0036849437 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces chemotaxis and proliferation of microglial cells
    • Forstreuter F., Lucius R., Mentlein R. Vascular endothelial growth factor induces chemotaxis and proliferation of microglial cells. J. Neuroimmunol. 2002, 132:93-98.
    • (2002) J. Neuroimmunol. , vol.132 , pp. 93-98
    • Forstreuter, F.1    Lucius, R.2    Mentlein, R.3
  • 78
    • 84864709456 scopus 로고    scopus 로고
    • The molecular profile of microglia under the influence of glioma
    • Li W., Graeber M.B. The molecular profile of microglia under the influence of glioma. Neuro-Oncology 2012, 14:958-978. 10.1093/neuonc/nos116.
    • (2012) Neuro-Oncology , vol.14 , pp. 958-978
    • Li, W.1    Graeber, M.B.2
  • 79
    • 84878811407 scopus 로고    scopus 로고
    • Distinct roles of CSF family cytokines in macrophage infiltration and activation in glioma progression and injury response
    • Sielska M., Przanowski P., Wylot B., Gabrusiewicz K., Maleszewska M., Kijewska M., et al. Distinct roles of CSF family cytokines in macrophage infiltration and activation in glioma progression and injury response. J. Pathol. 2013, 230:310-321. 10.1002/path.4192.
    • (2013) J. Pathol. , vol.230 , pp. 310-321
    • Sielska, M.1    Przanowski, P.2    Wylot, B.3    Gabrusiewicz, K.4    Maleszewska, M.5    Kijewska, M.6
  • 80
    • 84881087399 scopus 로고    scopus 로고
    • Radiation therapy-induced tumor invasiveness is associated with SDF-1-regulated macrophage mobilization and vasculogenesis
    • Wang S.-C., Yu C.-F., Hong J.-H., Tsai C.-S., Chiang C.-S. Radiation therapy-induced tumor invasiveness is associated with SDF-1-regulated macrophage mobilization and vasculogenesis. PLoS One 2013, 8:e69182. 10.1371/journal.pone.0069182.
    • (2013) PLoS One , vol.8 , pp. e69182
    • Wang, S.-C.1    Yu, C.-F.2    Hong, J.-H.3    Tsai, C.-S.4    Chiang, C.-S.5
  • 81
    • 79952250124 scopus 로고    scopus 로고
    • Glioma-initiating cells: a predominant role in microglia/macrophages tropism to glioma
    • Yi L., Xiao H., Xu M., Ye X., Hu J., Li F., et al. Glioma-initiating cells: a predominant role in microglia/macrophages tropism to glioma. J. Neuroimmunol. 2011, 232:75-82. 10.1016/j.jneuroim.2010.10.011.
    • (2011) J. Neuroimmunol. , vol.232 , pp. 75-82
    • Yi, L.1    Xiao, H.2    Xu, M.3    Ye, X.4    Hu, J.5    Li, F.6
  • 82
    • 78049270536 scopus 로고    scopus 로고
    • Glioma cancer stem cells induce immunosuppressive macrophages/microglia
    • Wu A., Wei J., Kong L.-Y., Wang Y., Priebe W., Qiao W., et al. Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro-Oncology 2010, 12:1113-1125. 10.1093/neuonc/noq082.
    • (2010) Neuro-Oncology , vol.12 , pp. 1113-1125
    • Wu, A.1    Wei, J.2    Kong, L.-Y.3    Wang, Y.4    Priebe, W.5    Qiao, W.6
  • 83
    • 84893770485 scopus 로고    scopus 로고
    • Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells
    • Sarkar S., Döring A., Zemp F.J., Silva C., Lun X., Wang X., et al. Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells. Nat. Neurosci. 2014, 17:46-55. 10.1038/nn.3597.
    • (2014) Nat. Neurosci. , vol.17 , pp. 46-55
    • Sarkar, S.1    Döring, A.2    Zemp, F.J.3    Silva, C.4    Lun, X.5    Wang, X.6
  • 84
    • 80052069274 scopus 로고    scopus 로고
    • Characteristics of the alternative phenotype of microglia/macrophages and its modulation in experimental gliomas
    • Gabrusiewicz K., Ellert-Miklaszewska A., Lipko M., Sielska M., Frankowska M., Kaminska B. Characteristics of the alternative phenotype of microglia/macrophages and its modulation in experimental gliomas. PLoS One 2011, 6:e23902. 10.1371/journal.pone.0023902.
    • (2011) PLoS One , vol.6 , pp. e23902
    • Gabrusiewicz, K.1    Ellert-Miklaszewska, A.2    Lipko, M.3    Sielska, M.4    Frankowska, M.5    Kaminska, B.6
  • 86
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: active sensor and versatile effector cells in the normal and pathologic brain
    • Hanisch U.-K., Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat. Neurosci. 2007, 10:1387-1394. 10.1038/nn1997.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1387-1394
    • Hanisch, U.-K.1    Kettenmann, H.2
  • 87
    • 50249144131 scopus 로고    scopus 로고
    • Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas
    • Komohara Y., Ohnishi K., Kuratsu J., Takeya M. Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas. J. Pathol. 2008, 216:15-24. 10.1002/path.2370.
    • (2008) J. Pathol. , vol.216 , pp. 15-24
    • Komohara, Y.1    Ohnishi, K.2    Kuratsu, J.3    Takeya, M.4
  • 90
    • 84861747362 scopus 로고    scopus 로고
    • M2 macrophage/microglial cells induce activation of Stat3 in primary central nervous system lymphoma
    • Komohara Y., Horlad H., Ohnishi K., Ohta K., Makino K., Hondo H., et al. M2 macrophage/microglial cells induce activation of Stat3 in primary central nervous system lymphoma. J. Clin. Exp. Hematopathol. 2011, 51:93-99.
    • (2011) J. Clin. Exp. Hematopathol. , vol.51 , pp. 93-99
    • Komohara, Y.1    Horlad, H.2    Ohnishi, K.3    Ohta, K.4    Makino, K.5    Hondo, H.6
  • 91
    • 80355146399 scopus 로고    scopus 로고
    • Transcriptional regulation of macrophage polarization: enabling diversity with identity
    • Lawrence T., Natoli G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat. Rev. Immunol. 2011, 11:750-761. 10.1038/nri3088.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 750-761
    • Lawrence, T.1    Natoli, G.2
  • 92
    • 84870657385 scopus 로고    scopus 로고
    • Importance of direct macrophage - Tumor cell interaction on progression of human glioma
    • Komohara Y., Horlad H., Ohnishi K., Fujiwara Y., Bai B., Nakagawa T., et al. Importance of direct macrophage - Tumor cell interaction on progression of human glioma. Cancer Sci. 2012, 103:2165-2172. 10.1111/cas.12015.
    • (2012) Cancer Sci. , vol.103 , pp. 2165-2172
    • Komohara, Y.1    Horlad, H.2    Ohnishi, K.3    Fujiwara, Y.4    Bai, B.5    Nakagawa, T.6
  • 93
    • 84921895489 scopus 로고    scopus 로고
    • S100B attenuates microglia activation in gliomas: possible role for STAT3 pathway
    • Zhang L., Liu W., Alizadeh D., Zhao D., Farrukh O., Badie B. S100B attenuates microglia activation in gliomas: possible role for STAT3 pathway. Neuro-Oncology 2010, 12:iv29-iv32. 10.1093/neuonc/noq116.s4.
    • (2010) Neuro-Oncology , vol.12 , pp. iv29-iv32
    • Zhang, L.1    Liu, W.2    Alizadeh, D.3    Zhao, D.4    Farrukh, O.5    Badie, B.6
  • 96
    • 84880772300 scopus 로고    scopus 로고
    • MicroRNA-mediated control of macrophages and its implications for cancer
    • Squadrito M.L., Etzrodt M., De Palma M., Pittet M.J. MicroRNA-mediated control of macrophages and its implications for cancer. Trends Immunol. 2013, 34:350-359. 10.1016/j.it.2013.02.003.
    • (2013) Trends Immunol. , vol.34 , pp. 350-359
    • Squadrito, M.L.1    Etzrodt, M.2    De Palma, M.3    Pittet, M.J.4
  • 97
    • 84861148197 scopus 로고    scopus 로고
    • Regulation of monocyte functional heterogeneity by miR-146a and Relb
    • Etzrodt M., Cortez-Retamozo V., Newton A., Zhao J., Ng A., Wildgruber M., et al. Regulation of monocyte functional heterogeneity by miR-146a and Relb. Cell Rep. 2012, 1:317-324. 10.1016/j.celrep.2012.02.009.
    • (2012) Cell Rep. , vol.1 , pp. 317-324
    • Etzrodt, M.1    Cortez-Retamozo, V.2    Newton, A.3    Zhao, J.4    Ng, A.5    Wildgruber, M.6
  • 98
    • 84878023280 scopus 로고    scopus 로고
    • Molecular pathways: tumor-derived microvesicles and their interactions with immune cells in vivo
    • Pucci F., Pittet M.J. Molecular pathways: tumor-derived microvesicles and their interactions with immune cells in vivo. Clin. Cancer Res. 2013, 19:2598-2604. 10.1158/1078-0432.CCR-12-0962.
    • (2013) Clin. Cancer Res. , vol.19 , pp. 2598-2604
    • Pucci, F.1    Pittet, M.J.2
  • 100
    • 43049139913 scopus 로고    scopus 로고
    • Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells
    • Al-Nedawi K., Meehan B., Micallef J., Lhotak V., May L., Guha A., et al. Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells. Nat. Cell Biol. 2008, 10:619-624. 10.1038/ncb1725.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 619-624
    • Al-Nedawi, K.1    Meehan, B.2    Micallef, J.3    Lhotak, V.4    May, L.5    Guha, A.6
  • 101
    • 70349097179 scopus 로고    scopus 로고
    • Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice
    • Zhang L., Alizadeh D., Van Handel M., Kortylewski M., Yu H., Badie B. Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice. Glia 2009, 57:1458-1467. 10.1002/glia.20863.
    • (2009) Glia , vol.57 , pp. 1458-1467
    • Zhang, L.1    Alizadeh, D.2    Van Handel, M.3    Kortylewski, M.4    Yu, H.5    Badie, B.6
  • 102
    • 0028807156 scopus 로고
    • Human glioma-derived interleukin-10 inhibits antitumor immune responses in vitro. [miscellaneous article]
    • (Dec. 1995)
    • Hishii M., Nitta T., Ishida H., Ebato M., Kurosu A., Yagita H., et al. Human glioma-derived interleukin-10 inhibits antitumor immune responses in vitro. [miscellaneous article]. Neurosurgery 1995, 37:1160-1167. (Dec. 1995).
    • (1995) Neurosurgery , vol.37 , pp. 1160-1167
    • Hishii, M.1    Nitta, T.2    Ishida, H.3    Ebato, M.4    Kurosu, A.5    Yagita, H.6
  • 103
    • 0028215961 scopus 로고
    • Antigen presentation in the central nervous system. The inhibitory effect of IL-10 on MHC class II expression and production of cytokines depends on the inducing signals and the type of cell analyzed.
    • Frei K., Lins H., Schwerdel C., Fontana A. Antigen presentation in the central nervous system. The inhibitory effect of IL-10 on MHC class II expression and production of cytokines depends on the inducing signals and the type of cell analyzed. J. Immunol. 1994, 152:2720-2728.
    • (1994) J. Immunol. , vol.152 , pp. 2720-2728
    • Frei, K.1    Lins, H.2    Schwerdel, C.3    Fontana, A.4
  • 104
    • 0032522113 scopus 로고    scopus 로고
    • Diminished monocytic HLA-DR expression and ex vivo cytokine secretion capacity in patients with glioblastoma: effect of tumor extirpation
    • Woiciechowsky C., Asadullah K., Nestler D., Schöning B., Glöckner F., Döcke W.D., et al. Diminished monocytic HLA-DR expression and ex vivo cytokine secretion capacity in patients with glioblastoma: effect of tumor extirpation. J. Neuroimmunol. 1998, 84:164-171.
    • (1998) J. Neuroimmunol. , vol.84 , pp. 164-171
    • Woiciechowsky, C.1    Asadullah, K.2    Nestler, D.3    Schöning, B.4    Glöckner, F.5    Döcke, W.D.6
  • 105
    • 77649182786 scopus 로고    scopus 로고
    • Production of immune-modulatory nonclassical molecules HLA-G and HLA-E by tumor infiltrating ameboid microglia/macrophages in glioblastomas: a role in innate immunity?
    • Kren L., Muckova K., Lzicarova E., Sova M., Vybihal V., Svoboda T., et al. Production of immune-modulatory nonclassical molecules HLA-G and HLA-E by tumor infiltrating ameboid microglia/macrophages in glioblastomas: a role in innate immunity?. J. Neuroimmunol. 2010, 220:131-135. 10.1016/j.jneuroim.2010.01.014.
    • (2010) J. Neuroimmunol. , vol.220 , pp. 131-135
    • Kren, L.1    Muckova, K.2    Lzicarova, E.3    Sova, M.4    Vybihal, V.5    Svoboda, T.6
  • 106
    • 0028876151 scopus 로고
    • T-cell costimulatory molecules B7-1 (CD80) and B7-2 (CD86) are expressed in human microglia but not in astrocytes in culture
    • Satoh J., Lee Y.B., Kim S.U. T-cell costimulatory molecules B7-1 (CD80) and B7-2 (CD86) are expressed in human microglia but not in astrocytes in culture. Brain Res. 1995, 704:92-96.
    • (1995) Brain Res. , vol.704 , pp. 92-96
    • Satoh, J.1    Lee, Y.B.2    Kim, S.U.3
  • 107
    • 0033579382 scopus 로고    scopus 로고
    • Microglial activation resulting from CD40-CD40L interaction after β-amyloid stimulation
    • Tan J., Town T., Paris D., Mori T., Suo Z., Crawford F., et al. Microglial activation resulting from CD40-CD40L interaction after β-amyloid stimulation. Science 1999, 286:2352-2355. 10.1126/science.286.5448.2352.
    • (1999) Science , vol.286 , pp. 2352-2355
    • Tan, J.1    Town, T.2    Paris, D.3    Mori, T.4    Suo, Z.5    Crawford, F.6
  • 108
    • 0032872925 scopus 로고    scopus 로고
    • Microglia induce myelin basic protein-specific T cell anergy or T cell activation, according to their state of activation
    • Matyszak M.K., Denis-Donini S., Citterio S., Longhi R., Granucci F., Ricciardi-Castagnoli P. Microglia induce myelin basic protein-specific T cell anergy or T cell activation, according to their state of activation. Eur. J. Immunol. 1999, 29:3063-3076. 10.1002/(SICI)1521-4141(199910)29:10<3063::AID-IMMU3063>3.0.CO;2-G.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 3063-3076
    • Matyszak, M.K.1    Denis-Donini, S.2    Citterio, S.3    Longhi, R.4    Granucci, F.5    Ricciardi-Castagnoli, P.6
  • 109
    • 0034749035 scopus 로고    scopus 로고
    • Expression of Fas ligand by microglia: possible role in glioma immune evasion
    • Badie B., Schartner J., Prabakaran S., Paul J., Vorpahl J. Expression of Fas ligand by microglia: possible role in glioma immune evasion. J. Neuroimmunol. 2001, 120:19-24.
    • (2001) J. Neuroimmunol. , vol.120 , pp. 19-24
    • Badie, B.1    Schartner, J.2    Prabakaran, S.3    Paul, J.4    Vorpahl, J.5
  • 110
    • 0037141153 scopus 로고    scopus 로고
    • Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles
    • Andreola G., Rivoltini L., Castelli C., Huber V., Perego P., Deho P., et al. Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. J. Exp. Med. 2002, 195:1303-1316.
    • (2002) J. Exp. Med. , vol.195 , pp. 1303-1316
    • Andreola, G.1    Rivoltini, L.2    Castelli, C.3    Huber, V.4    Perego, P.5    Deho, P.6
  • 111
    • 84879484111 scopus 로고    scopus 로고
    • Gliomas promote immunosuppression through induction of B7-H1 expression in tumor-associated macrophages
    • Bloch O., Crane C.A., Kaur R., Safaee M., Rutkowski M.J., Parsa A.T. Gliomas promote immunosuppression through induction of B7-H1 expression in tumor-associated macrophages. Clin. Cancer Res. 2013, 19:3165-3175. 10.1158/1078-0432.CCR-12-3314.
    • (2013) Clin. Cancer Res. , vol.19 , pp. 3165-3175
    • Bloch, O.1    Crane, C.A.2    Kaur, R.3    Safaee, M.4    Rutkowski, M.J.5    Parsa, A.T.6
  • 113
    • 33645543196 scopus 로고    scopus 로고
    • Induction of macrophagic prostaglandin E2 synthesis by glioma cells
    • Nakano Y., Kuroda E., Kito T., Yokota A., Yamashita U. Induction of macrophagic prostaglandin E2 synthesis by glioma cells. J. Neurosurg. 2006, 104:574-582. 10.3171/jns.2006.104.4.574.
    • (2006) J. Neurosurg. , vol.104 , pp. 574-582
    • Nakano, Y.1    Kuroda, E.2    Kito, T.3    Yokota, A.4    Yamashita, U.5
  • 114
    • 0025195323 scopus 로고
    • Influence of PGE2- and cAMP-modulating agents on human glioblastoma cell killing by interleukin-2-activated lymphocytes
    • Kuppner M.C., Sawamura Y., Hamou M.F., de Tribolet N. Influence of PGE2- and cAMP-modulating agents on human glioblastoma cell killing by interleukin-2-activated lymphocytes. J. Neurosurg. 1990, 72:619-625. 10.3171/jns.1990.72.4.0619.
    • (1990) J. Neurosurg. , vol.72 , pp. 619-625
    • Kuppner, M.C.1    Sawamura, Y.2    Hamou, M.F.3    de Tribolet, N.4
  • 115
    • 4644265937 scopus 로고    scopus 로고
    • Induction of a CD4+ T regulatory type 1 response by cyclooxygenase-2-overexpressing glioma
    • Akasaki Y., Liu G., Chung N.H.C., Ehtesham M., Black K.L., Yu J.S. Induction of a CD4+ T regulatory type 1 response by cyclooxygenase-2-overexpressing glioma. J. Immunol. 2004, 173:4352-4359.
    • (2004) J. Immunol. , vol.173 , pp. 4352-4359
    • Akasaki, Y.1    Liu, G.2    Chung, N.H.C.3    Ehtesham, M.4    Black, K.L.5    Yu, J.S.6
  • 116
    • 84888373474 scopus 로고    scopus 로고
    • Microglial activation milieu controls regulatory T cell responses
    • Ebner F., Brandt C., Thiele P., Richter D., Schliesser U., Siffrin V., et al. Microglial activation milieu controls regulatory T cell responses. J. Immunol. 2013, 191:5594-5602. 10.4049/jimmunol.1203331.
    • (2013) J. Immunol. , vol.191 , pp. 5594-5602
    • Ebner, F.1    Brandt, C.2    Thiele, P.3    Richter, D.4    Schliesser, U.5    Siffrin, V.6
  • 117
    • 49649093608 scopus 로고    scopus 로고
    • Human anti-inflammatory macrophages induce Foxp3+ GITR+CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1
    • Savage N.D.L., de Boer T., Walburg K.V., Joosten S.A., van Meijgaarden K., Geluk A., et al. Human anti-inflammatory macrophages induce Foxp3+ GITR+CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1. J. Immunol. 2008, 181:2220-2226.
    • (2008) J. Immunol. , vol.181 , pp. 2220-2226
    • Savage, N.D.L.1    de Boer, T.2    Walburg, K.V.3    Joosten, S.A.4    van Meijgaarden, K.5    Geluk, A.6
  • 118
    • 84889095438 scopus 로고    scopus 로고
    • Review: molecular mechanism of microglia stimulated glioblastoma invasion
    • Coniglio S.J., Segall J.E. Review: molecular mechanism of microglia stimulated glioblastoma invasion. Matrix Biol. 2013, 32:372-380. 10.1016/j.matbio.2013.07.008.
    • (2013) Matrix Biol. , vol.32 , pp. 372-380
    • Coniglio, S.J.1    Segall, J.E.2
  • 120
    • 84891873517 scopus 로고    scopus 로고
    • Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion
    • Vinnakota K., Hu F., Ku M.-C., Georgieva P.B., Szulzewsky F., Pohlmann A., et al. Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion. Neuro-Oncology 2013, 15:1457-1468. 10.1093/neuonc/not115.
    • (2013) Neuro-Oncology , vol.15 , pp. 1457-1468
    • Vinnakota, K.1    Hu, F.2    Ku, M.-C.3    Georgieva, P.B.4    Szulzewsky, F.5    Pohlmann, A.6
  • 121
    • 84884218376 scopus 로고    scopus 로고
    • The role of microglia and matrix metalloproteinases involvement in neuroinflammation and gliomas
    • Konnecke H., Bechmann I. The role of microglia and matrix metalloproteinases involvement in neuroinflammation and gliomas. Clin. Dev. Immunol. 2013, 2013. 10.1155/2013/914104.
    • (2013) Clin. Dev. Immunol. , vol.2013
    • Konnecke, H.1    Bechmann, I.2
  • 124
    • 84855188858 scopus 로고    scopus 로고
    • Microglial stress inducible protein 1 promotes proliferation and migration in human glioblastoma cells
    • da Fonseca A.C.C., Romão L., Amaral R.F., Assad Kahn S., Lobo D., Martins S., et al. Microglial stress inducible protein 1 promotes proliferation and migration in human glioblastoma cells. Neuroscience 2012, 200:130-141. 10.1016/j.neuroscience.2011.10.025.
    • (2012) Neuroscience , vol.200 , pp. 130-141
    • da Fonseca, A.C.C.1    Romão, L.2    Amaral, R.F.3    Assad Kahn, S.4    Lobo, D.5    Martins, S.6
  • 125
    • 84862879740 scopus 로고    scopus 로고
    • Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway
    • Ye X., Xu S., Xin Y., Yu S., Ping Y., Chen L., et al. Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway. J. Immunol. 2012, 189:444-453. 10.4049/jimmunol.1103248.
    • (2012) J. Immunol. , vol.189 , pp. 444-453
    • Ye, X.1    Xu, S.2    Xin, Y.3    Yu, S.4    Ping, Y.5    Chen, L.6
  • 126
    • 0029871064 scopus 로고    scopus 로고
    • Vascular endothelial growth factor production is stimulated by gangliosides and TGF-beta isoforms in human glioma cells in vitro
    • Koochekpour S., Merzak A., Pilkington G.J. Vascular endothelial growth factor production is stimulated by gangliosides and TGF-beta isoforms in human glioma cells in vitro. Cancer Lett. 1996, 102:209-215.
    • (1996) Cancer Lett. , vol.102 , pp. 209-215
    • Koochekpour, S.1    Merzak, A.2    Pilkington, G.J.3
  • 127
    • 84865614917 scopus 로고    scopus 로고
    • Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling
    • Coniglio S.J., Eugenin E., Dobrenis K., Stanley E.R., West B.L., Symons M.H., et al. Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling. Mol. Med. 2012, 18:519-527. 10.2119/molmed.2011.00217.
    • (2012) Mol. Med. , vol.18 , pp. 519-527
    • Coniglio, S.J.1    Eugenin, E.2    Dobrenis, K.3    Stanley, E.R.4    West, B.L.5    Symons, M.H.6
  • 128
    • 0033379594 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) and platelet-derived growth factor receptor-beta (PDGFR-beta) in human gliomas
    • Lafuente J.V., Adán B., Alkiza K., Garibi J.M., Rossi M., Cruz-Sánchez F.F. Expression of vascular endothelial growth factor (VEGF) and platelet-derived growth factor receptor-beta (PDGFR-beta) in human gliomas. J. Mol. Neurosci. 1999, 13:177-185. 10.1385/JMN:13:1-2:177.
    • (1999) J. Mol. Neurosci. , vol.13 , pp. 177-185
    • Lafuente, J.V.1    Adán, B.2    Alkiza, K.3    Garibi, J.M.4    Rossi, M.5    Cruz-Sánchez, F.F.6
  • 129
    • 64249115813 scopus 로고    scopus 로고
    • Induction of myeloid-derived suppressor cells by tumor exosomes
    • Xiang X., Poliakov A., Liu C., Liu Y., Deng Z., Wang J., et al. Induction of myeloid-derived suppressor cells by tumor exosomes. Int. J. Cancer 2009, 124:2621-2633. 10.1002/ijc.24249.
    • (2009) Int. J. Cancer , vol.124 , pp. 2621-2633
    • Xiang, X.1    Poliakov, A.2    Liu, C.3    Liu, Y.4    Deng, Z.5    Wang, J.6
  • 131
    • 84887149333 scopus 로고    scopus 로고
    • GM-CSF promotes the immunosuppressive activity of glioma-infiltrating myeloid cells through interleukin-4 receptor-α
    • Kohanbash G., McKaveney K., Sakaki M., Ueda R., Mintz A.H., Amankulor N., et al. GM-CSF promotes the immunosuppressive activity of glioma-infiltrating myeloid cells through interleukin-4 receptor-α. Cancer Res. 2013, 73:6413-6423. 10.1158/0008-5472.CAN-12-4124.
    • (2013) Cancer Res. , vol.73 , pp. 6413-6423
    • Kohanbash, G.1    McKaveney, K.2    Sakaki, M.3    Ueda, R.4    Mintz, A.H.5    Amankulor, N.6
  • 132
    • 31344474166 scopus 로고    scopus 로고
    • Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression
    • Serafini P., Borrello I., Bronte V. Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression. Semin. Cancer Biol. 2006, 16:53-65. 10.1016/j.semcancer.2005.07.005.
    • (2006) Semin. Cancer Biol. , vol.16 , pp. 53-65
    • Serafini, P.1    Borrello, I.2    Bronte, V.3
  • 133
    • 10244279184 scopus 로고    scopus 로고
    • Mechanisms and functional significance of tumour-induced dendritic-cell defects
    • Gabrilovich D. Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat. Rev. Immunol. 2004, 4:941-952. 10.1038/nri1498.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 941-952
    • Gabrilovich, D.1
  • 134
    • 77956920766 scopus 로고    scopus 로고
    • Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells
    • Lechner M.G., Liebertz D.J., Epstein A.L. Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells. J. Immunol. 2010, 185:2273-2284. 10.4049/jimmunol.1000901.
    • (2010) J. Immunol. , vol.185 , pp. 2273-2284
    • Lechner, M.G.1    Liebertz, D.J.2    Epstein, A.L.3
  • 136
    • 0032707364 scopus 로고    scopus 로고
    • Autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor in human gliomas with tumor progression
    • Mueller M.M., Herold-Mende C.C., Riede D., Lange M., Steiner H.H., Fusenig N.E. Autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor in human gliomas with tumor progression. Am. J. Pathol. 1999, 155:1557-1567. 10.1016/S0002-9440(10)65472-7.
    • (1999) Am. J. Pathol. , vol.155 , pp. 1557-1567
    • Mueller, M.M.1    Herold-Mende, C.C.2    Riede, D.3    Lange, M.4    Steiner, H.H.5    Fusenig, N.E.6
  • 137
    • 0031595633 scopus 로고    scopus 로고
    • Expression of interleukin-1beta mRNA and protein in human gliomas assessed by RT-PCR and immunohistochemistry
    • Sasaki A., Tamura M., Hasegawa M., Ishiuchi S., Hirato J., Nakazato Y. Expression of interleukin-1beta mRNA and protein in human gliomas assessed by RT-PCR and immunohistochemistry. J. Neuropathol. Exp. Neurol. 1998, 57:653-663.
    • (1998) J. Neuropathol. Exp. Neurol. , vol.57 , pp. 653-663
    • Sasaki, A.1    Tamura, M.2    Hasegawa, M.3    Ishiuchi, S.4    Hirato, J.5    Nakazato, Y.6
  • 138
    • 84863860246 scopus 로고    scopus 로고
    • Quantitative mRNA expression of genes involved in angiogenesis, coagulation and inflammation in multiforme glioblastoma tumoral tissue versus peritumoral brain tissue: lack of correlation with clinical data
    • Berindan-Neagoe I., Chiorean R., Braicu C., Florian I.S., Leucuta D., Crisan D., et al. Quantitative mRNA expression of genes involved in angiogenesis, coagulation and inflammation in multiforme glioblastoma tumoral tissue versus peritumoral brain tissue: lack of correlation with clinical data. Eur. Cytokine Netw. 2012, 23:45-55. 10.1684/ecn.2012.0302.
    • (2012) Eur. Cytokine Netw. , vol.23 , pp. 45-55
    • Berindan-Neagoe, I.1    Chiorean, R.2    Braicu, C.3    Florian, I.S.4    Leucuta, D.5    Crisan, D.6
  • 139
    • 84890126632 scopus 로고    scopus 로고
    • Glioma-derived galectin-1 regulates innate and adaptive antitumor immunity
    • Verschuere T., Toelen J., Maes W., Poirier F., Boon L., Tousseyn T., et al. Glioma-derived galectin-1 regulates innate and adaptive antitumor immunity. Int. J. Cancer 2014, 134:873-884. 10.1002/ijc.28426.
    • (2014) Int. J. Cancer , vol.134 , pp. 873-884
    • Verschuere, T.1    Toelen, J.2    Maes, W.3    Poirier, F.4    Boon, L.5    Tousseyn, T.6
  • 140
    • 50849139609 scopus 로고    scopus 로고
    • Glucocorticoids induce an activated, anti-inflammatory monocyte subset in mice that resembles myeloid-derived suppressor cells
    • Varga G., Ehrchen J., Tsianakas A., Tenbrock K., Rattenholl A., Seeliger S., et al. Glucocorticoids induce an activated, anti-inflammatory monocyte subset in mice that resembles myeloid-derived suppressor cells. J. Leukoc. Biol. 2008, 84:644-650. 10.1189/jlb.1107768.
    • (2008) J. Leukoc. Biol. , vol.84 , pp. 644-650
    • Varga, G.1    Ehrchen, J.2    Tsianakas, A.3    Tenbrock, K.4    Rattenholl, A.5    Seeliger, S.6
  • 141
    • 84882246825 scopus 로고    scopus 로고
    • Tumor-mediated inhibition of human dendritic cell differentiation and function is consistently counteracted by combined p38 MAPK and STAT3 inhibition
    • Oosterhoff D., Lougheed S., van de Ven R., Lindenberg J., van Cruijsen H., Hiddingh L., et al. Tumor-mediated inhibition of human dendritic cell differentiation and function is consistently counteracted by combined p38 MAPK and STAT3 inhibition. Oncoimmunology 2012, 1:649-658. 10.4161/onci.20365.
    • (2012) Oncoimmunology , vol.1 , pp. 649-658
    • Oosterhoff, D.1    Lougheed, S.2    van de Ven, R.3    Lindenberg, J.4    van Cruijsen, H.5    Hiddingh, L.6
  • 142
    • 80053046377 scopus 로고    scopus 로고
    • Glioblastoma-induced inhibition of Langerhans cell differentiation from CD34(+) precursors is mediated by IL-6 but unaffected by JAK2/STAT3 inhibition
    • van Cruijsen H., Oosterhoff D., Lindenberg J.J., Lougheed S.M., Fehres C., Weijers K., et al. Glioblastoma-induced inhibition of Langerhans cell differentiation from CD34(+) precursors is mediated by IL-6 but unaffected by JAK2/STAT3 inhibition. Immunotherapy 2011, 3:1051-1061. 10.2217/imt.11.107.
    • (2011) Immunotherapy , vol.3 , pp. 1051-1061
    • van Cruijsen, H.1    Oosterhoff, D.2    Lindenberg, J.J.3    Lougheed, S.M.4    Fehres, C.5    Weijers, K.6
  • 143
  • 144
    • 80051627660 scopus 로고    scopus 로고
    • M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4+ Th1 cells
    • Heusinkveld M., de Vos P.J., van Steenwijk R., Goedemans T.H., Ramwadhdoebe A., Gorter M.J.P.Welters, et al. M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4+ Th1 cells. J. Immunol. 2011, 187:1157-1165. 10.4049/jimmunol.1100889.
    • (2011) J. Immunol. , vol.187 , pp. 1157-1165
    • Heusinkveld, M.1    de Vos, P.J.2    van Steenwijk, R.3    Goedemans, T.H.4    Ramwadhdoebe, A.5    Gorter, M.J.P.W.6
  • 145
    • 81555228400 scopus 로고    scopus 로고
    • Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells
    • Obermajer N., Muthuswamy R., Lesnock J., Edwards R.P., Kalinski P. Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells. Blood 2011, 118:5498-5505. 10.1182/blood-2011-07-365825.
    • (2011) Blood , vol.118 , pp. 5498-5505
    • Obermajer, N.1    Muthuswamy, R.2    Lesnock, J.3    Edwards, R.P.4    Kalinski, P.5
  • 146
    • 84921908421 scopus 로고    scopus 로고
    • Cox2 blockade suppresses gliomagenesis by inhibiting CCL2-mediated accumulation of myeloid-derived suppressor cells in glioma sites
    • Fujita M., Kohanbash G., McDonald H.A., Delamarre L., Decker S.A., Ohlfest J.R., et al. Cox2 blockade suppresses gliomagenesis by inhibiting CCL2-mediated accumulation of myeloid-derived suppressor cells in glioma sites. Neuro-Oncology 2010, 12:iv32-iv36. 10.1093/neuonc/noq116.s5.
    • (2010) Neuro-Oncology , vol.12 , pp. iv32-iv36
    • Fujita, M.1    Kohanbash, G.2    McDonald, H.A.3    Delamarre, L.4    Decker, S.A.5    Ohlfest, J.R.6
  • 147
    • 79953324535 scopus 로고    scopus 로고
    • COX-2 blockade suppresses gliomagenesis by inhibiting myeloid-derived suppressor cells
    • Fujita M., Kohanbash G., Fellows-Mayle W., Hamilton R.L., Komohara Y., Decker S.A., et al. COX-2 blockade suppresses gliomagenesis by inhibiting myeloid-derived suppressor cells. Cancer Res. 2011, 71:2664-2674. 10.1158/0008-5472.CAN-10-3055.
    • (2011) Cancer Res. , vol.71 , pp. 2664-2674
    • Fujita, M.1    Kohanbash, G.2    Fellows-Mayle, W.3    Hamilton, R.L.4    Komohara, Y.5    Decker, S.A.6
  • 148
    • 77953541622 scopus 로고    scopus 로고
    • Tumor-infiltrating, myeloid-derived suppressor cells inhibit T cell activity by nitric oxide production in an intracranial rat glioma+vaccination model
    • Jia W., Jackson-Cook C., Graf M.R. Tumor-infiltrating, myeloid-derived suppressor cells inhibit T cell activity by nitric oxide production in an intracranial rat glioma+vaccination model. J. Neuroimmunol. 2010, 223:20-30. 10.1016/j.jneuroim.2010.03.011.
    • (2010) J. Neuroimmunol. , vol.223 , pp. 20-30
    • Jia, W.1    Jackson-Cook, C.2    Graf, M.R.3
  • 149
    • 42349094504 scopus 로고    scopus 로고
    • Tumor escape mechanism governed by myeloid-derived suppressor cells
    • Nagaraj S., Gabrilovich D.I. Tumor escape mechanism governed by myeloid-derived suppressor cells. Cancer Res. 2008, 68:2561-2563. 10.1158/0008-5472.CAN-07-6229.
    • (2008) Cancer Res. , vol.68 , pp. 2561-2563
    • Nagaraj, S.1    Gabrilovich, D.I.2
  • 150
    • 41149148269 scopus 로고    scopus 로고
    • Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives
    • Rodriguez P.C., Ochoa A.C. Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives. Immunol. Rev. 2008, 222:180-191. 10.1111/j.1600-065X.2008.00608.x.
    • (2008) Immunol. Rev. , vol.222 , pp. 180-191
    • Rodriguez, P.C.1    Ochoa, A.C.2
  • 151
    • 81255129169 scopus 로고    scopus 로고
    • Neutrophil degranulation and immunosuppression in patients with GBM: Restoration of cellular immune function by targeting arginase I
    • Sippel T.R., White J., Nag K., Tsvankin V., Klaassen M., Kleinschmidt-DeMasters B.K., et al. Neutrophil degranulation and immunosuppression in patients with GBM: Restoration of cellular immune function by targeting arginase I. Clin. Cancer Res. 2011, 17:6992-7002. 10.1158/1078-0432.CCR-11-1107.
    • (2011) Clin. Cancer Res. , vol.17 , pp. 6992-7002
    • Sippel, T.R.1    White, J.2    Nag, K.3    Tsvankin, V.4    Klaassen, M.5    Kleinschmidt-DeMasters, B.K.6
  • 154
    • 79957959848 scopus 로고    scopus 로고
    • Using an ancient tool for igniting and propagating immune tolerance: IDO as an inducer and amplifier of regulatory T cell functions
    • Fallarino F., Grohmann U. Using an ancient tool for igniting and propagating immune tolerance: IDO as an inducer and amplifier of regulatory T cell functions. Curr. Med. Chem. 2011, 18:2215-2221.
    • (2011) Curr. Med. Chem. , vol.18 , pp. 2215-2221
    • Fallarino, F.1    Grohmann, U.2
  • 155
    • 31544446571 scopus 로고    scopus 로고
    • Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • Huang B., Pan P.-Y., Li Q., Sato A.I., Levy D.E., Bromberg J., et al. Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res. 2006, 66:1123-1131. 10.1158/0008-5472.CAN-05-1299.
    • (2006) Cancer Res. , vol.66 , pp. 1123-1131
    • Huang, B.1    Pan, P.-Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6
  • 156
    • 48549085973 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells
    • Serafini P., Mgebroff S., Noonan K., Borrello I. Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res. 2008, 68:5439-5449. 10.1158/0008-5472.CAN-07-6621.
    • (2008) Cancer Res. , vol.68 , pp. 5439-5449
    • Serafini, P.1    Mgebroff, S.2    Noonan, K.3    Borrello, I.4
  • 157
    • 84864598740 scopus 로고    scopus 로고
    • Treg infiltration in glioma: a hurdle for antiglioma immunotherapy
    • Vandenberk L., Van Gool S.W. Treg infiltration in glioma: a hurdle for antiglioma immunotherapy. Immunotherapy 2012, 4:675-678. 10.2217/imt.12.64.
    • (2012) Immunotherapy , vol.4 , pp. 675-678
    • Vandenberk, L.1    Van Gool, S.W.2
  • 158
    • 37349100945 scopus 로고    scopus 로고
    • Abrogation of TGFβ signaling in mammary carcinomas recruits Gr-1+CD11b+myeloid cells that promote metastasis
    • Yang L., Huang J., Ren X., Gorska A.E., Chytil A., Aakre M., et al. Abrogation of TGFβ signaling in mammary carcinomas recruits Gr-1+CD11b+myeloid cells that promote metastasis. Cancer Cell 2008, 13:23-35. 10.1016/j.ccr.2007.12.004.
    • (2008) Cancer Cell , vol.13 , pp. 23-35
    • Yang, L.1    Huang, J.2    Ren, X.3    Gorska, A.E.4    Chytil, A.5    Aakre, M.6
  • 159
  • 160
    • 79959271214 scopus 로고    scopus 로고
    • Plasticity of human Th17 cells and iTregs is orchestrated by different subsets of myeloid cells
    • Hoechst B., Gamrekelashvili J., Manns M.P., Greten T.F., Korangy F. Plasticity of human Th17 cells and iTregs is orchestrated by different subsets of myeloid cells. Blood 2011, 117:6532-6541. 10.1182/blood-2010-11-317321.
    • (2011) Blood , vol.117 , pp. 6532-6541
    • Hoechst, B.1    Gamrekelashvili, J.2    Manns, M.P.3    Greten, T.F.4    Korangy, F.5
  • 161
    • 84868035933 scopus 로고    scopus 로고
    • Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype
    • Piao Y., Liang J., Holmes L., Zurita A.J., Henry V., Heymach J.V., et al. Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype. Neuro-Oncology 2012, 14:1379-1392. 10.1093/neuonc/nos158.
    • (2012) Neuro-Oncology , vol.14 , pp. 1379-1392
    • Piao, Y.1    Liang, J.2    Holmes, L.3    Zurita, A.J.4    Henry, V.5    Heymach, J.V.6
  • 162
    • 84921912069 scopus 로고    scopus 로고
    • Using REMBRANDT to paint in the details of glioma biology: Applications for future immunotherapy
    • (accessed January 28, 2014)), T. Lichtor (Ed, InTech, A.Q., N.T.
    • A.Q., N.T., Ge L., Arismendi G., Paleo B., E.J., et al. Using REMBRANDT to paint in the details of glioma biology: Applications for future immunotherapy. Evol. Mol. Biol. Brain Tumors Ther. Implic 2013, InTech, (http://www.intechopen.com/books/howtoreference/evolution-of-the-molecular-biology-of-brain-tumors-and-the-therapeutic-implications/using-rembrandt-to-paint-in-the-details-of-glioma-biology-applications-for-future-immunotherapy (accessed January 28, 2014)). T. Lichtor (Ed.).
    • (2013) Evol. Mol. Biol. Brain Tumors Ther. Implic
    • Ge, L.1    Arismendi, G.2    Paleo, B.E.J.3
  • 163
    • 46949094641 scopus 로고    scopus 로고
    • Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics
    • Umemura N., Saio M., Suwa T., Kitoh Y., Bai J., Nonaka K., et al. Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics. J. Leukoc. Biol. 2008, 83:1136-1144. 10.1189/jlb.0907611.
    • (2008) J. Leukoc. Biol. , vol.83 , pp. 1136-1144
    • Umemura, N.1    Saio, M.2    Suwa, T.3    Kitoh, Y.4    Bai, J.5    Nonaka, K.6
  • 164
    • 84893381289 scopus 로고    scopus 로고
    • Transmembrane TNF-α promotes suppressive activities of myeloid-derived suppressor cells via TNFR2
    • Hu X., Li B., Li X., Zhao X., Wan L., Lin G., et al. Transmembrane TNF-α promotes suppressive activities of myeloid-derived suppressor cells via TNFR2. J. Immunol. 2014, 192:1320-1331. 10.4049/jimmunol.1203195.
    • (2014) J. Immunol. , vol.192 , pp. 1320-1331
    • Hu, X.1    Li, B.2    Li, X.3    Zhao, X.4    Wan, L.5    Lin, G.6
  • 165
    • 77955060375 scopus 로고    scopus 로고
    • Contribution of myeloid-derived suppressor cells to tumor-induced immune suppression, angiogenesis, invasion and metastasis
    • Ye X.-Z., Yu S.-C., Bian X.-W. Contribution of myeloid-derived suppressor cells to tumor-induced immune suppression, angiogenesis, invasion and metastasis. J. Genet. Genomics 2010, 37:423-430. 10.1016/S1673-8527(09)60061-8.
    • (2010) J. Genet. Genomics , vol.37 , pp. 423-430
    • Ye, X.-Z.1    Yu, S.-C.2    Bian, X.-W.3
  • 166
    • 84907424318 scopus 로고    scopus 로고
    • Cancer secretomes and their place in supplementing other hallmarks of cancer
    • Patel S., Wetie A.G.N., Darie C.C., Clarkson B.D. Cancer secretomes and their place in supplementing other hallmarks of cancer. Adv. Exp. Med. Biol. 2014, 806:409-442. 10.1007/978-3-319-06068-2_20.
    • (2014) Adv. Exp. Med. Biol. , vol.806 , pp. 409-442
    • Patel, S.1    Wetie, A.G.N.2    Darie, C.C.3    Clarkson, B.D.4
  • 167
    • 57049103401 scopus 로고    scopus 로고
    • Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
    • Skog J., Würdinger T., van Rijn S., Meijer D.H., Gainche L., Sena-Esteves M., et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat. Cell Biol. 2008, 10:1470-1476. 10.1038/ncb1800.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1470-1476
    • Skog, J.1    Würdinger, T.2    van Rijn, S.3    Meijer, D.H.4    Gainche, L.5    Sena-Esteves, M.6
  • 168
    • 84867120348 scopus 로고    scopus 로고
    • Rab27a supports exosome-dependent and -independent mechanisms that modify the tumor microenvironment and can promote tumor progression
    • Bobrie A., Krumeich S., Reyal F., Recchi C., Moita L.F., Seabra M.C., et al. Rab27a supports exosome-dependent and -independent mechanisms that modify the tumor microenvironment and can promote tumor progression. Cancer Res. 2012, 72:4920-4930. 10.1158/0008-5472.CAN-12-0925.
    • (2012) Cancer Res. , vol.72 , pp. 4920-4930
    • Bobrie, A.1    Krumeich, S.2    Reyal, F.3    Recchi, C.4    Moita, L.F.5    Seabra, M.C.6
  • 169
    • 83455172635 scopus 로고    scopus 로고
    • Tumor cell cross talk with tumor-associated leukocytes leads to induction of tumor exosomal fibronectin and promotes tumor progression
    • Deng Z., Cheng Z., Xiang X., Yan J., Zhuang X., Liu C., et al. Tumor cell cross talk with tumor-associated leukocytes leads to induction of tumor exosomal fibronectin and promotes tumor progression. Am. J. Pathol. 2012, 180:390-398. 10.1016/j.ajpath.2011.09.023.
    • (2012) Am. J. Pathol. , vol.180 , pp. 390-398
    • Deng, Z.1    Cheng, Z.2    Xiang, X.3    Yan, J.4    Zhuang, X.5    Liu, C.6
  • 170
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi H., Ekström K., Bossios A., Sjöstrand M., Lee J.J., Lötvall J.O. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol. 2007, 9:654-659. 10.1038/ncb1596.
    • (2007) Nat. Cell Biol. , vol.9 , pp. 654-659
    • Valadi, H.1    Ekström, K.2    Bossios, A.3    Sjöstrand, M.4    Lee, J.J.5    Lötvall, J.O.6
  • 171
    • 84919845773 scopus 로고    scopus 로고
    • Extracellular vesicles shed by glioma cells: pathogenic role and clinical value
    • Chistiakov D.A., Chekhonin V.P. Extracellular vesicles shed by glioma cells: pathogenic role and clinical value. Tumor Biol. 2014, 1-14. 10.1007/s13277-014-2262-9.
    • (2014) Tumor Biol. , pp. 1-14
    • Chistiakov, D.A.1    Chekhonin, V.P.2
  • 172
    • 84918774361 scopus 로고    scopus 로고
    • Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells
    • Kore R.A., Abraham E.C. Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. Biochem. Biophys. Res. Commun. 2014, 10.1016/j.bbrc.2014.09.068.
    • (2014) Biochem. Biophys. Res. Commun.
    • Kore, R.A.1    Abraham, E.C.2
  • 175
    • 84886387008 scopus 로고    scopus 로고
    • Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity
    • Christianson H.C., Svensson K.J., van Kuppevelt T.H., Li J.-P., Belting M. Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:17380-17385. 10.1073/pnas.1304266110.
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , pp. 17380-17385
    • Christianson, H.C.1    Svensson, K.J.2    van Kuppevelt, T.H.3    Li, J.-P.4    Belting, M.5
  • 176
    • 84879046970 scopus 로고    scopus 로고
    • Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1
    • Svensson K.J., Christianson H.C., Wittrup A., Bourseau-Guilmain E., Lindqvist E., Svensson L.M., et al. Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1. J. Biol. Chem. 2013, 288:17713-17724. 10.1074/jbc.M112.445403.
    • (2013) J. Biol. Chem. , vol.288 , pp. 17713-17724
    • Svensson, K.J.1    Christianson, H.C.2    Wittrup, A.3    Bourseau-Guilmain, E.4    Lindqvist, E.5    Svensson, L.M.6
  • 177
    • 84876927914 scopus 로고    scopus 로고
    • Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
    • Kucharzewska P., Christianson H.C., Welch J.E., Svensson K.J., Fredlund E., Ringner M., et al. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:7312-7317. 10.1073/pnas.1220998110.
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , pp. 7312-7317
    • Kucharzewska, P.1    Christianson, H.C.2    Welch, J.E.3    Svensson, K.J.4    Fredlund, E.5    Ringner, M.6
  • 178
    • 84878654194 scopus 로고    scopus 로고
    • Extracellular vesicles as prospective carriers of oncogenic protein signatures in adult and paediatric brain tumours
    • Garnier D., Jabado N., Rak J. Extracellular vesicles as prospective carriers of oncogenic protein signatures in adult and paediatric brain tumours. Proteomics 2013, 13:1595-1607. 10.1002/pmic.201200360.
    • (2013) Proteomics , vol.13 , pp. 1595-1607
    • Garnier, D.1    Jabado, N.2    Rak, J.3
  • 179
    • 84862908547 scopus 로고    scopus 로고
    • Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes
    • Montecalvo A., Larregina A.T., Shufesky W.J., Stolz D.B., Sullivan M.L.G., Karlsson J.M., et al. Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Blood 2012, 119:756-766. 10.1182/blood-2011-02-338004.
    • (2012) Blood , vol.119 , pp. 756-766
    • Montecalvo, A.1    Larregina, A.T.2    Shufesky, W.J.3    Stolz, D.B.4    Sullivan, M.L.G.5    Karlsson, J.M.6
  • 180
    • 71749102668 scopus 로고    scopus 로고
    • Microenvironmental pH is a key factor for exosome traffic in tumor cells
    • Parolini I., Federici C., Raggi C., Lugini L., Palleschi S., De Milito A., et al. Microenvironmental pH is a key factor for exosome traffic in tumor cells. J. Biol. Chem. 2009, 284:34211-34222. 10.1074/jbc.M109.041152.
    • (2009) J. Biol. Chem. , vol.284 , pp. 34211-34222
    • Parolini, I.1    Federici, C.2    Raggi, C.3    Lugini, L.4    Palleschi, S.5    De Milito, A.6
  • 181
    • 77957269172 scopus 로고    scopus 로고
    • Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy
    • Tian T., Wang Y., Wang H., Zhu Z., Xiao Z. Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy. J. Cell. Biochem. 2010, 111:488-496. 10.1002/jcb.22733.
    • (2010) J. Cell. Biochem. , vol.111 , pp. 488-496
    • Tian, T.1    Wang, Y.2    Wang, H.3    Zhu, Z.4    Xiao, Z.5
  • 183
  • 185
    • 77958086765 scopus 로고    scopus 로고
    • Exosomal membrane molecules are potent immune response modulators
    • Anand P.K. Exosomal membrane molecules are potent immune response modulators. Commun. Integr. Biol. 2010, 3:405-408. 10.4161/cib.3.5.12474.
    • (2010) Commun. Integr. Biol. , vol.3 , pp. 405-408
    • Anand, P.K.1
  • 187
    • 84866378995 scopus 로고    scopus 로고
    • Glioblastoma-derived exosomes contribute to tumor immune evasion
    • Sabin K.Z., Lebert D., Thibado V., Rovin R., Lawrence J., Winn R. Glioblastoma-derived exosomes contribute to tumor immune evasion. Neuro-Oncology 2011, 13:iii30-iii33. 10.1093/neuonc/nor150.
    • (2011) Neuro-Oncology , vol.13 , pp. 330-333
    • Sabin, K.Z.1    Lebert, D.2    Thibado, V.3    Rovin, R.4    Lawrence, J.5    Winn, R.6
  • 188
    • 76649097628 scopus 로고    scopus 로고
    • Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells
    • Chalmin F., Ladoire S., Mignot G., Vincent J., Bruchard M., Remy-Martin J.-P., et al. Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. J. Clin. Invest. 2010, 120:457-471. 10.1172/JCI40483.
    • (2010) J. Clin. Invest. , vol.120 , pp. 457-471
    • Chalmin, F.1    Ladoire, S.2    Mignot, G.3    Vincent, J.4    Bruchard, M.5    Remy-Martin, J.-P.6
  • 191
    • 80053175966 scopus 로고    scopus 로고
    • Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells
    • Yang M., Chen J., Su F., Yu B., Su F., Lin L., et al. Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells. Mol. Cancer 2011, 10:117. 10.1186/1476-4598-10-117.
    • (2011) Mol. Cancer , vol.10 , pp. 117
    • Yang, M.1    Chen, J.2    Su, F.3    Yu, B.4    Su, F.5    Lin, L.6
  • 192
    • 84902345206 scopus 로고    scopus 로고
    • MiRNA-mediated immune regulation and immunotherapeutic potential in glioblastoma
    • Jethwa K., Wei J., McEnery K., Heimberger A.B. miRNA-mediated immune regulation and immunotherapeutic potential in glioblastoma. Clin. Invest. 2011, 1:1637-1650. 10.4155/cli.11.159.
    • (2011) Clin. Invest. , vol.1 , pp. 1637-1650
    • Jethwa, K.1    Wei, J.2    McEnery, K.3    Heimberger, A.B.4
  • 194
    • 84878463836 scopus 로고    scopus 로고
    • Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth
    • Katakowski M., Buller B., Zheng X., Lu Y., Rogers T., Osobamiro O., et al. Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth. Cancer Lett. 2013, 335:201-204. 10.1016/j.canlet.2013.02.019.
    • (2013) Cancer Lett. , vol.335 , pp. 201-204
    • Katakowski, M.1    Buller, B.2    Zheng, X.3    Lu, Y.4    Rogers, T.5    Osobamiro, O.6
  • 195
    • 84893851347 scopus 로고    scopus 로고
    • Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1
    • Bronisz A., Wang Y., Nowicki M.O., Peruzzi P., Ansari K.I., Ogawa D., et al. Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. Cancer Res. 2014, 74:738-750. 10.1158/0008-5472.CAN-13-2650.
    • (2014) Cancer Res. , vol.74 , pp. 738-750
    • Bronisz, A.1    Wang, Y.2    Nowicki, M.O.3    Peruzzi, P.4    Ansari, K.I.5    Ogawa, D.6
  • 197
    • 84907415649 scopus 로고    scopus 로고
    • Nontemplated nucleotide additions distinguish the small RNA composition in cells from exosomes
    • Koppers-Lalic D., Hackenberg M., Bijnsdorp I.V., van Eijndhoven M.A.J., Sadek P., Sie D., et al. Nontemplated nucleotide additions distinguish the small RNA composition in cells from exosomes. Cell Rep. 2014, 8:1649-1658. 10.1016/j.celrep.2014.08.027.
    • (2014) Cell Rep. , vol.8 , pp. 1649-1658
    • Koppers-Lalic, D.1    Hackenberg, M.2    Bijnsdorp, I.V.3    van Eijndhoven, M.A.J.4    Sadek, P.5    Sie, D.6
  • 198
    • 84883111834 scopus 로고    scopus 로고
    • Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells
    • Li C.C., Eaton S.A., Young P.E., Lee M., Shuttleworth R., Humphreys D.T., et al. Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells. RNA Biol. 2013, 10:1333-1344. 10.4161/rna.25281.
    • (2013) RNA Biol. , vol.10 , pp. 1333-1344
    • Li, C.C.1    Eaton, S.A.2    Young, P.E.3    Lee, M.4    Shuttleworth, R.5    Humphreys, D.T.6
  • 199
    • 79952070774 scopus 로고    scopus 로고
    • The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts
    • Peinado H., Lavotshkin S., Lyden D. The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts. Semin. Cancer Biol. 2011, 21:139-146. 10.1016/j.semcancer.2011.01.002.
    • (2011) Semin. Cancer Biol. , vol.21 , pp. 139-146
    • Peinado, H.1    Lavotshkin, S.2    Lyden, D.3
  • 200
    • 84862007577 scopus 로고    scopus 로고
    • Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
    • Peinado H., Alečković M., Lavotshkin S., Matei I., Costa-Silva B., Moreno-Bueno G., et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat. Med. 2012, 18:883-891. 10.1038/nm.2753.
    • (2012) Nat. Med. , vol.18 , pp. 883-891
    • Peinado, H.1    Alečković, M.2    Lavotshkin, S.3    Matei, I.4    Costa-Silva, B.5    Moreno-Bueno, G.6
  • 201
    • 84881112672 scopus 로고    scopus 로고
    • The evolution of the cancer niche during multistage carcinogenesis
    • Barcellos-Hoff M.H., Lyden D., Wang T.C. The evolution of the cancer niche during multistage carcinogenesis. Nat. Rev. Cancer 2013, 13:511-518. 10.1038/nrc3536.
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 511-518
    • Barcellos-Hoff, M.H.1    Lyden, D.2    Wang, T.C.3
  • 202
    • 77049115799 scopus 로고    scopus 로고
    • Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription
    • Aliotta J.M., Pereira M., Johnson K.W., de Paz N., Dooner M.S., Puente N., et al. Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription. Exp. Hematol. 2010, 38:233-245. 10.1016/j.exphem.2010.01.002.
    • (2010) Exp. Hematol. , vol.38 , pp. 233-245
    • Aliotta, J.M.1    Pereira, M.2    Johnson, K.W.3    de Paz, N.4    Dooner, M.S.5    Puente, N.6
  • 203
    • 34748870750 scopus 로고    scopus 로고
    • Alteration of marrow cell gene expression, protein production, and engraftment into lung by lung-derived microvesicles: a novel mechanism for phenotype modulation
    • Aliotta J.M., Sanchez-Guijo F.M., Dooner G.J., Johnson K.W., Dooner M.S., Greer K.A., et al. Alteration of marrow cell gene expression, protein production, and engraftment into lung by lung-derived microvesicles: a novel mechanism for phenotype modulation. Stem Cells 2007, 25:2245-2256. 10.1634/stemcells. 2007-0128.
    • (2007) Stem Cells , vol.25 , pp. 2245-2256
    • Aliotta, J.M.1    Sanchez-Guijo, F.M.2    Dooner, G.J.3    Johnson, K.W.4    Dooner, M.S.5    Greer, K.A.6
  • 205
    • 0021280828 scopus 로고
    • Tissue factor in microvesicles shed from U87MG human glioblastoma cells induces coagulation, platelet aggregation, and thrombogenesis
    • Bastida E., Ordinas A., Escolar G., Jamieson G.A. Tissue factor in microvesicles shed from U87MG human glioblastoma cells induces coagulation, platelet aggregation, and thrombogenesis. Blood 1984, 64:177-184.
    • (1984) Blood , vol.64 , pp. 177-184
    • Bastida, E.1    Ordinas, A.2    Escolar, G.3    Jamieson, G.A.4
  • 206
    • 81255205399 scopus 로고    scopus 로고
    • Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis
    • Labelle M., Begum S., Hynes R.O. Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis. Cancer Cell 2011, 20:576-590. 10.1016/j.ccr.2011.09.009.
    • (2011) Cancer Cell , vol.20 , pp. 576-590
    • Labelle, M.1    Begum, S.2    Hynes, R.O.3
  • 207
    • 33751513059 scopus 로고    scopus 로고
    • Platelet-derived microvesicles induce differential gene expression in monocytic cells: a DNA microarray study
    • Setzer F., Oberle V., Bläss M., Möller E., Russwurm S., Deigner H.-P., et al. Platelet-derived microvesicles induce differential gene expression in monocytic cells: a DNA microarray study. Platelets 2006, 17:571-576. 10.1080/09537100600760244.
    • (2006) Platelets , vol.17 , pp. 571-576
    • Setzer, F.1    Oberle, V.2    Bläss, M.3    Möller, E.4    Russwurm, S.5    Deigner, H.-P.6
  • 208
    • 79251478398 scopus 로고    scopus 로고
    • Contribution of platelets to tumour metastasis
    • Gay L.J., Felding-Habermann B. Contribution of platelets to tumour metastasis. Nat. Rev. Cancer 2011, 11:123-134. 10.1038/nrc3004.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 123-134
    • Gay, L.J.1    Felding-Habermann, B.2
  • 209
    • 84857022406 scopus 로고    scopus 로고
    • Platelet-derived microvesicles: multitalented participants in intercellular communication
    • Aatonen M., Grönholm M., Siljander P.R.-M. Platelet-derived microvesicles: multitalented participants in intercellular communication. Semin. Thromb. Hemost. 2012, 38:102-113. 10.1055/s-0031-1300956.
    • (2012) Semin. Thromb. Hemost. , vol.38 , pp. 102-113
    • Aatonen, M.1    Grönholm, M.2    Siljander, P.R.-M.3
  • 210
    • 77953951477 scopus 로고    scopus 로고
    • Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis
    • Zaslavsky A., Baek K.-H., Lynch R.C., Short S., Grillo J., Folkman J., et al. Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis. Blood 2010, 115:4605-4613. 10.1182/blood-2009-09-242065.
    • (2010) Blood , vol.115 , pp. 4605-4613
    • Zaslavsky, A.1    Baek, K.-H.2    Lynch, R.C.3    Short, S.4    Grillo, J.5    Folkman, J.6
  • 211
    • 79953825324 scopus 로고    scopus 로고
    • A novel role for platelet secretion in angiogenesis: mediating bone marrow-derived cell mobilization and homing
    • Feng W., Madajka M., Kerr B.A., Mahabeleshwar G.H., Whiteheart S.W., Byzova T.V. A novel role for platelet secretion in angiogenesis: mediating bone marrow-derived cell mobilization and homing. Blood 2011, 117:3893-3902. 10.1182/blood-2010-08-304808.
    • (2011) Blood , vol.117 , pp. 3893-3902
    • Feng, W.1    Madajka, M.2    Kerr, B.A.3    Mahabeleshwar, G.H.4    Whiteheart, S.W.5    Byzova, T.V.6
  • 212
    • 33947221678 scopus 로고    scopus 로고
    • Platelets and stromal cell-derived factor-1 in progenitor cell recruitment
    • Stellos K., Gawaz M. Platelets and stromal cell-derived factor-1 in progenitor cell recruitment. Semin. Thromb. Hemost. 2007, 33:159-164. 10.1055/s-2007-969029.
    • (2007) Semin. Thromb. Hemost. , vol.33 , pp. 159-164
    • Stellos, K.1    Gawaz, M.2
  • 213
    • 84871480929 scopus 로고    scopus 로고
    • Identification of luminal breast cancers that establish a tumor-supportive macroenvironment defined by proangiogenic platelets and bone marrow-derived cells
    • Kuznetsov H.S., Marsh T., Markens B.A., Castaño Z., Greene-Colozzi A., Hay S.A., et al. Identification of luminal breast cancers that establish a tumor-supportive macroenvironment defined by proangiogenic platelets and bone marrow-derived cells. Cancer Discov. 2012, 2:1150-1165. 10.1158/2159-8290.CD-12-0216.
    • (2012) Cancer Discov. , vol.2 , pp. 1150-1165
    • Kuznetsov, H.S.1    Marsh, T.2    Markens, B.A.3    Castaño, Z.4    Greene-Colozzi, A.5    Hay, S.A.6
  • 215
    • 84872598543 scopus 로고    scopus 로고
    • Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with α5β1 integrin in glioma
    • Kesanakurti D., Chetty C., Dinh D.H., Gujrati M., Rao J.S. Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with α5β1 integrin in glioma. Oncogene 2013, 32:327-340. 10.1038/onc.2012.52.
    • (2013) Oncogene , vol.32 , pp. 327-340
    • Kesanakurti, D.1    Chetty, C.2    Dinh, D.H.3    Gujrati, M.4    Rao, J.S.5
  • 217
    • 1842292742 scopus 로고    scopus 로고
    • Serotonin acts as a radical scavenger and is oxidized to a dimer during the respiratory burst of activated microglia
    • Huether G., Fettkötter I., Keilhoff G., Wolf G. Serotonin acts as a radical scavenger and is oxidized to a dimer during the respiratory burst of activated microglia. J. Neurochem. 1997, 69:2096-2101.
    • (1997) J. Neurochem. , vol.69 , pp. 2096-2101
    • Huether, G.1    Fettkötter, I.2    Keilhoff, G.3    Wolf, G.4
  • 218
    • 33646348133 scopus 로고    scopus 로고
    • The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines
    • Rhodes K.E., Raivich G., Fawcett J.W. The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines. Neuroscience 2006, 140:87-100. 10.1016/j.neuroscience.2006.01.055.
    • (2006) Neuroscience , vol.140 , pp. 87-100
    • Rhodes, K.E.1    Raivich, G.2    Fawcett, J.W.3
  • 219
    • 82955193777 scopus 로고    scopus 로고
    • Differential effects of tumor-platelet interaction in vitro and in vivo in glioblastoma
    • Brockmann M.A., Bender B., Plaxina E., Nolte I., Erber R., Lamszus K., et al. Differential effects of tumor-platelet interaction in vitro and in vivo in glioblastoma. J. Neurooncol. 2011, 105:45-56. 10.1007/s11060-011-0560-2.
    • (2011) J. Neurooncol. , vol.105 , pp. 45-56
    • Brockmann, M.A.1    Bender, B.2    Plaxina, E.3    Nolte, I.4    Erber, R.5    Lamszus, K.6
  • 220
    • 34547443073 scopus 로고    scopus 로고
    • Preoperative thrombocytosis predicts poor survival in patients with glioblastoma
    • Brockmann M.A., Giese A., Mueller K., Kaba F.J., Lohr F., Weiss C., et al. Preoperative thrombocytosis predicts poor survival in patients with glioblastoma. Neuro-Oncology 2007, 9:335-342. 10.1215/15228517-2007-013.
    • (2007) Neuro-Oncology , vol.9 , pp. 335-342
    • Brockmann, M.A.1    Giese, A.2    Mueller, K.3    Kaba, F.J.4    Lohr, F.5    Weiss, C.6
  • 221
    • 84866734421 scopus 로고    scopus 로고
    • Change in platelet levels during radiotherapy with concurrent and adjuvant temozolomide for the treatment of glioblastoma: a novel prognostic factor for survival
    • Williams M., Liu Z.W., Woolf D., Hargreaves S., Michalarea V., Menashy R., et al. Change in platelet levels during radiotherapy with concurrent and adjuvant temozolomide for the treatment of glioblastoma: a novel prognostic factor for survival. J. Cancer Res. Clin. Oncol. 2012, 138:1683-1688. 10.1007/s00432-012-1243-x.
    • (2012) J. Cancer Res. Clin. Oncol. , vol.138 , pp. 1683-1688
    • Williams, M.1    Liu, Z.W.2    Woolf, D.3    Hargreaves, S.4    Michalarea, V.5    Menashy, R.6
  • 222
    • 62749198722 scopus 로고    scopus 로고
    • Dynamics of central and peripheral immunomodulation in a murine glioma model
    • Kennedy B.C., Maier L.M., D'Amico R., Mandigo C.E., Fontana E.J., Waziri A., et al. Dynamics of central and peripheral immunomodulation in a murine glioma model. BMC Immunol. 2009, 10:11. 10.1186/1471-2172-10-11.
    • (2009) BMC Immunol. , vol.10 , pp. 11
    • Kennedy, B.C.1    Maier, L.M.2    D'Amico, R.3    Mandigo, C.E.4    Fontana, E.J.5    Waziri, A.6
  • 223
    • 84859210335 scopus 로고    scopus 로고
    • Microglia in close vicinity of glioma cells: correlation between phenotype and metabolic alterations
    • Voisin P., Bouchaud V., Merle M., Diolez P., Duffy L., Flint K., et al. Microglia in close vicinity of glioma cells: correlation between phenotype and metabolic alterations. Front. Neuroenerg. 2010, 2:131. 10.3389/fnene.2010.00131.
    • (2010) Front. Neuroenerg. , vol.2 , pp. 131
    • Voisin, P.1    Bouchaud, V.2    Merle, M.3    Diolez, P.4    Duffy, L.5    Flint, K.6
  • 224
    • 84860322833 scopus 로고    scopus 로고
    • Functional changes in myeloid-derived suppressor cells (MDSCs) during tumor growth: FKBP51 contributes to the regulation of the immunosuppressive function of MDSCs
    • Kim Y.-S., Kim Y.-J., Lee J.-M., Kim E.-K., Park Y.-J., Choe S.-K., et al. Functional changes in myeloid-derived suppressor cells (MDSCs) during tumor growth: FKBP51 contributes to the regulation of the immunosuppressive function of MDSCs. J. Immunol. 2012, 188:4226-4234. 10.4049/jimmunol.1103040.
    • (2012) J. Immunol. , vol.188 , pp. 4226-4234
    • Kim, Y.-S.1    Kim, Y.-J.2    Lee, J.-M.3    Kim, E.-K.4    Park, Y.-J.5    Choe, S.-K.6
  • 226
    • 78149330949 scopus 로고    scopus 로고
    • HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
    • Corzo C.A., Condamine T., Lu L., Cotter M.J., Youn J.-I., Cheng P., et al. HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. J. Exp. Med. 2010, 207:2439-2453. 10.1084/jem.20100587.
    • (2010) J. Exp. Med. , vol.207 , pp. 2439-2453
    • Corzo, C.A.1    Condamine, T.2    Lu, L.3    Cotter, M.J.4    Youn, J.-I.5    Cheng, P.6
  • 227
    • 79955767478 scopus 로고    scopus 로고
    • Immune modulation effects of concomitant temozolomide and radiation therapy on peripheral blood mononuclear cells in patients with glioblastoma multiforme
    • Fadul C.E., Fisher J.L., Gui J., Hampton T.H., Cote A.L., Ernstoff M.S. Immune modulation effects of concomitant temozolomide and radiation therapy on peripheral blood mononuclear cells in patients with glioblastoma multiforme. Neuro-Oncology 2011, 13:393-400. 10.1093/neuonc/noq204.
    • (2011) Neuro-Oncology , vol.13 , pp. 393-400
    • Fadul, C.E.1    Fisher, J.L.2    Gui, J.3    Hampton, T.H.4    Cote, A.L.5    Ernstoff, M.S.6
  • 228
    • 77949697909 scopus 로고    scopus 로고
    • Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice
    • Kioi M., Vogel H., Schultz G., Hoffman R.M., Harsh G.R., Brown J.M. Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. J. Clin. Invest. 2010, 120:694-705. 10.1172/JCI40283.
    • (2010) J. Clin. Invest. , vol.120 , pp. 694-705
    • Kioi, M.1    Vogel, H.2    Schultz, G.3    Hoffman, R.M.4    Harsh, G.R.5    Brown, J.M.6
  • 229
    • 79958210803 scopus 로고    scopus 로고
    • AVAglio: Phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme
    • Chinot O.L., de L.M.Rouge T., Moore N., Zeaiter A., Das A., Phillips H., et al. AVAglio: Phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme. Adv. Ther. 2011, 28:334-340. 10.1007/s12325-011-0007-3.
    • (2011) Adv. Ther. , vol.28 , pp. 334-340
    • Chinot, O.L.1    de L.M.Rouge, T.2    Moore, N.3    Zeaiter, A.4    Das, A.5    Phillips, H.6
  • 230
    • 84894194756 scopus 로고    scopus 로고
    • Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma
    • Chinot O.L., Wick W., Mason W., Henriksson R., Saran F., Nishikawa R., et al. Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma. N. Engl. J. Med. 2014, 370:709-722. 10.1056/NEJMoa1308345.
    • (2014) N. Engl. J. Med. , vol.370 , pp. 709-722
    • Chinot, O.L.1    Wick, W.2    Mason, W.3    Henriksson, R.4    Saran, F.5    Nishikawa, R.6
  • 231
    • 84894195667 scopus 로고    scopus 로고
    • Bevacizumab in glioblastoma - still much to learn
    • Fine H.A. Bevacizumab in glioblastoma - still much to learn. N. Engl. J. Med. 2014, 370:764-765. 10.1056/NEJMe1313309.
    • (2014) N. Engl. J. Med. , vol.370 , pp. 764-765
    • Fine, H.A.1
  • 232
    • 84899554487 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes
    • Gabrusiewicz K., Liu D., Cortes-Santiago N., Hossain M.B., Conrad C.A., Aldape K.D., et al. Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes. Oncotarget 2014, 5:2208-2220.
    • (2014) Oncotarget , vol.5 , pp. 2208-2220
    • Gabrusiewicz, K.1    Liu, D.2    Cortes-Santiago, N.3    Hossain, M.B.4    Conrad, C.A.5    Aldape, K.D.6
  • 233
    • 78349293679 scopus 로고    scopus 로고
    • Systemic immune suppression in glioblastoma: the interplay between CD14+HLA-DRlo/neg monocytes, tumor factors, and dexamethasone
    • Gustafson M.P., Lin Y., New K.C., Bulur P.A., O'Neill B.P., Gastineau D.A., et al. Systemic immune suppression in glioblastoma: the interplay between CD14+HLA-DRlo/neg monocytes, tumor factors, and dexamethasone. Neuro-Oncology 2010, 12:631-644. 10.1093/neuonc/noq001.
    • (2010) Neuro-Oncology , vol.12 , pp. 631-644
    • Gustafson, M.P.1    Lin, Y.2    New, K.C.3    Bulur, P.A.4    O'Neill, B.P.5    Gastineau, D.A.6
  • 234
    • 70349964695 scopus 로고    scopus 로고
    • Enhancing the efficacy of cancer vaccines in urologic oncology: new directions
    • Kusmartsev S., Vieweg J. Enhancing the efficacy of cancer vaccines in urologic oncology: new directions. Nat. Rev. Urol. 2009, 6:540-549. 10.1038/nrurol.2009.177.
    • (2009) Nat. Rev. Urol. , vol.6 , pp. 540-549
    • Kusmartsev, S.1    Vieweg, J.2
  • 235
    • 78650218768 scopus 로고    scopus 로고
    • Corosolic acid inhibits glioblastoma cell proliferation by suppressing the activation of signal transducer and activator of transcription-3 and nuclear factor-kappa B in tumor cells and tumor-associated macrophages
    • Fujiwara Y., Komohara Y., Ikeda T., Takeya M. Corosolic acid inhibits glioblastoma cell proliferation by suppressing the activation of signal transducer and activator of transcription-3 and nuclear factor-kappa B in tumor cells and tumor-associated macrophages. Cancer Sci. 2011, 102:206-211. 10.1111/j.1349-7006.2010.01772.x.
    • (2011) Cancer Sci. , vol.102 , pp. 206-211
    • Fujiwara, Y.1    Komohara, Y.2    Ikeda, T.3    Takeya, M.4
  • 236
    • 80053516019 scopus 로고    scopus 로고
    • Oleanolic acid inhibits macrophage differentiation into the M2 phenotype and glioblastoma cell proliferation by suppressing the activation of STAT3
    • Fujiwara Y., Komohara Y., Kudo R., Tsurushima K., Ohnishi K., Ikeda T., et al. Oleanolic acid inhibits macrophage differentiation into the M2 phenotype and glioblastoma cell proliferation by suppressing the activation of STAT3. Oncol. Rep. 2011, 26:1533-1537. 10.3892/or.2011.1454.
    • (2011) Oncol. Rep. , vol.26 , pp. 1533-1537
    • Fujiwara, Y.1    Komohara, Y.2    Kudo, R.3    Tsurushima, K.4    Ohnishi, K.5    Ikeda, T.6
  • 237
    • 42149111675 scopus 로고    scopus 로고
    • Inhibition of STAT3 promotes the efficacy of adoptive transfer therapy using type-1 CTLs by modulation of the immunological microenvironment in a murine intracranial glioma
    • Fujita M., Zhu X., Sasaki K., Ueda R., Low K.L., Pollack I.F., et al. Inhibition of STAT3 promotes the efficacy of adoptive transfer therapy using type-1 CTLs by modulation of the immunological microenvironment in a murine intracranial glioma. J. Immunol. 2008, 180:2089-2098.
    • (2008) J. Immunol. , vol.180 , pp. 2089-2098
    • Fujita, M.1    Zhu, X.2    Sasaki, K.3    Ueda, R.4    Low, K.L.5    Pollack, I.F.6
  • 238
    • 80052746486 scopus 로고    scopus 로고
    • Systemic delivery of neutralizing antibody targeting CCL2 for glioma therapy
    • Zhu X., Fujita M., Snyder L.A., Okada H. Systemic delivery of neutralizing antibody targeting CCL2 for glioma therapy. J. Neurooncol. 2011, 104:83-92. 10.1007/s11060-010-0473-5.
    • (2011) J. Neurooncol. , vol.104 , pp. 83-92
    • Zhu, X.1    Fujita, M.2    Snyder, L.A.3    Okada, H.4
  • 239
    • 84921929002 scopus 로고    scopus 로고
    • Antigens characteristic of M2 type pro-inflammatory macrophages are present on GBM tumor cells
    • Debinski W., Choi Y.A., Gibo D.M. Antigens characteristic of M2 type pro-inflammatory macrophages are present on GBM tumor cells. Neuro-Oncology 2013, 15:iii62-iii67. 10.1093/neuonc/not177.
    • (2013) Neuro-Oncology , vol.15 , pp. 362-367
    • Debinski, W.1    Choi, Y.A.2    Gibo, D.M.3
  • 240
    • 84890355541 scopus 로고    scopus 로고
    • CD137 stimulation and p38 MAPK inhibition improve reactivity in an in vitro model of glioblastoma immunotherapy
    • Kühnöl C., Herbarth M., Föll J., Staege M.S., Kramm C. CD137 stimulation and p38 MAPK inhibition improve reactivity in an in vitro model of glioblastoma immunotherapy. Cancer Immunol. Immunother. 2013, 62:1797-1809. 10.1007/s00262-013-1484-9.
    • (2013) Cancer Immunol. Immunother. , vol.62 , pp. 1797-1809
    • Kühnöl, C.1    Herbarth, M.2    Föll, J.3    Staege, M.S.4    Kramm, C.5
  • 241
    • 84905052545 scopus 로고    scopus 로고
    • Tumour-derived exosomes as antigen delivery carriers in dendritic cell-based immunotherapy for malignant mesothelioma
    • Mahaweni N.M., Kaijen-Lambers M.E.H., Dekkers J., Aerts J.G.J.V., Hegmans J.P.J.J. Tumour-derived exosomes as antigen delivery carriers in dendritic cell-based immunotherapy for malignant mesothelioma. J. Extracell. Vesicles 2013, 2. 10.3402/jev.v2i0.22492.
    • (2013) J. Extracell. Vesicles , vol.2
    • Mahaweni, N.M.1    Kaijen-Lambers, M.E.H.2    Dekkers, J.3    Aerts, J.G.J.V.4    Hegmans, J.P.J.J.5
  • 242
    • 0036175995 scopus 로고    scopus 로고
    • 4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicity
    • Cooper D., Bansal-Pakala P., Croft M. 4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicity. Eur. J. Immunol. 2002, 32:521-529. 10.1002/1521-4141(200202)32:2<521::AID-IMMU521>3.0.CO;2-X.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 521-529
    • Cooper, D.1    Bansal-Pakala, P.2    Croft, M.3
  • 243
    • 0035423265 scopus 로고    scopus 로고
    • 4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy
    • Cannons J.L., Lau P., Ghumman B., DeBenedette M.A., Yagita H., Okumura K., et al. 4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy. J. Immunol. 2001, 167:1313-1324.
    • (2001) J. Immunol. , vol.167 , pp. 1313-1324
    • Cannons, J.L.1    Lau, P.2    Ghumman, B.3    DeBenedette, M.A.4    Yagita, H.5    Okumura, K.6
  • 244
    • 84864285855 scopus 로고    scopus 로고
    • P38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells
    • Yeung Y.T., Bryce N.S., Adams S., Braidy N., Konayagi M., McDonald K.L., et al. p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells. J. Neurooncol. 2012, 109:35-44. 10.1007/s11060-012-0875-7.
    • (2012) J. Neurooncol. , vol.109 , pp. 35-44
    • Yeung, Y.T.1    Bryce, N.S.2    Adams, S.3    Braidy, N.4    Konayagi, M.5    McDonald, K.L.6
  • 245
    • 38049119409 scopus 로고    scopus 로고
    • P38 MAPK, microglial signaling, and neuropathic pain
    • Ji R.-R., Suter M.R. p38 MAPK, microglial signaling, and neuropathic pain. Mol. Pain 2007, 3:1-9. 10.1186/1744-8069-3-33.
    • (2007) Mol. Pain , vol.3 , pp. 1-9
    • Ji, R.-R.1    Suter, M.R.2
  • 246
    • 84870712496 scopus 로고    scopus 로고
    • (n.d.), (accessed March 31, 2014)
    • The human protein atlas (n.d.), (accessed March 31, 2014). http://www.proteinatlas.org/ENSG00000129226/cancer/tissue/glioma.
    • The human protein atlas
  • 247
    • 84870712496 scopus 로고    scopus 로고
    • (n.d.), (accessed March 31, 2014)
    • The human protein atlas (n.d.), (accessed March 31, 2014). http://www.proteinatlas.org/ENSG00000169896/cancer/tissue/glioma.
    • The human protein atlas


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