A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity

Journal of Virology

Volumn 79, Issue 17, 2005, Pages 11533-11536

  Glaser, Laurel ^a   Stevens, James ^b   Zamarin, Dmitriy ^a   Wilson, Ian A ^b   García Sastre, Adolfo ^a   Tumpey, Terrence M ^d   Basler, Christopher F ^a   Taubenberger, Jeffery K ^c   Palese, Peter ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

^d NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CELL RECEPTOR; HEMAGGLUTININ; SIALIC ACID;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; AVIAN INFLUENZA; BINDING SITE; CONSENSUS SEQUENCE; CONTROLLED STUDY; EMBRYO; GENE MUTATION; GENETIC CONSERVATION; HOST RESISTANCE; HUMAN; HUMAN CELL; INFLUENZA; INFLUENZA VIRUS; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; STRAIN DIFFERENCE; VIRUS CELL INTERACTION;

AMINO ACID SUBSTITUTION; ANIMALS; CHICKENS; ERYTHROCYTES; HEMAGGLUTINATION TESTS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; N-ACETYLNEURAMINIC ACID; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRIDAE INFECTIONS; RECEPTORS, VIRUS; SPECIES SPECIFICITY;

AVES; INFLUENZA VIRUS;

EID: 23844487765     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.17.11533-11536.2005     Document Type: Article

References (28)

1. Brownlee, G. G., and E. Fodor. 2001. The predicted antigenicity of the haemagglutinin of the 1918 Spanish influenza pandemic suggests an avian origin. Philos. Trans. R Soc. Lond. B Biol. Sci. 356:1871-1876.
2. Connor, R. J., Y. Kawaoka, R. G. Webster, and J. C. Paulson. 1994. Receptor specificity in human, avian, and equine H2 and H3 influenza virus isolates. Virology 205:17-23.
3. Couceiro, J. N., J. C. Paulson, and L. G. Baum. 1993. Influenza virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium; the role of the host cell in selection of hemagglutinin receptor specificity. Virus Res. 29:155-165.
4. Fanning, T. G., R. D. Slemons, A. H. Reid, T. A. Janczewski, J. Dean, and J. K. Taubenberger. 2002, 1917 avian influenza virus sequences suggest that the 1918 pandemic virus did not acquire its hemagglutinin directly from birds. J. Virol. 76:7860-7862.
5. Gambaryan, A. S., J. S. Robertson, and M. N. Matrosovich. 1999. Effects of egg-adaptation on the receptor-binding properties of human influenza A and B viruses. Virology 258:232-239.
6. Gambaryan, A. S., A. B. Tuzikov, N. V. Bovin, S. S. Yamnikova, D. K. Lvov, R. G. Webster, and M. N. Matrosovich. 2003. Differences between influenza virus receptors on target cells of duck and chicken and receptor specificity of the 1997 H5N1 chicken and human influenza viruses from Hong Kong. Avian Dis. 47:1154-1160.
7. Gambaryan, A. S., A. B. Tuzikov, V. E. Piskarev, S. S. Yamnikova, D. K. Lvov, J. S. Robertson, N. V. Bovin, and M. N. Matrosovich. 1997. Specification of receptor-binding phenotypes of influenza virus isolates from different hosts using synthetic sialylglycopolymers: non-egg-adapted human H1 and H3 influenza A and influenza B viruses share a common high binding affinity for 6′-sialyl(N-acetyllactosamine). Virology 232:345-350.
8. Gamblin, S. J., L. F. Haire, R. J. Russell, D. J. Stevens, B. Xiao, Y. Ha, N. Vasisht, D. A. Steinhauer, R. S. Daniels, A. Elliot, D. C. Wiley, and J. J. Skehel. 2004. The structure and receptor binding properties of the 1918 influenza hemagglutinin. Science 303:1838-1842.
9. Ito, T., J. N. Couceiro, S. Kelm, L. G. Baum, S. Krauss, M. R. Castrucci, I. Donatelli, H. Kida, J. C. Paulson, R. G. Webster, and Y. Kawaoka. 1998. Molecular basis for the generation in pigs of influenza A viruses with pandemic potential. J. Virol. 72:7367-7373.
10. Johnson, N. P., and J. Mueller. 2002. Updating the accounts: global mortality of the 1918-1920 "Spanish" influenza pandemic. Bull. Hist. Med. 76:105-115.
11. Kobasa, D., A. Takada, K. Shinya, M. Hatta, P. Halfmann, S. Theriault, H. Suzuki, H. Nishimura, K. Mitamura, N. Sugaya, T. Usui, T. Murata, Y. Maeda, S. Watanabe, M. Suresh, T. Suzuki, Y. Suzuki, H. Feldmann, and Y. Kawaoka. 2004. Enhanced virulence of influenza A viruses with the haem-agglutinin of the 1918 pandemic virus. Nature 431:703-707.
12. Laver, W. G., N. Bischofberger, and R. G. Webster. 2000. The origin and control of pandemic influenza. Perspect. Biol. Med. 43:173-192.
13. Matrosovich, M., A. Tuzikov, N. Bovin, A. Gambaryan, A. Klimov, M. R. Castrucci, I. Donatelli, and Y. Kawaoka. 2000. Early alterations of the receptor-binding properties of H1, H2, and H3 avian influenza virus hemagglutinins after their introduction into mammals. J. Virol. 74:8502-8512.
14. Matrosovich, M. N., A. S. Gambaryan, S. Teneberg, V. E. Piskarev, S. S. Yamnikova, D. K. Lvov, J. S. Robertson, and K. A. Karlsson. 1997. Avian influenza A viruses differ from human viruses by recognition of sialyloligo-saccharides and gangliosides and by a higher conservation of the HA receptor-binding site. Virology 233:224-234.
15. Matrosovich, M. N., A. S. Gambaryan, A. B. Tuzikov, N. E. Byramova, L. V. Mochalova, A. A. Golbraikh, M. D. Shenderovich, J. Finne, and N. V. Bovin. 1993. Probing of the receptor-binding sites of the H1 and H3 influenza A and influenza B virus hemagglutinins by synthetic and natural sialosides. Virology 196:111-121.
16. Matrosovich, M. N., S. Krauss, and R. G. Webster. 2001. H9N2 influenza A viruses from poultry in Asia have human virus-like receptor specificity. Virology 281:156-162.
17. Mochalova, L., A. Gambaryan, J. Romanova, A. Tuzikov, A. Chinarev, D. Katinger, H. Katinger, A. Egorov, and N. Bovin. 2003. Receptor-binding properties of modern human influenza viruses primarily isolated in Vero and MDCK cells and chicken embryonated eggs. Virology 313:473-480.
18. Murrell, M., M. Porotto, T. Weber, O. Greengard, and A. Moscona. 2003. Mutations in human parainfluenza virus type 3 hemagglutinin-neuraminidase causing increased receptor binding activity and resistance to the transition state sialic acid analog 4-GU-DANA (Zanamivir). J. Virol. 77:309-317.
19. Nobusawa, E., H. Ishihara, T. Morishita, K. Sato, and K. Nakajima. 2000. Change in receptor-binding specificity of recent human influenza A viruses (H3N2): a single amino acid change in hemagglutinin altered its recognition of sialyloligosaccharides. Virology 278:587-596.
20. Ohuchi, M., A. Feldmann, R. Ohuchi, and H. D. Klenk. 1995. Neuraminidase is essential for fowl plague virus hemagglutinin to show hemagglutinating activity. Virology 212:77-83.
21. Paragas, J., J. Talon, R. E. O'Neill, D. K. Anderson, A. Garcia-Sastre, and P. Palese. 2001. Influenza B and C virus NEP (NS2) proteins possess nuclear export activities. J. Virol. 75:7375-7383.
22. Paulson, J. C., and G. N. Rogers. 1987. Resialylated erythrocytes for assessment of the specificity of sialyloligosaccharide binding proteins. Methods Enzymol. 138:162-168.
23. Reid, A. H., T. G. Fanning, J. V. Hultin, and J. K. Taubenberger. 1999. Origin and evolution of the 1918 "Spanish" influenza virus hemagglutinin gene. Proc. Natl. Acad. Sci. USA 96:1651-1656.
24. Reid, A. H., T. A. Janczewski, R. M. Lourens, A. J. Elliot, R. S. Daniels, C. L. Berry, J. S. Oxford, and J. K. Taubenberger. 2003. 1918 Influenza pandemic caused by highly conserved viruses with two receptor-binding variants. Emerg. Infect. Dis. 9:1249-1253.
25. Rogers, G. N., and B. L. D'Souza. 1989. Receptor binding properties of human and animal H1 influenza virus isolates. Virology 173:317-322.
26. Stevens, J., A. L. Corper, C. F. Basler, J. K. Taubenberger, P. Palese, and I. A. Wilson. 2004. Structure of the uncleaved human H1 hemagglutinin from the extinct 1918 influenza virus. Science 303:1866-1870.
27. Tumpey, T. M., A. Garcia-Sastre, A. Mikulasova, J. K. Taubenberger, D. E. Swayne, P. Palese, and C. F. Basler. 2002. Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus. Proc. Natl. Acad. Sci. USA 99:13849-13854.
28. Winter, G., S. Fields, and G. G. Brownlee. 1981. Nucleotide sequence of the haemagglutinin gene of a human influenza virus Hl subtype. Nature 292:72-75.