Statistical methods for analysis of high-throughput RNA interference screens

Nature Methods

Volumn 6, Issue 8, 2009, Pages 569-575

  Birmingham, Amanda ^a,b   Selfors, Laura M ^a,c   Forster, Thorsten ^a,d   Wrobel, David ^a,c   Kennedy, Caleb J ^a,c   Shanks, Emma ^a,e   Santoyo Lopez, Javier ^a,d   Dunican, Dara J ^a,f   Long, Aideen ^a,f   Kelleher, Dermot ^a,f   Smith, Queta ^a,b   Beijersbergen, Roderick L ^a,g   Ghazal, Peter ^a,d   Shamu, Caroline E ^a,c  

^a The RNAi Global Initiative   (United States)

^b Thermo Fisher Scientific   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e UNIVERSITY OF DUNDEE   (United Kingdom)

^f TRINITY COLLEGE DUBLIN   (Ireland)

^g NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; RIBONUCLEASE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

BAYES THEOREM; DATA ANALYSIS; ENZYME KINETICS; GENETIC TRANSFECTION; HIGH THROUGHPUT SCREENING; MEDIAN ABSOLUTE DEVIATION; MULTIPLE T TEST; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; QUARTILE BASED; RANK PRODUCT; REDUNDANT SIRNA ACTIVITY; REVIEW; RNA INTERFERENCE; SSMD; STANDARD DEVIATION; STATISTICAL ANALYSIS;

ANIMALS; COMPUTER SIMULATION; MODELS, STATISTICAL; RESEARCH DESIGN; RNA INTERFERENCE; RNA, SMALL INTERFERING; SMALL MOLECULE LIBRARIES;

EID: 68349112682     PISSN: 15487091     EISSN: 15491676     Source Type: Journal    
DOI: 10.1038/nmeth.1351     Document Type: Review

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