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Volumn 35, Issue 9, 2014, Pages 8425-8438

Extracellular vesicles shed by glioma cells: pathogenic role and clinical value

Author keywords

Biomarker; Exosome; Extracellular vesicle; Glioma; Microvesicle; Tumorigenesis

Indexed keywords

TUMOR ANTIGEN; TUMOR MARKER; MICRORNA;

EID: 84919845773     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1007/s13277-014-2262-9     Document Type: Review
Times cited : (76)

References (143)
  • 1
    • 84870173770 scopus 로고    scopus 로고
    • Multivesicular body morphogenesis
    • PID: 22831642, COI: 1:CAS:528:DC%2BC38XhslagtbrO, PMID: 22831642
    • Hanson PI, Cashikar A. Multivesicular body morphogenesis. Annu Rev Cell Dev Biol. 2012;28:337–62. PMID: 22831642.
    • (2012) Annu Rev Cell Dev Biol , vol.28 , pp. 337-362
    • Hanson, P.I.1    Cashikar, A.2
  • 2
    • 84859593755 scopus 로고    scopus 로고
    • Differential requirements of mammalian ESCRTs in multivesicular body formation, virus budding and cell division
    • PID: 22340600, COI: 1:CAS:528:DC%2BC38XmsVejsL8%3D, PMID: 22340600
    • Morita E. Differential requirements of mammalian ESCRTs in multivesicular body formation, virus budding and cell division. FEBS J. 2012;279(8):1399–406. PMID: 22340600.
    • (2012) FEBS J , vol.279 , Issue.8 , pp. 1399-1406
    • Morita, E.1
  • 3
    • 39549095341 scopus 로고    scopus 로고
    • Mechanisms for enveloped virus budding: can some viruses do without an ESCRT?
    • PID: 18063004, COI: 1:CAS:528:DC%2BD1cXisVWitbo%3D, PMID: 18063004
    • Chen BJ, Lamb RA. Mechanisms for enveloped virus budding: can some viruses do without an ESCRT? Virology. 2008;372(2):221–32. PMID: 18063004.
    • (2008) Virology , vol.372 , Issue.2 , pp. 221-232
    • Chen, B.J.1    Lamb, R.A.2
  • 4
    • 79251592263 scopus 로고    scopus 로고
    • Multivesicular bodies in neurons: distribution, protein content, and trafficking functions
    • PMID: 21216273
    • Von Bartheld CS, Altick AL. Multivesicular bodies in neurons: distribution, protein content, and trafficking functions. Prog Neurobiol. 2011;93(3):313–40. PMID: 21216273.
    • (2011) Prog Neurobiol , vol.93 , Issue.3 , pp. 313-340
    • Von Bartheld, C.S.1    Altick, A.L.2
  • 5
    • 0035877018 scopus 로고    scopus 로고
    • Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles
    • PID: 11390481, PMID: 11390481
    • Théry C, Boussac M, Veron P, Ricciardi-Castagnoli P, Raposo G, Garin J, et al. Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. J Immunol. 2001;166(12):7309–18. PMID: 11390481.
    • (2001) J Immunol , vol.166 , Issue.12 , pp. 7309-7318
    • Théry, C.1    Boussac, M.2    Veron, P.3    Ricciardi-Castagnoli, P.4    Raposo, G.5    Garin, J.6
  • 6
    • 40049112564 scopus 로고    scopus 로고
    • Ceramide triggers budding of exosome vesicles into multivesicular endosomes
    • PID: 18309083, COI: 1:CAS:528:DC%2BD1cXisVSksLY%3D, PMID: 18309083
    • Trajkovic K, Hsu C, Chiantia S, Rajendran L, Wenzel D, Wieland F, et al. Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science. 2008;319(5867):1244–7. PMID: 18309083.
    • (2008) Science , vol.319 , Issue.5867 , pp. 1244-1247
    • Trajkovic, K.1    Hsu, C.2    Chiantia, S.3    Rajendran, L.4    Wenzel, D.5    Wieland, F.6
  • 7
    • 34948874323 scopus 로고    scopus 로고
    • T cell-induced secretion of MHC class II-peptide complexes on B cell exosomes
    • PID: 17805347, COI: 1:CAS:528:DC%2BD2sXhtFWiu7rK, PMID: 17805347
    • Muntasell A, Berger AC, Roche PA. T cell-induced secretion of MHC class II-peptide complexes on B cell exosomes. EMBO J. 2007;26(19):4263–72. PMID: 17805347.
    • (2007) EMBO J , vol.26 , Issue.19 , pp. 4263-4272
    • Muntasell, A.1    Berger, A.C.2    Roche, P.A.3
  • 8
    • 77953154769 scopus 로고    scopus 로고
    • Cellular internalization of exosomes occurs through phagocytosis
    • COI: 1:CAS:528:DC%2BC3cXlt1Kis7Y%3D, PMID: 20136776
    • Feng D, Zhao WL, Ye YY, Bai XC, Liu RQ, Chang LF, et al. Cellular internalization of exosomes occurs through phagocytosis. Traffic. 2010;11(5):675–87. PMID: 20136776.
    • (2010) Traffic , vol.11 , Issue.5 , pp. 675-687
    • Feng, D.1    Zhao, W.L.2    Ye, Y.Y.3    Bai, X.C.4    Liu, R.Q.5    Chang, L.F.6
  • 9
    • 67649512000 scopus 로고    scopus 로고
    • Cell-derived microparticles: a new challenge in neuroscience
    • COI: 1:CAS:528:DC%2BD1MXovV2mt7o%3D, PMID: 19457085
    • Doeuvre L, Plawinski L, Toti F, Anglés-Cano E. Cell-derived microparticles: a new challenge in neuroscience. J Neurochem. 2009;110(2):457–68. PMID: 19457085.
    • (2009) J Neurochem , vol.110 , Issue.2 , pp. 457-468
    • Doeuvre, L.1    Plawinski, L.2    Toti, F.3    Anglés-Cano, E.4
  • 10
    • 67650531887 scopus 로고    scopus 로고
    • Microvesicles: messengers and mediators of tumor progression
    • PID: 19535896, COI: 1:CAS:528:DC%2BC3cXovFyrtg%3D%3D, PMID: 19535896
    • Al-Nedawi K, Meehan B, Rak J. Microvesicles: messengers and mediators of tumor progression. Cell Cycle. 2009;8(13):2014–8. PMID: 19535896.
    • (2009) Cell Cycle , vol.8 , Issue.13 , pp. 2014-2018
    • Al-Nedawi, K.1    Meehan, B.2    Rak, J.3
  • 11
    • 84866425004 scopus 로고    scopus 로고
    • Microglial microvesicle secretion and intercellular signaling
    • PID: 22661954, COI: 1:CAS:528:DC%2BC38XptV2itro%3D, PMID: 22661954
    • Turola E, Furlan R, Bianco F, Matteoli M, Verderio C. Microglial microvesicle secretion and intercellular signaling. Front Physiol. 2012;3:149. PMID: 22661954.
    • (2012) Front Physiol , vol.3 , pp. 149
    • Turola, E.1    Furlan, R.2    Bianco, F.3    Matteoli, M.4    Verderio, C.5
  • 12
    • 76949101800 scopus 로고    scopus 로고
    • Astrocytes and glioblastoma cells release exosomes carrying mtDNA
    • PID: 19680595, COI: 1:CAS:528:DC%2BD1MXhsFWmurjF, PMID: 19680595
    • Guescini M, Genedani S, Stocchi V, Agnati LF. Astrocytes and glioblastoma cells release exosomes carrying mtDNA. J Neural Transm. 2010;117(1):1–4. PMID: 19680595.
    • (2010) J Neural Transm , vol.117 , Issue.1 , pp. 1-4
    • Guescini, M.1    Genedani, S.2    Stocchi, V.3    Agnati, L.F.4
  • 13
    • 33847707857 scopus 로고    scopus 로고
    • Nerve cell death types in the edematous human cerebral cortex
    • PID: 17283964, PMID: 17283964
    • Castejón OJ, Arismendi GJ. Nerve cell death types in the edematous human cerebral cortex. J Submicrosc Cytol Pathol. 2006;38(1):21–36. PMID: 17283964.
    • (2006) J Submicrosc Cytol Pathol , vol.38 , Issue.1 , pp. 21-36
    • Castejón, O.J.1    Arismendi, G.J.2
  • 14
    • 73649124551 scopus 로고    scopus 로고
    • Death-associated protein kinase (DAPK) and signal transduction: blebbing in programmed cell death
    • PID: 19878312, COI: 1:CAS:528:DC%2BC3cXhs1Gmsw%3D%3D, PMID: 19878312
    • Bovellan M, Fritzsche M, Stevens C, Charras G. Death-associated protein kinase (DAPK) and signal transduction: blebbing in programmed cell death. FEBS J. 2010;277(1):58–65. PMID: 19878312.
    • (2010) FEBS J , vol.277 , Issue.1 , pp. 58-65
    • Bovellan, M.1    Fritzsche, M.2    Stevens, C.3    Charras, G.4
  • 15
    • 43249109372 scopus 로고    scopus 로고
    • Chapter 3:Unit 3.22
    • Théry C, Amigorena S, Raposo G, Clayton A. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol. 2006; Chapter 3:Unit 3.22. PMID: 18228490.
    • (2006) PMID
    • Théry, C.1    Amigorena, S.2    Raposo, G.3    Isolation, C.A.4
  • 16
    • 33644927263 scopus 로고    scopus 로고
    • Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane
    • PID: 16533950, COI: 1:CAS:528:DC%2BD28XisFKisLs%3D, PMID: 16533950
    • Booth AM, Fang Y, Fallon JK, Yang JM, Hildreth JE, Gould SJ. Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane. J Cell Biol. 2006;172(6):923–35. PMID: 16533950.
    • (2006) J Cell Biol , vol.172 , Issue.6 , pp. 923-935
    • Booth, A.M.1    Fang, Y.2    Fallon, J.K.3    Yang, J.M.4    Hildreth, J.E.5    Gould, S.J.6
  • 17
    • 84899031073 scopus 로고    scopus 로고
    • Glioma-associated stem cells: a novel class of tumor-supporting cells able to predict prognosis of human low-grade gliomas
    • PID: 24375787, COI: 1:CAS:528:DC%2BC2cXps12kt7c%3D, PMID: 24375787
    • Bourkoula E, Mangoni D, Ius T, Pucer A, Isola M, Musiello D, et al. Glioma-associated stem cells: a novel class of tumor-supporting cells able to predict prognosis of human low-grade gliomas. Stem Cells. 2014;32:1239–53. PMID: 24375787.
    • (2014) Stem Cells , vol.32 , pp. 1239-1253
    • Bourkoula, E.1    Mangoni, D.2    Ius, T.3    Pucer, A.4    Isola, M.5    Musiello, D.6
  • 18
    • 80054801476 scopus 로고    scopus 로고
    • Oligodendroglioma cells shed microvesicles which contain TRAIL as well as molecular chaperones and induce cell death in astrocytes
    • PID: 21842121, COI: 1:CAS:528:DC%2BC3MXhs1SlsLvP, PMID: 21842121
    • Lo Cicero A, Schiera G, Proia P, Saladino P, Savettieri G, Di Liegro CM, et al. Oligodendroglioma cells shed microvesicles which contain TRAIL as well as molecular chaperones and induce cell death in astrocytes. Int J Oncol. 2011;39(6):1353–7. PMID: 21842121.
    • (2011) Int J Oncol , vol.39 , Issue.6 , pp. 1353-1357
    • Lo Cicero, A.1    Schiera, G.2    Proia, P.3    Saladino, P.4    Savettieri, G.5    Di Liegro, C.M.6
  • 19
    • 84870931536 scopus 로고    scopus 로고
    • Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy
    • COI: 1:CAS:528:DC%2BC38Xhs1CktrnJ, PMID: 23142818
    • Shao H, Chung J, Balaj L, Charest A, Bigner DD, Carter BS, et al. Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy. Nat Med. 2012;18(12):1835–40. PMID: 23142818.
    • (2012) Nat Med , vol.18 , Issue.12 , pp. 1835-1840
    • Shao, H.1    Chung, J.2    Balaj, L.3    Charest, A.4    Bigner, D.D.5    Carter, B.S.6
  • 20
    • 0742287264 scopus 로고    scopus 로고
    • Heat shock protein 90
    • PID: 14624223, COI: 1:CAS:528:DC%2BD3sXptVCmsbg%3D, PMID: 14624223
    • Neckers L, Ivy SP. Heat shock protein 90. Curr Opin Oncol. 2003;15(6):419–24. PMID: 14624223.
    • (2003) Curr Opin Oncol , vol.15 , Issue.6 , pp. 419-424
    • Neckers, L.1    Ivy, S.P.2
  • 21
    • 84899948104 scopus 로고    scopus 로고
    • Regulation of exosome release by glycosphingolipids and flotillins
    • PID: 24605801, COI: 1:CAS:528:DC%2BC2cXntFCmsr8%3D, PMID: 24605801
    • Phuyal S, Hessvik NP, Skotland T, Sandvig K, Llorente A. Regulation of exosome release by glycosphingolipids and flotillins. FEBS J. 2014;281(9):2214–27. PMID: 24605801.
    • (2014) FEBS J , vol.281 , Issue.9 , pp. 2214-2227
    • Phuyal, S.1    Hessvik, N.P.2    Skotland, T.3    Sandvig, K.4    Llorente, A.5
  • 22
    • 0035207920 scopus 로고    scopus 로고
    • Complexes of tetraspanins with integrins: more than meets the eye
    • PMID: 11739647
    • Berditchevski F. Complexes of tetraspanins with integrins: more than meets the eye. J Cell Sci. 2002;114(Pt 23):4143–51. PMID: 11739647.
    • (2002) J Cell Sci , vol.114 , pp. 4143-4151
    • Berditchevski, F.1
  • 23
    • 0036902646 scopus 로고    scopus 로고
    • Receptor downregulation and multivesicular-body sorting
    • PID: 12461556, COI: 1:CAS:528:DC%2BD38XptFKnt7s%3D, PMID: 12461556
    • Katzmann DJ, Odorizzi G, Emr SD. Receptor downregulation and multivesicular-body sorting. Nat Rev Mol Cell Biol. 2002;3(12):893–905. PMID: 12461556.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , Issue.12 , pp. 893-905
    • Katzmann, D.J.1    Odorizzi, G.2    Emr, S.D.3
  • 24
    • 84863206297 scopus 로고    scopus 로고
    • Syndecan-syntenin-ALIX regulates the biogenesis of exosomes
    • PID: 22660413, COI: 1:CAS:528:DC%2BC38XnvVyqtr0%3D, PMID: 22660413
    • Baietti MF, Zhang Z, Mortier E, Melchior A, Degeest G, Geeraerts A, et al. Syndecan-syntenin-ALIX regulates the biogenesis of exosomes. Nat Cell Biol. 2012;14(7):677–85. PMID: 22660413.
    • (2012) Nat Cell Biol , vol.14 , Issue.7 , pp. 677-685
    • Baietti, M.F.1    Zhang, Z.2    Mortier, E.3    Melchior, A.4    Degeest, G.5    Geeraerts, A.6
  • 25
    • 70349316341 scopus 로고    scopus 로고
    • Proteomic and immunologic analyses of brain tumor exosomes
    • PID: 19109410, COI: 1:CAS:528:DC%2BD1MXlsFSms7c%3D, PMID: 19109410
    • Graner MW, Alzate O, Dechkovskaia AM, Keene JD, Sampson JH, Mitchell DA, et al. Proteomic and immunologic analyses of brain tumor exosomes. FASEB J. 2009;23(5):1541–57. PMID: 19109410.
    • (2009) FASEB J , vol.23 , Issue.5 , pp. 1541-1557
    • Graner, M.W.1    Alzate, O.2    Dechkovskaia, A.M.3    Keene, J.D.4    Sampson, J.H.5    Mitchell, D.A.6
  • 26
    • 84864399889 scopus 로고    scopus 로고
    • Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles
    • PID: 22848702, COI: 1:CAS:528:DC%2BC38XhtFCgur%2FP, PMID: 22848702
    • Epple LM, Griffiths SG, Dechkovskaia AM, Dusto NL, White J, Ouellette RJ, et al. Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles. PLoS ONE. 2012;7(7):e42064. PMID: 22848702.
    • (2012) PLoS ONE , vol.7 , Issue.7 , pp. e42064
    • Epple, L.M.1    Griffiths, S.G.2    Dechkovskaia, A.M.3    Dusto, N.L.4    White, J.5    Ouellette, R.J.6
  • 27
    • 84894578152 scopus 로고    scopus 로고
    • Glioblastoma extracellular vesicles: reservoirs of potential biomarkers
    • PID: 24634586, PMID: 24634586
    • Redzic JS, Ung TH, Graner MW. Glioblastoma extracellular vesicles: reservoirs of potential biomarkers. Pharmgenomics Pers Med. 2014;7:65–77. PMID: 24634586.
    • (2014) Pharmgenomics Pers Med , vol.7 , pp. 65-77
    • Redzic, J.S.1    Ung, T.H.2    Graner, M.W.3
  • 28
    • 84886089551 scopus 로고    scopus 로고
    • The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered
    • PID: 23777544, COI: 1:CAS:528:DC%2BC3sXhs1WnsrrM, PMID: 23777544
    • Gan HK, Cvrljevic AN, Johns TG. The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered. FEBS J. 2013;280(21):5350–70. PMID: 23777544.
    • (2013) FEBS J , vol.280 , Issue.21 , pp. 5350-5370
    • Gan, H.K.1    Cvrljevic, A.N.2    Johns, T.G.3
  • 29
    • 27744484054 scopus 로고    scopus 로고
    • The natural history of EGFR and EGFRvIII in glioblastoma patients
    • PID: 16236164, PMID: 16236164
    • Heimberger AB, Suki D, Yang D, Shi W, Aldape K. The natural history of EGFR and EGFRvIII in glioblastoma patients. J Transl Med. 2005;3:38. PMID: 16236164.
    • (2005) J Transl Med , vol.3 , pp. 38
    • Heimberger, A.B.1    Suki, D.2    Yang, D.3    Shi, W.4    Aldape, K.5
  • 30
    • 84876927914 scopus 로고    scopus 로고
    • Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
    • PID: 23589885, COI: 1:CAS:528:DC%2BC3sXos1Oitrc%3D, PMID: 23589885
    • Kucharzewska P, Christianson HC, Welch JE, Svensson KJ, Fredlund E, Ringnér M, et al. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc Natl Acad Sci USA. 2013;110:7312–7. PMID: 23589885.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 7312-7317
    • Kucharzewska, P.1    Christianson, H.C.2    Welch, J.E.3    Svensson, K.J.4    Fredlund, E.5    Ringnér, M.6
  • 31
    • 79551608032 scopus 로고    scopus 로고
    • Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences
    • PID: 21285958, PMID: 21285958
    • Balaj L, Lessard R, Dai L, Pomeroy SL, Breakefield XO, Skog J. Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences. Nat Commun. 2011;2:180. PMID: 21285958.
    • (2011) Nat Commun , vol.2 , pp. 180
    • Balaj, L.1    Lessard, R.2    Dai, L.3    Pomeroy, S.L.4    Breakefield, X.O.5    Skog, J.6
  • 32
    • 57049103401 scopus 로고    scopus 로고
    • Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
    • PID: 19011622, COI: 1:CAS:528:DC%2BD1cXhsVentbfI, PMID: 19011622
    • Skog J, Würdinger T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol. 2008;10(12):1470–6. PMID: 19011622.
    • (2008) Nat Cell Biol , vol.10 , Issue.12 , pp. 1470-1476
    • Skog, J.1    Würdinger, T.2    van Rijn, S.3    Meijer, D.H.4    Gainche, L.5    Sena-Esteves, M.6
  • 33
    • 84855784507 scopus 로고    scopus 로고
    • RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls
    • PID: 22251860, COI: 1:CAS:528:DC%2BC38Xlsl2rsL4%3D, PMID: 22251860
    • Noerholm M, Balaj L, Limperg T, Salehi A, Zhu LD, Hochberg FH, et al. RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls. BMC Cancer. 2012;12:22. PMID: 22251860.
    • (2012) BMC Cancer , vol.12 , pp. 22
    • Noerholm, M.1    Balaj, L.2    Limperg, T.3    Salehi, A.4    Zhu, L.D.5    Hochberg, F.H.6
  • 34
    • 80053356340 scopus 로고    scopus 로고
    • Blood platelets contain tumor-derived RNA biomarkers
    • PMID: 21832279
    • Nilsson RJ, Balaj L, Hulleman E, van Rijn S, Pegtel DM, Walraven M, et al. Blood platelets contain tumor-derived RNA biomarkers. Blood. 2009;118(13):3680–3. PMID: 21832279.
    • (2009) Blood , vol.118 , Issue.13 , pp. 3680-3683
    • Nilsson, R.J.1    Balaj, L.2    Hulleman, E.3    van Rijn, S.4    Pegtel, D.M.5    Walraven, M.6
  • 35
    • 84883111834 scopus 로고    scopus 로고
    • Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells
    • PID: 23807490, COI: 1:CAS:528:DC%2BC2cXpslGgsA%3D%3D, PMID: 23807490
    • Li CC, Eaton SA, Young PE, Lee M, Shuttleworth R, Humphreys DT, et al. Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells. RNA Biol. 2013;10(8):1333–44. PMID: 23807490.
    • (2013) RNA Biol , vol.10 , Issue.8 , pp. 1333-1344
    • Li, C.C.1    Eaton, S.A.2    Young, P.E.3    Lee, M.4    Shuttleworth, R.5    Humphreys, D.T.6
  • 36
    • 78649717382 scopus 로고    scopus 로고
    • Aberrant methylation and associated transcriptional mobilization of Alu elements contributes to genomic instability in hypoxia
    • PID: 19508390, COI: 1:CAS:528:DC%2BC3MXjslKlsA%3D%3D, PMID: 19508390
    • Pal A, Srivastava T, Sharma MK, Mehndiratta M, Das P, Sinha S, et al. Aberrant methylation and associated transcriptional mobilization of Alu elements contributes to genomic instability in hypoxia. J Cell Mol Med. 2010;14(11):2646–54. PMID: 19508390.
    • (2010) J Cell Mol Med , vol.14 , Issue.11 , pp. 2646-2654
    • Pal, A.1    Srivastava, T.2    Sharma, M.K.3    Mehndiratta, M.4    Das, P.5    Sinha, S.6
  • 37
    • 77649259296 scopus 로고    scopus 로고
    • MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells
    • COI: 1:CAS:528:DC%2BC3cXlt1KrsL4%3D, PMID: 20227367
    • Godlewski J, Nowicki MO, Bronisz A, Nuovo G, Palatini J, De Lay M, et al. MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells. Mol Cell. 2010;37:620–32. PMID: 20227367.
    • (2010) Mol Cell , vol.37 , pp. 620-632
    • Godlewski, J.1    Nowicki, M.O.2    Bronisz, A.3    Nuovo, G.4    Palatini, J.5    De Lay, M.6
  • 38
    • 58649087374 scopus 로고    scopus 로고
    • miR-21: a small multi-faceted RNA
    • PID: 19175699, COI: 1:CAS:528:DC%2BD1MXjsVegurY%3D, PMID: 19175699
    • Krichevsky AM, Gabriely G. miR-21: a small multi-faceted RNA. J Cell Mol Med. 2009;13(1):39–53. PMID: 19175699.
    • (2009) J Cell Mol Med , vol.13 , Issue.1 , pp. 39-53
    • Krichevsky, A.M.1    Gabriely, G.2
  • 39
    • 84886938691 scopus 로고    scopus 로고
    • MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development
    • PID: 24205116, COI: 1:CAS:528:DC%2BC3sXhs12js7zJ, PMID: 24205116
    • Akers JC, Ramakrishnan V, Kim R, Skog J, Nakano I, Pingle S, et al. MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development. PLoS ONE. 2013;8(10):e78115. PMID: 24205116.
    • (2013) PLoS ONE , vol.8 , Issue.10 , pp. e78115
    • Akers, J.C.1    Ramakrishnan, V.2    Kim, R.3    Skog, J.4    Nakano, I.5    Pingle, S.6
  • 40
    • 42149132635 scopus 로고    scopus 로고
    • Chemoresistance in gliomas
    • PID: 18259841, COI: 1:CAS:528:DC%2BD1cXkvVOhsbs%3D, PMID: 18259841
    • Lu C, Shervington A. Chemoresistance in gliomas. Mol Cell Biochem. 2008;312(1–2):71–80. PMID: 18259841.
    • (2008) Mol Cell Biochem , vol.312 , Issue.1-2 , pp. 71-80
    • Lu, C.1    Shervington, A.2
  • 41
    • 70349652191 scopus 로고    scopus 로고
    • The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs
    • PID: 19749744, COI: 1:CAS:528:DC%2BD1MXht1SqsLnI, PMID: 19749744
    • Persson H, Kvist A, Vallon-Christersson J, Medstrand P, Borg A, Rovira C. The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs. Nat Cell Biol. 2009;11(10):1268–71. PMID: 19749744.
    • (2009) Nat Cell Biol , vol.11 , Issue.10 , pp. 1268-1271
    • Persson, H.1    Kvist, A.2    Vallon-Christersson, J.3    Medstrand, P.4    Borg, A.5    Rovira, C.6
  • 42
    • 84886387008 scopus 로고    scopus 로고
    • Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity
    • PID: 24101524, COI: 1:CAS:528:DC%2BC3sXhslejsLjJ, PMID: 24101524
    • Christianson HC, Svensson KJ, van Kuppevelt TH, Li JP, Belting M. Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity. Proc Natl Acad Sci USA. 2013;110(43):17380–5. PMID: 24101524.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.43 , pp. 17380-17385
    • Christianson, H.C.1    Svensson, K.J.2    van Kuppevelt, T.H.3    Li, J.P.4    Belting, M.5
  • 43
    • 84877691199 scopus 로고    scopus 로고
    • Proteoglycans and their roles in brain cancer
    • PID: 23281850, COI: 1:CAS:528:DC%2BC3sXnt12rur4%3D, PMID: 23281850
    • Wade A, Robinson AE, Engler JR, Petritsch C, James CD, Phillips JJ. Proteoglycans and their roles in brain cancer. FEBS J. 2013;280(10):2399–417. PMID: 23281850.
    • (2013) FEBS J , vol.280 , Issue.10 , pp. 2399-2417
    • Wade, A.1    Robinson, A.E.2    Engler, J.R.3    Petritsch, C.4    James, C.D.5    Phillips, J.J.6
  • 44
    • 84879046970 scopus 로고    scopus 로고
    • Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid raft-mediated endocytosis negatively regulated by caveolin-1
    • PID: 23653359, COI: 1:CAS:528:DC%2BC3sXpsFagtro%3D, PMID: 23653359
    • Svensson KJ, Christianson HC, Wittrup A, Bourseau-Guilmain E, Lindqvist E, Svensson LM, et al. Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid raft-mediated endocytosis negatively regulated by caveolin-1. J Biol Chem. 2013;288(24):17713–24. PMID: 23653359.
    • (2013) J Biol Chem , vol.288 , Issue.24 , pp. 17713-17724
    • Svensson, K.J.1    Christianson, H.C.2    Wittrup, A.3    Bourseau-Guilmain, E.4    Lindqvist, E.5    Svensson, L.M.6
  • 45
    • 84890312241 scopus 로고    scopus 로고
    • Heparin blocks transfer of extracellular vesicles between donor and recipient cells
    • PID: 24002181, COI: 1:CAS:528:DC%2BC3sXhtl2isrjI, PMID: 24002181
    • Atai NA, Balaj L, van Veen H, Breakefield XO, Jarzyna PA, Van Noorden CJ, et al. Heparin blocks transfer of extracellular vesicles between donor and recipient cells. J Neurooncol. 2013;115(3):343–51. PMID: 24002181.
    • (2013) J Neurooncol , vol.115 , Issue.3 , pp. 343-351
    • Atai, N.A.1    Balaj, L.2    van Veen, H.3    Breakefield, X.O.4    Jarzyna, P.A.5    Van Noorden, C.J.6
  • 46
    • 84896491146 scopus 로고    scopus 로고
    • Tumor exosomes induce tunneling nanotubes in lipid raft-enriched regions of human mesothelioma cells
    • PMID: 24468420
    • Thayanithy V, Babatunde V, Dickson EL, Wong P, Oh S, Ke X, et al. Tumor exosomes induce tunneling nanotubes in lipid raft-enriched regions of human mesothelioma cells. Exp Cell Res. 2014;323(1):1781–8. PMID: 24468420.
    • (2014) Exp Cell Res , vol.323 , Issue.1 , pp. 1781-1788
    • Thayanithy, V.1    Babatunde, V.2    Dickson, E.L.3    Wong, P.4    Oh, S.5    Ke, X.6
  • 47
    • 44349098785 scopus 로고    scopus 로고
    • Membrane nanotubes: dynamic long-distance connections between animal cells
    • PID: 18431401, COI: 1:CAS:528:DC%2BD1cXmt1OlsLs%3D, PMID: 18431401
    • Davis DM, Sowinski S. Membrane nanotubes: dynamic long-distance connections between animal cells. Nat Rev Mol Cell Biol. 2008;9(6):431–6. PMID: 18431401.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.6 , pp. 431-436
    • Davis, D.M.1    Sowinski, S.2
  • 48
    • 34250325547 scopus 로고    scopus 로고
    • Higher-order oligomerization targets plasma membrane proteins and HIV gag to exosomes
    • PID: 17550307, PMID: 17550307
    • Fang Y, Wu N, Gan X, Yan W, Morrell JC, Gould SJ. Higher-order oligomerization targets plasma membrane proteins and HIV gag to exosomes. PLoS Biol. 2007;5(6):e158. PMID: 17550307.
    • (2007) PLoS Biol , vol.5 , Issue.6 , pp. e158
    • Fang, Y.1    Wu, N.2    Gan, X.3    Yan, W.4    Morrell, J.C.5    Gould, S.J.6
  • 49
    • 84896910344 scopus 로고    scopus 로고
    • Emerging technologies in extracellular vesicle-based molecular diagnostics
    • PID: 24575799, COI: 1:CAS:528:DC%2BC2cXks1GmtL8%3D, PMID: 24575799
    • Jia S, Zocco D, Samuels ML, Chou MF, Chammas R, Skog J, et al. Emerging technologies in extracellular vesicle-based molecular diagnostics. Expert Rev Mol Diagn. 2014;14(3):307–21. PMID: 24575799.
    • (2014) Expert Rev Mol Diagn , vol.14 , Issue.3 , pp. 307-321
    • Jia, S.1    Zocco, D.2    Samuels, M.L.3    Chou, M.F.4    Chammas, R.5    Skog, J.6
  • 50
    • 34250877865 scopus 로고    scopus 로고
    • Genetic pathways to primary and secondary glioblastoma
    • PID: 17456751, COI: 1:CAS:528:DC%2BD2sXlvFCns74%3D, PMID: 17456751
    • Ohgaki H, Kleihues P. Genetic pathways to primary and secondary glioblastoma. Am J Pathol. 2007;170(5):1445–53. PMID: 17456751.
    • (2007) Am J Pathol , vol.170 , Issue.5 , pp. 1445-1453
    • Ohgaki, H.1    Kleihues, P.2
  • 51
    • 84891551331 scopus 로고    scopus 로고
    • Current understanding on EGFR and Wnt/β-catenin signaling in glioma and their possible crosstalk
    • COI: 1:CAS:528:DC%2BC2cXhsVGktbbO, PMID: 24386505
    • Paul I, Bhattacharya S, Chatterjee A, Ghosh MK. Current understanding on EGFR and Wnt/β-catenin signaling in glioma and their possible crosstalk. Genes Cancer. 2013;4(11–12):427–46. PMID: 24386505.
    • (2013) Genes Cancer , vol.4 , Issue.11-12 , pp. 427-446
    • Paul, I.1    Bhattacharya, S.2    Chatterjee, A.3    Ghosh, M.K.4
  • 52
    • 0034163550 scopus 로고    scopus 로고
    • Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas
    • PID: 10728703, COI: 1:CAS:528:DC%2BD3cXhvFWrtLw%3D, PMID: 10728703
    • Frederick L, Wang XY, Eley G, James CD. Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas. Cancer Res. 2000;60(5):1383–7. PMID: 10728703.
    • (2000) Cancer Res , vol.60 , Issue.5 , pp. 1383-1387
    • Frederick, L.1    Wang, X.Y.2    Eley, G.3    James, C.D.4
  • 53
    • 0026772431 scopus 로고
    • Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops
    • PID: 1317261, COI: 1:CAS:528:DyaK38Xkt1Cjsbw%3D, PMID: 1317261
    • Hermanson M, Funa K, Hartman M, Claesson-Welsh L, Heldin CH, Westermark B, et al. Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. Cancer Res. 1992;52(11):3213–9. PMID: 1317261.
    • (1992) Cancer Res , vol.52 , Issue.11 , pp. 3213-3219
    • Hermanson, M.1    Funa, K.2    Hartman, M.3    Claesson-Welsh, L.4    Heldin, C.H.5    Westermark, B.6
  • 55
    • 31644442040 scopus 로고    scopus 로고
    • Platelet-derived growth factor (PDGF) and glial tumorigenesis
    • PID: 16139423, COI: 1:CAS:528:DC%2BD28XhtFWhurk%3D, PMID: 16139423
    • Shih AH, Holland EC. Platelet-derived growth factor (PDGF) and glial tumorigenesis. Cancer Lett. 2006;232(2):139–47. PMID: 16139423.
    • (2006) Cancer Lett , vol.232 , Issue.2 , pp. 139-147
    • Shih, A.H.1    Holland, E.C.2
  • 56
    • 34547871259 scopus 로고    scopus 로고
    • Targeting HER proteins in cancer therapy and the role of the non-target HER3
    • PID: 17667926, COI: 1:CAS:528:DC%2BD2sXptVWju7g%3D, PMID: 17667926
    • Hsieh AC, Moasser MM. Targeting HER proteins in cancer therapy and the role of the non-target HER3. Br J Cancer. 2007;97(4):453–7. PMID: 17667926.
    • (2007) Br J Cancer , vol.97 , Issue.4 , pp. 453-457
    • Hsieh, A.C.1    Moasser, M.M.2
  • 57
    • 34547854801 scopus 로고    scopus 로고
    • The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis
    • PID: 17471238, COI: 1:CAS:528:DC%2BD2sXhtFagsbnN, PMID: 17471238
    • Moasser MM. The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis. Oncogene. 2007;26(45):6469–87. PMID: 17471238.
    • (2007) Oncogene , vol.26 , Issue.45 , pp. 6469-6487
    • Moasser, M.M.1
  • 58
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • PID: 16024602, COI: 1:CAS:528:DC%2BD2MXmt1eht7c%3D, PMID: 16024602
    • Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 2005;65(14):6029–33. PMID: 16024602.
    • (2005) Cancer Res , vol.65 , Issue.14 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 59
    • 55949114921 scopus 로고    scopus 로고
    • MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G
    • PID: 19013014, COI: 1:CAS:528:DC%2BD1cXhtlyhtr%2FL, PMID: 19013014
    • Chen Y, Liu W, Chao T, Zhang Y, Yan X, Gong Y, et al. MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G. Cancer Lett. 2008;272:197–205. PMID: 19013014.
    • (2008) Cancer Lett , vol.272 , pp. 197-205
    • Chen, Y.1    Liu, W.2    Chao, T.3    Zhang, Y.4    Yan, X.5    Gong, Y.6
  • 60
    • 54249136806 scopus 로고    scopus 로고
    • MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
    • PID: 18829576, COI: 1:CAS:528:DC%2BD1cXhtF2msLjO, PMID: 18829576
    • Papagiannakopoulos T, Shapiro A, Kosik KS. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res. 2008;68(19):8164–72. PMID: 18829576.
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 8164-8172
    • Papagiannakopoulos, T.1    Shapiro, A.2    Kosik, K.S.3
  • 61
    • 79959315095 scopus 로고    scopus 로고
    • Apoptosis and the target genes of microRNA-21
    • PID: 21627859, PMID: 21627859
    • Buscaglia LE, Li Y. Apoptosis and the target genes of microRNA-21. Chin J Cancer. 2011;30(6):371–80. PMID: 21627859.
    • (2011) Chin J Cancer , vol.30 , Issue.6 , pp. 371-380
    • Buscaglia, L.E.1    Li, Y.2
  • 62
    • 84873139483 scopus 로고    scopus 로고
    • Angiogenesis and hypoxia in glioblastoma: a focus on cancer stem cells
    • PID: 23131159, COI: 1:CAS:528:DC%2BC3sXhslGis7g%3D, PMID: 23131159
    • Mongiardi MP. Angiogenesis and hypoxia in glioblastoma: a focus on cancer stem cells. CNS Neurol Disord Drug Targets. 2012;11(7):878–83. PMID: 23131159.
    • (2012) CNS Neurol Disord Drug Targets , vol.11 , Issue.7 , pp. 878-883
    • Mongiardi, M.P.1
  • 63
    • 84890943320 scopus 로고    scopus 로고
    • Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth
    • PID: 24356439, PMID: 24356439
    • Verginelli F, Perin A, Dali R, Fung KH, Lo R, Longatti P, et al. Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth. Nat Commun. 2013;4:2956. PMID: 24356439.
    • (2013) Nat Commun , vol.4 , pp. 2956
    • Verginelli, F.1    Perin, A.2    Dali, R.3    Fung, K.H.4    Lo, R.5    Longatti, P.6
  • 64
    • 0345688213 scopus 로고    scopus 로고
    • Vaults: a ribonucleoprotein particle involved in drug resistance?
    • PID: 14576851, COI: 1:CAS:528:DC%2BD3sXotlaju7w%3D, PMID: 14576851
    • Mossink MH, van Zon A, Scheper RJ, Sonneveld P, Wiemer EA. Vaults: a ribonucleoprotein particle involved in drug resistance? Oncogene. 2003;22(47):7458–67. PMID: 14576851.
    • (2003) Oncogene , vol.22 , Issue.47 , pp. 7458-7467
    • Mossink, M.H.1    van Zon, A.2    Scheper, R.J.3    Sonneveld, P.4    Wiemer, E.A.5
  • 65
    • 79955580832 scopus 로고    scopus 로고
    • Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes
    • PID: 21119685, COI: 1:CAS:528:DC%2BC3MXlsVGjt78%3D, PMID: 21119685
    • Nie L, Zhao Y, Wu W, Yang YZ, Wang HC, Sun XH, et al. Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes. Cell Res. 2011;21(5):754–69. PMID: 21119685.
    • (2011) Cell Res , vol.21 , Issue.5 , pp. 754-769
    • Nie, L.1    Zhao, Y.2    Wu, W.3    Yang, Y.Z.4    Wang, H.C.5    Sun, X.H.6
  • 66
    • 67650087998 scopus 로고    scopus 로고
    • Combined targeting of interleukin-6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness
    • PID: 19431143, COI: 1:CAS:528:DC%2BD1MXovVersrY%3D, PMID: 19431143
    • Saidi A, Hagedorn M, Allain N, Verpelli C, Sala C, Bello L, et al. Combined targeting of interleukin-6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness. Int J Cancer. 2009;125(5):1054–64. PMID: 19431143.
    • (2009) Int J Cancer , vol.125 , Issue.5 , pp. 1054-1064
    • Saidi, A.1    Hagedorn, M.2    Allain, N.3    Verpelli, C.4    Sala, C.5    Bello, L.6
  • 67
    • 67349149657 scopus 로고    scopus 로고
    • Analysis of interleukin (IL)-8 expression in human astrocytomas: associations with IL-6, cyclooxygenase-2, vascular endothelial growth factor, and microvessel morphometry
    • PID: 19332096, COI: 1:CAS:528:DC%2BD1MXmsFyitbY%3D, PMID: 19332096
    • Samaras V, Piperi C, Levidou G, Zisakis A, Kavantzas N, Themistocleous MS, et al. Analysis of interleukin (IL)-8 expression in human astrocytomas: associations with IL-6, cyclooxygenase-2, vascular endothelial growth factor, and microvessel morphometry. Hum Immunol. 2009;70(6):391–7. PMID: 19332096.
    • (2009) Hum Immunol , vol.70 , Issue.6 , pp. 391-397
    • Samaras, V.1    Piperi, C.2    Levidou, G.3    Zisakis, A.4    Kavantzas, N.5    Themistocleous, M.S.6
  • 68
    • 79951515139 scopus 로고    scopus 로고
    • Antiglioma effects of a new, low molecular mass, inhibitor of fibroblast growth factor
    • PID: 21193016, COI: 1:CAS:528:DC%2BC3MXhvFenu7k%3D, PMID: 21193016
    • Cuevas P, Carceller F, Angulo J, González-Corrochano R, Cuevas-Bourdier A, Giménez-Gallego G, et al. Antiglioma effects of a new, low molecular mass, inhibitor of fibroblast growth factor. Neurosci Lett. 2011;491(1):1–7. PMID: 21193016.
    • (2011) Neurosci Lett , vol.491 , Issue.1 , pp. 1-7
    • Cuevas, P.1    Carceller, F.2    Angulo, J.3    González-Corrochano, R.4    Cuevas-Bourdier, A.5    Giménez-Gallego, G.6
  • 69
    • 84855461449 scopus 로고    scopus 로고
    • MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop
    • PID: 22156201, COI: 1:CAS:528:DC%2BC38XkvFCmtw%3D%3D, PMID: 22156201
    • Jiang L, Lin C, Song L, Wu J, Chen B, Ying Z, et al. MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop. J Clin Invest. 2012;122(1):33–47. PMID: 22156201.
    • (2012) J Clin Invest , vol.122 , Issue.1 , pp. 33-47
    • Jiang, L.1    Lin, C.2    Song, L.3    Wu, J.4    Chen, B.5    Ying, Z.6
  • 70
    • 84876246021 scopus 로고    scopus 로고
    • Transforming growth factor β-regulated microRNA-29a promotes angiogenesis through targeting the phosphatase and tensin homolog in endothelium
    • PMID: 23426367
    • Wang J, Wang Y, Wang Y, Ma Y, Lan Y, Yang X, et al. Transforming growth factor β-regulated microRNA-29a promotes angiogenesis through targeting the phosphatase and tensin homolog in endothelium. J Biol Chem. 2012;288(15):10418–26. PMID: 23426367.
    • (2012) J Biol Chem , vol.288 , Issue.15 , pp. 10418-10426
    • Wang, J.1    Wang, Y.2    Wang, Y.3    Ma, Y.4    Lan, Y.5    Yang, X.6
  • 71
    • 84868201567 scopus 로고    scopus 로고
    • Identification of seven serum microRNAs from a genome-wide serum microRNA expression profile as potential noninvasive biomarkers for malignant astrocytomas
    • PID: 22674182, COI: 1:CAS:528:DC%2BC38XptVyis7s%3D, PMID: 22674182
    • Yang C, Wang C, Chen X, Chen S, Zhang Y, Zhi F, et al. Identification of seven serum microRNAs from a genome-wide serum microRNA expression profile as potential noninvasive biomarkers for malignant astrocytomas. Int J Cancer. 2013;132(1):116–27. PMID: 22674182.
    • (2013) Int J Cancer , vol.132 , Issue.1 , pp. 116-127
    • Yang, C.1    Wang, C.2    Chen, X.3    Chen, S.4    Zhang, Y.5    Zhi, F.6
  • 73
    • 84891671335 scopus 로고    scopus 로고
    • Ionizing radiation and glioblastoma exosomes: implications in tumor biology and cell migration
    • PID: 24466366, PMID: 24466366
    • Arscott WT, Tandle AT, Zhao S, Shabason JE, Gordon IK, Schlaff CD, et al. Ionizing radiation and glioblastoma exosomes: implications in tumor biology and cell migration. Transl Oncol. 2013;6(6):638–48. PMID: 24466366.
    • (2013) Transl Oncol , vol.6 , Issue.6 , pp. 638-648
    • Arscott, W.T.1    Tandle, A.T.2    Zhao, S.3    Shabason, J.E.4    Gordon, I.K.5    Schlaff, C.D.6
  • 74
    • 84867245365 scopus 로고    scopus 로고
    • L1CAM: a major driver for tumor cell invasion and motility
    • PMID: 22796939
    • Kiefel H, Bondong S, Hazin J, Ridinger J, Schirmer U, Riedle S, et al. L1CAM: a major driver for tumor cell invasion and motility. Cell Adh Migr. 2012;6(4):374–84. PMID: 22796939.
    • (2012) Cell Adh Migr , vol.6 , Issue.4 , pp. 374-384
    • Kiefel, H.1    Bondong, S.2    Hazin, J.3    Ridinger, J.4    Schirmer, U.5    Riedle, S.6
  • 75
    • 70749095750 scopus 로고    scopus 로고
    • Stimulation of glioma cell motility by expression, proteolysis, and release of the L1 neural cell recognition molecule
    • PID: 19874583, PMID: 19874583
    • Yang M, Adla S, Temburni MK, Patel VP, Lagow EL, Brady OA, et al. Stimulation of glioma cell motility by expression, proteolysis, and release of the L1 neural cell recognition molecule. Cancer Cell Int. 2009;9:27. PMID: 19874583.
    • (2009) Cancer Cell Int , vol.9 , pp. 27
    • Yang, M.1    Adla, S.2    Temburni, M.K.3    Patel, V.P.4    Lagow, E.L.5    Brady, O.A.6
  • 76
    • 82955169603 scopus 로고    scopus 로고
    • L1 stimulation of human glioma cell motility correlates with FAK activation
    • PID: 21373966, COI: 1:CAS:528:DC%2BC3MXhtF2js7bF, PMID: 21373966
    • Yang M, Li Y, Chilukuri K, Brady OA, Boulos MI, Kappes JC, et al. L1 stimulation of human glioma cell motility correlates with FAK activation. J Neurooncol. 2011;105(1):27–44. PMID: 21373966.
    • (2011) J Neurooncol , vol.105 , Issue.1 , pp. 27-44
    • Yang, M.1    Li, Y.2    Chilukuri, K.3    Brady, O.A.4    Boulos, M.I.5    Kappes, J.C.6
  • 77
    • 47549089465 scopus 로고    scopus 로고
    • The RGD integrin binding site in human L1-CAM is important for nuclear signaling
    • PID: 18555990, COI: 1:CAS:528:DC%2BD1cXptVekuro%3D, PMID: 18555990
    • Gast D, Riedle S, Kiefel H, Müerköster SS, Schäfer H, Schäfer MK, et al. The RGD integrin binding site in human L1-CAM is important for nuclear signaling. Exp Cell Res. 2008;314(13):2411–8. PMID: 18555990.
    • (2008) Exp Cell Res , vol.314 , Issue.13 , pp. 2411-2418
    • Gast, D.1    Riedle, S.2    Kiefel, H.3    Müerköster, S.S.4    Schäfer, H.5    Schäfer, M.K.6
  • 78
    • 84876494831 scopus 로고    scopus 로고
    • L1CAM stimulates glioma cell motility and proliferation through the fibroblast growth factor receptor
    • PID: 23212305, COI: 1:CAS:528:DC%2BC3sXlsFWqs78%3D, PMID: 23212305
    • Mohanan V, Temburni MK, Kappes JC, Galileo DS. L1CAM stimulates glioma cell motility and proliferation through the fibroblast growth factor receptor. Clin Exp Metastasis. 2013;30(4):507–20. PMID: 23212305.
    • (2013) Clin Exp Metastasis , vol.30 , Issue.4 , pp. 507-520
    • Mohanan, V.1    Temburni, M.K.2    Kappes, J.C.3    Galileo, D.S.4
  • 79
    • 84867273359 scopus 로고    scopus 로고
    • EMT-associated up-regulation of L1CAM provides insights into L1CAM-mediated integrin signalling and NF-κB activation
    • PID: 22764136, COI: 1:CAS:528:DC%2BC38XhsVOhs7vF, PMID: 22764136
    • Kiefel H, Bondong S, Pfeifer M, Schirmer U, Erbe-Hoffmann N, Schäfer H, et al. EMT-associated up-regulation of L1CAM provides insights into L1CAM-mediated integrin signalling and NF-κB activation. Carcinogenesis. 2012;33(10):1919–29. PMID: 22764136.
    • (2012) Carcinogenesis , vol.33 , Issue.10 , pp. 1919-1929
    • Kiefel, H.1    Bondong, S.2    Pfeifer, M.3    Schirmer, U.4    Erbe-Hoffmann, N.5    Schäfer, H.6
  • 80
    • 80051971645 scopus 로고    scopus 로고
    • Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells
    • PID: 21788507, COI: 1:CAS:528:DC%2BC3MXhtVKit7fP, PMID: 21788507
    • Svensson KJ, Kucharzewska P, Christianson HC, Sköld S, Löfstedt T, Johansson MC, et al. Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells. Proc Natl Acad Sci USA. 2011;108(32):13147–52. PMID: 21788507.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.32 , pp. 13147-13152
    • Svensson, K.J.1    Kucharzewska, P.2    Christianson, H.C.3    Sköld, S.4    Löfstedt, T.5    Johansson, M.C.6
  • 81
    • 0043092322 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes
    • PID: 12907597, COI: 1:CAS:528:DC%2BD3sXmtFekur0%3D, PMID: 12907597
    • Wang H, Shen W, Huang H, Huang H, Hu L, Ramdas L, et al. Insulin-like growth factor binding protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes. Cancer Res. 2003;63(15):4315–21. PMID: 12907597.
    • (2003) Cancer Res , vol.63 , Issue.15 , pp. 4315-4321
    • Wang, H.1    Shen, W.2    Huang, H.3    Huang, H.4    Hu, L.5    Ramdas, L.6
  • 82
    • 77955475753 scopus 로고    scopus 로고
    • IGFBP2 promotes glioma tumor stem cell expansion and survival
    • PID: 20515648, COI: 1:CAS:528:DC%2BC3cXotVCgs7c%3D, PMID: 20515648
    • Hsieh D, Hsieh A, Stea B, Ellsworth R. IGFBP2 promotes glioma tumor stem cell expansion and survival. Biochem Biophys Res Commun. 2010;397(2):367–72. PMID: 20515648.
    • (2010) Biochem Biophys Res Commun , vol.397 , Issue.2 , pp. 367-372
    • Hsieh, D.1    Hsieh, A.2    Stea, B.3    Ellsworth, R.4
  • 83
    • 59649107705 scopus 로고    scopus 로고
    • Functions and mechanisms of action of CCN matricellular proteins
    • PID: 18775791, COI: 1:CAS:528:DC%2BD1MXitFSmtL0%3D, PMID: 18775791
    • Chen CC, Lau LF. Functions and mechanisms of action of CCN matricellular proteins. Int J Biochem Cell Biol. 2009;41(4):771–83. PMID: 18775791.
    • (2009) Int J Biochem Cell Biol , vol.41 , Issue.4 , pp. 771-783
    • Chen, C.C.1    Lau, L.F.2
  • 84
    • 79961245372 scopus 로고    scopus 로고
    • Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion
    • PID: 21771732, COI: 1:CAS:528:DC%2BC3MXhtVSitbfE, PMID: 21771732
    • Edwards LA, Woolard K, Son MJ, Li A, Lee J, Ene C, et al. Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion. J Natl Cancer Inst. 2011;103(15):1162–78. PMID: 21771732.
    • (2011) J Natl Cancer Inst , vol.103 , Issue.15 , pp. 1162-1178
    • Edwards, L.A.1    Woolard, K.2    Son, M.J.3    Li, A.4    Lee, J.5    Ene, C.6
  • 85
    • 0035193041 scopus 로고    scopus 로고
    • Nerve growth factor stimulates multisite tyrosine phosphorylation and activation of the atypical protein kinase C’s via a src kinase pathway
    • PID: 11713277, COI: 1:CAS:528:DC%2BD3MXovVegsLc%3D, PMID: 11713277
    • Wooten MW, Vandenplas ML, Seibenhener ML, Geetha T, Diaz-Meco MT. Nerve growth factor stimulates multisite tyrosine phosphorylation and activation of the atypical protein kinase C’s via a src kinase pathway. Mol Cell Biol. 2001;21(24):8414–27. PMID: 11713277.
    • (2001) Mol Cell Biol , vol.21 , Issue.24 , pp. 8414-8427
    • Wooten, M.W.1    Vandenplas, M.L.2    Seibenhener, M.L.3    Geetha, T.4    Diaz-Meco, M.T.5
  • 86
    • 0033229747 scopus 로고    scopus 로고
    • Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase
    • PMID: 10545504
    • Renshaw MW, Price LS, Schwartz MA. Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase. J Cell Biol. 2001;147(3):611–8. PMID: 10545504.
    • (2001) J Cell Biol , vol.147 , Issue.3 , pp. 611-618
    • Renshaw, M.W.1    Price, L.S.2    Schwartz, M.A.3
  • 87
    • 0742323216 scopus 로고    scopus 로고
    • The expression of matrix metalloproteinase-2 and -9 in human gliomas of different pathological grades
    • PID: 14756443, PMID: 14756443
    • Wang M, Wang T, Liu S, Yoshida D, Teramoto A. The expression of matrix metalloproteinase-2 and -9 in human gliomas of different pathological grades. Brain Tumor Pathol. 2003;20(2):65–72. PMID: 14756443.
    • (2003) Brain Tumor Pathol , vol.20 , Issue.2 , pp. 65-72
    • Wang, M.1    Wang, T.2    Liu, S.3    Yoshida, D.4    Teramoto, A.5
  • 88
    • 3142775713 scopus 로고    scopus 로고
    • The role of matrix metalloproteinases in glioma invasion
    • PID: 12456313, COI: 1:CAS:528:DC%2BD3sXitFygtbY%3D, PMID: 12456313
    • Nakada M, Okada Y, Yamashita J. The role of matrix metalloproteinases in glioma invasion. Front Biosci. 2003;8:e261–9. PMID: 12456313.
    • (2003) Front Biosci , vol.8 , pp. e261-e269
    • Nakada, M.1    Okada, Y.2    Yamashita, J.3
  • 89
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • PID: 9616126, COI: 1:CAS:528:DyaK1cXjsFKgsro%3D, PMID: 9616126
    • Tamura M, Gu J, Matsumoto K, Aota S, Parsons R, Yamada KM, et al. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science. 1998;280(5369):1614–7. PMID: 9616126.
    • (1998) Science , vol.280 , Issue.5369 , pp. 1614-1617
    • Tamura, M.1    Gu, J.2    Matsumoto, K.3    Aota, S.4    Parsons, R.5    Yamada, K.M.6
  • 90
    • 51849130466 scopus 로고    scopus 로고
    • PTEN signaling in brain: neuropathology and tumorigenesis
    • COI: 1:CAS:528:DC%2BD1cXhtFWiur3N, PMID: 18794877
    • Endersby R, Baker SJ. PTEN signaling in brain: neuropathology and tumorigenesis. Oncogene. 2008;27(41):5416–30. PMID: 18794877.
    • (2008) Oncogene , vol.27 , Issue.41 , pp. 5416-5430
    • Endersby, R.1    Baker, S.J.2
  • 91
    • 52149096024 scopus 로고    scopus 로고
    • PTEN signaling pathways in glioblastoma
    • PID: 18836294, COI: 1:CAS:528:DC%2BD1cXhsVKms7%2FJ, PMID: 18836294
    • Koul D. PTEN signaling pathways in glioblastoma. Cancer Biol Ther. 2008;7(9):1321–5. PMID: 18836294.
    • (2008) Cancer Biol Ther , vol.7 , Issue.9 , pp. 1321-1325
    • Koul, D.1
  • 92
    • 38149124619 scopus 로고    scopus 로고
    • Membrane vesicles shed by oligodendroglioma cells induce neuronal apoptosis
    • PID: 17016637, PMID: 17016637
    • D’Agostino S, Salamone M, Di Liegro I, Vittorelli ML. Membrane vesicles shed by oligodendroglioma cells induce neuronal apoptosis. Int J Oncol. 2006;29(5):1075–85. PMID: 17016637.
    • (2006) Int J Oncol , vol.29 , Issue.5 , pp. 1075-1085
    • D’Agostino, S.1    Salamone, M.2    Di Liegro, I.3    Vittorelli, M.L.4
  • 93
    • 33745845114 scopus 로고    scopus 로고
    • Role of ABC transporters in the chemoresistance of human gliomas
    • PID: 16918310, PMID: 16918310
    • Declèves X, Amiel A, Delattre JY, Scherrmann JM. Role of ABC transporters in the chemoresistance of human gliomas. Curr Cancer Drug Targets. 2006;6(5):433–45. PMID: 16918310.
    • (2006) Curr Cancer Drug Targets , vol.6 , Issue.5 , pp. 433-445
    • Declèves, X.1    Amiel, A.2    Delattre, J.Y.3    Scherrmann, J.M.4
  • 94
    • 0042415686 scopus 로고    scopus 로고
    • Overexpression of the human major vault protein in gangliogliomas
    • COI: 1:CAS:528:DC%2BD3sXnvF2mu78%3D, PMID: 12919388
    • Aronica E, Gorter JA, van Vliet EA, Spliet WG, van Veelen CW, van Rijen PC, et al. Overexpression of the human major vault protein in gangliogliomas. Epilepsia. 2003;44(9):1166–75. PMID: 12919388.
    • (2003) Epilepsia , vol.44 , Issue.9 , pp. 1166-1175
    • Aronica, E.1    Gorter, J.A.2    van Vliet, E.A.3    Spliet, W.G.4    van Veelen, C.W.5    van Rijen, P.C.6
  • 95
    • 34147201741 scopus 로고    scopus 로고
    • Clinical significance of ABCA2 a possible molecular marker for oligodendrogliomas
    • PID: 17415208, PMID: 17415208
    • Soichi O, Masanori N, Hideo T, Kazunori A, Nobuya I, Jun-ichi K, et al. Clinical significance of ABCA2 a possible molecular marker for oligodendrogliomas. Neurosurgery. 2007;60(4):707–14. PMID: 17415208.
    • (2007) Neurosurgery , vol.60 , Issue.4 , pp. 707-714
    • Soichi, O.1    Masanori, N.2    Hideo, T.3    Kazunori, A.4    Nobuya, I.5    Jun-ichi, K.6
  • 96
    • 84871131402 scopus 로고    scopus 로고
    • Structural studies of large nucleoprotein particles, vaults
    • PID: 23060231, COI: 1:CAS:528:DC%2BC3sXhsVahtLo%3D, PMID: 23060231
    • Tanaka H, Tsukihara T. Structural studies of large nucleoprotein particles, vaults. Proc Jpn Acad Ser B Phys Biol Sci. 2012;88(8):416–33. PMID: 23060231.
    • (2012) Proc Jpn Acad Ser B Phys Biol Sci , vol.88 , Issue.8 , pp. 416-433
    • Tanaka, H.1    Tsukihara, T.2
  • 97
    • 58149502680 scopus 로고    scopus 로고
    • Vaults and the major vault protein: novel roles in signal pathway regulation and immunity
    • PID: 18759128, COI: 1:CAS:528:DC%2BD1MXktlGnsg%3D%3D, PMID: 18759128
    • Berger W, Steiner E, Grusch M, Elbling L, Micksche M. Vaults and the major vault protein: novel roles in signal pathway regulation and immunity. Cell Mol Life Sci. 2009;66(1):43–61. PMID: 18759128.
    • (2009) Cell Mol Life Sci , vol.66 , Issue.1 , pp. 43-61
    • Berger, W.1    Steiner, E.2    Grusch, M.3    Elbling, L.4    Micksche, M.5
  • 98
    • 84860836067 scopus 로고    scopus 로고
    • Contribution of microRNAs to radio- and chemoresistance of brain tumors and their therapeutic potential
    • PID: 22484336, COI: 1:CAS:528:DC%2BC38XlsFGgtrw%3D, PMID: 22484336
    • Chistiakov DA, Chekhonin VP. Contribution of microRNAs to radio- and chemoresistance of brain tumors and their therapeutic potential. Eur J Pharmacol. 2012;684(1–3):8–18. PMID: 22484336.
    • (2012) Eur J Pharmacol , vol.684 , Issue.1-3 , pp. 8-18
    • Chistiakov, D.A.1    Chekhonin, V.P.2
  • 99
    • 33747288211 scopus 로고    scopus 로고
    • Cellular functions of vaults and their involvement in multidrug resistance
    • PID: 16918321, COI: 1:CAS:528:DC%2BD28XnslClsrc%3D, PMID: 16918321
    • Steiner E, Holzmann K, Elbling L, Micksche M, Berger W. Cellular functions of vaults and their involvement in multidrug resistance. Curr Drug Targets. 2006;7(8):923–34. PMID: 16918321.
    • (2006) Curr Drug Targets , vol.7 , Issue.8 , pp. 923-934
    • Steiner, E.1    Holzmann, K.2    Elbling, L.3    Micksche, M.4    Berger, W.5
  • 100
    • 84897406427 scopus 로고    scopus 로고
    • PTEN regulates BCRP/ABCG2 and the side population through the PI3K/Akt pathway in chronic myeloid leukemia
    • PID: 24603487, PMID: 24603487
    • Huang FF, Zhang L, Wu DS, Yuan XY1, Chen FP1, Zeng H, et al. PTEN regulates BCRP/ABCG2 and the side population through the PI3K/Akt pathway in chronic myeloid leukemia. PLoS ONE. 2014;9(3):e88298. PMID: 24603487.
    • (2014) PLoS ONE , vol.9 , Issue.3 , pp. e88298
    • Huang, F.F.1    Zhang, L.2    Wu, D.S.3    Yuan, X.Y.4    Chen, F.P.5    Zeng, H.6
  • 101
    • 49149114863 scopus 로고    scopus 로고
    • Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells
    • PID: 18619946, COI: 1:CAS:528:DC%2BD1cXhtVSitbfN, PMID: 18619946
    • Zhu H, Wu H, Liu X, Evans BR, Medina DJ, Liu CG, et al. Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem Pharmacol. 2008;76(5):582–8. PMID: 18619946.
    • (2008) Biochem Pharmacol , vol.76 , Issue.5 , pp. 582-588
    • Zhu, H.1    Wu, H.2    Liu, X.3    Evans, B.R.4    Medina, D.J.5    Liu, C.G.6
  • 102
    • 77956648184 scopus 로고    scopus 로고
    • MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells
    • PID: 20624637, COI: 1:CAS:528:DC%2BC3cXhtFClsbvL, PMID: 20624637
    • Li Z, Hu S, Wang J, Cai J, Xiao L, Yu L, et al. MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells. Gynecol Oncol. 2010;119(1):125–30. PMID: 20624637.
    • (2010) Gynecol Oncol , vol.119 , Issue.1 , pp. 125-130
    • Li, Z.1    Hu, S.2    Wang, J.3    Cai, J.4    Xiao, L.5    Yu, L.6
  • 103
    • 79960790320 scopus 로고    scopus 로고
    • IL-10 and TGF-β2 are overexpressed in tumor spheres cultured from human gliomas
    • PID: 21088899, COI: 1:CAS:528:DC%2BC3MXlsVGisbo%3D, PMID: 21088899
    • Qiu B, Zhang D, Wang C, Tao J, Tie X, Qiao Y, et al. IL-10 and TGF-β2 are overexpressed in tumor spheres cultured from human gliomas. Mol Biol Rep. 2011;38(5):3585–91. PMID: 21088899.
    • (2011) Mol Biol Rep , vol.38 , Issue.5 , pp. 3585-3591
    • Qiu, B.1    Zhang, D.2    Wang, C.3    Tao, J.4    Tie, X.5    Qiao, Y.6
  • 104
    • 84869232447 scopus 로고    scopus 로고
    • IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival
    • PID: 22932670, COI: 1:CAS:528:DC%2BC38Xhs12jur7I, PMID: 22932670
    • Wainwright DA, Balyasnikova IV, Chang AL, Ahmed AU, Moon KS, Auffinger B, et al. IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival. Clin Cancer Res. 2012;18(22):6110–21. PMID: 22932670.
    • (2012) Clin Cancer Res , vol.18 , Issue.22 , pp. 6110-6121
    • Wainwright, D.A.1    Balyasnikova, I.V.2    Chang, A.L.3    Ahmed, A.U.4    Moon, K.S.5    Auffinger, B.6
  • 105
    • 35748975652 scopus 로고    scopus 로고
    • Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy
    • PID: 17522861, COI: 1:CAS:528:DC%2BD2sXht1aqs77P, PMID: 17522861
    • Jordan JT, Sun W, Hussain SF, DeAngulo G, Prabhu SS, Heimberger AB, et al. Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy. Cancer Immunol Immunother. 2008;57(1):123–31. PMID: 17522861.
    • (2008) Cancer Immunol Immunother , vol.57 , Issue.1 , pp. 123-131
    • Jordan, J.T.1    Sun, W.2    Hussain, S.F.3    DeAngulo, G.4    Prabhu, S.S.5    Heimberger, A.B.6
  • 107
    • 84862994725 scopus 로고    scopus 로고
    • Mechanisms of immune evasion by gliomas
    • PID: 22639159, COI: 1:CAS:528:DC%2BC38XhvVWht73I, PMID: 22639159
    • Rolle CE, Sengupta S, Lesniak MS. Mechanisms of immune evasion by gliomas. Adv Exp Med Biol. 2012;746:53–76. PMID: 22639159.
    • (2012) Adv Exp Med Biol , vol.746 , pp. 53-76
    • Rolle, C.E.1    Sengupta, S.2    Lesniak, M.S.3
  • 108
    • 14744292280 scopus 로고    scopus 로고
    • Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain
    • PID: 15716863, COI: 1:CAS:528:DC%2BD2MXhtlertL8%3D, PMID: 15716863
    • Zagzag D, Salnikow K, Chiriboga L, Yee H, Lan L, Ali MA, et al. Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain. Lab Invest. 2005;85(3):328–41. PMID: 15716863.
    • (2005) Lab Invest , vol.85 , Issue.3 , pp. 328-341
    • Zagzag, D.1    Salnikow, K.2    Chiriboga, L.3    Yee, H.4    Lan, L.5    Ali, M.A.6
  • 109
    • 84877133408 scopus 로고    scopus 로고
    • Exosomes from murine-derived GL26 cells promote glioblastoma tumor growth by reducing number and function of CD8 + T cells
    • PID: 23534743, PMID: 23534743
    • Liu ZM, Wang YB, Yuan XH. Exosomes from murine-derived GL26 cells promote glioblastoma tumor growth by reducing number and function of CD8 + T cells. Asian Pac J Cancer Prev. 2013;14(1):309–14. PMID: 23534743.
    • (2013) Asian Pac J Cancer Prev , vol.14 , Issue.1 , pp. 309-314
    • Liu, Z.M.1    Wang, Y.B.2    Yuan, X.H.3
  • 110
    • 67651102904 scopus 로고    scopus 로고
    • Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma
    • PID: 19351960, COI: 1:CAS:528:DC%2BD1MXnsVSktr4%3D, PMID: 19351960
    • Krejsgaard T, Vetter-Kauczok CS, Woetmann A, Kneitz H, Eriksen KW, Lovato P, et al. Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma. Blood. 2009;113(23):5896–904. PMID: 19351960.
    • (2009) Blood , vol.113 , Issue.23 , pp. 5896-5904
    • Krejsgaard, T.1    Vetter-Kauczok, C.S.2    Woetmann, A.3    Kneitz, H.4    Eriksen, K.W.5    Lovato, P.6
  • 111
    • 0032560522 scopus 로고    scopus 로고
    • Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase
    • PID: 9636152, COI: 1:CAS:528:DyaK1cXktFCht70%3D, PMID: 9636152
    • Malek SN, Dordai DI, Reim J, Dintzis H, Desiderio S. Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase. Proc Natl Acad Sci USA. 1998;95(13):7351–6. PMID: 9636152.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.13 , pp. 7351-7356
    • Malek, S.N.1    Dordai, D.I.2    Reim, J.3    Dintzis, H.4    Desiderio, S.5
  • 112
    • 0033840527 scopus 로고    scopus 로고
    • Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta
    • PID: 10930463, COI: 1:CAS:528:DC%2BD3cXmtV2rtbs%3D, PMID: 10930463
    • Saharinen J, Keski-Oja J. Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta. Mol Biol Cell. 2000;11(8):2691–704. PMID: 10930463.
    • (2000) Mol Biol Cell , vol.11 , Issue.8 , pp. 2691-2704
    • Saharinen, J.1    Keski-Oja, J.2
  • 113
    • 47349123215 scopus 로고    scopus 로고
    • Fibronectin and heparin binding domains of latent TGF-beta binding protein (LTBP)-4 mediate matrix targeting and cell adhesion
    • PID: 18585707, COI: 1:CAS:528:DC%2BD1cXptVeku78%3D, PMID: 18585707
    • Kantola AK, Keski-Oja J, Koli K. Fibronectin and heparin binding domains of latent TGF-beta binding protein (LTBP)-4 mediate matrix targeting and cell adhesion. Exp Cell Res. 2008;314(13):2488–500. PMID: 18585707.
    • (2008) Exp Cell Res , vol.314 , Issue.13 , pp. 2488-2500
    • Kantola, A.K.1    Keski-Oja, J.2    Koli, K.3
  • 114
    • 5444255239 scopus 로고    scopus 로고
    • Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung
    • PID: 15466481, COI: 1:CAS:528:DC%2BD2cXosVOiu7Y%3D, PMID: 15466481
    • Koli K, Wempe F, Sterner-Kock A, Kantola A, Komor M, Hofmann WK, et al. Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung. J Cell Biol. 2004;167(1):123–33. PMID: 15466481.
    • (2004) J Cell Biol , vol.167 , Issue.1 , pp. 123-133
    • Koli, K.1    Wempe, F.2    Sterner-Kock, A.3    Kantola, A.4    Komor, M.5    Hofmann, W.K.6
  • 115
    • 84860590379 scopus 로고    scopus 로고
    • Latent transforming growth factor binding protein 4 (LTBP4) is downregulated in mouse and human DCIS and mammary carcinomas
    • COI: 1:CAS:528:DC%2BC3MXhsFWjtbzO, PMID: 21468687
    • Kretschmer C, Conradi A, Kemmner W, Sterner-Kock A. Latent transforming growth factor binding protein 4 (LTBP4) is downregulated in mouse and human DCIS and mammary carcinomas. Cell Oncol (Dordr). 2011;34(5):419–34. PMID: 21468687.
    • (2011) Cell Oncol (Dordr) , vol.34 , Issue.5 , pp. 419-434
    • Kretschmer, C.1    Conradi, A.2    Kemmner, W.3    Sterner-Kock, A.4
  • 116
    • 84878542750 scopus 로고    scopus 로고
    • Latent transforming growth factor β-binding protein 4 is downregulated in esophageal cancer via promoter methylation
    • PID: 23741501, COI: 1:CAS:528:DC%2BC3sXpslOmtrk%3D, PMID: 23741501
    • Bultmann I, Conradi A, Kretschmer C, Sterner-Kock A. Latent transforming growth factor β-binding protein 4 is downregulated in esophageal cancer via promoter methylation. PLoS ONE. 2013;8(5):e65614. PMID: 23741501.
    • (2013) PLoS ONE , vol.8 , Issue.5 , pp. e65614
    • Bultmann, I.1    Conradi, A.2    Kretschmer, C.3    Sterner-Kock, A.4
  • 117
    • 79960147502 scopus 로고    scopus 로고
    • Exosome isolation for proteomic analyses and RNA profiling
    • PID: 21468952, COI: 1:CAS:528:DC%2BC3MXntlaktrk%3D, PMID: 21468952
    • Taylor DD, Zacharias W, Gercel-Taylor C. Exosome isolation for proteomic analyses and RNA profiling. Methods Mol Biol. 2011;728:235–46. PMID: 21468952.
    • (2011) Methods Mol Biol , vol.728 , pp. 235-246
    • Taylor, D.D.1    Zacharias, W.2    Gercel-Taylor, C.3
  • 118
    • 84867575631 scopus 로고    scopus 로고
    • Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers
    • PID: 22785172, COI: 1:CAS:528:DC%2BC38XhsFSnsr%2FM, PMID: 22785172
    • Alvarez ML, Khosroheidari M, Kanchi Ravi R, DiStefano JK. Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers. Kidney Int. 2012;82(9):1024–32. PMID: 22785172.
    • (2012) Kidney Int , vol.82 , Issue.9 , pp. 1024-1032
    • Alvarez, M.L.1    Khosroheidari, M.2    Kanchi Ravi, R.3    DiStefano, J.K.4
  • 119
    • 84866383967 scopus 로고    scopus 로고
    • Impact of biofluid viscosity on size and sedimentation efficiency of the isolated microvesicles
    • PID: 22661955, COI: 1:CAS:528:DC%2BC38XptV2itrk%3D, PMID: 22661955
    • Momen-Heravi F, Balaj L, Alian S, Trachtenberg AJ, Hochberg FH, Skog J, et al. Impact of biofluid viscosity on size and sedimentation efficiency of the isolated microvesicles. Front Physiol. 2012;3:162. PMID: 22661955.
    • (2012) Front Physiol , vol.3 , pp. 162
    • Momen-Heravi, F.1    Balaj, L.2    Alian, S.3    Trachtenberg, A.J.4    Hochberg, F.H.5    Skog, J.6
  • 120
    • 24644461021 scopus 로고    scopus 로고
    • Association of chromosome 7, chromosome 10 and EGFR gene amplification in glioblastoma multiforme
    • PID: 16167544, COI: 1:STN:280:DC%2BD2MvpsF2qtw%3D%3D, PMID: 16167544
    • Lopez-Gines C, Cerda-Nicolas M, Gil-Benso R, Pellin A, Lopez-Guerrero JA, Callaghan R, et al. Association of chromosome 7, chromosome 10 and EGFR gene amplification in glioblastoma multiforme. Clin Neuropathol. 2005;24:209–18. PMID: 16167544.
    • (2005) Clin Neuropathol , vol.24 , pp. 209-218
    • Lopez-Gines, C.1    Cerda-Nicolas, M.2    Gil-Benso, R.3    Pellin, A.4    Lopez-Guerrero, J.A.5    Callaghan, R.6
  • 121
    • 84878776776 scopus 로고    scopus 로고
    • Screening for EGFR amplifications with a novel method and their significance for the outcome of glioblastoma patients
    • PID: 23762372, PMID: 23762372
    • Bieńkowski M, Piaskowski S, Stoczyńska-Fidelus E, Szybka M, Banaszczyk M, Witusik-Perkowska M, et al. Screening for EGFR amplifications with a novel method and their significance for the outcome of glioblastoma patients. PLoS ONE. 2013;8(6):e65444. PMID: 23762372.
    • (2013) PLoS ONE , vol.8 , Issue.6 , pp. e65444
    • Bieńkowski, M.1    Piaskowski, S.2    Stoczyńska-Fidelus, E.3    Szybka, M.4    Banaszczyk, M.5    Witusik-Perkowska, M.6
  • 122
    • 0029964091 scopus 로고    scopus 로고
    • Patterns of epidermal growth factor receptor amplification in malignant gliomas
    • PID: 8644846, COI: 1:STN:280:DyaK283kslKrsA%3D%3D, PMID: 8644846
    • Sauter G, Maeda T, Waldman FM, Davis RL, Feuerstein BG. Patterns of epidermal growth factor receptor amplification in malignant gliomas. Am J Pathol. 1996;148(4):1047–53. PMID: 8644846.
    • (1996) Am J Pathol , vol.148 , Issue.4 , pp. 1047-1053
    • Sauter, G.1    Maeda, T.2    Waldman, F.M.3    Davis, R.L.4    Feuerstein, B.G.5
  • 123
    • 84899550794 scopus 로고    scopus 로고
    • Mutation of isocitrate dehydrogenase 1 induces glioma cell proliferation via nuclear factor-κB activation in a hypoxia-inducible factor 1α-dependent manner
    • PID: 24626950, COI: 1:CAS:528:DC%2BC2cXhtVeltLbO, PMID: 24626950
    • Wang G, Sai K, Gong F, Yang Q, Chen F, Lin J. Mutation of isocitrate dehydrogenase 1 induces glioma cell proliferation via nuclear factor-κB activation in a hypoxia-inducible factor 1α-dependent manner. Mol Med Rep. 2014;9:1799–805. PMID: 24626950.
    • (2014) Mol Med Rep , vol.9 , pp. 1799-1805
    • Wang, G.1    Sai, K.2    Gong, F.3    Yang, Q.4    Chen, F.5    Lin, J.6
  • 124
    • 72049125350 scopus 로고    scopus 로고
    • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
    • PID: 19935646, COI: 1:CAS:528:DC%2BD1MXhsVGlurzE, PMID: 19935646
    • Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 2009;462(7274):739–44. PMID: 19935646.
    • (2009) Nature , vol.462 , Issue.7274 , pp. 739-744
    • Dang, L.1    White, D.W.2    Gross, S.3    Bennett, B.D.4    Bittinger, M.A.5    Driggers, E.M.6
  • 125
    • 84870538996 scopus 로고    scopus 로고
    • A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation
    • PID: 22899282, COI: 1:CAS:528:DC%2BC38XhvVWgsbfO, PMID: 22899282
    • Duncan CG, Barwick BG, Jin G, Rago C, Kapoor-Vazirani P, Powell DR, et al. A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. Genome Res. 2012;22(12):2339–55. PMID: 22899282.
    • (2012) Genome Res , vol.22 , Issue.12 , pp. 2339-2355
    • Duncan, C.G.1    Barwick, B.G.2    Jin, G.3    Rago, C.4    Kapoor-Vazirani, P.5    Powell, D.R.6
  • 126
    • 84865218876 scopus 로고    scopus 로고
    • Molecular pathogenesis of IDH mutations in gliomas
    • PID: 22399191, COI: 1:CAS:528:DC%2BC38XhtVOgsLvN, PMID: 22399191
    • Ichimura K. Molecular pathogenesis of IDH mutations in gliomas. Brain Tumor Pathol. 2012;29(3):131–9. PMID: 22399191.
    • (2012) Brain Tumor Pathol , vol.29 , Issue.3 , pp. 131-139
    • Ichimura, K.1
  • 127
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • COI: 1:CAS:528:DC%2BC3cXkvFKgsL4%3D, PMID: 20129251
    • Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 2010;17(1):98–110. PMID: 20129251.
    • (2010) Cancer Cell , vol.17 , Issue.1 , pp. 98-110
    • Verhaak, R.G.1    Hoadley, K.A.2    Purdom, E.3    Wang, V.4    Qi, Y.5    Wilkerson, M.D.6
  • 128
    • 84880339763 scopus 로고    scopus 로고
    • BEAMing and droplet digital PCR analysis of mutant IDH1 mRNA in glioma patient serum and cerebrospinal fluid extracellular vesicles
    • PID: 23881452, PMID: 23881452
    • Chen WW, Balaj L, Liau LM, Samuels ML, Kotsopoulos SK, Maguire CA, et al. BEAMing and droplet digital PCR analysis of mutant IDH1 mRNA in glioma patient serum and cerebrospinal fluid extracellular vesicles. Mol Ther Nucleic Acids. 2013;2:e109. PMID: 23881452.
    • (2013) Mol Ther Nucleic Acids , vol.2 , pp. e109
    • Chen, W.W.1    Balaj, L.2    Liau, L.M.3    Samuels, M.L.4    Kotsopoulos, S.K.5    Maguire, C.A.6
  • 129
    • 0036328245 scopus 로고    scopus 로고
    • Identification and relationship of HER-2/neu overexpression to short-term mortality in primary malignant brain tumors
    • PID: 12168843, COI: 1:CAS:528:DC%2BD38XmsFWks7s%3D, PMID: 12168843
    • Forseen SE, Potti A, Koka V, Koch M, Fraiman G, Levitt R. Identification and relationship of HER-2/neu overexpression to short-term mortality in primary malignant brain tumors. Anticancer Res. 2002;22:1599–602. PMID: 12168843.
    • (2002) Anticancer Res , vol.22 , pp. 1599-1602
    • Forseen, S.E.1    Potti, A.2    Koka, V.3    Koch, M.4    Fraiman, G.5    Levitt, R.6
  • 130
    • 84878468245 scopus 로고    scopus 로고
    • Droplet digital PCR measurement of HER2 copy number alteration in formalin-fixed paraffin-embedded breast carcinoma tissue
    • PID: 23358413, COI: 1:CAS:528:DC%2BC3sXpslKgurs%3D, PMID: 23358413
    • Belgrader P, Tanner SC, Regan JF, Koehler R, Hindson BJ, Brown AS. Droplet digital PCR measurement of HER2 copy number alteration in formalin-fixed paraffin-embedded breast carcinoma tissue. Clin Chem. 2013;59(6):991–4. PMID: 23358413.
    • (2013) Clin Chem , vol.59 , Issue.6 , pp. 991-994
    • Belgrader, P.1    Tanner, S.C.2    Regan, J.F.3    Koehler, R.4    Hindson, B.J.5    Brown, A.S.6
  • 131
    • 84864577733 scopus 로고    scopus 로고
    • Direct quantification of microRNA at low picomolar level in sera of glioma patients using a competitive hybridization followed by amplified voltammetric detection
    • PID: 22788545, COI: 1:CAS:528:DC%2BC38XptF2nt7c%3D, PMID: 22788545
    • Wang J, Yi X, Tang H, Han H, Wu M, Zhou F. Direct quantification of microRNA at low picomolar level in sera of glioma patients using a competitive hybridization followed by amplified voltammetric detection. Anal Chem. 2012;84(15):6400–6. PMID: 22788545.
    • (2012) Anal Chem , vol.84 , Issue.15 , pp. 6400-6406
    • Wang, J.1    Yi, X.2    Tang, H.3    Han, H.4    Wu, M.5    Zhou, F.6
  • 132
    • 84869882026 scopus 로고    scopus 로고
    • Plasma specific miRNAs as predictive biomarkers for diagnosis and prognosis of glioma
    • PMID: 23174013
    • Wang Q, Li P, Li A, Jiang W, Wang H, Wang J, et al. Plasma specific miRNAs as predictive biomarkers for diagnosis and prognosis of glioma. J Exp Clin Cancer Res. 2013;31:97. PMID: 23174013.
    • (2013) J Exp Clin Cancer Res , vol.31 , pp. 97
    • Wang, Q.1    Li, P.2    Li, A.3    Jiang, W.4    Wang, H.5    Wang, J.6
  • 133
    • 84862192105 scopus 로고    scopus 로고
    • MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity
    • PID: 22492962, COI: 1:CAS:528:DC%2BC38Xhtl2hsb7K, PMID: 22492962
    • Teplyuk NM, Mollenhauer B, Gabriely G, Giese A, Kim E, Smolsky M, et al. MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity. Neuro Oncol. 2012;14:689–700. PMID: 22492962.
    • (2012) Neuro Oncol , vol.14 , pp. 689-700
    • Teplyuk, N.M.1    Mollenhauer, B.2    Gabriely, G.3    Giese, A.4    Kim, E.5    Smolsky, M.6
  • 134
    • 84892861394 scopus 로고    scopus 로고
    • Analysis of expression of microRNAs and genes involved in the control of key signaling mechanisms that support or inhibit development of brain tumors of different grades
    • PID: 24412320, COI: 1:CAS:528:DC%2BC2cXjslKkt7s%3D, PMID: 24412320
    • Koshkin PA, Chistiakov DA, Nikitin AG, Konovalov AN, Potapov AA, Usachev DY, et al. Analysis of expression of microRNAs and genes involved in the control of key signaling mechanisms that support or inhibit development of brain tumors of different grades. Clin Chim Acta. 2014;430:55–62. PMID: 24412320.
    • (2014) Clin Chim Acta , vol.430 , pp. 55-62
    • Koshkin, P.A.1    Chistiakov, D.A.2    Nikitin, A.G.3    Konovalov, A.N.4    Potapov, A.A.5    Usachev, D.Y.6
  • 135
    • 84896971533 scopus 로고    scopus 로고
    • A small noncoding RNA signature found in exosomes of GBM patient serum as a diagnostic tool
    • PID: 24435880, COI: 1:CAS:528:DC%2BC2cXkslCrurk%3D, PMID: 24435880
    • Manterola L, Guruceaga E, Gállego Pérez-Larraya J, González-Huarriz M, Jauregui P, Tejada S, et al. A small noncoding RNA signature found in exosomes of GBM patient serum as a diagnostic tool. Neuro Oncol. 2014;16:520–7. PMID: 24435880.
    • (2014) Neuro Oncol , vol.16 , pp. 520-527
    • Manterola, L.1    Guruceaga, E.2    Gállego Pérez-Larraya, J.3    González-Huarriz, M.4    Jauregui, P.5    Tejada, S.6
  • 136
    • 84856464305 scopus 로고    scopus 로고
    • Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320
    • PID: 22179046, PMID: 22179046
    • Bronisz A, Godlewski J, Wallace JA, Merchant AS, Nowicki MO, Mathsyaraja H, et al. Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nat Cell Biol. 2011;14(2):159–67. PMID: 22179046.
    • (2011) Nat Cell Biol , vol.14 , Issue.2 , pp. 159-167
    • Bronisz, A.1    Godlewski, J.2    Wallace, J.A.3    Merchant, A.S.4    Nowicki, M.O.5    Mathsyaraja, H.6
  • 137
    • 7644237187 scopus 로고    scopus 로고
    • Tumor-host immune interactions and dendritic cell dysfunction
    • PID: 15530555, COI: 1:CAS:528:DC%2BD2MXivVyhsbo%3D, PMID: 15530555
    • Yang L, Carbone DP. Tumor-host immune interactions and dendritic cell dysfunction. Adv Cancer Res. 2004;92:13–27. PMID: 15530555.
    • (2004) Adv Cancer Res , vol.92 , pp. 13-27
    • Yang, L.1    Carbone, D.P.2
  • 138
    • 70450205309 scopus 로고    scopus 로고
    • Dendritic cell vaccines for brain tumors
    • PID: 19944973, PMID: 19944973
    • Kim W, Liau LM. Dendritic cell vaccines for brain tumors. Neurosurg Clin N Am. 2010;21(1):139–57. PMID: 19944973.
    • (2010) Neurosurg Clin N Am , vol.21 , Issue.1 , pp. 139-157
    • Kim, W.1    Liau, L.M.2
  • 139
    • 80052637225 scopus 로고    scopus 로고
    • Exosome-loaded dendritic cells elicit tumor-specific CD8+ cytotoxic T cells in patients with glioma
    • PID: 21336773, COI: 1:CAS:528:DC%2BC3MXhtFCrtbzO, PMID: 21336773
    • Bu N, Wu H, Sun B, Zhang G, Zhan S, Zhang R, et al. Exosome-loaded dendritic cells elicit tumor-specific CD8+ cytotoxic T cells in patients with glioma. J Neurooncol. 2011;104(3):659–67. PMID: 21336773.
    • (2011) J Neurooncol , vol.104 , Issue.3 , pp. 659-667
    • Bu, N.1    Wu, H.2    Sun, B.3    Zhang, G.4    Zhan, S.5    Zhang, R.6
  • 140
    • 10744229153 scopus 로고    scopus 로고
    • Exosomes as potent cell-free peptide-based vaccine I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells
    • PID: 14764678, PMID: 14764678
    • André F, Chaput N, Schartz NE, Flament C, Aubert N, Bernard J, et al. Exosomes as potent cell-free peptide-based vaccine I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells. J Immunol. 2004;172(4):2126–36. PMID: 14764678.
    • (2004) J Immunol , vol.172 , Issue.4 , pp. 2126-2136
    • André, F.1    Chaput, N.2    Schartz, N.E.3    Flament, C.4    Aubert, N.5    Bernard, J.6
  • 141
    • 77957016314 scopus 로고    scopus 로고
    • Mesenchymal stem cells: a promising targeted-delivery vehicle in cancer gene therapy
    • PID: 20493219, COI: 1:CAS:528:DC%2BC3cXht1SnsrvK, PMID: 20493219
    • Hu YL, Fu YH, Tabata Y, Gao JQ. Mesenchymal stem cells: a promising targeted-delivery vehicle in cancer gene therapy. J Control Release. 2010;147(2):154–62. PMID: 20493219.
    • (2010) J Control Release , vol.147 , Issue.2 , pp. 154-162
    • Hu, Y.L.1    Fu, Y.H.2    Tabata, Y.3    Gao, J.Q.4
  • 142
    • 84886625070 scopus 로고    scopus 로고
    • Delivery of functional anti-miR-9 by mesenchymal stem cell-derived exosomes to glioblastoma multiforme cells conferred chemosensitivity
    • PID: 24084846, PMID: 24084846
    • Munoz JL, Bliss SA, Greco SJ, Ramkissoon SH, Ligon KL, Rameshwar P, et al. Delivery of functional anti-miR-9 by mesenchymal stem cell-derived exosomes to glioblastoma multiforme cells conferred chemosensitivity. Mol Ther Nucleic Acids. 2013;2:e126. PMID: 24084846.
    • (2013) Mol Ther Nucleic Acids , vol.2 , pp. e126
    • Munoz, J.L.1    Bliss, S.A.2    Greco, S.J.3    Ramkissoon, S.H.4    Ligon, K.L.5    Rameshwar, P.6
  • 143
    • 84881186425 scopus 로고    scopus 로고
    • Characterization of the blood–brain barrier of metastatic and primary malignant neoplasms
    • PID: 23621605, PMID: 23621605
    • Nduom EK, Yang C, Merrill MJ, Zhuang Z, Lonser RR. Characterization of the blood–brain barrier of metastatic and primary malignant neoplasms. J Neurosurg. 2013;119(2):427–33. PMID: 23621605.
    • (2013) J Neurosurg , vol.119 , Issue.2 , pp. 427-433
    • Nduom, E.K.1    Yang, C.2    Merrill, M.J.3    Zhuang, Z.4    Lonser, R.R.5


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