Sequence variation in a newly identified HLA-B35-restricted epitope in the influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes

Journal of Virology

Volumn 76, Issue 5, 2002, Pages 2567-2572

  Boon, A C M ^a   De Mutsert, G ^a   Graus, Y M F ^a   Fouchier, R A M ^a   Sintnicolaas, K ^a   Osterhaus, A D M E ^a   Rimmelzwaan, G F ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HLA B35 ANTIGEN; VIRUS NUCLEOPROTEIN;

AMINO ACID SEQUENCE; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GENETIC VARIABILITY; IMMUNITY; INFLUENZA VIRUS A; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; VIRUS STRAIN;

AMINO ACID SEQUENCE; ANTIGENIC VARIATION; EPITOPES; HLA-B35 ANTIGEN; HUMANS; INFLUENZA A VIRUS; MOLECULAR SEQUENCE DATA; NUCLEOPROTEINS; RNA-BINDING PROTEINS; T-LYMPHOCYTES, CYTOTOXIC; VIRAL CORE PROTEINS;

EID: 0036168233     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.76.5.2567-2572.2002     Document Type: Article

References (35)

1. Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope
2. Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells
3. The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype
4. Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
5. Unusually high frequency of Epstein-Barr virus genetic variants in Papua New Guinea that can escape cytotoxic T-cell recognition: Implications for virus evolution
6. Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus
7. Impaired cytotoxic T lymphocyte recognition due to genetic variations in the main immunogenic region of the human immunodeficiency virus 1 NEF protein
8. + population
9. T cell responses and virus evolution: Loss of HLA A11-restricted CTL epitopes in Epstein-Barr virus isolates from highly A11-positive populations by selective mutation of anchor residues
10. An HLA-B35-restricted epitope modified at an anchor residue results in an antagonist peptide
11. Identification of amino acid residues of influenza virus nucleoprotein essential for RNA binding
12. An Epstein-Barr virus deletion mutant associated with fatal lymphoproliferative disease unresponsive to therapy with virus-specific CTLs
13. Evolution and transmission of stable CTL escape mutations in HIV infection
14. Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS
15. + memory T cells by viral variants
16. The effects of natural altered peptide ligands on the whole blood cytotoxic T lymphocyte response to human immunodeficiency virus
17. Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants
18. Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes
19. Virus escape from CTL recognition
20. A human CTL recognizes a caspase-8-derived peptide on autologous HLAB*3503 molecules and two unrelated peptides on allogeneic HLA-B*3501 molecules
21. Immunogenic HIV variant peptides that bind to HLA-B8 can fail to stimulate cytotoxic T lymphocyte responses
22. How viruses escape from cytotoxic T lymphocytes: Molecular parameters and players
23. Influenza A virusa model for viral antigen presentation to cytotoxic T lymphocytes
24. Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains
25. The influence of antigenic variation on cytotoxic T lymphocyte responses in HIV-1 infection
26. Viral escape by selection of cytotoxic T cell-resistant variants in influenza A virus pneumonia
27. Cytotoxic T lymphocyte responses to human immunodeficiency virus: Control and escape
28. Analysis of the evolution and variation of the human influenza A virus nucleoprotein gene from 1933 to 1990
29. HLA-B*3501-peptide interactions: Role of anchor residues of peptides in their binding to HLA-B*3501 molecules
30. + CTL epitope on the NS1 protein
31. An HLA class I peptidebinding assay based on competition for binding to class I molecules on intact human B cells. Identification of conserved HIV-1 polymerase peptides binding to HLA-A*0301
32. Antigen processing for MHC class I restricted presentation of exogenous influenza A virus nucleoprotein by B-lymphoblastoid cells
33. Antigenic drift in the influenza A virus (H3N2) nucleoprotein and escape from recognition by cytotoxic T lymphocytes
34. Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant