Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 47, 2007, Pages 18736-18741

  Agís Balboa, Roberto C ^a   Pinna, Graziano ^a   Pibiri, Fabio ^a   Kadriu, Bashkim ^a   Costa, Erminio ^a   Guidotti, Alessandro ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

5 reductase; Aggression; Allopregnanolone; Amygdala; Glutamatergic neurons

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 3ALPHA HYDROXYSTEROID DEHYDROGENASE; 4 AMINOBUTYRIC ACID RECEPTOR; NEUROSTEROID; STEROID 5ALPHA REDUCTASE; STEROID 5ALPHA REDUCTASE 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DENTATE GYRUS; DOWN REGULATION; HIPPOCAMPUS; IN SITU HYBRIDIZATION; INTERNEURON; LIMBIC CORTEX; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOCIAL BEHAVIOR; SOCIAL ISOLATION; STEROIDOGENESIS; THALAMUS NUCLEUS;

3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (B-SPECIFIC); ANIMALS; BEHAVIOR, ANIMAL; BRAIN; DOWN-REGULATION; IN SITU HYBRIDIZATION; MALE; MICE; NEURONS; POLYMERASE CHAIN REACTION; RNA, MESSENGER; SOCIAL ISOLATION; STEROIDS; TESTOSTERONE 5-ALPHA-REDUCTASE;

BALBOA; MUS;

EID: 36749048035     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0709419104     Document Type: Article

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