A mechanism misregulating p27 in tumors discovered in a functional genomic screen

PLoS Genetics

Volumn 3, Issue 12, 2007, Pages 2415-2427

  Garrett Engele, Carrie M ^a,b   Tasch, Michael A ^b,c   Hwang, Harry C ^a   Fero, Matthew L ^a   Perlmutter, Roger M ^b,c,d   Clurman, Bruce E ^a   Roberts, James M ^a,b  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; CDKN1B PROTEIN, MOUSE; IDB3 PROTEIN, MOUSE; INHIBITOR OF DIFFERENTIATION PROTEIN; MESSENGER RNA; PROTEIN KINASE LCK; RNA; SMALL INTERFERING RNA;

ARTICLE; CELL MATURATION; GENE CONTROL; GENE EXPRESSION; GENE IDENTIFICATION; GENE INSERTION; GENE MUTATION; GENE REPRESSION; GENETIC ANALYSIS; GENETIC SCREENING; GENETIC TRANSCRIPTION; LYMPHOMA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; T LYMPHOCYTE; THYMOCYTE; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CYTOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; METABOLISM; MOLONEY LEUKEMIA ONCOVIRUS; MOUSE MUTANT; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PROMOTER REGION; TUMOR CELL LINE; VIROLOGY;

MUS;

ANIMALS; BASE SEQUENCE; CELL DIFFERENTIATION; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P27; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEINS; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); LYMPHOMA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MOLONEY MURINE LEUKEMIA VIRUS; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; RNA, NEOPLASM; RNA, SMALL INTERFERING; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC;

EID: 37749003752     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0030219     Document Type: Article

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