5α-reductase type i expression is downregulated in the prefrontal cortex/Brodmann's area 9 (BA9) of depressed patients

Psychopharmacology

Volumn 231, Issue 17, 2014, Pages 3569-3580

  Agis Balboa, Roberto Carlos ^a,b   Guidotti, Alessandro ^a   Pinna, Graziano ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b Hospital Meixoeiro Edificio Anexo   (Spain)

Author keywords

5 reductase type I; Allopregnanolone; GABAA receptor; Major unipolar depression; Selective brain steroidogenic stimulants (SBSSs)

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; MESSENGER RNA; NEURON SPECIFIC ENOLASE; NEUROSTEROID; SEROTONIN UPTAKE INHIBITOR; STEROID 5ALPHA REDUCTASE 1; TRICYCLIC ANTIDEPRESSANT AGENT; ELTANOLONE; STEROID 5ALPHA REDUCTASE; STEROID-5ALPHA-REDUCTASE TYPE 1;

ADULT; ARTICLE; BRODMANN AREA 9; CEREBELLUM; CEREBROSPINAL FLUID LEVEL; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DEPRESSION; DOWN REGULATION; FEMALE; GABAERGIC TRANSMISSION; HORMONE SYNTHESIS; HUMAN; HUMAN TISSUE; MALE; MIDDLE AGED; PILOT STUDY; PREFRONTAL CORTEX; TISSUE DISTRIBUTION; YOUNG ADULT; BIOSYNTHESIS; CEREBROSPINAL FLUID; ENZYMOLOGY; GENETICS; HEALTH CARE FACILITY; MAJOR DEPRESSION; PYRAMIDAL NERVE CELL; SUICIDE;

3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; ADULT; DEPRESSIVE DISORDER, MAJOR; DOWN-REGULATION; FEMALE; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS; PREFRONTAL CORTEX; PREGNANOLONE; PYRAMIDAL CELLS; RNA, MESSENGER; SUICIDE; TISSUE BANKS; YOUNG ADULT;

EID: 84918839738     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-014-3567-5     Document Type: Article

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