Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 12, 2014, Pages 4548-4553

  Franceschini, Andrea ^a   Meier, Roger ^b   Casanova, Alain ^c   Kreibich, Saskia ^b   Daga, Neha ^a   Andritschke, Daniel ^b   Dilling, Sabrina ^b   Ram̈ö, Pauli ^c   Emmenlauer, Mario ^c   Kaufmann, Andreas ^c   Conde Aĺvarez, Raquel ^c,d   Low, Shyan Huey ^c   Pelkmans, Lucas ^a   Helenius, Ari ^b   Hardt, Wolf Dietrich ^b   Dehio, Christoph ^c   Von Mering, Christian ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

^d UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Antimicrobials; High throughput RNAi screening

Indexed keywords

MESSENGER RNA; MICRORNA; SMALL INTERFERING RNA;

ARTICLE; BACTERIAL LOAD; CONTROLLED STUDY; FEMALE; GENETIC CODE; HELA CELL; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; PATHOGEN LOAD; PHENOTYPIC VARIATION; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RNA BINDING; RNA INTERFERENCE; RNA SEQUENCE; VIRUS LOAD;

ANTIMICROBIALS; HIGH-THROUGHPUT RNAI SCREENING;

BASE SEQUENCE; BRUCELLA ABORTUS; BUNYAVIRIDAE; GENES, BACTERIAL; HELA CELLS; HUMANS; MICRORNAS; OLIGONUCLEOTIDES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SALMONELLA TYPHIMURIUM;

EID: 84897002829     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1402353111     Document Type: Article

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