Saxifragifolin D induces the interplay between apoptosis and autophagy in breast cancer cells through ROS-dependent endoplasmic reticulum stress

Biochemical Pharmacology

Volumn 85, Issue 7, 2013, Pages 913-926

  Shi, Jun Min ^a   Bai, Liang Liang ^a   Zhang, Dong Mei ^a   Yiu, Anita ^b   Yin, Zhi Qi ^c   Han, Wei Li ^a   Liu, Jun Shan ^a   Li, Yong ^a   Fu, Deng Yue ^a   Ye, Wen Cai ^a  

^a JINAN UNIVERSITY   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; Breast cancer; Endoplasmic reticulum stress; Saxifragifolin D

Indexed keywords

ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; BAFILOMYCIN A1; BECLIN 1; CALNEXIN; CALPAIN; CASPASE 3; CASPASE 9; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN IRE1; REACTIVE OXYGEN METABOLITE; SAXIFRAGIFOLIN D; TAUROURSODEOXYCHOLIC ACID; TRITERPENOID; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BREAST CANCER; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL STRAIN MCF 7; CELL SURVIVAL; CELL VIABILITY; COLONY FORMATION; CONTROLLED STUDY; DISSOCIATION; ELECTRIC POTENTIAL; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; IN VITRO STUDY; LYSOSOME; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; UPREGULATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; AUTOPHAGY; BREAST NEOPLASMS; CALCIUM; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOSOL; ENDOPLASMIC RETICULUM STRESS; FEMALE; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE OXYGEN SPECIES; SAPONINS;

EID: 84874656598     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.01.009     Document Type: Article

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