Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice

Neurobiology of Disease

Volumn 73, Issue , 2015, Pages 275-288

  Papadopoulou, Aikaterini S ^a,b   Serneels, Lutgarde ^a,b   Achsel, Tilmann ^a,b   Mandemakers, Wim ^f   Callaerts Vegh, Zsuzsanna ^c   Dooley, James ^c   Lau, Pierre ^a,b   Ayoubi, Torik ^a,b,e   Radaelli, Enrico ^a,b   Spinazzi, Marco ^a,b   Neumann, Melanie ^d   Hébert, Sébastien S ^g,h   Silahtaroglu, Asli ⁱ   Liston, Adrian ^c   D'Hooge, Rudi ^b,c   Glatzel, Markus ^c   De Strooper, Bart ^a,b,j  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e SAINT JAMES SCHOOL OF MEDICINE   (Anguilla)

^f ERASMUS MEDICAL CENTER   (Netherlands)

^g Université Laval   (Canada)

^h UNIVERSITÉ LAVAL   (Canada)

ⁱ UNIVERSITY OF COPENHAGEN   (Denmark)

^j UNIVERSITY COLLEGE LONDON   (United Kingdom)

more..

Author keywords

Ataxia; Cerebellum; Dendrites; Locomotor behavior; MiR 29a b 1 cluster knockout; Purkinje cells; Voltage gated potassium channel

Indexed keywords

MICRORNA 29A; MICRORNA 29B; MIR 29B 1; POTASSIUM CHANNEL KV3.3; VOLTAGE GATED POTASSIUM CHANNEL; KCNC3 PROTEIN, MOUSE; MICRORNA; MIRN29 MICRORNA, MOUSE; SHAW POTASSIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ATAXIA; CELL STRUCTURE; CEREBELLUM; CONTROLLED STUDY; DENDRITIC CELL; GENE EXPRESSION; GENE INACTIVATION; HIPPOCAMPUS; LOCOMOTION; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; OLFACTORY BULB; PURKINJE CELL; SYNAPSE; UPREGULATION; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; KNOCKOUT MOUSE; METABOLISM; MOTOR ACTIVITY;

ANIMALS; ATAXIA; BEHAVIOR, ANIMAL; CEREBELLUM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRORNAS; MOTOR ACTIVITY; PURKINJE CELLS; SHAW POTASSIUM CHANNELS;

EID: 84908701662     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.10.006     Document Type: Article

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