메뉴 건너뛰기




Volumn 14, Issue 7, 2014, Pages 819-825

Extracellular vesicles as a platform for 'liquid biopsy' in glioblastoma patients

Author keywords

biomarker; exosomes; extracellular vesicle; glioma; microvesicle

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE A; GELATINASE B; ISOCITRATE DEHYDROGENASE 1; MESSENGER RNA; MICRORNA; MICRORNA 21; EPIDERMAL GROWTH FACTOR RECEPTOR VIII; IDH1 PROTEIN, HUMAN; ISOCITRATE DEHYDROGENASE; MIRN21 MICRORNA, HUMAN;

EID: 84906306079     PISSN: 14737159     EISSN: 17448352     Source Type: Journal    
DOI: 10.1586/14737159.2014.943193     Document Type: Review
Times cited : (103)

References (61)
  • 1
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
    • Stupp R, Hegi ME, Mason WP, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. see comment Lancet Oncol 2009; 10(5):459-66
    • (2009) See comment Lancet Oncol , vol.10 , Issue.5 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3
  • 2
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, Van Den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352(10):987-96
    • (2005) N Engl J Med , vol.352 , Issue.10 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    Van Den Bent, M.J.3
  • 3
    • 79960801311 scopus 로고    scopus 로고
    • Current concepts and management of glioblastoma
    • Preusser M, De Ribaupierre S, Wohrer A, et al. Current concepts and management of glioblastoma. Ann Neurol 2011;70(1):9-21
    • (2011) Ann Neurol , vol.70 , Issue.1 , pp. 9-21
    • Preusser, M.1    De Ribaupierre, S.2    Wohrer, A.3
  • 5
    • 84875541362 scopus 로고    scopus 로고
    • Cerebral radiation necrosis: A review of the pathobiology, diagnosis and management considerations
    • Rahmathulla G, Marko NF, Weil RJ. Cerebral radiation necrosis: A review of the pathobiology, diagnosis and management considerations. J Clin Neurosci 2013;20(4): 485-502
    • (2013) J Clin Neurosci , vol.20 , Issue.4 , pp. 485-502
    • Rahmathulla, G.1    Marko, N.F.2    Weil, R.J.3
  • 6
    • 77649230534 scopus 로고    scopus 로고
    • Advanced imaging techniques in brain tumors
    • Spec No A S4-9
    • Law M. Advanced imaging techniques in brain tumors. Cancer Imaging 2009;9:Spec No A S4-9
    • (2009) Cancer Imaging , vol.9
    • Law, M.1
  • 8
    • 84877993023 scopus 로고    scopus 로고
    • Diagnostic yield of stereotactic needle-biopsies of sub-cubic centimeter intracranial lesions
    • Waters JD, Gonda DD, Reddy H, et al. Diagnostic yield of stereotactic needle-biopsies of sub-cubic centimeter intracranial lesions. Surg Neurol Int 2013; 4(Suppl 3):S176-81
    • (2013) Surg Neurol Int , vol.4 , Issue.SUPPL. 3
    • Waters, J.D.1    Gonda, D.D.2    Reddy, H.3
  • 9
    • 33645509873 scopus 로고    scopus 로고
    • Mutagenic potential of temozolomide in bone marrow cells in vivo
    • Geiger H, Schleimer D, Nattamai KJ, et al. Mutagenic potential of temozolomide in bone marrow cells in vivo. Blood 2006; 107(7):3010-11
    • (2006) Blood , vol.107 , Issue.7 , pp. 3010-3011
    • Geiger, H.1    Schleimer, D.2    Nattamai, K.J.3
  • 10
    • 34247855810 scopus 로고    scopus 로고
    • The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents
    • Chen CC, Taniguchi T, D'Andrea A. The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents. J Mol Med (Berl) 2007;85(5):497-509
    • (2007) J Mol Med (Berl , vol.85 , Issue.5 , pp. 497-509
    • Chen, C.C.1    Taniguchi, T.2    D'Andrea, A.3
  • 11
    • 37249019677 scopus 로고    scopus 로고
    • Mismatch repair-dependent processing of methylation damage gives rise to persistent single-stranded gaps in newly replicated DNA
    • Mojas N, Lopes M, Jiricny J. Mismatch repair-dependent processing of methylation damage gives rise to persistent single-stranded gaps in newly replicated DNA. Genes Dev 2007;21(24):3342-55
    • (2007) Genes Dev , vol.21 , Issue.24 , pp. 3342-3355
    • Mojas, N.1    Lopes, M.2    Jiricny, J.3
  • 12
    • 0038119669 scopus 로고    scopus 로고
    • Formation of DNA adducts and induction of lacI mutations in Big Blue Rat-2 cells treated with temozolomide: Implications for the treatment of low-grade adult and pediatric brain tumors
    • Bodell WJ, Gaikwad NW, Miller D, Berger MS. Formation of DNA adducts and induction of lacI mutations in Big Blue Rat-2 cells treated with temozolomide: Implications for the treatment of low-grade adult and pediatric brain tumors. Cancer Epidemiol Biomarkers Prev 2003;12(6): 545-51
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12 , Issue.6 , pp. 545-551
    • Bodell, W.J.1    Gaikwad, N.W.2    Miller, D.3    Berger, M.S.4
  • 14
    • 77649340830 scopus 로고    scopus 로고
    • A quantitative theoretical model for the development of malignancy in ductal carcinoma in situ
    • Silva AS, Gatenby RA, Gillies RJ, Yunes JA. A quantitative theoretical model for the development of malignancy in ductal carcinoma in situ. J Theor Biol 2010; 262(4):601-13
    • (2010) J Theor Biol , vol.262 , Issue.4 , pp. 601-613
    • Silva, A.S.1    Gatenby, R.A.2    Gillies, R.J.3    Yunes, J.A.4
  • 15
    • 84886938691 scopus 로고    scopus 로고
    • MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): A platform for glioblastoma biomarker development
    • Akers JC, Ramakrishnan V, Kim R, et al. MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): A platform for glioblastoma biomarker development. PLoS One 2013;8(10):e78115
    • (2013) PLoS One , vol.8 , Issue.10
    • Akers, J.C.1    Ramakrishnan, V.2    Kim, R.3
  • 16
    • 84880339763 scopus 로고    scopus 로고
    • BEAMing and droplet digital PCR analysis of mutant IDH1 mRNA in glioma patient serum and cerebrospinal fluid extracellular vesicles
    • Chen WW, Balaj L, Liau LM, et al. BEAMing and droplet digital PCR analysis of mutant IDH1 mRNA in glioma patient serum and cerebrospinal fluid extracellular vesicles. Mol Ther Nucleic Acids 2013;2: E109
    • (2013) Mol Ther Nucleic Acids , vol.2
    • Chen, W.W.1    Balaj, L.2    Liau, L.M.3
  • 17
    • 84870931536 scopus 로고    scopus 로고
    • Protein typing of circulating microvesicles allows real-Time monitoring of glioblastoma therapy
    • Shao H, Chung J, Balaj L, et al. Protein typing of circulating microvesicles allows real-Time monitoring of glioblastoma therapy. Nat Med 2012;18(12):1835-40
    • (2012) Nat Med , vol.18 , Issue.12 , pp. 1835-1840
    • Shao, H.1    Chung, J.2    Balaj, L.3
  • 18
    • 57049103401 scopus 로고    scopus 로고
    • Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
    • Skog J, Wurdinger T, Van Rijn S, et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol 2008;10(12):1470-6
    • (2008) Nat Cell Biol , vol.10 , Issue.12 , pp. 1470-1476
    • Skog, J.1    Wurdinger, T.2    Van Rijn, S.3
  • 20
    • 84874355076 scopus 로고    scopus 로고
    • Biogenesis of extracellular vesicles (EV): Exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies
    • Akers J, Gonda D, Kim R, et al. Biogenesis of extracellular vesicles (EV): Exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies. J Neurooncol 2013; 113(1):1-11
    • (2013) J Neurooncol , vol.113 , Issue.1 , pp. 1-11
    • Akers, J.1    Gonda, D.2    Kim, R.3
  • 21
    • 84899471338 scopus 로고    scopus 로고
    • Juno is the egg Izumo receptor and is essential for mammalian fertilization
    • Bianchi E, Doe B, Goulding D, Wright GJ. Juno is the egg Izumo receptor and is essential for mammalian fertilization. Nature 2014;508(7497):483-7
    • (2014) Nature , vol.508 , Issue.7497 , pp. 483-487
    • Bianchi, E.1    Doe, B.2    Goulding, D.3    Wright, G.J.4
  • 22
    • 84875846540 scopus 로고    scopus 로고
    • Neuro-oncologic applications of exosomes microvesicles and other nano-sized extracellular particles
    • Gonda DD, Akers JC, Kim R, et al. Neuro-oncologic applications of exosomes, microvesicles, and other nano-sized extracellular particles. Neurosurgery 2013; 72(4):501-10
    • (2013) Neurosurgery , vol.72 , Issue.4 , pp. 501-510
    • Gonda, D.D.1    Akers, J.C.2    Kim, R.3
  • 23
    • 0023645106 scopus 로고
    • Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes
    • Johnstone RM, Adam M, Hammond JR, et al. Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J Biol Chem 1987;262(19): 9412-20
    • (1987) J Biol Chem , vol.262 , Issue.19 , pp. 9412-9420
    • Johnstone, R.M.1    Adam, M.2    Hammond, J.R.3
  • 24
    • 78149420582 scopus 로고    scopus 로고
    • Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line
    • Ohshima K, Inoue K, Fujiwara A, et al. Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line. PLoS ONE 2010;5(10):e13247
    • (2010) PLoS ONE , vol.5 , Issue.10
    • Ohshima, K.1    Inoue, K.2    Fujiwara, A.3
  • 26
    • 77954257796 scopus 로고    scopus 로고
    • Secreted monocytic miR-150 enhances targeted endothelial cell migration
    • Zhang Y, Liu D, Chen X, et al. Secreted monocytic miR-150 enhances targeted endothelial cell migration. Mol Cell 2010; 39(1):133-44
    • (2010) Mol Cell , vol.39 , Issue.1 , pp. 133-144
    • Zhang, Y.1    Liu, D.2    Chen, X.3
  • 28
    • 0035118749 scopus 로고    scopus 로고
    • Vesicle-Associated urokinase plasminogen activator promotes invasion in prostate cancer cell lines
    • Angelucci A, D'Ascenzo S, Festuccia C, et al. Vesicle-Associated urokinase plasminogen activator promotes invasion in prostate cancer cell lines. Clin Exp Metastasis 2000;18(2):163-70
    • (2000) Clin Exp Metastasis , vol.18 , Issue.2 , pp. 163-170
    • Angelucci, A.1    D'Ascenzo, S.2    Festuccia, C.3
  • 29
    • 33645315758 scopus 로고    scopus 로고
    • Tumour-derived microvesicles carry several surface determinants and mRNA of tumour cells and transfer some of these determinants to monocytes
    • Baj-Krzyworzeka M, Szatanek R, Weglarczyk K, et al. Tumour-derived microvesicles carry several surface determinants and mRNA of tumour cells and transfer some of these determinants to monocytes. Cancer Immunol Immunother 2006;55(7):808-18
    • (2006) Cancer Immunol Immunother , vol.55 , Issue.7 , pp. 808-818
    • Baj-Krzyworzeka, M.1    Szatanek, R.2    Weglarczyk, K.3
  • 30
    • 0031760355 scopus 로고    scopus 로고
    • The amount and proteolytic content of vesicles shed by human cancer cell lines correlates with their in vitro invasiveness
    • Ginestra A, La Placa MD, Saladino F, et al. The amount and proteolytic content of vesicles shed by human cancer cell lines correlates with their in vitro invasiveness. Anticancer Res 1998;18(5A):3433-7
    • (1998) Anticancer Res , vol.18 , Issue.5 A , pp. 3433-3437
    • Ginestra, A.1    La Placa, M.D.2    Saladino, F.3
  • 31
    • 57149087260 scopus 로고    scopus 로고
    • Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes
    • Hakulinen J, Sankkila L, Sugiyama N, et al. Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes. J Cell Biochem 2008;105(5): 1211-18
    • (2008) J Cell Biochem , vol.105 , Issue.5 , pp. 1211-1218
    • Hakulinen, J.1    Sankkila, L.2    Sugiyama, N.3
  • 32
    • 59149083102 scopus 로고    scopus 로고
    • Membrane microvesicles as actors in the establishment of a favorable prostatic tumoral niche: A role for activated fibroblasts and CX3CL1-CX3CR1 axis
    • Castellana D, Zobairi F, Martinez MC, et al. Membrane microvesicles as actors in the establishment of a favorable prostatic tumoral niche: A role for activated fibroblasts and CX3CL1-CX3CR1 axis. Cancer Res 2009;69(3):785-93
    • (2009) Cancer Res , vol.69 , Issue.3 , pp. 785-793
    • Castellana, D.1    Zobairi, F.2    Martinez, M.C.3
  • 33
    • 79957879331 scopus 로고    scopus 로고
    • Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis
    • Hood JL, San RS, Wickline SA. Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis. Cancer Res 2011;71(11):3792-801
    • (2011) Cancer Res , vol.71 , Issue.11 , pp. 3792-3801
    • Hood, J.L.1    San, R.S.2    Wickline, S.A.3
  • 34
    • 84862007577 scopus 로고    scopus 로고
    • Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
    • Peinado H, Aleckovic M, Lavotshkin S, et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med 2012;18(6):883-91
    • (2012) Nat Med , vol.18 , Issue.6 , pp. 883-891
    • Peinado, H.1    Aleckovic, M.2    Lavotshkin, S.3
  • 35
    • 33746238574 scopus 로고    scopus 로고
    • Direct exosome stimulation of peripheral human T cells detected by ELISPOT
    • Admyre C, Johansson SM, Paulie S, Gabrielsson S. Direct exosome stimulation of peripheral human T cells detected by ELISPOT. Eur J Immunol 2006;36(7): 1772-81
    • (2006) Eur J Immunol , vol.36 , Issue.7 , pp. 1772-1781
    • Admyre, C.1    Johansson, S.M.2    Paulie, S.3    Gabrielsson, S.4
  • 36
    • 38749126175 scopus 로고    scopus 로고
    • Exovesicles from human activated dendritic cells fuse with resting dendritic cells, allowing them to present alloantigens
    • Obregon C, Rothen-Rutishauser B, Gitahi SK, et al. Exovesicles from human activated dendritic cells fuse with resting dendritic cells, allowing them to present alloantigens. Am J Pathol 2006;169(6): 2127-36
    • (2006) Am J Pathol , vol.169 , Issue.6 , pp. 2127-2136
    • Obregon, C.1    Rothen-Rutishauser, B.2    Gitahi, S.K.3
  • 37
    • 77955406553 scopus 로고    scopus 로고
    • Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg
    • Szajnik M, Czystowska M, Szczepanski MJ, et al. Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg). PLoS One 2010;5(7):e11469
    • (2010) PLoS One , vol.5 , Issue.7
    • Szajnik, M.1    Czystowska, M.2    Szczepanski, M.J.3
  • 38
    • 70949097575 scopus 로고    scopus 로고
    • The mechanism of budding of retroviruses from cell membranes
    • Pincetic A, Leis J. The mechanism of budding of retroviruses from cell membranes. Adv Virol 2009;2009: 6239691-9
    • (2009) Adv Virol , vol.2009 , pp. 6239691-6239699
    • Pincetic, A.1    Leis, J.2
  • 39
    • 0029989258 scopus 로고    scopus 로고
    • B lymphocytes secrete antigen-presenting vesicles
    • Raposo G, Nijman HW, Stoorvogel W, et al. B lymphocytes secrete antigen-presenting vesicles. J Exp Med 1996;183(3):1161-72
    • (1996) J Exp Med , vol.183 , Issue.3 , pp. 1161-1172
    • Raposo, G.1    Nijman, H.W.2    Stoorvogel, W.3
  • 40
    • 84874377202 scopus 로고    scopus 로고
    • Extracellular vesicles: Exosomes, microvesicles, and friends
    • Raposo GA, Stoorvogel W. Extracellular vesicles: Exosomes, microvesicles, and friends. J Cell Biol 2013;200(4):373-83
    • (2013) J Cell Biol , vol.200 , Issue.4 , pp. 373-383
    • Raposo, G.A.1    Stoorvogel, W.2
  • 41
    • 0037114287 scopus 로고    scopus 로고
    • Production and characterization of clinical grade exosomes derived from dendritic cells
    • Lamparski HG, Metha-Damani A, Yao JY, et al. Production and characterization of clinical grade exosomes derived from dendritic cells. J Immunol Methods 2002; 270(2):211-26
    • (2002) J Immunol Methods , vol.270 , Issue.2 , pp. 211-226
    • Lamparski, H.G.1    Metha-Damani, A.2    Yao, J.Y.3
  • 42
    • 0035166047 scopus 로고    scopus 로고
    • Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometry
    • Clayton A, Court J, Navabi H, et al. Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometry. J Immunol Methods 2001;247(1-2):163-74
    • (2001) J Immunol Methods , vol.247 , Issue.1-2 , pp. 163-174
    • Clayton, A.1    Court, J.2    Navabi, H.3
  • 43
    • 27844450020 scopus 로고    scopus 로고
    • Purification, characterization and biological significance of tumor-derived exosomes
    • Koga K, Matsumoto K, Akiyoshi T, et al. Purification, characterization and biological significance of tumor-derived exosomes. Anticancer Res 2005;25(6A):3703-7
    • (2005) Anticancer Res , vol.25 , Issue.6 A , pp. 3703-3707
    • Koga, K.1    Matsumoto, K.2    Akiyoshi, T.3
  • 44
    • 84890562207 scopus 로고    scopus 로고
    • Comparison of serum exosome isolation methods for microRNA profiling
    • Rekker K, Saare M, Roost AM, et al. Comparison of serum exosome isolation methods for microRNA profiling. Clin Biochem 2014;47(1-2):135-8
    • (2014) Clin Biochem , vol.47 , Issue.1-2 , pp. 135-138
    • Rekker, K.1    Saare, M.2    Roost, A.M.3
  • 45
    • 84858037808 scopus 로고    scopus 로고
    • Comparison of ultracentrifugation density gradient separation and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes
    • Tauro BJ, Greening DW, Mathias RA, et al. Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Methods 2012; 56(2):293-304
    • (2012) Methods , vol.56 , Issue.2 , pp. 293-304
    • Tauro, B.J.1    Greening, D.W.2    Mathias, R.A.3
  • 47
    • 85013222187 scopus 로고    scopus 로고
    • Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
    • Witwer KW, Buzas EI, Bemis LT, et al. Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J Extracell Vesicles 2013;2
    • (2013) J Extracell Vesicles , pp. 2
    • Witwer, K.W.1    Buzas, E.I.2    Bemis, L.T.3
  • 48
    • 43249109372 scopus 로고    scopus 로고
    • Isolation and characterization of exosomes from cell culture supernatants and biological fluids
    • Chapter 3, Unit 3 22
    • Thery C, Amigorena S, Raposo G, Clayton A. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol 2006;Chapter 3, Unit 3 22
    • (2006) Curr Protoc Cell Biol
    • Thery, C.1    Amigorena, S.2    Raposo, G.3    Clayton, A.4
  • 49
    • 84860252219 scopus 로고    scopus 로고
    • Nanoparticle tracking analysis monitors microvesicle and exosome secretion from immune cells
    • Soo CY, Song Y, Zheng Y, et al. Nanoparticle tracking analysis monitors microvesicle and exosome secretion from immune cells. Immunology 2012;136(2): 192-7
    • (2012) Immunology , vol.136 , Issue.2 , pp. 192-197
    • Soo, C.Y.1    Song, Y.2    Zheng, Y.3
  • 50
    • 84880608658 scopus 로고    scopus 로고
    • Innovation in detection of microparticles and exosomes
    • Van Der Pol E, Coumans F, Varga Z, et al. Innovation in detection of microparticles and exosomes. J Thromb Haemost 2013; 11(Suppl 1):36-45
    • (2013) J Thromb Haemost , vol.11 , Issue.SUPPL. 1 , pp. 36-45
    • Van Der Pol, E.1    Coumans, F.2    Varga, Z.3
  • 51
    • 78649939261 scopus 로고    scopus 로고
    • Tunable nano/micropores for particle detection and discrimination: Scanning ion occlusion spectroscopy
    • Roberts GS, Kozak D, Anderson W, et al. Tunable nano/micropores for particle detection and discrimination: Scanning ion occlusion spectroscopy. Small 2010;6(23): 2653-8
    • (2010) Small , vol.6 , Issue.23 , pp. 2653-2658
    • Roberts, G.S.1    Kozak, D.2    Anderson, W.3
  • 52
    • 3042757984 scopus 로고    scopus 로고
    • Immunohistochemical detection of EGFRvIII in high malignancy grade astrocytomas and evaluation of prognostic significance
    • Aldape KD, Ballman K, Furth A, et al. Immunohistochemical detection of EGFRvIII in high malignancy grade astrocytomas and evaluation of prognostic significance. J Neuropathol Exp Neurol 2004;63(7):700-7
    • (2004) J Neuropathol Exp Neurol , vol.63 , Issue.7 , pp. 700-707
    • Aldape, K.D.1    Ballman, K.2    Furth, A.3
  • 53
    • 0025114687 scopus 로고
    • Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas
    • Sugawa N, Ekstrand AJ, James CD, Collins VP. Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas. Proc Natl Acad Sci USA 1990;87(21):8602-6
    • (1990) Proc Natl Acad Sci USA , vol.87 , Issue.21 , pp. 8602-8606
    • Sugawa, N.1    Ekstrand, A.J.2    James, C.D.3    Collins, V.P.4
  • 54
    • 67349137902 scopus 로고    scopus 로고
    • The EGFRvIII variant in glioblastoma multiforme
    • Gan HK, Kaye AH, Luwor RB. The EGFRvIII variant in glioblastoma multiforme. J Clin Neurosci 2009;16(6): 748-54
    • (2009) J Clin Neurosci , vol.16 , Issue.6 , pp. 748-754
    • Gan, H.K.1    Kaye, A.H.2    Luwor, R.B.3
  • 55
    • 60849115270 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations in gliomas
    • Yan H, Parsons DW, Jin G, et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med 2009;360(8):765-73
    • (2009) N Engl J Med , vol.360 , Issue.8 , pp. 765-773
    • Yan, H.1    Parsons, D.W.2    Jin, G.3
  • 56
    • 84880300456 scopus 로고    scopus 로고
    • Oncogenic isocitrate dehydrogenase mutations: Mechanisms models and clinical opportunities
    • Cairns RA, Mak TW. Oncogenic isocitrate dehydrogenase mutations: Mechanisms, models, and clinical opportunities. Cancer Discov 2013;3(7):730-41
    • (2013) Cancer Discov , vol.3 , Issue.7 , pp. 730-741
    • Cairns, R.A.1    Mak, T.W.2
  • 57
    • 84858796263 scopus 로고    scopus 로고
    • IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
    • Turcan S, Rohle D, Goenka A, et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 2012;483(7390):479-83
    • (2012) Nature , vol.483 , Issue.7390 , pp. 479-483
    • Turcan, S.1    Rohle, D.2    Goenka, A.3
  • 58
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 2005; 65(14):6029-33
    • (2005) Cancer Res , vol.65 , Issue.14 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 59
    • 58649087374 scopus 로고    scopus 로고
    • Mir-21: A small multi-faceted RNA
    • Krichevsky AM, Gabriely G. miR-21: A small multi-faceted RNA. J Cell Mol Med 2009;13(1):39-53
    • (2009) J Cell Mol Med , vol.13 , Issue.1 , pp. 39-53
    • Krichevsky, A.M.1    Gabriely, G.2
  • 60
    • 84873028083 scopus 로고    scopus 로고
    • Circulating tumor cells: From bench to bedside
    • Balic M, Williams A, Lin H, et al. Circulating tumor cells: From bench to bedside. Annu Rev Med 2013;64:31-44
    • (2013) Annu Rev Med , vol.64 , pp. 31-44
    • Balic, M.1    Williams, A.2    Lin, H.3
  • 61
    • 84879796970 scopus 로고    scopus 로고
    • Circulating tumour cells and cell-free DNA as tools for managing breast cancer
    • De Mattos-Arruda L, Cortes J, Santarpia L, et al. Circulating tumour cells and cell-free DNA as tools for managing breast cancer. Nat Rev Clin Oncol 2013;10(7):377-89
    • (2013) Nat Rev Clin Oncol , vol.10 , Issue.7 , pp. 377-389
    • De Mattos-Arruda, L.1    Cortes, J.2    Santarpia, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.