Change in platelet levels during radiotherapy with concurrent and adjuvant temozolomide for the treatment of glioblastoma: A novel prognostic factor for survival

Journal of Cancer Research and Clinical Oncology

Volumn 138, Issue 10, 2012, Pages 1683-1688

  Williams, Matt ^a,b   Liu, Zi Wei ^a   Woolf, David ^a   Hargreaves, Sarah ^a   Michalarea, Vasiliki ^a   Menashy, Rebecca ^a   Kooner, Ishminder ^a   Wilson, Elena ^a,b  

^a ROYAL FREE HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE HOSPITAL   (United Kingdom)

Author keywords

Glioblastoma; Platelets; Prognosis; Survival; Temozolomide

Indexed keywords

ANTIEMETIC AGENT; COTRIMOXAZOLE; STEROID; TEMOZOLOMIDE;

ADJUVANT THERAPY; ADULT; ARTICLE; CANCER ADJUVANT THERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER PROGNOSIS; CANCER SURVIVAL; CHEMORADIOTHERAPY; FEMALE; GLIOBLASTOMA; HEMATOLOGICAL PARAMETERS; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PREDICTOR VARIABLE; PRIORITY JOURNAL; RADIATION DOSE; RETROSPECTIVE STUDY; STEROID THERAPY; SURVIVAL RATE; THROMBOCYTE COUNT; TREATMENT DURATION; TREATMENT RESPONSE; TREND STUDY;

ANTINEOPLASTIC AGENTS, ALKYLATING; BLOOD PLATELETS; BRAIN NEOPLASMS; CHEMOTHERAPY, ADJUVANT; COMBINED MODALITY THERAPY; DACARBAZINE; FEMALE; GLIOBLASTOMA; HUMANS; MALE; MIDDLE AGED; PLATELET COUNT; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 84866734421     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-012-1243-x     Document Type: Article

References (22)

1. Athanassiou H, Synodinou M, Maragoudakis E et al (2005) Randomized phase II study of temozolomide and radiotherapy compared with radiotherapy alone in newly diagnosed glioblas-toma multiforme. J Clin Oncol 23(10):2372-2377
2. Bauchet L, Mathieu-Daudé H, Fabbro-Peray P et al (2010) Oncological patterns of care and outcome for 952 patients with newly diagnosed glioblastoma in 2004. Neuro Oncol 12(7):725-735
3. Brockmann MA, Giese A, Mueller K et al (2007) Preoperative thrombocytosis predicts poor survival in patients with glioblas-toma. Neuro Oncol 9(3):335-342
4. Central brain tumour registry of the United States (2011) CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2004-2007. Available at http://www.cbtrus.org. Accessed 1 Oct 2011
5. Fine HA, Dear KB, Loeffler JS et al (1993) Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults. Cancer 71(8):2585-2597
6. Gerber DE, Grossman SA, Zeltzman M et al (2007) The impact of thrombocytopenia from temozolomide and radiation in newly diagnosed adults with high-grade gliomas. Neuro Oncol 9(1):47-52
7. Gorelick C, Andikyan V, Mack M et al (2009) Prognostic significance of preoperative thrombocytosis in patients with endometrial carcinoma in an inner-city population. Int J Gynecol Cancer 19(8):1384-1389
8. Hargreaves SJ, Williams M, Liu Z et al (2010) Survival in patients receiving radiotherapy plus concomitant and adjuvant temozol-omide (RCAT) for glioblastoma (GBM). Int J Radiat Oncol Biol Phys 78(3):S281-S282
9. Helseth R, Helseth E, Johannesen TB et al (2010) Overall survival, prognostic factors, and repeated surgery in a consecutive series of 516 patients with glioblastoma multiforme. Acta Neurol Scand 122(3):159-167
10. Herbert C, Williams M, Sawyer H et al (2011) Treatment of glioblastoma multiforme with radiotherapy and concomitant and adjuvant temozolomide: translation of randomised controlled trial evidence into routine clinical practice. Clin Oncol (R Coll Radiol) 23(5):372-373
11. Ikeda M, Furukawa H, Imamura H et al (2002) Poor prognosis associated with thrombocytosis in patients with gastric cancer. Ann Surg Oncol 9(3):287-291
12. Nakayama Y, Sueishi K, Oka K et al (1998) Stromal angiogenesis in human glioma: a role of platelet-derived endothelial cell growth factor. Surg Neurol 49(2):181-187
13. Nolte I, Przibylla H, Bostel T et al (2008) Tumor-platelet interactions: glioblastoma growth is accompanied by increasing platelet counts. Clin Neurol Neurosurg 110(4):339-342
14. Perry J, Laperriere N, Zuraw L et al (2007) Neuro-oncology Disease Site Group; Cancer Care Ontario Program in Evidence-Based Care. Adjuvant chemotherapy for adults with malignant glioma: a systematic review. Can J Neurol Sci 34(4):402-410
15. Sasaki K, Kawai K, Tsuno NH et al (2012) Impact of preoperative thrombocytosis on the survival of patients with primary colorec-tal cancer. World J Surg 36(1):192-200. doi:10.1007/s00268-011-1329-7
16. Stupp R, Dietrich PY, Ostermann Kraljevic S et al (2002) Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide. J Clin Oncol 20(5):1375-1382
17. Stupp R, Mason WP, van den Bent MJ et al (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352(10):987-996
18. Suzuki M, Iizasa T, Ko Eitetu et al (2002) Serum endostatin correlates with progression and prognosis of non-small cell lung cancer. Lung Cancer 35(1):29-34
19. R Development Core Team (2011) R: a language and environment for statistical computing. R Foundation for Statistical Computing Vienna, Austria. Available from: http://www.R-project.org/. Accessed Jan 2011
20. van Genugten JA, Leffers P, Baumert BG et al (2010) Effectiveness of temozolomide for primary glioblastoma multiform in routine clinical practice. J Neuro Oncol 96(2):249-257
21. Villano JL, Seery TE, Bressler LR (2009) Temozolomide in malignant gliomas: current use and future targets. Cancer Chemother Pharmacol 64(4):647-655
22. Walker MD, Alexander E Jr, Hunt WE et al (1978) Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. J Neurosurg 49(3):333-343