Conferring RNA polymerase activity to a DNA polymerase: A single residue in reverse transcriptase controls substrate selection

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 2, 1997, Pages 407-411

  Gao, Guangxia ^a   Orlova, Marianna ^a   Georgiadis, Millie M ^b   Hendrickson, Wayne A ^a   Goff, Stephen P ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

deoxyribonucleotides; DNA synthesis

Indexed keywords

DEOXYRIBONUCLEOTIDE; DNA POLYMERASE; ENZYME VARIANT; RIBONUCLEOTIDE; RNA DIRECTED DNA POLYMERASE; RNA POLYMERASE;

ARTICLE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME MODIFICATION; ENZYME STRUCTURE; NONHUMAN; NUCLEIC ACID SYNTHESIS; PRIORITY JOURNAL;

BINDING SITES; DNA-DIRECTED DNA POLYMERASE; DNA-DIRECTED RNA POLYMERASES; KINETICS; MODELS, MOLECULAR; MOLONEY MURINE LEUKEMIA VIRUS; PHENYLALANINE; POINT MUTATION; RNA-DIRECTED DNA POLYMERASE; SUBSTRATE SPECIFICITY; TYROSINE; VALINE;

MOLONEY MURINE LEUKEMIA VIRUS; MURINAE;

EID: 0031028380     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.2.407     Document Type: Article

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