Impact of RNA-guided technologies for target identification and deconvolution

Journal of Biomolecular Screening

Volumn 19, Issue 10, 2014, Pages 1327-1337

  Fennell, Myles ^a   Xiang, Qing ^a   Hwang, Alexia ^a   Chen, Chong ^a   Huang, Chun Hao ^a   Chen, Chi Chao ^a   Pelossof, Raphael ^a   Garippa, Ralph J ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

CRISPR Cas9; deconvolution; functional genomics; HCS; OTE; pooled shRNA; review; RNAi; screening; viral vectors

Indexed keywords

GENOMIC DNA; MICRORNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; VIRUS VECTOR; DROSOPHILA PROTEIN; GUIDE RNA; PASHA PROTEIN, DROSOPHILA; RNA BINDING PROTEIN;

CRISPR CAS SYSTEM; EXPRESSION VECTOR; FUNCTIONAL GENOMICS; GENE SILENCING; GENE TECHNOLOGY; GENETIC SCREENING; GENETIC TRANSFECTION; GENOME; HUMAN; MOLECULAR LIBRARY; NONHUMAN; PROTEIN DENATURATION; REVIEW; RNA EDITING; RNA INTERFERENCE; ANIMAL; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENETICS; GENOMICS; HIGH THROUGHPUT SCREENING; MAMMAL; PROCEDURES;

ANIMALS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; DROSOPHILA PROTEINS; GENOMICS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MAMMALS; RNA INTERFERENCE; RNA, GUIDE; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS;

EID: 84912045430     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057114548414     Document Type: Review

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