-
1
-
-
0031695197
-
Projections of alzheimer’s disease in the united states and the public health impact of delaying disease onset
-
Brookmeyer R, Gray S, Kawas C. Projections of Alzheimer’s disease in the United States and the public health impact of delaying disease onset. Am J Public Health, 1998; 88:1337-1342.
-
(1998)
Am J Public Health
, vol.88
, pp. 1337-1342
-
-
Brookmeyer, R.1
Gray, S.2
Kawas, C.3
-
2
-
-
0000858424
-
Uber einen eigenartigen schweren krankheitsprozess der hirnrinde
-
Alzheimer A. Uber einen eigenartigen schweren Krankheitsprozess der Hirnrinde. Zentralbl Nervenkrankheiten, 1906; 25:1134.
-
(1906)
Zentralbl Nervenkrankheiten
, vol.25
, pp. 1134
-
-
Alzheimer, A.1
-
3
-
-
8344235899
-
Therapeutic potential of oxidant mechanisms in alzheimer disease
-
Moreira PI, Smith MA, Zhu X, Santos MS, Oliveira CR, Perry G. Therapeutic potential of oxidant mechanisms in Alzheimer disease. Expert Rev Neurotherapeutics, 2004; 4:995-1004.
-
(2004)
Expert Rev Neurotherapeutics
, vol.4
, pp. 995-1004
-
-
Moreira, P.I.1
Smith, M.A.2
Zhu, X.3
Santos, M.S.4
Oliveira, C.R.5
Perry, G.6
-
4
-
-
13644249113
-
Chronological primacy of oxidative stress in alzheimer disease
-
discussion 587-595
-
Smith MA, Nunomura A, Lee HG, Zhu X, Moreira PI, Avila J, Perry G. Chronological primacy of oxidative stress in Alzheimer disease. Neurobiol Aging, 2005; 26:579-580; discussion 587-595.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 579-580
-
-
Smith, M.A.1
Nunomura, A.2
Lee, H.G.3
Zhu, X.4
Moreira, P.I.5
Avila, J.6
Perry, G.7
-
5
-
-
0024790459
-
Protection against tissue damage in vivo by desferrioxamine: What is its mechanism of action?
-
Halliwell B. Protection against tissue damage in vivo by desferrioxamine: what is its mechanism of action? Free Radic Biol Med, 1989; 7:645-651.
-
(1989)
Free Radic Biol Med
, vol.7
, pp. 645-651
-
-
Halliwell, B.1
-
6
-
-
0032749848
-
Mitochondrial physiology and pathology; concepts of programmed death of organelles, cells and organisms
-
Skulachev VP. Mitochondrial physiology and pathology; concepts of programmed death of organelles, cells and organisms. Mol Aspects Med, 1999; 20:139-184.
-
(1999)
Mol Aspects Med
, vol.20
, pp. 139-184
-
-
Skulachev, V.P.1
-
7
-
-
18744374615
-
Is oxidative damage the fundamental pathogenic mechanism of alzheimer’s and other neurodegenerative diseases?
-
Perry G, Nunomura A, Hirai K, Zhu X, Perez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer’s and other neurodegenerative diseases? Free Radic Biol Med, 2002; 33:1475-1479.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 1475-1479
-
-
Perry, G.1
Nunomura, A.2
Hirai, K.3
Zhu, X.4
Perez, M.5
Avila, J.6
Castellani, R.J.7
Atwood, C.S.8
Aliev, G.9
Sayre, L.M.10
Takeda, A.11
Smith, M.A.12
-
8
-
-
0024204731
-
The glucose transporter of the human brain and blood-brain barrier
-
Kalaria RN, Gravina SA, Schmidley JW, Perry G, Harik SI. The glucose transporter of the human brain and blood-brain barrier. Ann Neurol, 1988; 24:757-764.
-
(1988)
Ann Neurol
, vol.24
, pp. 757-764
-
-
Kalaria, R.N.1
Gravina, S.A.2
Schmidley, J.W.3
Perry, G.4
Harik, S.I.5
-
9
-
-
0035341254
-
Mitochondrial abnormalities in alzheimer’s disease
-
Hirai K, Aliev G, Nunomura A, Fujioka H, Russell RL, Atwood CS, Johnson AB, Kress Y, Vinters HV, Tabaton M, Shimohama S, Cash AD, Siedlak SL, Harris PL, Jones PK, Petersen RB, Perry G, Smith MA. Mitochondrial abnormalities in Alzheimer’s disease. J Neurosci, 2001; 21:3017-3023.
-
(2001)
J Neurosci
, vol.21
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
Fujioka, H.4
Russell, R.L.5
Atwood, C.S.6
Johnson, A.B.7
Kress, Y.8
Vinters, H.V.9
Tabaton, M.10
Shimohama, S.11
Cash, A.D.12
Siedlak, S.L.13
Harris, P.L.14
Jones, P.K.15
Petersen, R.B.16
Perry, G.17
Smith, M.A.18
-
10
-
-
0033525773
-
Mitochondrial diseases in man and mouse
-
Wallace DC. Mitochondrial diseases in man and mouse. Science, 1999; 283:1482-1488.
-
(1999)
Science
, vol.283
, pp. 1482-1488
-
-
Wallace, D.C.1
-
11
-
-
0030885482
-
Iron accumulation in alzheimer disease is a source of redox-generated free radicals
-
Smith MA, Harris PL, Sayre LM, Perry G. Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc Natl Acad Sci USA, 1997; 94:9866-9868.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9866-9868
-
-
Smith, M.A.1
Harris, P.L.2
Sayre, L.M.3
Perry, G.4
-
12
-
-
20444383489
-
Ribosomal rna in alzheimer disease is oxidized by bound redox-active iron
-
Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, Perry G. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem, 2005; 280: 20978-20986.
-
(2005)
J Biol Chem
, vol.280
, pp. 20978-20986
-
-
Honda, K.1
Smith, M.A.2
Zhu, X.3
Baus, D.4
Merrick, W.C.5
Tartakoff, A.M.6
Hattier, T.7
Harris, P.L.8
Siedlak, S.L.9
Fujioka, H.10
Liu, Q.11
Moreira, P.I.12
Miller, F.P.13
Nunomura, A.14
Shimohama, S.15
Perry, G.16
-
13
-
-
1842453324
-
Oxidative stress signalling in alzheimer’s disease
-
Zhu X, Raina AK, Lee HG, Casadesus G, Smith MA, Perry G. Oxidative stress signalling in Alzheimer’s disease. Brain Res, 2004; 1000: 32-39.
-
(2004)
Brain Res
, vol.1000
, pp. 32-39
-
-
Zhu, X.1
Raina, A.K.2
Lee, H.G.3
Casadesus, G.4
Smith, M.A.5
Perry, G.6
-
14
-
-
0037010312
-
Role of mitochondrial dysfunction in alzheimer’s disease
-
Castellani R, Hirai K, Aliev G, Drew KL, Nunomura A, Takeda A, Cash AD, Obrenovich ME, Perry G, Smith MA. Role of mitochondrial dysfunction in Alzheimer’s disease. J Neurosci Res, 2002; 70: 357-360.
-
(2002)
J Neurosci Res
, vol.70
, pp. 357-360
-
-
Castellani, R.1
Hirai, K.2
Aliev, G.3
Drew, K.L.4
Nunomura, A.5
Takeda, A.6
Cash, A.D.7
Obrenovich, M.E.8
Perry, G.9
Smith, M.A.10
-
15
-
-
0242600546
-
Microtubule reduction in alzheimer’s disease and aging is independent of tau filament formation
-
Cash AD, Aliev G, Siedlak SL, Nunomura A, Fujioka H, Zhu X, Raina AK, Vinters HV, Tabaton M, Johnson AB, Paula-Barbosa M, Avila J, Jones PK, Castellani RJ, Smith MA, Perry G. Microtubule reduction in Alzheimer’s disease and aging is independent of tau filament formation. Am J Pathol, 2003; 162:1623-1627.
-
(2003)
Am J Pathol
, vol.162
, pp. 1623-1627
-
-
Cash, A.D.1
Aliev, G.2
Siedlak, S.L.3
Nunomura, A.4
Fujioka, H.5
Zhu, X.6
Raina, A.K.7
Vinters, H.V.8
Tabaton, M.9
Johnson, A.B.10
Paula-Barbosa, M.11
Avila, J.12
Jones, P.K.13
Castellani, R.J.14
Smith, M.A.15
Perry, G.16
-
16
-
-
0028304705
-
Heme oxygenase-1 is associated with the neurofibrillary pathology of alzheimer’s disease
-
Smith MA, Kutty RK, Richey PL, Yan SD, Stern D, Chader GJ, Wiggert B, Petersen RB, Perry G. Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer’s disease. Am J Pathol, 1994; 145:42-47.
-
(1994)
Am J Pathol
, vol.145
, pp. 42-47
-
-
Smith, M.A.1
Kutty, R.K.2
Richey, P.L.3
Yan, S.D.4
Stern, D.5
Chader, G.J.6
Wiggert, B.7
Petersen, R.B.8
Perry, G.9
-
17
-
-
0029157442
-
Induction of heme oxygenase-1 mrna and protein in neocortex and cerebral vessels in alzheimer’s disease
-
Premkumar DR, Smith MA, Richey PL, Petersen RB, Castellani R, Kutty RK, Wiggert B, Perry G, Kalaria RN. Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer’s disease. J Neurochem, 1995; 65:1399-1402.
-
(1995)
J Neurochem
, vol.65
, pp. 1399-1402
-
-
Premkumar, D.R.1
Smith, M.A.2
Richey, P.L.3
Petersen, R.B.4
Castellani, R.5
Kutty, R.K.6
Wiggert, B.7
Perry, G.8
Kalaria, R.N.9
-
18
-
-
0024497521
-
Heme oxygenase is the major 32-kda stress protein induced in human skin fibroblasts by uva radiation, hydrogen peroxide, and sodium arsenite
-
Keyse SM, Tyrrell RM. Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Proc Natl Acad Sci USA, 1989; 86:99-103.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 99-103
-
-
Keyse, S.M.1
Tyrrell, R.M.2
-
19
-
-
1842608804
-
Oxidative stress and redox-active iron in alzheimer’s disease
-
Honda K, Casadesus G, Petersen RB, Perry G, Smith MA. Oxidative stress and redox-active iron in Alzheimer’s disease. Ann NY Acad Sci, 2004; 1012:179-182.
-
(2004)
Ann NY Acad Sci
, vol.1012
, pp. 179-182
-
-
Honda, K.1
Casadesus, G.2
Petersen, R.B.3
Perry, G.4
Smith, M.A.5
-
20
-
-
0033559462
-
Rna oxidation is a prominent feature of vulnerable neurons in alzheimer’s disease
-
Nunomura A, Perry G, Pappolla MA, Wade R, Hirai K, Chiba S, Smith MA. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer’s disease. J Neurosci, 1999; 19: 1959-1964.
-
(1999)
J Neurosci
, vol.19
, pp. 1959-1964
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
Wade, R.4
Hirai, K.5
Chiba, S.6
Smith, M.A.7
-
21
-
-
0033954991
-
Oxidative stress and alzheimer disease
-
Christen Y. Oxidative stress and Alzheimer disease. Am J Clin Nutr, 2000; 71:621S-629S.
-
(2000)
Am J Clin Nutr
, vol.71
, pp. 621S-629S
-
-
Christen, Y.1
-
22
-
-
0029909010
-
Neuroprotection by the metabolic antioxidant alpha-lipoic acid
-
Packer L, Tritschler HJ, Wessel K. Neuroprotection by the metabolic antioxidant alpha-lipoic acid. Free Radic Biol Med, 1997; 22:359-378.
-
(1997)
Free Radic Biol Med
, vol.22
, pp. 359-378
-
-
Packer, L.1
Tritschler, H.J.2
Wessel, K.3
-
23
-
-
0033042929
-
Bartholomew jc, ames ab. (r)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate. faseb
-
Hagen TM, Ingersoll RT, Lykkesfeldt J, Liu J, Wehr CM, Vinarsky V, Bartholomew JC, Ames AB. (R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate. FASEB J, 1999; 13:411-418.
-
(1999)
FASEB J
, vol.13
, pp. 411-418
-
-
Hagen, T.M.1
Ingersoll, R.T.2
Lykkesfeldt, J.3
Liu, J.4
Wehr, C.M.5
Vinarsky, V.6
-
24
-
-
1042290476
-
(R)-alpha-lipoic acid reverses the age-related loss in gsh redox status in post-mitotic tissues: Evidence for increased cysteine requirement for gsh synthesis
-
Suh JH, Wang H, Liu RM, Liu J, Hagen TM. (R)-alpha-lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis. Arch Biochem Biophys, 2004; 423:126-135.
-
(2004)
Arch Biochem Biophys
, vol.423
, pp. 126-135
-
-
Suh, J.H.1
Wang, H.2
Liu, R.M.3
Liu, J.4
Hagen, T.M.5
-
25
-
-
0034986275
-
Alpha-lipoic acid as a new treatment option for azheimer type dementia
-
Hager K, Marahrens A, Kenklies M, Riederer P, Munch G. Alpha-lipoic acid as a new treatment option for Azheimer type dementia. Arch Gerontol Geriatr, 2001; 32:275-282.
-
(2001)
Arch Gerontol Geriatr
, vol.32
, pp. 275-282
-
-
Hager, K.1
Marahrens, A.2
Kenklies, M.3
Riederer, P.4
Munch, G.5
-
26
-
-
12144290583
-
(R)-, but not (s)-alpha lipoic acid stimulates deficient brain pyruvate dehydrogenase complex in vascular dementia, but not in alzheimer dementia
-
Frolich L, Gotz ME, Weinmuller M, Youdim MB, Barth N, Dirr A, Gsell W, Jellinger K, Beckmann H, Riederer P. (r)-, but not (s)-alpha lipoic acid stimulates deficient brain pyruvate dehydrogenase complex in vascular dementia, but not in Alzheimer dementia. J Neural Transm, 2004; 111: 295-310.
-
(2004)
J Neural Transm
, vol.111
, pp. 295-310
-
-
Frolich, L.1
Gotz, M.E.2
Weinmuller, M.3
Youdim, M.B.4
Barth, N.5
Dirr, A.6
Gsell, W.7
Jellinger, K.8
Beckmann, H.9
Riederer, P.10
-
27
-
-
0142010609
-
Protection against amyloid beta peptide and iron/hydrogen peroxide toxicity by alpha lipoic acid
-
Lovell MA, Xie C, Xiong S, Markesbery WR. Protection against amyloid beta peptide and iron/hydrogen peroxide toxicity by alpha lipoic acid. J Alzheimers Dis, 2003; 5:229-239.
-
(2003)
J Alzheimers Dis
, vol.5
, pp. 229-239
-
-
Lovell, M.A.1
Xie, C.2
Xiong, S.3
Markesbery, W.R.4
-
28
-
-
0038681645
-
Effects of acetyl-l-carnitine in alzheimer’s disease patients unresponsive to acetylcholinesterase inhibitors
-
Bianchetti A, Rozzini R, Trabucchi M. Effects of acetyl-L-carnitine in Alzheimer’s disease patients unresponsive to acetylcholinesterase inhibitors. Curr Med Res Opin, 2003; 19:350-353.
-
(2003)
Curr Med Res Opin
, vol.19
, pp. 350-353
-
-
Bianchetti, A.1
Rozzini, R.2
Trabucchi, M.3
-
29
-
-
0037347231
-
Meta-analysis of double blind randomized controlled clinical trials of acetyl-l-carnitine versus placebo in the treatment of mild cognitive impairment and mild alzheimer’s disease
-
Montgomery SA, Thal LJ, Amrein R. Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer’s disease. Int Clin Psychopharmacol, 2003; 18: 61-71.
-
(2003)
Int Clin Psychopharmacol
, vol.18
, pp. 61-71
-
-
Montgomery, S.A.1
Thal, L.J.2
Amrein, R.3
-
31
-
-
0031593616
-
Sustained efficacy and safety of idebenone in the treatment of alzheimer’s disease: Update on a 2-year double-blind multicentre study
-
Gutzmann H, Hadler D. Sustained efficacy and safety of idebenone in the treatment of Alzheimer’s disease: update on a 2-year double-blind multicentre study. J Neural Transm Suppl, 1998; 54:301-310.
-
(1998)
J Neural Transm Suppl
, vol.54
, pp. 301-310
-
-
Gutzmann, H.1
Hadler, D.2
-
32
-
-
0030758077
-
A controlled study of 2 doses of idebenone in the treatment of alzheimer’s disease
-
Weyer G, Babej-Dolle RM, Hadler D, Hofmann S, Herrmann WM. A controlled study of 2 doses of idebenone in the treatment of Alzheimer’s disease. Neuropsychobiology, 1997; 36:73-82.
-
(1997)
Neuropsychobiology
, vol.36
, pp. 73-82
-
-
Weyer, G.1
Babej-Dolle, R.M.2
Hadler, D.3
Hofmann, S.4
Herrmann, W.M.5
-
33
-
-
0036172871
-
Safety and efficacy of idebenone versus tacrine in patients with alzheimer’s disease: Results of a randomized, doubleblind, parallel-group multicenter study
-
Gutzmann H, Kuhl KP, Hadler D, Rapp MA. Safety and efficacy of idebenone versus tacrine in patients with Alzheimer’s disease: results of a randomized, doubleblind, parallel-group multicenter study. Pharmacopsychiatry, 2002; 35:12-18.
-
(2002)
Pharmacopsychiatry
, vol.35
, pp. 12-18
-
-
Gutzmann, H.1
Kuhl, K.P.2
Hadler, D.3
Rapp, M.A.4
-
34
-
-
0344738681
-
Idebenone treatment fails to slow cognitive decline in alzheimer’s disease
-
Thal LJ, Grundman M, Berg J, Ernstrom K, Margolin R, Pfeiffer E, Weiner MF, Zamrini E, Thomas RG. Idebenone treatment fails to slow cognitive decline in Alzheimer’s disease. Neurology, 2003; 61:1498-1502.
-
(2003)
Neurology
, vol.61
, pp. 1498-1502
-
-
Thal, L.J.1
Grundman, M.2
Berg, J.3
Ernstrom, K.4
Margolin, R.5
Pfeiffer, E.6
Weiner, M.F.7
Zamrini, E.8
Thomas, R.G.9
-
35
-
-
0344826082
-
Prevention of age-related spatial memory deficits in a transgenic mouse model of alzheimer’s disease by chronic ginkgo biloba treatment
-
Stackman RW, Eckenstein F, Frei B, Kulhanek D, Nowlin J, Quinn JF. Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimer’s disease by chronic Ginkgo biloba treatment. Exp Neurol, 2003; 184:510-520.
-
(2003)
Exp Neurol
, vol.184
, pp. 510-520
-
-
Stackman, R.W.1
Eckenstein, F.2
Frei, B.3
Kulhanek, D.4
Nowlin, J.5
Quinn, J.F.6
-
36
-
-
0030759072
-
A placebo-controlled, double-blind, randomized trial of an extract of ginkgo biloba for dementia. North american egb study group
-
Le Bars PL, Katz MM, Berman N, Itil TM, Freedman AM, Schatzberg AF. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group. JAMA, 1997; 278:1327-1332.
-
(1997)
JAMA
, vol.278
, pp. 1327-1332
-
-
Le Bars, P.L.1
Katz, M.M.2
Berman, N.3
Itil, T.M.4
Freedman, A.M.5
Schatzberg, A.F.6
-
37
-
-
0030967165
-
Controlled trial of selegiline, alpha-tocopherol, or both as treatment for alzheimer’s disease. The alzheimer’s disease cooperative study
-
Sano M, Ernesto C, Thomas RG, Klauber MR, Schafer K, Grundman M, Woodbury P, Growdon J, Cotman CW, Pfeiffer E, Schneider LS, Thal LJ. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer’s disease. The Alzheimer’s Disease Cooperative Study. N Engl J Med, 1997; 336:1216-1222.
-
(1997)
N Engl J Med
, vol.336
, pp. 1216-1222
-
-
Sano, M.1
Ernesto, C.2
Thomas, R.G.3
Klauber, M.R.4
Schafer, K.5
Grundman, M.6
Woodbury, P.7
Growdon, J.8
Cotman, C.W.9
Pfeiffer, E.10
Schneider, L.S.11
Thal, L.12
-
38
-
-
0033958696
-
Vitamin e and alzheimer disease: The basis for additional clinical trials
-
Grundman M. Vitamin E and Alzheimer disease: the basis for additional clinical trials. Am J Clin Nutr, 2000; 71:630S-636S.
-
(2000)
Am J Clin Nutr
, vol.71
, pp. 630S-636S
-
-
Grundman, M.1
-
39
-
-
0037178573
-
Dietary intake of antioxidants and risk of alzheimer disease
-
Engelhart MJ, Geerlings MI, Ruitenberg A, van Swieten JC, Hofman A, Witteman JC, Breteler MM. Dietary intake of antioxidants and risk of Alzheimer disease. JAMA, 2002; 287:3223-3229.
-
(2002)
JAMA
, vol.287
, pp. 3223-3229
-
-
Engelhart, M.J.1
Geerlings, M.I.2
Ruitenberg, A.3
Van Swieten, J.C.4
Hofman, A.5
Witteman, J.C.6
Breteler, M.M.7
-
40
-
-
0037178579
-
Dietary intake of antioxidant nutrients and the risk of incident alzheimer disease in a biracial community study
-
Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Aggarwal N, Wilson RS, Scherr PA. Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. JAMA, 2002; 287:3230-3237.
-
(2002)
JAMA
, vol.287
, pp. 3230-3237
-
-
Morris, M.C.1
Evans, D.A.2
Bienias, J.L.3
Tangney, C.C.4
Bennett, D.A.5
Aggarwal, N.6
Wilson, R.S.7
Scherr, P.A.8
-
41
-
-
0346688728
-
Reduced risk of alzheimer disease in users of antioxidant vitamin supplements: The cache county study
-
Zandi PP, Anthony JC, Khachaturian AS, Stone SV, Gustafson D, Tschanz JT, Norton MC, Welsh-Bohmer KA, Breitner JC. Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: the Cache County Study. Arch Neurol, 2004; 61:82-88.
-
(2004)
Arch Neurol
, vol.61
, pp. 82-88
-
-
Zandi, P.P.1
Anthony, J.C.2
Khachaturian, A.S.3
Stone, S.V.4
Gustafson, D.5
Tschanz, J.T.6
Norton, M.C.7
Welsh-Bohmer, K.A.8
Breitner, J.C.9
-
42
-
-
0037320324
-
Antioxidant vitamin intake and risk of alzheimer disease
-
Luchsinger JA, Tang MX, Shea S, Mayeux R. Antioxidant vitamin intake and risk of Alzheimer disease. Arch Neurol, 2003; 60:203-208.
-
(2003)
Arch Neurol
, vol.60
, pp. 203-208
-
-
Luchsinger, J.A.1
Tang, M.X.2
Shea, S.3
Mayeux, R.4
-
43
-
-
2342608923
-
Midlife dietary intake of antioxidants and risk of late-life incident dementia: The honolulu-asia aging study
-
Laurin D, Masaki KH, Foley DJ, White LR, Launer LJ. Midlife dietary intake of antioxidants and risk of late-life incident dementia: the Honolulu-Asia Aging Study. Am J Epidemiol, 2004; 159:959-967.
-
(2004)
Am J Epidemiol
, vol.159
, pp. 959-967
-
-
Laurin, D.1
Masaki, K.H.2
Foley, D.J.3
White, L.R.4
Launer, L.J.5
-
44
-
-
0036350741
-
Estrogen and alzheimer’s disease: The story so far
-
Cholerton B, Gleason CE, Baker LD, Asthana S. Estrogen and Alzheimer’s disease: the story so far. Drugs Aging, 2002; 19:405-427.
-
(2002)
Drugs Aging
, vol.19
, pp. 405-427
-
-
Cholerton, B.1
Gleason, C.E.2
Baker, L.D.3
Asthana, S.4
-
45
-
-
0035964288
-
High-dose estradiol improves cognition for women with ad: Results of a randomized study
-
Asthana S, Baker LD, Craft S, Stanczyk FZ, Veith RC, Raskind MA, Plymate SR. High-dose estradiol improves cognition for women with AD: results of a randomized study. Neurology, 2001; 57:605-612.
-
(2001)
Neurology
, vol.57
, pp. 605-612
-
-
Asthana, S.1
Baker, L.D.2
Craft, S.3
Stanczyk, F.Z.4
Veith, R.C.5
Raskind, M.A.6
Plymate, S.R.7
-
46
-
-
84903136614
-
Asthana s. 17beta-estradiol reduces plasma abeta40 for hrt-naive postmenopausal women with alzheimer disease: A preliminary study
-
Baker LD, Sambamurti K, Craft S, Cherrier M, Raskind MA, Stanczyk FZ, Plymate SR, Asthana S. 17beta-estradiol reduces plasma Abeta40 for HRT-naive postmenopausal women with Alzheimer disease: a preliminary study. Am J Geriatr Psychiatr, 2003; 11:239-244.
-
(2003)
Am J Geriatr Psychiatr
, vol.11
, pp. 239-244
-
-
Baker, L.D.1
Sambamurti, K.2
Craft, S.3
Cherrier, M.4
Raskind, M.A.5
Stanczyk, F.Z.6
Plymate, S.R.7
-
47
-
-
0038077567
-
Endogenous estradiol and risk of dementia in women and men: The rotterdam study
-
Geerlings MI, Launer LJ, de Jong FH, Ruitenberg A, Stijnen T, van Swieten JC, Hofman A, Witteman JC, Pols HA, Breteler MM. Endogenous estradiol and risk of dementia in women and men: the Rotterdam Study. Ann Neurol, 2003; 53:607-615.
-
(2003)
Ann Neurol
, vol.53
, pp. 607-615
-
-
Geerlings, M.I.1
Launer, L.J.2
De Jong, F.H.3
Ruitenberg, A.4
Stijnen, T.5
Van Swieten, J.C.6
Hofman, A.7
Witteman, J.C.8
Pols, H.A.9
Breteler, M.M.10
-
48
-
-
0037320796
-
Estrogen levels do not correlate with improvement in cognition
-
Thal LJ, Thomas RG, Mulnard R, Sano M, Grundman M, Schneider L. Estrogen levels do not correlate with improvement in cognition. Arch Neurol, 2003; 60:209-212.
-
(2003)
Arch Neurol
, vol.60
, pp. 209-212
-
-
Thal, L.J.1
Thomas, R.G.2
Mulnard, R.3
Sano, M.4
Grundman, M.5
Schneider, L.6
-
49
-
-
0035503597
-
The curry spice curcumin reduces oxidative damage and amyloid pathology in an alzheimer transgenic mouse
-
Lim GP, Chu T, Yang F, Beech W, Frautschy SA, Cole GM. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci, 2001; 21:8370-8377.
-
(2001)
J Neurosci
, vol.21
, pp. 8370-8377
-
-
Lim, G.P.1
Chu, T.2
Yang, F.3
Beech, W.4
Frautschy, S.A.5
Cole, G.M.6
-
50
-
-
0036741254
-
Discovery of natural products from curcuma longa that protect cells from beta-amyloid insult: A drug discovery effort against alzheimer’s disease
-
Park SY, Kim DS. Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: a drug discovery effort against Alzheimer’s disease. J Nat Prod, 2002; 65:1227-1231.
-
(2002)
J Nat Prod
, vol.65
, pp. 1227-1231
-
-
Park, S.Y.1
Kim, D.S.2
-
51
-
-
1542364225
-
Curcumin has potent anti-amyloidogenic effects for alzheimer’s beta-amyloid fibrils in vitro
-
Ono K, Hasegawa K, Naiki H, Yamada M. Curcumin has potent anti-amyloidogenic effects for Alzheimer’s beta-amyloid fibrils in vitro. J Neurosci Res, 2004; 75:742-750.
-
(2004)
J Neurosci Res
, vol.75
, pp. 742-750
-
-
Ono, K.1
Hasegawa, K.2
Naiki, H.3
Yamada, M.4
-
52
-
-
0031947574
-
Oxidized lipoproteins may play a role in neuronal cell death in alzheimer disease
-
Draczynska-Lusiak B, Doung A, Sun AY. Oxidized lipoproteins may play a role in neuronal cell death in Alzheimer disease. Mol Chem Neuropathol, 1998; 33:139-148.
-
(1998)
Mol Chem Neuropathol
, vol.33
, pp. 139-148
-
-
Draczynska-Lusiak, B.1
Doung, A.2
Sun, A.Y.3
-
53
-
-
0344394951
-
Red wine ingredient resveratrol protects from beta-amyloid neurotoxicity
-
Savaskan E, Olivieri G, Meier F, Seifritz E, Wirz-Justice A, Muller-Spahn F. Red wine ingredient resveratrol protects from beta-amyloid neurotoxicity. Gerontology, 2003; 49:380-383.
-
(2003)
Gerontology
, vol.49
, pp. 380-383
-
-
Savaskan, E.1
Olivieri, G.2
Meier, F.3
Seifritz, E.4
Wirz-Justice, A.5
Muller-Spahn, F.6
-
54
-
-
0034986151
-
Protection against beta-amyloid peptide toxicity in vivo with long-term administration of ferulic acid
-
Yan JJ, Cho JY, Kim HS, Kim KL, Jung JS, Huh SO, Suh HW, Kim YH, Song DK. Protection against beta-amyloid peptide toxicity in vivo with long-term administration of ferulic acid. Br J Pharmacol, 2001; 133:89-96.
-
(2001)
Br J Pharmacol
, vol.133
, pp. 89-96
-
-
Yan, J.J.1
Cho, J.Y.2
Kim, H.S.3
Kim, K.L.4
Jung, J.S.5
Huh, S.O.6
Suh, H.W.7
Kim, Y.H.8
Song, D.K.9
-
55
-
-
1942519702
-
Attenuation of chronic neuroinflammation by a nitric oxide-releasing derivative of the antioxidant ferulic acid
-
Wenk GL, McGann-Gramling K, Hauss-Wegrzyniak B, Ronchetti D, Maucci R, Rosi S, Gasparini L, Ongini E. Attenuation of chronic neuroinflammation by a nitric oxide-releasing derivative of the antioxidant ferulic acid. J Neurochem, 2004; 89:484-493.
-
(2004)
J Neurochem
, vol.89
, pp. 484-493
-
-
Wenk, G.L.1
McG-GRAMLINGann-Gramling, K.2
Hauss-Wegrzyniak, B.3
Ronchetti, D.4
Maucci, R.5
Rosi, S.6
Gasparini, L.7
Ongini, E.8
-
56
-
-
0033964859
-
In situ oxidative catalysis by neurofibrillary tangles and senile plaques in alzheimer’s disease: A central role for bound transition metals
-
Sayre LM, Perry G, Harris PL, Liu Y, Schubert KA, Smith MA. In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer’s disease: a central role for bound transition metals. J Neurochem, 2000; 74:270-279.
-
(2000)
J Neurochem
, vol.74
, pp. 270-279
-
-
Sayre, L.M.1
Perry, G.2
Harris, P.L.3
Liu, Y.4
Schubert, K.A.5
Smith, M.A.6
-
57
-
-
0031921496
-
Reversal by desferrioxamine of tau protein aggregates following two days of treatment in aluminum-induced neurofibrillary degeneration in rabbit: Implications for clinical trials in alzheimer’s disease
-
Savory J, Huang Y, Wills MR, Herman MM. Reversal by desferrioxamine of tau protein aggregates following two days of treatment in aluminum-induced neurofibrillary degeneration in rabbit: implications for clinical trials in Alzheimer’s disease. Neurotoxicology, 1998; 19:209-214.
-
(1998)
Neurotoxicology
, vol.19
, pp. 209-214
-
-
Savory, J.1
Huang, Y.2
Wills, M.R.3
Herman, M.M.4
-
58
-
-
0027515763
-
Desferrioxamine and alzheimer’s disease: Video home behavior assessment of clinical course and measures of brain aluminum
-
McLachlan DR, Smith WL, Kruck TP. Desferrioxamine and Alzheimer’s disease: video home behavior assessment of clinical course and measures of brain aluminum. Ther Drug Monit, 1993; 15:602-607.
-
(1993)
Ther Drug Monit
, vol.15
, pp. 602-607
-
-
McLachlan, D.R.1
Smith, W.L.2
Kruck, T.P.3
-
59
-
-
0026050541
-
Would decreased aluminum ingestion reduce the incidence of alzheimer’s disease?
-
McLachlan DR, Kruck TP, Lukiw WJ, Krishnan SS. Would decreased aluminum ingestion reduce the incidence of Alzheimer’s disease? CMAJ, 1991; 145:793-804.
-
(1991)
CMAJ
, vol.145
, pp. 793-804
-
-
McLachlan, D.R.1
Kruck, T.P.2
Lukiw, W.J.3
Krishnan, S.S.4
-
60
-
-
0034964390
-
Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in alzheimer’s disease transgenic mice
-
Cherny RA, Atwood CS, Xilinas ME, Gray DN, Jones WD, McLean CA, Barnham KJ, Volitakis I, Fraser FW, Kim Y, Huang X, Goldstein LE, Moir RD, Lim JT, Beyreuther K, Zheng H, Tanzi RE, Masters CL, Bush AI. Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer’s disease transgenic mice. Neuron, 2001; 30:665-676.
-
(2001)
Neuron
, vol.30
, pp. 665-676
-
-
Cherny, R.A.1
Atwood, C.S.2
Xilinas, M.E.3
Gray, D.N.4
Jones, W.D.5
McLean, C.A.6
Barnham, K.J.7
Volitakis, I.8
Fraser, F.W.9
Kim, Y.10
Huang, X.11
Goldstein, L.E.12
Moir, R.D.13
Lim, J.T.14
Beyreuther, K.15
Zheng, H.16
Tanzi, R.E.17
Masters, C.L.18
Bush, A.I.19
-
61
-
-
10744224267
-
Metal-protein attenuation with iodochlorhydroxyquin (Clioquinol) targeting abeta amyloid deposition and toxicity in alzheimer disease: A pilot phase 2 clinical trial
-
Ritchie CW, Bush AI, Mackinnon A, Macfarlane S, Mastwyk M, MacGregor L, Kiers L, Cherny R, Li QX, Tammer A, Carrington D, Mavros C, Volitakis I, Xilinas M, Ames D, Davis S, Beyreuther K, Tanzi RE, Masters CL. Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Arch Neurol, 2003; 60:1685-1691.
-
(2003)
Arch Neurol
, vol.60
, pp. 1685-1691
-
-
Ritchie, C.W.1
Bush, A.I.2
Mackinnon, A.3
Macfarlane, S.4
Mastwyk, M.5
MacGregor, L.6
Kiers, L.7
Cherny, R.8
Li, Q.X.9
Tammer, A.10
Carrington, D.11
Mavros, C.12
Volitakis, I.13
Xilinas, M.14
Ames, D.15
Davis, S.16
Beyreuther, K.17
Tanzi, R.E.18
Masters, C.L.19
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