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Volumn 3, Issue 2, 2012, Pages 145-158

RNAi screening: New approaches, understandings, and organisms

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; SHORT HAIRPIN RNA;

EID: 84867594876     PISSN: 17577004     EISSN: 17577012     Source Type: Journal    
DOI: 10.1002/wrna.110     Document Type: Review
Times cited : (114)

References (156)
  • 1
    • 79751485564 scopus 로고    scopus 로고
    • The many faces of RNAi
    • Ketting RF. The many faces of RNAi. Dev cell 2011, 20:148-161.
    • (2011) Dev cell , vol.20 , pp. 148-161
    • Ketting, R.F.1
  • 2
    • 77953626646 scopus 로고    scopus 로고
    • Genomic screening with RNAi: results and challenges
    • Mohr S, Bakal C, Perrimon N. Genomic screening with RNAi: results and challenges. Ann Rev Biochem 2010, 79:37-64.
    • (2010) Ann Rev Biochem , vol.79 , pp. 37-64
    • Mohr, S.1    Bakal, C.2    Perrimon, N.3
  • 4
    • 45549089565 scopus 로고    scopus 로고
    • The art and design of genetic screens: RNA interference
    • Boutros M, Ahringer J. The art and design of genetic screens: RNA interference. Nature Rev Genet 2008, 9:554-566.
    • (2008) Nature Rev Genet , vol.9 , pp. 554-566
    • Boutros, M.1    Ahringer, J.2
  • 5
    • 79960338328 scopus 로고    scopus 로고
    • Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila
    • Neumuller RA, Perrimon N. Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila. Wiley Interdiscip Rev. Syst Biol Med 2010, 3:471-478.
    • (2010) Wiley Interdiscip Rev. Syst Biol Med , vol.3 , pp. 471-478
    • Neumuller, R.A.1    Perrimon, N.2
  • 6
    • 78649286116 scopus 로고    scopus 로고
    • RNAi screening for the discovery of novel modulators of human disease
    • Seyhan AA, Rya TE. RNAi screening for the discovery of novel modulators of human disease. Curr Pharma Biotechnol 2010, 11:735-756.
    • (2010) Curr Pharma Biotechnol , vol.11 , pp. 735-756
    • Seyhan, A.A.1    Rya, T.E.2
  • 7
    • 77950668281 scopus 로고    scopus 로고
    • High-throughput RNAi screening to dissect cellular pathways: a how-to guide
    • Falschlehner C, Steinbrink S, Erdmann G, Boutros M. High-throughput RNAi screening to dissect cellular pathways: a how-to guide. Biotechnol J 2010, 5:368-376.
    • (2010) Biotechnol J , vol.5 , pp. 368-376
    • Falschlehner, C.1    Steinbrink, S.2    Erdmann, G.3    Boutros, M.4
  • 8
    • 41649115887 scopus 로고    scopus 로고
    • Discovery of novel targets with high throughput RNA interference screening
    • Kassner PD. Discovery of novel targets with high throughput RNA interference screening. Combin Chem High Throughput Screen 2008, 11:175-184.
    • (2008) Combin Chem High Throughput Screen , vol.11 , pp. 175-184
    • Kassner, P.D.1
  • 9
    • 68049139405 scopus 로고    scopus 로고
    • What have RNAi screens taught us about viral-host interactions?
    • Cherry S. What have RNAi screens taught us about viral-host interactions? Curr Opin Microbiol 2009, 12:446-452.
    • (2009) Curr Opin Microbiol , vol.12 , pp. 446-452
    • Cherry, S.1
  • 10
    • 45849151106 scopus 로고    scopus 로고
    • Genomic RNAi screening in Drosophila S2 cells: what have we learned about host-pathogen interactions?
    • Cherry S. Genomic RNAi screening in Drosophila S2 cells: what have we learned about host-pathogen interactions? Curr Opin Microbiol 2008, 11:262-270.
    • (2008) Curr Opin Microbiol , vol.11 , pp. 262-270
    • Cherry, S.1
  • 11
    • 42149146685 scopus 로고    scopus 로고
    • From sequence to function: using RNAi to elucidate mechanisms of human disease
    • Wolters NM, MacKeigan JP. From sequence to function: using RNAi to elucidate mechanisms of human disease. Cell Death Different 2008, 15:809-819.
    • (2008) Cell Death Different , vol.15 , pp. 809-819
    • Wolters, N.M.1    MacKeigan, J.P.2
  • 12
    • 68049093863 scopus 로고    scopus 로고
    • Illuminating the host - how RNAi screens shed light on host-pathogen interactions
    • Prudencio M, Lehmann MJ. Illuminating the host - how RNAi screens shed light on host-pathogen interactions. Biotechnol J 2009, 4:826-837.
    • (2009) Biotechnol J , vol.4 , pp. 826-837
    • Prudencio, M.1    Lehmann, M.J.2
  • 13
    • 77950361791 scopus 로고    scopus 로고
    • RNAi screens to identify components of gene networks that modulate aging in Caenorhabditis elegans
    • Ni Z, Lee SS. RNAi screens to identify components of gene networks that modulate aging in Caenorhabditis elegans. Brief Funct Genom 2010, 9:53-64.
    • (2010) Brief Funct Genom , vol.9 , pp. 53-64
    • Ni, Z.1    Lee, S.S.2
  • 14
    • 79551632876 scopus 로고    scopus 로고
    • Protein kinase signaling networks in cancer
    • Brognard J, Hunter T. Protein kinase signaling networks in cancer. Curr Opin Genet Dev 2011, 21:4-11.
    • (2011) Curr Opin Genet Dev , vol.21 , pp. 4-11
    • Brognard, J.1    Hunter, T.2
  • 15
    • 78650290829 scopus 로고    scopus 로고
    • Using large-scale RNAi screens to identify novel drug targets for cancer
    • Nijwening JH, Beijersbergen RL. Using large-scale RNAi screens to identify novel drug targets for cancer. Drugs: Investig Drugs J 2010, 13:772-777.
    • (2010) Drugs: Investig Drugs J , vol.13 , pp. 772-777
    • Nijwening, J.H.1    Beijersbergen, R.L.2
  • 17
    • 77149130553 scopus 로고    scopus 로고
    • Automated microscopy for high-content RNAi screening
    • Conrad C, Gerlich DW. Automated microscopy for high-content RNAi screening. J Cell Biol 2010, 188:453-461.
    • (2010) J Cell Biol , vol.188 , pp. 453-461
    • Conrad, C.1    Gerlich, D.W.2
  • 19
    • 80051667741 scopus 로고    scopus 로고
    • RNAi pathways in parasitic protists and worms
    • Batista TM, Marques JT. RNAi pathways in parasitic protists and worms. J Proteom 2011, 74:1504-1514.
    • (2011) J Proteom , vol.74 , pp. 1504-1514
    • Batista, T.M.1    Marques, J.T.2
  • 20
    • 77951984913 scopus 로고    scopus 로고
    • RNAi for functional genomics in plants
    • McGinnis KM. RNAi for functional genomics in plants. Brief Funct Genom 2010, 9:111-117.
    • (2010) Brief Funct Genom , vol.9 , pp. 111-117
    • McGinnis, K.M.1
  • 22
    • 73449147408 scopus 로고    scopus 로고
    • Beyond Drosophila: RNAi in vivo and functional genomics in insects
    • Belles X. Beyond Drosophila: RNAi in vivo and functional genomics in insects. Ann Rev of Entomol 2010, 55:111-128.
    • (2010) Ann Rev of Entomol , vol.55 , pp. 111-128
    • Belles, X.1
  • 23
    • 79251469386 scopus 로고    scopus 로고
    • Vigilance and validation: keys to success in RNAi screening
    • Sigoillot FD, King RW. Vigilance and validation: keys to success in RNAi screening. ACS Chem Biol 2011, 6:47-60.
    • (2011) ACS Chem Biol , vol.6 , pp. 47-60
    • Sigoillot, F.D.1    King, R.W.2
  • 24
    • 79952589144 scopus 로고    scopus 로고
    • Promises and challenges in developing RNAi as a research tool and therapy
    • Sioud M. Promises and challenges in developing RNAi as a research tool and therapy. Methods Mol Biol 2011, 703:173-187.
    • (2011) Methods Mol Biol , vol.703 , pp. 173-187
    • Sioud, M.1
  • 26
    • 73349091855 scopus 로고    scopus 로고
    • Culture of Drosophila primary cells dissociated from gastrula embryos and their use in RNAi screening
    • Bai J, Sepp KJ, Perrimon N. Culture of Drosophila primary cells dissociated from gastrula embryos and their use in RNAi screening. Nat Protoc 2009, 4:1502-1512.
    • (2009) Nat Protoc , vol.4 , pp. 1502-1512
    • Bai, J.1    Sepp, K.J.2    Perrimon, N.3
  • 27
    • 44449117370 scopus 로고    scopus 로고
    • RNA interference screening in Drosophila primary cells for genes involved in muscle assembly and maintenance
    • Bai J, Binari R, Ni JQ, Vijayakanthan M, Li HS, Perrimon N. RNA interference screening in Drosophila primary cells for genes involved in muscle assembly and maintenance. Development 2008, 135:1439-1449.
    • (2008) Development , vol.135 , pp. 1439-1449
    • Bai, J.1    Binari, R.2    Ni, J.Q.3    Vijayakanthan, M.4    Li, H.S.5    Perrimon, N.6
  • 29
    • 79952022383 scopus 로고    scopus 로고
    • RNAi in stem cells: current status and future perspectives
    • Zou GM. RNAi in stem cells: current status and future perspectives. Methods Mol Biol 2010, 650:3-14.
    • (2010) Methods Mol Biol , vol.650 , pp. 3-14
    • Zou, G.M.1
  • 32
    • 77952489759 scopus 로고    scopus 로고
    • Pooled RNAi screens-technical and biological aspects
    • Boettcher M, Hoheisel JD. Pooled RNAi screens-technical and biological aspects. Curr Genom 2010, 11:162-167.
    • (2010) Curr Genom , vol.11 , pp. 162-167
    • Boettcher, M.1    Hoheisel, J.D.2
  • 33
    • 80355148655 scopus 로고    scopus 로고
    • MISSION esiRNA for RNAi screening in mammalian cells
    • Theis M, Buchholz F. MISSION esiRNA for RNAi screening in mammalian cells. J Visual Exper : JoVE 2010.
    • (2010) J Visual Exper : JoVE
    • Theis, M.1    Buchholz, F.2
  • 34
    • 79952693516 scopus 로고    scopus 로고
    • High-throughput RNAi screening in mammalian cells with esiRNAs
    • Theis M, Buchholz F. High-throughput RNAi screening in mammalian cells with esiRNAs. Methods 2011, 53:424-429.
    • (2011) Methods , vol.53 , pp. 424-429
    • Theis, M.1    Buchholz, F.2
  • 35
    • 78049437928 scopus 로고    scopus 로고
    • Design and evaluation of genome-wide libraries for RNA interference screens
    • Horn T, Sandmann T, Boutros M. Design and evaluation of genome-wide libraries for RNA interference screens. Genom Biol 2010, 11:R61.
    • (2010) Genom Biol , vol.11
    • Horn, T.1    Sandmann, T.2    Boutros, M.3
  • 38
  • 41
    • 79958003061 scopus 로고    scopus 로고
    • Large scale RNAi screen reveals that the Inhibitor of DNA binding 2 (ID2) protein is repressed by p53 family member p63 and functions in human keratinocyte differentiation
    • Wu N, Castel D, Debily MA, Vigano MA, Alibert O, Mantovani R, Iljin K, Romeo PH, Gidrol X. Large scale RNAi screen reveals that the Inhibitor of DNA binding 2 (ID2) protein is repressed by p53 family member p63 and functions in human keratinocyte differentiation. J Biol Chem 2011, 286:20870-20879.
    • (2011) J Biol Chem , vol.286 , pp. 20870-20879
    • Wu, N.1    Castel, D.2    Debily, M.A.3    Vigano, M.A.4    Alibert, O.5    Mantovani, R.6    Iljin, K.7    Romeo, P.H.8    Gidrol, X.9
  • 43
    • 79551595187 scopus 로고    scopus 로고
    • Miniaturization of biological assays-overview on microwell devices for single-cell analyses
    • 1810
    • Lindstrom S, Andersson-Svahn H. Miniaturization of biological assays-overview on microwell devices for single-cell analyses. Biochim Biophys Acta 2011, 1810:308-316.
    • (2011) Biochim Biophys Acta , pp. 308-316
    • Lindstrom, S.1    Andersson-Svahn, H.2
  • 44
    • 79953273231 scopus 로고    scopus 로고
    • Microfluidics-based devices: New tools for studying cancer and cancer stem cell migration
    • Huang Y, Agrawal B, Sun D, Kuo JS, Williams JC. Microfluidics-based devices: New tools for studying cancer and cancer stem cell migration. Biomicrofluidics 2011, 5:13412.
    • (2011) Biomicrofluidics , vol.5 , pp. 13412
    • Huang, Y.1    Agrawal, B.2    Sun, D.3    Kuo, J.S.4    Williams, J.C.5
  • 46
    • 79956077600 scopus 로고    scopus 로고
    • A genome-wide RNAi screen identifies novel targets of neratinib sensitivity leading to neratinib and paclitaxel combination drug treatments
    • Seyhan AA, Varadarajan U, Choe S, Liu Y, McGraw J, Woods M, Murray S, Eckert A, Liu W, Ryan TE. A genome-wide RNAi screen identifies novel targets of neratinib sensitivity leading to neratinib and paclitaxel combination drug treatments. Mol Biosyst 2011, 7:1974-1989.
    • (2011) Mol Biosyst , vol.7 , pp. 1974-1989
    • Seyhan, A.A.1    Varadarajan, U.2    Choe, S.3    Liu, Y.4    McGraw, J.5    Woods, M.6    Murray, S.7    Eckert, A.8    Liu, W.9    Ryan, T.E.10
  • 51
    • 77954851049 scopus 로고    scopus 로고
    • Wnt signaling regulates mitochondrial physiology and insulin sensitivity
    • Yoon JC, Ng A, Kim BH, Bianco A, Xavier RJ, Elledge SJ. Wnt signaling regulates mitochondrial physiology and insulin sensitivity. Genes Dev 2010, 24:1507-1518.
    • (2010) Genes Dev , vol.24 , pp. 1507-1518
    • Yoon, J.C.1    Ng, A.2    Kim, B.H.3    Bianco, A.4    Xavier, R.J.5    Elledge, S.J.6
  • 55
    • 77950525573 scopus 로고    scopus 로고
    • Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging
    • Walter T, Held M, Neumann B, Heriche JK, Conrad C, Pepperkok R, Ellenberg J. Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging. J Struct Biol 2010, 170:1-9.
    • (2010) J Struct Biol , vol.170 , pp. 1-9
    • Walter, T.1    Held, M.2    Neumann, B.3    Heriche, J.K.4    Conrad, C.5    Pepperkok, R.6    Ellenberg, J.7
  • 58
    • 79955612530 scopus 로고    scopus 로고
    • A parallel microfluidic flow cytometer for high-content screening
    • McKenna BK, Evans JG, Cheung MC, Ehrlich DJ. A parallel microfluidic flow cytometer for high-content screening. Nat Meth 2011, 8:401-403.
    • (2011) Nat Meth , vol.8 , pp. 401-403
    • McKenna, B.K.1    Evans, J.G.2    Cheung, M.C.3    Ehrlich, D.J.4
  • 60
    • 77951114378 scopus 로고    scopus 로고
    • Image analysis benchmarking methods for high-content screen design
    • Fuller CJ, Straight AF. Image analysis benchmarking methods for high-content screen design. J Microsc 2010, 238:145-161.
    • (2010) J Microsc , vol.238 , pp. 145-161
    • Fuller, C.J.1    Straight, A.F.2
  • 67
    • 34250882643 scopus 로고    scopus 로고
    • Quantitative morphological signatures define local signaling networks regulating cell morphology
    • Bakal C, Aach J, Church G, Perrimon N. Quantitative morphological signatures define local signaling networks regulating cell morphology. Science 2007, 316:1753-1756.
    • (2007) Science , vol.316 , pp. 1753-1756
    • Bakal, C.1    Aach, J.2    Church, G.3    Perrimon, N.4
  • 68
    • 47149116088 scopus 로고    scopus 로고
    • Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens
    • Yin Z, Zhou X, Bakal C, Li F, Sun Y, Perrimon N, Wong ST. Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens. BMC Bioinform 2008, 9:264.
    • (2008) BMC Bioinform , vol.9 , pp. 264
    • Yin, Z.1    Zhou, X.2    Bakal, C.3    Li, F.4    Sun, Y.5    Perrimon, N.6    Wong, S.T.7
  • 69
    • 77649259720 scopus 로고    scopus 로고
    • Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen
    • Nir O, Bakal C, Perrimon N, Berger B. Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen. Genome Res 2010, 20:372-380.
    • (2010) Genome Res , vol.20 , pp. 372-380
    • Nir, O.1    Bakal, C.2    Perrimon, N.3    Berger, B.4
  • 74
    • 77956283656 scopus 로고    scopus 로고
    • A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability
    • Hurov KE, Cotta-Ramusino C, Elledge SJ. A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability. Genes Dev 2010, 24:1939-1950.
    • (2010) Genes Dev , vol.24 , pp. 1939-1950
    • Hurov, K.E.1    Cotta-Ramusino, C.2    Elledge, S.J.3
  • 77
    • 34247278567 scopus 로고    scopus 로고
    • Combinatorial RNAi: a winning strategy for the race against evolving targets?
    • Grimm D, Kay MA. Combinatorial RNAi: a winning strategy for the race against evolving targets? Mol Therapy: J Am Soc Gene Therapy 2007, 15:878-888.
    • (2007) Mol Therapy: J Am Soc Gene Therapy , vol.15 , pp. 878-888
    • Grimm, D.1    Kay, M.A.2
  • 78
    • 34249041230 scopus 로고    scopus 로고
    • Exploring genetic interactions and networks with yeast
    • Boone C, Bussey H, Andrews BJ. Exploring genetic interactions and networks with yeast. Nat Rev Genet 2007, 8:437-449.
    • (2007) Nat Rev Genet , vol.8 , pp. 437-449
    • Boone, C.1    Bussey, H.2    Andrews, B.J.3
  • 79
    • 79953289737 scopus 로고    scopus 로고
    • Mapping of signaling networks through synthetic genetic interaction analysis by RNAi
    • Horn T, Sandmann T, Fischer B, Axelsson E, Huber W, Boutros M. Mapping of signaling networks through synthetic genetic interaction analysis by RNAi. Nat Meth 2011, 8:341-346.
    • (2011) Nat Meth , vol.8 , pp. 341-346
    • Horn, T.1    Sandmann, T.2    Fischer, B.3    Axelsson, E.4    Huber, W.5    Boutros, M.6
  • 81
    • 77954903711 scopus 로고    scopus 로고
    • Vectors and parameters that enhance the efficacy of RNAi-mediated gene disruption in transgenic Drosophila
    • Haley B, Foys B, Levine M. Vectors and parameters that enhance the efficacy of RNAi-mediated gene disruption in transgenic Drosophila. Proc Natl Acad Sci U S A 2010, 107:11435-11440.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 11435-11440
    • Haley, B.1    Foys, B.2    Levine, M.3
  • 82
    • 77957675719 scopus 로고    scopus 로고
    • A direct comparison of strategies for combinatorial RNA interference
    • Lambeth LS, Van Hateren NJ, Wilson SA, Nair V. A direct comparison of strategies for combinatorial RNA interference. BMC Mol Biol 2010, 11:77.
    • (2010) BMC Mol Biol , vol.11 , pp. 77
    • Lambeth, L.S.1    Van Hateren, N.J.2    Wilson, S.A.3    Nair, V.4
  • 84
    • 0033214763 scopus 로고    scopus 로고
    • Silencing of developmental genes in Hydra
    • Lohmann JU, Endl I, Bosch TC. Silencing of developmental genes in Hydra. Dev Biol 1999, 214:211-214.
    • (1999) Dev Biol , vol.214 , pp. 211-214
    • Lohmann, J.U.1    Endl, I.2    Bosch, T.C.3
  • 85
    • 17844395204 scopus 로고    scopus 로고
    • Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria
    • Reddien PW, Bermange AL, Murfitt KJ, Jennings JR, Sanchez Alvarado A. Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria. Dev Cell 2005, 8:635-649.
    • (2005) Dev Cell , vol.8 , pp. 635-649
    • Reddien, P.W.1    Bermange, A.L.2    Murfitt, K.J.3    Jennings, J.R.4    Sanchez Alvarado, A.5
  • 86
    • 77951991485 scopus 로고    scopus 로고
    • Reverse genetics techniques: engineering loss and gain of gene function in plants
    • Gilchrist E, Haughn G. Reverse genetics techniques: engineering loss and gain of gene function in plants. Brief Funct Genom 2010, 9:103-110.
    • (2010) Brief Funct Genom , vol.9 , pp. 103-110
    • Gilchrist, E.1    Haughn, G.2
  • 87
    • 78049436362 scopus 로고    scopus 로고
    • Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters
    • Schumann Burkard G, Jutzi P, Roditi I. Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters. Mol Biochem Parasitol 2011, 175:91-94.
    • (2011) Mol Biochem Parasitol , vol.175 , pp. 91-94
    • Schumann Burkard, G.1    Jutzi, P.2    Roditi, I.3
  • 88
    • 78951491179 scopus 로고    scopus 로고
    • Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6
    • Baker N, Alsford S, Horn D. Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6. Mol Biochem Parasitol 2011, 176:55-57.
    • (2011) Mol Biochem Parasitol , vol.176 , pp. 55-57
    • Baker, N.1    Alsford, S.2    Horn, D.3
  • 89
    • 70350247605 scopus 로고    scopus 로고
    • RNAi and functional genomics in plant parasitic nematodes
    • Rosso MN, Jones JT, Abad P. RNAi and functional genomics in plant parasitic nematodes. Ann Rev Phytopathol 2009, 47:207-232.
    • (2009) Ann Rev Phytopathol , vol.47 , pp. 207-232
    • Rosso, M.N.1    Jones, J.T.2    Abad, P.3
  • 90
    • 80955137636 scopus 로고    scopus 로고
    • Biotechnological application of functional genomics towards plant-parasitic nematode control
    • doi:10.1111/j 1467-7652.2011.00601.x. [Epub ahead of print].
    • Li J, Todd TC, Lee J, Trick HN. Biotechnological application of functional genomics towards plant-parasitic nematode control. Plant Biotechnol J 2011. doi:10.1111/j 1467-7652.2011.00601.x. [Epub ahead of print].
    • (2011) Plant Biotechnol J
    • Li, J.1    Todd, T.C.2    Lee, J.3    Trick, H.N.4
  • 93
    • 79954516469 scopus 로고    scopus 로고
    • Second-generation sequencing supply an effective way to screen RNAi targets in large scale for potential application in pest insect control
    • Wang Y, Zhang H, Li H, Miao X. Second-generation sequencing supply an effective way to screen RNAi targets in large scale for potential application in pest insect control. PloS One 2011, 6:e18644.
    • (2011) PloS One , vol.6
    • Wang, Y.1    Zhang, H.2    Li, H.3    Miao, X.4
  • 94
    • 45049083618 scopus 로고    scopus 로고
    • RNAi-mediated crop protection against insects
    • Price DR, Gatehouse JA. RNAi-mediated crop protection against insects. Trend Biotechnol 2008, 26:393-400.
    • (2008) Trend Biotechnol , vol.26 , pp. 393-400
    • Price, D.R.1    Gatehouse, J.A.2
  • 95
    • 70349798565 scopus 로고    scopus 로고
    • Crop improvement using small RNAs: applications and predictive ecological risk assessments
    • Auer C, Frederick R. Crop improvement using small RNAs: applications and predictive ecological risk assessments. Trend Biotechnol 2009, 27:644-651.
    • (2009) Trend Biotechnol , vol.27 , pp. 644-651
    • Auer, C.1    Frederick, R.2
  • 96
    • 79952795523 scopus 로고    scopus 로고
    • RNA interference of four genes in adult bactrocera dorsalis by feeding their dsRNAs
    • Li X, Zhang M, Zhang H. RNA interference of four genes in adult bactrocera dorsalis by feeding their dsRNAs. PloS One 2011, 6:e17788.
    • (2011) PloS One , vol.6
    • Li, X.1    Zhang, M.2    Zhang, H.3
  • 97
    • 75749151616 scopus 로고    scopus 로고
    • Mechanisms of dsRNA uptake in insects and potential of RNAi for pest control: a review
    • Huvenne H, Smagghe G. Mechanisms of dsRNA uptake in insects and potential of RNAi for pest control: a review. J Insect Physiol 2010, 56:227-235.
    • (2010) J Insect Physiol , vol.56 , pp. 227-235
    • Huvenne, H.1    Smagghe, G.2
  • 98
    • 78049312236 scopus 로고    scopus 로고
    • RNA interference in ageing research-a mini-review
    • Minois N, Sykacek P, Godsey B, Kreil DP. RNA interference in ageing research-a mini-review. Gerontology 2010, 56:496-506.
    • (2010) Gerontology , vol.56 , pp. 496-506
    • Minois, N.1    Sykacek, P.2    Godsey, B.3    Kreil, D.P.4
  • 99
    • 79551553753 scopus 로고    scopus 로고
    • RNAi screening for fat regulatory genes with SRS microscopy
    • Wang MC, Min W, Freudiger CW, Ruvkun G, Xie XS. RNAi screening for fat regulatory genes with SRS microscopy. Nat Meth 2011, 8:135-138.
    • (2011) Nat Meth , vol.8 , pp. 135-138
    • Wang, M.C.1    Min, W.2    Freudiger, C.W.3    Ruvkun, G.4    Xie, X.S.5
  • 101
    • 78651329567 scopus 로고    scopus 로고
    • Some highlights of research on aging with invertebrates, 2010
    • Partridge L. Some highlights of research on aging with invertebrates, 2010. Aging Cell 2011, 10:5-9.
    • (2011) Aging Cell , vol.10 , pp. 5-9
    • Partridge, L.1
  • 102
    • 79953228554 scopus 로고    scopus 로고
    • Reliability analysis of the Ahringer Caenorhabditis elegans RNAi feeding library: a guide for genome-wide screens
    • Qu W, Ren C, Li Y, Shi J, Zhang J, Wang X, Hang X, Lu Y, Zhao D, Zhang C. Reliability analysis of the Ahringer Caenorhabditis elegans RNAi feeding library: a guide for genome-wide screens. BMC Genom 2011, 12:170.
    • (2011) BMC Genom , vol.12 , pp. 170
    • Qu, W.1    Ren, C.2    Li, Y.3    Shi, J.4    Zhang, J.5    Wang, X.6    Hang, X.7    Lu, Y.8    Zhao, D.9    Zhang, C.10
  • 105
    • 79959812501 scopus 로고    scopus 로고
    • A genome-wide RNAi screen for factors involved in neuronal specification in Caenorhabditis elegans
    • Poole RJ, Bashllari E, Cochella L, Flowers EB, Hobert O. A genome-wide RNAi screen for factors involved in neuronal specification in Caenorhabditis elegans. PLoS Genet 2011, 7:e1002109.
    • (2011) PLoS Genet , vol.7
    • Poole, R.J.1    Bashllari, E.2    Cochella, L.3    Flowers, E.B.4    Hobert, O.5
  • 107
    • 0037373298 scopus 로고    scopus 로고
    • Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila
    • Roignant JY, Carre C, Mugat B, Szymczak D, Lepesant JA, Antoniewski C. Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila. RNA 2003, 9:299-308.
    • (2003) RNA , vol.9 , pp. 299-308
    • Roignant, J.Y.1    Carre, C.2    Mugat, B.3    Szymczak, D.4    Lepesant, J.A.5    Antoniewski, C.6
  • 113
    • 79955106109 scopus 로고    scopus 로고
    • Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila
    • Fernandes C, Rao Y. Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila. Mol Brain 2011, 4:17.
    • (2011) Mol Brain , vol.4 , pp. 17
    • Fernandes, C.1    Rao, Y.2
  • 116
    • 70349536006 scopus 로고    scopus 로고
    • In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression
    • Meacham CE, Ho EE, Dubrovsky E, Gertler FB, Hemann MT. In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. Nat Genet 2009, 41:1133-1137.
    • (2009) Nat Genet , vol.41 , pp. 1133-1137
    • Meacham, C.E.1    Ho, E.E.2    Dubrovsky, E.3    Gertler, F.B.4    Hemann, M.T.5
  • 120
    • 77954534273 scopus 로고    scopus 로고
    • Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos
    • Beronja S, Livshits G, Williams S, Fuchs E. Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos. Nat Med 2010, 16:821-827.
    • (2010) Nat Med , vol.16 , pp. 821-827
    • Beronja, S.1    Livshits, G.2    Williams, S.3    Fuchs, E.4
  • 121
    • 79951784680 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote Notch-dependent epidermal differentiation
    • Williams SE, Beronja S, Pasolli HA, Fuchs E. Asymmetric cell divisions promote Notch-dependent epidermal differentiation. Nature 2011, 470:353-358.
    • (2011) Nature , vol.470 , pp. 353-358
    • Williams, S.E.1    Beronja, S.2    Pasolli, H.A.3    Fuchs, E.4
  • 123
    • 52949087943 scopus 로고    scopus 로고
    • Identification of JAK/STAT pathway regulators-insights from RNAi screens
    • Muller P, Boutros M, Zeidler MP. Identification of JAK/STAT pathway regulators-insights from RNAi screens. Semin Cell Dev Biol 2008, 19:360-369.
    • (2008) Semin Cell Dev Biol , vol.19 , pp. 360-369
    • Muller, P.1    Boutros, M.2    Zeidler, M.P.3
  • 125
    • 33646187810 scopus 로고    scopus 로고
    • High-throughput RNAi screening in cultured cells: a user's guide
    • Echeverri CJ, Perrimon N. High-throughput RNAi screening in cultured cells: a user's guide. Nature Rev Genet 2006, 7:373-384.
    • (2006) Nature Rev Genet , vol.7 , pp. 373-384
    • Echeverri, C.J.1    Perrimon, N.2
  • 127
    • 79953236944 scopus 로고    scopus 로고
    • Disturbance of the microRNA pathway by commonly used lentiviral shRNA libraries limits the application for screening host factors involved in hepatitis C virus infection
    • Pan Q, de Ruiter PE, von Eije KJ, Smits R, Kwekkeboom J, Tilanus HW, Berkhout B, Janssen HL, van der Laan LJ. Disturbance of the microRNA pathway by commonly used lentiviral shRNA libraries limits the application for screening host factors involved in hepatitis C virus infection. FEBS Lett 2011, 585:1025-1030.
    • (2011) FEBS Lett , vol.585 , pp. 1025-1030
    • Pan, Q.1    de Ruiter, P.E.2    von Eije, K.J.3    Smits, R.4    Kwekkeboom, J.5    Tilanus, H.W.6    Berkhout, B.7    Janssen, H.L.8    van der Laan, L.J.9
  • 130
    • 80051872191 scopus 로고    scopus 로고
    • RNAi-induced off-target effects in Drosophila melanogaster: frequencies and solutions
    • Seinen E, Burgerhof JG, Jansen RC, Sibon OC. RNAi-induced off-target effects in Drosophila melanogaster: frequencies and solutions. Brief Funct Genom 2011, 10:206-214.
    • (2011) Brief Funct Genom , vol.10 , pp. 206-214
    • Seinen, E.1    Burgerhof, J.G.2    Jansen, R.C.3    Sibon, O.C.4
  • 131
    • 78049294739 scopus 로고    scopus 로고
    • RNAi experiments in D. melanogaster: solutions to the overlooked problem of off-targets shared by independent dsRNAs.
    • Seinen E, Burgerhof JG, Jansen RC, Sibon OC. RNAi experiments in D. melanogaster: solutions to the overlooked problem of off-targets shared by independent dsRNAs. PloS One 2010, 5:e13119.
    • (2010) PloS One , vol.5
    • Seinen, E.1    Burgerhof, J.G.2    Jansen, R.C.3    Sibon, O.C.4
  • 134
    • 38449084517 scopus 로고    scopus 로고
    • Design and implementation of high-throughput RNAi screens in cultured Drosophila cells
    • Ramadan N, Flockhart I, Booker M, Perrimon N, Mathey-Prevot B. Design and implementation of high-throughput RNAi screens in cultured Drosophila cells. Nature Protocols 2007, 2:2245-2264.
    • (2007) Nature Protocols , vol.2 , pp. 2245-2264
    • Ramadan, N.1    Flockhart, I.2    Booker, M.3    Perrimon, N.4    Mathey-Prevot, B.5
  • 136
    • 78650142748 scopus 로고    scopus 로고
    • An effective method for controlling false discovery and false nondiscovery rates in genome-scale RNAi screens
    • Zhang XD. An effective method for controlling false discovery and false nondiscovery rates in genome-scale RNAi screens. J Biomol Screen: Off J Soc Biomol Screen 2010, 15:1116-1122.
    • (2010) J Biomol Screen: Off J Soc Biomol Screen , vol.15 , pp. 1116-1122
    • Zhang, X.D.1
  • 138
    • 67649601037 scopus 로고    scopus 로고
    • RNAiCut: automated detection of significant genes from functional genomic screens
    • Kaplow IM, Singh R, Friedman A, Bakal C, Perrimon N, Berger B. RNAiCut: automated detection of significant genes from functional genomic screens. Nat Meth 2009, 6:476-477.
    • (2009) Nat Meth , vol.6 , pp. 476-477
    • Kaplow, I.M.1    Singh, R.2    Friedman, A.3    Bakal, C.4    Perrimon, N.5    Berger, B.6
  • 139
    • 70349439132 scopus 로고    scopus 로고
    • Generating 'omic knowledge': the role of informatics in high content screening
    • Collins MA. Generating 'omic knowledge': the role of informatics in high content screening. Combin Chem High Throughput Screen 2009, 12:917-925.
    • (2009) Combin Chem High Throughput Screen , vol.12 , pp. 917-925
    • Collins, M.A.1
  • 142
    • 72449143602 scopus 로고    scopus 로고
    • Cross-species RNAi rescue platform in Drosophila melanogaster
    • Kondo S, Booker M, Perrimon N. Cross-species RNAi rescue platform in Drosophila melanogaster. Genetics 2009, 183:1165-1173.
    • (2009) Genetics , vol.183 , pp. 1165-1173
    • Kondo, S.1    Booker, M.2    Perrimon, N.3
  • 143
    • 67949104969 scopus 로고    scopus 로고
    • A novel method for tissue-specific RNAi rescue in Drosophila
    • Schulz JG, David G, Hassan BA. A novel method for tissue-specific RNAi rescue in Drosophila. Nucleic Acids Res 2009, 37:e93.
    • (2009) Nucleic Acids Res , vol.37
    • Schulz, J.G.1    David, G.2    Hassan, B.A.3
  • 144
    • 77749245950 scopus 로고    scopus 로고
    • In vivo RNAi rescue in Drosophila melanogaster with genomic transgenes from Drosophila pseudoobscura
    • Langer CC, Ejsmont RK, Schonbauer C, Schnorrer F, Tomancak P. In vivo RNAi rescue in Drosophila melanogaster with genomic transgenes from Drosophila pseudoobscura. PloS One 2010, 5:e8928.
    • (2010) PloS One , vol.5
    • Langer, C.C.1    Ejsmont, R.K.2    Schonbauer, C.3    Schnorrer, F.4    Tomancak, P.5
  • 146
    • 40849150778 scopus 로고    scopus 로고
    • Identification of SUMO-dependent chromatin-associated transcriptional repression components by a genome-wide RNAi screen
    • Stielow B, Sapetschnig A, Kruger I, Kunert N, Brehm A, Boutros M, Suske G. Identification of SUMO-dependent chromatin-associated transcriptional repression components by a genome-wide RNAi screen. Mol Cell 2008, 29:742-754.
    • (2008) Mol Cell , vol.29 , pp. 742-754
    • Stielow, B.1    Sapetschnig, A.2    Kruger, I.3    Kunert, N.4    Brehm, A.5    Boutros, M.6    Suske, G.7
  • 148
    • 23944443257 scopus 로고    scopus 로고
    • The best control for the specificity of RNAi
    • Sarov M, Stewart AF. The best control for the specificity of RNAi. Trend Biotechnol 2005, 23:446-448.
    • (2005) Trend Biotechnol , vol.23 , pp. 446-448
    • Sarov, M.1    Stewart, A.F.2
  • 151
    • 84867595399 scopus 로고    scopus 로고
    • Note
    • BioMed Central RNAi Gateway,
  • 152
    • 79954580272 scopus 로고    scopus 로고
    • Davidson BL, McCray PB Jr. Current prospects for RNA interference-based therapies. Nat Rev Genet
    • Davidson BL, McCray PB Jr. Current prospects for RNA interference-based therapies. Nat Rev Genet 2011, 12:329-340.
    • (2011) , vol.12 , pp. 329-340
  • 153
    • 84867613514 scopus 로고    scopus 로고
    • Howard Hughes Medical Institute Biointeractive, RNA Interference: New Twist in the RNA World
    • Howard Hughes Medical Institute Biointeractive, RNA Interference: New Twist in the RNA World,
  • 154
    • 84867594908 scopus 로고    scopus 로고
    • July 2005 NOVA Program on RNAi
    • July 2005 NOVA Program on RNAi,
    • (2005)
  • 155
    • 84867613516 scopus 로고    scopus 로고
    • Nature Reviews RNAi Collection
    • Nature Reviews RNAi Collection,
  • 156
    • 84867594907 scopus 로고    scopus 로고
    • Note
    • Nikon MicroscopyU Online Review Article, The Automatic Microscope.


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