메뉴 건너뛰기




Volumn 4, Issue 7, 2012, Pages 675-678

Treg infiltration in glioma: A hurdle for antiglioma immunotherapy

Author keywords

glioma; immunotherapy; Treg; tumor microenvironment

Indexed keywords

CANCER IMMUNOTHERAPY; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE DEFICIENCY; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; NOTE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE;

EID: 84864598740     PISSN: 1750743X     EISSN: 17507448     Source Type: Journal    
DOI: 10.2217/imt.12.64     Document Type: Note
Times cited : (18)

References (22)
  • 1
    • 84860358785 scopus 로고    scopus 로고
    • Soluble factors secreted by glioblastoma cell lines facilitate recruitment, survival, and expansion of regulatory T cells: Implications for immunotherapy
    • Crane CA, Ahn BJ, Han SJ, Parsa AT. Soluble factors secreted by glioblastoma cell lines facilitate recruitment, survival, and expansion of regulatory T cells: implications for immunotherapy. Neuro Oncol. 14(5), 584-595 (2012).
    • (2012) Neuro Oncol , vol.14 , Issue.5 , pp. 584-595
    • Crane, C.A.1    Ahn, B.J.2    Han, S.J.3    Parsa, A.T.4
  • 2
    • 81855175970 scopus 로고    scopus 로고
    • Immunotherapy for glioma: Getting closer to the clinical arena? Curr
    • Finocchiaro G, Pellegatta S. Immunotherapy for glioma: getting closer to the clinical arena? Curr. Op in Neurol. 24(6), 641-647 (2011).
    • (2011) Op in Neurol , vol.24 , Issue.6 , pp. 641-647
    • Finocchiaro, G.1    Pellegatta, S.2
  • 3
    • 70450176686 scopus 로고    scopus 로고
    • The role of tregs in glioma-mediated immunosuppression: Potential target for intervention
    • Humphries W, Wei J, Sampson JH, Heimberger AB. The role of tregs in glioma-mediated immunosuppression: potential target for intervention. Neurosurg. Clin. N. Am. 21(1), 125-137 (2010).
    • (2010) Neurosurg. Clin. N. Am. , vol.21 , Issue.1 , pp. 125-137
    • Humphries, W.1    Wei, J.2    Sampson, J.H.3    Heimberger, A.B.4
  • 5
    • 77955658133 scopus 로고    scopus 로고
    • Prognostic signifcance and mechanism of Treg infltration in human brain tumors
    • Jacobs JF, Idema AJ, Bol KF et al. Prognostic signifcance and mechanism of Treg infltration in human brain tumors. J. Neuroimmunol. 225(1-2), 195-199 (2010).
    • (2010) J. Neuroimmunol. , vol.225 , Issue.1-2 , pp. 195-199
    • Jacobs, J.F.1    Idema, A.J.2    Bol, K.F.3
  • 6
    • 77954721060 scopus 로고    scopus 로고
    • Regulatory T cells in tumor immunity
    • Nishikawa H, Sakaguchi S. Regulatory T cells in tumor immunity. Int. J. Cancer 127(4), 759-767 (2010).
    • (2010) Int. J. Cancer , vol.127 , Issue.4 , pp. 759-767
    • Nishikawa, H.1    Sakaguchi, S.2
  • 7
    • 35748975652 scopus 로고    scopus 로고
    • Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy
    • Jordan JT, Sun W, Hussain SF, Deangulo G, Prabhu SS, Heimberger AB. Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy. Cancer Immunol. Immunother. 57(1), 123-131 (2008).
    • (2008) Cancer Immunol. Immunother. , vol.57 , Issue.1 , pp. 123-131
    • Jordan, J.T.1    Sun, W.2    Hussain, S.F.3    Deangulo, G.4    Prabhu, S.S.5    Heimberger, A.B.6
  • 9
  • 10
    • 69949127667 scopus 로고    scopus 로고
    • DC vaccination with anti-CD25 treatment leads to long-term immunity against experimental glioma experimental glioma
    • Maes W, Rosas GG, Verbinnen B et al. DC vaccination with anti-CD25 treatment leads to long-term immunity against experimental glioma experimental glioma. Neuro Oncol. 11(5), 529-542 (2009).
    • (2009) Neuro Oncol. , vol.11 , Issue.5 , pp. 529-542
    • Maes, W.1    Rosas, G.G.2    Verbinnen, B.3
  • 12
    • 39149097490 scopus 로고    scopus 로고
    • Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: Case study
    • Heimberger AB, Sun W, Hussain SF et al. Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: case study. Neuro Oncol. 10(1), 98-103 (2008).
    • (2008) Neuro Oncol , vol.10 , Issue.1 , pp. 98-103
    • Heimberger, A.B.1    Sun, W.2    Hussain, S.F.3
  • 13
    • 33847368549 scopus 로고    scopus 로고
    • Metronomic cyclophosphamide regimen selectively depletes CD4 + CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
    • Ghiringhelli F, Menard C, Puig PE et al. Metronomic cyclophosphamide regimen selectively depletes CD4 + CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients. Cancer Immunol. Immunother. 56(5), 641-648 (2007).
    • (2007) Cancer Immunol. Immunother. , vol.56 , Issue.5 , pp. 641-648
    • Ghiringhelli, F.1    Menard, C.2    Puig, P.E.3
  • 14
  • 15
    • 84863195770 scopus 로고    scopus 로고
    • Potentiation of a p53-SLP vaccine by cyclophosphamide in ovarian cancer: A single-arm Phase II study
    • doi:10.1002/ijc.27388 Epub ahead of print
    • Vermeij R, Leffers N, Hoogeboom BN et al. Potentiation of a p53-SLP vaccine by cyclophosphamide in ovarian cancer: a single-arm Phase II study. Int. J. Cancer doi:10.1002/ijc.27388 (2011) (Epub ahead of print).
    • (2011) Int. J. Cancer
    • Vermeij, R.1    Leffers, N.2    Hoogeboom, B.N.3
  • 16
    • 82255167661 scopus 로고    scopus 로고
    • Phase I-II study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell cancer
    • Huijts CM, Santegoets SJ, van den Eertwegh AJ et al. Phase I-II study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell cancer. BMC Cancer 11(1), 505 (2011).
    • (2011) BMC Cancer , vol.11 , Issue.1 , pp. 505
    • Huijts, C.M.1    Santegoets, S.J.2    Van Den Eertwegh, A.J.3
  • 17
    • 84860815596 scopus 로고    scopus 로고
    • Metronomic cyclophosphamide treatment in metastasized breast cancer patients: Immunological effects and clinical outcome
    • Ge Y, Domschke C, Stoiber N et al. Metronomic cyclophosphamide treatment in metastasized breast cancer patients: immunological effects and clinical outcome. Cancer Immunol. Immunother. 61(3), 353-362 (2011).
    • (2011) Cancer Immunol. Immunother. , vol.61 , Issue.3 , pp. 353-362
    • Ge, Y.1    Domschke, C.2    Stoiber, N.3
  • 18
    • 79551514818 scopus 로고    scopus 로고
    • Cyclophosphamide induces differentiation of Th17 cells in cancer patients
    • Viaud S, Flament C, Zoubir M et al. Cyclophosphamide induces differentiation of Th17 cells in cancer patients. Cancer Res. 71(3), 661-665 (2011).
    • (2011) Cancer Res , vol.71 , Issue.3 , pp. 661-665
    • Viaud, S.1    Flament, C.2    Zoubir, M.3
  • 19
    • 0021247642 scopus 로고
    • Gamma-irradiation facilitates the expression of adoptive immunity against established tumors by eliminating suppressor T cells
    • North RJ. Gamma-irradiation facilitates the expression of adoptive immunity against established tumors by eliminating suppressor T cells. Cancer Immunol. Immunother. 16(3), 175-181 (1984).
    • (1984) Cancer Immunol. Immunother. , vol.16 , Issue.3 , pp. 175-181
    • North, R.J.1
  • 20
    • 84870985481 scopus 로고    scopus 로고
    • Integration of autologous dendritic cell-based immunotherapy in the standard of care treatment for patients with newly diagnosed glioblastoma: Results of the HGG-2006 Phase I/II trial
    • doi:10.1007/s00262-012-1261-1 Epub ahead of print
    • Ardon H, Van Gool S, Verschuere T et al. Integration of autologous dendritic cell-based immunotherapy in the standard of care treatment for patients with newly diagnosed glioblastoma: results of the HGG-2006 Phase I/II trial. Cancer Immunol. Immunother. doi:10.1007/s00262-012-1261-1 (2012) (Epub ahead of print).
    • (2012) Cancer Immunol. Immunother
    • Ardon, H.1    Van Gool, S.2    Verschuere, T.3
  • 22
    • 84870982871 scopus 로고    scopus 로고
    • Stratifcation according to HGG-IMMUNO RPA model predicts outcome in a large group of patients with relapsed malignant glioma treated by postoperative dendritic cell vaccination
    • doi:10.1007/s00262-012-1271-z Epub ahead of print
    • De Vleeschouwer S, Ardon H, Van Calenbergh F et al. Stratifcation according to HGG-IMMUNO RPA model predicts outcome in a large group of patients with relapsed malignant glioma treated by postoperative dendritic cell vaccination. Cancer Immunol. Immunother. doi:10.1007/s00262-012-1271-z (2012) (Epub ahead of print).
    • (2012) Cancer Immunol. Immunother
    • De Vleeschouwer, S.1    Ardon, H.2    Van Calenbergh, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.