PDZ domains and the organization of supramolecular complexes

Annual Review of Neuroscience

Volumn 24, Issue , 2001, Pages 1-29

  Sheng, M ^a   Sala, C ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

INAD PSD 95; Postsynaptic density; Protein targeting; Scaffold protein

Indexed keywords

CELL PROTEIN; PDZ PROTEIN; UNCLASSIFIED DRUG;

BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL JUNCTION; COMPLEX FORMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; REVIEW; SYNAPSE;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; HUMANS; NERVE TISSUE PROTEINS; PEPTIDES; PROTEINS;

EID: 0034916230     PISSN: 0147006X     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.neuro.24.1.1     Document Type: Review

References (143)

1. Interaction of eye protein kinase C and INAD in Drosophila. Localization of binding domains and electrophysiological characterization of a loss of association in transgenic flies
2. Postsynaptic scaffolds of excitatory and inhibitory synapses in hippocampal neurons: Maintenance components independent of actin filaments and microtubules
3. The visual G protein of fly photoreceptors interacts with the PDZ domain assembled INAD signaling complex via direct binding of activated Galpha(q) to phospholipase cbeta
4. APC: The plot thickens
5. Localization of apical epithelial determinants by the basolateral PDZ protein Scribble
6. Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting
7. Sorting out genes that regulate epithelial and neuronal polarity
8. Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and α 1-syntrophin mediated by PDZ domains
9. Cloning and characterization of postsynaptic density 93, a nitric oxide synthase interacting protein
10. Localization of postsynaptic density-93 to dendritic microtubules and interaction with microtubule-associated protein 1A
11. EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains
12. Junction genetics
13. Regulation of synapse structure and function by the Drosophila tumor suppressor gene dlg
14. A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain
15. A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor
16. A synaptic RasGTPase activating protein inhibited by CaM kinase II
17. Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex
18. Function of p55 and its non-erythroid homologues
19. The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein
20. Human Cask/Lin-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cells
21. + channel Kir 2.3 to PSD-95 is regulated by protein kinase A phosphorylation
22. Activity and synaptic receptor targeting: The long view
23. Synaptic targeting of the postsynaptic density protein PSD-95 mediated by lipid and protein motifs
24. Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition
25. BEGAIN (brain-enriched guanylate kinase-associated protein), a novel neuronal PSD-95/SAP90-binding protein
26. MAGI-1, a membrane-associated guanylate kinase with a unique arrangement of protein-protein interaction domains
27. GRIP: A synaptic PDZ domain-containing protein that interacts with AMPA receptors
28. Characterization of the glutamate receptor-interacting proteins GRIP1 and GRIP2
29. Crystal structures of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ
30. Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering
31. Protein modules as organizers of membrane structure
32. SAP90 binds and clusters kainate receptors causing incomplete desensitization
33. The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses
34. Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated protein
35. Syntenin, a PDZ protein that binds syndecan cytoplasmic domains
36. + exchange
37. G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interaction
38. CASK: A novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins
39. Anchoring proteins confer G protein sensitivity to an inward-rectifier K(+) channel through the GK domain
40. Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex
41. A novel multiple PDZ domain-containing molecule interacting with N-methyl-D-aspartate receptors and neuronal cell adhesion proteins
42. Disulfide-linked head-to-head multimerization in the mechanism of ion channel clustering by PSD-95
43. Regulated expression and subcellular localization of syndecan heparan sulfate proteoglycans and the syndecan-binding protein CASK/LIN-2 during rat brain development
44. Requirement of N-terminal cysteines of PSD-95 for PSD-95 multimerization and ternary complex formation, but not for binding to potassium channel Kv1.4
45. Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2
46. Direct interaction of CASK/LIN-2 and syndecan heparan sulfate proteoglycan and their overlapping distribution in neuronal synapses
47. Regulation of Neuregulin signaling by PSD-95 interacting with Erb4 at CNS synapses
48. + channel essential for phosphoinositide-mediated photoreception, forms a signaling complex with NorpA, InaC and InaD
49. Phosphorylation of the InaD gene product, a photoreceptor membrane protein required for recovery of visual excitation
50. Isolation and characterization of mammalian homologues of Caenorhabditis elegans lin-7: Localization at cell-cell junctions
51. Binding of neuroligins to PSD-95
52. Characterization of MALS/Velis-1, -2, and -3: A family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex
53. The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells
54. Molecular cloning and characterization of pals, proteins associated with mLin-7
55. The postsynaptic density at glutamatergic synapses
56. Heteromultimerization and NMDA receptor-clustering activity of chapsyn-110, a member of the PSD-95 family of proteins
57. Plasma membrane Ca2+ ATPase isoform 4b binds to membrane-associated guanylate kinase (MAGUK) proteins via their PDZ (PSD-95/Dlg/ZO-1) domains
58. GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules
59. + channels by interaction with a family of membrane-associated guanylate kinases
60. Organization and regulation of proteins at synapses
61. SynGAP: A synaptic RasGAP that associates with the PSD-95/SAP90 protein family
62. Polarized signaling: Basolateral receptor localization in epithelial cells by PDZ-containing proteins
63. SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A
64. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
65. Solution structure of the PDZ2 domain from human phosphatase hPTP1E and its interactions with C-terminal peptides from the fas receptor
66. Development of neuron-neuron synapses
67. SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit
68. AMPA receptor-PDZ interactions in facilitation of spinal sensory synapses
69. Src activation in the induction of long-term potentiation in CA1 hippocampal neurons
70. Two independent domains of hDlg are sufficient for subcellular targeting: The PDZ1-2 conformational unit and an alternatively spliced domain
71. Cloning and characterization of hdlg: The human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1
72. Modular organization of the PDZ domains in the human discs-large protein suggests a mechanism for coupling PDZ domain-binding proteins to ATP and the membrane cytoskeleton
73. The PDZ domain of human erythrocyte p55 mediates its binding to the cytoplasmic carboxyl terminus of glycophorin C. Analysis of the binding interface by in vitro mutagenesis
74. Phosphorylation of serine-880 in GluR2 by protein kinase C prevents its C terminus from binding with glutamate receptor-interacting protein
75. Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein
76. Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein
77. Assembly of signaling complexes by the sodium-hydrogen exchanger regulatory factor family of PDZ-containing proteins
78. Molecular architecture of tight junctions
79. TRP trapped in fly signaling web
80. Visual transduction in Drosophila
81. Crystal structure of a PDZ domain
82. Role of the carboxy-terminal region of the GluR epsilon2 subunit in synaptic localization of the NMDA receptor channel
83. SAP102, a novel postsynaptic protein that interacts with the cytoplasmic tail of the NMDA receptor subunit NR2B
84. Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin
85. Characterization of guanylate kinase-associated protein, a postsynaptic density protein at excitatory synapses that interacts directly with postysynaptic density-95/synapse-associated protein 90
86. Neuronal inwardly rectifying K(+) channels differentially couple to PDZ proteins of the PSD-95/SAP90 family
87. Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases
88. CRIPT, a novel postsynaptic protein that binds to the third PDZ domain of PSD-95/SAP90
89. Continual remodeling of postsynaptic density and its regulation by synaptic activity
90. Mints, munc 18-interacting proteins in synaptic vesicle exocytosis
91. Study of photoreceptor function using Drosophila mutants
92. Microtubule binding by CRIPT and its potential role in the synaptic clustering of PSD-95
93. PDZ-mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells
94. Selective acquisition of AMPA receptors over postnatal development suggests a molecular basis for silent synapses
95. Evidence for PDZ domains in bacteria, yeast, and plants
96. Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture
97. LIN-10 is a shared component of the polarized protein localization pathways in neurons and epithelia
98. FAP-1: A protein tyrosine phosphatase that associates with Fas
99. DAP-1, a novel protein that interacts with the guanylate kinase-like domains of hDLG and PSD-95
100. Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein
101. Specific interactions between the syntrophin PDZ domain and voltage-gated sodium channels
102. TRP, TRPL and trouble in photoreceptor cells
103. Assembly of the Drosophila phototransduction cascade into a signalling complex shapes elementary responses
104. Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins
105. The Shank family of scaffold proteins
106. Ligand-gated ion channel interactions with cytoskeletal and signaling proteins
107. A novel protein encoded by the InaD gene regulates recovery of visual transduction in Drosophila
108. Regulation of the TRP Ca2+ channel by INAD in drosophila photoreceptors
109. Association of INAD with NORPA is essential for controlled activation and deactivation of Drosophila phototransduction in vivo
110. LET-23 receptor localization by the cell junction protein LIN-7 during C. elegans vulval induction
111. Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapse
112. Recognition of unique carboxyl-terminal motifs by distinct PDZ domains
113. Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo
114. Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP
115. Specific interaction of the PDZ domain protein PICK1 with the COOH terminus of protein kinase C-alpha
116. PDZ domain of neuronal nitric oxide synthase recognizes novel C-terminal peptide sequences
117. SAPAPs a family of PSD-95/SAP90-associated proteins localized at postsynaptic density
118. + channels in vivo
119. PSD-95 promotes fynmediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A
120. Synaptic clustering of the cell adhesion molecule fasciclin II by discs-large and its role in the regulation of presynaptic structure
121. Solution structure and backbone dynamics of the second PDZ domain of postsynaptic density-95
122. Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide
123. + channel Kv1.4
124. PDZ proteins bind cluster and synaptically colocalize with Eph receptors and their ephrin ligands
125. A multivalent PDZ-domain protein assembles signalling complexes in a G- protein-coupled cascade
126. The organization of INAD-signaling complexes by a multivalent PDZ domain protein in Drosophila photoreceptor cells ensures sensitivity and speed of signaling
127. Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins
128. Cloning and characterization of MUPP1 a novel PDZ domain protein
129. Two distantly positioned PDZ domains mediate multivalent INAD-phospholipase C interactions essential for G protein-coupled signaling
130. Protein tyrosine phosphatases in the developing nervous system
131. Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)
132. Termination of phototransduction requires binding of the NINAC myosin III and the PDZ protein INAD
133. Basolateral localization of the Caenorhabditis elegans epidermal growth factor receptor in epithelial cells by the PDZ protein LIN-10
134. The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions
135. Subcellular targeting and cytoskeletal attachment of SAP97 to the epithelial lateral membrane
136. Biochemical and immunocytochemical characterization of GRIP a putative AMPA receptor anchoring protein in rat brain
137. Association of AMPA receptors with a subset of glutamate receptor-interacting protein in vivo
138. Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1
139. Coordination of an array of signaling proteins through homo- and heteromeric interactions between PDZ domains and target proteins
140. Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus
141. The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans
142. Enlightening the postsynaptic density
143. Synaptic clustering of fasciclin II and shaker: Essential targeting sequences and role of dlg