Large-scale sequence analysis of avian influenza isolates

Science

Volumn 311, Issue 5767, 2006, Pages 1576-1580

  Obenauar, John C ^a   Denson, Jackie ^a   Mehta, Perdeep K ^a   Su, Xiaoping ^a   Mukatira, Suraj ^a   Finkelstein, David B ^a   Xu, Xiequn ^a   Wang, Jinhua ^a   Ma, Jing ^a   Fan, Yiping ^a   Rakestraw, Karen M ^a   Webster, Robert Q ^a,b   Hoffmann, Erich ^a   Krauss, Scott ^a   Zheng, Jie ^a   Zhang, Ziwei ^a   Naeve, Clayton W ^a,b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; HEALTH CARE; MUTAGENESIS;

AVIAN INFLUENZA VIRUSES (AIVS); PANDEMIC; PERSISTENT GENOTYPES;

VIRUSES;

VIRUS PROTEIN;

INFLUENZA;

ALLELE; ARTICLE; AVIAN INFLUENZA; CHINA; EPIDEMIC; EUROPE; GENE MUTATION; GENOTYPE; INFLUENZA VIRUS A; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; VIRUS GENOME; VIRUS VIRULENCE;

ANIMALS; BIRDS; COMPUTATIONAL BIOLOGY; GENES, VIRAL; GENOME, VIRAL; HUMANS; INFLUENZA A VIRUS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H2N2 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA A VIRUS, H3N8 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA A VIRUS, H5N2 SUBTYPE; INFLUENZA A VIRUS, H7N7 SUBTYPE; INFLUENZA A VIRUS, H9N2 SUBTYPE; INFLUENZA IN BIRDS; INFLUENZA, HUMAN; MOLECULAR SEQUENCE DATA; MUTATION; PHYLOGENY; REASSORTANT VIRUSES; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; VIRAL NONSTRUCTURAL PROTEINS; VIRAL PROTEINS; VIRULENCE FACTORS;

AVES; AVIAN INFLUENZA VIRUS; INFLUENZAVIRUS A;

EID: 33645067624     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1121586     Document Type: Article

References (23)

1. T. Horimoto, Y. Kawaoka, Nat. Rev. Microbiol. 3, 591 (2005).
2. The World Health Organization maintains an updated Web site of the human H5N1 cases and deaths at www.who.int/csr/disease/avian_influenza/country. The figures given here are from the 5 January 2006 update.
3. J. Liu et al., Science 309, 1206 (2005).
4. H. Chen et al., Nature 436, 191 (2005).
5. M. Enserink, Science 310, 209 (2005).
6. Information on materials and methods is available as supporting material on Science Online.
7. P. Richterich, Genome Res. 8, 251 (1998).
8. Z. Yang, Comput. Appl. Biosci. 13, 555 (1997).
9. W. Chen et al., Nat. Med. 7, 1306 (2001).
10. Y. Kawaoka et al., Virus Res. 55, 143 (1998).
11. B. W. J. Mahy, in Genetics of Influenza Viruses, D. W. Kingsbury, P. Palese, Eds. (Springer-Verlag, Berlin, 1983), pp. 192-254.
12. R. M. Krug et al., Virology 309, 181 (2003).
13. S. Schultz-Cherry et al., J. Virol. 75, 7875 (2001).
14. A. Garcia-Sastre et al., Virology 252, 324 (1998).
15. S. H. Seo, R. G. Webster, Virus Res. 103, 107 (2004).
16. G. K. Geiss et al., Prac. Natl. Acad. Sci. U.S.A. 99, 10736 (2002).
17. A. S. Lipatov et al., J. Gen. Virol. 86, 1121 (2005).
18. Z. Songyang et al., Science 275, 73 (1997).
19. M. Sheng, C. Sala, Annu. Rev. Neurosci. 24, 1 (2001).
20. Single-letter abbreviations for the amino acid residues are as follows: A, Ala; C, Cys; D, Asp; E, Glu; F, Phe; G, Gly; H, His; I, Ile; K, Lys; L, Leu; M, Met; N, Asn; P, Pro; Q, Gln; R, Arg; S, Ser; T, Thr; V, Val; W, Trp; and Y, Tyr.
21. K. Wuthrich, Nat. Struct. Biol. 7, 188 (2000).
22. H.-C. Wong et al., Mol. Cell 12, 1251 (2003).
23. We thank the following Hartwell Center staff for superb support: J. Armstrong, S. Tate, and C. Aldridge (HT Sequencing); M. Sanyang (Software Development); S. Olsen, P. Rodrigues, and B. Cassell (Macromolecular Synthesis); and S. Malone and B. Pappas (Operations). Sequences from this study have been deposited in GenBank under accession numbers CY003847 to CY006042. This work was supported by the American Lebanese Syrian Associated Charities, a Cancer Center Support Grant (CA 21765), the U.S. Public Health Service (grant AI95357), and the Hartwell Foundation.