Importance of direct macrophage - Tumor cell interaction on progression of human glioma

Cancer Science

Volumn 103, Issue 12, 2012, Pages 2165-2172

  Komohara, Yoshihiro ^a   Horlad, Hasita ^a   Ohnishi, Koji ^a   Fujiwara, Yukio ^a   Bai, Bing ^a   Nakagawa, Takenobu ^a   Suzu, Shinya ^b   Nakamura, Hideo ^a   Kuratsu, Jun Ichi ^a   Takeya, Motohiro ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; SMALL INTERFERING RNA; STAT3 PROTEIN;

ARTICLE; CELL INTERACTION; CELL TYPE; COCULTURE; CONTROLLED STUDY; DOWN REGULATION; GENE ACTIVATION; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SCREENING TEST; TUMOR ASSOCIATED LEUKOCYTE;

ADULT; AGED; CELL LINE, TUMOR; CELL PROLIFERATION; COCULTURE TECHNIQUES; DOWN-REGULATION; FEMALE; GLIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MALE; MICROGLIA; MIDDLE AGED; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; RNA, SMALL INTERFERING;

EID: 84870657385     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/cas.12015     Document Type: Article

References (40)

1. Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 2004; 4: 71-8.
2. Sica A, Schioppa T, Mantovani A, Allavena P. Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer 2006; 42: 717-27.
3. Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003; 3: 23-35.
4. Jensen TO, Schmidt H, Moller HJ et al. Macrophage markers in serum and tumor have prognostic impact in American Joint Committee on Cancer stage I/II melanoma. J Clin Oncol 2009; 27: 3330-7.
5. Espinosa I, Beck AH, Lee CH et al. Coordinate expression of colony-stimulating factor-1 and colony-stimulating factor-1-related proteins is associated with poor prognosis in gynecological and nongynecological leiomyosarcoma. Am J Pathol 2009; 174: 2347-56.
6. Komohara Y, Ohnishi K, Kuratsu J, Takeya M. Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas. J Pathol 2008; 216: 15-24.
7. Kurahara H, Shinchi H, Mataki Y et al. Significance of M2-polarized tumor-associated macrophage in pancreatic cancer. J Surg Res 2009; 167: e211-9.
8. Hasita H, Komohara Y, Okabe H et al. Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma. Cancer Sci 2010; 101: 1913-9.
9. Komohara Y, Hasita H, Ohnishi K et al. Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma. Cancer Sci 2011; 102: 1424-31.
10. Niino D, Komohara Y, Murayama T et al. Ratio of M2 macrophage expression is closely associated with poor prognosis for Angioimmunoblastic T-cell lymphoma (AITL). Pathol Int 2010; 60: 278-83.
11. Steidl C, Lee T, Shah SP et al. Tumor-associated macrophages and survival in classic Hodgkin's lymphoma. N Engl J Med 2010; 362: 875-85.
12. Nishie A, Ono M, Shono T et al. Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas. Clin Cancer Res 1999; 5: 1107-13.
13. Hirano H, Tanioka K, Yokoyama S, Akiyama S, Kuratsu J. Angiogenic effect of thymidine phosphorylase on macrophages in glioblastoma multiforme. J Neurosurg 2001; 95: 89-95.
14. Hussain SF, Yang D, Suki D, Aldape K, Grimm E, Heimberger AB. The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses. Neuro Oncol 2006; 8: 261-79.
15. Zhai H, Heppner FL, Tsirka SE. Microglia/macrophages promote glioma progression. Glia 2011; 59: 472-85.
16. Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol 2007; 7: 41-51.
17. Yoshimura A. Signal transduction of inflammatory cytokines and tumor development. Cancer Sci 2006; 97: 439-47.
18. Abou-Ghazal M, Yang DS, Qiao W et al. The incidence, correlation with tumor-infiltrating inflammation, and prognosis of phosphorylated STAT3 expression in human gliomas. Clin Cancer Res 2008; 14: 8228-35.
19. Page BD, Ball DP, Gunning PT. Signal transducer and activator of transcription 3 inhibitors: a patent review. Expert Opin Ther Pat 2011; 21: 65-83.
20. Cheng F, Wang HW, Cuenca A et al. A critical role for Stat3 signaling in immune tolerance. Immunity 2003; 19: 425-36.
21. Wu L, Du H, Li Y, Qu P, Yan C. Signal transducer and activator of transcription 3 (Stat3C) promotes myeloid-derived suppressor cell expansion and immune suppression during lung tumorigenesis. Am J Pathol 2011; 179: 2131-41.
22. Fujita M, Kohanbash G, Fellows-Mayle W et al. COX-2 blockade suppresses gliomagenesis by inhibiting myeloid-derived suppressor cells. Cancer Res 2011; 71: 2664-74.
23. Hussain SF, Kong LY, Jordan J et al. A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients. Cancer Res 2007; 67: 9630-6.
24. Chihara T, Suzu S, Hassan R et al. IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation. Cell Death Differ 2010; 17: 1917-27.
25. Takaishi K, Komohara Y, Tashiro H et al. Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation. Cancer Sci 2010; 101: 2128-36.
26. Horikawa T, Komohara Y, Kiyota E, Terasaki Y, Takagi K, Takeya M. Detection of guinea pig macrophages by a new CD68 monoclonal antibody, PM-1K. J Mol Histol 2006; 37: 15-25.
27. Komohara Y, Horlad H, Ohnishi K et al. M2 macrophage/microglial cells induce activation of Stat3 in primary central nervous system lymphoma. J Clin Exp Hematop 2011; 51: 93-9.
28. Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest 2012; 122: 787-95.
29. Baay M, Brouwer A, Pauwels P, Peeters M, Lardon F. Tumor cells and tumor-associated macrophages: secreted proteins as potential targets for therapy. Clin Dev Immunol 2011; 2011: 565187.
30. Zheng Y, Cai Z, Wang S et al. Macrophages are an abundant component of myeloma microenvironment and protect myeloma cells from chemotherapy drug-induced apoptosis. Blood 2009; 114: 3625-8.
31. Zhang L, Alizadeh D, Van Handel M, Kortylewski M, Yu H, Badie B. Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice. Glia 2009; 57: 1458-67.
32. Fujita M, Zhu X, Sasaki K et al. Inhibition of STAT3 promotes the efficacy of adoptive transfer therapy using type-1 CTLs by modulation of the immunological microenvironment in a murine intracranial glioma. J Immunol 2008; 180: 2089-98.
33. Douglass TG, Driggers L, Zhang JG et al. Macrophage colony stimulating factor: not just for macrophages anymore! A gateway into complex biologies. Int Immunopharmacol 2008; 8: 1354-76.
34. Stein J, Borzillo GV, Rettenmier CW. Direct stimulation of cells expressing receptors for macrophage colony-stimulating factor (CSF-1) by a plasma membrane-bound precursor of human CSF-1. Blood 1990; 76: 1308-14.
35. Novak U, Harpur AG, Paradiso L et al. Colony-stimulating factor 1-induced STAT1 and STAT3 activation is accompanied by phosphorylation of Tyk2 in macrophages and Tyk2 and JAK1 in fibroblasts. Blood 1995; 86: 2948-56.
36. Sherry MM, Reeves A, Wu JK, Cochran BH. STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells. Stem Cells 2009; 27: 2383-92.
37. Wu A, Wei J, Kong LY et al. Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro Oncol 2010; 12: 1113-25.
38. Kubota Y, Takubo K, Shimizu T et al. M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med 2009; 206: 1089-102.
39. Priceman SJ, Sung JL, Shaposhnik Z et al. Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy. Blood 2010; 115: 1461-71.
40. Coniglio SJ, Eugenin E, Dobrenis K et al. Microglial stimulation of glioblastoma invasion involves EGFR and CSF-1R signaling. Mol Med 2012; 18: 519-27.