메뉴 건너뛰기




Volumn 105, Issue 2, 2005, Pages 775-783

The Jab1/COP9 signalosome subcomplex is a downstream mediator of Bcr-Abl kinase activity and facilitates cell-cycle progression

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; COP9 SIGNALOSOME; CYCLIN DEPENDENT KINASE INHIBITOR 1B; IMATINIB; JAB 1 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN KINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 11244272124     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-04-1242     Document Type: Article
Times cited : (64)

References (53)
  • 1
    • 0023410428 scopus 로고
    • In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome
    • McLaughlin J, Chianese E, Witte ON. In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome. Proc Natl Acad Sci USA. 1987;84:6558-6562.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 6558-6562
    • McLaughlin, J.1    Chianese, E.2    Witte, O.N.3
  • 2
    • 0026608119 scopus 로고
    • Initiation of deregulated growth of multipotent progenitor cells by bcr-abl in vitro
    • Gishizky ML, Witte ON. Initiation of deregulated growth of multipotent progenitor cells by bcr-abl in vitro. Science. 1992;256:836-839.
    • (1992) Science , vol.256 , pp. 836-839
    • Gishizky, M.L.1    Witte, O.N.2
  • 3
    • 0033614446 scopus 로고    scopus 로고
    • Chronic myeloid leukemia
    • Sawyers CL. Chronic myeloid leukemia. N Engl J Med. 1999;340:1330-1340.
    • (1999) N Engl J Med , vol.340 , pp. 1330-1340
    • Sawyers, C.L.1
  • 4
    • 0033603435 scopus 로고    scopus 로고
    • Signaling pathways activated by oncogenic forms of Abl tyrosine kinase
    • Zou X, Calame K. Signaling pathways activated by oncogenic forms of Abl tyrosine kinase. J Biol Chem. 1999;274:18141-18144.
    • (1999) J Biol Chem , vol.274 , pp. 18141-18144
    • Zou, X.1    Calame, K.2
  • 5
    • 0035839842 scopus 로고    scopus 로고
    • Modeling Philadelphia chromosome positive leukemias
    • Wong S, Witte ON. Modeling Philadelphia chromosome positive leukemias. Oncogene. 2001;20: 5644-5659.
    • (2001) Oncogene , vol.20 , pp. 5644-5659
    • Wong, S.1    Witte, O.N.2
  • 6
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ. Cancer cell cycles. Science. 1996;274: 1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 7
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr CJ, Roberts JM. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 1999;13:1501-1512.
    • (1999) Genes Dev , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 8
    • 0031048716 scopus 로고    scopus 로고
    • Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
    • Porter PL, Malone KE, Heagerty PJ, et al. Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nat Med. 1997;3:222-225.
    • (1997) Nat Med , vol.3 , pp. 222-225
    • Porter, P.L.1    Malone, K.E.2    Heagerty, P.J.3
  • 9
    • 16944363001 scopus 로고    scopus 로고
    • Decreased levels of the cell-cycle inhibitor p27Kip1 protein: Prognostic implications in primary breast cancer
    • Catzavelos C, Bhattacharya N, Ung YC, et al. Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer. Nat Med. 1997;3:227-230.
    • (1997) Nat Med , vol.3 , pp. 227-230
    • Catzavelos, C.1    Bhattacharya, N.2    Ung, Y.C.3
  • 10
    • 0031048236 scopus 로고    scopus 로고
    • Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
    • Loda M, Cukor B, Tam SW, et al. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat Med. 1997;3:231-234.
    • (1997) Nat Med , vol.3 , pp. 231-234
    • Loda, M.1    Cukor, B.2    Tam, S.W.3
  • 11
  • 12
    • 0036733716 scopus 로고    scopus 로고
    • Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer
    • Signoretti S, Di Marcotullio L, Richardson A, et al. Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer. J Clin Invest. 2002; 110:633-641.
    • (2002) J Clin Invest , vol.110 , pp. 633-641
    • Signoretti, S.1    Di Marcotullio, L.2    Richardson, A.3
  • 13
    • 18644370396 scopus 로고    scopus 로고
    • Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer
    • Viglietto G, Motti ML, Bruni R et al. Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer. Nat Med. 2002;8:1136-1144.
    • (2002) Nat Med , vol.8 , pp. 1136-1144
    • Viglietto, G.1    Motti, M.L.2    Bruni, R.3
  • 14
    • 0036799377 scopus 로고    scopus 로고
    • PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization
    • Shin I, Yakes FM, Rojo F, et al. PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. Nat Med. 2002;8:1145-1152.
    • (2002) Nat Med , vol.8 , pp. 1145-1152
    • Shin, I.1    Yakes, F.M.2    Rojo, F.3
  • 15
    • 18644376449 scopus 로고    scopus 로고
    • PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest
    • Liang J, Zubovitz J, Petracelli T, et al. PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest. Nat Med. 2002;8:1153-1160.
    • (2002) Nat Med , vol.8 , pp. 1153-1160
    • Liang, J.1    Zubovitz, J.2    Petracelli, T.3
  • 16
    • 0034283987 scopus 로고    scopus 로고
    • Bcr-Abl kinase down-regulates cyclin-dependent kinase inhibitor p27 in human and murine cell lines
    • Jonuleit T, van der Kuip H, Miething C, et al. Bcr-Abl kinase down-regulates cyclin-dependent kinase inhibitor p27 in human and murine cell lines. Blood. 2000;96:1933-1939.
    • (2000) Blood , vol.96 , pp. 1933-1939
    • Jonuleit, T.1    Van Der Kuip, H.2    Miething, C.3
  • 17
    • 0034671745 scopus 로고    scopus 로고
    • BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway
    • Gesbert F, Sellers WR, Signoretti S, Loda M, Griffin JD. BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway. J Biol Chem. 2000;275:39223- 39230.
    • (2000) J Biol Chem , vol.275 , pp. 39223-39230
    • Gesbert, F.1    Sellers, W.R.2    Signoretti, S.3    Loda, M.4    Griffin, J.D.5
  • 18
    • 10744220576 scopus 로고    scopus 로고
    • BCR-ABL and interleukin 3 promote haematopoietic cell proliferation and survival through modulation of cyclin D2 and p27Kip1 expression
    • Parada Y, Banerji L, Glassford J, et al. BCR-ABL and interleukin 3 promote haematopoietic cell proliferation and survival through modulation of cyclin D2 and p27Kip1 expression. J Biol Chem. 2001;276:23572-23580.
    • (2001) J Biol Chem , vol.276 , pp. 23572-23580
    • Parada, Y.1    Banerji, L.2    Glassford, J.3
  • 19
    • 0034641709 scopus 로고    scopus 로고
    • Abnormal integrin-mediated regulation of chronic myelogenous leukemia CD34+ cell proliferation: BCR/ABL up-regulates the cyclin-dependent kinase inhibitor, p27Kip, which is relocated to the cell cytoplasm and incapable of regulating cdk2 activity
    • Jiang Y, Zhao RC, Verfaillie CM. Abnormal integrin-mediated regulation of chronic myelogenous leukemia CD34+ cell proliferation: BCR/ABL up-regulates the cyclin-dependent kinase inhibitor, p27Kip, which is relocated to the cell cytoplasm and incapable of regulating cdk2 activity. Proc Natl Acad Sci USA. 2000;97:10538-10543.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10538-10543
    • Jiang, Y.1    Zhao, R.C.2    Verfaillie, C.M.3
  • 20
    • 0033545636 scopus 로고    scopus 로고
    • Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab 1
    • Tomoda K, Kubota Y, Kato J. Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab 1. Nature. 1999;398:160-165.
    • (1999) Nature , vol.398 , pp. 160-165
    • Tomoda, K.1    Kubota, Y.2    Kato, J.3
  • 21
    • 0031921216 scopus 로고    scopus 로고
    • A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits
    • Seeger M, Kraft R, Ferrell K, et al. A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits. FASEB J. 1998;12:469-478.
    • (1998) FASEB J , vol.12 , pp. 469-478
    • Seeger, M.1    Kraft, R.2    Ferrell, K.3
  • 22
    • 0032993486 scopus 로고    scopus 로고
    • Making sense of the COP9 signalosome: A regulatory protein complex conserved from Arabidopsis to human
    • Wei N, Deng XW. Making sense of the COP9 signalosome: a regulatory protein complex conserved from Arabidopsis to human. Trends Genet. 1999;15:98-103.
    • (1999) Trends Genet , vol.15 , pp. 98-103
    • Wei, N.1    Deng, X.W.2
  • 23
    • 0033544866 scopus 로고    scopus 로고
    • COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK
    • Naumann M, Bech-Otschir D, Huang X, Ferrell K, Dubiel W. COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK. J Biol Chem. 1999;274:35297-35300.
    • (1999) J Biol Chem , vol.274 , pp. 35297-35300
    • Naumann, M.1    Bech-Otschir, D.2    Huang, X.3    Ferrell, K.4    Dubiel, W.5
  • 24
    • 0034671924 scopus 로고    scopus 로고
    • Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15): A possible link between interferon regulatory factor signaling and the COP9/signalosome
    • Cohen H, Azriel A, Cohen T, et al. Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15): a possible link between interferon regulatory factor signaling and the COP9/signalosome. J Biol Chem. 2000;275:39081-39089.
    • (2000) J Biol Chem , vol.275 , pp. 39081-39089
    • Cohen, H.1    Azriel, A.2    Cohen, T.3
  • 25
    • 0036472506 scopus 로고    scopus 로고
    • The COP9 signalosome: At the interface between signal transduction and ubiquitin-dependent proteolysis
    • Bech-Otschir D, Seeger M, Dubiel W. The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis. J Cell Sci. 2002;115:467-473.
    • (2002) J Cell Sci , vol.115 , pp. 467-473
    • Bech-Otschir, D.1    Seeger, M.2    Dubiel, W.3
  • 26
    • 0035794541 scopus 로고    scopus 로고
    • COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system
    • Bech-Otschir D, Kraft R, Huang X, et al. COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system. EMBO J. 2001;20:1630-1639.
    • (2001) EMBO J , vol.20 , pp. 1630-1639
    • Bech-Otschir, D.1    Kraft, R.2    Huang, X.3
  • 27
    • 0035906430 scopus 로고    scopus 로고
    • Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome
    • Lyapina S, Cope G, Shevchenko A, et al. Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science. 2001;292:1382-1385.
    • (2001) Science , vol.292 , pp. 1382-1385
    • Lyapina, S.1    Cope, G.2    Shevchenko, A.3
  • 28
    • 0037131242 scopus 로고    scopus 로고
    • Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1
    • Cope GA, Suh GS, Aravind L, et al. Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science. 2002; 298:608-611.
    • (2002) Science , vol.298 , pp. 608-611
    • Cope, G.A.1    Suh, G.S.2    Aravind, L.3
  • 29
    • 0032203713 scopus 로고    scopus 로고
    • Arabidopsis homologs of a c-Jun coactivator are present both in monomeric form and in the COP9 complex, and their abundance is differentially affected by the pleiotropic cop/det/fus notations
    • Kwok SF, Solano R, Tsuge T, et al. Arabidopsis homologs of a c-Jun coactivator are present both in monomeric form and in the COP9 complex, and their abundance is differentially affected by the pleiotropic cop/det/fus notations. Plant Cell. 1998;10:1779-1790.
    • (1998) Plant Cell , vol.10 , pp. 1779-1790
    • Kwok, S.F.1    Solano, R.2    Tsuge, T.3
  • 30
    • 0036800232 scopus 로고    scopus 로고
    • COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster
    • Oron E, Mannervik M, Rencus S, et al. COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster. Development. 2002;129:4399-4409.
    • (2002) Development , vol.129 , pp. 4399-4409
    • Oron, E.1    Mannervik, M.2    Rencus, S.3
  • 31
    • 0033592537 scopus 로고    scopus 로고
    • The COP9 signalosome is essential for development of Drosophila melanogaster
    • Freilich S, Oron E, Kapp Y, et al. The COP9 signalosome is essential for development of Drosophila melanogaster. Curr Biol. 1999;9:1187-1190.
    • (1999) Curr Biol , vol.9 , pp. 1187-1190
    • Freilich, S.1    Oron, E.2    Kapp, Y.3
  • 32
    • 0037127256 scopus 로고    scopus 로고
    • The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex
    • Tomoda K, Kubota Y, Arata Y, et al. The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex. J Biol Chem. 2002;277: 2302-2310.
    • (2002) J Biol Chem , vol.277 , pp. 2302-2310
    • Tomoda, K.1    Kubota, Y.2    Arata, Y.3
  • 33
    • 0037117417 scopus 로고    scopus 로고
    • The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1
    • Yang X, Menon S, Lykke-Andersen K, et al. The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1. Curr Biol. 2002;12: 667-672.
    • (2002) Curr Biol , vol.12 , pp. 667-672
    • Yang, X.1    Menon, S.2    Lykke-Andersen, K.3
  • 34
    • 0032525270 scopus 로고    scopus 로고
    • Secondary mutation maintains the transformed state in BaF3 cells with inducible BCR/ABL expression
    • Klucher KM, Lopez DV, Daley GQ. Secondary mutation maintains the transformed state in BaF3 cells with inducible BCR/ABL expression. Blood. 1998;91:3927-3934.
    • (1998) Blood , vol.91 , pp. 3927-3934
    • Klucher, K.M.1    Lopez, D.V.2    Daley, G.Q.3
  • 35
    • 18544372618 scopus 로고    scopus 로고
    • Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells
    • Sonoyama J, Matsumura I, Ezoe S, et al. Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells. J Biol Chem. 2002;277:8076-8082.
    • (2002) J Biol Chem , vol.277 , pp. 8076-8082
    • Sonoyama, J.1    Matsumura, I.2    Ezoe, S.3
  • 36
    • 0037081203 scopus 로고    scopus 로고
    • Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells
    • Jena N, Deng M, Sicinska E, Sicinski P, Daley GQ. Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells. Cancer Res. 2002;62:535-541.
    • (2002) Cancer Res , vol.62 , pp. 535-541
    • Jena, N.1    Deng, M.2    Sicinska, E.3    Sicinski, P.4    Daley, G.Q.5
  • 37
    • 0037222235 scopus 로고    scopus 로고
    • Imatinib mesylate therapy in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia: High incidence of early complete and major cytogenetic responses
    • Kantarjian HM, Cortes JE, O'Brien S, et al. Imatinib mesylate therapy in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia: high incidence of early complete and major cytogenetic responses. Blood. 2003;101:97-100.
    • (2003) Blood , vol.101 , pp. 97-100
    • Kantarjian, H.M.1    Cortes, J.E.2    O'Brien, S.3
  • 38
    • 0033119211 scopus 로고    scopus 로고
    • Comparison of human COP9 signalsome and 26S proteasome lid
    • Henke W, Ferrell K, Bech-Otschir D, et al. Comparison of human COP9 signalsome and 26S proteasome lid. Mol Biol Rep. 1999;26:29-34.
    • (1999) Mol Biol Rep , vol.26 , pp. 29-34
    • Henke, W.1    Ferrell, K.2    Bech-Otschir, D.3
  • 39
    • 0034092911 scopus 로고    scopus 로고
    • Regulation of the cdk inhibitor p27 and its deregulation in cancer
    • Slingerland J, Pagano M. Regulation of the cdk inhibitor p27 and its deregulation in cancer. J Cell Physiol. 2000;183:10-17.
    • (2000) J Cell Physiol , vol.183 , pp. 10-17
    • Slingerland, J.1    Pagano, M.2
  • 41
    • 0029024015 scopus 로고
    • Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
    • Pagano M, Tam SW, Theodoras AM, et al. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science. 1995;269:682-685.
    • (1995) Science , vol.269 , pp. 682-685
    • Pagano, M.1    Tam, S.W.2    Theodoras, A.M.3
  • 43
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer. 2002;2:489-501.
    • (2002) Nat Rev Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 44
    • 0034637527 scopus 로고    scopus 로고
    • Onco signals of HER-2/neu in regulating the stability of the cyclin-dependent kinase inhibitor p27
    • Yang HY, Zhou BP, Hung MC, Lee MH. Onco signals of HER-2/neu in regulating the stability of the cyclin-dependent kinase inhibitor p27. J Biol Chem. 2000;275:24735-24739.
    • (2000) J Biol Chem , vol.275 , pp. 24735-24739
    • Yang, H.Y.1    Zhou, B.P.2    Hung, M.C.3    Lee, M.H.4
  • 45
    • 0029761277 scopus 로고    scopus 로고
    • A new group of conserved coactivators that increase the specificity of AP-1 transcription factors
    • Claret FX, Hibi M, Dhut S, Toda T, Karin M. A new group of conserved coactivators that increase the specificity of AP-1 transcription factors. Nature. 1996;383:453-457.
    • (1996) Nature , vol.383 , pp. 453-457
    • Claret, F.X.1    Hibi, M.2    Dhut, S.3    Toda, T.4    Karin, M.5
  • 46
    • 0033519690 scopus 로고    scopus 로고
    • The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators
    • Dechend R, Hirano F, Lehmann K, et al. The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators. Oncogene. 1999;18:3316-3323.
    • (1999) Oncogene , vol.18 , pp. 3316-3323
    • Dechend, R.1    Hirano, F.2    Lehmann, K.3
  • 47
    • 0037016769 scopus 로고    scopus 로고
    • Jab1 interacts directly with HIF-1alpha and regulates its stability
    • Bae MK, Ahn MY, Jeong JW, et al. Jab1 interacts directly with HIF-1alpha and regulates its stability. J Biol Chem. 2002;277:9-12.
    • (2002) J Biol Chem , vol.277 , pp. 9-12
    • Bae, M.K.1    Ahn, M.Y.2    Jeong, J.W.3
  • 48
    • 0035675964 scopus 로고    scopus 로고
    • Jab1 expression is associated with inverse expression of p27(kip1) and poor prognosis in epithelial ovarian tumors
    • Sui L, Dong Y, Ohno M, et al. Jab1 expression is associated with inverse expression of p27(kip1) and poor prognosis in epithelial ovarian tumors. Clin Cancer Res. 2001;7:4130-4135.
    • (2001) Clin Cancer Res , vol.7 , pp. 4130-4135
    • Sui, L.1    Dong, Y.2    Ohno, M.3
  • 49
    • 0037567489 scopus 로고    scopus 로고
    • Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1)
    • Kouvaraki MA, Rassidakis GZ, Tian L, Kumar R, Kittas C, Claret FX. Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1). Cancer Res. 2003;63:2977-2981.
    • (2003) Cancer Res , vol.63 , pp. 2977-2981
    • Kouvaraki, M.A.1    Rassidakis, G.Z.2    Tian, L.3    Kumar, R.4    Kittas, C.5    Claret, F.X.6
  • 50
    • 0037343089 scopus 로고    scopus 로고
    • Expression of p27(Kip1) and c-Jun activation binding protein 1 are inversely correlated in systemic anaplastic large cell lymphoma
    • Rassidakis GZ, Claret FX, Lai R, et al. Expression of p27(Kip1) and c-Jun activation binding protein 1 are inversely correlated in systemic anaplastic large cell lymphoma. Clin Cancer Res. 2003;9:1121-1128.
    • (2003) Clin Cancer Res , vol.9 , pp. 1121-1128
    • Rassidakis, G.Z.1    Claret, F.X.2    Lai, R.3
  • 51
    • 0036848655 scopus 로고    scopus 로고
    • CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint
    • Doronkin S, Djagaeva I, Beckendorf SK. CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint. Development. 2002;129:5053-5064.
    • (2002) Development , vol.129 , pp. 5053-5064
    • Doronkin, S.1    Djagaeva, I.2    Beckendorf, S.K.3
  • 52
    • 0035478483 scopus 로고    scopus 로고
    • COP9 signalosome revisited: A novel mediator of protein degradation
    • Schwechheimer C, Deng XW. COP9 signalosome revisited: a novel mediator of protein degradation. Trends Cell Biol. 2001;11:420-426.
    • (2001) Trends Cell Biol , vol.11 , pp. 420-426
    • Schwechheimer, C.1    Deng, X.W.2
  • 53
    • 0036490442 scopus 로고    scopus 로고
    • Smart drugs: Tyrosine kinase inhibitors in cancer therapy
    • Shawver LK, Slamon D, Ullrich A. Smart drugs: tyrosine kinase inhibitors in cancer therapy. Cancer Cell. 2002;1:117-123.
    • (2002) Cancer Cell , vol.1 , pp. 117-123
    • Shawver, L.K.1    Slamon, D.2    Ullrich, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.