Enhanced cytotoxicity of optimized liposomal genistein via specific induction of apoptosis in breast, ovarian and prostate carcinomas

Journal of Drug Targeting

Volumn 21, Issue 10, 2013, Pages 1001-1011

  Phan, Vu ^a   Walters, Jarvis ^a   Brownlow, Bill ^b   Elbayoumi, Tamer ^b  

^a MIDWESTERN UNIVERSITY   (United States)

^b MIDWESTERN UNIVERSITY   (United States)

Author keywords

Caspase; Cytotoxic; Factorial design; Isoflavone; Liposomes; Nutraceutical; Phospholipid bi layer; Pro apoptosis

Indexed keywords

GENISTEIN; LIPOSOME; PHOSPHOLIPID;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; BREAST CARCINOMA; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DRUG HALF LIFE; DRUG SOLUBILITY; DRUG STRUCTURE; EXPERIMENTAL DESIGN; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; OVARY CARCINOMA; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROSTATE CARCINOMA; REVIEW; SOLUBILIZATION;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CHOLESTEROL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; DRUG STABILITY; FEMALE; GENISTEIN; HUMANS; INHIBITORY CONCENTRATION 50; LIPOSOMES; MALE; MICE; OVARIAN NEOPLASMS; PHOSPHOLIPIDS; PROSTATIC NEOPLASMS; SOLUBILITY; TIME FACTORS;

EID: 84887216989     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2013.847099     Document Type: Review

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