메뉴 건너뛰기




Volumn 230, Issue 3, 2015, Pages 504-509

p27 and Leukemia: Cell Cycle and Beyond

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1C; CYCLINE; ONCOPROTEIN; PROTEIN P15; PROTEIN P16; PROTEIN P18; PROTEIN P19; PROTEIN P21; PROTEIN P27; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MICROTUBULE ASSOCIATED PROTEIN;

EID: 84920896917     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24819     Document Type: Review
Times cited : (56)

References (132)
  • 2
    • 69249220221 scopus 로고    scopus 로고
    • Cytoplasmic localization of Jab1 and p27 Kip1 might be associated with invasiveness of papillary thyroid carcinoma
    • Ahn J, Hong SA, Lee SE, Kim J, Oh YS, Park SJ, Chung YJ. 2009. Cytoplasmic localization of Jab1 and p27 Kip1 might be associated with invasiveness of papillary thyroid carcinoma. Endocr J 56:707-713.
    • (2009) Endocr J , vol.56 , pp. 707-713
    • Ahn, J.1    Hong, S.A.2    Lee, S.E.3    Kim, J.4    Oh, Y.S.5    Park, S.J.6    Chung, Y.J.7
  • 3
    • 0035093090 scopus 로고    scopus 로고
    • Role of Sp1 in the induction of p27 gene expression in vascular smooth muscle cells in vitro and after balloon angioplasty
    • Andres V, Urena J, Poch E, Chen D, Goukassian D. 2001. Role of Sp1 in the induction of p27 gene expression in vascular smooth muscle cells in vitro and after balloon angioplasty. Arterioscler Thromb Vasc Biol 21:342-347.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 342-347
    • Andres, V.1    Urena, J.2    Poch, E.3    Chen, D.4    Goukassian, D.5
  • 5
    • 27344444026 scopus 로고    scopus 로고
    • Bcr-Abl activates the AKT/Fox O3 signalling pathway to restrict transforming growth factor-beta-mediated cytostatic signals
    • Atfi A, Abecassis L, Bourgeade MF. 2005. Bcr-Abl activates the AKT/Fox O3 signalling pathway to restrict transforming growth factor-beta-mediated cytostatic signals. EMBO Rep 6:985-991.
    • (2005) EMBO Rep , vol.6 , pp. 985-991
    • Atfi, A.1    Abecassis, L.2    Bourgeade, M.F.3
  • 6
    • 18844415826 scopus 로고    scopus 로고
    • The yeast cyclin-dependent kinase inhibitor Sic1 and mammalian p27Kip1 are functional homologues with a structurally conserved inhibitory domain
    • Barberis M, De Gioia L, Ruzzene M, Sarno S, Coccetti P, Fantucci P, Vanoni M, Alberghina L. 2005. The yeast cyclin-dependent kinase inhibitor Sic1 and mammalian p27Kip1 are functional homologues with a structurally conserved inhibitory domain. Biochem J 387:639-647.
    • (2005) Biochem J , vol.387 , pp. 639-647
    • Barberis, M.1    De Gioia, L.2    Ruzzene, M.3    Sarno, S.4    Coccetti, P.5    Fantucci, P.6    Vanoni, M.7    Alberghina, L.8
  • 7
    • 77955044544 scopus 로고    scopus 로고
    • Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis
    • Bellodi C, Krasnykh O, Haynes N, Theodoropoulou M, Peng G, Montanaro L, Ruggero D. 2010. Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis. Cancer Res 70:6026-6035.
    • (2010) Cancer Res , vol.70 , pp. 6026-6035
    • Bellodi, C.1    Krasnykh, O.2    Haynes, N.3    Theodoropoulou, M.4    Peng, G.5    Montanaro, L.6    Ruggero, D.7
  • 8
    • 38849187293 scopus 로고    scopus 로고
    • CDK inhibitors: cell cycle regulators and beyond
    • Besson A, Dowdy SF, Roberts JM. 2008. CDK inhibitors: cell cycle regulators and beyond. Dev Cell 14:159-169.
    • (2008) Dev Cell , vol.14 , pp. 159-169
    • Besson, A.1    Dowdy, S.F.2    Roberts, J.M.3
  • 9
    • 29944440513 scopus 로고    scopus 로고
    • A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression
    • Besson A, Gurian-West M, Chen X, Kelly-Spratt KS, Kemp CJ, Roberts JM. 2006. A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression. Genes Dev 20:47-64.
    • (2006) Genes Dev , vol.20 , pp. 47-64
    • Besson, A.1    Gurian-West, M.2    Chen, X.3    Kelly-Spratt, K.S.4    Kemp, C.J.5    Roberts, J.M.6
  • 10
    • 1942466518 scopus 로고    scopus 로고
    • P27Kip1 modulates cell migration through the regulation of RhoA activation
    • Besson A, Gurian-West M, Schmidt A, Hall A, Roberts JM. 2004. P27Kip1 modulates cell migration through the regulation of RhoA activation. Genes Dev 18:862-876.
    • (2004) Genes Dev , vol.18 , pp. 862-876
    • Besson, A.1    Gurian-West, M.2    Schmidt, A.3    Hall, A.4    Roberts, J.M.5
  • 11
    • 0030845187 scopus 로고    scopus 로고
    • Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4
    • Blain SW, Montalvo E, Massague J. 1997. Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4. J Biol Chem 272:25863-25872.
    • (1997) J Biol Chem , vol.272 , pp. 25863-25872
    • Blain, S.W.1    Montalvo, E.2    Massague, J.3
  • 12
    • 0036645678 scopus 로고    scopus 로고
    • A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression
    • Boehm M, Yoshimoto T, Crook MF, Nallamshetty S, True A, Nabel GJ, Nabel EG. 2002. A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression. EMBO J 21:3390-3401.
    • (2002) EMBO J , vol.21 , pp. 3390-3401
    • Boehm, M.1    Yoshimoto, T.2    Crook, M.F.3    Nallamshetty, S.4    True, A.5    Nabel, G.J.6    Nabel, E.G.7
  • 14
    • 0033176887 scopus 로고    scopus 로고
    • SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
    • Carrano AC, Eytan E, Hershko A, Pagano M. 1999. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat Cell Biol 1:193-199.
    • (1999) Nat Cell Biol , vol.1 , pp. 193-199
    • Carrano, A.C.1    Eytan, E.2    Hershko, A.3    Pagano, M.4
  • 15
    • 0034646247 scopus 로고    scopus 로고
    • The amino terminus of the mixed lineage leukemia protein (MLL) promotes cell cycle arrest and monocytic differentiation
    • Caslini C, Shilatifard A, Yang L, Hess JL. 2000. The amino terminus of the mixed lineage leukemia protein (MLL) promotes cell cycle arrest and monocytic differentiation. Proc Natl Acad Sci USA 97:2797-2802.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2797-2802
    • Caslini, C.1    Shilatifard, A.2    Yang, L.3    Hess, J.L.4
  • 16
    • 0032477854 scopus 로고    scopus 로고
    • Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)
    • Cheng M, Sexl V, Sherr CJ, Roussel MF. 1998. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). Proc Natl Acad Sci USA 95:1091-1096.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1091-1096
    • Cheng, M.1    Sexl, V.2    Sherr, C.J.3    Roussel, M.F.4
  • 17
    • 34547122492 scopus 로고    scopus 로고
    • BCR-tyrosine 177 plays an essential role in Ras and Akt activation and in human hematopoietic progenitor transformation in chronic myelogenous leukemia
    • Chu S, Li L, Singh H, Bhatia R. 2007b. BCR-tyrosine 177 plays an essential role in Ras and Akt activation and in human hematopoietic progenitor transformation in chronic myelogenous leukemia. Cancer Res 67:7045-7053.
    • (2007) Cancer Res , vol.67 , pp. 7045-7053
    • Chu, S.1    Li, L.2    Singh, H.3    Bhatia, R.4
  • 18
    • 77950951767 scopus 로고    scopus 로고
    • Role of BCR-ABL-Y177-mediated p27kip1 phosphorylation and cytoplasmic localization in enhanced proliferation of chronic myeloid leukemia progenitors
    • Chu S, McDonald T, Bhatia R. 2010. Role of BCR-ABL-Y177-mediated p27kip1 phosphorylation and cytoplasmic localization in enhanced proliferation of chronic myeloid leukemia progenitors. Leukemia 24:779-787.
    • (2010) Leukemia , vol.24 , pp. 779-787
    • Chu, S.1    McDonald, T.2    Bhatia, R.3
  • 21
    • 42549093634 scopus 로고    scopus 로고
    • Differential motility of p190bcr-abl- and p210bcr-abl-expressing cells: respective roles of Vav and Bcr-Abl GEFs
    • Daubon T, Chasseriau J, El Ali, Rivet A, Kitzis J, Constantin A, Bourmeyster B. 2008. Differential motility of p190bcr-abl- and p210bcr-abl-expressing cells: respective roles of Vav and Bcr-Abl GEFs. Oncogene 27:2673-2685.
    • (2008) Oncogene , vol.27 , pp. 2673-2685
    • Daubon, T.1    Chasseriau, J.2    El, A.3    Rivet, A.4    Kitzis, J.5    Constantin, A.6    Bourmeyster, B.7
  • 22
    • 2542489078 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G(0) by Mirk/dyrk1B kinase
    • Deng X, Mercer SE, Shah S, Ewton DZ, Friedman E. 2004. The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G(0) by Mirk/dyrk1B kinase. J Biol Chem 279:22498-22504.
    • (2004) J Biol Chem , vol.279 , pp. 22498-22504
    • Deng, X.1    Mercer, S.E.2    Shah, S.3    Ewton, D.Z.4    Friedman, E.5
  • 23
    • 35148901042 scopus 로고    scopus 로고
    • Relocalized p27Kip1 tumor suppressor functions as a cytoplasmic metastatic oncogene in melanoma
    • Denicourt C, Saenz CC, Datnow B, Cui XS, Dowdy SF. 2007. Relocalized p27Kip1 tumor suppressor functions as a cytoplasmic metastatic oncogene in melanoma. Cancer Res 67:9238-9243.
    • (2007) Cancer Res , vol.67 , pp. 9238-9243
    • Denicourt, C.1    Saenz, C.C.2    Datnow, B.3    Cui, X.S.4    Dowdy, S.F.5
  • 25
    • 2442650053 scopus 로고    scopus 로고
    • P27kip1 regulates the apoptotic response of gastric epithelial cells to Helicobacter pylori
    • Eguchi H, Carpentier S, Kim SS, Moss SF. 2004. P27kip1 regulates the apoptotic response of gastric epithelial cells to Helicobacter pylori. Gut 53:797-804.
    • (2004) Gut , vol.53 , pp. 797-804
    • Eguchi, H.1    Carpentier, S.2    Kim, S.S.3    Moss, S.F.4
  • 26
    • 0032511848 scopus 로고    scopus 로고
    • The murine gene p27Kip1 is haplo-insufficient for tumour suppression
    • Fero ML, Randel E, Gurley KE, Roberts JM, Kemp CJ. 1998. The murine gene p27Kip1 is haplo-insufficient for tumour suppression. Nature 396:177-180.
    • (1998) Nature , vol.396 , pp. 177-180
    • Fero, M.L.1    Randel, E.2    Gurley, K.E.3    Roberts, J.M.4    Kemp, C.J.5
  • 28
    • 0037047268 scopus 로고    scopus 로고
    • Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization
    • Fujita N, Sato S, Katayama K, Tsuruo T. 2002. Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization. J Biol Chem 277:28706-28713.
    • (2002) J Biol Chem , vol.277 , pp. 28706-28713
    • Fujita, N.1    Sato, S.2    Katayama, K.3    Tsuruo, T.4
  • 29
    • 1542677089 scopus 로고    scopus 로고
    • Phosphorylation of p27Kip1 at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 14-3-3 and cytoplasmic localization
    • Fujita N, Sato S, Tsuruo T. 2003. Phosphorylation of p27Kip1 at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 14-3-3 and cytoplasmic localization. J Biol Chem 278:49254-49260.
    • (2003) J Biol Chem , vol.278 , pp. 49254-49260
    • Fujita, N.1    Sato, S.2    Tsuruo, T.3
  • 32
    • 0034671745 scopus 로고    scopus 로고
    • BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway
    • Gesbert F, Sellers WR, Signoretti S, Loda M, Griffin JD. 2000. BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway. J Biol Chem 275:39223-39230.
    • (2000) J Biol Chem , vol.275 , pp. 39223-39230
    • Gesbert, F.1    Sellers, W.R.2    Signoretti, S.3    Loda, M.4    Griffin, J.D.5
  • 33
    • 0041308069 scopus 로고    scopus 로고
    • Cell cycle-dependent translation of p27 involves a responsive element in its 5'-UTR that overlaps with a uORF
    • Gopfert U, Kullmann M, Hengst L. 2003. Cell cycle-dependent translation of p27 involves a responsive element in its 5'-UTR that overlaps with a uORF. Hum Mol Genet 12:1767-1779.
    • (2003) Hum Mol Genet , vol.12 , pp. 1767-1779
    • Gopfert, U.1    Kullmann, M.2    Hengst, L.3
  • 35
    • 84880819318 scopus 로고    scopus 로고
    • Phosphorylation of p27(KIP1) homologs KRP6 and 7 by SNF1-related protein kinase-1 links plant energy homeostasis and cell proliferation
    • Guerinier T, Millan L, Crozet P, Oury C, Rey F, Valot B, Mathieu C, Vidal J, Hodges M, Thomas M, Glab N. 2013. Phosphorylation of p27(KIP1) homologs KRP6 and 7 by SNF1-related protein kinase-1 links plant energy homeostasis and cell proliferation. Plant J 75:515-525.
    • (2013) Plant J , vol.75 , pp. 515-525
    • Guerinier, T.1    Millan, L.2    Crozet, P.3    Oury, C.4    Rey, F.5    Valot, B.6    Mathieu, C.7    Vidal, J.8    Hodges, M.9    Thomas, M.10    Glab, N.11
  • 36
    • 0029670477 scopus 로고    scopus 로고
    • Translational control of p27Kip1 accumulation during the cell cycle
    • Hengst L, Reed SI. 1996. Translational control of p27Kip1 accumulation during the cell cycle. Science 271:1861-1864.
    • (1996) Science , vol.271 , pp. 1861-1864
    • Hengst, L.1    Reed, S.I.2
  • 38
    • 0033525188 scopus 로고    scopus 로고
    • RhoA stimulates p27(Kip) degradation through its regulation of cyclin E/CDK2 activity
    • Hu W, Bellone CJ, Baldassare JJ. 1999. RhoA stimulates p27(Kip) degradation through its regulation of cyclin E/CDK2 activity. J Biol Chem 274:3396-3401.
    • (1999) J Biol Chem , vol.274 , pp. 3396-3401
    • Hu, W.1    Bellone, C.J.2    Baldassare, J.J.3
  • 40
    • 0034682818 scopus 로고    scopus 로고
    • Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability
    • Ishida N, Kitagawa M, Hatakeyama S, Nakayama K. 2000. Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability. J Biol Chem 275:25146-25154.
    • (2000) J Biol Chem , vol.275 , pp. 25146-25154
    • Ishida, N.1    Kitagawa, M.2    Hatakeyama, S.3    Nakayama, K.4
  • 41
    • 80051802413 scopus 로고    scopus 로고
    • Phosphorylation of p27Kip1 by JAK2 directly links cytokine receptor signaling to cell cycle control
    • Jakel H, Weinl C, Hengst L. 2011. Phosphorylation of p27Kip1 by JAK2 directly links cytokine receptor signaling to cell cycle control. Oncogene 30:3502-3512.
    • (2011) Oncogene , vol.30 , pp. 3502-3512
    • Jakel, H.1    Weinl, C.2    Hengst, L.3
  • 42
    • 37549061066 scopus 로고    scopus 로고
    • Differential modification of p27Kip1 controls its cyclin D-cdk4 inhibitory activity
    • James MK, Ray A, Leznova D, Blain SW. 2008. Differential modification of p27Kip1 controls its cyclin D-cdk4 inhibitory activity. Mol Cell Biol 28:498-510.
    • (2008) Mol Cell Biol , vol.28 , pp. 498-510
    • James, M.K.1    Ray, A.2    Leznova, D.3    Blain, S.W.4
  • 43
    • 0034641709 scopus 로고    scopus 로고
    • Abnormal integrin-mediated regulation of chronic myelogenous leukemia CD34+ cell proliferation: BCR/ABL up-regulates the cyclin-dependent kinase inhibitor, p27Kip, which is relocated to the cell cytoplasm and incapable of regulating cdk2 activity
    • Jiang Y, Zhao RC, Verfaillie CM. 2000. Abnormal integrin-mediated regulation of chronic myelogenous leukemia CD34+ cell proliferation: BCR/ABL up-regulates the cyclin-dependent kinase inhibitor, p27Kip, which is relocated to the cell cytoplasm and incapable of regulating cdk2 activity. Proc Natl Acad Sci USA 97:10538-10543.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10538-10543
    • Jiang, Y.1    Zhao, R.C.2    Verfaillie, C.M.3
  • 46
    • 0031439355 scopus 로고    scopus 로고
    • Promoting apoptosis: a novel activity associated with the cyclin-dependent kinase inhibitor p27
    • Katayose Y, Kim M, Rakkar AN, Li Z, Cowan KH, Seth P. 1997. Promoting apoptosis: a novel activity associated with the cyclin-dependent kinase inhibitor p27. Cancer Res 57:5441-5445.
    • (1997) Cancer Res , vol.57 , pp. 5441-5445
    • Katayose, Y.1    Kim, M.2    Rakkar, A.N.3    Li, Z.4    Cowan, K.H.5    Seth, P.6
  • 47
    • 0027973043 scopus 로고
    • Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation
    • Kato JY, Matsuoka M, Polyak K, Massague J, Sherr CJ. 1994. Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation. Cell 79:487-496.
    • (1994) Cell , vol.79 , pp. 487-496
    • Kato, J.Y.1    Matsuoka, M.2    Polyak, K.3    Massague, J.4    Sherr, C.J.5
  • 48
    • 30344457896 scopus 로고    scopus 로고
    • Cdk5 phosphorylates and stabilizes p27kip1 contributing to actin organization and cortical neuronal migration
    • Kawauchi T, Chihama K, Nabeshima Y, Hoshino M. 2006. Cdk5 phosphorylates and stabilizes p27kip1 contributing to actin organization and cortical neuronal migration. Nat Cell Biol 8:17-26.
    • (2006) Nat Cell Biol , vol.8 , pp. 17-26
    • Kawauchi, T.1    Chihama, K.2    Nabeshima, Y.3    Hoshino, M.4
  • 49
    • 77951151894 scopus 로고    scopus 로고
    • Mitogenic regulation of p27(Kip1) gene is mediated by AP-1 transcription factors
    • Khattar E, Kumar V. 2010. Mitogenic regulation of p27(Kip1) gene is mediated by AP-1 transcription factors. J Biol Chem 285:4554-4561.
    • (2010) J Biol Chem , vol.285 , pp. 4554-4561
    • Khattar, E.1    Kumar, V.2
  • 50
    • 35548932785 scopus 로고    scopus 로고
    • Active FKHRL1 overcomes imatinib resistance in chronic myelogenous leukemia-derived cell lines via the production of tumor necrosis factor-related apoptosis-inducing ligand
    • Kikuchi S, Nagai T, Kunitama M, Kirito K, Ozawa K, Komatsu N. 2007. Active FKHRL1 overcomes imatinib resistance in chronic myelogenous leukemia-derived cell lines via the production of tumor necrosis factor-related apoptosis-inducing ligand. Cancer Sci 98:1949-1958.
    • (2007) Cancer Sci , vol.98 , pp. 1949-1958
    • Kikuchi, S.1    Nagai, T.2    Kunitama, M.3    Kirito, K.4    Ozawa, K.5    Komatsu, N.6
  • 53
    • 0036894711 scopus 로고    scopus 로고
    • ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR
    • Kullmann M, Gopfert U, Siewe B, Hengst L. 2002. ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR. Genes Dev 16:3087-3099.
    • (2002) Genes Dev , vol.16 , pp. 3087-3099
    • Kullmann, M.1    Gopfert, U.2    Siewe, B.3    Hengst, L.4
  • 57
    • 0030791974 scopus 로고    scopus 로고
    • Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL
    • Lavau C, Szilvassy SJ, Slany R, Cleary ML. 1997. Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL. EMBO J 16:4226-4237.
    • (1997) EMBO J , vol.16 , pp. 4226-4237
    • Lavau, C.1    Szilvassy, S.J.2    Slany, R.3    Cleary, M.L.4
  • 58
    • 0032012062 scopus 로고    scopus 로고
    • Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade
    • Levkau B, Koyama H, Raines EW, Clurman BE, Herren B, Orth K, Roberts JM, Ross R. 1998. Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade. Mol Cell 1:553-563.
    • (1998) Mol Cell , vol.1 , pp. 553-563
    • Levkau, B.1    Koyama, H.2    Raines, E.W.3    Clurman, B.E.4    Herren, B.5    Orth, K.6    Roberts, J.M.7    Ross, R.8
  • 62
    • 77954152739 scopus 로고    scopus 로고
    • Ubiquitylation and proteasomal degradation of the p21(Cip1), p27(Kip1) and p57(Kip2) CDK inhibitors
    • Lu Z, Hunter T. 2010. Ubiquitylation and proteasomal degradation of the p21(Cip1), p27(Kip1) and p57(Kip2) CDK inhibitors. Cell Cycle 9:2342-2352.
    • (2010) Cell Cycle , vol.9 , pp. 2342-2352
    • Lu, Z.1    Hunter, T.2
  • 66
    • 0037216528 scopus 로고    scopus 로고
    • Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions
    • McAllister SS, Becker-Hapak M, Pintucci G, Pagano M, Dowdy SF. 2003. Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions. Mol Cell Biol 23:216-228.
    • (2003) Mol Cell Biol , vol.23 , pp. 216-228
    • McAllister, S.S.1    Becker-Hapak, M.2    Pintucci, G.3    Pagano, M.4    Dowdy, S.F.5
  • 67
    • 0034643331 scopus 로고    scopus 로고
    • AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
    • Medema RH, Kops GJ, Bos JL, Burgering BM. 2000. AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature 404:782-787.
    • (2000) Nature , vol.404 , pp. 782-787
    • Medema, R.H.1    Kops, G.J.2    Bos, J.L.3    Burgering, B.M.4
  • 68
    • 15144357686 scopus 로고    scopus 로고
    • Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest
    • Millard SS, Yan JS, Nguyen H, Pagano M, Kiyokawa H, Koff A. 1997. Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest. J Biol Chem 272:7093-7098.
    • (1997) J Biol Chem , vol.272 , pp. 7093-7098
    • Millard, S.S.1    Yan, J.S.2    Nguyen, H.3    Pagano, M.4    Kiyokawa, H.5    Koff, A.6
  • 70
    • 3442890875 scopus 로고    scopus 로고
    • Cytoplasmic mislocalization of p27Kip1 protein is associated with constitutive phosphorylation of Akt or protein kinase B and poor prognosis in acute myelogenous leukemia
    • Min YH, Cheong JW, Kim JY, Eom JI, Lee ST, Hahn JS, Ko YW, Lee MH. 2004. Cytoplasmic mislocalization of p27Kip1 protein is associated with constitutive phosphorylation of Akt or protein kinase B and poor prognosis in acute myelogenous leukemia. Cancer Res 64:5225-5231.
    • (2004) Cancer Res , vol.64 , pp. 5225-5231
    • Min, Y.H.1    Cheong, J.W.2    Kim, J.Y.3    Eom, J.I.4    Lee, S.T.5    Hahn, J.S.6    Ko, Y.W.7    Lee, M.H.8
  • 72
    • 0034947868 scopus 로고    scopus 로고
    • Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation
    • Miskimins WK, Wang G, Hawkinson M, Miskimins R. 2001. Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation. Mol Cell Biol 21:4960-4967.
    • (2001) Mol Cell Biol , vol.21 , pp. 4960-4967
    • Miskimins, W.K.1    Wang, G.2    Hawkinson, M.3    Miskimins, R.4
  • 73
    • 0031418659 scopus 로고    scopus 로고
    • Stable overexpression of PML alters regulation of cell cycle progression in HeLa cells
    • Mu ZM, Le XF Vallian, Glassman AB, Chang KS. 1997. Stable overexpression of PML alters regulation of cell cycle progression in HeLa cells. Carcinogenesis 18:2063-2069.
    • (1997) Carcinogenesis , vol.18 , pp. 2063-2069
    • Mu, Z.M.1    Le, V.2    Glassman, A.B.3    Chang, K.S.4
  • 74
    • 34248401210 scopus 로고    scopus 로고
    • Akt1 sequentially phosphorylates p27kip1 within a conserved but non-canonical region
    • Nacusi LP, Sheaff RJ. 2006. Akt1 sequentially phosphorylates p27kip1 within a conserved but non-canonical region. Cell Div 1:11.
    • (2006) Cell Div , vol.1 , pp. 11
    • Nacusi, L.P.1    Sheaff, R.J.2
  • 77
    • 27944481670 scopus 로고    scopus 로고
    • The cell cycle regulator p27Kip1 interacts with MCM7, a DNA replication licensing factor, to inhibit initiation of DNA replication
    • Nallamshetty S, Crook M, Boehm M, Yoshimoto T, Olive M, Nabel EG. 2005. The cell cycle regulator p27Kip1 interacts with MCM7, a DNA replication licensing factor, to inhibit initiation of DNA replication. FEBS Lett 579:6529-6536.
    • (2005) FEBS Lett , vol.579 , pp. 6529-6536
    • Nallamshetty, S.1    Crook, M.2    Boehm, M.3    Yoshimoto, T.4    Olive, M.5    Nabel, E.G.6
  • 79
    • 84867415951 scopus 로고    scopus 로고
    • Probing the role of nascent helicity in p27 function as a cell cycle regulator
    • Otieno S, Kriwacki R. 2012. Probing the role of nascent helicity in p27 function as a cell cycle regulator. PLoS ONE 7:e47177.
    • (2012) PLoS ONE , vol.7 , pp. e47177
    • Otieno, S.1    Kriwacki, R.2
  • 80
    • 80051927358 scopus 로고    scopus 로고
    • Incomplete folding upon binding mediates Cdk4/cyclin D complex activation by tyrosine phosphorylation of inhibitor p27 protein
    • Ou L, Ferreira AM, Otieno S, Xiao L, Bashford D, Kriwacki RW. 2011. Incomplete folding upon binding mediates Cdk4/cyclin D complex activation by tyrosine phosphorylation of inhibitor p27 protein. J Biol Chem 286:30142-30151.
    • (2011) J Biol Chem , vol.286 , pp. 30142-30151
    • Ou, L.1    Ferreira, A.M.2    Otieno, S.3    Xiao, L.4    Bashford, D.5    Kriwacki, R.W.6
  • 84
    • 0033214995 scopus 로고    scopus 로고
    • Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1)
    • Perez-Roger I, Kim SH, Griffiths B, Sewing A, Land H. 1999. Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1). EMBO J 18:5310-5320.
    • (1999) EMBO J , vol.18 , pp. 5310-5320
    • Perez-Roger, I.1    Kim, S.H.2    Griffiths, B.3    Sewing, A.4    Land, H.5
  • 86
    • 0028179669 scopus 로고
    • P27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
    • Polyak K, Kato JY, Solomon MJ, Sherr CJ, Massague J, Roberts JM, Koff A. 1994a. P27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. Genes Dev 8:9-22.
    • (1994) Genes Dev , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.Y.2    Solomon, M.J.3    Sherr, C.J.4    Massague, J.5    Roberts, J.M.6    Koff, A.7
  • 87
    • 0028176483 scopus 로고
    • Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
    • Polyak K, Lee MH, Erdjument-Bromage H, Koff A, Roberts JM, Tempst P, Massague J. 1994b. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78:59-66.
    • (1994) Cell , vol.78 , pp. 59-66
    • Polyak, K.1    Lee, M.H.2    Erdjument-Bromage, H.3    Koff, A.4    Roberts, J.M.5    Tempst, P.6    Massague, J.7
  • 90
    • 0035803593 scopus 로고    scopus 로고
    • P27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis
    • Rodier G, Montagnoli A, Di Marcotullio L, Coulombe P, Draetta GF, Pagano M, Meloche S. 2001. P27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis. EMBO J 20:6672-6682.
    • (2001) EMBO J , vol.20 , pp. 6672-6682
    • Rodier, G.1    Montagnoli, A.2    Di Marcotullio, L.3    Coulombe, P.4    Draetta, G.F.5    Pagano, M.6    Meloche, S.7
  • 92
    • 84885056560 scopus 로고    scopus 로고
    • Increased cytoplasmic localization of p27(kip1) and its modulation of RhoA activity during progression of chronic myeloid leukemia
    • Roy A, Lahiry L, Banerjee D, Ghosh M, Banerjee S. 2013. Increased cytoplasmic localization of p27(kip1) and its modulation of RhoA activity during progression of chronic myeloid leukemia. PLoS ONE 8:e76527.
    • (2013) PLoS ONE , vol.8 , pp. e76527
    • Roy, A.1    Lahiry, L.2    Banerjee, D.3    Ghosh, M.4    Banerjee, S.5
  • 93
    • 0029665852 scopus 로고    scopus 로고
    • Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex
    • Russo AA, Jeffrey PD, Patten AK, Massague J, Pavletich NP. 1996. Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature 382:325-331.
    • (1996) Nature , vol.382 , pp. 325-331
    • Russo, A.A.1    Jeffrey, P.D.2    Patten, A.K.3    Massague, J.4    Pavletich, N.P.5
  • 96
    • 85006602738 scopus 로고    scopus 로고
    • Suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)
    • Sekimoto T, Fukumoto M, Yoneda Y. 2004. Suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1). EMBO J 23:14-13.
    • (2004) EMBO J , vol.23 , pp. 13-14
    • Sekimoto, T.1    Fukumoto, M.2    Yoneda, Y.3
  • 97
    • 36349001697 scopus 로고    scopus 로고
    • Pleiotropic p27(Kip1), BCR-ABL and leukemic stem cell: the trio in concert
    • Sengupta A, Banerjee S. 2007. Pleiotropic p27(Kip1), BCR-ABL and leukemic stem cell: the trio in concert. Leukemia 21:2559-2561.
    • (2007) Leukemia , vol.21 , pp. 2559-2561
    • Sengupta, A.1    Banerjee, S.2
  • 99
    • 33645802169 scopus 로고    scopus 로고
    • Cyclin-dependent kinase pathways as targets for cancer treatment
    • Shapiro GI. 2006. Cyclin-dependent kinase pathways as targets for cancer treatment. J Clin Oncol 24:1770-1783.
    • (2006) J Clin Oncol , vol.24 , pp. 1770-1783
    • Shapiro, G.I.1
  • 101
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: positive and negative regulators of G1-phase progression
    • Sherr CJ, Roberts JM. 1999. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 13:1501-1512.
    • (1999) Genes Dev , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 102
    • 0036799377 scopus 로고    scopus 로고
    • PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization
    • Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL. 2002. PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. Nat Med 8:1145-1152.
    • (2002) Nat Med , vol.8 , pp. 1145-1152
    • Shin, I.1    Yakes, F.M.2    Rojo, F.3    Shin, N.Y.4    Bakin, A.V.5    Baselga, J.6    Arteaga, C.L.7
  • 105
    • 0037094096 scopus 로고    scopus 로고
    • The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2
    • Stahl M, Dijkers PF, Kops GJ, Lens SM, Coffer PJ, Burgering BM, Medema RH. 2002. The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2. J Immunol 168:5024-5031.
    • (2002) J Immunol , vol.168 , pp. 5024-5031
    • Stahl, M.1    Dijkers, P.F.2    Kops, G.J.3    Lens, S.M.4    Coffer, P.J.5    Burgering, B.M.6    Medema, R.H.7
  • 106
    • 84855321395 scopus 로고    scopus 로고
    • Multiple degradation pathways regulate versatile CIP/KIP CDK inhibitors
    • Starostina NG, Kipreos ET. 2012. Multiple degradation pathways regulate versatile CIP/KIP CDK inhibitors. Trends Cell Biol 22:33-41.
    • (2012) Trends Cell Biol , vol.22 , pp. 33-41
    • Starostina, N.G.1    Kipreos, E.T.2
  • 107
    • 0029927496 scopus 로고    scopus 로고
    • Mutational analysis of the candidate tumor suppressor genes TEL and KIP1 in childhood acute lymphoblastic leukemia
    • Stegmaier K, Takeuchi S, Golub TR, Bohlander SK, Bartram CR, Koeffler HP. 1996. Mutational analysis of the candidate tumor suppressor genes TEL and KIP1 in childhood acute lymphoblastic leukemia. Cancer Res 56:1413-1417.
    • (1996) Cancer Res , vol.56 , pp. 1413-1417
    • Stegmaier, K.1    Takeuchi, S.2    Golub, T.R.3    Bohlander, S.K.4    Bartram, C.R.5    Koeffler, H.P.6
  • 108
    • 0035853813 scopus 로고    scopus 로고
    • Direct binding of the signal-transducing adaptor Grb2 facilitates down-regulation of the cyclin-dependent kinase inhibitor p27Kip1
    • Sugiyama Y, Tomoda K, Tanaka T, Arata Y, Yoneda-Kato N, Kato J. 2001. Direct binding of the signal-transducing adaptor Grb2 facilitates down-regulation of the cyclin-dependent kinase inhibitor p27Kip1. J Biol Chem 276:12084-12090.
    • (2001) J Biol Chem , vol.276 , pp. 12084-12090
    • Sugiyama, Y.1    Tomoda, K.2    Tanaka, T.3    Arata, Y.4    Yoneda-Kato, N.5    Kato, J.6
  • 110
    • 11244272124 scopus 로고    scopus 로고
    • The Jab1/COP9 signalosome subcomplex is a downstream mediator of Bcr-Abl kinase activity and facilitates cell-cycle progression
    • Tomoda K, Kato JY, Tatsumi E, Takahashi T, Matsuo Y, Yoneda-Kato N. 2005. The Jab1/COP9 signalosome subcomplex is a downstream mediator of Bcr-Abl kinase activity and facilitates cell-cycle progression. Blood 105:775-783.
    • (2005) Blood , vol.105 , pp. 775-783
    • Tomoda, K.1    Kato, J.Y.2    Tatsumi, E.3    Takahashi, T.4    Matsuo, Y.5    Yoneda-Kato, N.6
  • 111
    • 0033545636 scopus 로고    scopus 로고
    • Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
    • Tomoda K, Kubota Y, Kato J. 1999. Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1. Nature 398:160-165.
    • (1999) Nature , vol.398 , pp. 160-165
    • Tomoda, K.1    Kubota, Y.2    Kato, J.3
  • 112
    • 0028363519 scopus 로고
    • P27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
    • Toyoshima H, Hunter T. 1994. P27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78:67-74.
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 113
    • 14844333094 scopus 로고    scopus 로고
    • Global effects of BCR/ABL and TEL/PDGFRbeta expression on the proteome and phosphoproteome: identification of the Rho pathway as a target of BCR/ABL
    • Unwin RD, Sternberg DW, Lu Y, Pierce A, Gilliland DG, Whetton AD. 2005. Global effects of BCR/ABL and TEL/PDGFRbeta expression on the proteome and phosphoproteome: identification of the Rho pathway as a target of BCR/ABL. J Biol Chem 280:6316-6326.
    • (2005) J Biol Chem , vol.280 , pp. 6316-6326
    • Unwin, R.D.1    Sternberg, D.W.2    Lu, Y.3    Pierce, A.4    Gilliland, D.G.5    Whetton, A.D.6
  • 114
    • 0037053407 scopus 로고    scopus 로고
    • Rho activity can alter the translation of p27 mRNA and is important for RasV12-induced transformation in a manner dependent on p27 status
    • Vidal A, Millard SS, Miller JP, Koff A. 2002. Rho activity can alter the translation of p27 mRNA and is important for RasV12-induced transformation in a manner dependent on p27 status. J Biol Chem 277:16433-16440.
    • (2002) J Biol Chem , vol.277 , pp. 16433-16440
    • Vidal, A.1    Millard, S.S.2    Miller, J.P.3    Koff, A.4
  • 116
    • 0030847760 scopus 로고    scopus 로고
    • Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27
    • Vlach J, Hennecke S, Amati B. 1997. Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27. EMBO J 16:5334-5344.
    • (1997) EMBO J , vol.16 , pp. 5334-5344
    • Vlach, J.1    Hennecke, S.2    Amati, B.3
  • 121
    • 0037046491 scopus 로고    scopus 로고
    • BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1)
    • Williamson EA, Dadmanesh F, Koeffler HP. 2002. BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1). Oncogene 21:3199-3206.
    • (2002) Oncogene , vol.21 , pp. 3199-3206
    • Williamson, E.A.1    Dadmanesh, F.2    Koeffler, H.P.3
  • 122
    • 33644509197 scopus 로고    scopus 로고
    • Reduction of cytosolic p27(Kip1) inhibits cancer cell motility, survival, and tumorigenicity
    • Wu FY, Wang SE, Sanders ME, Shin I, Rojo F, Baselga J, Arteaga CL. 2006. Reduction of cytosolic p27(Kip1) inhibits cancer cell motility, survival, and tumorigenicity. Cancer Res 66:2162-2172.
    • (2006) Cancer Res , vol.66 , pp. 2162-2172
    • Wu, F.Y.1    Wang, S.E.2    Sanders, M.E.3    Shin, I.4    Rojo, F.5    Baselga, J.6    Arteaga, C.L.7
  • 125
    • 80051934411 scopus 로고    scopus 로고
    • Bcr-Abl oncogene stimulates Jab1 expression via cooperative interaction of beta-catenin and STAT1 in chronic myeloid leukemia cells
    • Yang KT, Wang MC, Chen JY, Hsu MC, Hung WC. 2011. Bcr-Abl oncogene stimulates Jab1 expression via cooperative interaction of beta-catenin and STAT1 in chronic myeloid leukemia cells. J Cell Physiol 226:2849-2856.
    • (2011) J Cell Physiol , vol.226 , pp. 2849-2856
    • Yang, K.T.1    Wang, M.C.2    Chen, J.Y.3    Hsu, M.C.4    Hung, W.C.5
  • 126
    • 84873201989 scopus 로고    scopus 로고
    • VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells
    • Yu CC, Yang JC, Chang YC, Chuang JG, Lin CW, Wu MS, Chow LP. 2013. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. PLoS ONE 8:e55724.
    • (2013) PLoS ONE , vol.8 , pp. e55724
    • Yu, C.C.1    Yang, J.C.2    Chang, Y.C.3    Chuang, J.G.4    Lin, C.W.5    Wu, M.S.6    Chow, L.P.7
  • 130
    • 0035871781 scopus 로고    scopus 로고
    • A model of human p210(bcr/ABL)-mediated chronic myelogenous leukemia by transduction of primary normal human CD34(+) cells with a BCR/ABL-containing retroviral vector
    • Zhao RC, Jiang Y, Verfaillie CM. 2001. A model of human p210(bcr/ABL)-mediated chronic myelogenous leukemia by transduction of primary normal human CD34(+) cells with a BCR/ABL-containing retroviral vector. Blood 97:2406-2412.
    • (2001) Blood , vol.97 , pp. 2406-2412
    • Zhao, R.C.1    Jiang, Y.2    Verfaillie, C.M.3
  • 132
    • 69949134410 scopus 로고    scopus 로고
    • Pin1 catalyzes conformational changes of Thr-187 in p27Kip1 and mediates its stability through a polyubiquitination process
    • Zhou W, Yang Q, Low CB, Karthik BC, Wang Y, Ryo A, Yao SQ, Yang D, Liou YC. 2009. Pin1 catalyzes conformational changes of Thr-187 in p27Kip1 and mediates its stability through a polyubiquitination process. J Biol Chem 284:23980-23988.
    • (2009) J Biol Chem , vol.284 , pp. 23980-23988
    • Zhou, W.1    Yang, Q.2    Low, C.B.3    Karthik, B.C.4    Wang, Y.5    Ryo, A.6    Yao, S.Q.7    Yang, D.8    Liou, Y.C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.