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Volumn 8, Issue 6, 2013, Pages

MicroRNA-21 Knockout Improve the Survival Rate in DSS Induced Fatal Colitis through Protecting against Inflammation and Tissue Injury

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD68 ANTIGEN; CYCLIN D1; DEXTRAN SULFATE; HEMOGLOBIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; MICRORNA 21; PROTEIN CDC42; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84879476666     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066814     Document Type: Article
Times cited : (137)

References (43)
  • 2
    • 77956339881 scopus 로고    scopus 로고
    • OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma
    • Medina PP, Nolde M, Slack FJ, (2010) OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature 467: 86-90.
    • (2010) Nature , vol.467 , pp. 86-90
    • Medina, P.P.1    Nolde, M.2    Slack, F.J.3
  • 3
    • 57749168828 scopus 로고    scopus 로고
    • MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
    • Thum T, Gross C, Fiedler J, Fischer T, Kissler S, et al. (2008) MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 456: 980-984.
    • (2008) Nature , vol.456 , pp. 980-984
    • Thum, T.1    Gross, C.2    Fiedler, J.3    Fischer, T.4    Kissler, S.5
  • 4
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, et al. (2008) MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27: 2128-2136.
    • (2008) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5
  • 5
    • 40249092910 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
    • Zhu S, Wu H, Wu F, Nie D, Sheng S, et al. (2008) MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 18: 350-359.
    • (2008) Cell Res , vol.18 , pp. 350-359
    • Zhu, S.1    Wu, H.2    Wu, F.3    Nie, D.4    Sheng, S.5
  • 6
    • 55249119513 scopus 로고    scopus 로고
    • MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha
    • e1624
    • Wu F, Zikusoka M, Trindade A, Dassopoulos T, Harris ML, et al. (2008) MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha. Gastroenterology 135: 1624-1635 e1624.
    • (2008) Gastroenterology , vol.135 , pp. 1624-1635
    • Wu, F.1    Zikusoka, M.2    Trindade, A.3    Dassopoulos, T.4    Harris, M.L.5
  • 7
    • 77951579490 scopus 로고    scopus 로고
    • Increased expression of microRNA in the inflamed colonic mucosa of patients with active ulcerative colitis
    • Takagi T, Naito Y, Mizushima K, Hirata I, Yagi N, et al. (2010) Increased expression of microRNA in the inflamed colonic mucosa of patients with active ulcerative colitis. J Gastroenterol Hepatol 25Suppl 1: S129-133.
    • (2010) J Gastroenterol Hepatol , vol.25
    • Takagi, T.1    Naito, Y.2    Mizushima, K.3    Hirata, I.4    Yagi, N.5
  • 8
    • 78649231641 scopus 로고    scopus 로고
    • Identification of microRNAs associated with ileal and colonic Crohn's disease
    • Wu F, Zhang S, Dassopoulos T, Harris ML, Bayless TM, et al. (2010) Identification of microRNAs associated with ileal and colonic Crohn's disease. Inflamm Bowel Dis 16: 1729-1738.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 1729-1738
    • Wu, F.1    Zhang, S.2    Dassopoulos, T.3    Harris, M.L.4    Bayless, T.M.5
  • 9
    • 52649097493 scopus 로고    scopus 로고
    • Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis
    • Noble CL, Abbas AR, Cornelius J, Lees CW, Ho GT, et al. (2008) Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis. Gut 57: 1398-1405.
    • (2008) Gut , vol.57 , pp. 1398-1405
    • Noble, C.L.1    Abbas, A.R.2    Cornelius, J.3    Lees, C.W.4    Ho, G.T.5
  • 10
    • 77951803595 scopus 로고    scopus 로고
    • Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets
    • Mesko B, Poliska S, Szegedi A, Szekanecz Z, Palatka K, et al. (2010) Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets. BMC Med Genomics 3: 15.
    • (2010) BMC Med Genomics , vol.3 , pp. 15
    • Mesko, B.1    Poliska, S.2    Szegedi, A.3    Szekanecz, Z.4    Palatka, K.5
  • 11
    • 0037216498 scopus 로고    scopus 로고
    • Increased expression of interleukin 17 in inflammatory bowel disease
    • Fujino S, Andoh A, Bamba S, Ogawa A, Hata K, et al. (2003) Increased expression of interleukin 17 in inflammatory bowel disease. Gut 52: 65-70.
    • (2003) Gut , vol.52 , pp. 65-70
    • Fujino, S.1    Andoh, A.2    Bamba, S.3    Ogawa, A.4    Hata, K.5
  • 12
    • 65249106172 scopus 로고    scopus 로고
    • MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression
    • Lu TX, Munitz A, Rothenberg ME, (2009) MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression. J Immunol 182: 4994-5002.
    • (2009) J Immunol , vol.182 , pp. 4994-5002
    • Lu, T.X.1    Munitz, A.2    Rothenberg, M.E.3
  • 13
  • 14
    • 67651098994 scopus 로고    scopus 로고
    • MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation
    • Hashimi ST, Fulcher JA, Chang MH, Gov L, Wang S, et al. (2009) MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation. Blood 114: 404-414.
    • (2009) Blood , vol.114 , pp. 404-414
    • Hashimi, S.T.1    Fulcher, J.A.2    Chang, M.H.3    Gov, L.4    Wang, S.5
  • 15
    • 84864279381 scopus 로고    scopus 로고
    • Inductive microRNA-21 impairs anti-mycobacterial responses by targeting IL-12 and Bcl-2
    • Wu Z, Lu H, Sheng J, Li L, (2012) Inductive microRNA-21 impairs anti-mycobacterial responses by targeting IL-12 and Bcl-2. FEBS Lett 586: 2459-2467.
    • (2012) FEBS Lett , vol.586 , pp. 2459-2467
    • Wu, Z.1    Lu, H.2    Sheng, J.3    Li, L.4
  • 16
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM, Kosik KS, (2005) MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65: 6029-6033.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 17
    • 77953782181 scopus 로고    scopus 로고
    • MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligand
    • Sayed D, He M, Hong C, Gao S, Rane S, et al. (2010) MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligand. J Biol Chem 285: 20281-20290.
    • (2010) J Biol Chem , vol.285 , pp. 20281-20290
    • Sayed, D.1    He, M.2    Hong, C.3    Gao, S.4    Rane, S.5
  • 18
    • 77950282576 scopus 로고    scopus 로고
    • MicroRNA-21 is upregulated during the proliferative phase of liver regeneration, targets Pellino-1, and inhibits NF-kappaB signaling
    • Marquez RT, Wendlandt E, Galle CS, Keck K, McCaffrey AP, (2010) MicroRNA-21 is upregulated during the proliferative phase of liver regeneration, targets Pellino-1, and inhibits NF-kappaB signaling. Am J Physiol Gastrointest Liver Physiol 298: G535-541.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.298
    • Marquez, R.T.1    Wendlandt, E.2    Galle, C.S.3    Keck, K.4    McCaffrey, A.P.5
  • 19
    • 84857822685 scopus 로고    scopus 로고
    • A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration
    • Ng R, Song G, Roll GR, Frandsen NM, Willenbring H, (2012) A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration. J Clin Invest 122: 1097-1108.
    • (2012) J Clin Invest , vol.122 , pp. 1097-1108
    • Ng, R.1    Song, G.2    Roll, G.R.3    Frandsen, N.M.4    Willenbring, H.5
  • 20
    • 70350214454 scopus 로고    scopus 로고
    • microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells
    • Wang P, Zou F, Zhang X, Li H, Dulak A, et al. (2009) microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells. Cancer Res 69: 8157-8165.
    • (2009) Cancer Res , vol.69 , pp. 8157-8165
    • Wang, P.1    Zou, F.2    Zhang, X.3    Li, H.4    Dulak, A.5
  • 21
    • 84866376633 scopus 로고    scopus 로고
    • MicroRNA-21 Modulates the Levels of Reactive Oxygen Species Levels by Targeting SOD3 and TNFα
    • Zhang X, Ng WL, Wang P, Tian L, Werner E, et al. (2012) MicroRNA-21 Modulates the Levels of Reactive Oxygen Species Levels by Targeting SOD3 and TNFα. Cancer Res 72(18): 4707-4713.
    • (2012) Cancer Res , vol.72 , Issue.18 , pp. 4707-4713
    • Zhang, X.1    Ng, W.L.2    Wang, P.3    Tian, L.4    Werner, E.5
  • 22
    • 37349059288 scopus 로고    scopus 로고
    • In situ detection of precursor and mature microRNAs in paraffin embedded, formalin fixed tissues and cell preparations
    • Nuovo GJ, (2008) In situ detection of precursor and mature microRNAs in paraffin embedded, formalin fixed tissues and cell preparations. Methods 44: 39-46.
    • (2008) Methods , vol.44 , pp. 39-46
    • Nuovo, G.J.1
  • 23
    • 84875988471 scopus 로고    scopus 로고
    • MiR-145 and miR-143 regulate odontoblast differentiation through targeting Klf4 and Osx in a feedback loop
    • Liu H, Lin H, Zhang L, Sun Q, Yuan G, et al. (2013) MiR-145 and miR-143 regulate odontoblast differentiation through targeting Klf4 and Osx in a feedback loop. J Biol Chem 288(13): 9261-9271.
    • (2013) J Biol Chem , vol.288 , Issue.13 , pp. 9261-9271
    • Liu, H.1    Lin, H.2    Zhang, L.3    Sun, Q.4    Yuan, G.5
  • 24
    • 33947622744 scopus 로고    scopus 로고
    • Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism
    • Smith P, Mangan NE, Walsh CM, Fallon RE, McKenzie AN, et al. (2007) Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism. J Immunol 178: 4557-4566.
    • (2007) J Immunol , vol.178 , pp. 4557-4566
    • Smith, P.1    Mangan, N.E.2    Walsh, C.M.3    Fallon, R.E.4    McKenzie, A.N.5
  • 25
    • 46049083963 scopus 로고    scopus 로고
    • Unique role of junctional adhesion molecule-a in maintaining mucosal homeostasis in inflammatory bowel disease
    • Vetrano S, Rescigno M, Cera MR, Correale C, Rumio C, et al. (2008) Unique role of junctional adhesion molecule-a in maintaining mucosal homeostasis in inflammatory bowel disease. Gastroenterology 135: 173-184.
    • (2008) Gastroenterology , vol.135 , pp. 173-184
    • Vetrano, S.1    Rescigno, M.2    Cera, M.R.3    Correale, C.4    Rumio, C.5
  • 26
    • 34249801207 scopus 로고    scopus 로고
    • Angiogenesis blockade as a new therapeutic approach to experimental colitis
    • Danese S, Sans M, Spencer DM, Beck I, Donate F, et al. (2007) Angiogenesis blockade as a new therapeutic approach to experimental colitis. Gut 56: 855-862.
    • (2007) Gut , vol.56 , pp. 855-862
    • Danese, S.1    Sans, M.2    Spencer, D.M.3    Beck, I.4    Donate, F.5
  • 27
    • 34447119424 scopus 로고    scopus 로고
    • Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease
    • Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, et al. (2007) Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease. J Clin Invest 117: 1951-1960.
    • (2007) J Clin Invest , vol.117 , pp. 1951-1960
    • Scaldaferri, F.1    Sans, M.2    Vetrano, S.3    Graziani, C.4    De Cristofaro, R.5
  • 28
    • 0036950810 scopus 로고    scopus 로고
    • Collagen-binding integrin alpha1beta1 regulates intestinal inflammation in experimental colitis
    • Krieglstein CF, Cerwinka WH, Sprague AG, Laroux FS, Grisham MB, et al. (2002) Collagen-binding integrin alpha1beta1 regulates intestinal inflammation in experimental colitis. J Clin Invest 110: 1773-1782.
    • (2002) J Clin Invest , vol.110 , pp. 1773-1782
    • Krieglstein, C.F.1    Cerwinka, W.H.2    Sprague, A.G.3    Laroux, F.S.4    Grisham, M.B.5
  • 29
    • 65249099918 scopus 로고    scopus 로고
    • Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability
    • Cani PD, Possemiers S, Van de Wiele T, Guiot Y, Everard A, et al. (2009) Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. Gut 58: 1091-1103.
    • (2009) Gut , vol.58 , pp. 1091-1103
    • Cani, P.D.1    Possemiers, S.2    Van de Wiele, T.3    Guiot, Y.4    Everard, A.5
  • 30
    • 9644302527 scopus 로고    scopus 로고
    • Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis
    • Karhausen J, Furuta GT, Tomaszewski JE, Johnson RS, Colgan SP, et al. (2004) Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis. J Clin Invest 114: 1098-1106.
    • (2004) J Clin Invest , vol.114 , pp. 1098-1106
    • Karhausen, J.1    Furuta, G.T.2    Tomaszewski, J.E.3    Johnson, R.S.4    Colgan, S.P.5
  • 31
    • 84859587965 scopus 로고    scopus 로고
    • Neuronal guidance molecule netrin-1 attenuates inflammatory cell trafficking during acute experimental colitis
    • Aherne CM, Collins CB, Masterson JC, Tizzano M, Boyle TA, et al. (2012) Neuronal guidance molecule netrin-1 attenuates inflammatory cell trafficking during acute experimental colitis. Gut 61(5): 695-705.
    • (2012) Gut , vol.61 , Issue.5 , pp. 695-705
    • Aherne, C.M.1    Collins, C.B.2    Masterson, J.C.3    Tizzano, M.4    Boyle, T.A.5
  • 33
    • 82755189251 scopus 로고    scopus 로고
    • Selective upregulation of microRNA expression in peripheral blood leukocytes in IL-10-/- mice precedes expression in the colon
    • Schaefer JS, Montufar-Solis D, Vigneswaran N, Klein JR, (2011) Selective upregulation of microRNA expression in peripheral blood leukocytes in IL-10-/- mice precedes expression in the colon. J Immunol 187: 5834-5841.
    • (2011) J Immunol , vol.187 , pp. 5834-5841
    • Schaefer, J.S.1    Montufar-Solis, D.2    Vigneswaran, N.3    Klein, J.R.4
  • 34
    • 58249085437 scopus 로고    scopus 로고
    • Regulation of intestinal barrier function by signal transducer and activator of transcription 5b
    • Han X, Ren X, Jurickova I, Groschwitz K, Pasternak BA, et al. (2009) Regulation of intestinal barrier function by signal transducer and activator of transcription 5b. Gut 58: 49-58.
    • (2009) Gut , vol.58 , pp. 49-58
    • Han, X.1    Ren, X.2    Jurickova, I.3    Groschwitz, K.4    Pasternak, B.A.5
  • 35
    • 75649113377 scopus 로고    scopus 로고
    • Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
    • Sheedy FJ, Palsson-McDermott E, Hennessy EJ, Martin C, O'Leary JJ, et al. (2010) Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat Immunol 11: 141-147.
    • (2010) Nat Immunol , vol.11 , pp. 141-147
    • Sheedy, F.J.1    Palsson-McDermott, E.2    Hennessy, E.J.3    Martin, C.4    O'Leary, J.J.5
  • 37
    • 0037434790 scopus 로고    scopus 로고
    • Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
    • Etienne-Manneville S, Hall A, (2003) Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity. Nature 421: 753-756.
    • (2003) Nature , vol.421 , pp. 753-756
    • Etienne-Manneville, S.1    Hall, A.2
  • 38
    • 2342432240 scopus 로고    scopus 로고
    • Cdc42-the centre of polarity
    • Etienne-Manneville S, (2004) Cdc42-the centre of polarity. J Cell Sci 117: 1291-1300.
    • (2004) J Cell Sci , vol.117 , pp. 1291-1300
    • Etienne-Manneville, S.1
  • 39
    • 84863393793 scopus 로고    scopus 로고
    • Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice
    • Sakamori R, Das S, Yu S, Feng S, Stypulkowski E, et al. (2012) Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice. J Clin Invest 122: 1052-1065.
    • (2012) J Clin Invest , vol.122 , pp. 1052-1065
    • Sakamori, R.1    Das, S.2    Yu, S.3    Feng, S.4    Stypulkowski, E.5
  • 40
    • 68349131301 scopus 로고    scopus 로고
    • The S. Typhimurium effector SopE induces caspase-1 activation in stromal cells to initiate gut inflammation
    • Muller AJ, Hoffmann C, Galle M, Van Den Broeke A, Heikenwalder M, et al. (2009) The S. Typhimurium effector SopE induces caspase-1 activation in stromal cells to initiate gut inflammation. Cell Host Microbe 6: 125-136.
    • (2009) Cell Host Microbe , vol.6 , pp. 125-136
    • Muller, A.J.1    Hoffmann, C.2    Galle, M.3    Van Den Broeke, A.4    Heikenwalder, M.5
  • 41
    • 79952535412 scopus 로고    scopus 로고
    • Enteric glia protect against Shigella flexneri invasion in intestinal epithelial cells: a role for S-nitrosoglutathione
    • Flamant M, Aubert P, Rolli-Derkinderen M, Bourreille A, Neunlist MR, et al. (2011) Enteric glia protect against Shigella flexneri invasion in intestinal epithelial cells: a role for S-nitrosoglutathione. Gut 60: 473-484.
    • (2011) Gut , vol.60 , pp. 473-484
    • Flamant, M.1    Aubert, P.2    Rolli-Derkinderen, M.3    Bourreille, A.4    Neunlist, M.R.5
  • 42
    • 84864705032 scopus 로고    scopus 로고
    • The signaling pathway of Campylobacter jejuni-induced Cdc42 activation: Role of fibronectin, integrin beta1, tyrosine kinases and guanine exchange factor Vav2
    • Krause-Gruszczynska M, Boehm M, Rohde M, Tegtmeyer N, Takahashi S, et al. (2011) The signaling pathway of Campylobacter jejuni-induced Cdc42 activation: Role of fibronectin, integrin beta1, tyrosine kinases and guanine exchange factor Vav2. Cell Commun Signal 9: 32.
    • (2011) Cell Commun Signal , vol.9 , pp. 32
    • Krause-Gruszczynska, M.1    Boehm, M.2    Rohde, M.3    Tegtmeyer, N.4    Takahashi, S.5
  • 43
    • 84878193012 scopus 로고    scopus 로고
    • Overexpression of miR-21 in patients with ulcerative colitis impairs intestinal epithelial barrier function through targeting the Rho GTPase RhoB
    • Yang Y, Ma Y, Shi C, Chen H, Zhang H, et al. (2013) Overexpression of miR-21 in patients with ulcerative colitis impairs intestinal epithelial barrier function through targeting the Rho GTPase RhoB. Biochem Biophys Res Commun 434(4): 746-752.
    • (2013) Biochem Biophys Res Commun , vol.434 , Issue.4 , pp. 746-752
    • Yang, Y.1    Ma, Y.2    Shi, C.3    Chen, H.4    Zhang, H.5


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