DNA polymerases engineered by directed evolution to incorporate nonstandard nucleotides

Frontiers in Microbiology

Volumn 5, Issue OCT, 2014, Pages

  Laos, Roberto ^a   Thomson, J Michael ^a   Benner, Steven A ^a  

^a FOUNDATION FOR APPLIED MOLECULAR EVOLUTION   (United States)

Author keywords

AEGIS; CSR; Directed evolution; DNA polymerases; Nonstandard nucleotides; Protein engineering

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA; DNA POLYMERASE; NONSTANDARD NUCLEOTIDE; NUCLEOTIDE; RNA DIRECTED DNA POLYMERASE; RNA POLYMERASE; TAQ POLYMERASE; UNCLASSIFIED DRUG;

BACTERIOPHAGE T7; CELL COMPARTMENTALIZATION; CODON; CONFORMATIONAL TRANSITION; CRYSTALLOGRAPHY; DIRECTED MOLECULAR EVOLUTION; DNA DAMAGE; DNA REPAIR; DNA SEQUENCE; DNA SHUFFLING; DNA STRAND; DNA STRAND BREAKAGE; MOLECULAR EVOLUTION; MOLECULAR RECOGNITION; POINT MUTATION; POLYMERASE CHAIN REACTION; PROTEIN ENGINEERING; REVIEW; SEQUENCE ALIGNMENT; THERMOSTABILITY;

EID: 84910025847     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2014.00565     Document Type: Review

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