(r)-, but not (s)-alpha lipoic acid stimulates deficient brain pyruvate dehydrogenase complex in vascular dementia, but not in Alzheimer dementia

Journal of Neural Transmission

Volumn 111, Issue 3, 2004, Pages 295-310

  Frolich L ^a,d   Gotz M E ^b   Weinmuller M ^c   Youdim, M B H ^c   Barth, N ^b   Dirr, A ^b   Gsell, W ^b   Jellinger, K ^c   Beckmann, H ^b   Riederer, P ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^d Ctrl Institute of Mental Health   (Germany)

Author keywords

Alpha lipoic acid; Dementia of Alzheimer type; Dementia of vascular type; Post mortem human brain; Pyruvate dehydrogenase complex; Succinate dehydrogenase

Indexed keywords

ENZYME ACTIVATOR; PYRUVATE DEHYDROGENASE; THIOCTIC ACID;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN METABOLISM; CADAVER; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; GLUCOSE METABOLISM; HUMAN; HUMAN TISSUE; INHIBITION KINETICS; MALE; MULTIINFARCT DEMENTIA; NIEMANN PICK DISEASE; PARIETAL LOBE; PRIORITY JOURNAL; STEREOISOMERISM;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; CADAVER; CASE-CONTROL STUDIES; DEMENTIA, VASCULAR; ENZYME ACTIVATION; FEMALE; HUMANS; MALE; PARIETAL LOBE; PYRUVATE DEHYDROGENASE COMPLEX; SUCCINATE DEHYDROGENASE; THIOCTIC ACID;

EID: 12144290583     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00702-003-0043-5     Document Type: Article

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