Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor β signaling

Cell

Volumn 157, Issue 2, 2014, Pages 382-394

  Weissmueller, Susann ^a,b   Manchado, Eusebio ^b   Saborowski, Michael ^b   Morris IV, John P ^b   Wagenblast, Elvin ^a   Davis, Carrie A ^a   Moon, Sung Hwan ^c   Pfister, Neil T ^c   Tschaharganeh, Darjus F ^b   Kitzing, Thomas ^b   Aust, Daniela ^d   Markert, Elke K ^e   Wu, Jianmin ^f,g   Grimmond, Sean M ^h,i   Pilarsky, Christian ^d   Prives, Carol ^c   Biankin, Andrew V ^f,i   Lowe, Scott W ^a,b,j  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^e INSTITUTE FOR ADVANCED STUDY   (United States)

^f GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^g UNIVERSITY OF NEW SOUTH WALES   (Australia)

^h UNIVERSITY OF QUEENSLAND   (Australia)

ⁱ UNIVERSITY OF GLASGOW   (United Kingdom)

^j HOWARD HUGHES MEDICAL INSTITUTE   (United States)

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Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; NUCLEAR FACTOR Y; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN P53; PROTEIN P73; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER PATIENT; CELL INVASION; CHROMATIN IMMUNOPRECIPITATION; COLON CANCER; DISEASE FREE SURVIVAL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; METASTASIS; MISSENSE MUTATION; MOUSE; NONHUMAN; OVARY CANCER; PANCREAS CANCER; PHENOTYPE; PRIMARY TUMOR; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA SEQUENCE; STABLE EXPRESSION; TUMOR CELL; WESTERN BLOTTING; WOUND HEALING;

ANIMALS; CARCINOMA, PANCREATIC DUCTAL; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; HUMANS; MICE; NEOPLASM METASTASIS; PANCREATIC NEOPLASMS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84898614449     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.01.066     Document Type: Article

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