-
2
-
-
0027332117
-
Brain 5α-reductase: Cellular, enzymatic, and molecular perspectives and implications for biological function
-
LEPHART, E.D. 1993. Brain 5α-reductase: cellular, enzymatic, and molecular perspectives and implications for biological function. Mol. Cell Neurosci. 4: 473-484.
-
(1993)
Mol. Cell Neurosci.
, vol.4
, pp. 473-484
-
-
Lephart, E.D.1
-
3
-
-
0028267115
-
Brain aromatization of androgens
-
NAFTOLIN, F. 1994. Brain aromatization of androgens. J. Reprod. Med. 39: 257-261.
-
(1994)
J. Reprod. Med.
, vol.39
, pp. 257-261
-
-
Naftolin, F.1
-
4
-
-
0003106545
-
Neurosteroids: From definition and biochemistry to physiopathologic function
-
E.E. Baulieu, P. Robel & M. Schumacher, Eds.: Humana Press. Totowa, NJ
-
ROBEL, P., M. SCHUMACHER & E.E. BAULIEU. 1999. Neurosteroids: from definition and biochemistry to physiopathologic function. In Neurosteroids. A New Regulatory Function in the Nervous System. E.E. Baulieu, P. Robel & M. Schumacher, Eds.: 1-25. Humana Press. Totowa, NJ.
-
(1999)
Neurosteroids. A New Regulatory Function in the Nervous System
, pp. 1-25
-
-
Robel, P.1
Schumacher, M.2
Baulieu, E.E.3
-
5
-
-
0026509649
-
A receptor: Mechanism of action and physiological significance
-
A receptor: mechanism of action and physiological significance. Prog. Neurobiol. 38: 379-395.
-
(1992)
Prog. Neurobiol.
, vol.38
, pp. 379-395
-
-
Majewska, M.D.1
-
6
-
-
0028003285
-
Neurosteroids: Biochemistry, modes of action, and clinical relevance
-
MELLON, S. 1994. Neurosteroids: biochemistry, modes of action, and clinical relevance. J. Clin. Endocrinol. Metab. 78: 1003-1008.
-
(1994)
J. Clin. Endocrinol. Metab.
, vol.78
, pp. 1003-1008
-
-
Mellon, S.1
-
7
-
-
0016590015
-
The formation of estrogens by central neuroendocrine tissues
-
NAFTOLIN, F., K.J. RYAN, I.J. DAVIES, et al. 1975. The formation of estrogens by central neuroendocrine tissues. Rec. Prog. Horm. Res. 31: 295-319.
-
(1975)
Rec. Prog. Horm. Res.
, vol.31
, pp. 295-319
-
-
Naftolin, F.1
Ryan, K.J.2
Davies, I.J.3
-
8
-
-
0345160562
-
Human cholesterol side-chain cleavage enzyme, P450SCC: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta
-
CHUNG, B.C., K.J. MATTESON, R. VOUTILAINEN, et al. 1986. Human cholesterol side-chain cleavage enzyme, P450SCC: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta. Proc. Natl. Acad. Sci. USA 83: 8962-8966.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 8962-8966
-
-
Chung, B.C.1
Matteson, K.J.2
Voutilainen, R.3
-
10
-
-
0029064861
-
Cholesterol side-chain cleavage cytochrome P450 gene expression in the primitive gut of the mouse embryo does not require steroidogenic factor 1
-
KEENEY, D.S., Y. IKEDA, M.R. WATERMAN, et al. 1995. Cholesterol side-chain cleavage cytochrome P450 gene expression in the primitive gut of the mouse embryo does not require steroidogenic factor 1. Mol. Endocrinol. 9: 1091-1098.
-
(1995)
Mol. Endocrinol.
, vol.9
, pp. 1091-1098
-
-
Keeney, D.S.1
Ikeda, Y.2
Waterman, M.R.3
-
11
-
-
0027381252
-
Neurosteroid biosynthesis: Genes for adrenal steroidogenic enzymes are expressed in the brain
-
MELLON, S. & C.F. DESCHEPPER. 1993. Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain. Brain Res. 629: 283-292.
-
(1993)
Brain Res.
, vol.629
, pp. 283-292
-
-
Mellon, S.1
Deschepper, C.F.2
-
12
-
-
0029118238
-
Cytochrome P450 in the brain: Neuroendocrine functions
-
WARNER, M. & J.-A. GUSTAFSSON. 1995. Cytochrome P450 in the brain: neuroendocrine functions. Front. Neuroendocrinol. 16: 224-236.
-
(1995)
Front. Neuroendocrinol.
, vol.16
, pp. 224-236
-
-
Warner, M.1
Gustafsson, J.-A.2
-
13
-
-
0032722444
-
Sex- and age-specific differences in human brain CYP11A1 mRNA expression
-
WATZKA, M., F. BIDLINGMAIER, J. SCHRAMM, et al. 1999. Sex-and age-specific differences in human brain CYP11A1 mRNA expression. J. Neuroendocrinol. 11: 901-905.
-
(1999)
J. Neuroendocrinol.
, vol.11
, pp. 901-905
-
-
Watzka, M.1
Bidlingmaier, F.2
Schramm, J.3
-
14
-
-
0033615255
-
Expression of cytochrome P450scc mRNA in the hippocampus of patients with temporal lobe epilepsy
-
BEYENBURG, S., B. STOFFEL-WAGNER, M. WATZKA, et al. 1999. Expression of cytochrome P450scc mRNA in the hippocampus of patients with temporal lobe epilepsy. NeuroReport 10: 3067-3070.
-
(1999)
NeuroReport
, vol.10
, pp. 3067-3070
-
-
Beyenburg, S.1
Stoffel-Wagner, B.2
Watzka, M.3
-
15
-
-
0029085085
-
Expression of cytochrome P450 side-chain cleavage enzyme and 3beta-hydroxysteroid dehydrogenase in the rat central nervous system: A study by polymerase chain reaction and in situ hybridization
-
SANNE, J.L. & K.E. KRUEGER. 1995. Expression of cytochrome P450 side-chain cleavage enzyme and 3beta-hydroxysteroid dehydrogenase in the rat central nervous system: a study by polymerase chain reaction and in situ hybridization. J. Neurochem. 65: 528-536.
-
(1995)
J. Neurochem.
, vol.65
, pp. 528-536
-
-
Sanne, J.L.1
Krueger, K.E.2
-
16
-
-
0032504559
-
Age- and region-specific expressions of the messenger RNAs encoding for steroidogenic enzymes p450SCC, p450c17 and 3beta-HSD in the postnatal rat brain
-
KOHCHI, C., K. UKENA & K. TSUTSUI. 1998. Age-and region-specific expressions of the messenger RNAs encoding for steroidogenic enzymes p450SCC, p450c17 and 3beta-HSD in the postnatal rat brain. Brain Res. 801: 233-238.
-
(1998)
Brain Res.
, vol.801
, pp. 233-238
-
-
Kohchi, C.1
Ukena, K.2
Tsutsui, K.3
-
17
-
-
0004238525
-
Neurosteroids: Oligodendrocyte mitochondria convert cholesterol to pregnenolone
-
HU, Z.Y., E. BOURREAU, I. JUNG-TESTAS, et al. 1987. Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone. Proc. Natl. Acad. Sci. USA 84: 8215-8219.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 8215-8219
-
-
Hu, Z.Y.1
Bourreau, E.2
Jung-Testas, I.3
-
18
-
-
0006656956
-
Isolation of a full-length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in non-steroidogenic cells
-
CORBIN, J.C., S. GRAHAM-LORENCE, M.J. MCPHAUL, et al. 1988. Isolation of a full-length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in non-steroidogenic cells. Proc. Natl. Acad. Sci. USA 85: 8948-8953.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 8948-8953
-
-
Corbin, J.C.1
Graham-Lorence, S.2
McPhaul, M.J.3
-
19
-
-
0023691843
-
Cloning of a comparative cDNA encoding human aromatase: Immunochemical identification and sequence analysis
-
HARADA, N. 1988. Cloning of a comparative cDNA encoding human aromatase: immunochemical identification and sequence analysis. Biochem. Biophys. Res. Commun. 156: 725-732.
-
(1988)
Biochem. Biophys. Res. Commun.
, vol.156
, pp. 725-732
-
-
Harada, N.1
-
21
-
-
0015183023
-
Aromatization of androstenedione by limbic system tissue from human foetuses
-
NAFTOLIN, F., K.J. RYAN & Z. PETRO. 1971. Aromatization of androstenedione by limbic system tissue from human foetuses. J. Endocrinol. 51: 795-796.
-
(1971)
J. Endocrinol.
, vol.51
, pp. 795-796
-
-
Naftolin, F.1
Ryan, K.J.2
Petro, Z.3
-
22
-
-
0024835332
-
Aromatase in human fetal tissues
-
DOODY, K.J. & B.R. CARR. 1989. Aromatase in human fetal tissues. Am. J. Obstet. Gynecol. 161: 1694-1697.
-
(1989)
Am. J. Obstet. Gynecol.
, vol.161
, pp. 1694-1697
-
-
Doody, K.J.1
Carr, B.R.2
-
23
-
-
0032076991
-
Neuroblastoma and Alzheimer's disease brain cells contain aromatase activity
-
WOZNIAK, A., R.E. HUTCHINSON, C.M. MORRIS, et al. 1998. Neuroblastoma and Alzheimer's disease brain cells contain aromatase activity. Steroids 63: 263-267.
-
(1998)
Steroids
, vol.63
, pp. 263-267
-
-
Wozniak, A.1
Hutchinson, R.E.2
Morris, C.M.3
-
24
-
-
0032746272
-
Expression of CYP19 (aromatase) mRNA in different areas of the human brain
-
STOFFEL-WAGNER, B., M. WATZKA, J. SCHRAMM, et al. 1999. Expression of CYP19 (aromatase) mRNA in different areas of the human brain. J. Steroid Biochem. Mol. Biol. 70: 237-241.
-
(1999)
J. Steroid Biochem. Mol. Biol.
, vol.70
, pp. 237-241
-
-
Stoffel-Wagner, B.1
Watzka, M.2
Schramm, J.3
-
26
-
-
0033306888
-
Characterization of aromatase cytochrome P450 activity in the human temporal lobe
-
STECKELBROECK, S., D. HEIDRICH, B. STOFFEL-WAGNER, et al. 1999 Characterization of aromatase cytochrome P450 activity in the human temporal lobe. J. Clin. Endocrinol. Metab. 84: 2795-2801.
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 2795-2801
-
-
Steckelbroeck, S.1
Heidrich, D.2
Stoffel-Wagner, B.3
-
27
-
-
0022550064
-
1-Methyl-1,4-androstadiene-3,17-dione (SH 489): Characterization of an irreversible inhibitor of estrogen biosynthesis
-
HENDERSON, D., G. NORBISRATH & U. KERB. 1986. 1-Methyl-1,4- androstadiene-3,17-dione (SH 489): characterization of an irreversible inhibitor of estrogen biosynthesis. J. Steroid Biochem. 24: 303-306.
-
(1986)
J. Steroid Biochem.
, vol.24
, pp. 303-306
-
-
Henderson, D.1
Norbisrath, G.2
Kerb, U.3
-
28
-
-
0019736999
-
Aromatization of androstenedione by human adipose tissue stromal cells in monolayer culture
-
ACKERMAN, G.E., M.E. SMITH, C.R. MENDELSON, et al. 1981. Aromatization of androstenedione by human adipose tissue stromal cells in monolayer culture. J. Clin. Endocrinol. Metab. 53: 412-417.
-
(1981)
J. Clin. Endocrinol. Metab.
, vol.53
, pp. 412-417
-
-
Ackerman, G.E.1
Smith, M.E.2
Mendelson, C.R.3
-
29
-
-
0025981129
-
Comparison of aromatase activity in human prostatic, testicular and placental tissues
-
ROWLANDS, M.G., J.H. DAVIES, R.J. SHEARER, et al. 1991. Comparison of aromatase activity in human prostatic, testicular and placental tissues. J. Enzyme Inhib. 4: 307-313.
-
(1991)
J. Enzyme Inhib.
, vol.4
, pp. 307-313
-
-
Rowlands, M.G.1
Davies, J.H.2
Shearer, R.J.3
-
30
-
-
0025303307
-
Structural and biochemical properties of cloned and expressed human and rat steroid 5α-reductases
-
ANDERSSON, S. & D.W. RUSSELL. 1990. Structural and biochemical properties of cloned and expressed human and rat steroid 5α-reductases. Proc. Natl. Acad. Sci. USA 87: 3640-3644.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 3640-3644
-
-
Andersson, S.1
Russell, D.W.2
-
31
-
-
0026055914
-
Deletion of steroid 5α-reductase 2 gene in male pseudohermaphroditism
-
ANDERSSON, S., D.M. BERMAN, E.P. JENKINS, et al. 1991. Deletion of steroid 5α-reductase 2 gene in male pseudohermaphroditism. Nature 354: 159-161.
-
(1991)
Nature
, vol.354
, pp. 159-161
-
-
Andersson, S.1
Berman, D.M.2
Jenkins, E.P.3
-
32
-
-
0020470292
-
The 5α-reduction of testosterone in the neuroendocrine structures: Biochemical and physiological implications
-
MARTINI, L. 1982. The 5α-reduction of testosterone in the neuroendocrine structures: biochemical and physiological implications. Endocr. Rev. 3: 1-25.
-
(1982)
Endocr. Rev.
, vol.3
, pp. 1-25
-
-
Martini, L.1
-
33
-
-
0030992888
-
Regional distribution of cytosolic and particulate α- dihydroprogesterone 3α-hydroxysteroid oxidoreductases in female rat brain
-
LI, X., P.J. BERTICS & H.J. KARAVOLAS. 1997. Regional distribution of cytosolic and particulate α-dihydroprogesterone 3α- hydroxysteroid oxidoreductases in female rat brain. J. Steroid Biochem. Mol. Biol. 60: 311-318.
-
(1997)
J. Steroid Biochem. Mol. Biol.
, vol.60
, pp. 311-318
-
-
Li, X.1
Bertics, P.J.2
Karavolas, H.J.3
-
34
-
-
0020448947
-
A study of 5α-reductase in human fetal brain
-
SAITOH, H., K. HIRATO, T. YANAIHARA, et al. 1982. A study of 5α-reductase in human fetal brain. Endocrinol. Jpn. 29: 461-467.
-
(1982)
Endocrinol. Jpn.
, vol.29
, pp. 461-467
-
-
Saitoh, H.1
Hirato, K.2
Yanaihara, T.3
-
35
-
-
0017265757
-
Steroid metabolism in foetal tissues. IV. Conversion of testosterone to 5α-dihydrotestosterone in human foetal brain
-
SCHINDLER, A.E. 1976. Steroid metabolism in foetal tissues. IV. Conversion of testosterone to 5α-dihydrotestosterone in human foetal brain. J. Steroid Biochem. 7: 97-100.
-
(1976)
J. Steroid Biochem.
, vol.7
, pp. 97-100
-
-
Schindler, A.E.1
-
36
-
-
0015339775
-
Metabolism of 4-14C-progesterone and 4-14-C-testosterone in brain of the previable human fetus
-
MICKAN, H. 1972. Metabolism of 4-14C-progesterone and 4-14-C-testosterone in brain of the previable human fetus. Steroids 19: 659-668.
-
(1972)
Steroids
, vol.19
, pp. 659-668
-
-
Mickan, H.1
-
37
-
-
0017624809
-
Metabolism of [14C]testosterone by human foetal and adult brain tissue
-
JENKINS, J.S. & C.J. HALL. 1977. Metabolism of [14C]testosterone by human foetal and adult brain tissue. J. Endocrinol. 74: 425-429.
-
(1977)
J. Endocrinol.
, vol.74
, pp. 425-429
-
-
Jenkins, J.S.1
Hall, C.J.2
-
38
-
-
0022999074
-
A comparative study of the metabolism of testosterone in the neuroendocrine structures of several animal species
-
CELOTTI, F., R.C. MELCANGI, P. NEGRI-CESI, et al. 1986. A comparative study of the metabolism of testosterone in the neuroendocrine structures of several animal species. Neuroendocrinol. Lett. 5: 227-236.
-
(1986)
Neuroendocrinol. Lett.
, vol.5
, pp. 227-236
-
-
Celotti, F.1
Melcangi, R.C.2
Negri-Cesi, P.3
-
39
-
-
0031596229
-
Expression of 5α-reductase in the human temporal lobe of children and adults
-
STOFFEL-WAGNER, B., M. WATZKA, S. STECKELBROECK, et al. 1998. Expression of 5α-reductase in the human temporal lobe of children and adults. J. Clin. Endocrinol. Metab. 83: 3636-3642.
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, pp. 3636-3642
-
-
Stoffel-Wagner, B.1
Watzka, M.2
Steckelbroeck, S.3
-
40
-
-
0033622151
-
Expression of 5α-reductase and 3α-hydroxisteroid oxidoreductase in the hippocampus of patients with chronic temporal lobe epilepsy
-
STOFFEL-WAGNER, B., S. BEYENBURG, M. WATZKA, et al. 2000. Expression of 5α-reductase and 3α-hydroxisteroid oxidoreductase in the hippocampus of patients with chronic temporal lobe epilepsy. Epilepsia 41: 140-147.
-
(2000)
Epilepsia
, vol.41
, pp. 140-147
-
-
Stoffel-Wagner, B.1
Beyenburg, S.2
Watzka, M.3
-
41
-
-
0027234897
-
Tissue distribution and ontogeny of steroid 5α-reductase isoenzyme expression
-
THIGPEN, A.E., R.I. SILVER, J.M. GUILEYARDO, et al. 1993. Tissue distribution and ontogeny of steroid 5α-reductase isoenzyme expression. J. Clin. Invest. 92: 903-910.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 903-910
-
-
Thigpen, A.E.1
Silver, R.I.2
Guileyardo, J.M.3
-
42
-
-
0026723090
-
Tissue distribution and kinetic characteristics of rat steroid 5α-reductase isozymes
-
NORMINGTON, K. & D.W. RUSSELL. 1992. Tissue distribution and kinetic characteristics of rat steroid 5α-reductase isozymes. J. Biol. Chem. 267: 19548-19554.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 19548-19554
-
-
Normington, K.1
Russell, D.W.2
-
43
-
-
0034744568
-
Characterization of the 5α-reductase-3α-hydroxysteroid dehydrogenase complex in the human brain
-
STECKELBROECK, S., M. WATZKA, R. REICHELT, et al. 2001. Characterization of the 5α-reductase-3α-hydroxysteroid dehydrogenase complex in the human brain. J. Clin. Endocrinol. Metab. 86: 1324-1331.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1324-1331
-
-
Steckelbroeck, S.1
Watzka, M.2
Reichelt, R.3
-
44
-
-
0002466064
-
Conversion of testosterone into 5a-reduced metabolites in the anterior pituitary and in the brain of maturing rats
-
MASSA, R., S. JUSTO & L. MARTINI. 1975. Conversion of testosterone into 5a-reduced metabolites in the anterior pituitary and in the brain of maturing rats. J. Steroid Biochem. 19: 235-239.
-
(1975)
J. Steroid Biochem.
, vol.19
, pp. 235-239
-
-
Massa, R.1
Justo, S.2
Martini, L.3
-
45
-
-
0017623284
-
Aromatization and 5α-reduction of androgens in discrete hypothalamic and limbic regions of the male and female rat
-
SELMANOFF, M.K., L.D. BRODKIN, R.I. WEINER, et al. 1977. Aromatization and 5α-reduction of androgens in discrete hypothalamic and limbic regions of the male and female rat. Endocrinology 101: 841-848.
-
(1977)
Endocrinology
, vol.101
, pp. 841-848
-
-
Selmanoff, M.K.1
Brodkin, L.D.2
Weiner, R.I.3
-
46
-
-
0027769784
-
Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3α-hydroxysteroid dehydrogenase
-
QIN, K.N., M.I. NEW & K.C. CHENG. 1993. Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3α-hydroxysteroid dehydrogenase. J Steroid Biochem. Mol. Biol. 52: 141-147.
-
(1993)
J Steroid Biochem. Mol. Biol.
, vol.52
, pp. 141-147
-
-
Qin, K.N.1
New, M.I.2
Cheng, K.C.3
-
47
-
-
0029091370
-
Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3α-hydroxisteroid dehydrogenases
-
KHANNA, M., K.-N. QIN, R.W. WANG, et al. 1995. Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3α-hydroxisteroid dehydrogenases. J. Biol. Chem. 270: 20162-20168.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20162-20168
-
-
Khanna, M.1
Qin, K.-N.2
Wang, R.W.3
-
48
-
-
0029103278
-
Distribution of 3alpha-hydroxysteroid dehydrogenase in rat brain and molecular cloning of multiple cDNAs encoding structurally related proteins in humans
-
KHANNA, M., K.N. QIN & K.-C. CHENG. 1995. Distribution of 3alpha-hydroxysteroid dehydrogenase in rat brain and molecular cloning of multiple cDNAs encoding structurally related proteins in humans. J. Steroid Biochem. Mol. Biol. 53: 41-46.
-
(1995)
J. Steroid Biochem. Mol. Biol.
, vol.53
, pp. 41-46
-
-
Khanna, M.1
Qin, K.N.2
Cheng, K.-C.3
-
49
-
-
0030925341
-
Molecular endocrinology of hydroxisteroid dehydrogenases
-
PENNING, T.M. 1997. Molecular endocrinology of hydroxisteroid dehydrogenases. Endocr. Rev. 18: 281-305.
-
(1997)
Endocr. Rev.
, vol.18
, pp. 281-305
-
-
Penning, T.M.1
-
50
-
-
0034287545
-
Human 3α-hydroxisteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: Functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones
-
PENNING, T.M., M.E. BURCZYNSKI, J.M. JEZ, et al. 2000. Human 3α-hydroxisteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones. Biochem. J. 351: 61-77.
-
(2000)
Biochem. J.
, vol.351
, pp. 61-77
-
-
Penning, T.M.1
Burczynski, M.E.2
Jez, J.M.3
-
51
-
-
0032586817
-
17β-hydroxisteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) familiy; nomenclature and main characteristics of the 17HSD/KSR enzymes
-
PELTOKETO, H., V. LUU-THE & J. SIMARD. 1999 17β-hydroxisteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) familiy; nomenclature and main characteristics of the 17HSD/KSR enzymes. J. Mol. Endocrinol. 23: 1-11.
-
(1999)
J. Mol. Endocrinol.
, vol.23
, pp. 1-11
-
-
Peltoketo, H.1
Luu-The, V.2
Simard, J.3
-
52
-
-
0032727093
-
Determination of cDNA, gene structure and chromosomal localization of the novel 17β-hyxdroxysteroid dehydrogenase type 7
-
KRAZEISEN, A., R. BREITLING, K. IMAI, et al. 1999. Determination of cDNA, gene structure and chromosomal localization of the novel 17β- hyxdroxysteroid dehydrogenase type 7. FEBS Lett. 460: 373-379.
-
(1999)
FEBS Lett.
, vol.460
, pp. 373-379
-
-
Krazeisen, A.1
Breitling, R.2
Imai, K.3
-
53
-
-
0031023049
-
A key role of 17β-hydroxisteroid dehydrogenases in sex steroid biology
-
LABRIE, F., V. LUU-THE, S.X. LIN, et al. 1997. A key role of 17β-hydroxisteroid dehydrogenases in sex steroid biology. Steroids 62: 148-158.
-
(1997)
Steroids
, vol.62
, pp. 148-158
-
-
Labrie, F.1
Luu-The, V.2
Lin, S.X.3
-
54
-
-
0027932285
-
Widespread tissue distribution of steroid sulfatase, 3β- hydroxisteroid dehydrogenase/D5-D4 isomerase (3β-HSD), 17β-HSD, 5α-reductase and aromatase activities in the rhesus monkey
-
MARTEL, C., M.H. MELNER, D. GAGNÉ, et al. 1994. Widespread tissue distribution of steroid sulfatase, 3β-hydroxisteroid dehydrogenase/D5-D4 isomerase (3β-HSD), 17β-HSD, 5α-reductase and aromatase activities in the rhesus monkey. Mol. Cell. Endocrinol. 104: 103-111.
-
(1994)
Mol. Cell. Endocrinol.
, vol.104
, pp. 103-111
-
-
Martel, C.1
Melner, M.H.2
Gagné, D.3
-
55
-
-
0014599347
-
Testosterone metabolism in target tissues: Hypothalamic and pituitary tissues of the adult rat and human fetus, and the immature rat epiphysis
-
JAFFE, R.B. 1969. Testosterone metabolism in target tissues: hypothalamic and pituitary tissues of the adult rat and human fetus, and the immature rat epiphysis. Steroids 14: 483-498.
-
(1969)
Steroids
, vol.14
, pp. 483-498
-
-
Jaffe, R.B.1
-
56
-
-
0025259281
-
17β-hydroxysteroid oxidoreductases of human fetal and adult tissues: Immunological cross-reactivity with an anti-human placental cytosolic 17β-hydroxysteroid oxidoreductase antibody
-
MILEWICH, L., B.R. CARR & R.A. FRENKEL. 1990. 17β- hydroxysteroid oxidoreductases of human fetal and adult tissues: immunological cross-reactivity with an anti-human placental cytosolic 17β-hydroxysteroid oxidoreductase antibody. Placenta 11: 95-108.
-
(1990)
Placenta
, vol.11
, pp. 95-108
-
-
Milewich, L.1
Carr, B.R.2
Frenkel, R.A.3
-
57
-
-
0032589909
-
D. Expression of 17β-hydroxysteroid dehydrogenase types 1, 2, 3 and 4 in the human temporal lobe
-
STOFFEL-WAGNER, B., M. WATZKA, S. STECKELBROECK, et al. 1999. D. Expression of 17β-hydroxysteroid dehydrogenase types 1, 2, 3 and 4 in the human temporal lobe. J. Endocrinol. 160: 119-126.
-
(1999)
J. Endocrinol.
, vol.160
, pp. 119-126
-
-
Stoffel-Wagner, B.1
Watzka, M.2
Steckelbroeck, S.3
-
58
-
-
0035931121
-
Expression of 17β-hydroxysteroid dehydrogenase type 5 mRNA in the human brain
-
STECKELBROECK, S., M. WATZKA, B. STOFFEL-WAGNER, et al. 2001. Expression of 17β-hydroxysteroid dehydrogenase type 5 mRNA in the human brain. Mol. Cell. Endocrinol. 171: 165-168.
-
(2001)
Mol. Cell. Endocrinol.
, vol.171
, pp. 165-168
-
-
Steckelbroeck, S.1
Watzka, M.2
Stoffel-Wagner, B.3
-
59
-
-
0032587589
-
Characterization of 17β-hydroxysteroid dehydrogenase activity in brain tissue: Testosterone formation in the human temporal lobe
-
STECKELBROECK, S., B. STOFFEL-WAGNER, R. REICHELT, et al. 1999. Characterization of 17β-hydroxysteroid dehydrogenase activity in brain tissue: testosterone formation in the human temporal lobe. J. Neuroendocrinol. 11: 457-464.
-
(1999)
J. Neuroendocrinol.
, vol.11
, pp. 457-464
-
-
Steckelbroeck, S.1
Stoffel-Wagner, B.2
Reichelt, R.3
-
60
-
-
0027466693
-
A localization study of the cytochrome P-450(21)-linked monooxygenase system in adult rat brain
-
IWAHASHI, K., Y. KAWAI, H. SUWAKI, et al. 1993. A localization study of the cytochrome P-450(21)-linked monooxygenase system in adult rat brain. J. Steroid Biochem. Mol. Biol. 44: 163-169.
-
(1993)
J. Steroid Biochem. Mol. Biol.
, vol.44
, pp. 163-169
-
-
Iwahashi, K.1
Kawai, Y.2
Suwaki, H.3
-
61
-
-
0028818993
-
Messenger mRNAs encoding steroidogenic enzymes are expressed in rodent brain
-
STROMSTEDT, M. & M.R. WATERMAN. 1995. Messenger mRNAs encoding steroidogenic enzymes are expressed in rodent brain. Brain Res. Mol. Brain Res. 34: 75-88.
-
(1995)
Brain Res. Mol. Brain Res.
, vol.34
, pp. 75-88
-
-
Stromstedt, M.1
Waterman, M.R.2
-
62
-
-
0024460383
-
Extraadrenal steroid 21-hydroxylation is not mediated by P450c21
-
MELLON, S.H. & W.L. MILLER. 1989. Extraadrenal steroid 21-hydroxylation is not mediated by P450c21. J. Clin. Invest. 84: 1497-1502.
-
(1989)
J. Clin. Invest.
, vol.84
, pp. 1497-1502
-
-
Mellon, S.H.1
Miller, W.L.2
-
63
-
-
0035800619
-
Messenger RNA of steroid 21-hydroxylase (CYP21) is expressed in the human hippocampus
-
BEYENBURG, S., M. WATZKA, H. CLUSMANN, et al. 2001. Messenger RNA of steroid 21-hydroxylase (CYP21) is expressed in the human hippocampus. Neurosci. Lett. 308: 111-114.
-
(2001)
Neurosci. Lett.
, vol.308
, pp. 111-114
-
-
Beyenburg, S.1
Watzka, M.2
Clusmann, H.3
-
64
-
-
0028217179
-
Localization of 3beta-hydroxysteroid dehydrogenase in rat brain as studied by in situ hybridization
-
DUPONT, E., J. SIMARD, V. LUU-THE, et al. 1994. Localization of 3beta-hydroxysteroid dehydrogenase in rat brain as studied by in situ hybridization. Mol. Cell. Neurosci. 5: 119-123.
-
(1994)
Mol. Cell. Neurosci.
, vol.5
, pp. 119-123
-
-
Dupont, E.1
Simard, J.2
Luu-The, V.3
-
65
-
-
0028989525
-
A key enzyme in the biosynthesis of neurosteroids, 3β- hydroxysteroid dehydrogenase/D5-D4-isomerase (3β-HSD), is expressed in rat brain
-
GUENNOUN, R., R.J. FIDDES, M. GOUÉZOU, et al. 1995. A key enzyme in the biosynthesis of neurosteroids, 3β-hydroxysteroid dehydrogenase/D5-D4-isomerase (3β-HSD), is expressed in rat brain. Mol. Brain Res. 30: 287-300.
-
(1995)
Mol. Brain Res.
, vol.30
, pp. 287-300
-
-
Guennoun, R.1
Fiddes, R.J.2
Gouézou, M.3
-
66
-
-
12644291965
-
Corticoid synthesis in the central nervous system
-
GOMEZ-SANCHEZ, C.E., M.Y. ZHOU, E.N. COZZA, et al. 1996. Corticoid synthesis in the central nervous system. Endocr. Res. 22: 463-470.
-
(1996)
Endocr. Res.
, vol.22
, pp. 463-470
-
-
Gomez-Sanchez, C.E.1
Zhou, M.Y.2
Cozza, E.N.3
-
67
-
-
0030576843
-
Expression of cytochrome P45011B1 mRNA in the brain of normal and hypertensive transgenic rats
-
ERDMANN, B., H. GERST, A. LIPPOLDT, et al. 1996. Expression of cytochrome P45011B1 mRNA in the brain of normal and hypertensive transgenic rats. Brain Res. 733: 73-82.
-
(1996)
Brain Res.
, vol.733
, pp. 73-82
-
-
Erdmann, B.1
Gerst, H.2
Lippoldt, A.3
-
70
-
-
0028810283
-
Steroidogenic enzyme P450c17 is expressed in the embryonic central nervous system
-
COMPAGNONE, N.A., A. BUFONE & J.L.R. RUBENSTEIN. 1995. Steroidogenic enzyme P450c17 is expressed in the embryonic central nervous system. Endocrinology 136: 5212-5223.
-
(1995)
Endocrinology
, vol.136
, pp. 5212-5223
-
-
Compagnone, N.A.1
Bufone, A.2
Rubenstein, J.L.R.3
-
71
-
-
0026579057
-
Neuroactive steroids
-
PAUL, S.M. & R.H. PURDY. 1992. Neuroactive steroids. FASEB J. 6: 2311-2322.
-
(1992)
FASEB J.
, vol.6
, pp. 2311-2322
-
-
Paul, S.M.1
Purdy, R.H.2
-
72
-
-
0030630595
-
Neurosteroids: Of the nervous system, by the nervous system, for the nervous system
-
BAULIEU, E.E. 1997. Neurosteroids: of the nervous system, by the nervous system, for the nervous system. Rec. Prog. Horm. Res. 52: 1-33.
-
(1997)
Rec. Prog. Horm. Res.
, vol.52
, pp. 1-33
-
-
Baulieu, E.E.1
-
73
-
-
0032448780
-
Neurosteroids: A novel function of the brain
-
BAULIEU, E.E. 1998. Neurosteroids: a novel function of the brain. Psychoneuroendocrinology 23: 963-987.
-
(1998)
Psychoneuroendocrinology
, vol.23
, pp. 963-987
-
-
Baulieu, E.E.1
-
74
-
-
0032956181
-
Neurosteroids: Expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system
-
MENSAH-NYAGAN, A., J.L. DO-REGO, D. BEAUJEAN, et al. 1999. Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system. Pharmacol. Rev. 51: 63-81.
-
(1999)
Pharmacol. Rev.
, vol.51
, pp. 63-81
-
-
Mensah-Nyagan, A.1
Do-Rego, J.L.2
Beaujean, D.3
-
75
-
-
0033198566
-
Neuroactive steroids: Mechanism of action and neuropsychopharmacological perspectives
-
RUPPRECHT, R. & F. HOLSBOER. 1999. Neuroactive steroids: mechanism of action and neuropsychopharmacological perspectives. Trends Neurosci. 22: 410-416.
-
(1999)
Trends Neurosci.
, vol.22
, pp. 410-416
-
-
Rupprecht, R.1
Holsboer, F.2
-
76
-
-
0025995802
-
Pregnenolone sulfate: A positive allosteric modulator at the N-methyl-D-aspartate receptor
-
WU, F.S., T.T. GIBBS & D.H. FARB. 1991. Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor. Mol. Pharmacol. 40: 333-336.
-
(1991)
Mol. Pharmacol.
, vol.40
, pp. 333-336
-
-
Wu, F.S.1
Gibbs, T.T.2
Farb, D.H.3
-
77
-
-
0026578047
-
Steroid modulation of the strychnine-sensitive glycine receptor
-
PRINCE, R.J. & M.A. SIMMONDS. 1992. Steroid modulation of the strychnine-sensitive glycine receptor. Neuropharmacology. 31: 201-205.
-
(1992)
Neuropharmacology
, vol.31
, pp. 201-205
-
-
Prince, R.J.1
Simmonds, M.A.2
-
78
-
-
0029007089
-
3H] norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus
-
3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus. Proc. Natl. Acad. Sci. USA 92: 3774-3778.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3774-3778
-
-
Monnet, P.P.1
Mahé, V.2
Robel, P.3
-
80
-
-
0344364894
-
The anesthetic effect of steroid hormones
-
SELYE, H. 1941. The anesthetic effect of steroid hormones. Proc. Soc. Exp. Biol. Med. 46: 116-121.
-
(1941)
Proc. Soc. Exp. Biol. Med.
, vol.46
, pp. 116-121
-
-
Selye, H.1
-
81
-
-
0016759350
-
Implications for theories of anaesthesia of antagonism between anaesthetic and non-anaesthetic steroids
-
RICHARDS, C.D. & T.R. HESKETH. 1975. Implications for theories of anaesthesia of antagonism between anaesthetic and non-anaesthetic steroids. Nature 256: 179-182.
-
(1975)
Nature
, vol.256
, pp. 179-182
-
-
Richards, C.D.1
Hesketh, T.R.2
-
82
-
-
0017094587
-
Epileptic seizures in women related to plasma estrogen and progesterone during the menstrual cycle
-
BÄCKSTRÖM, T. 1976. Epileptic seizures in women related to plasma estrogen and progesterone during the menstrual cycle. Acta Neurol. Scand. 54: 321-347.
-
(1976)
Acta Neurol. Scand.
, vol.54
, pp. 321-347
-
-
Bäckström, T.1
-
83
-
-
0017260617
-
Epilepsy in women: Oestrogen and progesterone plasma levels
-
BÄCKSTRÖM, T. 1975. Epilepsy in women: oestrogen and progesterone plasma levels. Experientia 32: 248-249.
-
(1975)
Experientia
, vol.32
, pp. 248-249
-
-
Bäckström, T.1
-
84
-
-
0028149787
-
Anticonvulsant activity of neurosteroids: Correlation with γ-aminobutyric acid-evoked chloride current potentiation
-
KOKATE, T.G., B.E. SVENSSON & M.A. ROGAWSKI. 1994. Anticonvulsant activity of neurosteroids: Correlation with γ-aminobutyric acid-evoked chloride current potentiation. J. Pharmacol. Exp. Therap. 270: 1223-1229.
-
(1994)
J. Pharmacol. Exp. Therap.
, vol.270
, pp. 1223-1229
-
-
Kokate, T.G.1
Svensson, B.E.2
Rogawski, M.A.3
-
85
-
-
0025161662
-
Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex
-
BELELLI, D., N.C. LAN & K.W. GEE. 1990. Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex. Neurosci. Biobehav. Rev. 14: 315-322.
-
(1990)
Neurosci. Biobehav. Rev.
, vol.14
, pp. 315-322
-
-
Belelli, D.1
Lan, N.C.2
Gee, K.W.3
-
86
-
-
0030869099
-
Initial human experience with ganaxolone, a neuroactive steroid with antiepileptic activity
-
MONAGHAN, E.P., L.A. NAVALTA, L. SHUM, et al. 1997. Initial human experience with ganaxolone, a neuroactive steroid with antiepileptic activity. Epilepsia 38: 1026-1031.
-
(1997)
Epilepsia
, vol.38
, pp. 1026-1031
-
-
Monaghan, E.P.1
Navalta, L.A.2
Shum, L.3
-
87
-
-
0000168820
-
Ganaxolone in the treatment of complex partial seizures: A double-blind presurgical design
-
MONAGHAN, E.P., S. HARRIS, D. BLUM, et al. 1997. Ganaxolone in the treatment of complex partial seizures: a double-blind presurgical design. Epilepsia (Suppl. 8) 38: S179.
-
(1997)
Epilepsia
, vol.38
, Issue.8 SUPPL.
-
-
Monaghan, E.P.1
Harris, S.2
Blum, D.3
-
88
-
-
0006936954
-
Ganaxolone in the treatment of refractory infantile spasms
-
SHIELDS, W.D., J.F. KERRIGAN, D.L. BLUESTONE, et al. 1997. Ganaxolone in the treatment of refractory infantile spasms. Ann. Neurol. 42: 503-504.
-
(1997)
Ann. Neurol.
, vol.42
, pp. 503-504
-
-
Shields, W.D.1
Kerrigan, J.F.2
Bluestone, D.L.3
-
89
-
-
17044444204
-
Concentrations of 3alpha-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery
-
STRÖHLE, A., E. ROMEO, B. HERMANN, et al. 1999. Concentrations of 3alpha-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery. Biol. Psychol. 45: 274-277.
-
(1999)
Biol. Psychol.
, vol.45
, pp. 274-277
-
-
Ströhle, A.1
Romeo, E.2
Hermann, B.3
-
91
-
-
0030821426
-
The neuropsychopharmacological potential of neuroactive steroids
-
RUPPRECHT, R. 1997. The neuropsychopharmacological potential of neuroactive steroids. J. Psych. Res. 31: 297-314.
-
(1997)
J. Psych. Res.
, vol.31
, pp. 297-314
-
-
Rupprecht, R.1
-
92
-
-
0029961691
-
Relationship between symptom severity and steroid variation in women with premenstrual syndrome: Study on serum pregnenolone, pregnenolone sulfate, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one
-
WANG, M., L. SEIPPEL, R.H. PURDY, et al. 1996. Relationship between symptom severity and steroid variation in women with premenstrual syndrome: study on serum pregnenolone, pregnenolone sulfate, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one. J. Clin. Endocrinol. Metab.. 81: 1076-1082.
-
(1996)
J. Clin. Endocrinol. Metab..
, vol.81
, pp. 1076-1082
-
-
Wang, M.1
Seippel, L.2
Purdy, R.H.3
-
93
-
-
0026629845
-
Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men
-
ORENTREICH, N., J.L. BRIND, J.H. VOGELMAN, et al. 1992. Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men. J. Clin. Endocrinol. Metab. 75: 1002-1004.
-
(1992)
J. Clin. Endocrinol. Metab.
, vol.75
, pp. 1002-1004
-
-
Orentreich, N.1
Brind, J.L.2
Vogelman, J.H.3
-
94
-
-
0029995191
-
Adrenal secretion during major depression in 8- to 16-year olds. I. Altered diurnal rhythms in salivary cortisol and dehydroepiandrosterone (DHEA) at presentation
-
GOODYER, I.M., J. HERBERT, P.M. ALTHAM, et al. 1996. Adrenal secretion during major depression in 8-to 16-year olds. I. Altered diurnal rhythms in salivary cortisol and dehydroepiandrosterone (DHEA) at presentation. Psychol. Med. 26: 245-256.
-
(1996)
Psychol. Med.
, vol.26
, pp. 245-256
-
-
Goodyer, I.M.1
Herbert, J.2
Altham, P.M.3
-
95
-
-
0032539540
-
Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity
-
KIMONIDES, V.G., N.H. KHATIBI, C.N. SVENDSEN, et al. 1998 Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity. Proc. Natl. Acad. Sci. USA 95: 1852-1857.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 1852-1857
-
-
Kimonides, V.G.1
Khatibi, N.H.2
Svendsen, C.N.3
-
96
-
-
0026075969
-
Serum dehydroepiandrosterone sulfate in Alzheimer's disease and in multiinfarct dementia
-
NÄSMAN, B., B. OLSSON, T. BÄCKSTRÖM, et al. 1991. Serum dehydroepiandrosterone sulfate in Alzheimer's disease and in multiinfarct dementia. Biol. Psychiatry 30: 684-690.
-
(1991)
Biol. Psychiatry
, vol.30
, pp. 684-690
-
-
Näsman, B.1
Olsson, B.2
Bäckström, T.3
-
97
-
-
17544396291
-
Association between changes in adrenal secretion and cerebral morphometric correlates in normal aging and senile dementia
-
MAGRI, F., F. TERENZI, T. RICCIARDI, et al. 2000. Association between changes in adrenal secretion and cerebral morphometric correlates in normal aging and senile dementia. Dement. Geriatr. Cogn. Disord. 11: 90-99.
-
(2000)
Dement. Geriatr. Cogn. Disord.
, vol.11
, pp. 90-99
-
-
Magri, F.1
Terenzi, F.2
Ricciardi, T.3
-
98
-
-
0033969769
-
DHEA-S plasma levels and incidence of Alzheimer's disease
-
HILLEN, T., A. LUN, F.M. REISCHIES, et al. 2000. DHEA-S plasma levels and incidence of Alzheimer's disease. Biol. Psychiatry 47: 161-163.
-
(2000)
Biol. Psychiatry
, vol.47
, pp. 161-163
-
-
Hillen, T.1
Lun, A.2
Reischies, F.M.3
-
99
-
-
0030811021
-
Effects of a two-week physiological dehydroepiandrosterone substitution on cognitive performance and well-being in healthy elderly women and men
-
WOLF, O.T., O. NEUMANN, D.H. HELLHAMMER, et al. 1997. Effects of a two-week physiological dehydroepiandrosterone substitution on cognitive performance and well-being in healthy elderly women and men. J. Clin. Endocrinol. Metab. 82: 2363-2367.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 2363-2367
-
-
Wolf, O.T.1
Neumann, O.2
Hellhammer, D.H.3
-
100
-
-
0032406707
-
Effects of dehydroepiandrosterone replacement in elderly men on event-related potentials, memory and well-being
-
WOLF, O.T., E. NAUMANN, D.H. HELLHAMMER, et al. 1998. Effects of dehydroepiandrosterone replacement in elderly men on event-related potentials, memory and well-being. J. Gerontol. A Biol. Sci. Med. Sci. 53: M385-M390.
-
(1998)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.53
-
-
Wolf, O.T.1
Naumann, E.2
Hellhammer, D.H.3
|