-
1
-
-
0842324788
-
Recycling the cell cycle: Cyclins revisited
-
Murray AW. Recycling the cell cycle: Cyclins revisited. Cell 2004; 116:221-34.
-
(2004)
Cell
, vol.116
, pp. 221-234
-
-
Murray, A.W.1
-
3
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
el-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B. WAF1, a potential mediator of p53 tumor suppression. Cell 1993; 75:817-25.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
el-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
4
-
-
0027731971
-
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
-
Gu Y, Turck CW, Morgan DO. Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature 1993; 366:707-10.
-
(1993)
Nature
, vol.366
, pp. 707-710
-
-
Gu, Y.1
Turck, C.W.2
Morgan, D.O.3
-
6
-
-
0028176483
-
Cloning of p27kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
-
Polyak K, Lee MH, Erdjument-Bromage H, Koff A, Roberts JM, Tempst P, Massague J. Cloning of p27kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 1994; 78:59-66.
-
(1994)
Cell
, vol.78
, pp. 59-66
-
-
Polyak, K.1
Lee, M.H.2
Erdjument-Bromage, H.3
Koff, A.4
Roberts, J.M.5
Tempst, P.6
Massague, J.7
-
7
-
-
0028363519
-
1 cyclin-cdk protein kinase activity, is related to p21
-
1 cyclin-cdk protein kinase activity, is related to p21. Cell 1994; 78:67-74.
-
(1994)
Cell
, vol.78
, pp. 67-74
-
-
Toyoshima, H.1
Hunter, T.2
-
8
-
-
0028988158
-
Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
-
Lee MH, Reynisdottir I, Massague J. Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes and Dev 1995; 9:639-49.
-
(1995)
Genes and Dev
, vol.9
, pp. 639-649
-
-
Lee, M.H.1
Reynisdottir, I.2
Massague, J.3
-
9
-
-
0028986932
-
p27kip1 chromosomal mapping to 12p 12-12p 13.1 and absence of mutations in human tumors
-
Ponce-Castaneda MV, Lee MH, Latres E, Polyak K, Lacombe L, Montgomery K, Mathew S, Krauter K, Sheinfeld J, Massague J, Cordon-Cardo C. p27kip1 chromosomal mapping to 12p 12-12p 13.1 and absence of mutations in human tumors. Cancer Res 1995; 55:1211-4.
-
(1995)
Cancer Res
, vol.55
, pp. 1211-1214
-
-
Ponce-Castaneda, M.V.1
Lee, M.H.2
Latres, E.3
Polyak, K.4
Lacombe, L.5
Montgomery, K.6
Mathew, S.7
Krauter, K.8
Sheinfeld, J.9
Massague, J.10
Cordon-Cardo, C.11
-
10
-
-
0028227197
-
A novel inhibitor of cyclin-Cdk activity detected in TGF-b-arrested epithelial cells
-
Slingerland J, Hengst L, Pan C, Alexander D, Stampfer M, Reed S. A novel inhibitor of cyclin-Cdk activity detected in TGF-b-arrested epithelial cells. Mol Cell Biol 1994; 14:3683-94.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3683-3694
-
-
Slingerland, J.1
Hengst, L.2
Pan, C.3
Alexander, D.4
Stampfer, M.5
Reed, S.6
-
11
-
-
0029665852
-
Crystal structures of the p27kip1 cyclin dependent-kinase inhibitor bound to the cyclin A-cdk 2 complex
-
Russo AA, Jeffrey PD, Patten AK, Massague J, Pavletich NP. Crystal structures of the p27kip1 cyclin dependent-kinase inhibitor bound to the cyclin A-cdk 2 complex. Nature 1996; 382:325-31.
-
(1996)
Nature
, vol.382
, pp. 325-331
-
-
Russo, A.A.1
Jeffrey, P.D.2
Patten, A.K.3
Massague, J.4
Pavletich, N.P.5
-
12
-
-
0027717617
-
p21 is a universal inhibitor of cyclin kinases
-
Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D. p21 is a universal inhibitor of cyclin kinases. Nature 1993; 366:701-4.
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
13
-
-
0034894258
-
Effects of macromolecular crowding on the intrinsically disordered proteins c-Fos and p27Kip1
-
Flaugh SL, Lumb KJ. Effects of macromolecular crowding on the intrinsically disordered proteins c-Fos and p27Kip1. Biomacromolecules 2001; 2:538-40.
-
(2001)
Biomacromolecules
, vol.2
, pp. 538-540
-
-
Flaugh, S.L.1
Lumb, K.J.2
-
14
-
-
0037154116
-
Functional consequences of preorganized helical structure in the intrinsically disordered cell-cycle inhibitor p27Kip1
-
Bienkiewicz EA, Adkins JN, Kevin J, Lumb KJ. Functional consequences of preorganized helical structure in the intrinsically disordered cell-cycle inhibitor p27Kip1. Biochemistry 2002; 41:752-9.
-
(2002)
Biochemistry
, vol.41
, pp. 752-759
-
-
Bienkiewicz, E.A.1
Adkins, J.N.2
Kevin, J.3
Lumb, K.J.4
-
15
-
-
0032749078
-
Intrinsically unstructured proteins: Reassessing the protein structure-function paradigm
-
Wright PE, Dyson HJ. Intrinsically unstructured proteins: Reassessing the protein structure-function paradigm. J Mol Biol 1999; 293:321-31.
-
(1999)
J Mol Biol
, vol.293
, pp. 321-331
-
-
Wright, P.E.1
Dyson, H.J.2
-
16
-
-
0035022941
-
Intrinsically disordered protein
-
Dunker AK, Lawson JD, Brown CJ, Williams RM, Romero P, Oh JS, Oldfield CJ, Campen AM, Ratliff CM, Hipps KW, Ausio J, Nissen MS, Reeves R, Kang C, Kissinger CR, Bailey RW, Griswold MD, Chiu W, Garner EC, Obradovic Z. Intrinsically disordered protein. J Mol Graph Model 2001; 19:26-59.
-
(2001)
J Mol Graph Model
, vol.19
, pp. 26-59
-
-
Dunker, A.K.1
Lawson, J.D.2
Brown, C.J.3
Williams, R.M.4
Romero, P.5
Oh, J.S.6
Oldfield, C.J.7
Campen, A.M.8
Ratliff, C.M.9
Hipps, K.W.10
Ausio, J.11
Nissen, M.S.12
Reeves, R.13
Kang, C.14
Kissinger, C.R.15
Bailey, R.W.16
Griswold, M.D.17
Chiu, W.18
Garner, E.C.19
Obradovic, Z.20
more..
-
17
-
-
0029904487
-
-
Weinreb PH, Zhen W, Poon AW, Conway KA, Lansbury PT. NACP, a protein implicated in Alzheimer's Disease and learning, is natively unfolded. Biochemistry 1996; 35:13709-15.
-
Weinreb PH, Zhen W, Poon AW, Conway KA, Lansbury PT. NACP, a protein implicated in Alzheimer's Disease and learning, is natively unfolded. Biochemistry 1996; 35:13709-15.
-
-
-
-
18
-
-
0034646289
-
-
Campbell KM, Terrell AR, Laybourn PJ, Lumb KJ. Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos. Biochemistry 2000; 39:2708-13.
-
Campbell KM, Terrell AR, Laybourn PJ, Lumb KJ. Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos. Biochemistry 2000; 39:2708-13.
-
-
-
-
19
-
-
1942466518
-
p27kip1 modulates cell migration through the regulation of RhoA activation
-
Besson A, Gurian-West M, Schmidt A, Hall A, Roberts JM. p27kip1 modulates cell migration through the regulation of RhoA activation. Genes and Dev 2004; 18:862-76.
-
(2004)
Genes and Dev
, vol.18
, pp. 862-876
-
-
Besson, A.1
Gurian-West, M.2
Schmidt, A.3
Hall, A.4
Roberts, J.M.5
-
20
-
-
0037216528
-
Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions
-
McAllister SS, Becker-Hapak M, Pintucci G, Pagano M, Dowdy SF. Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions. Mol Cell Biol 2003; 23:216-28.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 216-228
-
-
McAllister, S.S.1
Becker-Hapak, M.2
Pintucci, G.3
Pagano, M.4
Dowdy, S.F.5
-
21
-
-
12344274508
-
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
-
Baldassarre G, Belletti B, Nicoloso MS, Schiappacassi M, Vecchione A, Spessotto P, Morrione A, Canzonieri V, Colombatti A. p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion. Cancer Cell 2005; 7:51-63.
-
(2005)
Cancer Cell
, vol.7
, pp. 51-63
-
-
Baldassarre, G.1
Belletti, B.2
Nicoloso, M.S.3
Schiappacassi, M.4
Vecchione, A.5
Spessotto, P.6
Morrione, A.7
Canzonieri, V.8
Colombatti, A.9
-
22
-
-
0035853813
-
Direct binding of the signal-transducing adaptor Grb2 facilitates down-regulation of the Cyclin-dependent Kinase Inhibitor p27Kip1
-
Sugiyama Y, Tomoda K, Tanaka T, Arata Y, Yoneda-Kato N, Kato JY. Direct binding of the signal-transducing adaptor Grb2 facilitates down-regulation of the Cyclin-dependent Kinase Inhibitor p27Kip1. J Biol Chem 2001; 276:12084-90.
-
(2001)
J Biol Chem
, vol.276
, pp. 12084-12090
-
-
Sugiyama, Y.1
Tomoda, K.2
Tanaka, T.3
Arata, Y.4
Yoneda-Kato, N.5
Kato, J.Y.6
-
23
-
-
0037570624
-
p27Kip1 Inhibition of GRB2-SOS formation can regulate Ras activation
-
Moeller SJ, Head ED, Sheaff RJ. p27Kip1 Inhibition of GRB2-SOS formation can regulate Ras activation. Mol Cell Biol 2003; 23:3735-52.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 3735-3752
-
-
Moeller, S.J.1
Head, E.D.2
Sheaff, R.J.3
-
24
-
-
0027170920
-
SH3 domains direct cellular localization of signaling molecules
-
Bar-Sagi D, Rotin D, Batzer A, Mandiyan V, Schlessinger J. SH3 domains direct cellular localization of signaling molecules. Cell 1993; 74:83-91.
-
(1993)
Cell
, vol.74
, pp. 83-91
-
-
Bar-Sagi, D.1
Rotin, D.2
Batzer, A.3
Mandiyan, V.4
Schlessinger, J.5
-
25
-
-
0037047268
-
Akt-dependent phosphorylation of p27 promotes binding to 14-3-3 and cytoplasmic localization
-
Fujita N, Sato S, Katayama K, Tsuruo T. Akt-dependent phosphorylation of p27 promotes binding to 14-3-3 and cytoplasmic localization. J Biol Chem 2002; 277:28706-13.
-
(2002)
J Biol Chem
, vol.277
, pp. 28706-28713
-
-
Fujita, N.1
Sato, S.2
Katayama, K.3
Tsuruo, T.4
-
26
-
-
1542677089
-
Phosphorylation of p27 at threonine 198 by p90 ribosomal protein S6 kinase promotes its binding to 14-3-3 and cytoplasmic localization
-
Fujita N, Sato S, Tsuruo T. Phosphorylation of p27 at threonine 198 by p90 ribosomal protein S6 kinase promotes its binding to 14-3-3 and cytoplasmic localization. J Biol Chem 2003; 278:49254-60.
-
(2003)
J Biol Chem
, vol.278
, pp. 49254-49260
-
-
Fujita, N.1
Sato, S.2
Tsuruo, T.3
-
27
-
-
3142512358
-
14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27
-
Sekimoto T, Fukumoto M, Yoneda Y. 14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27. EMBO J 2004; 23:1934-42.
-
(2004)
EMBO J
, vol.23
, pp. 1934-1942
-
-
Sekimoto, T.1
Fukumoto, M.2
Yoneda, Y.3
-
28
-
-
0033913977
-
Minimal requirements for the nuclear localization of p27(Kip1), a cyclin-dependent kinase inhibitor
-
Zeng Y, Hirano K, Hirano M, Nishimura J, Kanaide H. Minimal requirements for the nuclear localization of p27(Kip1), a cyclin-dependent kinase inhibitor. Biochem Biophys Res Commun 2000; 274:37-42.
-
(2000)
Biochem Biophys Res Commun
, vol.274
, pp. 37-42
-
-
Zeng, Y.1
Hirano, K.2
Hirano, M.3
Nishimura, J.4
Kanaide, H.5
-
29
-
-
0037242575
-
CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis
-
Connor MK, Kotchetkov R, Cariou S, Resch A, Lupetti R, Beniston RG, Melchior F, Hengst L, Slingerland JM. CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis. Mol Biol Cell 2003; 14:201-13.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 201-213
-
-
Connor, M.K.1
Kotchetkov, R.2
Cariou, S.3
Resch, A.4
Lupetti, R.5
Beniston, R.G.6
Melchior, F.7
Hengst, L.8
Slingerland, J.M.9
-
30
-
-
0042812981
-
Cyclin E-mediate delimination
-
Muller D, Thieke K, Burgin A, Dickmanns A, Eilers M. Cyclin E-mediate delimination. EMBO J 2000; 19:2168-80.
-
(2000)
EMBO J
, vol.19
, pp. 2168-2180
-
-
Muller, D.1
Thieke, K.2
Burgin, A.3
Dickmanns, A.4
Eilers, M.5
-
31
-
-
21844431711
-
The regulation of S phase initiation by p27Kip1 in NIH3T3 cells
-
Sa G, Guo Y, Stacey DW. The regulation of S phase initiation by p27Kip1 in NIH3T3 cells. Cell Cycle 2005; 4:618-27.
-
(2005)
Cell Cycle
, vol.4
, pp. 618-627
-
-
Sa, G.1
Guo, Y.2
Stacey, D.W.3
-
32
-
-
33749591900
-
p27Kip1 and cyclin dependent kinase 2 regulate passage through the restriction point
-
Hitomi M, Yang K, Ya, Guo Y, Fretthold J, Harwalkar J, Stacey D. p27Kip1 and cyclin dependent kinase 2 regulate passage through the restriction point. Cell Cycle 2006; 5:2281-9.
-
(2006)
Cell Cycle
, vol.5
, pp. 2281-2289
-
-
Hitomi, M.1
Yang, K.2
Ya3
Guo, Y.4
Fretthold, J.5
Harwalkar, J.6
Stacey, D.7
-
33
-
-
25444526687
-
Using kinetic studies to uncover new Rb functions in inhibiting cell cycle progression
-
Ji P, Zhu L. Using kinetic studies to uncover new Rb functions in inhibiting cell cycle progression. Cell Cycle 2005; 4:373-5.
-
(2005)
Cell Cycle
, vol.4
, pp. 373-375
-
-
Ji, P.1
Zhu, L.2
-
34
-
-
15844384256
-
A syndrome of multiorgan hyperplasia with features of gigantism,tumorigenesis, and female sterility in p27(Kip1)-deficient mice
-
Fero ML, Rivkin M, Tasch M, Porter P, Carow CE, Firpo E, Polyak K, Tsai LH, Broudy V, Perlmutter RM, Kaushansky K, Roberts JM. A syndrome of multiorgan hyperplasia with features of gigantism,tumorigenesis, and female sterility in p27(Kip1)-deficient mice. Cell 1996; 85:733-44.
-
(1996)
Cell
, vol.85
, pp. 733-744
-
-
Fero, M.L.1
Rivkin, M.2
Tasch, M.3
Porter, P.4
Carow, C.E.5
Firpo, E.6
Polyak, K.7
Tsai, L.H.8
Broudy, V.9
Perlmutter, R.M.10
Kaushansky, K.11
Roberts, J.M.12
-
35
-
-
15844415946
-
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1)
-
Kiyokawa H, Kineman RD, Manova-Todorova KO, Soares VC, Hoffman ES, Ono M, Khanam D, Hayday AC, Frohman LA, Koff A. Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell 1996; 85:721-32.
-
(1996)
Cell
, vol.85
, pp. 721-732
-
-
Kiyokawa, H.1
Kineman, R.D.2
Manova-Todorova, K.O.3
Soares, V.C.4
Hoffman, E.S.5
Ono, M.6
Khanam, D.7
Hayday, A.C.8
Frohman, L.A.9
Koff, A.10
-
36
-
-
0030010591
-
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
-
Nakayama K, Ishida N, Shirane M, Inomata A, Inoue T, Shishido N, Horii I, Loh DY, Nakayama K. Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 1996; 85:707-20.
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
Inomata, A.4
Inoue, T.5
Shishido, N.6
Horii, I.7
Loh, D.Y.8
Nakayama, K.9
-
39
-
-
0029007867
-
Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies
-
Kawamata N, Morosetti R, Miller C, Park D, Spirin K, Nakamaki T, Takeuchi S, Hatta Y, Simpson J, Wilcyznski S, Lee YY, Bartram CR, Koeffler HP. Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies. Cancer Res 1995; 55:2266-9.
-
(1995)
Cancer Res
, vol.55
, pp. 2266-2269
-
-
Kawamata, N.1
Morosetti, R.2
Miller, C.3
Park, D.4
Spirin, K.5
Nakamaki, T.6
Takeuchi, S.7
Hatta, Y.8
Simpson, J.9
Wilcyznski, S.10
Lee, Y.Y.11
Bartram, C.R.12
Koeffler, H.P.13
-
40
-
-
0034092911
-
Regulation of the cdk inhibitor p27 and its deregulation in cancer
-
Slingerland J, Pagano M. Regulation of the cdk inhibitor p27 and its deregulation in cancer. J Cell Physiol 2000; 183:10-7.
-
(2000)
J Cell Physiol
, vol.183
, pp. 10-17
-
-
Slingerland, J.1
Pagano, M.2
-
41
-
-
0028986932
-
p27Kip1: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors
-
Ponce-Castaneda MV, Lee M, Latres E, Polyak K, Lacombe L, Montgomery K, Mathew S, Krauter K, Sheinfeld J, Massague J, Cordon-Cardo C. p27Kip1: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. Cancer Res 1995; 55:1211-4.
-
(1995)
Cancer Res
, vol.55
, pp. 1211-1214
-
-
Ponce-Castaneda, M.V.1
Lee, M.2
Latres, E.3
Polyak, K.4
Lacombe, L.5
Montgomery, K.6
Mathew, S.7
Krauter, K.8
Sheinfeld, J.9
Massague, J.10
Cordon-Cardo, C.11
-
42
-
-
0035835828
-
p27(Kip1): Regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer
-
Philipp-Staheli J, Payne S, Kemp C. p27(Kip1): Regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer. Exp Cell Res 2001; 264:148-68.
-
(2001)
Exp Cell Res
, vol.264
, pp. 148-168
-
-
Philipp-Staheli, J.1
Payne, S.2
Kemp, C.3
-
43
-
-
0032511848
-
The murine gene p27Kip1 is haplo-insufficient for tumour suppression
-
Fero M, Randel E, Gurley K, Roberts J, Kemp C. The murine gene p27Kip1 is haplo-insufficient for tumour suppression. Nature 1998; 396:177-80.
-
(1998)
Nature
, vol.396
, pp. 177-180
-
-
Fero, M.1
Randel, E.2
Gurley, K.3
Roberts, J.4
Kemp, C.5
-
44
-
-
25444504308
-
An unusual gene dosage effect of p27Kip1 in a mouse model of prostate cancer
-
Abate-Shen C, Shen MM. An unusual gene dosage effect of p27Kip1 in a mouse model of prostate cancer. Cell Cycle 2005; 4:426-8.
-
(2005)
Cell Cycle
, vol.4
, pp. 426-428
-
-
Abate-Shen, C.1
Shen, M.M.2
-
45
-
-
0031439355
-
Promoting apoptosis: A novel activity associated with the cyclin-dependent kinase inhibitor p27
-
Katayose Y, Kim M, Rakkar AN, Li Z, Cowan KH, Seth P. Promoting apoptosis: A novel activity associated with the cyclin-dependent kinase inhibitor p27. Cancer Res 1997; 57:5441-5.
-
(1997)
Cancer Res
, vol.57
, pp. 5441-5445
-
-
Katayose, Y.1
Kim, M.2
Rakkar, A.N.3
Li, Z.4
Cowan, K.H.5
Seth, P.6
-
46
-
-
0032429122
-
Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts
-
An B, Goldfarb RH, Siman R, Dou QP. Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts. Cell Death Differ 1998; 12:1062-75.
-
(1998)
Cell Death Differ
, vol.12
, pp. 1062-1075
-
-
An, B.1
Goldfarb, R.H.2
Siman, R.3
Dou, Q.P.4
-
47
-
-
2342598475
-
The role of p27Kip1 in proteasome inhibitor induced apoptosis
-
Drexler HCA. The role of p27Kip1 in proteasome inhibitor induced apoptosis. Cell Cycle 2003; 2:438-41.
-
(2003)
Cell Cycle
, vol.2
, pp. 438-441
-
-
Drexler, H.C.A.1
-
48
-
-
0032012062
-
Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: Role of a caspase cascade
-
Levkau B, Koyama H, Raines EW, Clurman BE, Herren B, Orth K, Roberts JM, Ross R. Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: Role of a caspase cascade. Mol Cell 1998; 4:553-63.
-
(1998)
Mol Cell
, vol.4
, pp. 553-563
-
-
Levkau, B.1
Koyama, H.2
Raines, E.W.3
Clurman, B.E.4
Herren, B.5
Orth, K.6
Roberts, J.M.7
Ross, R.8
-
49
-
-
0033580135
-
p27Kip1 induces drug resistance by preventing apoptosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells
-
Eymin B, Haugg M, Droin N, Sordet O, Dimanche-Boitrel MT, Solary E. p27Kip1 induces drug resistance by preventing apoptosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells. Oncogene 1999; 18:1411-8.
-
(1999)
Oncogene
, vol.18
, pp. 1411-1418
-
-
Eymin, B.1
Haugg, M.2
Droin, N.3
Sordet, O.4
Dimanche-Boitrel, M.T.5
Solary, E.6
-
50
-
-
0031759170
-
Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration
-
Nagahara H, Vocero-Akbani AM, Snyder EL, Ho A, Latham DG, Lissy NA, Becker-Hapak M, Ezhevsky SA, Dowdy SF. Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration. Nat Med 1998; 4:1449-52.
-
(1998)
Nat Med
, vol.4
, pp. 1449-1452
-
-
Nagahara, H.1
Vocero-Akbani, A.M.2
Snyder, E.L.3
Ho, A.4
Latham, D.G.5
Lissy, N.A.6
Becker-Hapak, M.7
Ezhevsky, S.A.8
Dowdy, S.F.9
-
51
-
-
0034842489
-
Overexpression of p27(Kip1) by doxycycline-regulated adenoviral vectors inhibits endothelial cell proliferation and migration and impairs angiogenesis
-
Goukassian D, Diez-Juan A, Asahara T, Schratzberger P, Silver M, Murayama T, Isner JM, Andres V. Overexpression of p27(Kip1) by doxycycline-regulated adenoviral vectors inhibits endothelial cell proliferation and migration and impairs angiogenesis. FASEB J 2001; 11:1877-85.
-
(2001)
FASEB J
, vol.11
, pp. 1877-1885
-
-
Goukassian, D.1
Diez-Juan, A.2
Asahara, T.3
Schratzberger, P.4
Silver, M.5
Murayama, T.6
Isner, J.M.7
Andres, V.8
-
52
-
-
0035912863
-
Role for p27(Kip1) in vascular smooth muscle cell migration
-
Sun J, Marx SO, Chen HJ, Poon M, Marks AR, Rabbani LE. Role for p27(Kip1) in vascular smooth muscle cell migration. Circulation 2001; 103:2967-72.
-
(2001)
Circulation
, vol.103
, pp. 2967-2972
-
-
Sun, J.1
Marx, S.O.2
Chen, H.J.3
Poon, M.4
Marks, A.R.5
Rabbani, L.E.6
-
53
-
-
0037423864
-
Coordinate control of proliferation and migration by the p27 Kip1/cyclin-dependent kinase/Retinoblastoma pathway in vascular smooth muscle cells and fibroblasts
-
Diez-Juan A, Andres V. Coordinate control of proliferation and migration by the p27 Kip1/cyclin-dependent kinase/Retinoblastoma pathway in vascular smooth muscle cells and fibroblasts. Circ Res 2003; 92:402-10.
-
(2003)
Circ Res
, vol.92
, pp. 402-410
-
-
Diez-Juan, A.1
Andres, V.2
-
54
-
-
0642375769
-
Effect of p27 Kip1 on the ability of invasion and metastasis of an oral cancer cell line
-
Supriatno, Harada K, Kawaguchi S, Yoshida H, Sato M. Effect of p27 Kip1 on the ability of invasion and metastasis of an oral cancer cell line. Oncol Rep 2003; 10:527-32.
-
(2003)
Oncol Rep
, vol.10
, pp. 527-532
-
-
Supriatno1
Harada, K.2
Kawaguchi, S.3
Yoshida, H.4
Sato, M.5
-
55
-
-
33751255370
-
Coupling cell cycle exit, neuronal differentiation and migration in cortical neurogenesis
-
Nguyen L, Besson A, Roberts JM, Guillemot F. Coupling cell cycle exit, neuronal differentiation and migration in cortical neurogenesis. Cell Cycle 2006; 5:2314-8.
-
(2006)
Cell Cycle
, vol.5
, pp. 2314-2318
-
-
Nguyen, L.1
Besson, A.2
Roberts, J.M.3
Guillemot, F.4
-
56
-
-
0033594123
-
Rho GTPases control polarity, protrusion,and adhesion during cell movement
-
Nobes C, Hall A. Rho GTPases control polarity, protrusion,and adhesion during cell movement. J Cell Biol 1999; 144:1235-44.
-
(1999)
J Cell Biol
, vol.144
, pp. 1235-1244
-
-
Nobes, C.1
Hall, A.2
-
57
-
-
0035833247
-
RhoA is required for monocyte tail retraction durino transendothelial migration
-
Worthylake R, Lemoine S, Watson J, Burridge K. RhoA is required for monocyte tail retraction durino transendothelial migration. J Cell Biol 2001; 154:147-60.
-
(2001)
J Cell Biol
, vol.154
, pp. 147-160
-
-
Worthylake, R.1
Lemoine, S.2
Watson, J.3
Burridge, K.4
-
58
-
-
34248210871
-
Focal adhesion kinase sup- presses Rho activity to promote focal adhesion turnover
-
Ren XD, Kiosses WB, Sieg DJ, Otey CA, Schlaepfer DD, Schwartz MA. Focal adhesion kinase sup- presses Rho activity to promote focal adhesion turnover. J Cell Sci 20001; 13:3637-78.
-
(2001)
J Cell Sci
, vol.13
, pp. 3637-3678
-
-
Ren, X.D.1
Kiosses, W.B.2
Sieg, D.J.3
Otey, C.A.4
Schlaepfer, D.D.5
Schwartz, M.A.6
-
59
-
-
0035158377
-
RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity
-
Arthur WT, Burridge K. RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity. Mol Biol Cell 2001; 12:2711-20.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 2711-2720
-
-
Arthur, W.T.1
Burridge, K.2
-
60
-
-
0035152391
-
Integrin-mediated adhesion regulates cell polarity and membrane protrusion through the Rho family of GTPases
-
Cox EA, Sastry SK, Huttenlocher A. Integrin-mediated adhesion regulates cell polarity and membrane protrusion through the Rho family of GTPases. Mol Biol Cell 2001; 12:265-77.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 265-277
-
-
Cox, E.A.1
Sastry, S.K.2
Huttenlocher, A.3
-
61
-
-
0035865137
-
Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility
-
Sahai E, Olson MF, Marshall CJ. Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility. EMBO J 2001; 20:755-66.
-
(2001)
EMBO J
, vol.20
, pp. 755-766
-
-
Sahai, E.1
Olson, M.F.2
Marshall, C.J.3
-
62
-
-
0042349229
-
ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility
-
Vial E, Sahai E, Marshall CJ. ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility. Cancer Cell 2003; 4:67-79.
-
(2003)
Cancer Cell
, vol.4
, pp. 67-79
-
-
Vial, E.1
Sahai, E.2
Marshall, C.J.3
-
63
-
-
0026778133
-
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
-
Ridley AJ, Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 1992; 70:389-99.
-
(1992)
Cell
, vol.70
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
64
-
-
9444242736
-
Regulation of myosin phosphatase by Rho and Rho- associated kinase (Rho-kinase)
-
Kimura K, Ito M, Amano M, Chihara K, Fukata Y, Nakafuku M, Yamamori B, Feng J, Nakano T, Okawa K, Iwamatsu A, Kaibuchi K. Regulation of myosin phosphatase by Rho and Rho- associated kinase (Rho-kinase). Science 1996; 273:245-8.
-
(1996)
Science
, vol.273
, pp. 245-248
-
-
Kimura, K.1
Ito, M.2
Amano, M.3
Chihara, K.4
Fukata, Y.5
Nakafuku, M.6
Yamamori, B.7
Feng, J.8
Nakano, T.9
Okawa, K.10
Iwamatsu, A.11
Kaibuchi, K.12
-
65
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville S, Hall A. Rho GTPases in cell biology. Nature 2002; 420:629-35.
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
66
-
-
0036222784
-
Adhesion assembly,disassembly and turnover in migrating cells - Over and over and over again
-
Webb DJ, Parsons JT, Horwitz AF. Adhesion assembly,disassembly and turnover in migrating cells - Over and over and over again. Nat Cell Biol 2002; 4:E97-100.
-
(2002)
Nat Cell Biol
, vol.4
-
-
Webb, D.J.1
Parsons, J.T.2
Horwitz, A.F.3
-
67
-
-
0037157872
-
Cytoplasmic p21 Cip1/Waf1 regulates neurite remodeling by inhibiting Rho-kinase activity
-
Tanaka H, Yamashita T, Asada M, Mizutani S, Yoshikawa H, Tohyama M. Cytoplasmic p21 Cip1/Waf1 regulates neurite remodeling by inhibiting Rho-kinase activity. J Cell Biol 2002; 158:321-9.
-
(2002)
J Cell Biol
, vol.158
, pp. 321-329
-
-
Tanaka, H.1
Yamashita, T.2
Asada, M.3
Mizutani, S.4
Yoshikawa, H.5
Tohyama, M.6
-
68
-
-
0347717882
-
Cytoplasmic p21 is involved in Ras-induced inhibition of the ROCK/LIMK/Cofilin pathway
-
Lee S, Helfman DM. Cytoplasmic p21 is involved in Ras-induced inhibition of the ROCK/LIMK/Cofilin pathway. J Biol Chem 2003; 279:1885-91.
-
(2003)
J Biol Chem
, vol.279
, pp. 1885-1891
-
-
Lee, S.1
Helfman, D.M.2
-
69
-
-
0346101745
-
p57 Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleus
-
Yokoo T, Toyoshima H, Miura M, Wang Y, Iida KT, Suzuki H, Sone H, Shimano H, Gotoda T, Nishimori S, Tanaka K, Yamada N. p57 Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleus. J Biol Chem 2003; 278:52919-23.
-
(2003)
J Biol Chem
, vol.278
, pp. 52919-52923
-
-
Yokoo, T.1
Toyoshima, H.2
Miura, M.3
Wang, Y.4
Iida, K.T.5
Suzuki, H.6
Sone, H.7
Shimano, H.8
Gotoda, T.9
Nishimori, S.10
Tanaka, K.11
Yamada, N.12
-
71
-
-
0032537819
-
Signals from Ras and Rho GTPases interact to regulate expression of p21 Waf1/Cip1
-
Olson MF, Paterson HF, Marshall CJ. Signals from Ras and Rho GTPases interact to regulate expression of p21 Waf1/Cip1. Nature 1998; 394:295-9.
-
(1998)
Nature
, vol.394
, pp. 295-299
-
-
Olson, M.F.1
Paterson, H.F.2
Marshall, C.J.3
-
72
-
-
0033525188
-
RhoA stimulates p27 Kip1 degradation through its regulation of cyclin E/CDK2 activity
-
Hu W, Bellone C, Baldassare J. RhoA stimulates p27 Kip1 degradation through its regulation of cyclin E/CDK2 activity. J Biol Chem 1999; 274:3396-401.
-
(1999)
J Biol Chem
, vol.274
, pp. 3396-3401
-
-
Hu, W.1
Bellone, C.2
Baldassare, J.3
-
73
-
-
0037053407
-
Rho activity can alter the translation of mRNA and is important for Ras V12 -induced transformation in a manner dependent on p27 status
-
Vidal A, Millard S, Miller J, Koff A. Rho activity can alter the translation of mRNA and is important for Ras V12 -induced transformation in a manner dependent on p27 status. J Biol Chem 2002; 277:16433-40.
-
(2002)
J Biol Chem
, vol.277
, pp. 16433-16440
-
-
Vidal, A.1
Millard, S.2
Miller, J.3
Koff, A.4
-
74
-
-
0347717882
-
Cytoplasmic p21Cip1 is involved in Ras-induced inhibition of the ROCK/LIMK/cofilin pathway
-
Lee S, Helfman DM. Cytoplasmic p21Cip1 is involved in Ras-induced inhibition of the ROCK/LIMK/cofilin pathway. J Biol Chem 2004; 279:1885-91.
-
(2004)
J Biol Chem
, vol.279
, pp. 1885-1891
-
-
Lee, S.1
Helfman, D.M.2
-
75
-
-
0034643331
-
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
-
Medema RH, Kops GJ, Bos JL, Burgering BM. AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1. Nature 2000; 404:782-7.
-
(2000)
Nature
, vol.404
, pp. 782-787
-
-
Medema, R.H.1
Kops, G.J.2
Bos, J.L.3
Burgering, B.M.4
-
76
-
-
0034459180
-
Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27kip1
-
Dijkers PF, Medema RH, Pals, Banerji CL, Thomas NSB, Lam EWF, Burgering BMT, Raaijmakers JAM, Lammers JWJ, Koenderman L, Coffer PJ. Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27kip1. Mol Cell Biol 2000; 20:9138-48.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 9138-9148
-
-
Dijkers, P.F.1
Medema, R.H.2
Pals3
Banerji, C.L.4
Thomas, N.S.B.5
Lam, E.W.F.6
Burgering, B.M.T.7
Raaijmakers, J.A.M.8
Lammers, J.W.J.9
Koenderman, L.10
Coffer, P.J.11
-
77
-
-
0034637524
-
Increased AKT activity contributes to prostate cancer Progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression
-
Graff JR, Konicek BW, McNulty AM, Wangi Z, Houck K, Allen S, Paul JD, Hbaiu A, Goode RG, George E, Sandusky GE, Robert L, Vessellai RL, Neubauer BL. Increased AKT activity contributes to prostate cancer Progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression. J Biol Chem 2000; 275:24500-5.
-
(2000)
J Biol Chem
, vol.275
, pp. 24500-24505
-
-
Graff, J.R.1
Konicek, B.W.2
McNulty, A.M.3
Wangi, Z.4
Houck, K.5
Allen, S.6
Paul, J.D.7
Hbaiu, A.8
Goode, R.G.9
George, E.10
Sandusky, G.E.11
Robert, L.12
Vessellai, R.L.13
Neubauer, B.L.14
-
78
-
-
0034698170
-
Inhibition of the Phosphoinositide 3-Kinase pathway induces a senescence-like arrest mediated by p27Kip1
-
Collado M, Medema RH, García-Cao I, Dubuisson MLN, Barradas M, Glassford J, Rivas C, Burgering BMT, Serrano M, Lama EWF. Inhibition of the Phosphoinositide 3-Kinase pathway induces a senescence-like arrest mediated by p27Kip1. J Biol Chem 2000; 275:21960-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 21960-21968
-
-
Collado, M.1
Medema, R.H.2
García-Cao, I.3
Dubuisson, M.L.N.4
Barradas, M.5
Glassford, J.6
Rivas, C.7
Burgering, B.M.T.8
Serrano, M.9
Lama, E.W.F.10
-
79
-
-
0037094096
-
The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2
-
Stahl M, Dijkers PF, Kops GJ, Lens SM, Coffer PJ, Burgering BM, Medema RH. The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2. J Immunol 2002; 168:5024-31.
-
(2002)
J Immunol
, vol.168
, pp. 5024-5031
-
-
Stahl, M.1
Dijkers, P.F.2
Kops, G.J.3
Lens, S.M.4
Coffer, P.J.5
Burgering, B.M.6
Medema, R.H.7
-
80
-
-
0037113939
-
Increased hepatic forkhead box M1B (FoxM1B) levels in old-aged mice stimulated liver regeneration through diminished p27Kip1 protein levels and increased Cdc25B expression
-
Wang X, Krupczak-Hollis K, Tan Y, Dennewitz MB, Adami GR, Costa RH. Increased hepatic forkhead box M1B (FoxM1B) levels in old-aged mice stimulated liver regeneration through diminished p27Kip1 protein levels and increased Cdc25B expression. J Biol Chem 2002; 277:44310-6.
-
(2002)
J Biol Chem
, vol.277
, pp. 44310-44316
-
-
Wang, X.1
Krupczak-Hollis, K.2
Tan, Y.3
Dennewitz, M.B.4
Adami, G.R.5
Costa, R.H.6
-
81
-
-
0037017396
-
-
Dijkers PF, Birkenkamp KU, Lam EWF, N Thomas SB, Lammers JWJ, Koenderman L, Coffer PJ. FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: Protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity. J Cell Biol 2002; 156:531-42.
-
Dijkers PF, Birkenkamp KU, Lam EWF, N Thomas SB, Lammers JWJ, Koenderman L, Coffer PJ. FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: Protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity. J Cell Biol 2002; 156:531-42.
-
-
-
-
82
-
-
16844362291
-
Activation of p27Kip1. Expression by E2F1: A negative feedback mechanism
-
Wang C, Hou X, Mohapatra S, Ma Y, Cress WD, Pledger WJ, Chen J. Activation of p27Kip1. Expression by E2F1: A negative feedback mechanism. J Biol Chem 2005; 280:12339-43.
-
(2005)
J Biol Chem
, vol.280
, pp. 12339-12343
-
-
Wang, C.1
Hou, X.2
Mohapatra, S.3
Ma, Y.4
Cress, W.D.5
Pledger, W.J.6
Chen, J.7
-
83
-
-
2142662252
-
Reciprocal control of forkhead box O3a and c-myc via the phosphatidylinositol 3-kinase pathway coordinately regulates p27Kip1 levels
-
Chandramohan V, Jeay S, Pianetti S, Sonenshein SGE. Reciprocal control of forkhead box O3a and c-myc via the phosphatidylinositol 3-kinase pathway coordinately regulates p27Kip1 levels. J Immunol 2004; 172:5522-7.
-
(2004)
J Immunol
, vol.172
, pp. 5522-5527
-
-
Chandramohan, V.1
Jeay, S.2
Pianetti, S.3
Sonenshein, S.G.E.4
-
84
-
-
0035967099
-
Repression of transcription of the p27Kip1 cyclin-dependent kinase inhibitor gene by c-Myc
-
Yang W, Shen J, Wu M, Arsura M, FitzGerald M, Suldan Z, Dong W, Kim DW, Hofmann CS, Pianetti S, Romieu-Mourez R, Freedman LP, Sonenshein GE. Repression of transcription of the p27Kip1 cyclin-dependent kinase inhibitor gene by c-Myc. Oncogene 2001; 20:1688-02.
-
(2001)
Oncogene
, vol.20
, pp. 1688-1602
-
-
Yang, W.1
Shen, J.2
Wu, M.3
Arsura, M.4
FitzGerald, M.5
Suldan, Z.6
Dong, W.7
Kim, D.W.8
Hofmann, C.S.9
Pianetti, S.10
Romieu-Mourez, R.11
Freedman, L.P.12
Sonenshein, G.E.13
-
85
-
-
0035093090
-
Role of Sp1 in the induction of p27 gene expression in vascular smooth muscle cells in vitro and after balloon angioplasty
-
Andrés V, Ureña J, Poch E, Chen D, Goukassian D. Role of Sp1 in the induction of p27 gene expression in vascular smooth muscle cells in vitro and after balloon angioplasty. Arteriosclerosis Thrombosis and Vascular Biology 2001; 21:342-7.
-
(2001)
Arteriosclerosis Thrombosis and Vascular Biology
, vol.21
, pp. 342-347
-
-
Andrés, V.1
Ureña, J.2
Poch, E.3
Chen, D.4
Goukassian, D.5
-
86
-
-
26844548626
-
Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c
-
Karnik SK, Hughes CM, Gu X, Rozenblatt-Rosen O, McLean GW, Yue Xiong Y, Meyerson M, Kim SK. Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c. Proc Natl Acad Sci USA 2005; 102:14659-64.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14659-14664
-
-
Karnik, S.K.1
Hughes, C.M.2
Gu, X.3
Rozenblatt-Rosen, O.4
McLean, G.W.5
Yue Xiong, Y.6
Meyerson, M.7
Kim, S.K.8
-
88
-
-
0036799377
-
PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization
-
Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL. PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. Nat Med 2002; 8:1145-52.
-
(2002)
Nat Med
, vol.8
, pp. 1145-1152
-
-
Shin, I.1
Yakes, F.M.2
Rojo, F.3
Shin, N.Y.4
Bakin, A.V.5
Baselga, J.6
Arteaga, C.L.7
-
89
-
-
18644370396
-
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer
-
Viglietto G, Motti ML, Bruni P, Melillo RM, D'Alessio A, Califano D, Vinci F, Chiappetta G, Tsichlis P, Bellacosa A, Fusco A, Santoro M. Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer. Nat Med 2002; 8:1136-44.
-
(2002)
Nat Med
, vol.8
, pp. 1136-1144
-
-
Viglietto, G.1
Motti, M.L.2
Bruni, P.3
Melillo, R.M.4
D'Alessio, A.5
Califano, D.6
Vinci, F.7
Chiappetta, G.8
Tsichlis, P.9
Bellacosa, A.10
Fusco, A.11
Santoro, M.12
-
90
-
-
0037047268
-
Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization
-
Fujita N, Sato S, Katayama K, Tsuruo T. Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization. J Biol Chem 2002; 277:28706-13.
-
(2002)
J Biol Chem
, vol.277
, pp. 28706-28713
-
-
Fujita, N.1
Sato, S.2
Katayama, K.3
Tsuruo, T.4
-
91
-
-
1542677089
-
Phosphorylation of p27Kip1 at threonine 198 by p90 localization
-
Fujita N, Sato S, Tsuruo T. Phosphorylation of p27Kip1 at threonine 198 by p90 localization. J Biol Chem 2003; 278:49254-60.
-
(2003)
J Biol Chem
, vol.278
, pp. 49254-49260
-
-
Fujita, N.1
Sato, S.2
Tsuruo, T.3
-
92
-
-
0042197268
-
Focus on p27. Are p27 and p21 cytoplasmic oncoproteins?
-
Blagosklonny MV. Focus on p27. Are p27 and p21 cytoplasmic oncoproteins? Cell Cycle 2002; 1:391-3.
-
(2002)
Cell Cycle
, vol.1
, pp. 391-393
-
-
Blagosklonny, M.V.1
-
93
-
-
0041696635
-
Focus on p27: Keeping p27 Kip1 in the cytoplasm: A second front in cancer's war on p27
-
Reed SI. Focus on p27: Keeping p27 Kip1 in the cytoplasm: A second front in cancer's war on p27. Cell Cycle 2002; 1:389-90.
-
(2002)
Cell Cycle
, vol.1
, pp. 389-390
-
-
Reed, S.I.1
-
94
-
-
3142512358
-
14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)
-
Sekimoto T, Fukumoto M, Yoneda Y. 14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1). EMBO J 2004; 23:1934-42.
-
(2004)
EMBO J
, vol.23
, pp. 1934-1942
-
-
Sekimoto, T.1
Fukumoto, M.2
Yoneda, Y.3
-
95
-
-
31544471421
-
Tyrosine phosphorylation modulates binding preference to cyclin-dependent kinases and subcellular localization of p27 Kip1 in the acute promyelocytic leukemia cell line NB4
-
Kardinal C, Dangers M, Kardinal A, Koch A, Brandt DT, Tamura T, Welte K. Tyrosine phosphorylation modulates binding preference to cyclin-dependent kinases and subcellular localization of p27 Kip1 in the acute promyelocytic leukemia cell line NB4. Blood 2006; 107:1133-40.
-
(2006)
Blood
, vol.107
, pp. 1133-1140
-
-
Kardinal, C.1
Dangers, M.2
Kardinal, A.3
Koch, A.4
Brandt, D.T.5
Tamura, T.6
Welte, K.7
-
96
-
-
0037177386
-
Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export
-
Ishida N, Hara T, Kamura T, Yoshida M, Nakayama K, Nakayama KI. Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export. J Biol Chem 2002; 277:14355-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 14355-14358
-
-
Ishida, N.1
Hara, T.2
Kamura, T.3
Yoshida, M.4
Nakayama, K.5
Nakayama, K.I.6
-
97
-
-
0033545636
-
Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
-
Tomoda K, Kubota Y, Kato J. Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1. Nature 1999; 398:160-5.
-
(1999)
Nature
, vol.398
, pp. 160-165
-
-
Tomoda, K.1
Kubota, Y.2
Kato, J.3
-
98
-
-
0034682818
-
Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability
-
Ishida N, Kitagawa M, Hatakeyama S, Nakayama K. Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability. J Biol Chem 2000; 275:25146-54.
-
(2000)
J Biol Chem
, vol.275
, pp. 25146-25154
-
-
Ishida, N.1
Kitagawa, M.2
Hatakeyama, S.3
Nakayama, K.4
-
99
-
-
12544259437
-
Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation
-
Kotake Y, Nakayama K, Ishida N, Nakayama KI. Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation. J Biol Chem 2005; 280:1095-102.
-
(2005)
J Biol Chem
, vol.280
, pp. 1095-1102
-
-
Kotake, Y.1
Nakayama, K.2
Ishida, N.3
Nakayama, K.I.4
-
100
-
-
29944440513
-
Subcellular localization, and tumor suppression stability, Kip1 A pathway in quiescent cells that controls p27
-
Besson A, Gurian-West M, Chen X, Kelly-Spratt KS, Kemp CJ, James M, Roberts JM. Subcellular localization, and tumor suppression stability, Kip1 A pathway in quiescent cells that controls p27. Genes and Dev 2006; 20:47-64.
-
(2006)
Genes and Dev
, vol.20
, pp. 47-64
-
-
Besson, A.1
Gurian-West, M.2
Chen, X.3
Kelly-Spratt, K.S.4
Kemp, C.J.5
James, M.6
Roberts, J.M.7
-
101
-
-
0030997297
-
Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation
-
Alessandrini A, Chiaur DS, Pagano M. Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation. Leukemia 1997; 11:342-5.
-
(1997)
Leukemia
, vol.11
, pp. 342-345
-
-
Alessandrini, A.1
Chiaur, D.S.2
Pagano, M.3
-
102
-
-
0036645678
-
A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression
-
Boehm M, Yoshimoto T, Crook MF, Nallamshetty S, True A, Nabel GJ, Nabel EG. A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression. EMBO J 2002; 21:3390-401.
-
(2002)
EMBO J
, vol.21
, pp. 3390-3401
-
-
Boehm, M.1
Yoshimoto, T.2
Crook, M.F.3
Nallamshetty, S.4
True, A.5
Nabel, G.J.6
Nabel, E.G.7
-
103
-
-
2542489078
-
The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G0 by Mirk/dyrk1B kinase
-
Deng X, Mercer SE, Shah S, Ewton DZ, Friedman E. The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G0 by Mirk/dyrk1B kinase. J Biol Chem 2004; 279:22498-504.
-
(2004)
J Biol Chem
, vol.279
, pp. 22498-22504
-
-
Deng, X.1
Mercer, S.E.2
Shah, S.3
Ewton, D.Z.4
Friedman, E.5
-
104
-
-
34248401210
-
Akt1 sequentially phosphorylates p27kip1 within a conserved but noncanonical region
-
Nacusi LP, Sheaff RJ. Akt1 sequentially phosphorylates p27kip1 within a conserved but noncanonical region. Cell Division 2006; 1:11-38.
-
(2006)
Cell Division
, vol.1
, pp. 11-38
-
-
Nacusi, L.P.1
Sheaff, R.J.2
-
105
-
-
0030925231
-
Cyclin E-CDK2 is a regulator of p27Kip1
-
Sheaff RJ, Groudine M, Gordon M, Roberts JM, Clurman BE. Cyclin E-CDK2 is a regulator of p27Kip1. Genes and Dev 1997; 11:1464-78.
-
(1997)
Genes and Dev
, vol.11
, pp. 1464-1478
-
-
Sheaff, R.J.1
Groudine, M.2
Gordon, M.3
Roberts, J.M.4
Clurman, B.E.5
-
106
-
-
0030847760
-
Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27
-
Vlach J, Hennecke S, Amati B. Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27. EMBO J 1997; 16:5334-44.
-
(1997)
EMBO J
, vol.16
, pp. 5334-5344
-
-
Vlach, J.1
Hennecke, S.2
Amati, B.3
-
107
-
-
0033176887
-
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
-
Carrano AC, Eytan E, Hershko A, Pagano M. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat Cell Biol 1999; 1:193-9.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 193-199
-
-
Carrano, A.C.1
Eytan, E.2
Hershko, A.3
Pagano, M.4
-
108
-
-
0033174070
-
p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells
-
Sutterluty H, Chatelain E, Marti A, Wirbelauer C, Senften M, Muller U, Krek W. p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells. Nat Cell Biol 1999; 1:207-14.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 207-214
-
-
Sutterluty, H.1
Chatelain, E.2
Marti, A.3
Wirbelauer, C.4
Senften, M.5
Muller, U.6
Krek, W.7
-
109
-
-
0033578073
-
p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27
-
Tsvetkov LM, Yeh KH, Lee SJ, Sun H, Zhang H. p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27. Curr Biol 1999; 9:661-4.
-
(1999)
Curr Biol
, vol.9
, pp. 661-664
-
-
Tsvetkov, L.M.1
Yeh, K.H.2
Lee, S.J.3
Sun, H.4
Zhang, H.5
-
110
-
-
0029024015
-
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
-
Pagano M, Tam SW, Theodoras AM, Beer-Romero P, Del Sal G, Chau V, Yew PR, Draetta GF, Rolfe M. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 1995; 269:682-5.
-
(1995)
Science
, vol.269
, pp. 682-685
-
-
Pagano, M.1
Tam, S.W.2
Theodoras, A.M.3
Beer-Romero, P.4
Del Sal, G.5
Chau, V.6
Yew, P.R.7
Draetta, G.F.8
Rolfe, M.9
-
111
-
-
0033553390
-
Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processing
-
Shirane M, Harumiya Y, Ishida N, Hirai A, Miyamoto C, Hatakeyama S, Nakayama K, Kitagawa M. Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processing. J Biol Chem 1999; 274:13886-93.
-
(1999)
J Biol Chem
, vol.274
, pp. 13886-13893
-
-
Shirane, M.1
Harumiya, Y.2
Ishida, N.3
Hirai, A.4
Miyamoto, C.5
Hatakeyama, S.6
Nakayama, K.7
Kitagawa, M.8
-
112
-
-
33846268807
-
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
-
Chu I, Sun J, Arnaout A, Kahn H, Hanna W, Narod S, Sun P, Tan CK, Hengst L, Slingerland J. p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2. Cell 2007; 128:281-94.
-
(2007)
Cell
, vol.128
, pp. 281-294
-
-
Chu, I.1
Sun, J.2
Arnaout, A.3
Kahn, H.4
Hanna, W.5
Narod, S.6
Sun, P.7
Tan, C.K.8
Hengst, L.9
Slingerland, J.10
-
113
-
-
33846321913
-
Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases
-
Grimmler M, Wang Y, Mund T, Cilensek Z, Keidel EM, Waddell MB, Jäkel H, Kullmann M, Kriwacki RW, Hengst L. Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases. Cell 2007; 128:269-80.
-
(2007)
Cell
, vol.128
, pp. 269-280
-
-
Grimmler, M.1
Wang, Y.2
Mund, T.3
Cilensek, Z.4
Keidel, E.M.5
Waddell, M.B.6
Jäkel, H.7
Kullmann, M.8
Kriwacki, R.W.9
Hengst, L.10
-
114
-
-
0042378825
-
Erk 1,2 phosphorylates p27Kip1: Functional evidence for a role in high glucose-induced hypertrophy of mesangial cells
-
Wolf G, Reinking R, Zahner G, Stahl RAK, Shankland SJ. Erk 1,2 phosphorylates p27Kip1: Functional evidence for a role in high glucose-induced hypertrophy of mesangial cells. Diabetologia 2003; 46:1090-9.
-
(2003)
Diabetologia
, vol.46
, pp. 1090-1099
-
-
Wolf, G.1
Reinking, R.2
Zahner, G.3
Stahl, R.A.K.4
Shankland, S.J.5
-
115
-
-
33646248087
-
Retinoic acid induces p27Kip1 nuclear accumulation by modulating its phosphorylation
-
Borriello A, Cucciolla V, Criscuolo M, Indaco S, Oliva A, Giovane A, Bencivenga D, Iolascon A, Zappia V, Della Ragione F. Retinoic acid induces p27Kip1 nuclear accumulation by modulating its phosphorylation. Cancer Res 2006; 66:4240-8.
-
(2006)
Cancer Res
, vol.66
, pp. 4240-4248
-
-
Borriello, A.1
Cucciolla, V.2
Criscuolo, M.3
Indaco, S.4
Oliva, A.5
Giovane, A.6
Bencivenga, D.7
Iolascon, A.8
Zappia, V.9
Della Ragione, F.10
-
117
-
-
0032757489
-
Structure and expression of the gene encoding mouse F-box protein, Fwd2
-
Miura M, Hatakeyama S, Hattori K, Nakayama K. Structure and expression of the gene encoding mouse F-box protein, Fwd2. Genomics 1999; 62:50-8.
-
(1999)
Genomics
, vol.62
, pp. 50-58
-
-
Miura, M.1
Hatakeyama, S.2
Hattori, K.3
Nakayama, K.4
-
118
-
-
10344260649
-
1 phase
-
1 phase. Nat Cell Biol 2004; 6:1229-35.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1229-1235
-
-
Kamura, T.1
Hara, T.2
Matsumoto, M.3
Ishida, N.4
Okumura, F.5
Hatakeyama, S.6
Yoshida, M.7
Nakayama, K.8
Nakayama, K.I.9
-
119
-
-
24044555556
-
Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase
-
Kotoshiba S, Kamura T, Hara T, Ishida N, Nakayama KI. Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase. J Biol Chem 2005; 280:17694-700.
-
(2005)
J Biol Chem
, vol.280
, pp. 17694-17700
-
-
Kotoshiba, S.1
Kamura, T.2
Hara, T.3
Ishida, N.4
Nakayama, K.I.5
-
120
-
-
27144534830
-
1 phase of the cell cycle
-
1 phase of the cell cycle. Mol Cell Biol 2005; 25:9292-303.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 9292-9303
-
-
Hara, T.1
Kamura, T.2
Kotoshiba, S.3
Takahashi, H.4
Fujiwara, K.5
Onoyama, I.6
Shirakawa, M.7
Mizushima, N.8
Nakayama, K.I.9
-
121
-
-
0034625418
-
Mitotic clonal expansion during preadipocyte differentiation: Calpain-mediated sturnover of p27
-
Patel YM, Lane MD. Mitotic clonal expansion during preadipocyte differentiation: Calpain-mediated sturnover of p27. J Biol Chem 2000; 275:17653-60.
-
(2000)
J Biol Chem
, vol.275
, pp. 17653-17660
-
-
Patel, Y.M.1
Lane, M.D.2
-
122
-
-
0038485631
-
MAP kinase-dependent degradation of p27Kip1 by calpains in choroidal melanoma cells: Requirement of p27Kip1 nuclear export
-
Delmas C, Aragou N, Poussard S, Cottin P, Darbon JM, Manenti S. MAP kinase-dependent degradation of p27Kip1 by calpains in choroidal melanoma cells: Requirement of p27Kip1 nuclear export. J Biol Chem 2003; 278:12443-51.
-
(2003)
J Biol Chem
, vol.278
, pp. 12443-12451
-
-
Delmas, C.1
Aragou, N.2
Poussard, S.3
Cottin, P.4
Darbon, J.M.5
Manenti, S.6
|