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Volumn 8, Issue 1, 2015, Pages 4-22

The emerging role of miRNAs in inflammatory bowel disease: A review

Author keywords

epigenetics; inflammatory bowel disease; microRNA

Indexed keywords

ANTAGOMIR; MICRORNA; MICRORNA 106A; MICRORNA 126; MICRORNA 155; MICRORNA 192; MICRORNA 200B; MICRORNA 21; MICRORNA 29; NANOPARTICLE; SMALL UNTRANSLATED RNA; UNCLASSIFIED DRUG; VIRUS VECTOR;

EID: 84919493836     PISSN: 1756283X     EISSN: 17562848     Source Type: Journal    
DOI: 10.1177/1756283X14547360     Document Type: Review
Times cited : (139)

References (122)
  • 2
    • 84862993281 scopus 로고    scopus 로고
    • Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma
    • Babar I. Cheng C. Booth C. Liang X. Weidhaas J. Saltzman W. et al. (2012) Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma. Proc Natl Acad Sci U S A 109: E1695–E1704.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. E1695-E1704
    • Babar, I.1    Cheng, C.2    Booth, C.3    Liang, X.4    Weidhaas, J.5    Saltzman, W.6
  • 3
    • 84901193349 scopus 로고    scopus 로고
    • MicroRNA-29c functions as a tumor suppressor by direct targeting oncogenic SIRT 1 in hepatocellular carcinoma
    • Bae H. Noh J. Kim J. Eun J. Jung K. Kim M. et al. (2014) MicroRNA-29c functions as a tumor suppressor by direct targeting oncogenic SIRT 1 in hepatocellular carcinoma. Oncogene 33: 2557–2567.
    • (2014) Oncogene , vol.33 , pp. 2557-2567
    • Bae, H.1    Noh, J.2    Kim, J.3    Eun, J.4    Jung, K.5    Kim, M.6
  • 4
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • Bartel D. (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215–233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.1
  • 5
    • 57349134691 scopus 로고    scopus 로고
    • Chemical modification of siRNAs for in vivo use
    • Behlke M. (2008) Chemical modification of siRNAs for in vivo use. Oligonucleotides 18: 305–319.
    • (2008) Oligonucleotides , vol.18 , pp. 305-319
    • Behlke, M.1
  • 6
    • 77649092427 scopus 로고    scopus 로고
    • Preview. MicroRNAs: from decay to decoy
    • Beitzinger M. Meister G. (2010) Preview. MicroRNAs: from decay to decoy. Cell 140: 612–614.
    • (2010) Cell , vol.140 , pp. 612-614
    • Beitzinger, M.1    Meister, G.2
  • 7
    • 81255214942 scopus 로고    scopus 로고
    • Role of MIR-150-targeting C-MYB in colonic epithelial disruption during dextran sulphate sodium-induced murine experimental colitis and human ulcerative colitis
    • Bian Z. Li L. Cui J. Zhang H. Liu Y. Zhang C. et al. (2011) Role of MIR-150-targeting C-MYB in colonic epithelial disruption during dextran sulphate sodium-induced murine experimental colitis and human ulcerative colitis. J Pathol 225: 544–553.
    • (2011) J Pathol , vol.225 , pp. 544-553
    • Bian, Z.1    Li, L.2    Cui, J.3    Zhang, H.4    Liu, Y.5    Zhang, C.6
  • 8
    • 84993779154 scopus 로고    scopus 로고
    • Micro-RNA expression profiling identifies miR-29b as a relevant pro-fibrogenic factor in Crohn's disease intestinal strictures
    • Proceedings of the 8th Congress of the European Crohn's and Colitis Organisation, Poster presentations: Basic science: P 057
    • Biancheri P. (2013) Micro-RNA expression profiling identifies miR-29b as a relevant pro-fibrogenic factor in Crohn's disease intestinal strictures. In: Proceedings of the 8th Congress of the European Crohn's and Colitis Organisation, Poster presentations: Basic science: P 057:
    • (2013)
    • Biancheri, P.1
  • 9
    • 84884315797 scopus 로고    scopus 로고
    • The intracellular sensor NOD 2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release
    • Brain O. Owens B. Pichulik T. Allan P. Khatamzas E. Leslie A. et al. (2013) The intracellular sensor NOD 2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release. Immunity 39: 521–536.
    • (2013) Immunity , vol.39 , pp. 521-536
    • Brain, O.1    Owens, B.2    Pichulik, T.3    Allan, P.4    Khatamzas, E.5    Leslie, A.6
  • 10
    • 79952134938 scopus 로고    scopus 로고
    • A Synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease
    • Brest P. Lapaquette P. Souidi M. Lebrigand K. Cesaro A. Vouret-Craviari V. et al. (2011) A Synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. Nat Genet 43: 242–245.
    • (2011) Nat Genet , vol.43 , pp. 242-245
    • Brest, P.1    Lapaquette, P.2    Souidi, M.3    Lebrigand, K.4    Cesaro, A.5    Vouret-Craviari, V.6
  • 12
    • 53349177819 scopus 로고    scopus 로고
    • Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases
    • Chen X. Ba Y. Ma L. Cai X. Yin Y. Wang K. et al. (2008) Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 18: 997–1006.
    • (2008) Cell Res , vol.18 , pp. 997-1006
    • Chen, X.1    Ba, Y.2    Ma, L.3    Cai, X.4    Yin, Y.5    Wang, K.6
  • 13
    • 84881542485 scopus 로고    scopus 로고
    • miR-122 targets NOD 2 to decrease intestinal epithelial cell injury in Crohn's disease
    • Chen Y. Wang C. Liu Y. Tang L. Zheng M. Xu C. et al. (2013 a) miR-122 targets NOD 2 to decrease intestinal epithelial cell injury in Crohn's disease. Biochem Biophys Res Commun 438: 133–139.
    • (2013) Biochem Biophys Res Commun , vol.438 , pp. 133-139
    • Chen, Y.1    Wang, C.2    Liu, Y.3    Tang, L.4    Zheng, M.5    Xu, C.6
  • 14
    • 84875878248 scopus 로고    scopus 로고
    • miR-200b inhibits TGF-beta1-induced epithelial-mesenchymal transition and promotes growth of intestinal epithelial cells
    • Chen Y. Xiao Y. Ge W. Zhou K. Wen J. Yan W. et al. (2013 b) miR-200b inhibits TGF-beta1-induced epithelial-mesenchymal transition and promotes growth of intestinal epithelial cells. Cell Death Dis 4: e541.
    • (2013) Cell Death Dis , vol.4 , pp. e541
    • Chen, Y.1    Xiao, Y.2    Ge, W.3    Zhou, K.4    Wen, J.5    Yan, W.6
  • 15
    • 35348914716 scopus 로고    scopus 로고
    • Target protectors reveal dampening and balancing of nodal agonist and antagonist by miR-430
    • Choi W. Giraldez A. Schier A. (2007) Target protectors reveal dampening and balancing of nodal agonist and antagonist by miR-430. Science 318: 271–274.
    • (2007) Science , vol.318 , pp. 271-274
    • Choi, W.1    Giraldez, A.2    Schier, A.3
  • 16
    • 84893656645 scopus 로고    scopus 로고
    • NOD2 expression is regulated by microRNAs in colonic epithelial HCT 116 cells
    • Chuang A. Chuang J. Zhai Z. Wu F. Kwon J. (2014) NOD2 expression is regulated by microRNAs in colonic epithelial HCT 116 cells. Inflamm Bowel Dis 20: 126–135.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 126-135
    • Chuang, A.1    Chuang, J.2    Zhai, Z.3    Wu, F.4    Kwon, J.5
  • 17
    • 84880437626 scopus 로고    scopus 로고
    • miR-20b, miR-98, miR-125b-1*, and let-7e* as new potential diagnostic biomarkers in ulcerative colitis
    • Coskun M. Bjerrum J. Seidelin J. Troelsen J. Olsen J. Nielsen O. (2013) miR-20b, miR-98, miR-125b-1*, and let-7e* as new potential diagnostic biomarkers in ulcerative colitis. World J Gastroenterol 19: 4289–4299.
    • (2013) World J Gastroenterol , vol.19 , pp. 4289-4299
    • Coskun, M.1    Bjerrum, J.2    Seidelin, J.3    Troelsen, J.4    Olsen, J.5    Nielsen, O.6
  • 19
    • 0038606999 scopus 로고    scopus 로고
    • Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
    • Czauderna F. Fechtner M. Dames S. Aygun H. Klippel A. Pronk G. et al. (2003) Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res 31: 2705–2716.
    • (2003) Nucleic Acids Res , vol.31 , pp. 2705-2716
    • Czauderna, F.1    Fechtner, M.2    Dames, S.3    Aygun, H.4    Klippel, A.5    Pronk, G.6
  • 20
    • 79952911456 scopus 로고    scopus 로고
    • In silico analysis of combinatorial microRNA activity reveals target genes and pathways associated with breast cancer metastasis
    • Dombkowski A. Sultana Z. Craig D. Jamil H. (2011) In silico analysis of combinatorial microRNA activity reveals target genes and pathways associated with breast cancer metastasis. Cancer Inform 10: 13–29.
    • (2011) Cancer Inform , vol.10 , pp. 13-29
    • Dombkowski, A.1    Sultana, Z.2    Craig, D.3    Jamil, H.4
  • 21
    • 84857135660 scopus 로고    scopus 로고
    • Genome-wide maps of circulating miRNA biomarkers for ulcerative colitis
    • Duttagupta R. Dirienzo S. Jiang R. Bowers J. Gollub J. Kao J. et al. (2012) Genome-wide maps of circulating miRNA biomarkers for ulcerative colitis. PloS ONE 7: e31241.
    • (2012) PloS ONE , vol.7 , pp. e31241
    • Duttagupta, R.1    Dirienzo, S.2    Jiang, R.3    Bowers, J.4    Gollub, J.5    Kao, J.6
  • 22
    • 77649133970 scopus 로고    scopus 로고
    • miR-328 functions as an RNA decoy to modulate hnRNP e 2 regulation of mrna translation in leukemic blasts
    • Eiring A. Harb J. Neviani P. Garton C. Oaks J. Spizzo R. et al. (2010) miR-328 functions as an RNA decoy to modulate hnRNP e 2 regulation of mrna translation in leukemic blasts. Cell 140: 652–665.
    • (2010) Cell , vol.140 , pp. 652-665
    • Eiring, A.1    Harb, J.2    Neviani, P.3    Garton, C.4    Oaks, J.5    Spizzo, R.6
  • 23
    • 31044453678 scopus 로고    scopus 로고
    • SOCS1 restricts dendritic cells’ ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling
    • Evel-Kabler K. Song X. Aldrich M. Huang X. Chen S. (2006) SOCS1 restricts dendritic cells’ ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling. J Clin Invest 116: 90–100.
    • (2006) J Clin Invest , vol.116 , pp. 90-100
    • Evel-Kabler, K.1    Song, X.2    Aldrich, M.3    Huang, X.4    Chen, S.5
  • 24
    • 78049340862 scopus 로고    scopus 로고
    • Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease
    • Fasseu M. Treton X. Guichard C. Pedruzzi E. Cazals-Hatem D. Richard C. et al. (2010) Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease. PloS ONE 5: e13160.
    • (2010) PloS ONE , vol.5 , pp. e13160
    • Fasseu, M.1    Treton, X.2    Guichard, C.3    Pedruzzi, E.4    Cazals-Hatem, D.5    Richard, C.6
  • 25
    • 77956915352 scopus 로고    scopus 로고
    • miR-126 functions as a tumour suppressor in human gastric cancer
    • Feng R. Chen X. Yu Y. Su L. Yu B. Li J. et al. (2010) miR-126 functions as a tumour suppressor in human gastric cancer. Cancer Lett 298: 50–63.
    • (2010) Cancer Lett , vol.298 , pp. 50-63
    • Feng, R.1    Chen, X.2    Yu, Y.3    Su, L.4    Yu, B.5    Li, J.6
  • 26
    • 84871695308 scopus 로고    scopus 로고
    • Up-regulation of microRNA-126 may contribute to pathogenesis of ulcerative colitis via regulating NF-kappaB inhibitor IkappaBalpha
    • Feng X. Wang H. Ye S. Guan J. Tan W. Cheng S. et al. (2012) Up-regulation of microRNA-126 may contribute to pathogenesis of ulcerative colitis via regulating NF-kappaB inhibitor IkappaBalpha. PloS ONE 7: e52782.
    • (2012) PloS ONE , vol.7 , pp. e52782
    • Feng, X.1    Wang, H.2    Ye, S.3    Guan, J.4    Tan, W.5    Cheng, S.6
  • 27
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • Friedman R. Farh K. Burge C. Bartel D. (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19: 92–105.
    • (2009) Genome Res , vol.19 , pp. 92-105
    • Friedman, R.1    Farh, K.2    Burge, C.3    Bartel, D.4
  • 28
    • 77957361864 scopus 로고    scopus 로고
    • Targeting microRNAs in cancer: rationale, strategies and challenges
    • Garzon R. Marcucci G. Croce C. (2010) Targeting microRNAs in cancer: rationale, strategies and challenges. Nat Rev Drug Discov 9: 775–789.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 775-789
    • Garzon, R.1    Marcucci, G.2    Croce, C.3
  • 29
    • 57749116172 scopus 로고    scopus 로고
    • Coordinated regulation of cell cycle transcripts by P53-inducible microRNAs, miR-192 and miR-215
    • Georges S. Biery M. Kim S. Schelter J. Guo J. Chang A. et al. (2008) Coordinated regulation of cell cycle transcripts by P53-inducible microRNAs, miR-192 and miR-215. Cancer Res 68: 10105–10112.
    • (2008) Cancer Res , vol.68 , pp. 10105-10112
    • Georges, S.1    Biery, M.2    Kim, S.3    Schelter, J.4    Guo, J.5    Chang, A.6
  • 30
    • 33846627302 scopus 로고    scopus 로고
    • A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn's disease in ATG16l1
    • Hampe J. Franke A. Rosenstiel P. Till A. Teuber M. Huse K. et al. (2007) A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn's disease in ATG16l1. Nat Genet 39: 207–211.
    • (2007) Nat Genet , vol.39 , pp. 207-211
    • Hampe, J.1    Franke, A.2    Rosenstiel, P.3    Till, A.4    Teuber, M.5    Huse, K.6
  • 31
    • 78649697501 scopus 로고    scopus 로고
    • miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines
    • Henry J. Park J. Jiang J. Kim J. Nagorney D. Roberts L. et al. (2010) miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines. Biochem Biophys Res Commun 403: 120–125.
    • (2010) Biochem Biophys Res Commun , vol.403 , pp. 120-125
    • Henry, J.1    Park, J.2    Jiang, J.3    Kim, J.4    Nagorney, D.5    Roberts, L.6
  • 32
    • 77957682295 scopus 로고    scopus 로고
    • ATG16l1 and NOD 2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis
    • Homer C. Richmond A. Rebert N. Achkar J. McDonald C. (2010) ATG16l1 and NOD 2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis. Gastroenterology 139: 1630–1641, 1641 e 1631–1632.
    • (2010) Gastroenterology , vol.139 , pp. 1630-1641
    • Homer, C.1    Richmond, A.2    Rebert, N.3    Achkar, J.4    McDonald, C.5
  • 33
    • 37349050790 scopus 로고    scopus 로고
    • The roles of binding site arrangement and combinatorial targeting in microRNA repression of gene expression
    • Hon L. Zhang Z. (2007) The roles of binding site arrangement and combinatorial targeting in microRNA repression of gene expression. Genome Biol 8: R166.
    • (2007) Genome Biol , vol.8 , pp. R166
    • Hon, L.1    Zhang, Z.2
  • 34
    • 84864761391 scopus 로고    scopus 로고
    • Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver
    • Hsu S. Wang B. Kota J. Yu J. Costinean S. Kutay H. et al. (2012) Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. J Clin Invest 122: 2871–2883.
    • (2012) J Clin Invest , vol.122 , pp. 2871-2883
    • Hsu, S.1    Wang, B.2    Kota, J.3    Yu, J.4    Costinean, S.5    Kutay, H.6
  • 35
    • 84904042118 scopus 로고    scopus 로고
    • miR-141 regulates colonic leukocytic trafficking by targeting CXCL12β during murine colitis and human Crohn's disease
    • Huang Z. Shi T. Zhou Q. Shi S. Zhao R. Shi H. et al. (2014) miR-141 regulates colonic leukocytic trafficking by targeting CXCL12β during murine colitis and human Crohn's disease. Gut 63: 1247–1257.
    • (2014) Gut , vol.63 , pp. 1247-1257
    • Huang, Z.1    Shi, T.2    Zhou, Q.3    Shi, S.4    Zhao, R.5    Shi, H.6
  • 36
    • 84880008053 scopus 로고    scopus 로고
    • Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease
    • Iborra M. Bernuzzi F. Correale C. Vetrano S. Fiorino G. Beltran B. et al. (2013) Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease. Clin Exp Immunol 173: 250–258.
    • (2013) Clin Exp Immunol , vol.173 , pp. 250-258
    • Iborra, M.1    Bernuzzi, F.2    Correale, C.3    Vetrano, S.4    Fiorino, G.5    Beltran, B.6
  • 37
    • 41149101523 scopus 로고    scopus 로고
    • microRNAs in the miR-106b family regulate P21/CDKN1a and promote cell cycle progression
    • Ivanovska I. Ball A. Diaz R. Magnus J. Kibukawa M. Schelter J. et al. (2008) microRNAs in the miR-106b family regulate P21/CDKN1a and promote cell cycle progression. Mol Cell Biol 28: 2167–2174.
    • (2008) Mol Cell Biol , vol.28 , pp. 2167-2174
    • Ivanovska, I.1    Ball, A.2    Diaz, R.3    Magnus, J.4    Kibukawa, M.5    Schelter, J.6
  • 39
    • 33847682663 scopus 로고    scopus 로고
    • microRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors
    • Kato M. Zhang J. Wang M. Lanting L. Yuan H. Rossi J. et al. (2007) microRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proc Natl Acad Sci U S A 104: 3432–3437.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3432-3437
    • Kato, M.1    Zhang, J.2    Wang, M.3    Lanting, L.4    Yuan, H.5    Rossi, J.6
  • 40
    • 84903975854 scopus 로고    scopus 로고
    • Lessons from miR-143 / 145: the importance of cell-type localization of miRNAs
    • Kent O. McCall M. Cornish T. Halushka M. (2014) Lessons from miR-143 / 145: the importance of cell-type localization of miRNAs. Nucleic Acids Res 42: 7528–7538.
    • (2014) Nucleic Acids Res , vol.42 , pp. 7528-7538
    • Kent, O.1    McCall, M.2    Cornish, T.3    Halushka, M.4
  • 41
    • 79959216005 scopus 로고    scopus 로고
    • Genetics and pathogenesis of inflammatory bowel disease
    • Khor B. Gardet A. Xavier R. (2011) Genetics and pathogenesis of inflammatory bowel disease. Nature 474: 307–317.
    • (2011) Nature , vol.474 , pp. 307-317
    • Khor, B.1    Gardet, A.2    Xavier, R.3
  • 42
    • 66449136951 scopus 로고    scopus 로고
    • Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
    • Kota J. Chivukula R. O'Donnell K. Wentzel E. Montgomery C. Hwang H. et al. (2009) Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137: 1005–1017.
    • (2009) Cell , vol.137 , pp. 1005-1017
    • Kota, J.1    Chivukula, R.2    O'Donnell, K.3    Wentzel, E.4    Montgomery, C.5    Hwang, H.6
  • 43
    • 84884373262 scopus 로고    scopus 로고
    • microRNA-124 regulates STAT 3 expression and is downregulated in colon tissues of pediatric patients with ulcerative colitis
    • e842.
    • Koukos G. Polytarchou C. Kaplan J. Morley-Fletcher A. Gras-Miralles B. Kokkotou E. et al. (2013) microRNA-124 regulates STAT 3 expression and is downregulated in colon tissues of pediatric patients with ulcerative colitis. Gastroenterology 145: 842–852 e842.
    • (2013) Gastroenterology , vol.145 , pp. 842-852
    • Koukos, G.1    Polytarchou, C.2    Kaplan, J.3    Morley-Fletcher, A.4    Gras-Miralles, B.5    Kokkotou, E.6
  • 45
    • 77952479722 scopus 로고    scopus 로고
    • Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs
    • Krol J. Busskamp V. Markiewicz I. Stadler M. Ribi S. Richter J. et al. (2010) Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs. Cell 141: 618–631.
    • (2010) Cell , vol.141 , pp. 618-631
    • Krol, J.1    Busskamp, V.2    Markiewicz, I.3    Stadler, M.4    Ribi, S.5    Richter, J.6
  • 48
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana M. Rauhut R. Lendeckel W. Tuschl T. (2001) Identification of novel genes coding for small expressed RNAs. Science 294: 853–858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 49
    • 77649194674 scopus 로고    scopus 로고
    • Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly
    • Lapaquette P. Glasser A. Huett A. Xavier R. Darfeuille-Michaud A. (2010) Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly. Cell Microbiol 12: 99–113.
    • (2010) Cell Microbiol , vol.12 , pp. 99-113
    • Lapaquette, P.1    Glasser, A.2    Huett, A.3    Xavier, R.4    Darfeuille-Michaud, A.5
  • 50
    • 79956188277 scopus 로고    scopus 로고
    • Potent and systematic RNAi mediated silencing with single oligonucleotide compounds
    • Lapierre J. Salomon W. Cardia J. Bulock K. Lam J. Stanney W. et al. (2011) Potent and systematic RNAi mediated silencing with single oligonucleotide compounds. RNA 17: 1032–1037.
    • (2011) RNA , vol.17 , pp. 1032-1037
    • Lapierre, J.1    Salomon, W.2    Cardia, J.3    Bulock, K.4    Lam, J.5    Stanney, W.6
  • 51
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene LIN-4 encodes small RNAs with antisense complementarity to LIN-14
    • Lee R. Feinbaum R. Ambros V. (1993) The C. elegans heterochronic gene LIN-4 encodes small RNAs with antisense complementarity to LIN-14. Cell 75: 843–854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.1    Feinbaum, R.2    Ambros, V.3
  • 52
    • 83255194160 scopus 로고    scopus 로고
    • Chemical modification and design of anti-miRNA oligonucleotides
    • Lennox K. Behlke M. (2011) Chemical modification and design of anti-miRNA oligonucleotides. Gene Ther 18: 1111–1120.
    • (2011) Gene Ther , vol.18 , pp. 1111-1120
    • Lennox, K.1    Behlke, M.2
  • 53
    • 78649378267 scopus 로고    scopus 로고
    • MicroRNA functions in stress responses
    • Leung A. Sharp P. (2010) MicroRNA functions in stress responses. Mol Cell 40: 205–215.
    • (2010) Mol Cell , vol.40 , pp. 205-215
    • Leung, A.1    Sharp, P.2
  • 54
    • 33947721625 scopus 로고    scopus 로고
    • miR-181a is an intrinsic modulator of T cell sensitivity and selection
    • Li Q. Chau J. Ebert P. Sylvester G. Min H. Liu G. et al. (2007) miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 129: 147–161.
    • (2007) Cell , vol.129 , pp. 147-161
    • Li, Q.1    Chau, J.2    Ebert, P.3    Sylvester, G.4    Min, H.5    Liu, G.6
  • 55
    • 55749099505 scopus 로고    scopus 로고
    • Distinct microRNA expression profiles in acute myeloid leukemia with common translocations
    • Li Z. Lu J. Sun M. Mi S. Zhang H. Luo R. et al. (2008) Distinct microRNA expression profiles in acute myeloid leukemia with common translocations. Proc Natl Acad Sci U S A 105: 15535–15540.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 15535-15540
    • Li, Z.1    Lu, J.2    Sun, M.3    Mi, S.4    Zhang, H.5    Luo, R.6
  • 56
    • 84897546925 scopus 로고    scopus 로고
    • Novel specific microRNA biomarkers in idiopathic inflammatory bowel disease unrelated to disease activity
    • Lin J. Welker N. Zhao Z. Li Y. Zhang J. Reuss S. et al. (2014) Novel specific microRNA biomarkers in idiopathic inflammatory bowel disease unrelated to disease activity. Mod Pathol 27: 602–608.
    • (2014) Mod Pathol , vol.27 , pp. 602-608
    • Lin, J.1    Welker, N.2    Zhao, Z.3    Li, Y.4    Zhang, J.5    Reuss, S.6
  • 57
    • 0037369649 scopus 로고    scopus 로고
    • Local delivery of adenoviral vectors encoding murine interleukin 10 induces colonic interleukin 10 production and is therapeutic for murine colitis
    • Lindsay J. Ciesielski C. Scheinin T. Brennan F. Hodgson H. (2003) Local delivery of adenoviral vectors encoding murine interleukin 10 induces colonic interleukin 10 production and is therapeutic for murine colitis. Gut 52: 363–369.
    • (2003) Gut , vol.52 , pp. 363-369
    • Lindsay, J.1    Ciesielski, C.2    Scheinin, T.3    Brennan, F.4    Hodgson, H.5
  • 59
    • 77955373730 scopus 로고    scopus 로고
    • miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
    • Liu G. Friggeri A. Yang Y. Milosevic J. Ding Q. Thannickal V. et al. (2010) miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis. J Exp Med 207: 1589–1597.
    • (2010) J Exp Med , vol.207 , pp. 1589-1597
    • Liu, G.1    Friggeri, A.2    Yang, Y.3    Milosevic, J.4    Ding, Q.5    Thannickal, V.6
  • 60
    • 84884619263 scopus 로고    scopus 로고
    • Construction of circular miRNA sponges targeting miR-21 or miR-221 and demonstration of their excellent anticancer effects on malignant melanoma cells
    • Liu Y. Cui H. Wang W. Li L. Wang Z. Yang S. et al. (2013) Construction of circular miRNA sponges targeting miR-21 or miR-221 and demonstration of their excellent anticancer effects on malignant melanoma cells. Int J Biochem Cell Biol 45: 2643–2650.
    • (2013) Int J Biochem Cell Biol , vol.45 , pp. 2643-2650
    • Liu, Y.1    Cui, H.2    Wang, W.3    Li, L.4    Wang, Z.5    Yang, S.6
  • 61
    • 84890786701 scopus 로고    scopus 로고
    • miR106b and miR 93 prevent removal of bacteria from epithelial cells by disrupting ATG16l1-mediated autophagy
    • Lu C. Chen J. Xu H. Zhou X. He Q. Li Y. et al. (2014) miR106b and miR 93 prevent removal of bacteria from epithelial cells by disrupting ATG16l1-mediated autophagy. Gastroenterology 146: 188–199.
    • (2014) Gastroenterology , vol.146 , pp. 188-199
    • Lu, C.1    Chen, J.2    Xu, H.3    Zhou, X.4    He, Q.5    Li, Y.6
  • 62
    • 63349085394 scopus 로고    scopus 로고
    • A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microrna interference
    • Lu Y. Xiao J. Lin H. Bai Y. Luo X. Wang Z. et al. (2009) A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microrna interference. Nucleic Acids Res 37: e24.
    • (2009) Nucleic Acids Res , vol.37 , pp. e24
    • Lu, Y.1    Xiao, J.2    Lin, H.3    Bai, Y.4    Luo, X.5    Wang, Z.6
  • 63
    • 78650117232 scopus 로고    scopus 로고
    • microRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer
    • Majid S. Dar A. Saini S. Yamamura S. Hirata H. Tanaka Y. et al. (2010) microRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer. Cancer 116: 5637–5649.
    • (2010) Cancer , vol.116 , pp. 5637-5649
    • Majid, S.1    Dar, A.2    Saini, S.3    Yamamura, S.4    Hirata, H.5    Tanaka, Y.6
  • 64
    • 84880076939 scopus 로고    scopus 로고
    • Why interleukin-10 supplementation does not work in Crohn's disease patients
    • Marlow G. van Gent Ferguson L. (2013) Why interleukin-10 supplementation does not work in Crohn's disease patients. World J Gastroenterol 19: 3931–3941.
    • (2013) World J Gastroenterol , vol.19 , pp. 3931-3941
    • Marlow, G.1    van Gent Ferguson, L.2
  • 65
    • 84887163882 scopus 로고    scopus 로고
    • Interplays between gut microbiota and gene expression regulation by miRNAs
    • Masotti A. (2012) Interplays between gut microbiota and gene expression regulation by miRNAs. Front Cell Infect Microbiol 2: 137.
    • (2012) Front Cell Infect Microbiol , vol.2 , pp. 137
    • Masotti, A.1
  • 67
    • 50449091647 scopus 로고    scopus 로고
    • Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
    • McCarroll S. Huett A. Kuballa P. Chilewski S. Landry A. Goyette P. et al. (2008) Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet 40: 1107–1112.
    • (2008) Nat Genet , vol.40 , pp. 1107-1112
    • McCarroll, S.1    Huett, A.2    Kuballa, P.3    Chilewski, S.4    Landry, A.5    Goyette, P.6
  • 68
    • 84858379476 scopus 로고    scopus 로고
    • microRNAs in stress signaling and human disease
    • Mendell J. Olson E. (2012) microRNAs in stress signaling and human disease. Cell 148: 1172–1187.
    • (2012) Cell , vol.148 , pp. 1172-1187
    • Mendell, J.1    Olson, E.2
  • 69
    • 34147098413 scopus 로고    scopus 로고
    • Cd8(+) T-cell responses to adeno-associated virus capsid in humans
    • Mingozzi F. Maus M. Hui D. Sabatino D. Murphy S. Rasko J. et al. (2007) Cd8(+) T-cell responses to adeno-associated virus capsid in humans. Nat Med 13: 419–422.
    • (2007) Nat Med , vol.13 , pp. 419-422
    • Mingozzi, F.1    Maus, M.2    Hui, D.3    Sabatino, D.4    Murphy, S.5    Rasko, J.6
  • 71
    • 77953307288 scopus 로고    scopus 로고
    • Environmental risk factors for inflammatory bowel disease
    • Molodecky N. Kaplan G. (2010) Environmental risk factors for inflammatory bowel disease. Gastroenterol Hepatol 6: 339–346.
    • (2010) Gastroenterol Hepatol , vol.6 , pp. 339-346
    • Molodecky, N.1    Kaplan, G.2
  • 72
    • 39149085685 scopus 로고    scopus 로고
    • Tissue distribution of cynomolgus adeno-associated viruses AAV10, AAV11, and AAVCY.7 in naturally infected monkeys
    • Mori S. Takeuchi T. Enomoto Y. Kondo K. Sato K. Ono F. et al. (2008) Tissue distribution of cynomolgus adeno-associated viruses AAV10, AAV11, and AAVCY.7 in naturally infected monkeys. Arch Virol 153: 375–380.
    • (2008) Arch Virol , vol.153 , pp. 375-380
    • Mori, S.1    Takeuchi, T.2    Enomoto, Y.3    Kondo, K.4    Sato, K.5    Ono, F.6
  • 73
    • 79551541594 scopus 로고    scopus 로고
    • The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families
    • Murakami Y. Toyoda H. Tanaka M. Kuroda M. Harada Y. Matsuda F. et al. (2011) The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families. PloS ONE 6: e16081.
    • (2011) PloS ONE , vol.6 , pp. e16081
    • Murakami, Y.1    Toyoda, H.2    Tanaka, M.3    Kuroda, M.4    Harada, Y.5    Matsuda, F.6
  • 74
    • 80052661268 scopus 로고    scopus 로고
    • Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis
    • Murugaiyan G. Beynon V. Mittal A. Joller N. Weiner H. (2011) Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis. J Immunol 187: 2213–2221.
    • (2011) J Immunol , vol.187 , pp. 2213-2221
    • Murugaiyan, G.1    Beynon, V.2    Mittal, A.3    Joller, N.4    Weiner, H.5
  • 76
    • 84892786901 scopus 로고    scopus 로고
    • Crohn's disease-associated adherent invasive Escherichia coli modulate levels of microRNAs in intestinal epithelial cells to reduce autophagy
    • Nguyen H. Dalmasso G. Muller S. Carriere J. Seibold F. Darfeuille-Michaud A. (2014) Crohn's disease-associated adherent invasive Escherichia coli modulate levels of microRNAs in intestinal epithelial cells to reduce autophagy. Gastroenterology 146: 508–519.
    • (2014) Gastroenterology , vol.146 , pp. 508-519
    • Nguyen, H.1    Dalmasso, G.2    Muller, S.3    Carriere, J.4    Seibold, F.5    Darfeuille-Michaud, A.6
  • 77
    • 74049088187 scopus 로고    scopus 로고
    • microRNA-7 modulates CD98 expression during intestinal epithelial cell differentiation
    • Nguyen H. Dalmasso G. Yan Y. Laroui H. Dahan S. Mayer L. et al. (2010) microRNA-7 modulates CD98 expression during intestinal epithelial cell differentiation. J Biol Chem 285: 1479–1489.
    • (2010) J Biol Chem , vol.285 , pp. 1479-1489
    • Nguyen, H.1    Dalmasso, G.2    Yan, Y.3    Laroui, H.4    Dahan, S.5    Mayer, L.6
  • 79
    • 0035978533 scopus 로고    scopus 로고
    • A Frameshift mutation in NOD 2 associated with susceptibility to Crohn's disease
    • Ogura Y. Bonen D. Inohara N. Nicolae D. Chen F. Ramos R. et al. (2001) A Frameshift mutation in NOD 2 associated with susceptibility to Crohn's disease. Nature 411: 603–606.
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1    Bonen, D.2    Inohara, N.3    Nicolae, D.4    Chen, F.5    Ramos, R.6
  • 81
    • 34347338690 scopus 로고    scopus 로고
    • Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
    • Parkes M. Barrett J. Prescott N. Tremelling M. Anderson C. Fisher S. et al. (2007) Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 39: 830–832.
    • (2007) Nat Genet , vol.39 , pp. 830-832
    • Parkes, M.1    Barrett, J.2    Prescott, N.3    Tremelling, M.4    Anderson, C.5    Fisher, S.6
  • 82
    • 0034597777 scopus 로고    scopus 로고
    • Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
    • Pasquinelli A. Reinhart B. Slack F. Martindale M. Kuroda M. Maller B. et al. (2000) Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 408: 86–89.
    • (2000) Nature , vol.408 , pp. 86-89
    • Pasquinelli, A.1    Reinhart, B.2    Slack, F.3    Martindale, M.4    Kuroda, M.5    Maller, B.6
  • 84
    • 38849166053 scopus 로고    scopus 로고
    • Systemic Leukocyte-directed siRNA delivery revealing cyclin D 1 as an anti-inflammatory target
    • Peer D. Park E. Morishita Y. Carman C. Shimaoka M. (2008) Systemic Leukocyte-directed siRNA delivery revealing cyclin D 1 as an anti-inflammatory target. Science 319: 627–630.
    • (2008) Science , vol.319 , pp. 627-630
    • Peer, D.1    Park, E.2    Morishita, Y.3    Carman, C.4    Shimaoka, M.5
  • 85
    • 83555161563 scopus 로고    scopus 로고
    • miR-143 and miR-145 are downregulated in ulcerative colitis: putative regulators of inflammation and protooncogenes
    • Pekow J. Dougherty U. Mustafi R. Zhu H. Kocherginsky M. Rubin D. et al. (2012) miR-143 and miR-145 are downregulated in ulcerative colitis: putative regulators of inflammation and protooncogenes. Inflamm Bowel Dis 18: 94–100.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 94-100
    • Pekow, J.1    Dougherty, U.2    Mustafi, R.3    Zhu, H.4    Kocherginsky, M.5    Rubin, D.6
  • 86
    • 84882797818 scopus 로고    scopus 로고
    • Targeting translational control as a novel way to treat inflammatory disease: the emerging role of microRNAs
    • Plank M. Maltby S. Mattes J. Foster P. (2013) Targeting translational control as a novel way to treat inflammatory disease: the emerging role of microRNAs. Clin Exp Allergy 43: 981–999.
    • (2013) Clin Exp Allergy , vol.43 , pp. 981-999
    • Plank, M.1    Maltby, S.2    Mattes, J.3    Foster, P.4
  • 87
    • 84856206687 scopus 로고    scopus 로고
    • Identification of adeno-associated viral vectors suitable for intestinal gene delivery and modulation of experimental colitis
    • Polyak S. Mach A. Porvasnik S. Dixon L. Conlon T. Erger K. et al. (2012) Identification of adeno-associated viral vectors suitable for intestinal gene delivery and modulation of experimental colitis. Am J Physiol Gastrointest Liver Physiol 302: G296–G308.
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.302 , pp. G296-G308
    • Polyak, S.1    Mach, A.2    Porvasnik, S.3    Dixon, L.4    Conlon, T.5    Erger, K.6
  • 88
    • 84858807419 scopus 로고    scopus 로고
    • Serological antibodies in inflammatory bowel disease: a systematic review
    • Prideaux L. de Cruz P. Ng S. Kamm M. (2012) Serological antibodies in inflammatory bowel disease: a systematic review. Inflamm Bowel Dis 18: 1340–1355.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 1340-1355
    • Prideaux, L.1    de Cruz, P.2    Ng, S.3    Kamm, M.4
  • 89
    • 84859464569 scopus 로고    scopus 로고
    • Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies
    • Pritchard C. Kroh E. Wood B. Arroyo J. Dougherty K. Miyaji M. et al. (2012) Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies. Cancer Prev Res 5: 492–497.
    • (2012) Cancer Prev Res , vol.5 , pp. 492-497
    • Pritchard, C.1    Kroh, E.2    Wood, B.3    Arroyo, J.4    Dougherty, K.5    Miyaji, M.6
  • 90
    • 78751476297 scopus 로고    scopus 로고
    • Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis
    • Roderburg C. Urban G. Bettermann K. Vucur M. Zimmermann H. Schmidt S. et al. (2011) Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis. Hepatology 53: 209–218.
    • (2011) Hepatology , vol.53 , pp. 209-218
    • Roderburg, C.1    Urban, G.2    Bettermann, K.3    Vucur, M.4    Zimmermann, H.5    Schmidt, S.6
  • 91
    • 84871701834 scopus 로고    scopus 로고
    • Ustekinumab induction and maintenance therapy in refractory Crohn's disease
    • Sandborn W. Gasink C. Gao L. Blank M. Johanns J. Guzzo C. et al. (2012) Ustekinumab induction and maintenance therapy in refractory Crohn's disease. N Engl J Med 367: 1519–1528.
    • (2012) N Engl J Med , vol.367 , pp. 1519-1528
    • Sandborn, W.1    Gasink, C.2    Gao, L.3    Blank, M.4    Johanns, J.5    Guzzo, C.6
  • 93
    • 84879476666 scopus 로고    scopus 로고
    • microRNA-21 knockout improve the survival rate in DSS induced fatal colitis through protecting against inflammation and tissue injury
    • Shi C. Liang Y. Yang J. Xia Y. Chen H. Han H. et al. (2013) microRNA-21 knockout improve the survival rate in DSS induced fatal colitis through protecting against inflammation and tissue injury. PloS ONE 8: e66814.
    • (2013) PloS ONE , vol.8 , pp. e66814
    • Shi, C.1    Liang, Y.2    Yang, J.3    Xia, Y.4    Chen, H.5    Han, H.6
  • 94
    • 77649275761 scopus 로고    scopus 로고
    • Novel RNA-based strategies for therapeutic gene silencing
    • Sibley C. Seow Y. Wood M. (2010) Novel RNA-based strategies for therapeutic gene silencing. Mol Ther 18: 466–476.
    • (2010) Mol Ther , vol.18 , pp. 466-476
    • Sibley, C.1    Seow, Y.2    Wood, M.3
  • 95
    • 33748506089 scopus 로고    scopus 로고
    • Human IRGM Induces autophagy to eliminate intracellular mycobacteria
    • Singh S. Davis A. Taylor G. Deretic V. (2006) Human IRGM Induces autophagy to eliminate intracellular mycobacteria. Science 313: 1438–1441.
    • (2006) Science , vol.313 , pp. 1438-1441
    • Singh, S.1    Davis, A.2    Taylor, G.3    Deretic, V.4
  • 96
    • 77956392147 scopus 로고    scopus 로고
    • miR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4
    • e581–520.
    • Sonkoly E. Janson P. Majuri M. Savinko T. Fyhrquist N. Eidsmo L. et al. (2010) miR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4. J Allergy Clin Immunol 126: 581–589 e581–520.
    • (2010) J Allergy Clin Immunol , vol.126 , pp. 581-589
    • Sonkoly, E.1    Janson, P.2    Majuri, M.3    Savinko, T.4    Fyhrquist, N.5    Eidsmo, L.6
  • 98
    • 47949106374 scopus 로고    scopus 로고
    • Epidemiology of inflammatory bowel disease in a German twin cohort: results of a nationwide study
    • Spehlmann M. Begun A. Burghardt J. Lepage P. Raedler A. Schreiber S. (2008) Epidemiology of inflammatory bowel disease in a German twin cohort: results of a nationwide study. Inflamm Bowel Dis 14: 968–976.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 968-976
    • Spehlmann, M.1    Begun, A.2    Burghardt, J.3    Lepage, P.4    Raedler, A.5    Schreiber, S.6
  • 99
    • 42449156220 scopus 로고    scopus 로고
    • Altered expression of microRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis
    • Stanczyk J. Pedrioli D. Brentano F. Sanchez-Pernaute O. Kolling C. Gay R. et al. (2008) Altered expression of microRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. Arthritis Rheum 58: 1001–1009.
    • (2008) Arthritis Rheum , vol.58 , pp. 1001-1009
    • Stanczyk, J.1    Pedrioli, D.2    Brentano, F.3    Sanchez-Pernaute, O.4    Kolling, C.5    Gay, R.6
  • 100
    • 84868518061 scopus 로고    scopus 로고
    • Apolipoprotein B synthesis inhibition with mipomersen in heterozygous familial hypercholesterolemia: results of a randomized, double-blind, placebo-controlled trial to assess efficacy and safety as add-on therapy in patients with coronary artery disease
    • Stein E. Dufour R. Gagne C. Gaudet D. East C. Donovan J. et al. (2012) Apolipoprotein B synthesis inhibition with mipomersen in heterozygous familial hypercholesterolemia: results of a randomized, double-blind, placebo-controlled trial to assess efficacy and safety as add-on therapy in patients with coronary artery disease. Circulation 126: 2283–2292.
    • (2012) Circulation , vol.126 , pp. 2283-2292
    • Stein, E.1    Dufour, R.2    Gagne, C.3    Gaudet, D.4    East, C.5    Donovan, J.6
  • 101
    • 77951579490 scopus 로고    scopus 로고
    • Increased expression of microRNA in the inflamed colonic mucosa of patients with active ulcerative colitis
    • Suppl 1
    • Takagi T. Naito Y. Mizushima K. Hirata I. Yagi N. Tomatsuri N. et al. (2010) Increased expression of microRNA in the inflamed colonic mucosa of patients with active ulcerative colitis. J Gastroenterol Hepatol 25 Suppl 1: S129–S133.
    • (2010) J Gastroenterol Hepatol , vol.25 , pp. S129-S133
    • Takagi, T.1    Naito, Y.2    Mizushima, K.3    Hirata, I.4    Yagi, N.5    Tomatsuri, N.6
  • 102
    • 57749168828 scopus 로고    scopus 로고
    • microRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
    • Thum T. Gross C. Fiedler J. Fischer T. Kissler S. Bussen M. et al. (2008) microRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 456: 980–984.
    • (2008) Nature , vol.456 , pp. 980-984
    • Thum, T.1    Gross, C.2    Fiedler, J.3    Fischer, T.4    Kissler, S.5    Bussen, M.6
  • 103
    • 84890262634 scopus 로고    scopus 로고
    • Diagnosis and treatment of indeterminate colitis
    • Tremaine W. (2011) Diagnosis and treatment of indeterminate colitis. Gastroenterol Hepatol 7: 826–828.
    • (2011) Gastroenterol Hepatol , vol.7 , pp. 826-828
    • Tremaine, W.1
  • 104
    • 84864773072 scopus 로고    scopus 로고
    • microRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
    • Tsai W. Hsu S. Hsu C. Lai T. Chen S. Shen R. et al. (2012) microRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. J Clin Invest 122: 2884–2897.
    • (2012) J Clin Invest , vol.122 , pp. 2884-2897
    • Tsai, W.1    Hsu, S.2    Hsu, C.3    Lai, T.4    Chen, S.5    Shen, R.6
  • 105
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: microRNAs can up-regulate translation
    • Vasudevan S. Tong Y. Steitz J. (2007) Switching from repression to activation: microRNAs can up-regulate translation. Science 318: 1931–1934.
    • (2007) Science , vol.318 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.3
  • 107
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene LIN-14 by LIN-4 mediates temporal pattern formation in C. elegans
    • Wightman B. Ha I. Ruvkun G. (1993) Posttranscriptional regulation of the heterochronic gene LIN-14 by LIN-4 mediates temporal pattern formation in C. elegans. Cell 75: 855–862.
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 109
    • 68649086358 scopus 로고    scopus 로고
    • Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of C / EBP beta and down-regulation of G-CSF
    • Worm J. Stenvang J. Petri A. Frederiksen K. Obad S. Elmen J. et al. (2009) Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of C / EBP beta and down-regulation of G-CSF. Nucleic Acids Res 37: 5784–5792.
    • (2009) Nucleic Acids Res , vol.37 , pp. 5784-5792
    • Worm, J.1    Stenvang, J.2    Petri, A.3    Frederiksen, K.4    Obad, S.5    Elmen, J.6
  • 110
    • 78650119948 scopus 로고    scopus 로고
    • Peripheral blood microRNAs distinguish active ulcerative colitis and Crohn's disease
    • Wu F. Guo N. Tian H. Marohn M. Gearhart S. Bayless T. et al. (2011) Peripheral blood microRNAs distinguish active ulcerative colitis and Crohn's disease. Inflamm Bowel Dis 17: 241–250.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 241-250
    • Wu, F.1    Guo, N.2    Tian, H.3    Marohn, M.4    Gearhart, S.5    Bayless, T.6
  • 111
    • 78649231641 scopus 로고    scopus 로고
    • Identification of microRNAs associated with ileal and colonic Crohn's disease
    • Wu F. Zhang S. Dassopoulos T. Harris M. Bayless T. Meltzer S. et al. (2010) Identification of microRNAs associated with ileal and colonic Crohn's disease. Inflamm Bowel Dis 16: 1729–1738.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 1729-1738
    • Wu, F.1    Zhang, S.2    Dassopoulos, T.3    Harris, M.4    Bayless, T.5    Meltzer, S.6
  • 112
    • 55249119513 scopus 로고    scopus 로고
    • microRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha
    • e1624.
    • Wu F. Zikusoka M. Trindade A. Dassopoulos T. Harris M. Bayless T. et al. (2008) microRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha. Gastroenterology 135: 1624–1635 e1624.
    • (2008) Gastroenterology , vol.135 , pp. 1624-1635
    • Wu, F.1    Zikusoka, M.2    Trindade, A.3    Dassopoulos, T.4    Harris, M.5    Bayless, T.6
  • 114
    • 33745085925 scopus 로고    scopus 로고
    • Short hairpin RNA-expressing bacteria elicit RNA interference in mammals
    • Xiang S. Fruehauf J. Li C. (2006) Short hairpin RNA-expressing bacteria elicit RNA interference in mammals. Nat Biotechnol 24: 697–702.
    • (2006) Nat Biotechnol , vol.24 , pp. 697-702
    • Xiang, S.1    Fruehauf, J.2    Li, C.3
  • 115
    • 84878193012 scopus 로고    scopus 로고
    • Overexpression of miR-21 in patients with ulcerative colitis impairs intestinal epithelial barrier function through targeting the Rho GTPase Rho B
    • Yang Y. Ma Y. Shi C. Chen H. Zhang H. Chen N. et al. (2013) Overexpression of miR-21 in patients with ulcerative colitis impairs intestinal epithelial barrier function through targeting the Rho GTPase Rho B. Biochem Biophys Res Commun 434: 746–752.
    • (2013) Biochem Biophys Res Commun , vol.434 , pp. 746-752
    • Yang, Y.1    Ma, Y.2    Shi, C.3    Chen, H.4    Zhang, H.5    Chen, N.6
  • 117
    • 80053380337 scopus 로고    scopus 로고
    • Identification of a microRNA signature in renal fibrosis: role of miR-21
    • Zarjou A. Yang S. Abraham E. Agarwal A. Liu G. (2011) Identification of a microRNA signature in renal fibrosis: role of miR-21. Am J Physiol Renal Physiol 301: F793–F801.
    • (2011) Am J Physiol Renal Physiol , vol.301 , pp. F793-F801
    • Zarjou, A.1    Yang, S.2    Abraham, E.3    Agarwal, A.4    Liu, G.5
  • 118
    • 84888217213 scopus 로고    scopus 로고
    • miR-106b fine tunes ATG16l1 expression and autophagic activity in intestinal epithelial HCT 116 cells
    • Zhai Z. Wu F. Chuang A. Kwon J. (2013) miR-106b fine tunes ATG16l1 expression and autophagic activity in intestinal epithelial HCT 116 cells. Inflamm Bowel Dis 19: 2295–2301.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 2295-2301
    • Zhai, Z.1    Wu, F.2    Chuang, A.3    Kwon, J.4
  • 119
    • 84896992207 scopus 로고    scopus 로고
    • Human autophagy gene ATG16L1 is post-transcriptionally regulated by MIR142-3p
    • Zhai Z. Wu F. Dong F. Chuang A. Messer J. Boone D. et al. (2014) Human autophagy gene ATG16L1 is post-transcriptionally regulated by MIR142-3p. Autophagy 10: 468–479.
    • (2014) Autophagy , vol.10 , pp. 468-479
    • Zhai, Z.1    Wu, F.2    Dong, F.3    Chuang, A.4    Messer, J.5    Boone, D.6
  • 120
    • 58149291298 scopus 로고    scopus 로고
    • Reversal of HIV-1 latency with anti-microRNA inhibitors
    • Zhang H. (2009) Reversal of HIV-1 latency with anti-microRNA inhibitors. Int J Biochem Cell Biol 41: 451–454.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 451-454
    • Zhang, H.1


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