Neferine from Nelumbo nucifera induces autophagy through the inhibition of PI3K/Akt/mTOR pathway and ROS hyper generation in A549 cells

Food Chemistry

Volumn 141, Issue 4, 2013, Pages 3598-3605

  Poornima, Paramasivan ^a   Weng, Ching Feng ^b   Padma, Viswanadha Vijaya ^a  

^a BHARATHIAR UNIVERSITY   (India)

^b NATIONAL DONG HWA UNIVERSITY   (Taiwan)

Author keywords

Autophagy; GSH; MTOR; Neferine; ROS

Indexed keywords

ANTIBIOTICS; BIOLOGICAL ORGANS; CELL DEATH; CELL PROLIFERATION; CYTOLOGY; DISEASES;

ACTION MECHANISMS; AUTOPHAGY; DOSE-DEPENDENT MANNER; EXPRESSION LEVELS; LUNG CANCER CELLS; MECHANISM OF ACTION; MTOR; NEFERINE;

CELLS;

BECLIN 1; GLUTATHIONE; MAMMALIAN TARGET OF RAPAMYCIN; NEFERINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; AUTOPHAGY; CELL VIABILITY; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG CANCER; NELUMBO NUCIFERA;

NELUMBO NUCIFERA;

AUTOPHAGY; GSH; MTOR; NEFERINE; ROS;

APOPTOSIS; AUTOPHAGY; BENZYLISOQUINOLINES; CELL LINE, TUMOR; DOWN-REGULATION; HUMANS; NELUMBO; NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84884538218     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2013.05.138     Document Type: Article

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