메뉴 건너뛰기




Volumn 10, Issue 10, 2013, Pages 2598-2603

Neuroactive Steroid Levels are Modified in Cerebrospinal Fluid and Plasma of Post-Finasteride Patients Showing Persistent Sexual Side Effects and Anxious/Depressive Symptomatology

Author keywords

5 Reductase; Depression; Liquid Chromatography Tandem Mass Spectrometry; Progesterone; Testosterone

Indexed keywords

20ALPHA DIHYDROPROGESTERONE; 5ALPHA ANDROSTANE DERIVATIVE; ANDROSTANOLONE; ESTRADIOL; FINASTERIDE; SEPRANOLONE; STEROID; TESTOSTERONE; TETRAHYDROPROGESTERONE;

EID: 84885926631     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/jsm.12269     Document Type: Article
Times cited : (83)

References (23)
  • 2
    • 84871382108 scopus 로고    scopus 로고
    • 5α-reductases in human physiology: An unfolding story
    • Traish AM. 5α-reductases in human physiology: An unfolding story. Endocr Pract 2012;18:965-975.
    • (2012) Endocr Pract , vol.18 , pp. 965-975
    • Traish, A.M.1
  • 4
    • 42749086943 scopus 로고    scopus 로고
    • An alternate pathway for androgen regulation of brain function: Activation of estrogen receptor beta by the metabolite of dihydrotestosterone, 5α-androstane-3β,17β-diol
    • Handa RJ, Pak TR, Kudwa AE, Lund TD, Hinds L. An alternate pathway for androgen regulation of brain function: Activation of estrogen receptor beta by the metabolite of dihydrotestosterone, 5α-androstane-3β, 17β-diol. Horm Behav 2008;53:741-752.
    • (2008) Horm Behav , vol.53 , pp. 741-752
    • Handa, R.J.1    Pak, T.R.2    Kudwa, A.E.3    Lund, T.D.4    Hinds, L.5
  • 5
    • 33750830522 scopus 로고    scopus 로고
    • The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: Results of a randomized placebo-controlled study of dutasteride versus finasteride
    • Olsen EA, Hordinsky M, Whiting D, Stough D, Hobbs S, Ellis ML, Wilson T, Rittmaster RS. The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: Results of a randomized placebo-controlled study of dutasteride versus finasteride. J Am Acad Dermatol 2006;55:1014-1023.
    • (2006) J Am Acad Dermatol , vol.55 , pp. 1014-1023
    • Olsen, E.A.1    Hordinsky, M.2    Whiting, D.3    Stough, D.4    Hobbs, S.5    Ellis, M.L.6    Wilson, T.7    Rittmaster, R.S.8
  • 6
    • 0032947121 scopus 로고    scopus 로고
    • Finasteride: A review of its use in male pattern hair loss
    • McClellan KJ, Markham A. Finasteride: A review of its use in male pattern hair loss. Drugs 1999;57:111-126.
    • (1999) Drugs , vol.57 , pp. 111-126
    • McClellan, K.J.1    Markham, A.2
  • 8
    • 84868213002 scopus 로고    scopus 로고
    • Persistent sexual side effects of finasteride: Could they be permanent?
    • Irwig MS. Persistent sexual side effects of finasteride: Could they be permanent? J Sex Med 2012;9:2927-2932.
    • (2012) J Sex Med , vol.9 , pp. 2927-2932
    • Irwig, M.S.1
  • 9
    • 79957924605 scopus 로고    scopus 로고
    • Persistent sexual side effects of finasteride for male pattern hair loss
    • Irwig MS, Kolukula S. Persistent sexual side effects of finasteride for male pattern hair loss. J Sex Med 2011;8:1747-1753.
    • (2011) J Sex Med , vol.8 , pp. 1747-1753
    • Irwig, M.S.1    Kolukula, S.2
  • 10
    • 0036808650 scopus 로고    scopus 로고
    • Depression circumstantially related to the administration of finasteride for androgenetic alopecia
    • Altomare G, Capella GL. Depression circumstantially related to the administration of finasteride for androgenetic alopecia. J Dermatol 2002;29:665-669.
    • (2002) J Dermatol , vol.29 , pp. 665-669
    • Altomare, G.1    Capella, G.L.2
  • 12
    • 84866508901 scopus 로고    scopus 로고
    • Depressive symptoms and suicidal thoughts among former users of finasteride with persistent sexual side effects
    • Irwig MS. Depressive symptoms and suicidal thoughts among former users of finasteride with persistent sexual side effects. J Clin Psychiatry 2012;73:1220-1223.
    • (2012) J Clin Psychiatry , vol.73 , pp. 1220-1223
    • Irwig, M.S.1
  • 13
    • 84862213367 scopus 로고    scopus 로고
    • Progesterone synthesis in the nervous system: Implications for myelination and myelin repair
    • Schumacher M, Hussain R, Gago N, Oudinet JP, Mattern C, Ghoumari AM. Progesterone synthesis in the nervous system: Implications for myelination and myelin repair. Front Neurosci 2012;6:10. doi: 10.3389/fnins.2012.00010
    • (2012) Front Neurosci , vol.6 , pp. 10
    • Schumacher, M.1    Hussain, R.2    Gago, N.3    Oudinet, J.P.4    Mattern, C.5    Ghoumari, A.M.6
  • 15
    • 0025918687 scopus 로고
    • Anxiolytic effects of 3 α-hydroxy-5 α[β]-pregnan-20-one: Endogenous metabolites of progesterone that are active at the GABAA receptor
    • Bitran D, Hilvers RJ, Kellogg CK. Anxiolytic effects of 3 α-hydroxy-5 α[β]-pregnan-20-one: Endogenous metabolites of progesterone that are active at the GABAA receptor. Brain Res 1991;561:157-161.
    • (1991) Brain Res , vol.561 , pp. 157-161
    • Bitran, D.1    Hilvers, R.J.2    Kellogg, C.K.3
  • 18
    • 77958568334 scopus 로고    scopus 로고
    • Effects of short- and long-term gonadectomy on neuroactive steroid levels in the central and peripheral nervous system of male and female rats
    • Caruso D, Pesaresi M, Maschi O, Giatti S, Garcia-Segura LM, Melcangi RC. Effects of short- and long-term gonadectomy on neuroactive steroid levels in the central and peripheral nervous system of male and female rats. J Neuroendocrinol 2010;22:1137-1147.
    • (2010) J Neuroendocrinol , vol.22 , pp. 1137-1147
    • Caruso, D.1    Pesaresi, M.2    Maschi, O.3    Giatti, S.4    Garcia-Segura, L.M.5    Melcangi, R.C.6
  • 21
    • 0032539862 scopus 로고    scopus 로고
    • Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine
    • Uzunova V, Sheline Y, Davis JM, Rasmusson A, Uzunov DP, Costa E, Guidotti A. Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine. Proc Natl Acad Sci U S A 1998;95:3239-3244.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 3239-3244
    • Uzunova, V.1    Sheline, Y.2    Davis, J.M.3    Rasmusson, A.4    Uzunov, D.P.5    Costa, E.6    Guidotti, A.7
  • 22
    • 33744503400 scopus 로고    scopus 로고
    • Relevance of endogenous 3α-reduced neurosteroids to depression and antidepressant action
    • Uzunova V, Sampson L, Uzunov DP. Relevance of endogenous 3α-reduced neurosteroids to depression and antidepressant action. Psychopharmacology (Berl) 2006;186:351-361.
    • (2006) Psychopharmacology (Berl) , vol.186 , pp. 351-361
    • Uzunova, V.1    Sampson, L.2    Uzunov, D.P.3
  • 23
    • 79951991163 scopus 로고    scopus 로고
    • Adverse side effects of 5α-reductase inhibitors therapy: Persistent diminished libido and erectile dysfunction and depression in a subset of patients
    • Traish AM, Hassani J, Guay AT, Zitzmann M, Hansen ML. Adverse side effects of 5α-reductase inhibitors therapy: Persistent diminished libido and erectile dysfunction and depression in a subset of patients. J Sex Med 2011;8:872-884.
    • (2011) J Sex Med , vol.8 , pp. 872-884
    • Traish, A.M.1    Hassani, J.2    Guay, A.T.3    Zitzmann, M.4    Hansen, M.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.