Ampelopsin induces cell growth inhibition and apoptosis in breast cancer cells through ROS generation and endoplasmic reticulum stress pathway

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Zhou, Yong ^a   Shu, Furong ^a   Liang, Xinyu ^a   Chang, Hui ^a   Shi, Linying ^a   Peng, Xiaoli ^a   Zhu, Jundong ^a   Mi, Mantian ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMPELOPSIN; ANTINEOPLASTIC AGENT; GLUCOSE REGULATED PROTEIN 78; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

AMPELOPSIS; AMPELOPSIS GROSSEDENTATA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL GROWTH; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; ENDOPLASMIC RETICULUM STRESS; GROWTH INHIBITION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; RNA INTERFERENCE; UPREGULATION;

ACETYLCYSTEINE; ACTIVATING TRANSCRIPTION FACTOR 6; AMPELOPSIS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; FEMALE; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAT-SHOCK PROTEINS; HUMANS; PHENYLBUTYRATES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THAPSIGARGIN; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS;

EID: 84895829916     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089021     Document Type: Article

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