메뉴 건너뛰기




Volumn 16, Issue , 2014, Pages

Influenza reverse genetics: Dissecting immunity and pathogenesis

Author keywords

[No Author keywords available]

Indexed keywords

CANCER VACCINE; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; INFLUENZA VACCINE; INFLUEZA VIRUS VECTOR; LIVE VACCINE; NONSTRUCTURAL PROTEIN 1; PROTEIN PB1; PROTEIN PB1 F2; PROTEIN PB2; UNCLASSIFIED DRUG; VIRUS HEMAGGLUTININ; VIRUS PROTEIN; VIRUS VECTOR; ANTIVIRUS AGENT;

EID: 84915760598     PISSN: 14623994     EISSN: None     Source Type: Journal    
DOI: 10.1017/erm.2014.4     Document Type: Review
Times cited : (9)

References (167)
  • 1
    • 84896448632 scopus 로고    scopus 로고
    • WHO(2009) Influenza Seasonal Fact Sheet, No. 211. WHO Media Centre
    • WHO(2009) Influenza Seasonal Fact Sheet, No. 211. WHO Media Centre
  • 2
    • 84861033023 scopus 로고    scopus 로고
    • Annual economic impacts of seasonal influenza on US counties: Spatial heterogeneity and patterns
    • Mao, L., Yang, Y. and Qiu, Y. (2012) Annual economic impacts of seasonal influenza on US counties: spatial heterogeneity and patterns. International Journal of Health Geographics 11, 16
    • (2012) International Journal of Health Geographics , vol.11 , pp. 16
    • Mao, L.1    Yang, Y.2    Qiu, Y.3
  • 3
    • 0026576063 scopus 로고
    • Evolution and ecology of influenza A viruses
    • Webster, R.G. et al. (1992) Evolution and ecology of influenza A viruses. Microbiological Review 56, 152-179
    • (1992) Microbiological Review , vol.56 , pp. 152-179
    • Webster, R.G.1
  • 4
    • 84863754680 scopus 로고    scopus 로고
    • An overlapping proteincoding region in influenza A virus segment 3 modulates the host response
    • Jagger, B.W. et al. (2012) An overlapping proteincoding region in influenza A virus segment 3 modulates the host response. Science 337, 199-204
    • (2012) Science , vol.337 , pp. 199-204
    • Jagger, B.W.1
  • 5
    • 33846982946 scopus 로고    scopus 로고
    • Structural characterization and oligomerization of PB1-F2, a proapoptotic influenza A virus protein
    • Bruns, K. et al. (2007) Structural characterization and oligomerization of PB1-F2, a proapoptotic influenza A virus protein. Journal of Biological Chemistry 282, 353-363
    • (2007) Journal of Biological Chemistry , vol.282 , pp. 353-363
    • Bruns, K.1
  • 6
    • 0036210827 scopus 로고    scopus 로고
    • The influenza virus nucleoprotein: A multifunctional RNA-binding protein pivotal to virus replication
    • Portela, A. and Digard, P. (2002) The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication. Journal of General Virology 83(Pt 4), 723-734
    • (2002) Journal of General Virology , vol.83 , Issue.PART 4 , pp. 723-734
    • Portela, A.1    Digard, P.2
  • 7
    • 0026006258 scopus 로고
    • Nuclear transport of influenza virus ribonucleoproteins: The viral matrix protein (M1) promotes export and inhibits import
    • Martin, K. and Helenius, A. (1991) Nuclear transport of influenza virus ribonucleoproteins: the viral matrix protein (M1) promotes export and inhibits import. Cell 67, 117-130
    • (1991) Cell , vol.67 , pp. 117-130
    • Martin, K.1    Helenius, A.2
  • 8
    • 0036007087 scopus 로고    scopus 로고
    • Influenza a virus M2 ion channel activity is essential for efficient replication in tissue culture
    • Takeda, M. et al. (2002) Influenza a virus M2 ion channel activity is essential for efficient replication in tissue culture. Journal of Virology 76, 1391-1399
    • (2002) Journal of Virology , vol.76 , pp. 1391-1399
    • Takeda, M.1
  • 9
    • 0345004816 scopus 로고    scopus 로고
    • Influenza A virus lacking the NS1 gene replicates in interferondeficient systems
    • Garcia-Sastre, A. et al. (1998) Influenza A virus lacking the NS1 gene replicates in interferondeficient systems. Virology 252, 324-330
    • (1998) Virology , vol.252 , pp. 324-330
    • Garcia-Sastre, A.1
  • 10
    • 0036842046 scopus 로고    scopus 로고
    • A decade after the generation of a negative-sense RNA virus from cloned cDNA - What have we learned?
    • Neumann, G., Whitt, M.A. and Kawaoka, Y. (2002) A decade after the generation of a negative-sense RNA virus from cloned cDNA - what have we learned? Journal of General Virology 83(Pt 11), 2635-2662
    • (2002) Journal of General Virology , vol.83 , Issue.PART 11 , pp. 2635-2662
    • Neumann, G.1    Whitt, M.A.2    Kawaoka, Y.3
  • 11
    • 11144356405 scopus 로고    scopus 로고
    • Responsiveness to a pandemic alert: Use of reverse genetics for rapid development of influenza vaccines
    • Webby, R.J. et al. (2004) Responsiveness to a pandemic alert: use of reverse genetics for rapid development of influenza vaccines. Lancet 363, 1099-1103
    • (2004) Lancet , vol.363 , pp. 1099-1103
    • Webby, R.J.1
  • 12
    • 0027292880 scopus 로고
    • Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cellmediated protective immunity against malaria
    • Li, S. et al. (1993) Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cellmediated protective immunity against malaria. Proceedings of the National Academy of Sciences USA 90, 5214-5218
    • (1993) Proceedings of the National Academy of Sciences USA , vol.90 , pp. 5214-5218
    • Li, S.1
  • 13
    • 67650917877 scopus 로고    scopus 로고
    • Evaluation of recombinant influenza virus-simian immunodeficiency virus vaccines in macaques
    • Sexton, A. et al. (2009) Evaluation of recombinant influenza virus-simian immunodeficiency virus vaccines in macaques. Journal of Virology 83, 7619-7628
    • (2009) Journal of Virology , vol.83 , pp. 7619-7628
    • Sexton, A.1
  • 14
    • 0017902199 scopus 로고
    • QB DNA-containing hybrid plasmids giving rise to QB phage formation in the bacterial host
    • Taniguchi, T., Palmieri, M. and Weissmann, C. (1978) QB DNA-containing hybrid plasmids giving rise to QB phage formation in the bacterial host. Nature 274, 223-228
    • (1978) Nature , vol.274 , pp. 223-228
    • Taniguchi, T.1    Palmieri, M.2    Weissmann, C.3
  • 15
    • 0029909104 scopus 로고    scopus 로고
    • Negative-strandRNAviruses: Genetic engineering and applications
    • Palese, P. et al. (1996) Negative-strandRNAviruses: genetic engineering and applications. Proceedings of the National Academy of Sciences USA 93, 11354-11358
    • (1996) Proceedings of the National Academy of Sciences USA , vol.93 , pp. 11354-11358
    • Palese, P.1
  • 16
    • 0024462510 scopus 로고
    • Promoter analysis of influenza virus RNA polymerase
    • Parvin, J.D. et al. (1989) Promoter analysis of influenza virus RNA polymerase. Journal of Virology 63, 5142-5152
    • (1989) Journal of Virology , vol.63 , pp. 5142-5152
    • Parvin, J.D.1
  • 17
    • 0024846089 scopus 로고
    • Amplification, expression, and packaging of foreign gene by influenza virus
    • Luytjes, W. et al. (1989) Amplification, expression, and packaging of foreign gene by influenza virus. Cell 59, 1107-1113
    • (1989) Cell , vol.59 , pp. 1107-1113
    • Luytjes, W.1
  • 19
    • 0030467993 scopus 로고    scopus 로고
    • Rescue of a segmented negative-strand RNAvirus entirely from cloned complementary DNAs
    • Bridgen, A. and Elliott, R.M. (1996) Rescue of a segmented negative-strand RNAvirus entirely from cloned complementary DNAs. Proceedings of the National Academy of Sciences USA 93, 15400-15404
    • (1996) Proceedings of the National Academy of Sciences USA , vol.93 , pp. 15400-15404
    • Bridgen, A.1    Elliott, R.M.2
  • 20
    • 13044287344 scopus 로고    scopus 로고
    • Generation of influenzaA viruses entirely from cloned cDNAs
    • Neumann, G. et al. (1999) Generation of influenzaA viruses entirely from cloned cDNAs. Proceedings of the National Academy of Sciences USA 96, 9345-9350
    • (1999) Proceedings of the National Academy of Sciences USA , vol.96 , pp. 9345-9350
    • Neumann, G.1
  • 21
    • 0027234199 scopus 로고
    • RNA polymerase i catalysed transcription of insert viral cDNA
    • Zobel, A., Neumann, G. and Hobom, G. (1993) RNA polymerase I catalysed transcription of insert viral cDNA. Nucleic Acids Research 21, 3607-3614
    • (1993) Nucleic Acids Research , vol.21 , pp. 3607-3614
    • Zobel, A.1    Neumann, G.2    Hobom, G.3
  • 22
    • 0034705225 scopus 로고    scopus 로고
    • A DNA transfection system for generation of influenza A virus from eight plasmids
    • Hoffmann, E. et al. (2000) A DNA transfection system for generation of influenza A virus from eight plasmids. Proceedings of the National Academy of Sciences USA 97, 6108-6113
    • (2000) Proceedings of the National Academy of Sciences USA , vol.97 , pp. 6108-6113
    • Hoffmann, E.1
  • 23
    • 28044438708 scopus 로고    scopus 로고
    • An improved reverse genetics system for influenza A virus generation and its implications for vaccine production
    • Neumann, G. et al. (2005) An improved reverse genetics system for influenza A virus generation and its implications for vaccine production. Proceedings of the National Academy of Sciences USA 102, 16825-16829
    • (2005) Proceedings of the National Academy of Sciences USA , vol.102 , pp. 16825-16829
    • Neumann, G.1
  • 24
    • 69449100838 scopus 로고    scopus 로고
    • A one-plasmid system to generate influenza virus in cultured chicken cells for potential use in influenza vaccine
    • Zhang, X. et al. (2009) A one-plasmid system to generate influenza virus in cultured chicken cells for potential use in influenza vaccine. Journal of Virology 83, 9296-9303
    • (2009) Journal of Virology , vol.83 , pp. 9296-9303
    • Zhang, X.1
  • 25
    • 0033783032 scopus 로고    scopus 로고
    • Receptor binding and membrane fusion in virus entry: The influenza hemagglutinin
    • Skehel, J.J. and Wiley, D.C. (2000) Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. Annual Reviewin Biochemistry 69, 531-569
    • (2000) Annual Reviewin Biochemistry , vol.69 , pp. 531-569
    • Skehel, J.J.1    Wiley, D.C.2
  • 26
    • 0027988832 scopus 로고
    • Receptor specificity in human, avian, and equine H2 and H3 influenza virus isolates
    • Connor, R.J. et al. (1994) Receptor specificity in human, avian, and equine H2 and H3 influenza virus isolates. Virology 205, 17-23
    • (1994) Virology , vol.205 , pp. 17-23
    • Connor, R.J.1
  • 27
    • 34248214025 scopus 로고    scopus 로고
    • Effective replication of human influenza viruses in mice lacking a major alpha2,6 sialyltransferase
    • Glaser, L. et al. (2007) Effective replication of human influenza viruses in mice lacking a major alpha2,6 sialyltransferase. Virus Research 126, 9-18
    • (2007) Virus Research , vol.126 , pp. 9-18
    • Glaser, L.1
  • 28
    • 79959541956 scopus 로고    scopus 로고
    • Avian influenza viruses infect primary human bronchial epithelial cells unconstrained by sialic acid alpha2,3 residues
    • doi:10.1371/journal.pone.0021183
    • Oshansky, C.M. et al. (2011)Avian influenza viruses infect primary human bronchial epithelial cells unconstrained by sialic acid alpha2,3 residues. PLoS One 6, e21183. doi:10.1371/journal.pone.0021183
    • (2011) PLoS One , vol.6
    • Oshansky, C.M.1
  • 29
    • 0025246369 scopus 로고
    • Structural basis of immune recognition of influenza virus hemagglutinin
    • Wilson, I.A. and Cox, N.J. (1990) Structural basis of immune recognition of influenza virus hemagglutinin. Annual Review of Immunology 8, 737-771
    • (1990) Annual Review of Immunology , vol.8 , pp. 737-771
    • Wilson, I.A.1    Cox, N.J.2
  • 32
    • 0033574005 scopus 로고    scopus 로고
    • Origin and evolution of the 1918 "Spanish" influenza virus hemagglutinin gene
    • Reid, A.H. et al. (1999) Origin and evolution of the 1918 "Spanish" influenza virus hemagglutinin gene. Proceedings of the National Academy of Sciences USA 96, 1651-1656
    • (1999) Proceedings of the National Academy of Sciences USA , vol.96 , pp. 1651-1656
    • Reid, A.H.1
  • 33
    • 0033856695 scopus 로고    scopus 로고
    • Early alterations of the receptor-binding properties of H1, H2, and H3 avian influenza virus hemagglutinins after their introduction into mammals
    • Matrosovich, M. et al. (2000) Early alterations of the receptor-binding properties of H1, H2, and H3 avian influenza virus hemagglutinins after their introduction into mammals. Journal of Virology 74, 8502-8512
    • (2000) Journal of Virology , vol.74 , pp. 8502-8512
    • Matrosovich, M.1
  • 35
    • 84896463243 scopus 로고    scopus 로고
    • Influenza and influenza vaccines - The need for further developments
    • Fleming, D.M. (2010) Influenza and influenza vaccines - the need for further developments. European Infectious Disease 4(Suppl. 1), 2-6
    • (2010) European Infectious Disease , vol.4 , Issue.SUPPL. 1 , pp. 2-6
    • Fleming, D.M.1
  • 36
    • 0442323299 scopus 로고    scopus 로고
    • Influenza virus: Immunity and vaccination strategies Comparison of the immune response to inactivated and live, attenuated influenza vaccines
    • Cox, R.J., Brokstad, K.A. and Ogra, P. (2004) Influenza virus: immunity and vaccination strategies. Comparison of the immune response to inactivated and live, attenuated influenza vaccines. Scandinavian Journal of Immunology 59, 1-15
    • (2004) Scandinavian Journal of Immunology , vol.59 , pp. 1-15
    • Cox, R.J.1    Brokstad, K.A.2    Ogra, P.3
  • 37
    • 0027973478 scopus 로고
    • The efficacy of influenza vaccination in elderly individuals A randomized double-blind placebo-controlled trial
    • Govaert, T.M. et al. (1994) The efficacy of influenza vaccination in elderly individuals. A randomized double-blind placebo-controlled trial. Journal of American Medical Association 272, 1661-1665
    • (1994) Journal of American Medical Association , vol.272 , pp. 1661-1665
    • Govaert, T.M.1
  • 38
    • 0032885520 scopus 로고    scopus 로고
    • Is there a role for a mucosal influenza vaccine in the elderly?
    • Corrigan, E.M. and Clancy, R.L. (1999) Is there a role for a mucosal influenza vaccine in the elderly? Drugs Aging 15, 169-181
    • (1999) Drugs Aging , vol.15 , pp. 169-181
    • Corrigan, E.M.1    Clancy, R.L.2
  • 41
    • 80052015820 scopus 로고    scopus 로고
    • Live attenuated influenza vaccine (FluMist(R); Fluenz): A review of its use in the prevention of seasonal influenza in children and adults
    • Carter, N.J. and Curran, M.P. (2011) Live attenuated influenza vaccine (FluMist(R); Fluenz): a review of its use in the prevention of seasonal influenza in children and adults. Drugs 71, 1591-1622
    • (2011) Drugs , vol.71 , pp. 1591-1622
    • Carter, N.J.1    Curran, M.P.2
  • 42
  • 43
    • 77649274431 scopus 로고    scopus 로고
    • Research and development of universal influenza vaccines
    • Du, L., Zhou, Y. and Jiang, S. (2010) Research and development of universal influenza vaccines. Microbes and Infection 12, 280-286
    • (2010) Microbes and Infection , vol.12 , pp. 280-286
    • Du, L.1    Zhou, Y.2    Jiang, S.3
  • 44
    • 55849125109 scopus 로고    scopus 로고
    • Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals
    • Lee, L.Y. et al. (2008) Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals. Journal of Clinical Investigation 118, 3478-3490
    • (2008) Journal of Clinical Investigation , vol.118 , pp. 3478-3490
    • Lee, L.Y.1
  • 45
    • 31344453965 scopus 로고    scopus 로고
    • Cell-mediated protection in influenza infection
    • Thomas, P.G. et al. (2006) Cell-mediated protection in influenza infection. Emerging Infectious Diseases 12, 48-54
    • (2006) Emerging Infectious Diseases , vol.12 , pp. 48-54
    • Thomas, P.G.1
  • 46
    • 80053585941 scopus 로고    scopus 로고
    • A human multiepitope recombinant vaccinia virus as a universal Tcellvaccine candidateagainst influenzavirus
    • doi:10.1371/journal.pone.0025938
    • Goodman, A.G. et al. (2011) A human multiepitope recombinant vaccinia virus as a universal Tcellvaccine candidateagainst influenzavirus.PLoS One 6, e25938. doi:10.1371/journal.pone.0025938
    • (2011) PLoS One , vol.6
    • Goodman, A.G.1
  • 47
    • 34447568705 scopus 로고    scopus 로고
    • Pandemic vaccines: Promises and pitfalls
    • Booy, R. et al. (2006) Pandemic vaccines: promises and pitfalls. Medical Journal of Australia 185(10 Suppl), S62-S65
    • (2006) Medical Journal of Australia , vol.185 , Issue.10 SUPPL.
    • Booy, R.1
  • 48
    • 0037227584 scopus 로고    scopus 로고
    • Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics
    • Subbarao, K. et al. (2003) Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics. Virology 305, 192-200
    • (2003) Virology , vol.305 , pp. 192-200
    • Subbarao, K.1
  • 49
    • 0035823083 scopus 로고    scopus 로고
    • Molecular basis for high virulence of Hong Kong H5N1 influenza Aviruses
    • Hatta, M. et al. (2001) Molecular basis for high virulence of Hong Kong H5N1 influenza Aviruses. Science 293, 1840-1842
    • (2001) Science , vol.293 , pp. 1840-1842
    • Hatta, M.1
  • 50
    • 58849167264 scopus 로고    scopus 로고
    • Viral RNA polymerase complex promotes optimal growth of 1918 virus in the lower respiratory tract of ferrets
    • Watanabe, T. et al. (2009) Viral RNA polymerase complex promotes optimal growth of 1918 virus in the lower respiratory tract of ferrets. Proceedings of the National Academy of Sciences USA 106, 588-592
    • (2009) Proceedings of the National Academy of Sciences USA , vol.106 , pp. 588-592
    • Watanabe, T.1
  • 51
    • 26444506691 scopus 로고    scopus 로고
    • Characterization of the 1918 influenza virus polymerase genes
    • Taubenberger, J.K. et al. (2005) Characterization of the 1918 influenza virus polymerase genes. Nature 437, 889-893
    • (2005) Nature , vol.437 , pp. 889-893
    • Taubenberger, J.K.1
  • 52
    • 0027468737 scopus 로고
    • A single amino acid in the PB2 gene of influenza A virus is a determinant of host range
    • Subbarao, E.K., London, W. and Murphy, B.R. (1993) A single amino acid in the PB2 gene of influenza A virus is a determinant of host range. Journal of Virology 67, 1761-1764
    • (1993) Journal of Virology , vol.67 , pp. 1761-1764
    • Subbarao, E.K.1    London, W.2    Murphy, B.R.3
  • 53
    • 29444438899 scopus 로고    scopus 로고
    • The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host
    • Gabriel, G. et al. (2005) The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host. Proceedings of the National Academy of Sciences USA 102, 18590-18595
    • (2005) Proceedings of the National Academy of Sciences USA , vol.102 , pp. 18590-18595
    • Gabriel, G.1
  • 54
    • 1542287451 scopus 로고    scopus 로고
    • Characterization of a neuraminidase-deficient influenza a virus as a potential gene delivery vector and a live vaccine
    • Shinya, K. et al. (2004) Characterization of a neuraminidase-deficient influenza a virus as a potential gene delivery vector and a live vaccine. Journal of Virology 78, 3083-3088
    • (2004) Journal of Virology , vol.78 , pp. 3083-3088
    • Shinya, K.1
  • 55
    • 24644484686 scopus 로고    scopus 로고
    • Molecular basis of replication of duck H5N1 influenza viruses in a mammalian mouse model
    • Li, Z. et al. (2005) Molecular basis of replication of duck H5N1 influenza viruses in a mammalian mouse model. Journal of Virology 79, 12058-12064
    • (2005) Journal of Virology , vol.79 , pp. 12058-12064
    • Li, Z.1
  • 56
    • 33749511112 scopus 로고    scopus 로고
    • Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia
    • de Jong, M.D. et al. (2006) Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nature Medicine 12, 1203-1207
    • (2006) Nature Medicine , vol.12 , pp. 1203-1207
    • De Jong, M.D.1
  • 57
    • 0023201470 scopus 로고
    • The three influenza virus polymerase (P) proteins not associated with viral nucleocapsids in the infected cell are in the form of a complex
    • Detjen, B.M. et al. (1987) The three influenza virus polymerase (P) proteins not associated with viral nucleocapsids in the infected cell are in the form of a complex. Journal of Virology 61, 16-22
    • (1987) Journal of Virology , vol.61 , pp. 16-22
    • Detjen, B.M.1
  • 58
    • 42949124025 scopus 로고    scopus 로고
    • Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus
    • Pappas, C. et al. (2008) Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus. Proceedings of the National Academy of Sciences USA 105, 3064-3069
    • (2008) Proceedings of the National Academy of Sciences USA , vol.105 , pp. 3064-3069
    • Pappas, C.1
  • 59
    • 0035658084 scopus 로고    scopus 로고
    • A novel influenza A virus mitochondrial protein that induces cell death
    • Chen, W. et al. (2001) A novel influenza A virus mitochondrial protein that induces cell death. Nature Medicine 7, 1306-1312
    • (2001) Nature Medicine , vol.7 , pp. 1306-1312
    • Chen, W.1
  • 60
    • 42149098369 scopus 로고    scopus 로고
    • The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein
    • Mazur, I. et al. (2008) The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein. Cellular Microbiology 10, 1140-1152
    • (2008) Cellular Microbiology , vol.10 , pp. 1140-1152
    • Mazur, I.1
  • 61
    • 34848926238 scopus 로고    scopus 로고
    • Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia
    • McAuley, J.L. et al. (2007) Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia. Cell Host and Microbe 2, 240-249
    • (2007) Cell Host and Microbe , vol.2 , pp. 240-249
    • McAuley, J.L.1
  • 62
    • 36049034216 scopus 로고    scopus 로고
    • A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence
    • Conenello, G.M. et al. (2007) A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence. PLoS Pathogens 3, 1414-1421
    • (2007) PLoS Pathogens , vol.3 , pp. 1414-1421
    • Conenello, G.M.1
  • 63
    • 0028923921 scopus 로고
    • Influenza virus NS1 protein enhances the rate of translation initiation of viral mRNAs
    • de la Luna, S. et al. (1995) Influenza virus NS1 protein enhances the rate of translation initiation of viral mRNAs. Journal of Virology 69, 2427-2433
    • (1995) Journal of Virology , vol.69 , pp. 2427-2433
    • De La Luna, S.1
  • 64
    • 33947381763 scopus 로고    scopus 로고
    • Influenza A virus NS1 protein activates the PI3 K/Akt pathway to mediate antiapoptotic signaling responses
    • Ehrhardt, C. et al. (2007) Influenza A virus NS1 protein activates the PI3 K/Akt pathway to mediate antiapoptotic signaling responses. Journal of Virology 81, 3058-3067
    • (2007) Journal of Virology , vol.81 , pp. 3058-3067
    • Ehrhardt, C.1
  • 65
    • 0345167006 scopus 로고    scopus 로고
    • A recombinant influenza Avirus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice
    • Donelan, N.R., Basler, C.F. and Garcia-Sastre, A. (2003) A recombinant influenza Avirus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice. Journal of Virology 77, 13257-13266
    • (2003) Journal of Virology , vol.77 , pp. 13257-13266
    • Donelan, N.R.1    Basler, C.F.2    Garcia-Sastre, A.3
  • 66
    • 33847670199 scopus 로고    scopus 로고
    • NS1 protein of influenzaAvirus inhibits the function of intracytoplasmic pathogen sensor, RIG-I
    • Guo, Z. et al. (2007) NS1 protein of influenzaAvirus inhibits the function of intracytoplasmic pathogen sensor, RIG-I. American Journal of Respiratory Cell and Molecular Biology 36, 263-269
    • (2007) American Journal of Respiratory Cell and Molecular Biology , vol.36 , pp. 263-269
    • Guo, Z.1
  • 67
    • 33846061693 scopus 로고    scopus 로고
    • Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza Avirus
    • Mibayashi, M. et al. (2007) Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza Avirus. Journal of Virology 81, 514-524
    • (2007) Journal of Virology , vol.81 , pp. 514-524
    • Mibayashi, M.1
  • 68
    • 33947171000 scopus 로고    scopus 로고
    • IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein
    • Opitz, B. et al. (2007) IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein. Cellular Microbiology 9, 930-938
    • (2007) Cellular Microbiology , vol.9 , pp. 930-938
    • Opitz, B.1
  • 69
    • 33644835546 scopus 로고    scopus 로고
    • The virulence of the 1918 pandemic influenza virus: Unraveling the enigma
    • Taubenberger, J.K. (2005) The virulence of the 1918 pandemic influenza virus: unraveling the enigma. Archives of Virology, Supplement (19), 101-115
    • (2005) Archives of Virology, Supplement , Issue.19 , pp. 101-115
    • Taubenberger, J.K.1
  • 70
    • 0031925893 scopus 로고    scopus 로고
    • Transfectant influenza A viruses with long deletions in the NS1 protein grow efficiently in Vero cells
    • Egorov, A. et al. (1998) Transfectant influenza A viruses with long deletions in the NS1 protein grow efficiently in Vero cells. Journal of Virology 72, 6437-6441
    • (1998) Journal of Virology , vol.72 , pp. 6437-6441
    • Egorov, A.1
  • 71
    • 0037173048 scopus 로고    scopus 로고
    • Emergence of multiple genotypes ofH5N1avian influenza viruses inHong Kong SAR
    • Guan, Y. et al. (2002) Emergence of multiple genotypes ofH5N1avian influenza viruses inHong Kong SAR. Proceedings of the National Academy of Sciences USA 99, 8950-8955
    • (2002) Proceedings of the National Academy of Sciences USA , vol.99 , pp. 8950-8955
    • Guan, Y.1
  • 72
    • 0036734038 scopus 로고    scopus 로고
    • Lethal H5N1 influenza viruses escape host antiviral cytokine responses
    • Seo, S.H., Hoffmann, E. and Webster, R.G. (2002) Lethal H5N1 influenza viruses escape host antiviral cytokine responses. Nature Medicine 8, 950-954
    • (2002) Nature Medicine , vol.8 , pp. 950-954
    • Seo, S.H.1    Hoffmann, E.2    Webster, R.G.3
  • 73
    • 33645067624 scopus 로고    scopus 로고
    • Large-scale sequence analysis of avian influenza isolates
    • Obenauer, J.C. et al. (2006) Large-scale sequence analysis of avian influenza isolates. Science 311, 1576-1580
    • (2006) Science , vol.311 , pp. 1576-1580
    • Obenauer, J.C.1
  • 74
    • 0034916230 scopus 로고    scopus 로고
    • PDZ domains and the organization of supramolecular complexes
    • Sheng, M. and Sala, C. (2001) PDZ domains and the organization of supramolecular complexes. Annual Review in Neuroscience 24, 1-29
    • (2001) Annual Review in Neuroscience , vol.24 , pp. 1-29
    • Sheng, M.1    Sala, C.2
  • 75
    • 41949123710 scopus 로고    scopus 로고
    • A new influenza virus virulence determinant: The NS1 protein four Cterminal residues modulate pathogenicity
    • Jackson, D. et al. (2008) A new influenza virus virulence determinant: the NS1 protein four Cterminal residues modulate pathogenicity. Proceedings of the National Academy of Sciences USA 105, 4381-4386
    • (2008) Proceedings of the National Academy of Sciences USA , vol.105 , pp. 4381-4386
    • Jackson, D.1
  • 76
    • 0032995665 scopus 로고    scopus 로고
    • RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific basic amino acids
    • Wang, W. et al. (1999) RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific basic amino acids. RNA 5, 195-205
    • (1999) RNA , vol.5 , pp. 195-205
    • Wang, W.1
  • 77
    • 34247566514 scopus 로고    scopus 로고
    • A site on the influenza Avirus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis
    • Min, J.Y. et al. (2007) A site on the influenza Avirus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis. Virology 363, 236-243
    • (2007) Virology , vol.363 , pp. 236-243
    • Min, J.Y.1
  • 78
    • 54449099369 scopus 로고    scopus 로고
    • The multifunctional NS1 protein of influenza A viruses
    • Hale, B.G. et al. (2008) The multifunctional NS1 protein of influenza A viruses. Journal of General Virology 89(Pt 10), 2359-2376
    • (2008) Journal of General Virology , vol.89 , Issue.PART 10 , pp. 2359-2376
    • Hale, B.G.1
  • 79
    • 84869214374 scopus 로고    scopus 로고
    • Contribution of NS1 effector domain dimerization to Influenza A virus replication and virulence
    • Ayllon, J. et al. (2012) Contribution of NS1 effector domain dimerization to Influenza A virus replication and virulence. Journal of Virology 86, 13095-13098
    • (2012) Journal of Virology , vol.86 , pp. 13095-13098
    • Ayllon, J.1
  • 80
    • 33748950305 scopus 로고    scopus 로고
    • Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium
    • Bottcher, E. et al. (2006) Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium. Journal of Virology 80, 9896-9898
    • (2006) Journal of Virology , vol.80 , pp. 9896-9898
    • Bottcher, E.1
  • 81
    • 0028331821 scopus 로고
    • Reverse genetics provides direct evidence for a correlation of hemagglutinin cleavability and virulence of an avian influenza A virus
    • Horimoto, T. and Kawaoka, Y. (1994) Reverse genetics provides direct evidence for a correlation of hemagglutinin cleavability and virulence of an avian influenza A virus. Journal of Virology 68, 3120-3128
    • (1994) Journal of Virology , vol.68 , pp. 3120-3128
    • Horimoto, T.1    Kawaoka, Y.2
  • 82
    • 84860681358 scopus 로고    scopus 로고
    • Residue Y161 of influenza virus hemagglutinin is involved in viral recognition of sialylated complexes from different hosts
    • Wang, M. et al. (2012) Residue Y161 of influenza virus hemagglutinin is involved in viral recognition of sialylated complexes from different hosts. Journal of Virology 86, 4455-4462
    • (2012) Journal of Virology , vol.86 , pp. 4455-4462
    • Wang, M.1
  • 83
    • 23844487765 scopus 로고    scopus 로고
    • A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity
    • Glaser, L. et al. (2005) A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity. Journal of Virology 79, 11533-11536
    • (2005) Journal of Virology , vol.79 , pp. 11533-11536
    • Glaser, L.1
  • 84
    • 80053604087 scopus 로고    scopus 로고
    • A single amino acid in theHAof pH1N1 2009 influenza virus affects cell tropism in human airway epithelium, but not transmission in ferrets
    • doi:10.1371/journal.pone.0025755
    • van Doremalen, N. et al. (2011) A single amino acid in theHAof pH1N1 2009 influenza virus affects cell tropism in human airway epithelium, but not transmission in ferrets. PLoS One 6, e25755. doi:10.1371/journal.pone.0025755
    • (2011) PLoS One , vol.6
    • Van Doremalen, N.1
  • 85
    • 79953147888 scopus 로고    scopus 로고
    • Only two residues are responsible for the dramatic difference in receptor binding between swine and new pandemic H1 hemagglutinin
    • de Vries, R.P. et al. (2011) Only two residues are responsible for the dramatic difference in receptor binding between swine and new pandemic H1 hemagglutinin. Journal of Biological Chemistry 286, 5868-5875
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 5868-5875
    • De Vries, R.P.1
  • 86
    • 77954437879 scopus 로고    scopus 로고
    • Evasion of innate and adaptive immune responses by influenza A virus
    • Schmolke, M. and Garcia-Sastre, A. (2010) Evasion of innate and adaptive immune responses by influenza A virus. Cellular Microbiology 12, 873-880
    • (2010) Cellular Microbiology , vol.12 , pp. 873-880
    • Schmolke, M.1    Garcia-Sastre, A.2
  • 87
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi, O. and Akira, S. (2010) Pattern recognition receptors and inflammation. Cell 140, 805-820
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 88
    • 33947206046 scopus 로고    scopus 로고
    • Cutting Edge: Influenza A virus activates TLR3-dependent inflammatory and RIG-I-dependent antiviral responses in human lung epithelial cells
    • Le Goffic, R. et al. (2007) Cutting Edge: influenza A virus activates TLR3-dependent inflammatory and RIG-I-dependent antiviral responses in human lung epithelial cells. Journal of Immunology 178, 3368-3372
    • (2007) Journal of Immunology , vol.178 , pp. 3368-3372
    • Le Goffic, R.1
  • 89
    • 0033795196 scopus 로고    scopus 로고
    • Interferons: Cell signalling, immune modulation, antiviral response and virus countermeasures
    • Goodbourn, S., Didcock, L. and Randall, R.E. (2000) Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures. Journal of General Virology 81(Pt 10), 2341-2364
    • (2000) Journal of General Virology , vol.81 , Issue.PART 10 , pp. 2341-2364
    • Goodbourn, S.1    Didcock, L.2    Randall, R.E.3
  • 90
    • 0344642936 scopus 로고    scopus 로고
    • Type i interferon induction pathway, but not released interferon, participates in the maturation of dendritic cells induced by negative-strand RNAviruses
    • Lopez, C.B. et al. (2003) Type I interferon induction pathway, but not released interferon, participates in the maturation of dendritic cells induced by negative-strand RNAviruses. Journal of Infectious Diseases 187, 1126-1136
    • (2003) Journal of Infectious Diseases , vol.187 , pp. 1126-1136
    • Lopez, C.B.1
  • 91
    • 33745242372 scopus 로고    scopus 로고
    • Influenza virus evades innate and adaptive immunity via the NS1 protein
    • Fernandez-Sesma, A. et al. (2006) Influenza virus evades innate and adaptive immunity via the NS1 protein. Journal of Virology 80, 6295-6304
    • (2006) Journal of Virology , vol.80 , pp. 6295-6304
    • Fernandez-Sesma, A.1
  • 92
    • 67449097020 scopus 로고    scopus 로고
    • The NS1 protein of a human influenza virus inhibits type i interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells
    • Haye, K. et al. (2009) The NS1 protein of a human influenza virus inhibits type I interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells. Journal of Virology 83, 6849-6862
    • (2009) Journal of Virology , vol.83 , pp. 6849-6862
    • Haye, K.1
  • 93
    • 17344362313 scopus 로고    scopus 로고
    • Ligand recognition by alpha beta T cell receptors
    • Davis, M.M. et al. (1998) Ligand recognition by alpha beta T cell receptors. Annual Review of Immunology 16, 523-544
    • (1998) Annual Review of Immunology , vol.16 , pp. 523-544
    • Davis, M.M.1
  • 94
    • 0036168233 scopus 로고    scopus 로고
    • Sequence variation in a newly identified HLA-B35-restricted epitope in the influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes
    • Boon, A.C. et al. (2002) Sequence variation in a newly identified HLA-B35-restricted epitope in the influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes. Journal of Virology 76, 2567-2572
    • (2002) Journal of Virology , vol.76 , pp. 2567-2572
    • Boon, A.C.1
  • 95
    • 0035913225 scopus 로고    scopus 로고
    • Evolution and transmission of stable CTLescape mutations inHIV infection
    • Goulder, P.J. et al. (2001) Evolution and transmission of stable CTLescape mutations inHIV infection. Nature 412, 334-338
    • (2001) Nature , vol.412 , pp. 334-338
    • Goulder, P.J.1
  • 96
    • 16944366524 scopus 로고    scopus 로고
    • Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS
    • Goulder, P.J. et al. (1997) Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS. Nature Medicine 3, 212-217
    • (1997) Nature Medicine , vol.3 , pp. 212-217
    • Goulder, P.J.1
  • 97
    • 0033046472 scopus 로고    scopus 로고
    • Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses
    • Yewdell, J.W. and Bennink, J.R. (1999) Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses. Annual Review of Immunology 17, 51-88
    • (1999) Annual Review of Immunology , vol.17 , pp. 51-88
    • Yewdell, J.W.1    Bennink, J.R.2
  • 98
    • 0022483534 scopus 로고
    • The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides
    • Townsend, A.R. et al. (1986) The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell 44, 959-968
    • (1986) Cell , vol.44 , pp. 959-968
    • Townsend, A.R.1
  • 99
    • 0034027174 scopus 로고    scopus 로고
    • A previously unrecognized H-2D(b)-restricted peptide prominent in the primary influenza A virus-specific CD8(+) T-cell response is much less apparent following secondary challenge
    • Belz, G.T. et al. (2000) A previously unrecognized H-2D(b)-restricted peptide prominent in the primary influenza A virus-specific CD8(+) T-cell response is much less apparent following secondary challenge. Journal of Virology 74, 3486-3493
    • (2000) Journal of Virology , vol.74 , pp. 3486-3493
    • Belz, G.T.1
  • 100
    • 0030436878 scopus 로고    scopus 로고
    • Role of non-anchor residues of Db-restricted peptides in class i binding and TCR triggering
    • Sigal, L.J. and Wylie, D.E. (1996) Role of non-anchor residues of Db-restricted peptides in class I binding and TCR triggering. Molecular Immunology 33, 1323-1333
    • (1996) Molecular Immunology , vol.33 , pp. 1323-1333
    • Sigal, L.J.1    Wylie, D.E.2
  • 101
    • 0034608650 scopus 로고    scopus 로고
    • Viral escape by selection of cytotoxic T cell-resistant variants in influenza A virus pneumonia
    • Price, G.E. et al. (2000) Viral escape by selection of cytotoxic T cell-resistant variants in influenza A virus pneumonia. Journal of Experimental Medicine 191, 1853-1867
    • (2000) Journal of Experimental Medicine , vol.191 , pp. 1853-1867
    • Price, G.E.1
  • 102
    • 0038132939 scopus 로고    scopus 로고
    • Protection and compensation in the influenza virus-specific CD8+ T cell response
    • Webby, R.J. et al. (2003) Protection and compensation in the influenza virus-specific CD8+ T cell response. Proceedings of the National Academy of Sciences USA100, 7235-7240
    • (2003) Proceedings of the National Academy of Sciences USA100 , pp. 7235-7240
    • Webby, R.J.1
  • 103
    • 15244345880 scopus 로고    scopus 로고
    • Consequences of immunodominant epitope deletion for minor influenza virus-specific CD8+ -T-cell responses
    • Andreansky, S.S. et al. (2005) Consequences of immunodominant epitope deletion for minor influenza virus-specific CD8+ -T-cell responses. Journal of Virology 79, 4329-4339
    • (2005) Journal of Virology , vol.79 , pp. 4329-4339
    • Andreansky, S.S.1
  • 104
    • 32244443978 scopus 로고    scopus 로고
    • Avirus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequencies
    • La Gruta, N.L. et al. (2006) Avirus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequencies. Proceedings of the National Academy of Sciences USA 103, 994-999
    • (2006) Proceedings of the National Academy of Sciences USA , vol.103 , pp. 994-999
    • La Gruta, N.L.1
  • 105
    • 33747776472 scopus 로고    scopus 로고
    • Addition of a prominent epitope affects influenzaAvirus-specific CD8+ T cell immunodominance hierarchies when antigen is limiting
    • Jenkins, M.R. et al. (2006) Addition of a prominent epitope affects influenzaAvirus-specific CD8+ T cell immunodominance hierarchies when antigen is limiting. Journal of Immunology 177, 2917-2925
    • (2006) Journal of Immunology , vol.177 , pp. 2917-2925
    • Jenkins, M.R.1
  • 106
    • 58049208212 scopus 로고    scopus 로고
    • Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy
    • Kedzierska, K. et al. (2008) Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy. Proceedings of the National Academy of Sciences USA 105, 19408-19413
    • (2008) Proceedings of the National Academy of Sciences USA , vol.105 , pp. 19408-19413
    • Kedzierska, K.1
  • 107
    • 84879673982 scopus 로고    scopus 로고
    • Influenza Avirus infection impairs mycobacteria-specific T cell responses and mycobacterial clearance in the lung during pulmonary coinfection
    • Florido, M. et al. (2013) Influenza Avirus infection impairs mycobacteria-specific T cell responses and mycobacterial clearance in the lung during pulmonary coinfection. Journal of Immunology 191, 302-311
    • (2013) Journal of Immunology , vol.191 , pp. 302-311
    • Florido, M.1
  • 108
    • 84857719909 scopus 로고    scopus 로고
    • Comparison of influenza and SIV specific CD8 T cell responses in macaques
    • doi:10.1371/ journal.pone.0032431
    • Jegaskanda, S. et al. (2012) Comparison of influenza and SIV specific CD8 T cell responses in macaques. PLoS One 7, e32431. doi:10.1371/ journal.pone.0032431
    • (2012) PLoS One , vol.7
    • Jegaskanda, S.1
  • 109
    • 4544233308 scopus 로고    scopus 로고
    • Persistent expression of CD94/NKG2 receptors by virus-specific CD8 Tcells is initiated by TCR-mediated signals
    • Wojtasiak, M. et al. (2004) Persistent expression of CD94/NKG2 receptors by virus-specific CD8 Tcells is initiated by TCR-mediated signals. International Immunology 16, 1333-1341
    • (2004) International Immunology , vol.16 , pp. 1333-1341
    • Wojtasiak, M.1
  • 110
    • 77958536372 scopus 로고    scopus 로고
    • Timing of immune escape linked to success or failure of vaccination
    • doi:10.1371/journal.pone.0012774
    • Reece, J.C. et al. (2010) Timing of immune escape linked to success or failure of vaccination. PLoS One 5, e12774. doi:10.1371/journal.pone.0012774
    • (2010) PLoS One , vol.5
    • Reece, J.C.1
  • 111
    • 0030722677 scopus 로고    scopus 로고
    • Role of the B-cell response in recovery of mice from primary influenza virus infection
    • Gerhard,W. et al. (1997) Role of the B-cell response in recovery of mice from primary influenza virus infection. Immunological Reviews 159, 95-103
    • (1997) Immunological Reviews , vol.159 , pp. 95-103
    • Gerhard, W.1
  • 112
    • 0037392976 scopus 로고    scopus 로고
    • Antibody response to influenza infection of mice: Different patterns for glycoprotein and nucleocapsid antigens
    • Sealy, R. et al. (2003) Antibody response to influenza infection of mice: different patterns for glycoprotein and nucleocapsid antigens. Immunology 108, 431-439
    • (2003) Immunology , vol.108 , pp. 431-439
    • Sealy, R.1
  • 113
    • 84877620734 scopus 로고    scopus 로고
    • Broadly neutralizing antibodies against influenza viruses
    • Laursen, N.S. and Wilson, I.A. (2013) Broadly neutralizing antibodies against influenza viruses. Antiviral Res 98, 476-483
    • (2013) Antiviral Res , vol.98 , pp. 476-483
    • Laursen, N.S.1    Wilson, I.A.2
  • 114
    • 81555228636 scopus 로고    scopus 로고
    • Novel vaccines against influenza viruses
    • Kang, S.M., Song, J.M. and Compans, R.W. (2011) Novel vaccines against influenza viruses. Virus Research 162, 31-38
    • (2011) Virus Research , vol.162 , pp. 31-38
    • Kang, S.M.1    Song, J.M.2    Compans, R.W.3
  • 115
    • 84874270957 scopus 로고    scopus 로고
    • Addition of glycosylation to influenza A virus hemagglutinin modulates antibody-mediated recognition of H1N1 2009 pandemic viruses
    • Job, E.R. et al. (2013) Addition of glycosylation to influenza A virus hemagglutinin modulates antibody-mediated recognition of H1N1 2009 pandemic viruses. Journal of Immunology 190, 2169-2177
    • (2013) Journal of Immunology , vol.190 , pp. 2169-2177
    • Job, E.R.1
  • 116
    • 79960856413 scopus 로고    scopus 로고
    • The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease
    • Davtyan, H. et al. (2011) The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease. Journal of Translational Medicine 9, 127
    • (2011) Journal of Translational Medicine , vol.9 , pp. 127
    • Davtyan, H.1
  • 117
    • 33644515958 scopus 로고    scopus 로고
    • An unexpected antibody response to an engineered influenza virus modifies CD8+ T cell responses
    • Thomas, P.G. et al. (2006) An unexpected antibody response to an engineered influenza virus modifies CD8+ T cell responses. Proceedings of the National Academy of Sciences USA 103, 2764-2769
    • (2006) Proceedings of the National Academy of Sciences USA , vol.103 , pp. 2764-2769
    • Thomas, P.G.1
  • 118
    • 0022414281 scopus 로고
    • Attenuation of wild-type human influenza A virus by acquisition of the PA polymerase and matrix protein genes of influenza A/Ann Arbor/6/60 cold-adapted donor virus
    • Snyder, M.H. et al. (1985) Attenuation of wild-type human influenza A virus by acquisition of the PA polymerase and matrix protein genes of influenza A/Ann Arbor/6/60 cold-adapted donor virus. Journal of Clinical Microbiology 22, 719-725
    • (1985) Journal of Clinical Microbiology , vol.22 , pp. 719-725
    • Snyder, M.H.1
  • 119
    • 0022375343 scopus 로고
    • Development and characterization of cold-adapted viruses for use as live virus vaccines
    • Maassab, H.F. and DeBorde, D.C. (1985) Development and characterization of cold-adapted viruses for use as live virus vaccines. Vaccine 3, 355-369
    • (1985) Vaccine , vol.3 , pp. 355-369
    • Maassab, H.F.1    Deborde, D.C.2
  • 120
    • 0023851892 scopus 로고
    • Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccines
    • Snyder, M.H. et al. (1988) Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccines. Journal of Virology 62, 488-495
    • (1988) Journal of Virology , vol.62 , pp. 488-495
    • Snyder, M.H.1
  • 121
    • 0023934820 scopus 로고
    • Amutation in the PA protein gene of cold-adapted B/Ann Arbor/1/66 influenza virus associated with reversion of temperature sensitivity and attenuated virulence
    • Donabedian, A.M. et al. (1988)Amutation in the PA protein gene of cold-adapted B/Ann Arbor/1/66 influenza virus associated with reversion of temperature sensitivity and attenuated virulence. Virology 163, 444-451
    • (1988) Virology , vol.163 , pp. 444-451
    • Donabedian, A.M.1
  • 122
    • 0032530630 scopus 로고    scopus 로고
    • Transfectant influenza A viruses are effective recombinant immunogens in the treatment of experimental cancer
    • Restifo, N.P. et al. (1998) Transfectant influenza A viruses are effective recombinant immunogens in the treatment of experimental cancer. Virology 249, 89-97
    • (1998) Virology , vol.249 , pp. 89-97
    • Restifo, N.P.1
  • 123
    • 0034671477 scopus 로고    scopus 로고
    • Antitumor properties of influenza virus vectors
    • Zheng, H., Palese, P. and Garcia-Sastre, A. (2000) Antitumor properties of influenza virus vectors. Cancer Research 60, 6972-6976
    • (2000) Cancer Research , vol.60 , pp. 6972-6976
    • Zheng, H.1    Palese, P.2    Garcia-Sastre, A.3
  • 124
    • 0034331140 scopus 로고    scopus 로고
    • Efficient expression of the tumor-associated antigen MAGE-3 in human dendritic cells, using an avian influenza virus vector
    • Strobel, I. et al. (2000) Efficient expression of the tumor-associated antigen MAGE-3 in human dendritic cells, using an avian influenza virus vector. Human Gene Therapy 11, 2207-2218
    • (2000) Human Gene Therapy , vol.11 , pp. 2207-2218
    • Strobel, I.1
  • 125
    • 0027494094 scopus 로고
    • Chimeric influenza virus induces neutralizing antibodies and cytotoxic Tcells against human immunodeficiency virus type 1
    • Li, S. et al. (1993) Chimeric influenza virus induces neutralizing antibodies and cytotoxic Tcells against human immunodeficiency virus type 1. Journal of Virology 67, 6659-6666
    • (1993) Journal of Virology , vol.67 , pp. 6659-6666
    • Li, S.1
  • 126
    • 0031725117 scopus 로고    scopus 로고
    • Chimeric influenza virus replicating predominantly in the murine upper respiratory tract induces local immune responses against human immunodeficiency virus type 1 in the genital tract
    • Ferko, B. et al. (1998) Chimeric influenza virus replicating predominantly in the murine upper respiratory tract induces local immune responses against human immunodeficiency virus type 1 in the genital tract. Journal of Infectious Diseases 178, 1359-1368
    • (1998) Journal of Infectious Diseases , vol.178 , pp. 1359-1368
    • Ferko, B.1
  • 127
    • 0028853959 scopus 로고
    • Mucosal model of immunization against human immunodeficiency virus type 1 with a chimeric influenza virus
    • Muster, T. et al. (1995) Mucosal model of immunization against human immunodeficiency virus type 1 with a chimeric influenza virus. Journal of Virology 69, 6678-6686
    • (1995) Journal of Virology , vol.69 , pp. 6678-6686
    • Muster, T.1
  • 128
    • 10744227393 scopus 로고    scopus 로고
    • Induction of protective immunity against malaria by primingboosting immunization with recombinant coldadapted influenza and modified vaccinia Ankara viruses expressing a CD8 + -T-cell epitope derived from the circumsporozoite protein of Plasmodium yoelii
    • Gonzalez-Aseguinolaza, G. et al. (2003) Induction of protective immunity against malaria by primingboosting immunization with recombinant coldadapted influenza and modified vaccinia Ankara viruses expressing a CD8 + -T-cell epitope derived from the circumsporozoite protein of Plasmodium yoelii. Journal of Virology 77, 11859-11866
    • (2003) Journal of Virology , vol.77 , pp. 11859-11866
    • Gonzalez-Aseguinolaza, G.1
  • 129
    • 0031064918 scopus 로고    scopus 로고
    • Chimeric influenza viruses incorporating epitopes of outer membrane protein F as a vaccine against pulmonary infection with Pseudomonas aeruginosa
    • Gilleland, H.E., Jr. et al. (1997) Chimeric influenza viruses incorporating epitopes of outer membrane protein F as a vaccine against pulmonary infection with Pseudomonas aeruginosa. Behring Institute of Mitteilungen 98, 291-301
    • (1997) Behring Institute of Mitteilungen , vol.98 , pp. 291-301
    • Gilleland Jr., H.E.1
  • 130
    • 0031870999 scopus 로고    scopus 로고
    • A chimeric influenza virus expressing an epitope of outer membrane protein F of Pseudomonas aeruginosa affords protection against challenge with P. Aeruginosa in a murine model of chronic pulmonary infection
    • Staczek, J. et al. (1998) A chimeric influenza virus expressing an epitope of outer membrane protein F of Pseudomonas aeruginosa affords protection against challenge with P. aeruginosa in a murine model of chronic pulmonary infection. Infection and Immunity 66, 3990-3994
    • (1998) Infection and Immunity , vol.66 , pp. 3990-3994
    • Staczek, J.1
  • 131
    • 0034690637 scopus 로고    scopus 로고
    • Diversity of envelope glycoprotein from human immunodeficiency virus type 1 of recent seroconverters in Thailand
    • McCutchan, F.E. et al. (2000) Diversity of envelope glycoprotein from human immunodeficiency virus type 1 of recent seroconverters in Thailand. AIDS Research and Human Retroviruses 16, 801-805
    • (2000) AIDS Research and Human Retroviruses , vol.16 , pp. 801-805
    • McCutchan, F.E.1
  • 132
    • 0035162494 scopus 로고    scopus 로고
    • Evolutionary and immunological implications of contemporary HIV-1 variation
    • Korber, B. et al. (2001) Evolutionary and immunological implications of contemporary HIV- 1 variation. British Medical Bulletin 58, 19-42
    • (2001) British Medical Bulletin , vol.58 , pp. 19-42
    • Korber, B.1
  • 133
    • 77955512306 scopus 로고    scopus 로고
    • New approaches to design HIV-1 T-cell vaccines
    • Perrin, H. et al. (2010) New approaches to design HIV-1 T-cell vaccines. Current Opinion in HIV and AIDS 5, 368-376
    • (2010) Current Opinion in HIV and AIDS , vol.5 , pp. 368-376
    • Perrin, H.1
  • 134
    • 73349094086 scopus 로고    scopus 로고
    • Vaccination with ALVACand AIDSVAXto prevent HIV-1 infection in Thailand
    • Rerks-Ngarm, S. et al. (2009) Vaccination with ALVACand AIDSVAXto prevent HIV-1 infection in Thailand. New England Journal of Medicine 361, 2209-2220
    • (2009) New England Journal of Medicine , vol.361 , pp. 2209-2220
    • Rerks-Ngarm, S.1
  • 135
    • 79952083300 scopus 로고    scopus 로고
    • The development of an AIDS mucosal vaccine
    • Tang, X. and Chen, Z. (2010) The development of an AIDS mucosal vaccine. Viruses 2, 283-297
    • (2010) Viruses , vol.2 , pp. 283-297
    • Tang, X.1    Chen, Z.2
  • 136
    • 0038279752 scopus 로고    scopus 로고
    • Prime-boost immunization schedules based on influenza virus and vaccinia virus vectors potentiate cellular immune responses against human immunodeficiency virus Env protein systemically and in the genitorectal draining lymph nodes
    • Gherardi, M.M. et al. (2003) Prime-boost immunization schedules based on influenza virus and vaccinia virus vectors potentiate cellular immune responses against human immunodeficiency virus Env protein systemically and in the genitorectal draining lymph nodes. Journal of Virology 77, 7048-7057
    • (2003) Journal of Virology , vol.77 , pp. 7048-7057
    • Gherardi, M.M.1
  • 137
    • 4143115661 scopus 로고    scopus 로고
    • Induction of cellular immune responses to simian immunodeficiency virus gag by two recombinant negative-strand RNAvirus vectors
    • Nakaya, Y. et al. (2004) Induction of cellular immune responses to simian immunodeficiency virus gag by two recombinant negative-strand RNAvirus vectors. Journal of Virology 78, 9366-9375
    • (2004) Journal of Virology , vol.78 , pp. 9366-9375
    • Nakaya, Y.1
  • 138
    • 3543078012 scopus 로고    scopus 로고
    • HIV and SIV CTL escape: Implications for vaccine design
    • Goulder, P.J. and Watkins, D.I. (2004) HIV and SIV CTL escape: implications for vaccine design. Nature Reviews Immunology 4, 630-640
    • (2004) Nature Reviews Immunology , vol.4 , pp. 630-640
    • Goulder, P.J.1    Watkins, D.I.2
  • 140
    • 0035735632 scopus 로고    scopus 로고
    • Anti-influenza virus drug design: Sialidase inhibitors
    • Itzstein, J.C.D.a.M.v. (2001) Anti-influenza virus drug design: sialidase inhibitors. Australian Journal of Chemistry 54, 663-670
    • (2001) Australian Journal of Chemistry , vol.54 , pp. 663-670
    • Itzstein, J.C.D.A.M.V.1
  • 142
    • 84875980586 scopus 로고    scopus 로고
    • Global assessment of resistance to neuraminidase inhibitors, 2008-2011: The Influenza Resistance Information Study (IRIS)
    • Whitley, R.J. et al. (2013) Global assessment of resistance to neuraminidase inhibitors, 2008-2011: the Influenza Resistance Information Study (IRIS). Clinical Infectious Disease 56, 1197-1205
    • (2013) Clinical Infectious Disease , vol.56 , pp. 1197-1205
    • Whitley, R.J.1
  • 143
    • 84883376291 scopus 로고    scopus 로고
    • Resistance to neuraminidase inhibitors conferred by an R292 K mutation in a human influenza virus H7N9 isolate can be masked bya mixed R/K viral population
    • doi: 10.1128/mBio.00396-13
    • Yen, H.L. et al. (2013) Resistance to neuraminidase inhibitors conferred by an R292 K mutation in a human influenza virus H7N9 isolate can be masked bya mixed R/K viral population. MBio 4, e00396-13. doi: 10.1128/mBio.00396-13
    • (2013) MBio , vol.4
    • Yen, H.L.1
  • 144
    • 12944314951 scopus 로고    scopus 로고
    • Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations
    • Abed, Y., Goyette, N. and Boivin, G. (2005) Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations. Antimicrobial Agents and Chemotherapy 49, 556-559
    • (2005) Antimicrobial Agents and Chemotherapy , vol.49 , pp. 556-559
    • Abed, Y.1    Goyette, N.2    Boivin, G.3
  • 145
    • 33845637926 scopus 로고    scopus 로고
    • Impact of neuraminidase mutations conferring influenza resistance to neuraminidase inhibitors in the N1 and N2 genetic backgrounds
    • Abed, Y., Baz, M. and Boivin, G. (2006) Impact of neuraminidase mutations conferring influenza resistance to neuraminidase inhibitors in the N1 and N2 genetic backgrounds. Antiviral Therapy 11, 971-976
    • (2006) Antiviral Therapy , vol.11 , pp. 971-976
    • Abed, Y.1    Baz, M.2    Boivin, G.3
  • 146
    • 79851471047 scopus 로고    scopus 로고
    • Generation and characterization of recombinant pandemic influenza A(H1N1) viruses resistant to neuraminidase inhibitors
    • Pizzorno, A. et al. (2011) Generation and characterization of recombinant pandemic influenza A(H1N1) viruses resistant to neuraminidase inhibitors. Journal of Infectious Diseases 203, 25-31
    • (2011) Journal of Infectious Diseases , vol.203 , pp. 25-31
    • Pizzorno, A.1
  • 147
    • 67349177735 scopus 로고    scopus 로고
    • The origin and global emergence of adamantane resistant A/H3N2 influenza viruses
    • Nelson, M.I. et al. (2009) The origin and global emergence of adamantane resistant A/H3N2 influenza viruses. Virology 388, 270-278
    • (2009) Virology , vol.388 , pp. 270-278
    • Nelson, M.I.1
  • 148
    • 0035865919 scopus 로고    scopus 로고
    • Selection of influenza virus mutants in experimentally infected volunteers treated with oseltamivir
    • Gubareva, L.V. et al. (2001) Selection of influenza virus mutants in experimentally infected volunteers treated with oseltamivir. Journal of Infectious Diseases 183, 523-531
    • (2001) Journal of Infectious Diseases , vol.183 , pp. 523-531
    • Gubareva, L.V.1
  • 149
    • 0036894107 scopus 로고    scopus 로고
    • Mechanism by which mutations at his274 alter sensitivity of influenza a virus n1 neuraminidase to oseltamivir carboxylate and zanamivir
    • Wang, M.Z., Tai, C.Y. and Mendel, D.B. (2002) Mechanism by which mutations at his274 alter sensitivity of influenza a virus n1 neuraminidase to oseltamivir carboxylate and zanamivir. Antimicrobial Agents and Chemotherapy 46, 3809-3816
    • (2002) Antimicrobial Agents and Chemotherapy , vol.46 , pp. 3809-3816
    • Wang, M.Z.1    Tai, C.Y.2    Mendel, D.B.3
  • 150
    • 78650978283 scopus 로고    scopus 로고
    • Comprehensive assessment of 2009 pandemic influenza A (H1N1) virus drug susceptibility in vitro
    • Gubareva, L.V. et al. (2010) Comprehensive assessment of 2009 pandemic influenza A (H1N1) virus drug susceptibility in vitro. Antiviral Therapy 15, 1151-1159
    • (2010) Antiviral Therapy , vol.15 , pp. 1151-1159
    • Gubareva, L.V.1
  • 151
    • 0030028671 scopus 로고    scopus 로고
    • Characterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidino-Neu5Ac2en
    • Gubareva, L.V. et al. (1996) Characterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidino-Neu5Ac2en. Journal of Virology 70, 1818-1827
    • (1996) Journal of Virology , vol.70 , pp. 1818-1827
    • Gubareva, L.V.1
  • 152
    • 79951506684 scopus 로고    scopus 로고
    • The I222 v neuraminidase mutation has a compensatory role in replication of an oseltamivir-resistant influenza virus A/H3N2 E119 Vmutant
    • Simon, P. et al. (2011) The I222 V neuraminidase mutation has a compensatory role in replication of an oseltamivir-resistant influenza virus A/H3N2 E119 Vmutant. Journal of Clinical Microbiology 49, 715-717
    • (2011) Journal of Clinical Microbiology , vol.49 , pp. 715-717
    • Simon, P.1
  • 153
    • 77954889069 scopus 로고    scopus 로고
    • Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus
    • Manicassamy, B. et al. (2010) Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus. Proceedings of the National Academy of Sciences USA 107, 11531-11536
    • (2010) Proceedings of the National Academy of Sciences USA , vol.107 , pp. 11531-11536
    • Manicassamy, B.1
  • 154
    • 2942534218 scopus 로고    scopus 로고
    • Rescue of influenza virus expressing GFP from the NS1 reading frame
    • Kittel, C. et al. (2004) Rescue of influenza virus expressing GFP from the NS1 reading frame. Virology 324, 67-73
    • (2004) Virology , vol.324 , pp. 67-73
    • Kittel, C.1
  • 155
    • 0032948081 scopus 로고    scopus 로고
    • The first case of H5N1 avian influenza infection in a human with complications of adult respiratory distress syndrome and Reye's syndrome
    • Ku, A.S. and Chan, L.T. (1999) The first case of H5N1 avian influenza infection in a human with complications of adult respiratory distress syndrome and Reye's syndrome. Journal of Paediatrics and Child Health 35, 207-209
    • (1999) Journal of Paediatrics and Child Health , vol.35 , pp. 207-209
    • Ku, A.S.1    Chan, L.T.2
  • 156
    • 84856159569 scopus 로고    scopus 로고
    • Pause on avian flu transmission studies
    • Fouchier, R.A., Garcia-Sastre, A. and Kawaoka, Y. (2012) Pause on avian flu transmission studies. Nature 481, 443
    • (2012) Nature , vol.481 , pp. 443
    • Fouchier, R.A.1    Garcia-Sastre, A.2    Kawaoka, Y.3
  • 157
    • 84862618108 scopus 로고    scopus 로고
    • Airborne transmission of influenza A/H5N1 virus between ferrets
    • Herfst, S. et al. (2012) Airborne transmission of influenza A/H5N1 virus between ferrets. Science 336, 1534-1541
    • (2012) Science , vol.336 , pp. 1534-1541
    • Herfst, S.1
  • 158
    • 84861394598 scopus 로고    scopus 로고
    • Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets
    • Imai, M. et al. (2012) Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets. Nature 486, 420-428
    • (2012) Nature , vol.486 , pp. 420-428
    • Imai, M.1
  • 159
    • 84877976470 scopus 로고    scopus 로고
    • Establishment of Vero cell RNA polymerase I-driven reverse genetics for Influenza A virus and its application for pandemic (H1N1) 2009 influenza virus vaccine production
    • Song, M.S. et al. (2013) Establishment of Vero cell RNA polymerase I-driven reverse genetics for Influenza A virus and its application for pandemic (H1N1) 2009 influenza virus vaccine production. Journal of General Virology 94(Pt 6), 1230-1235
    • (2013) Journal of General Virology , vol.94 , Issue.PART 6 , pp. 1230-1235
    • Song, M.S.1
  • 160
    • 84875475566 scopus 로고    scopus 로고
    • High yield production of influenza virus in Madin Darby canine kidney (MDCK) cells with stable knockdownof IRF7
    • doi: 10.1371/journal.pone.0059892
    • Hamamoto, I. et al. (2013) High yield production of influenza virus in Madin Darby canine kidney (MDCK) cells with stable knockdownof IRF7. PLoS One 8, e59892. doi: 10.1371/journal.pone.0059892
    • (2013) PLoS One , vol.8
    • Hamamoto, I.1
  • 161
    • 84863011522 scopus 로고    scopus 로고
    • Pause on avian flu transmission research
    • Fouchier, R.A. et al. (2012) Pause on avian flu transmission research. Science 335, 400-401
    • (2012) Science , vol.335 , pp. 400-401
    • Fouchier, R.A.1
  • 162
    • 84873095868 scopus 로고    scopus 로고
    • Transmission studies resume for avian flu
    • Fouchier, R.A. et al. (2013) Transmission studies resume for avian flu. Science 339, 520-521
    • (2013) Science , vol.339 , pp. 520-521
    • Fouchier, R.A.1
  • 163
    • 84877785371 scopus 로고    scopus 로고
    • Human infection with a novel avian-origin influenza A (H7N9) virus
    • Gao, R. et al. (2013) Human infection with a novel avian-origin influenza A (H7N9) virus. New England Journal of Medicine 368, 1888-1897
    • (2013) New England Journal of Medicine , vol.368 , pp. 1888-1897
    • Gao, R.1
  • 164
    • 84885660826 scopus 로고    scopus 로고
    • Characterization of H7N9 influenza A viruses isolated from humans
    • Watanabe, T. et al. (2013) Characterization of H7N9 influenza A viruses isolated from humans. Nature 501, 551-555
    • (2013) Nature , vol.501 , pp. 551-555
    • Watanabe, T.1
  • 166
  • 167
    • 84893438707 scopus 로고    scopus 로고
    • A versatile RNA vector for delivery of coding and non-coding RNAs
    • Schmid, S., Zony, L.C. and Tenoever, B.R. (2013) A versatile RNA vector for delivery of coding and non-coding RNAs. Journal of Virology 88, 2333-2336
    • (2013) Journal of Virology , vol.88 , pp. 2333-2336
    • Schmid, S.1    Zony, L.C.2    Tenoever, B.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.